|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
2-428 |
0e+00 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 716.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 2 FLAGSIFLLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVWSIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:PRK15445 1 LLAIAIFLLTLVLVIWQPKGLGIGWSALLGAVLALLTGVVSLGDVPVVWGIVWNATLTFIAIIIISLLLDEAGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 82 HVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADIASLPLIVSNLVN 161
Cdd:PRK15445 81 HVARWAKGNGRKLFVYIVLLGAAVAALFANDGAALILTPIVLAMLLALGFSKKATLAFVMAAGFIADTASLPLVVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 162 IVSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKTPASAIKEPTTFRAGWVVLLFLLVGFFVL 241
Cdd:PRK15445 161 IVSADYFGIGFAEYASVMVPVNLVSLAASLLVLWLYFRKDIPKTYDLELLKEPASAIKDPALFKLGWIVLALLLVGYFVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 242 EPLGIPVSAIAAAGAAALFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAAT 321
Cdd:PRK15445 241 EPLGIPVSAIAGVGALILLLVARRGHAINTKKVLKGAPWQIVIFSLGMYLVVYGLRNAGLTDYLAGVLNYLADQGLFAAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 322 FGTGFLTAFLSSIMNNMPTVLIGALSIDGSAATGVIKDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWGY 401
Cdd:PRK15445 321 LGTGFLAAFLSSVMNNMPTVLIGALAIDGSNATGVIKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*..
gi 1239478782 402 YFRTGVIMTLPVLFVTLAALAWRLSVT 428
Cdd:PRK15445 401 YFKVGIIITLPVLLVTLLALALRLSLF 427
|
|
| 2a45 |
TIGR00935 |
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a ... |
2-427 |
0e+00 |
|
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a highly hydrophobic integral membrane protein involved in transport processes used to protect cells from arsenite (or antimonite). Members of the seed alignment were selected by adjacency to the ATPase subunit ArsA that energizes the transport. [Cellular processes, Detoxification, Transport and binding proteins, Other]
Pssm-ID: 213571 Cd Length: 426 Bit Score: 582.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 2 FLAGSIFLLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVWSIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:TIGR00935 1 ILAVLIFLLTLVLVIWQPKGLGIGWSATIGAVLALLSGVVSFGDVPVVTGIVWNATLTFVAIIIISLILDEIGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 82 HVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADIASLPLIVSNLVN 161
Cdd:TIGR00935 81 HMARWAKGNGRKMFIYISLLGAIVAALFANDGAALILTPIVLAMVRALGFDEAAVLPFIMASGFIADTTSLPLIVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 162 IVSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKTPASAIKEPTTFRAGWVVLLFLLVGFFVL 241
Cdd:TIGR00935 161 IVSADFFGIGFNEYAAVMIPPNIFALIASILVLYLYFRKDIPARYDVSQLREPKEAIKDQKLFKFSWVVLALLLVGYFGS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 242 EPLGIPVSAIAAAGAAALFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAAT 321
Cdd:TIGR00935 241 EFLNIPVSFVAATIALIFLVVAAKSHAVDTRKVIKGAPWNIVVFSLGMYLVVYGLRNVGLTDLLAGVLDYFADQGLFVAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 322 FGTGFLTAFLSSIMNNMPTVLIGALSIDGSAATGVIKDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWGY 401
Cdd:TIGR00935 321 MGMGFLAAFLSSIMNNMPTVLINALSIDGSNATGVMKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*.
