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Conserved domains on  [gi|1236169540|ref|WP_094962434|]
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MULTISPECIES: GNAT family N-acetyltransferase [Providencia]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11441181)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-146 5.85e-24

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


:

Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 91.21  E-value: 5.85e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540   1 MIREAIKSDVESILSLY-QILFSEMALFDPERLQPAEQTREFieNAIIDDKFCLLVAEFNSEIKGFCiaqqqAADPYNCV 79
Cdd:COG1247     3 TIRPATPEDAPAIAAIYnEAIAEGTATFETEPPSEEEREAWF--AAILAPGRPVLVAEEDGEVVGFA-----SLGPFRPR 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1236169540  80 VPRNFGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVLAQNHKAIKFYEREGLTEISR 146
Cdd:COG1247    76 PAYRGTAEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLGFEEVGT 142
 
Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-146 5.85e-24

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 91.21  E-value: 5.85e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540   1 MIREAIKSDVESILSLY-QILFSEMALFDPERLQPAEQTREFieNAIIDDKFCLLVAEFNSEIKGFCiaqqqAADPYNCV 79
Cdd:COG1247     3 TIRPATPEDAPAIAAIYnEAIAEGTATFETEPPSEEEREAWF--AAILAPGRPVLVAEEDGEVVGFA-----SLGPFRPR 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1236169540  80 VPRNFGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVLAQNHKAIKFYEREGLTEISR 146
Cdd:COG1247    76 PAYRGTAEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLGFEEVGT 142
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 13-140 3.70e-15

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 67.16  E-value: 3.70e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540  13 ILSLYQILFSEMALFDPERLQPAeqtrefIENAIIDDKFCLLVAEFNSEIKGFCIAqqqaadpYNCVVPRNFGYIFDLVV 92
Cdd:pfam00583   1 LEALYELLSEEFPEPWPDEPLDL------LEDWDEDASEGFFVAEEDGELVGFASL-------SIIDDEPPVGEIEGLAV 67

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1236169540  93 APNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVLAQNHKAIKFYEREG 140
Cdd:pfam00583  68 APEYRGKGIGTALLQALLEWARERGCERIFLEVAADNLAAIALYEKLG 115
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 53-124 2.19e-09

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 50.74  E-value: 2.19e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236169540  53 LLVAEFNSEIKGFCIAQQQAADPyncvvprNFGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELS 124
Cdd:cd04301     1 FLVAEDDGEIVGFASLSPDGSGG-------DTAYIGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRLE 65
PRK10975 PRK10975
dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase;
33-147 2.83e-07

dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase;


Pssm-ID: 182877  Cd Length: 194  Bit Score: 47.62  E-value: 2.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540  33 QPAEQTR---EFIENAIID--DKFCLLVAEFNSEIKGFCIAQQQAAdpyncvvprNFGYIFDLVVAPNFRGEKAGQKLLN 107
Cdd:PRK10975   79 APDDSGRfyaQWIENAVRGtfDHQCLLLRDASGQIQGFVTLRELND---------TDARIGLLAVFPGAQGRGIGARLMQ 149

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1236169540 108 AMKAWAKSRQLSHLELSVLAQNHKAIKFYEREGLTeISRT 147
Cdd:PRK10975  150 AALNWCQARGLTRLRVATQMGNLAALRLYIRSGAN-IEST 188
PseH TIGR03585
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase; Sequences in this ...
 101-142 2.41e-03

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase; Sequences in this family are members of the pfam00583 (GNAT) superfamily of acetyltransferases and are proposed to perform a N-acetylation step in the process of pseudaminic acid biosynthesis in Campylobacter species. This gene is commonly observed in apparent operons with other genes responsible for the biosynthesis of pseudaminic acid and as a component of flagellar and exopolysaccharide biosynthesis loci. Significantly, many genomes containing other components of this pathway lack this gene, indicating that some other N-acetyl transferases may be incolved and/or the step is optional, resulting in a non-acetylated pseudaminic acid variant sugar.


Pssm-ID: 274661 [Multi-domain]  Cd Length: 152  Bit Score: 36.18  E-value: 2.41e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1236169540 101 AGQKLLNAMKAWAKSR-QLSHLELSVLAQNHKAIKFYEREGLT 142
Cdd:TIGR03585  92 VGSVLEEAALEYAFEHlGLHKLSLEVLESNNKALKLYEKFGFE 134
 
Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-146 5.85e-24

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 91.21  E-value: 5.85e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540   1 MIREAIKSDVESILSLY-QILFSEMALFDPERLQPAEQTREFieNAIIDDKFCLLVAEFNSEIKGFCiaqqqAADPYNCV 79
Cdd:COG1247     3 TIRPATPEDAPAIAAIYnEAIAEGTATFETEPPSEEEREAWF--AAILAPGRPVLVAEEDGEVVGFA-----SLGPFRPR 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1236169540  80 VPRNFGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVLAQNHKAIKFYEREGLTEISR 146
Cdd:COG1247    76 PAYRGTAEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLGFEEVGT 142
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 64-149 3.03e-18

