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Conserved domains on  [gi|1248244047|ref|WP_096740071|]
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MULTISPECIES: TonB-dependent receptor [Pseudoalteromonas]

Protein Classification

TonB-dependent receptor( domain architecture ID 11446927)

TonB dependent receptor having a carboxypeptidase regulatory-like domain, may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0009279|GO:0055085
PubMed:  36944260|35464957
TCDB:  1.B.14

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
26-671 5.33e-94

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


:

Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 304.44  E-value: 5.33e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  26 IETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYLPALRspvlsG-AAACGGILTL 104
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIR-----GfGGGGNRVLVL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 105 EDGIPLRAAGFCNINeLFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPDTTQG-GGLVGLDYGSYGYARYKLRAG 183
Cdd:COG1629    76 VDGVPLNDPSGGDGG-LSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGkGGEVSASYGSYGTYRASLSLS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 184 QDYGNSGIGINASVTDDTGYRDDESVKQQKINIRHRFE-HSNLLLTSGLTYTNLDQHTAGFITGFESYKNEDIAQ-QNFD 261
Cdd:COG1629   155 GGNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQlGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDDgTNPY 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 262 PDAFRKARSFRAWSNAQWQ-LKNGNVLSITPYVRDQSMDFFKHFLPGTPL--------ETNSQTGIGVQSLYQHNLQSNV 332
Cdd:COG1629   235 SNDTDDNTRDRYSLSLEYEhLGDGLKLSASAYYRYDDTDLDSDFTPTPADggtleqtdFDNRTYGLELRLTYDLGFGGKH 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 333 KVNLGLDGEYTRSDFTQSQNEPTQGSAFLVATVpqgkhYDYDVNATLYAPFASVEWQLN-KWFISAGLRYEHMQYDYTNN 411
Cdd:COG1629   315 TLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSG-----ADDDGTTTSLALYAQDTYKLTdKLTLTAGLRYDYVSYDVDDT 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 412 MltgrttedgtecgfggcRYSRPASGKNSFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQREQTT---ADL 488
Cdd:COG1629   390 V-----------------TGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYSvgnPDL 452
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 489 NPEIANNAELGLKGYY--SNVSYALAVYAMSKHNTIYRDSD-------FFNVNDGSSRHRGIELEVDYALSKTLNLQFAG 559
Cdd:COG1629   453 KPETSTNYELGLRYRLldGRLSLSLALFYSDVDNEILSVPLpndsgfsTYYTNAGKARSYGVELELSYQLTPGLSLNASY 532
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 560 THAKHTYTNNqLINGLNINGNNVDTAPRNVANLDLTWQAFNNLALALQWHSVSSYYTDPEN-LHSYEGHDILSLRAKWQV 638
Cdd:COG1629   533 SYTDAKFDDD-TDGSADLDGNRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANtQGAPGGYTLVDLGAGYRF 611
                         650       660       670
                  ....*....|....*....|....*....|...
gi 1248244047 639 TNNLEVLARIINLTDEAYAERADYTSFTGDRYF 671
Cdd:COG1629   612 GDNLTLSLGVDNLFDKKYATSLSVRASNVRGFL 644
 
Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
26-671 5.33e-94

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 304.44  E-value: 5.33e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  26 IETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYLPALRspvlsG-AAACGGILTL 104
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIR-----GfGGGGNRVLVL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 105 EDGIPLRAAGFCNINeLFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPDTTQG-GGLVGLDYGSYGYARYKLRAG 183
Cdd:COG1629    76 VDGVPLNDPSGGDGG-LSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGkGGEVSASYGSYGTYRASLSLS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 184 QDYGNSGIGINASVTDDTGYRDDESVKQQKINIRHRFE-HSNLLLTSGLTYTNLDQHTAGFITGFESYKNEDIAQ-QNFD 261
Cdd:COG1629   155 GGNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQlGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDDgTNPY 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 262 PDAFRKARSFRAWSNAQWQ-LKNGNVLSITPYVRDQSMDFFKHFLPGTPL--------ETNSQTGIGVQSLYQHNLQSNV 332
Cdd:COG1629   235 SNDTDDNTRDRYSLSLEYEhLGDGLKLSASAYYRYDDTDLDSDFTPTPADggtleqtdFDNRTYGLELRLTYDLGFGGKH 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 333 KVNLGLDGEYTRSDFTQSQNEPTQGSAFLVATVpqgkhYDYDVNATLYAPFASVEWQLN-KWFISAGLRYEHMQYDYTNN 411
Cdd:COG1629   315 TLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSG-----ADDDGTTTSLALYAQDTYKLTdKLTLTAGLRYDYVSYDVDDT 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 412 MltgrttedgtecgfggcRYSRPASGKNSFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQREQTT---ADL 488
Cdd:COG1629   390 V-----------------TGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYSvgnPDL 452
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 489 NPEIANNAELGLKGYY--SNVSYALAVYAMSKHNTIYRDSD-------FFNVNDGSSRHRGIELEVDYALSKTLNLQFAG 559
Cdd:COG1629   453 KPETSTNYELGLRYRLldGRLSLSLALFYSDVDNEILSVPLpndsgfsTYYTNAGKARSYGVELELSYQLTPGLSLNASY 532
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 560 THAKHTYTNNqLINGLNINGNNVDTAPRNVANLDLTWQAFNNLALALQWHSVSSYYTDPEN-LHSYEGHDILSLRAKWQV 638
Cdd:COG1629   533 SYTDAKFDDD-TDGSADLDGNRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANtQGAPGGYTLVDLGAGYRF 611
                         650       660       670
                  ....*....|....*....|....*....|...
gi 1248244047 639 TNNLEVLARIINLTDEAYAERADYTSFTGDRYF 671
Cdd:COG1629   612 GDNLTLSLGVDNLFDKKYATSLSVRASNVRGFL 644
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
46-686 2.71e-60

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 213.47  E-value: 2.71e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  46 TISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYlpalRSPVLSGAAAcGGILTLEDGIPLRAAGFCNINELFEAH 125
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGG----STISIRGFGP-DRTLVLVDGLPLASSNYGRGVDLNTIP 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 126 SEMAQRIEVLKGPGSALYGSNAVHGVINVITPD-TTQGGGLVGLDYGSYGYAryklragqDYGNSGIGINASVTDDTG-- 202
Cdd:cd01347    76 PELIERVEVLKGPSSALYGSGAIGGVVNIITKRpTDEFGGSVTAGYGSDNSG--------SSGGGGFDVSGALADDGAfg 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 203 ------YRDDESVKQQKINIRHRFeHSNLLLTSGLTYTNLDQHTAGFITGFESYKN-EDIAQQNFDPDAFRKARSFRAWS 275
Cdd:cd01347   148 arlygaYRDGDGTIDGDGQADDSD-EERYNVAGKLDWRPDDDTRLTLDAGYQDQDAdGPGGTLPANGTGSSLGGGPSSNT 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 276 NAqWQLKNGNVLSITPYVRDQSMDFFKHFLPGTPLETNSQTGIGVQSLYQHNLQSNVKVNLGLDGEYTRSDFTQSQNEPT 355
Cdd:cd01347   227 NG-DRDWDYRDRYRKRASLGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAG 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 356 QGSAFLVATVPQ-----GKHYDYDVNATLYAPFASVEWQLN-KWFISAGLRYEHMQYDYTNNMLTGRTTedgtecgfggc 429
Cdd:cd01347   306 LNAPFGTGPVAHtltlgVEYRREELDEKQTALYAQDTIELTdDLTLTLGLRYDHYDQDSKDTIAGGTTA----------- 374
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 430 rysrpasgKNSFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQREQTTA-----DLNPEIANNAELGLKGYY 504
Cdd:cd01347   375 --------KKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAavgnpNLKPEKSKQYELGLKYDP 446
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 505 SNVSYA-LAVYAMSKHNTIYRDSD-------FFNVNDGSSRHRGIELEVDYALSKTLNLQFAGTHAKhtytNNQLINGLN 576
Cdd:cd01347   447 GDGLTLsAALFRIDIKNEIVSTPTntglglvTVYVNGGKARIRGVELEASYDLTDGLGLTGSYTYTD----TEVKRTDGA 522
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 577 INGNNVDTAPRNVANLDLTWQA-FNNLALALQWHSVSSYYTDPENL---HSYEGHDILSLRAKWQVTNNLEVLARIINLT 652
Cdd:cd01347   523 TTGNRLPGIPKHTANLGLDYELpDEGLTAGGGVRYRGKQYADTANGnntVKVPGYTLVDLSASYQFTKNLTLRLGVNNLF 602
                         650       660       670
                  ....*....|....*....|....*....|....
gi 1248244047 653 DEAYaERADYTSFTGDRYFPGKPRNAMLSATYTW 686
Cdd:cd01347   603 DKDY-YTSLSVRGSGLYGYYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
202-685 2.49e-41