gi 1239478782 402 YFRTGVIMTLPVLFVTLAALAWRLSV 427
Cdd:TIGR00935 401 YFKVGIVITVPVLFITLAGLYLRLSI 426
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
3-422 |
2.32e-159 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 455.96 E-value: 2.32e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 3 LAGSIFLLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVWSIVWNATAAFIAVIIISLLLDESGFFEWAALH 82
Cdd:cd01118 1 LAIAIFVLTLVLVIWRPFGLPEAVWAVLGAVIALILGLVSPHDALEVWGIVWDVTLTLIGVILLSLLLDEEGFFEWVAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 83 VSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADIASLPLIVSNLVNI 162
Cdd:cd01118 81 AARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPFLYACAFIADAASLPLPISNLVNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 163 VSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKTPASAIKEPTTFRAGWVVLLFLLVGFFVLE 242
Cdd:cd01118 161 VTAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFFRRALPKRLETASVKKPSLAIKDPLLFGLAWTLLVLLVVSAFGVD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 243 PLGIPVSAIAAAGAAALFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAATF 322
Cdd:cd01118 241 ILLIPPSFIAGVLALIFLLLARRGGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILADLLNWLVSQGLLAAIL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 323 GTGFLTAFLSSIMNNMPTVLIGALSIDGSAAtgviKDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWGYY 402
Cdd:cd01118 321 GVGLLAAFLSNVMNNLPAVLIGALALAAGHA----PEALVYANLIGVDLGPKLTPIGSLATLLWLHVLRRKGIRVSWGYY 396
|
410 420
....*....|....*....|
gi 1239478782 403 FRTGVIMTLPVLFVTLAALA 422
Cdd:cd01118 397 LKVGLIVTPPVLVVTLAALI 416
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
1-425 |
3.43e-101 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 307.44 E-value: 3.43e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 1 MFLAGSIFLLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVwsIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:COG1055 2 MILALAIFVLTYLLIILEPRGLNRAVAALLGAALLLLLGVVSLEDALEA--IDWNTILFLLGMMIIVAILDESGFFEWLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 81 LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSkgtTLAFVMAAGFIADIASLPLIVSNLV 160
Cdd:COG1055 80 IKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLN---PVPFLIAIVFAANIGGAATPIGNPT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 161 NIVSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSllKTPASAIKEPTTFRAGWVVLLFLLVGFFV 240
Cdd:COG1055 157 NIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLE--DDPKEAIKDRRLLRISLLVLALLLVGFVL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 241 LEPLGIPVSAIAAAGAAALFVVAKrghaINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAA 320
Cdd:COG1055 235 HSFLGLPPALIALLGAAVLLLLAR----VDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLA 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 321 TFGTGFLTAFLSSIMNNMPTVLIGALSIDGSAATGVIkDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWG 400
Cdd:COG1055 311 ALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNP-EPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFG 389
|
410 420
....*....|....*....|....*
gi 1239478782 401 YYFRTGVIMTLPVLFVTLAALAWRL 425
Cdd:COG1055 390 EFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB |
pfam02040 |
Arsenical pump membrane protein; |
1-418 |
3.92e-84 |
|
Arsenical pump membrane protein;
Pssm-ID: 460426 Cd Length: 423 Bit Score: 263.76 E-value: 3.92e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 1 MFLAGSIFLLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVWSIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:pfam02040 4 FIFALFIFLLILQLKILQIGNLACGGAACAGAAGALIAGDVLFHDGITVNAILAFAAIAFIAIILDNIGFDEIAAFEMAA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 81 LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADIASLPLIVSNLV 160
Cdd:pfam02040 84 AAKAKAAKGFGVRMFLGAILAAAFAAAGAALDGAAIILAMIRAAHFNAKHFFEFIIAPFFIADGFIADFTSLNFVNINLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 161 NIVSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKTPASAIKEPTTFRAGWVVLLFLLVGFFV 240
Cdd:pfam02040 164 DIFHADFFDIAFIDVAPRLFSLLAFIILASIFFLKLFFKKSDLKEVDKPEEAIKDEAIFDLNMFILGLLIIGLFAIEFFA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 241 LEPLGIPVSAIAAAGAAALFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAA 320
Cdd:pfam02040 244 IEFFSIAGSIAAGFIAAAFKIAAQHSKAVHKEAPVAEAFFAIGFFSIGMGVRNAGLRDAGLDDILAAADQAAAAGGIFAG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 321 TFGTGFLTAFLSSIMNNMPTVLIGALSIDGSAATGVIKDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWG 400
Cdd:pfam02040 324 FIAAGFIAAILNLIMNMIDALAIAALAIAGMDREALIRAALIGADLGGKDLGIGILAIGLLAHLLSHHGLKHKGGKIFKG 403
|
410
....*....|....*...