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 74.31  E-value: 3.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540  64 GFCIAQQQAADPYncvvprnfGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVLAQNHKAIKFYEREGLTE 143
Cdd:COG0456     1 GFALLGLVDGGDE--------AEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALYEKLGFEE 72


                  ....*.
gi 1236169540 144 ISRTMG 149
Cdd:COG0456    73 VGERPN 78
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 28-146 3.01e-16

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 70.47  E-value: 3.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540  28 DPERLQPAEQTREFIENAII-DDKFCLLVAEFNSEIKGFCIAQQqaadpyncvVPRNFGYIFDLVVAPNFRGEKAGQKLL 106
Cdd:COG0454    10 DINFILLIEALDAELKAMEGsLAGAEFIAVDDKGEPIGFAGLRR---------LDDKVLELKRLYVLPEYRGKGIGKALL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1236169540 107 NAMKAWAKSRQLSHLELSVLAQNHKAIKFYEREGLTEISR 146
Cdd:COG0454    81 EALLEWARERGCTALELDTLDGNPAAIRFYERLGFKEIER 120
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 13-140 3.70e-15

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 67.16  E-value: 3.70e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540  13 ILSLYQILFSEMALFDPERLQPAeqtrefIENAIIDDKFCLLVAEFNSEIKGFCIAqqqaadpYNCVVPRNFGYIFDLVV 92
Cdd:pfam00583   1 LEALYELLSEEFPEPWPDEPLDL------LEDWDEDASEGFFVAEEDGELVGFASL-------SIIDDEPPVGEIEGLAV 67

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1236169540  93 APNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVLAQNHKAIKFYEREG 140
Cdd:pfam00583  68 APEYRGKGIGTALLQALLEWARERGCERIFLEVAADNLAAIALYEKLG 115
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 1-147 2.80e-13

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 62.70  E-value: 2.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540   1 MIREAIKSDVESILSLYQilfsemalfdperlqpaeqtrefiENAIIDDKFCLLVAEFNSEIKGFCiaqqqAADPYncvv 80
Cdd:COG1246     2 TIRPATPDDVPAILELIR------------------------PYALEEEIGEFWVAEEDGEIVGCA-----ALHPL---- 48

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1236169540  81 PRNFGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVlaqNHKAIKFYEREGLTEISRT 147
Cdd:COG1246    49 DEDLAELRSLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLT---TSAAIHFYEKLGFEEIDKE 112
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
2-146 9.87e-13

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 61.25  E-value: 9.87e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540   2 IREAIKSDVESILSLYQILFSemalfDPERLQPAEQTREFIENAIIddkfclLVAEFNSEIKGFCiaqqqAADPYNCVVP 81
Cdd:COG3153     1 IRPATPEDAEAIAALLRAAFG-----PGREAELVDRLREDPAAGLS------LVAEDDGEIVGHV-----ALSPVDIDGE 64

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1236169540  82 RNFGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLelsVLAQNHKAIKFYEREGLTEISR 146
Cdd:COG3153    65 GPALLLGPLAVDPEYRGQGIGRALMRAALEAARERGARAV---VLLGDPSLLPFYERFGFRPAGE 126
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 49-140 1.67e-10

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 54.00  E-value: 1.67e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540  49 DKFCLLVAEFNSEIKGFCIAQQQAADPYNCVVprnfgyifDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVlaq 128
Cdd:pfam13508   1 PGGRFFVAEDDGKIVGFAALLPLDDEGALAEL--------RLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELET--- 69

                          90
                  ....*....|..
gi 1236169540 129 NHKAIKFYEREG 140
Cdd:pfam13508  70 TNRAAAFYEKLG 81
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 53-124 2.19e-09

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 50.74  E-value: 2.19e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236169540  53 LLVAEFNSEIKGFCIAQQQAADPyncvvprNFGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELS 124
Cdd:cd04301     1 FLVAEDDGEIVGFASLSPDGSGG-------DTAYIGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRLE 65
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
83-145 1.73e-08

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 49.80  E-value: 1.73e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1236169540  83 NFGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELSvlAQNHkAIKFYEREGLTEIS 145
Cdd:COG2153    57 GEAKIGRVAVLPEYRGQGLGRALMEAAIEEARERGARRIVLS--AQAH-AVGFYEKLGFVPVG 116
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
79-152 4.90e-08

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 47.60  E-value: 4.90e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1236169540  79 VVPRNFGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVLAQNHKAIKFYEREGLTEISRTMGIAL 152
Cdd:COG3393    10 AESPGVAEISGVYTHPEYRGRGLASALVAALAREALARGARTPFLYVDADNPAARRLYERLGFRPVGEYATVLF 83
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 39-146 1.91e-07