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 157.24  E-value: 2.49e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 202 GYRDDESVKQQKINIRHRFEHSNLLLTSGLTYTNLDQHTAGFITGFESYKNEDiAQQNFDPDAFRKARSFRAWSNAQWQL 281
Cdd:pfam00593   1 GWQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGR-DYSDTDRKRLSLGYDYDLGDGLSWLS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 282 KNGNVLSITPYVRDQSMDFFKHFLPGTPLETNSQ-TGIGVQSLYQHNLQSNVKVNLGLDGEYTRSDFTQSQNEPTQGSAF 360
Cdd:pfam00593  80 TLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLyGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDP 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 361 LVATVPQGKHYDYDVnatlYAPFASVEWQL-NKWFISAGLRYEHMQYDYTNNMLTGRTTedgtecgfggcrysrpasgKN 439
Cdd:pfam00593 160 ANPSSSSYSDTTTDS----YGLYLQDNIKLtDRLTLTLGLRYDHYSTDGDDGNGGGDNF-------------------SR 216
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 440 SFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQREQTTA-------DLNPEIANNAELGLKGYYSNVSYALA 512
Cdd:pfam00593 217 SYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGGGGavaggnpDLKPETSDNYELGLKYDDGRLSLSLA 296
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 513 VYAMSKHNTIYRDSD--------FFNVNDGSSRHRGIELEVDYALsktlnLQFAGTHAKHTYTNNQLINGLNINGNNVDT 584
Cdd:pfam00593 297 LFYIDIKNLITSDPDgpglggtvYTYTNVGKARIRGVELELSGRL-----WGLGLSGGGYTYTDADDDADADDTGNPLPN 371
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 585 APRNVANLDLTWQAFN---NLALALQWHSVSS-YYTDPENLHSYEGHDILSLRAKWQVTNNLEVLARIINLTDEAYAERA 660
Cdd:pfam00593 372 VPRHTANLGLTYDFPLggwGARLGARYVGSGErRYGDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYY 451
                         490       500
                  ....*....|....*....|....*
gi 1248244047 661 DYTSFTGDRYfPGKPRNAMLSATYT 685
Cdd:pfam00593 452 SSGGGNLGGY-PGPGRTFYLGLSYK 475
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
43-684 2.38e-36

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 145.25  E-value: 2.38e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  43 YPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYLPALRSPVLSGAAACGGILTleDGIPLRAAGfcninELF 122
Cdd:TIGR01783   2 IPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQFGNITIRGFGLEVDIDNVYL--DGVPLLSRG-----NLA 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 123 EAHSEMAQRIEVLKGPGSALYGSNAVHGVINVIT--PDTTQGGGlVGLDYGSYGYARYKLRAGQDYGNSG-IG--INASV 197
Cdd:TIGR01783  75 IVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTkrPQDEPKGS-VTFGAGTRSGYRTAFDLGGPLGADGtFRgrLNGAR 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 198 TDDTGYRDDESVKQQKINIRHRFEHS-NLLLTSGLTYTNLDQHTAGFITGFESYKNEDIAQQNFDPDAFRKARSFRAWSN 276
Cdd:TIGR01783 154 QDGDSFYDGAGEETRLGATATDWQLDdRTLLRLGAYYQKERDRGGYGGLPASGGTSGRDLSSDRYLGTSSNRNYDDREYL 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 277 A-----QWQLKNG----NVLSITPYVRDQSMDFFKHFlpgtpleTNSQTGIGVQSLYQHNLQSNVKVNLGLDGEYTRSDF 347
Cdd:TIGR01783 234 SyglslEYQFNDVwtgkQNLRYSYFDTDSNQVQASGY-------SSDGGLFGRSLTVVNVKQDRVQIDAGLDGEFETGPI 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 348 TQ-----------------SQNEPTQGSAFLVATVPQGkhYDYDVNATLYAP----FASVEWQLN------KWFISAGLR 400
Cdd:TIGR01783 307 EHdlllgvsygqrttnrfnNTGYPSDNIYSLTATSSAR--TDIGDSPKDRALssttKALNGVALQrilladKWTLTLGGR 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 401 YEHMQYDyTNNMLTGRTTEDgtecgfggcrysrpasgknSFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQ 480
Cdd:TIGR01783 385 YDSVDVK-SNNGVAGSTGKR-------------------DDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGN 444
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 481 REQttaDLNPEIANNAELGLKGYYSNV-SYALAVYAMSKHNTIYRDS--DFFNVNDGSSRHRGIELEVDYALSKTLNLQF 557
Cdd:TIGR01783 445 SGD---ILEPEKGKNYELGVRYDLGDSlLATAALFRITKDNQLVQDPvnGTFSVNAGKTRNRGVELEARGYLTPGLSLSA 521
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 558 AGTHAKHTYTNnqlINGLNINGNNVDTAPRNVANLDLTWQAF---NNLALALQWHSVSSYYTDPENLHSYEGHDILSLRA 634
Cdd:TIGR01783 522 GYTYTDAEFTE---DTNGDTQGNTVPFVPKHTASLWASYAPPvgdNGLTLGGGVQYTGKAYVDGGNTGKVPSYTVVDLSV 598
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1248244047 635 KWQVTNNLEVLAR--IINLTDEAYAERA-DYTSFTGDryFPGKPRNAMLSATY 684
Cdd:TIGR01783 599 RYDLTKKKNLTLAlnVNNLFDRDYYTSGyRWGPSAYI--YPGAPRTVGLSVSY 649
PRK13483 PRK13483
ligand-gated channel protein;
16-654 2.17e-15