gi 1239478782 401 YYFRTGVIMTLPVLFVTL 418
Cdd:pfam02040 404 GIFKTGIILLIPLLGITI 421
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
2-428 |
0e+00 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 716.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 2 FLAGSIFLLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVWSIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:PRK15445 1 LLAIAIFLLTLVLVIWQPKGLGIGWSALLGAVLALLTGVVSLGDVPVVWGIVWNATLTFIAIIIISLLLDEAGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 82 HVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADIASLPLIVSNLVN 161
Cdd:PRK15445 81 HVARWAKGNGRKLFVYIVLLGAAVAALFANDGAALILTPIVLAMLLALGFSKKATLAFVMAAGFIADTASLPLVVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 162 IVSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKTPASAIKEPTTFRAGWVVLLFLLVGFFVL 241
Cdd:PRK15445 161 IVSADYFGIGFAEYASVMVPVNLVSLAASLLVLWLYFRKDIPKTYDLELLKEPASAIKDPALFKLGWIVLALLLVGYFVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 242 EPLGIPVSAIAAAGAAALFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAAT 321
Cdd:PRK15445 241 EPLGIPVSAIAGVGALILLLVARRGHAINTKKVLKGAPWQIVIFSLGMYLVVYGLRNAGLTDYLAGVLNYLADQGLFAAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 322 FGTGFLTAFLSSIMNNMPTVLIGALSIDGSAATGVIKDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWGY 401
Cdd:PRK15445 321 LGTGFLAAFLSSVMNNMPTVLIGALAIDGSNATGVIKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*..
gi 1239478782 402 YFRTGVIMTLPVLFVTLAALAWRLSVT 428
Cdd:PRK15445 401 YFKVGIIITLPVLLVTLLALALRLSLF 427
|
|
| 2a45 |
TIGR00935 |
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a ... |
2-427 |
0e+00 |
|
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a highly hydrophobic integral membrane protein involved in transport processes used to protect cells from arsenite (or antimonite). Members of the seed alignment were selected by adjacency to the ATPase subunit ArsA that energizes the transport. [Cellular processes, Detoxification, Transport and binding proteins, Other]
Pssm-ID: 213571 Cd Length: 426 Bit Score: 582.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 2 FLAGSIFLLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVWSIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:TIGR00935 1 ILAVLIFLLTLVLVIWQPKGLGIGWSATIGAVLALLSGVVSFGDVPVVTGIVWNATLTFVAIIIISLILDEIGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 82 HVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADIASLPLIVSNLVN 161
Cdd:TIGR00935 81 HMARWAKGNGRKMFIYISLLGAIVAALFANDGAALILTPIVLAMVRALGFDEAAVLPFIMASGFIADTTSLPLIVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 162 IVSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKTPASAIKEPTTFRAGWVVLLFLLVGFFVL 241
Cdd:TIGR00935 161 IVSADFFGIGFNEYAAVMIPPNIFALIASILVLYLYFRKDIPARYDVSQLREPKEAIKDQKLFKFSWVVLALLLVGYFGS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 242 EPLGIPVSAIAAAGAAALFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAAT 321
Cdd:TIGR00935 241 EFLNIPVSFVAATIALIFLVVAAKSHAVDTRKVIKGAPWNIVVFSLGMYLVVYGLRNVGLTDLLAGVLDYFADQGLFVAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 322 FGTGFLTAFLSSIMNNMPTVLIGALSIDGSAATGVIKDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWGY 401
Cdd:TIGR00935 321 MGMGFLAAFLSSIMNNMPTVLINALSIDGSNATGVMKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*.
