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Conserved domains on  [gi|1239390256|ref|WP_095455094|]
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DeoR/GlpR family DNA-binding transcription regulator [Enterobacter cloacae]

Protein Classification

DeoR/GlpR family DNA-binding transcription regulator( domain architecture ID 11442564)

DeoR/GlpR family DNA-binding transcription regulator is a helix-turn-helix type transcriptional regulator that may be involved in sugar metabolism

Gene Ontology:  GO:0003700|GO:0003677
PubMed:  15808743

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 7-256 1.75e-95

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


:

Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 280.48  E-value: 1.75e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256   7 FPEQRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLQLPDAGN--FLSREQKISAEKHA 84
Cdd:COG1349     2 LAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEppFAERETLNAEEKRA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  85 IAQKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGATAAGQI 164
Cdd:COG1349    82 IARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEAL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256 165 QGIIFDQAFIGGCAMDPQMGLTGFDFADCEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVVKEALEQGVVD 244
Cdd:COG1349   162 RRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPELLE 241

                         250
                  ....*....|..
gi 1239390256 245 AFAAQDIRIVCA 256
Cdd:COG1349   242 ALEEAGVEVIVA 253
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 7-256 1.75e-95

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 280.48  E-value: 1.75e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256   7 FPEQRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLQLPDAGN--FLSREQKISAEKHA 84
Cdd:COG1349     2 LAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEppFAERETLNAEEKRA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  85 IAQKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGATAAGQI 164
Cdd:COG1349    82 IARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEAL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256 165 QGIIFDQAFIGGCAMDPQMGLTGFDFADCEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVVKEALEQGVVD 244
Cdd:COG1349   162 RRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPELLE 241

                         250
                  ....*....|..
gi 1239390256 245 AFAAQDIRIVCA 256
Cdd:COG1349   242 ALEEAGVEVIVA 253
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 79-234 2.11e-53

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 170.00  E-value: 2.11e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  79 SAEKHAIAQKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGA 158
Cdd:pfam00455   3 AEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFVGP 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1239390256 159 TAAGQIQGIIFDQAFIGGCAMDPQMGLTGFDFADCEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVV 234
Cdd:pfam00455  83 LAEEFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALIT 158
trans_reg_YciT NF040887
DNA-binding transcriptional regulator YciT; Involved in osmolarity control regulation
 11-255 2.22e-39

DNA-binding transcriptional regulator YciT; Involved in osmolarity control regulation


Pssm-ID: 468823 [Multi-domain]  Cd Length: 246  Bit Score: 136.93  E-value: 2.22e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  11 RQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLqlPDAGNFLSREQKISAEKHAIAQKAA 90
Cdd:NF040887    4 RQQQILQLVNDRGRVSVSELAQLTGVSEVTIRQDLNLLEKQSYLKRVHGSAVA--LDSDDVDTRMMTNFPLKQKLAEYAA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  91 TLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATeLLRHPLCEVIIIGGQIQRASGGSVGATAAGQIQGIIFD 170
Cdd:NF040887   82 SLVEDGETVFIEGGSTNALLARYLAERKDITIITVSHYIAH-LLKDSACEVILLGGLYQKSSESVVGPLTRLCIQQVHFS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256 171 QAFIGGCAMDPQMGLTGFDFADCEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVVKEALEQGVVDAFAAQD 250
Cdd:NF040887  161 KAFIGIDGWHPETGFTGRDMMRADVVNAVLAKGAENIVLTDSSKFGQIHPYPLGPLHQFSRVITDDGLPADYRQQLEEQG 240


                  ....*
gi 1239390256 251 IRIVC 255
Cdd:NF040887  241 IRVDL 245
srlR PRK10434
DNA-binding transcriptional repressor;
8-254 2.71e-29

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 110.93  E-value: 2.71e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256   8 PEQRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLQLPDAGNFLSREQKISAEKHA-IA 86
Cdd:PRK10434    3 PRQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKElIA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  87 QKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIII-GGQIQRASGGSVGATAAGQIQ 165
Cdd:PRK10434   83 EAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMpGGTFRKKSASFHGQLAENAFE 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256 166 GIIFDQAFIGGCAMDPQMGLTGFDFADcEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVVKEALEQGVVDA 245
Cdd:PRK10434  163 HFTFDKLFIGTDGIDLNAGVTTFNEVY-TVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDPAFRQA 241


                  ....*....
gi 1239390256 246 FAAQDIRIV 254
Cdd:PRK10434  242 LEEKGIEVI 250
AgaR NF040755
transcriptional repressor AgaR;
10-186 7.54e-27

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 104.27  E-value: 7.54e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  10 QRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLQLPDAGNF-LSREQKIS---AEKHAI 85
Cdd:NF040755    6 ERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFIPGAePSVEDKSRlntAVKRLI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  86 AQKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGATAAGQIQ 165
Cdd:NF040755   86 AAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAEQSLQ 165

                         170       180
                  ....*....|....*....|.
gi 1239390256 166 GIIFDQAFIGGCAMDPQMGLT 186
Cdd:NF040755  166 NYHFDKLFLGVDGFDLERGIT 186
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
11-63 4.06e-12