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 79.82  E-value: 2.17e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  16 AIADNKNDDAIETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQ----------RGNGQEYLP 85
Cdd:PRK13483   23 ALAQAAPDKTMETVVVTASGYEQQIRDAPASISVITREDLENRFYRDLTDALLDVPGVVVTgggdrtdislRGMGSQYTL 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  86 AL----------RSPVLSGAAACGGILTledgiPLRAAgfcninelfeahsemaQRIEVLKGPGSALYGSNAVHGVINVI 155
Cdd:PRK13483  103 ILvdgkrqssreTRPNSDGPGVEQAWTP-----PLAAI----------------ERIEVIRGPMSSLYGSDAIGGVINII 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 156 T---PDTTQGGglVGLDygsygyarYKLRAGQDYGNSGIG---INASVTDDT------GyrddESVKQQKINIRHRFE-H 222
Cdd:PRK13483  162 TrkvPNEWQGE--VRLD--------TTLQENSDSGNVYQAnffVNGPLIKDLlglqlyG----QYTQREEDDIEGGYRdK 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 223 SNLLLTSGLTYTNLDQHTAGFITGFESYKNEDIAQQNFDPDAFRKARSFRAwsnaqwqlknGNVLSITPYVRDqsmdffk 302
Cdd:PRK13483  228 DARSLTAKLALTPNEDHDIMLEVGTSNQERDSTVGKTVAPLAPGESCGRRG----------CPESSTTEYERS------- 290
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 303 HFlpgtPLETNSQTGIGVQSLYqhnLQSNVKVNLGLDGEYTRSDFTQSQNEPTqGSAFLVATVPQGKHYDY--------- 373
Cdd:PRK13483  291 TV----SLSHTGRWDFGTSDTY---IQHEEFDNKSREMKIKNTDFQSSLVAPL-GQEHTLTFGAAYNHQDLtdetsnqis 362
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 374 ---DVNATLYAPFASVEWQLNKWF-ISAGLRYEHMQydytnnmltgrttedgtecGFGGcrysrpasgknsfsNTSPK-F 448
Cdd:PRK13483  363 dltDISRTQWAVFSEDEWRIADDFaLTGGLRLDHDE-------------------NFGG--------------HVSPRvY 409
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 449 GVsYKANKNNTLYANFSRGYRAPQ----AAELYQLQREQT---TADLNPEIANNAELGLkgYYSNVSyALAVYAMSKHN- 520
Cdd:PRK13483  410 GV-WNLAPSWTVKGGVSTGFRAPSlrqtTPDWGQVSRGGNiygNPDLKPETSLNKELGL--YYDLGS-GLTASLTVFYNe 485
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 521 ------------TIYRD------SD---FFNVNDGSSrhRGIELEVDYALSKTLNLQfagthAKHTYTNNQlINGLNING 579
Cdd:PRK13483  486 fkdkitrvacpaTQCTDgpnqfgADpttYVNIDEAVT--QGVEASLSYPITSTLSLS-----GNYTYTDSE-QKSGAYKG 557
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 580 NNVDTAPRNVANLDLTWQAFNNLALALQWH-----------SVSSYYTDPenlhSYEghdILSLRAKWQVTNNLEVLARI 648
Cdd:PRK13483  558 SPLNQLPKHLFQASLNWEPTDRLNSWARVNyrgeesqpttgPSSSSFIAP----SYT---FLDLGANYQLTDNLKLSAGI 630

                  ....*.
gi 1248244047 649 INLTDE 654
Cdd:PRK13483  631 YNLFDK 636
 
Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
26-671 5.33e-94

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 304.44  E-value: 5.33e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  26 IETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYLPALRspvlsG-AAACGGILTL 104
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIR-----GfGGGGNRVLVL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 105 EDGIPLRAAGFCNINeLFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPDTTQG-GGLVGLDYGSYGYARYKLRAG 183
Cdd:COG1629    76 VDGVPLNDPSGGDGG-LSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGkGGEVSASYGSYGTYRASLSLS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 184 QDYGNSGIGINASVTDDTGYRDDESVKQQKINIRHRFE-HSNLLLTSGLTYTNLDQHTAGFITGFESYKNEDIAQ-QNFD 261
Cdd:COG1629   155 GGNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQlGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDDgTNPY 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 262 PDAFRKARSFRAWSNAQWQ-LKNGNVLSITPYVRDQSMDFFKHFLPGTPL--------ETNSQTGIGVQSLYQHNLQSNV 332
Cdd:COG1629   235 SNDTDDNTRDRYSLSLEYEhLGDGLKLSASAYYRYDDTDLDSDFTPTPADggtleqtdFDNRTYGLELRLTYDLGFGGKH 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 333 KVNLGLDGEYTRSDFTQSQNEPTQGSAFLVATVpqgkhYDYDVNATLYAPFASVEWQLN-KWFISAGLRYEHMQYDYTNN 411
Cdd:COG1629   315 TLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSG-----ADDDGTTTSLALYAQDTYKLTdKLTLTAGLRYDYVSYDVDDT 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 412 MltgrttedgtecgfggcRYSRPASGKNSFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQREQTT---ADL 488
Cdd:COG1629   390 V-----------------TGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYSvgnPDL 452
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 489 NPEIANNAELGLKGYY--SNVSYALAVYAMSKHNTIYRDSD-------FFNVNDGSSRHRGIELEVDYALSKTLNLQFAG 559
Cdd:COG1629   453 KPETSTNYELGLRYRLldGRLSLSLALFYSDVDNEILSVPLpndsgfsTYYTNAGKARSYGVELELSYQLTPGLSLNASY 532
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 560 THAKHTYTNNqLINGLNINGNNVDTAPRNVANLDLTWQAFNNLALALQWHSVSSYYTDPEN-LHSYEGHDILSLRAKWQV 638
Cdd:COG1629   533 SYTDAKFDDD-TDGSADLDGNRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANtQGAPGGYTLVDLGAGYRF 611
                         650       660       670
                  ....*....|....*....|....*....|...
gi 1248244047 639 TNNLEVLARIINLTDEAYAERADYTSFTGDRYF 671
Cdd:COG1629   612 GDNLTLSLGVDNLFDKKYATSLSVRASNVRGFL 644
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
1-686 1.25e-88

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 291.06  E-value: 1.25e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047   1 MKPYILPLLLPLSHVAIADNKNDDAIETITTTASRTEALATPYplTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNG 80
Cdd:COG4772     1 MRRALAAALLLAAAAAAEAATTLETVVVTGSRAAEARLKDVPG--SVSVVDREELENQAATSLREVLRRVPGVNVQEEDG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  81 qeylPALRsPVLS----GAAACGGILTLEDGIPLRAAGFCNINELFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVIT 156
Cdd:COG4772    79 ----FGLR-PNIGirglGPRRSRGITLLEDGIPIAPAPYGDPAAYYFPDLERMERIEVLRGAAALRYGPQTVGGAINFVT 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 157 PD-TTQGGGLVGLDYGSYGYARYKLRAGQDYGNSGIGINASVTDDTGYRDDESVKQQKINIRHRFEHS-NLLLTSGLTYT 234
Cdd:COG4772   154 RTiPTAFGGELRVTGGSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRDNSGFDINDFNAKLGYRLSdRQELTLKFQYY 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 235 NLDQHTAGFITGFESYKNediAQQNFDPDAFRKARSFRAWSNAQWQLKNGNVLSITPYVRDQSMDFFKHFLPGTPLETNS 314
Cdd:COG4772   234 DEDANTPGGLTDAQFDAD---PRQSYRPADQFDTRRTQLSLRYEHQLSDNTTLTTTAYYNDFSRNWYIRQNTADPNTPGL 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 315 QTG--------IGVQSLYQHNLQ---SNVKVNLGLDGEYTRSDFTQSQNEPTQGSAFLvatvPQGKHYDYDVNAtlYAPF 383
Cdd:COG4772   311 GLRgnprgyrsYGIEPRLTHRFElggVPHTLEVGLRYHREEEDRKQYVNTYGQGRSGA----GLRRDRRFSADA--LAAY 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 384 ASVEWQL-NKWFISAGLRYEHMQYDYTNNMLTGRTTEDgtecgfggcrysrpaSGKNSFSNTSPKFGVSYKANKNNTLYA 462
Cdd:COG4772   385 AQNRFELtGRLTLTPGLRYEHIRRDRTDRYSTRTGGDD---------------SGSNSYSEFLPGLGLLYQLTDNLQLYA 449
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 463 NFSRGYRAPQAAELyqLQREQTTADLNPEIANNAELGLKG-YYSNVSYALAVYAMSKHNTIYRDS-------DFFNVndG 534
Cdd:COG4772   450 NVSRGFEPPTFGDL--AYGNGGNPDLKPEKSWNYELGTRGrIGNGLSAEVALFYIDYDNELGSCSaaggdrsTFTNA--G 525
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 535 SSRHRGIELEVDYALSKT----LNLQFAGTHAKHTYTNNqliNGLNINGNNVDTAPRNVANLDLTWQaFNNLALALQWHS 610
Cdd:COG4772   526 ETRHQGLELALDYDLLKGgglgLPLFAAYTYTDAEFTSD---FGPVFAGNRLPYVPRHQLTAGLGYE-HGGWTANLNGRY 601
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 611 VSSYYTDPENLHSY------EGHDILSLRAKWQVTNNLEVLARIINLTDEAYAerADYTSFTGDRYFPGKPRNAMLSATY 684
Cdd:COG4772   602 VSEQFTDAANTVADgsfgkiPSYTVLDLSASYDFGKNLSLFAGVNNLFDKRYI--ASRAPNYAAGIRPGPPRTVYAGLRL 679