gi 1239478782 402 YFRTGVIMTLPVLFVTLAALAWRLSV 427
Cdd:TIGR00935 401 YFKVGIVITVPVLFITLAGLYLRLSI 426
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
3-422 |
2.32e-159 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 455.96 E-value: 2.32e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 3 LAGSIFLLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVWSIVWNATAAFIAVIIISLLLDESGFFEWAALH 82
Cdd:cd01118 1 LAIAIFVLTLVLVIWRPFGLPEAVWAVLGAVIALILGLVSPHDALEVWGIVWDVTLTLIGVILLSLLLDEEGFFEWVAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 83 VSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADIASLPLIVSNLVNI 162
Cdd:cd01118 81 AARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPFLYACAFIADAASLPLPISNLVNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 163 VSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKTPASAIKEPTTFRAGWVVLLFLLVGFFVLE 242
Cdd:cd01118 161 VTAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFFRRALPKRLETASVKKPSLAIKDPLLFGLAWTLLVLLVVSAFGVD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 243 PLGIPVSAIAAAGAAALFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAATF 322
Cdd:cd01118 241 ILLIPPSFIAGVLALIFLLLARRGGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILADLLNWLVSQGLLAAIL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 323 GTGFLTAFLSSIMNNMPTVLIGALSIDGSAAtgviKDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWGYY 402
Cdd:cd01118 321 GVGLLAAFLSNVMNNLPAVLIGALALAAGHA----PEALVYANLIGVDLGPKLTPIGSLATLLWLHVLRRKGIRVSWGYY 396
|
410 420
....*....|....*....|
gi 1239478782 403 FRTGVIMTLPVLFVTLAALA 422
Cdd:cd01118 397 LKVGLIVTPPVLVVTLAALI 416
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
1-425 |
3.43e-101 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 307.44 E-value: 3.43e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 1 MFLAGSIFLLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVwsIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:COG1055 2 MILALAIFVLTYLLIILEPRGLNRAVAALLGAALLLLLGVVSLEDALEA--IDWNTILFLLGMMIIVAILDESGFFEWLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 81 LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSkgtTLAFVMAAGFIADIASLPLIVSNLV 160
Cdd:COG1055 80 IKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLN---PVPFLIAIVFAANIGGAATPIGNPT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 161 NIVSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSllKTPASAIKEPTTFRAGWVVLLFLLVGFFV 240
Cdd:COG1055 157 NIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLE--DDPKEAIKDRRLLRISLLVLALLLVGFVL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 241 LEPLGIPVSAIAAAGAAALFVVAKrghaINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAA 320
Cdd:COG1055 235 HSFLGLPPALIALLGAAVLLLLAR----VDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLA 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 321 TFGTGFLTAFLSSIMNNMPTVLIGALSIDGSAATGVIkDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWG 400
Cdd:COG1055 311 ALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNP-EPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFG 389
|
410 420
....*....|....*....|....*
gi 1239478782 401 YYFRTGVIMTLPVLFVTLAALAWRL 425
Cdd:COG1055 390 EFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB |
pfam02040 |
Arsenical pump membrane protein; |
1-418 |
3.92e-84 |
|
Arsenical pump membrane protein;
Pssm-ID: 460426 Cd Length: 423 Bit Score: 263.76 E-value: 3.92e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 1 MFLAGSIFLLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVWSIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:pfam02040 4 FIFALFIFLLILQLKILQIGNLACGGAACAGAAGALIAGDVLFHDGITVNAILAFAAIAFIAIILDNIGFDEIAAFEMAA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 81 LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADIASLPLIVSNLV 160
Cdd:pfam02040 84 AAKAKAAKGFGVRMFLGAILAAAFAAAGAALDGAAIILAMIRAAHFNAKHFFEFIIAPFFIADGFIADFTSLNFVNINLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 161 NIVSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKTPASAIKEPTTFRAGWVVLLFLLVGFFV 240
Cdd:pfam02040 164 DIFHADFFDIAFIDVAPRLFSLLAFIILASIFFLKLFFKKSDLKEVDKPEEAIKDEAIFDLNMFILGLLIIGLFAIEFFA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 241 LEPLGIPVSAIAAAGAAALFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAA 320
Cdd:pfam02040 244 IEFFSIAGSIAAGFIAAAFKIAAQHSKAVHKEAPVAEAFFAIGFFSIGMGVRNAGLRDAGLDDILAAADQAAAAGGIFAG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 321 TFGTGFLTAFLSSIMNNMPTVLIGALSIDGSAATGVIKDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWG 400
Cdd:pfam02040 324 FIAAGFIAAILNLIMNMIDALAIAALAIAGMDREALIRAALIGADLGGKDLGIGILAIGLLAHLLSHHGLKHKGGKIFKG 403
|
410
....*....|....*...