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 47.27  E-value: 1.91e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540  39 REFIENAIIDDKFC-----LLVAEFNSEIKGFcIAQqqaadpyncvvpRNFGYIFDLVVAPNFRGEKAGQKLLNAMKAWA 113
Cdd:pfam13673  14 YEFISPEALRERIDqgeyfFFVAFEGGQIVGV-IAL------------RDRGHISLLFVDPDYQGQGIGKALLEAVEDYA 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1236169540 114 KSRQLSHLELSVLAQNHkAIKFYEREGLTEISR 146
Cdd:pfam13673  81 EKDGIKLSELTVNASPY-AVPFYEKLGFRATGP 112
PRK10975 PRK10975
dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase;
33-147 2.83e-07

dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase;


Pssm-ID: 182877  Cd Length: 194  Bit Score: 47.62  E-value: 2.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540  33 QPAEQTR---EFIENAIID--DKFCLLVAEFNSEIKGFCIAQQQAAdpyncvvprNFGYIFDLVVAPNFRGEKAGQKLLN 107
Cdd:PRK10975   79 APDDSGRfyaQWIENAVRGtfDHQCLLLRDASGQIQGFVTLRELND---------TDARIGLLAVFPGAQGRGIGARLMQ 149

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1236169540 108 AMKAWAKSRQLSHLELSVLAQNHKAIKFYEREGLTeISRT 147
Cdd:PRK10975  150 AALNWCQARGLTRLRVATQMGNLAALRLYIRSGAN-IEST 188
rimI PRK09491
ribosomal-protein-alanine N-acetyltransferase; Provisional
 87-146 3.08e-06

ribosomal-protein-alanine N-acetyltransferase; Provisional


Pssm-ID: 181904 [Multi-domain]  Cd Length: 146  Bit Score: 44.15  E-value: 3.08e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236169540  87 IFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVLAQNHKAIKFYEREGLTEISR 146
Cdd:PRK09491   66 LFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAAAIALYESLGFNEVTI 125
PRK10146 PRK10146
aminoalkylphosphonate N-acetyltransferase;
85-143 2.20e-05

aminoalkylphosphonate N-acetyltransferase;


Pssm-ID: 182266 [Multi-domain]  Cd Length: 144  Bit Score: 41.83  E-value: 2.20e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1236169540  85 GYIFDLVVAPNFRGEKAGQKLLnamkAWAK--SRQLSH--LELSVLAQNHKAIKFYEREGLTE 143
Cdd:PRK10146   77 GEIQELVVMPQARGLNVGSKLL----AWAEeeARQAGAemTELSTNVKRHDAHRFYLREGYEQ 135
PRK03624 PRK03624
putative acetyltransferase; Provisional
 85-148 3.73e-04

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 38.37  E-value: 3.73e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1236169540  85 GYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLELSVLAQNHKAIKFYEREGLTEISRTM 148
Cdd:PRK03624   69 GWAYYLAVHPDFRGRGIGRALVARLEKKLIARGCPKINLQVREDNDAVLGFYEALGYEEQDRIS 132
PTZ00330 PTZ00330
acetyltransferase; Provisional
 82-148 9.41e-04

acetyltransferase; Provisional


Pssm-ID: 140351 [Multi-domain]  Cd Length: 147  Bit Score: 37.51  E-value: 9.41e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1236169540  82 RNFGYIFDLVVAPNFRGEKAGQKLLNAMKAWAKSRQLSHLelsVLAQNHKAIKFYEREGLTEISRTM 148
Cdd:PTZ00330   80 KCVGHIEDVVVDPSYRGQGLGRALISDLCEIARSSGCYKV---ILDCTEDMVAFYKKLGFRACERQM 143
PseH TIGR03585
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase; Sequences in this ...
 101-142 2.41e-03

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase; Sequences in this family are members of the pfam00583 (GNAT) superfamily of acetyltransferases and are proposed to perform a N-acetylation step in the process of pseudaminic acid biosynthesis in Campylobacter species. This gene is commonly observed in apparent operons with other genes responsible for the biosynthesis of pseudaminic acid and as a component of flagellar and exopolysaccharide biosynthesis loci. Significantly, many genomes containing other components of this pathway lack this gene, indicating that some other N-acetyl transferases may be incolved and/or the step is optional, resulting in a non-acetylated pseudaminic acid variant sugar.


Pssm-ID: 274661 [Multi-domain]  Cd Length: 152  Bit Score: 36.18  E-value: 2.41e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1236169540 101 AGQKLLNAMKAWAKSR-QLSHLELSVLAQNHKAIKFYEREGLT 142
Cdd:TIGR03585  92 VGSVLEEAALEYAFEHlGLHKLSLEVLESNNKALKLYEKFGFE 134
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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