                  ..
gi 1248244047 685 TW 686
Cdd:COG4772   680 KF 681
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
25-644 1.48e-68

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 235.52  E-value: 1.48e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  25 AIETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQeylPALRSPVLSGAAAcGGILTL 104
Cdd:COG4771    26 ELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGGR---GGSSGISIRGLGG-DRVLVL 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 105 EDGIPLRAAGFCNINELFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPD-TTQGGGLVGLDYGSYGYARYKLRA- 182
Cdd:COG4771   102 IDGVPVNNPALGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKpTDELEGSVSLGYGSNGNGTYSGSLs 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 183 -GQDYGNSGIGINASVTDDTGYRDDESVKQQKINirhRFEHSNLLLTSGLTYTNLDQHTAGFITGFESYKNEDIA----Q 257
Cdd:COG4771   182 lGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGNS---GYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTlgdtE 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 258 QNFDPDAFRKARSFRAWSNAQWQLKNGNVLSITPYVRDQSMD--FFKHFLPGTPLETNSQTGIGVQSLYQHNLQSNVKVN 335
Cdd:COG4771   259 ISSDNAGDRDTTTDRGNYSLRYNGDLGDNLDLSLYYSRTDRDstNGSLGGSTGSFSDSDDTTYGLELDLTYPLGGNHTLT 338
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 336 LGLDGEYTRSDFTQSQNeptqgsaflvatvpqgkhyDYDVNATLYAPFASVEWQLN-KWFISAGLRYEHMQYdytnnmlt 414
Cdd:COG4771   339 LGAEYRYDDLDSSSFLG-------------------GADASRDTYGLFAQDEWKLTdKLTLTAGLRYDYYST-------- 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 415 grttedgtecgfggcrysrpaSGKNSFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQREQTTA------DL 488
Cdd:COG4771   392 ---------------------FGASNYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGTPGRyvlgnpDL 450
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 489 NPEIANNAELGLKGYYSN--VSYALAVYAMSKHNTIYRDSD-------FFNVNDGSSRHRGIELEVDYALSKTLNLQFAG 559
Cdd:COG4771   451 KPETSDNYELGLEYRLGNggLSLSLTGFYTDIKDLIVLVPVgpgpgdvLQYENVGKARTYGLELELKYRLGKGLTLTASY 530
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 560 THAKHTYTNNQlinglniNGNNVDTAPRNVANLDLTWQAFNNLALALQWHSVSSYYTDPENLHSYEGHD---ILSLRAKW 636
Cdd:COG4771   531 TYLDSKIDDGD-------TGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVTPPSGRLEGYTPgytLLDLRASY 603

                  ....*...
gi 1248244047 637 QVTNNLEV 644
Cdd:COG4771   604 KLTKNLTL 611
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
44-686 1.90e-62

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 219.75  E-value: 1.90e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  44 PLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYLpalrSPVLSGAAACGGILtlEDGIPLRAAGFcniNELFe 123
Cdd:COG4774    10 PQSVTVVTRELIEDQGATSLADALRNVPGVTFGAGEGGNGD----SFSIRGFSASGDIY--VDGLRDPGQYR---RDTF- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 124 ahseMAQRIEVLKGPGSALYGSNAVHGVINVIT--PDTTQGGGlVGLDYGSYGYARYKLRAGQDYG-NSGIGINASVTDD 200
Cdd:COG4774    80 ----NLERVEVLKGPASVLYGRGSPGGVINLVTkrPTDEPFTE-VTLTYGSDGQRRATLDVNGPLGdDLAYRLNGMYRDS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 201 TGYRDDESVKQQKINIRHRFEHS-NLLLTSGLTYTNLDQHTAGFITGFESYKNEDIAQQNF--DPDAFRKARSFRAWSNA 277
Cdd:COG4774   155 DSYRDGVDNDRWGIAPSLTWRLGdRTRLTLDYEYQDDDRTPDYGVPAVANGRPVDVDRSTFygQPDDYSDSETDSATLRL 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 278 QWQLKNGNVLSITPYVRDQSMDFFkhflPGTPLETNSQTGIGVQSLYQH----------NLQSNV-------KVNLGLDG 340
Cdd:COG4774   235 EHDFNDNWTLRNALRYSDYDRDYR----NTYPTGGNATGTVTRSAYRRDqdndtlsnqtDLTGKFdtggvkhTLLAGVEY 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 341 EYTRSDFTQSQNEPTQGSAFLVATVP-------QGKHYDYDVNATLYAPFASVEWQLN-KWFISAGLRYEHMQYDYTNNm 412
Cdd:COG4774   311 SREDSDNARYSGGGTAPTVNLYNPVYgapvtgpTLGGADNDSRTDTTGLYLQDTISLTdRWSLLAGLRYDRFDTDYTDR- 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 413 LTGRTTEDgtecgfggcrysrpasgkNSFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAelyqLQREQTTADLNPEI 492
Cdd:COG4774   390 TTGATTSS------------------YDDSAFSPRAGLVYKPTPNLSLYASYSTSFNPGGGA----PSLSNAGQALDPEK 447
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 493 ANNAELGLKgyYS----NVSYALAVYAMSKHNTIYRDSDFFN--VNDGSSRHRGIELEVDYALSKTLNLQFAGTHAKHTY 566
Cdd:COG4774   448 SRQYEVGVK--WDlldgRLSLTAALFRIEKTNVRTTDPANPGvyVQTGEQRSRGVELEATGELTPGWSVLAGYTYLDAEI 525
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 567 TNNQLINGLNINGNNVdtaPRNVANLDLTWQ-AFNNLALALQWHSVSSYYTDPENLHSYEGHDILSLRAKWQVTNNLEVL 645
Cdd:COG4774   526 TKSANAANVGNRLPNV---PRHSASLWTTYDlPLPGLTLGGGVRYVGSRYADAANTVKLPSYTRFDAGASYRLNKNLTLR 602
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|.
gi 1248244047 646 ARIINLTDEAYAEradyTSFTGDRYFPGKPRNAMLSATYTW 686
Cdd:COG4774   603 LNVNNLTDKRYYA----SAYGSGYVTPGAPRTVLLSASYRF 639
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
46-686 2.71e-60