gi 1239478782 401 YYFRTGVIMTLPVLFVTL 418
Cdd:pfam02040 404 GIFKTGIILLIPLLGITI 421
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
14-421 |
1.08e-64 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 212.49 E-value: 1.08e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 14 MVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVVwsIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRL 93
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSA--IDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGSRRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 94 LFtWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKgtTLAFVMAAGFIADIASLPLIVSNLVNIVSADFFGLGFT 173
Cdd:cd00625 79 LL-LLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSP--PVPLLLALAFAANIGGAATPIGNPPNLIIASLSGLGFL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 174 QYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKTPASAIKEPTTFRAGWVVLLFLLVGFFVLEPLGIPVSAIAA 253
Cdd:cd00625 156 DFLAFMAPPALGLLLLLLGLLYLLFRKKLLLPDEDKLTVLAEPLPARPLLKKFLLLALLLLLLFVLLFFFLIPLGLIALL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 254 AGAAALFVVAKRghaINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAATFGTGFLTAFLSS 333
Cdd:cd00625 236 GALLLLLLLVRG---LDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALVGLPPLAALLLIGLLSALLSN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 334 IMNNMPTVLIGALSIDGSAATgvikDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWGYYFRTGVIMTLPV 413
Cdd:cd00625 313 FISNVPTVALLLPIAASLAPP----EPAWLALALGSTLGGNLTLIGSLANLIPLGAAENAGVGISFGEFLKVGLPLTLLS 388
|
....*...
gi 1239478782 414 LFVTLAAL 421
Cdd:cd00625 389 LVVSLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
12-364 |
6.62e-39 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 143.22 E-value: 6.62e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 12 LIMVIWQPrgLSIGWSASIGAVLALVTGVIHIDDIpvVWSIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRG 91
Cdd:pfam03600 1 YVLIITEK--LPRDVVALLGAVLLVLLGVLTPEEA--LSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 92 RLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSkgtTLAFVMAAGFIADIASLPLIVSNLVNIVSADFFGLG 171
Cdd:pfam03600 77 RRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLP---PSPLLIALAFAANIGGTATPIGDPPNIIIASALGLS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 172 FTQYASIMVPVNLAAIAAT-LIMLHLFFRRDIPATYDVSLLKTPAS--AIKEPTTFRAGWVVLLFLLVGFFVLEPLGIPV 248
Cdd:pfam03600 154 FGDFGFFMFPPVGVALLLVgLLPLLLIFRKLLPVRKEEEAELEELRkrAIKDKLLLAISALVLALVILGFLLLSVLALAG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 249 SAIAAAgaaalfvvakrGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLAdkGLWAATFGTGFLT 328
Cdd:pfam03600 234 ALLLLL-----------TGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGLS--GLLVALALILWLS 300
|
330 340 350
....*....|....*....|....*....|....*.
gi 1239478782 329 AFLSSIMNNMPTVLIGALSIDGSAATGVIKDAMIYA 364
Cdd:pfam03600 301 ALLSAFISNVPTAALMAPIIVGMAPAAGLGDPDPLA 336
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
8-420 |
8.55e-25 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 105.41 E-value: 8.55e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 8 FLLTLIMVIWQPRGLSIgwSASIGAVLALVTGVIHIDDIP--VVWSIVWNATAAFIAVIIISLLLDESGFFEWAALHVSR 85
Cdd:cd01116 1 FIITYALIIFEKVHRTV--AALAGALWLVILGLATLSPDLetIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 86 WGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGfskGTTLAFVMAAGFIADIASLPLIVSNLVNIVSA 165
Cdd:cd01116 79 ISKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLG---LNPVPVLISEVIAANIGGAATLIGDPPNIMIG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 166 DFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKT---PASAIKEPTTFRAGWVVLLFLLVGFFVLE 242
Cdd:cd01116 156 SAAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLALAelePKYPIKDKVLLLKSLTILTLVIIGFVLHS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 243 PLGIPVSAIAAAGAAALFVVAKRGHAINtgkVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADKGLWAATF 322
Cdd:cd01116 236 PLGVSLGWIALLGALLLLLLADKLDFED---VLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILGRIAVAVI 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 323 GTGFLTAFLSSIMNNMPTVLIGA-LSIDGSAATGVIKDAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWGY 401
Cdd:cd01116 313 LILWISALLSAFIDNIPVTATMIpIVKDLASQLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWE 392
|
410
....*....|....*....