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 59.54  E-value: 4.06e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1239390256   11 RQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVL 63
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 7-256 1.75e-95

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 280.48  E-value: 1.75e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256   7 FPEQRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLQLPDAGN--FLSREQKISAEKHA 84
Cdd:COG1349     2 LAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEppFAERETLNAEEKRA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  85 IAQKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGATAAGQI 164
Cdd:COG1349    82 IARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEAL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256 165 QGIIFDQAFIGGCAMDPQMGLTGFDFADCEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVVKEALEQGVVD 244
Cdd:COG1349   162 RRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPELLE 241

                         250
                  ....*....|..
gi 1239390256 245 AFAAQDIRIVCA 256
Cdd:COG1349   242 ALEEAGVEVIVA 253
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 79-234 2.11e-53

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 170.00  E-value: 2.11e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  79 SAEKHAIAQKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGA 158
Cdd:pfam00455   3 AEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFVGP 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1239390256 159 TAAGQIQGIIFDQAFIGGCAMDPQMGLTGFDFADCEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVV 234
Cdd:pfam00455  83 LAEEFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALIT 158
trans_reg_YciT NF040887
DNA-binding transcriptional regulator YciT; Involved in osmolarity control regulation
 11-255 2.22e-39

DNA-binding transcriptional regulator YciT; Involved in osmolarity control regulation


Pssm-ID: 468823 [Multi-domain]  Cd Length: 246  Bit Score: 136.93  E-value: 2.22e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  11 RQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLqlPDAGNFLSREQKISAEKHAIAQKAA 90
Cdd:NF040887    4 RQQQILQLVNDRGRVSVSELAQLTGVSEVTIRQDLNLLEKQSYLKRVHGSAVA--LDSDDVDTRMMTNFPLKQKLAEYAA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  91 TLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATeLLRHPLCEVIIIGGQIQRASGGSVGATAAGQIQGIIFD 170
Cdd:NF040887   82 SLVEDGETVFIEGGSTNALLARYLAERKDITIITVSHYIAH-LLKDSACEVILLGGLYQKSSESVVGPLTRLCIQQVHFS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256 171 QAFIGGCAMDPQMGLTGFDFADCEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVVKEALEQGVVDAFAAQD 250
Cdd:NF040887  161 KAFIGIDGWHPETGFTGRDMMRADVVNAVLAKGAENIVLTDSSKFGQIHPYPLGPLHQFSRVITDDGLPADYRQQLEEQG 240


                  ....*
gi 1239390256 251 IRIVC 255
Cdd:NF040887  241 IRVDL 245
srlR PRK10434
DNA-binding transcriptional repressor;
8-254 2.71e-29

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 110.93  E-value: 2.71e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256   8 PEQRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLQLPDAGNFLSREQKISAEKHA-IA 86
Cdd:PRK10434    3 PRQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKElIA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  87 QKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIII-GGQIQRASGGSVGATAAGQIQ 165
Cdd:PRK10434   83 EAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMpGGTFRKKSASFHGQLAENAFE 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256 166 GIIFDQAFIGGCAMDPQMGLTGFDFADcEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVVKEALEQGVVDA 245
Cdd:PRK10434  163 HFTFDKLFIGTDGIDLNAGVTTFNEVY-TVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDPAFRQA 241


                  ....*....
gi 1239390256 246 FAAQDIRIV 254
Cdd:PRK10434  242 LEEKGIEVI 250
PRK10906 PRK10906
DeoR/GlpR family transcriptional regulator;
10-213 5.95e-27

DeoR/GlpR family transcriptional regulator;


Pssm-ID: 182827 [Multi-domain]  Cd Length: 252  Bit Score: 104.56  E-value: 5.95e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  10 QRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLqlPDAG-NFLSREQKI--SAEKHAIA 86
Cdd:PRK10906    5 QRHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGAAL--PSSSvNTPWHDRKAtqTEEKERIA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  87 QKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGATAAGQIQG 166
Cdd:PRK10906   83 RKVASQIPNGATLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATLDFISQ 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1239390256 167 IIFDQAFIGGCAMDPQMGLTGFDFADCEFKKAVIaqSNQTIVALTAD 213
Cdd:PRK10906  163 FRLDFGILGISGIDSDGSLLEFDYHEVRTKRAII--ENSRHVMLVVD 207
AgaR NF040755
transcriptional repressor AgaR;
10-186 7.54e-27

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 104.27  E-value: 7.54e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  10 QRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLQLPDAGNF-LSREQKIS---AEKHAI 85
Cdd:NF040755    6 ERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFIPGAePSVEDKSRlntAVKRLI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  86 AQKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGATAAGQIQ 165
Cdd:NF040755   86 AAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAEQSLQ 165

                         170       180
                  ....*....|....*....|.
gi 1239390256 166 GIIFDQAFIGGCAMDPQMGLT 186
Cdd:NF040755  166 NYHFDKLFLGVDGFDLERGIT 186
PRK09802 PRK09802
DeoR family transcriptional regulator;
10-238 8.38e-27