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 213.47  E-value: 2.71e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  46 TISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYlpalRSPVLSGAAAcGGILTLEDGIPLRAAGFCNINELFEAH 125
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGG----STISIRGFGP-DRTLVLVDGLPLASSNYGRGVDLNTIP 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 126 SEMAQRIEVLKGPGSALYGSNAVHGVINVITPD-TTQGGGLVGLDYGSYGYAryklragqDYGNSGIGINASVTDDTG-- 202
Cdd:cd01347    76 PELIERVEVLKGPSSALYGSGAIGGVVNIITKRpTDEFGGSVTAGYGSDNSG--------SSGGGGFDVSGALADDGAfg 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 203 ------YRDDESVKQQKINIRHRFeHSNLLLTSGLTYTNLDQHTAGFITGFESYKN-EDIAQQNFDPDAFRKARSFRAWS 275
Cdd:cd01347   148 arlygaYRDGDGTIDGDGQADDSD-EERYNVAGKLDWRPDDDTRLTLDAGYQDQDAdGPGGTLPANGTGSSLGGGPSSNT 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 276 NAqWQLKNGNVLSITPYVRDQSMDFFKHFLPGTPLETNSQTGIGVQSLYQHNLQSNVKVNLGLDGEYTRSDFTQSQNEPT 355
Cdd:cd01347   227 NG-DRDWDYRDRYRKRASLGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAG 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 356 QGSAFLVATVPQ-----GKHYDYDVNATLYAPFASVEWQLN-KWFISAGLRYEHMQYDYTNNMLTGRTTedgtecgfggc 429
Cdd:cd01347   306 LNAPFGTGPVAHtltlgVEYRREELDEKQTALYAQDTIELTdDLTLTLGLRYDHYDQDSKDTIAGGTTA----------- 374
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 430 rysrpasgKNSFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQREQTTA-----DLNPEIANNAELGLKGYY 504
Cdd:cd01347   375 --------KKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAavgnpNLKPEKSKQYELGLKYDP 446
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 505 SNVSYA-LAVYAMSKHNTIYRDSD-------FFNVNDGSSRHRGIELEVDYALSKTLNLQFAGTHAKhtytNNQLINGLN 576
Cdd:cd01347   447 GDGLTLsAALFRIDIKNEIVSTPTntglglvTVYVNGGKARIRGVELEASYDLTDGLGLTGSYTYTD----TEVKRTDGA 522
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 577 INGNNVDTAPRNVANLDLTWQA-FNNLALALQWHSVSSYYTDPENL---HSYEGHDILSLRAKWQVTNNLEVLARIINLT 652
Cdd:cd01347   523 TTGNRLPGIPKHTANLGLDYELpDEGLTAGGGVRYRGKQYADTANGnntVKVPGYTLVDLSASYQFTKNLTLRLGVNNLF 602
                         650       660       670
                  ....*....|....*....|....*....|....
gi 1248244047 653 DEAYaERADYTSFTGDRYFPGKPRNAMLSATYTW 686
Cdd:cd01347   603 DKDY-YTSLSVRGSGLYGYYGPGRTYYLSVSYKF 635
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
28-686 4.63e-54

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 197.42  E-value: 4.63e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  28 TITTTASRTEA--LATPYplTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEY-LPALRspvlsGAAAcggILTL 104
Cdd:COG4773    50 KSSSTATKLDTplRETPQ--SVSVVTRQLIEDQGATTLDDALRNVPGVTVSSYDGGGRdSFSIR-----GFSI---DNYL 119
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 105 EDGIPLRAAGFCNINelfeahSEMAQRIEVLKGPGSALYGSNAVHGVINVIT--PDTTQGGGlVGLDYGSYGYARYKL-- 180
Cdd:COG4773   120 RDGLPLGGFGGGQPD------TANLERVEVLKGPAGLLYGAGSPGGLVNLVTkrPTAEPQGE-VSLSAGSWDTYRATAdv 192
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 181 --RAGQDyGNSGIGINASVTDDTGYRDDESVKQQ--------KINirhrfehSNLLLTSGLTYTNLDQH-TAGFITGFES 249
Cdd:COG4773   193 ggPLNED-GTLRYRLNAAYEDGDSFRDGVDNRRTliapsldwDLT-------DDTTLTLGAEYQDDDSTgDRGFLPLDGT 264
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 250 YKNEDIAQQNFDPDAFRKARSFRAWSNAQWQLKNGNVLSITPYVRDQSMDFFKHFLPGTPLETNS----QTGIGVQSLYQ 325
Cdd:COG4773   265 LLDLPRSTNLGEPWDYYDTETTTLFAELEHRFNDDWSLRANARYSDSDRDGRSAYAYGAPDAATGtltrYASARDGDSRS 344
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 326 HNLQSNV-----------KVNLGLDGEYTRSDFTQSQNEPT--QGSAFLVATVPQGKHYDYDVNATLYAPFASVEWQLN- 391
Cdd:COG4773   345 DSLDANLngkfetgglehTLLVGADYSRYDSDSDSATAGTIniYNPVYGNLPEPDFDASDTDTTTRQTGLYAQDQISLTd 424
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 392 KWFISAGLRYEHMQYDYTNNMLTGRTTEDGTEcgfggcrysrpasgknsfsnTSPKFGVSYKANKNNTLYANFSRGYRaP 471
Cdd:COG4773   425 RLSLLLGGRYDWYETDSTNRLGGSTTSYDDSA--------------------FTPRAGLVYDLTPGLSLYASYSESFE-P 483
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 472 QAAelyqlqREQTTADLNPEIANNAELGLKGYYSN--VSYALAVYAMSKHNTIYRDSD--FFNVNDGSSRHRGIELEVDY 547
Cdd:COG4773   484 QSG------ADNNGNPLDPETGKQYEAGVKGELFDgrLNATLAVFDITQKNVATTDPDnpNFYVQVGEVRSRGVELELSG 557
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 548 ALSKTLNLQFAGTHAKHTYTNNqlinGLNINGNNVDTAPRNVANL----DLTWQAFNNLALALQWHSVSSYYTDPENLHS 623
Cdd:COG4773   558 ELTPGLNLIAGYTYTDAKITKD----ADALEGKRLTNVPRHTASLwttyRFPSGALKGLGLGGGVRYVGERYGDAANTFT 633
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1248244047 624 YEGHDILSLRAKWQVTNNLEVLARIINLTDEAYAEradyTSFTGDRYFPGKPRNAMLSATYTW 686
Cdd:COG4773   634 LPSYTLVDAGARYDLGKNWTLQLNVNNLFDKKYYA----SSGSRGYVYYGAPRNVRLSLSYKF 692
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
202-685 2.49e-41

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 157.24  E-value: 2.49e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 202 GYRDDESVKQQKINIRHRFEHSNLLLTSGLTYTNLDQHTAGFITGFESYKNEDiAQQNFDPDAFRKARSFRAWSNAQWQL 281
Cdd:pfam00593   1 GWQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGR-DYSDTDRKRLSLGYDYDLGDGLSWLS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 282 KNGNVLSITPYVRDQSMDFFKHFLPGTPLETNSQ-TGIGVQSLYQHNLQSNVKVNLGLDGEYTRSDFTQSQNEPTQGSAF 360
Cdd:pfam00593  80 TLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLyGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDP 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 361 LVATVPQGKHYDYDVnatlYAPFASVEWQL-NKWFISAGLRYEHMQYDYTNNMLTGRTTedgtecgfggcrysrpasgKN 439
Cdd:pfam00593 160 ANPSSSSYSDTTTDS----YGLYLQDNIKLtDRLTLTLGLRYDHYSTDGDDGNGGGDNF-------------------SR 216
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 440 SFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQREQTTA-------DLNPEIANNAELGLKGYYSNVSYALA 512
Cdd:pfam00593 217 SYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGGGGavaggnpDLKPETSDNYELGLKYDDGRLSLSLA 296
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 513 VYAMSKHNTIYRDSD--------FFNVNDGSSRHRGIELEVDYALsktlnLQFAGTHAKHTYTNNQLINGLNINGNNVDT 584
Cdd:pfam00593 297 LFYIDIKNLITSDPDgpglggtvYTYTNVGKARIRGVELELSGRL-----WGLGLSGGGYTYTDADDDADADDTGNPLPN 371
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 585 APRNVANLDLTWQAFN---NLALALQWHSVSS-YYTDPENLHSYEGHDILSLRAKWQVTNNLEVLARIINLTDEAYAERA 660
Cdd:pfam00593 372 VPRHTANLGLTYDFPLggwGARLGARYVGSGErRYGDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYY 451
                         490       500
                  ....*....|....*....|....*
gi 1248244047 661 DYTSFTGDRYfPGKPRNAMLSATYT 685
Cdd:pfam00593 452 SSGGGNLGGY-PGPGRTFYLGLSYK 475
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
43-684 2.38e-36