gi 1239478782 402 YFRTGvimtLPVLFVTLAA 420
Cdd:cd01116 393 FLKVG----FPIMLVSLIL 407
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
27-421 |
1.50e-18 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 86.95 E-value: 1.50e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 27 SASIGAVLALVTGVIHIDDIPVvwSIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTwIVLLGAAVA 106
Cdd:cd01117 16 IALLGAALMLLFGVISLEDAPA--AIDLDTIILLFGLMVVSAALELSGFFDALGSRILVKAGSPRRLLFL-LVLLSGILS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 107 ALFANDGAALILTPIVIAMLLALGFSkgtTLAFVMAAGFIADIASLPLIVSNLVNIVSADFFGLGFTQYASIMVPVNLAA 186
Cdd:cd01117 93 ALLTNDTACLVFTPIVLELARVAGLP---PIPLLLALATAANIGSAATPIGNPQNLLIASESGISFPFFLAAMAPLALLG 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 187 IAATLIMLHLFFRRDIPATYDVSLLKtPASAIKEPTTFRAGWVVLLFLLVGFFVLEPLGIPVSAIAAAGAAALFVVAKRg 266
Cdd:cd01117 170 LLLLLILLLVLFPGELKGLPLDKATK-EEGVGARKLAVKLLVLILLLLVAFLALLGVIPLWTAALVAAVLLLLTRLKPR- 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 267 haintgKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNLLADkglwaaTFGTGFLTAFLSSIMNNMPTVLIgal 346
Cdd:cd01117 248 ------RVLKKVDWGLLLFFAGLFILVGGFAQGLPLEGLSRLLPLLDS------VLSLFLVSIGLSQLISNVPAVLL--- 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1239478782 347 sIDGSAATGVIKDAMIYAnvIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWGYYFRTGVIMTLPVLFVTLAAL 421
Cdd:cd01117 313 -LLPFLPSADEKDWLLLA--AGSTIAGNLTLLGSAANLIVAEAAERRGVRLSFGEFLKYGVPLTLLTAAIGILWL 384
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
61-343 |
3.55e-11 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 64.41 E-value: 3.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 61 IAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLA-- 138
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEKRSKFGsa 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 139 FVMAAGFIADIASLPLIVSNLVNIVSADFF------GLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLK 212
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAGLLeeatgiPISFFEWMLVGLPVALVGLLLLWLVLYRLLPPEIKEVPGSKEVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 213 TPASAIKEPTTFRAGWVVLLFLLVGFFVL--EPLGIPVSAIAAAGAAALFVVakrgHAINTGKVLRGAPWQIVIFSLGMY 290
Cdd:COG0471 161 REELAELGPLSRREKIALAIFALTVLLWItgSLHGIPIAVVALLGAVLLLLT----GVLTWKDAYKSIPWGVLLLFGGGL 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1239478782 291 LVVYGLRNAGLTEYLSG-VLNLLADKGLWAATFGTGFLTAFLSSIMNNMPTVLI 343
Cdd:COG0471 237 ALGAALEKTGLAAWLADaLLPLLGGLSPLLLLLLLALLTLLLTEFASNTATAAL 290
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
3-199 |
3.45e-09 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 58.24 E-value: 3.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 3 LAGSIFLLTLIMVIWQP-RGLSIGWSASIGAVLALVTGVIHIDDIpvVWSIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:COG0471 176 IALAIFALTVLLWITGSlHGIPIAVVALLGAVLLLLTGVLTWKDA--YKSIPWGVLLLFGGGLALGAALEKTGLAAWLAD 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 82 HVSRWGNGRGRLLFTWIVLLGAAVAALFANDGA-ALILTPIVIAMLLALGFSkgtTLAFVMAAGFIADIASLpLIVSNLV 160
Cdd:COG0471 254 ALLPLLGGLSPLLLLLLLALLTLLLTEFASNTAtAALLLPIAISLAQALGVN---PLPLALAVAFAASCAFL-LPVGTPP 329
|
170 180 190
....*....|....*....|....*....|....*....