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 104.55  E-value: 8.38e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  10 QRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVLQlpdAGNFLSREQKI-------SAEK 82
Cdd:PRK09802   17 ERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALIC---DSTTPSVEPSVedksalnTAMK 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  83 HAIAQKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGATAAG 162
Cdd:PRK09802   94 RSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQ 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1239390256 163 QIQGIIFDQAFIGGCAMDPQMGLTGFDFADCEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVVKEAL 238
Cdd:PRK09802  174 SLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGI 249
PRK10681 PRK10681
DNA-binding transcriptional repressor DeoR; Provisional
 9-255 3.54e-23

DNA-binding transcriptional repressor DeoR; Provisional


Pssm-ID: 182644 [Multi-domain]  Cd Length: 252  Bit Score: 94.38  E-value: 3.54e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256   9 EQRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLhelSKEGYCKKVYGGAVLQLPDAGN--FLSREQ-KISAEKHAI 85
Cdd:PRK10681    6 DERIGQLLQALKRSDKLHLKDAAALLGVSEMTIRRDL---NAHSAPVVLLGGYIVLEPRSAShyLLSDQKsRLVEEKRRA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  86 AQKAATLVQAGGCIFIDAGTTNLALAKALPADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGATAAGQIQ 165
Cdd:PRK10681   83 AQLAATLVEPNQTLFFDCGTTTPWIIEAIDNELPFTAVCYSLNTFLALQEKPHCRAILCGGEFHASNAIFKPLDFQQTLD 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256 166 GIIFDQAFIGGCAMDPQMGLTGFDFADCEFKKAVIAQSNQTIVALTADKLPGVARFVVATCQDIDVLVVKEALEQGVVDA 245
Cdd:PRK10681  163 NICPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMAMAQKHVLVVDHSKFGKVRPARMGDLTRFDTVVSDRCPDDEFVKY 242

                         250
                  ....*....|
gi 1239390256 246 FAAQDIRIVC 255
Cdd:PRK10681  243 AQAQRIKLMY 252
PRK10411 PRK10411
L-fucose operon activator;
11-215 5.26e-21

L-fucose operon activator;


Pssm-ID: 236684 [Multi-domain]  Cd Length: 240  Bit Score: 88.32  E-value: 5.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  11 RQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGA---VLQLPDAGN-FLSREQKISAEKHAIA 86
Cdd:PRK10411    5 RQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAkyiHRQNQDSGDpFHIRLKSHYAHKADIA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  87 QKAATLVQAGGCIFIDAGTTNLALAKALPaDLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQRASGGSVGATAAGQIQG 166
Cdd:PRK10411   85 REALAWIEEGMVIALDASSTCWYLARQLP-DINIQVFTNSHPICQELGKRERIQLISSGGTLERKYGCYVNPSLISQLKS 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1239390256 167 IIFDqAFIGGC-AMDPQMGLTGFDFADCEFKKAVIAQSNQTIVALTADKL 215
Cdd:PRK10411  164 LEID-LFIFSCeGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKF 212
PRK13509 PRK13509
HTH-type transcriptional regulator UlaR;
10-150 6.64e-15

HTH-type transcriptional regulator UlaR;


Pssm-ID: 184100 [Multi-domain]  Cd Length: 251  Bit Score: 71.96  E-value: 6.64e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239390256  10 QRQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGA---VLQLPDAGNFLSREQKISAEKHAIA 86
Cdd:PRK13509    5 QRHQILLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLKKVRNGAeaiTQQRPRWTPMNIHQAQNHDEKVRIA 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1239390256  87 QKAATLVQAGGCIFIDAGTTNLALAKALpADLNVTVVTNSPAIATELLRHPLCEVIIIGGQIQR 150
Cdd:PRK13509   85 KAASQLCNPGESVVINCGSTAFLLGREL-CGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNK 147
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
11-63 4.06e-12

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 59.54  E-value: 4.06e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1239390256   11 RQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVL 63
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
HTH_DeoR pfam08220
DeoR-like helix-turn-helix domain;
11-63 5.26e-10

DeoR-like helix-turn-helix domain;


Pssm-ID: 285436 [Multi-domain]  Cd Length: 57  Bit Score: 53.80  E-value: 5.26e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1239390256  11 RQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGYCKKVYGGAVL 63
Cdd:pfam08220   1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVS 53
HTH_11 pfam08279
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.
 15-53 1.08e-04

HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.


Pssm-ID: 429896 [Multi-domain]  Cd Length: 52  Bit Score: 38.95  E-value: 1.08e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1239390256  15 IRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGY 53
Cdd:pfam08279   4 LQLLLEARGPISGQELAEKLGVSRRTIRRDIKILEELGV 42
YobV COG2378
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains ...
 11-53 2.69e-04

Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains [Transcription];


Pssm-ID: 441945 [Multi-domain]  Cd Length: 314  Bit Score: 41.60  E-value: 2.69e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1239390256  11 RQARIRQILQKSGRVVCTELASQMNVSEHTIRRDLHELSKEGY 53
Cdd:COG2378     6 RLLALLQLLQSRRGVTAAELAERLEVSERTIYRDIDALRELGV 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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