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 145.25  E-value: 2.38e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  43 YPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYLPALRSPVLSGAAACGGILTleDGIPLRAAGfcninELF 122
Cdd:TIGR01783   2 IPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQFGNITIRGFGLEVDIDNVYL--DGVPLLSRG-----NLA 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 123 EAHSEMAQRIEVLKGPGSALYGSNAVHGVINVIT--PDTTQGGGlVGLDYGSYGYARYKLRAGQDYGNSG-IG--INASV 197
Cdd:TIGR01783  75 IVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTkrPQDEPKGS-VTFGAGTRSGYRTAFDLGGPLGADGtFRgrLNGAR 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 198 TDDTGYRDDESVKQQKINIRHRFEHS-NLLLTSGLTYTNLDQHTAGFITGFESYKNEDIAQQNFDPDAFRKARSFRAWSN 276
Cdd:TIGR01783 154 QDGDSFYDGAGEETRLGATATDWQLDdRTLLRLGAYYQKERDRGGYGGLPASGGTSGRDLSSDRYLGTSSNRNYDDREYL 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 277 A-----QWQLKNG----NVLSITPYVRDQSMDFFKHFlpgtpleTNSQTGIGVQSLYQHNLQSNVKVNLGLDGEYTRSDF 347
Cdd:TIGR01783 234 SyglslEYQFNDVwtgkQNLRYSYFDTDSNQVQASGY-------SSDGGLFGRSLTVVNVKQDRVQIDAGLDGEFETGPI 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 348 TQ-----------------SQNEPTQGSAFLVATVPQGkhYDYDVNATLYAP----FASVEWQLN------KWFISAGLR 400
Cdd:TIGR01783 307 EHdlllgvsygqrttnrfnNTGYPSDNIYSLTATSSAR--TDIGDSPKDRALssttKALNGVALQrilladKWTLTLGGR 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 401 YEHMQYDyTNNMLTGRTTEDgtecgfggcrysrpasgknSFSNTSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQ 480
Cdd:TIGR01783 385 YDSVDVK-SNNGVAGSTGKR-------------------DDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGN 444
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 481 REQttaDLNPEIANNAELGLKGYYSNV-SYALAVYAMSKHNTIYRDS--DFFNVNDGSSRHRGIELEVDYALSKTLNLQF 557
Cdd:TIGR01783 445 SGD---ILEPEKGKNYELGVRYDLGDSlLATAALFRITKDNQLVQDPvnGTFSVNAGKTRNRGVELEARGYLTPGLSLSA 521
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 558 AGTHAKHTYTNnqlINGLNINGNNVDTAPRNVANLDLTWQAF---NNLALALQWHSVSSYYTDPENLHSYEGHDILSLRA 634
Cdd:TIGR01783 522 GYTYTDAEFTE---DTNGDTQGNTVPFVPKHTASLWASYAPPvgdNGLTLGGGVQYTGKAYVDGGNTGKVPSYTVVDLSV 598
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1248244047 635 KWQVTNNLEVLAR--IINLTDEAYAERA-DYTSFTGDryFPGKPRNAMLSATY 684
Cdd:TIGR01783 599 RYDLTKKKNLTLAlnVNNLFDRDYYTSGyRWGPSAYI--YPGAPRTVGLSVSY 649
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
27-686 1.45e-30

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 127.89  E-value: 1.45e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  27 ETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANV---QRGNGQeylpalrSPVLSGAAAcGGILT 103
Cdd:TIGR01785   2 DTVTVTATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTVPGVDVtggGRPPGQ-------SINIRGLQD-NRVLV 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 104 LEDGIPLRAAGFCNINELFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPDTT-------QGGGLVGLDYGSYGYA 176
Cdd:TIGR01785  74 VVDGARQNYQRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAAdllrpgqLFGGLAKLSYGSNNNS 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 177 RykLRAGQDYGNSGIGINASVTDdtGYRDDESVKQ-QKINIRHRFEHSNLLLTSGLTYTNLDQHTAgfITGFESYKNEDI 255
Cdd:TIGR01785 154 F--GGSVAVAGRLDDNLDALVAA--TYRDGGNYRNgNKEEATNSAYVQKNLLAKLGWQLDDAQRLE--FSYFTTEGSLDE 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 256 AQQNFDPDAF----------RKARSFRAWSNAQWQLKNGNVLS--ITPYVRDQSMDffkHFLPGTPLETNSQT-----GI 318
Cdd:TIGR01785 228 AQNSGPGTEYvlgssstllaSSTRDRSATLTYNWTPEDNPWLDatASLYYNRTEND---NDRSARGVGREEGYqyttyGA 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 319 GVQSLYQHNLQSNVKVNLGLDGEYTRsdftqsqnepTQGSAFLVATVPQGKHYDYDVNATLYAPFASVEWQL--NKWFIS 396
Cdd:TIGR01785 305 TLQNTSRFDVASWSTLTYGVDWMKDK----------RRTESFDPNSVTTIVPNPPSAKEYFFGLFLQDNIPLldDRLTLS 374
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 397 AGLRYEHMQYDytnnmltGRTTEDgtecgfggcrYSRPASGKNSFsntSPKFGVSYKANKNNTLYANFSRGYRAPQAAEL 476
Cdd:TIGR01785 375 AGLRYDHYKLS-------PKTTAD----------TEAVDRSYSRW---SPSLGLSYKPVDWLTLYASYSQGFRAPSIDEL 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 477 YQLQREQTTA---------DLNPEIANNAELGLKGYYSNVSYA---LAVYAMSKHNtiyRDSDFFN-------------- 530
Cdd:TIGR01785 435 YGTGDHPGTPggytfapnpNLKPETSKTWELGANLSFDNLLLDndqLQFKVAYFYN---DVKDFIDltigvtdnvtagmn 511
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 531 -----VNDGSSRHRGIELEVDYALSKtLNLQFAGTHAKHTYTN-NQlinglningnNVDTAPRNVANLDLTWQAFN-NLA 603
Cdd:TIGR01785 512 nitqyVNIDGARIRGIEASASYDAGL-WATGLSYGYTIGKDQNtNQ----------WLSNIPPLKLVVTVGYRFPDrRLD 580
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 604 LALQWHSVSSYYTDPE-------NLHSYEGHDILSLRAKWQVTNNLEVLAR--IINLTDEAYAERADY-TSFTGdryfpg 673
Cdd:TIGR01785 581 LGAKAAYYERQSESPTtedvaanGLLTTPGYTVVDLYATYQPNAVKGLTVRfgVNNLTDRKYTPAQSVpGAGPG------ 654
                         730
                  ....*....|...
gi 1248244047 674 kpRNAMLSATYTW 686
Cdd:TIGR01785 655 --RNFKGSVKYQF 665
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
29-316 2.08e-28