gi 1239478782 161 NIVSADFFGLGFTQYASIMVPVNLAAIAATLIMLHLFFR 199
Cdd:COG0471 330 NAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLWWP 368
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
22-220 |
2.92e-05 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 46.14 E-value: 2.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 22 LSIGWSAS--IGAVLALVTGVIHIDDipVVWSIVWNATAAFIAVIIISLLLDESGFFEwaalHVSR---WGNGRGRLLFT 96
Cdd:PLN00136 31 LPIGRTAGalLSAVLMIVFHVISPDD--AYASIDLPILGLLFATMVVGSYLKNAGMFK----HLGRllaWRSQGGRDLLC 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 97 WIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGttlAFVMAAGFIADIASLPLIVSNLVNIVSADFFGLGFTQYA 176
Cdd:PLN00136 105 RVCVVTALASALFTNDTCCVVLTEFVLELAAERNLPAK---PFLLALASSANIGSSATPIGNPQNLVIAFNSKITFPKFL 181
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1239478782 177 SIMVPVNLAAIAATLIMLHLFFRRDIPATYDVSLLKTPASAIKE 220
Cdd:PLN00136 182 LGILPAMLAGMAVNMVMLLCMYWKDLDGGAELSVDGKQMEAVEE 225
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
9-343 |
4.98e-05 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 45.27 E-value: 4.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 9 LLTLIMVIWQPRGLSIGWSASIGAVLALVTGVIHIDDIPVvwSIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGN 88
Cdd:cd01115 3 ILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFS--GFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 89 GRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGttlAFVMAAGFIADIASLPLIVSNLVNIVSADFF 168
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPS---RLLMPLAFAASIGGMLTLIGTPPNLVASGYL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 169 GLGFTQYASIMVPVNLAAIAATLIMLHLFFRRDIPatydvsllktpasaikeptTFRAGWVVLLFLLVGFFVLEPLGIPV 248
Cdd:cd01115 158 ESLGGQGFSFFEFTPIGLPLLIIGLLYLWFIFRLA-------------------VLIITIVLLAALAAITGLLPVSVAIA 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 249 SAIAAAGAaalfvvakrGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSG-VLNLLADKGLWAATFGTGFL 327
Cdd:cd01115 219 IGAIVLVF---------GGVLLTKEDYKSIDWGIIFLFAGGIPLGKALESSGAAALIAEaLISLLGGLPPFAILLLLCLL 289
|
330
....*....|....*.
gi 1239478782 328 TAFLSSIMNNMPTVLI 343
Cdd:cd01115 290 TLVLTNFISNTATAVL 305
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
28-198 |
2.30e-03 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 39.88 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 28 ASIGAVLALVTGVIHIDDipVVWSIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLGAAVAA 107
Cdd:cd01115 217 IAIGAIVLVFGGVLLTKE--DYKSIDWGIIFLFAGGIPLGKALESSGAAALIAEALISLLGGLPPFAILLLLCLLTLVLT 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239478782 108 LF-ANDGAALILTPIVIAMLLALGFSKgttLAFVMAAGFIADIASLpLIVSNLVNIVSADFFGLGFTQYASIMVPVNLAA 186
Cdd:cd01115 295 NFiSNTATAVLLAPIALSIALSLGLPP---EALLLAVAIGASCAFM-LPVGTPPNAIVLGPGGYKFSDFAKVGLPLSILS 370
|
170
....*....|..
gi 1239478782 187 IAATLIMLHLFF 198
Cdd:cd01115 371 LVVSVTMIPLIW 382
|
|
| |