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 114.97  E-value: 2.08e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  29 ITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQR--GNGQEYLPALRspvlsGAAAcGGILTLED 106
Cdd:COG4206     1 VVVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALRRVPGVQVSSsgGPGSAASISIR-----GLGS-NQTLVLID 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 107 GIPLRAA--GFCNINELfeaHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPDTTQGGGL-VGLDYGSYGYARYKLRAG 183
Cdd:COG4206    75 GVPLNDPslGGVDLSLI---PPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGsVSASYGSFGTRRLSASLS 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 184 QDYGNSGIGINASVTDDTGYRDDESVKQQKINIRhrfehsNLLLTSGLTYTNLDQHTAGFITGFESYKNediaqqNFDPD 263
Cdd:COG4206   152 GGAGKFSYSLSASYRRSDGYRYNDPDLRNNDGYE------NTSLNARLGYKLGDNGSLSLSGGYSDSER------GYPGA 219
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1248244047 264 AFRkARSFRAWSNAQWQLKNGNVLSITPYVRDQSMDFFKHFLPGTPLETNSQT 316
Cdd:COG4206   220 VGS-DRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGAR 271
TonB-B12 TIGR01779
TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane ...
25-685 1.94e-24

TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane receptor found in gamma proteobacteria responsible for translocating the cobalt-containing vitamin B12 (cobalamin). [Transport and binding proteins, Other, Transport and binding proteins, Porins]


Pssm-ID: 273802 [Multi-domain]  Cd Length: 614  Bit Score: 108.41  E-value: 1.94e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  25 AIETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYLPALrspVLSGAAAcGGILTL 104
Cdd:TIGR01779  27 PLDTVVVTANRFAQTASQTLAPVTIITRQDIERTQAKSLPELLRRLPGVSIAQNGGRGQNTSL---FLRGTES-DHVLVL 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 105 EDGIPL--RAAGFCNINELfeaHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPDTTQGGG-LVGLDYGSYGYARYKLR 181
Cdd:TIGR01779 103 IDGIRFgsAAAGAADFQQL---PVELVERIEYVRGPRSSLYGSEAIGGVINIITRRRSGGQGtTLSAGLGSLDYQEYSIA 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 182 AGQDYGNSG-IGINASVTDDTGYRDDESVKQQKINIRHRFEHSNLLLTSGLTYtnlDQHTAGFITGFeSYKNediaQQNF 260
Cdd:TIGR01779 180 SGVAIGENGwYSVALGTESTKGINVRPGGPGVYDPDRDGFRSDSLLLGGGHRF---DESWSLFVNAL-RYEN----RNDY 251
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 261 DPDAFrkarsfrawsnaqwqlknGNVLSITPYVRDQSMDFFKHFL-PGTPLETNSQTGigvqslyqhnlQSNVKVNLGLD 339
Cdd:TIGR01779 252 DNYSF------------------GTRLYKEAEKGDQSFTGGRQRQsERDVSELTLSTG-----------KSKDWDYAYSK 302
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 340 GEY-TRSDF-----TQSQNEPTQGSAFLVA---------TVPQGKHYDYDVNATlyAPFASVEWQLNKWFISAGLRYEhm 404
Cdd:TIGR01779 303 GRYsSTSDTreqrnIQWQNDLLVGDGWVLAggvdwqkdsIISSTADKEDDRSNT--AAFAQVLQQWGQQLLEASLRRD-- 378
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 405 qydytNNMLTGRTTEDGTECGFggcrysrpasgknsfsNTSPKFGVSykanknntlyANFSRGYRAPQAAELYqlQREQT 484
Cdd:TIGR01779 379 -----DNQQFGSHTTGSIAWGY----------------QFIEELRFT----------ASYGTAFKAPNLNQLY--YPSYG 425
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 485 TADLNPEIANNAELGLKGYYSNVSYALAVYAMSKHNTIYRDSDFFNV--NDGSSRHRGIELevdyalskTLNLQFAG-TH 561
Cdd:TIGR01779 426 NPNLQPETSKSAELGFYGLFSGGKWSISGYRTKINDLIDYDSHPKGYpnNIGEARIKGVEA--------TAEFATGGwTH 497
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 562 -AKHTYTNNQLINGLningnnvDTAPR---NVANLDLTWqAFNNLALALQWHSVSSYYTDPENLHSYE-----GHDILSL 632
Cdd:TIGR01779 498 qLSVDLLDAQNVNTG-------NTLPRrarQMYKWNADR-AFEQFDWGASYQYVGKRYDDDYNTYPTQnvrlgGYSLLDL 569
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1248244047 633 RAKWQVTNNLEVLARIINLTDEAYaERAdytsftgdRYFPGKPRNAMLSATYT 685
Cdd:TIGR01779 570 RVSYYVTDSWTVQGRIANLFDKDY-ETA--------YGYPQAGRAYYLSIRYQ 613
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
27-686 1.43e-20

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 96.71  E-value: 1.43e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  27 ETITTTASRTEALA----TPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANV---QRGNGQEYlpALRSpvLSGAaacg 99
Cdd:TIGR01786   1 DTITVTATRTADPQrrdlSVTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVvegGRGGSQGI--NIRG--LDKN---- 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 100 GILTLEDGIPL------RAAGFCNINELfeaHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPDTT-------QGGGLV 166
Cdd:TIGR01786  73 RVAVLVDGIRQntsyggQGSTFYAINSI---DPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAAdllkpgkDLGGLS 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 167 GLDYGS-----------------------YGYARYK-LRAGqDYGNSGIGINASVTDDTGYRDdESVK---QQKINIRHR 219
Cdd:TIGR01786 150 KLGYSSannrftqsvaaagrnddvdalvqATYRRGHeLKNG-NKANIGNESKRSKPNPSDYKS-QSFLaklGWQLNDAHR 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 220 FEHSnllltsgLTYTNLDQHTAGFITGfESYKNEDIAQQNFDPDAFRKARSFRAWSNAQWQLKNGNVL-----------S 288
Cdd:TIGR01786 228 LGLS-------LEYTQTDYDEPEMTNT-SYLTKPLGAPLLSSTVVLGDSKTRDRRTGLDYELNPDNSWldtvklaldkqY 299
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 289 ITPYVRDQSMDFFKHflPGTPLETNSQTGIGVQ----SLYQHNLQSNVKVNLGLDGEYTRSDFTQS---QNEPTQGSAFL 361
Cdd:TIGR01786 300 IQLYNYLNATSASDY--PGVDKNGRYKDKYDYYtlgfDTNNKIEFSVHSLSLTYGLDRFKDKVSTGdsrRNLPTAAYNLY 377
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 362 VATVPQGKhydydVNATLYAPFASVEWQLNKWF-ISAGLRYEHMQYDYTNNMLTGRTTEDGTECGFggcrysrpasgkns 440
Cdd:TIGR01786 378 GYEGENRP-----VKGSNFGLFLQDNIKLGDWLsLSAGLRYDHYKTDPKADESKDYGAISKTYSRW-------------- 438
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 441 fsntSPKFGVSYKANKNNTLYANFSRGYRAPQAAELYQLQREQTTA--------DLNPEIANNAELGLKG---------- 502
Cdd:TIGR01786 439 ----SPSLGLTYKPTPWLTLYYSYSQGFRAPSFDELYGTGAHPGGGpytflpnpNLKPETSKNWEIGINLhfdqldfkvs 514
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 503 -YYSNVS--YALAVYAMSKHN-TIYRDSDFFN-VNDGSSRHRGIELEVDY------ALSKTLNLQFAGTHAKHTYTNNQL 571
Cdd:TIGR01786 515 yFRNDYKdfIDLGIGVTAKGNmAQVGSNTITNyVNIDNARIRGIELSGRYdlgsffSGPDGWTTTLKYGYTKGKDSDTNP 594
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 572 INGLNINGNNVDT----APRNVANLDLTWQAFN-NLALALQWHSVSSYYTDPENLHSYEGHDILSLRAKWQVTNNLEVLA 646
Cdd:TIGR01786 595 WLNAITPLKVVLGlgydHPDEKWGVGLTLTFSGaKDAVDAYATYYENGEAAKAGPLRTPSYTVVDLYGYYKPNKNLTLRF 674
                         730       740       750       760
                  ....*....|....*....|....*....|....*....|.
gi 1248244047 647 RIINLTDEAYAERAD-YTSFTGDRYFPGKPRNAMLSATYTW 686
Cdd:TIGR01786 675 GVYNLLDRKYTTWESaRQAGPLATGYTAPGRNYKASVEYKF 715
PRK13483 PRK13483
ligand-gated channel protein;
16-654 2.17e-15

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 79.82  E-value: 2.17e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  16 AIADNKNDDAIETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQ----------RGNGQEYLP 85
Cdd:PRK13483   23 ALAQAAPDKTMETVVVTASGYEQQIRDAPASISVITREDLENRFYRDLTDALLDVPGVVVTgggdrtdislRGMGSQYTL 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  86 AL----------RSPVLSGAAACGGILTledgiPLRAAgfcninelfeahsemaQRIEVLKGPGSALYGSNAVHGVINVI 155
Cdd:PRK13483  103 ILvdgkrqssreTRPNSDGPGVEQAWTP-----PLAAI----------------ERIEVIRGPMSSLYGSDAIGGVINII 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 156 T---PDTTQGGglVGLDygsygyarYKLRAGQDYGNSGIG---INASVTDDT------GyrddESVKQQKINIRHRFE-H 222
Cdd:PRK13483  162 TrkvPNEWQGE--VRLD--------TTLQENSDSGNVYQAnffVNGPLIKDLlglqlyG----QYTQREEDDIEGGYRdK 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 223 SNLLLTSGLTYTNLDQHTAGFITGFESYKNEDIAQQNFDPDAFRKARSFRAwsnaqwqlknGNVLSITPYVRDqsmdffk 302
Cdd:PRK13483  228 DARSLTAKLALTPNEDHDIMLEVGTSNQERDSTVGKTVAPLAPGESCGRRG----------CPESSTTEYERS------- 290
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 303 HFlpgtPLETNSQTGIGVQSLYqhnLQSNVKVNLGLDGEYTRSDFTQSQNEPTqGSAFLVATVPQGKHYDY--------- 373
Cdd:PRK13483  291 TV----SLSHTGRWDFGTSDTY---IQHEEFDNKSREMKIKNTDFQSSLVAPL-GQEHTLTFGAAYNHQDLtdetsnqis 362
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 374 ---DVNATLYAPFASVEWQLNKWF-ISAGLRYEHMQydytnnmltgrttedgtecGFGGcrysrpasgknsfsNTSPK-F 448
Cdd:PRK13483  363 dltDISRTQWAVFSEDEWRIADDFaLTGGLRLDHDE-------------------NFGG--------------HVSPRvY 409
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 449 GVsYKANKNNTLYANFSRGYRAPQ----AAELYQLQREQT---TADLNPEIANNAELGLkgYYSNVSyALAVYAMSKHN- 520
Cdd:PRK13483  410 GV-WNLAPSWTVKGGVSTGFRAPSlrqtTPDWGQVSRGGNiygNPDLKPETSLNKELGL--YYDLGS-GLTASLTVFYNe 485
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 521 ------------TIYRD------SD---FFNVNDGSSrhRGIELEVDYALSKTLNLQfagthAKHTYTNNQlINGLNING 579
Cdd:PRK13483  486 fkdkitrvacpaTQCTDgpnqfgADpttYVNIDEAVT--QGVEASLSYPITSTLSLS-----GNYTYTDSE-QKSGAYKG 557
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 580 NNVDTAPRNVANLDLTWQAFNNLALALQWH-----------SVSSYYTDPenlhSYEghdILSLRAKWQVTNNLEVLARI 648
Cdd:PRK13483  558 SPLNQLPKHLFQASLNWEPTDRLNSWARVNyrgeesqpttgPSSSSFIAP----SYT---FLDLGANYQLTDNLKLSAGI 630

                  ....*.
gi 1248244047 649 INLTDE 654
Cdd:PRK13483  631 YNLFDK 636
PRK13486 PRK13486
TonB-dependent receptor;
24-670 6.63e-15

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 78.52  E-value: 6.63e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  24 DAIETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQ--------EYLPALRSPVLSGA 95
Cdd:PRK13486   23 AAEDVMIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRSVEGVDVESGTGKtggleisiRGMPASYTLILIDG 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  96 AACGGIltlEDGIPlraAGFCNINELFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPDTTQggglvglDYGSYGY 175
Cdd:PRK13486  103 VRQGGS---SDVTP---NGFSAMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNAD-------KWLSSVN 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 176 ARYKLRAGQDYGNSGI------------GINASVTDDTGYRDDESV---------------KQQKINIRHRFE----HSN 224
Cdd:PRK13486  170 AGLNLQESNKWGNSSQfnfwssgplvddSVSLQVRGSTQQRQGSSVtslsdtaatripyptESQNYNLGARLDwkasEQD 249
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 225 LLL----TSGLTYTNLDQHTAGFITGFES---YKNEDIAQqnfdpdAFRKARSFRAW-SNAQW-QLKN-GNVLSITPYVR 294
Cdd:PRK13486  250 VLWfdmdTTRQRYDNRDGQLGSLTGGYDRtlrYERNKISA------GYDHTFTFGTWkSYLNWnETENkGRELVRSVLKR 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 295 DQSmdffkhFLPGTPLETNsQTGIGVQSLYQHNLQSNVKVNLGldGEYTRSDFTQSQNEPTQGSAFLVATvpqgkhydyd 374
Cdd:PRK13486  324 DKW------GLAGQPRELK-ESNLILNSLLLTPLGESHLVTVG--GEFQSSSMKDGVVLASTGETFRQKS---------- 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 375 vnatlYAPFASVEWQLNKWF-ISAGLRYEHMQYdytnnmltgrttedgtecgFGGcrysrpasgknsfsNTSPKFGVSYK 453
Cdd:PRK13486  385 -----WSVFAEDEWHLTDALaLTAGSRYEHHEQ-------------------FGG--------------HFSPRAYLVWD 426
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 454 ANKNNTLYANFSRGYRAPQAAELYQ----LQREQTT-----ADLNPEIANNAELGL------------KGYYSNVSYALA 512
Cdd:PRK13486  427 VADAWTLKGGVTTGYKAPRMGQLHKgisgVSGQGKTnllgnPDLKPEESVSYEAGVyydnpaglnanvTGFMTDFSNKIV 506
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 513 VYAMSKHNTIYrdsdffnVNDGSSRHRGIELEVDYAL---SKTLNLQFAGTHAKHTYTNNQlinglninGNNVDTAPRNV 589
Cdd:PRK13486  507 SYSINDNTNSY-------VNSGKARLHGVEFAGTLPLwseDVTLSLNYTWTRSEQRDGDNK--------GAPLSYTPEHM 571
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 590 ANLDLTWQAFNNLALAL-------------QWHSVSS-----YYTDPENLHSYEghdILSLRAKWQVTNNLEVLARIINL 651
Cdd:PRK13486  572 VNAKLNWQITEEVASWLgaryrgktprftqNYSSLSAvqkkvYDEKGEYLKAWT---VVDAGLSWKMTDALTLNAAVNNL 648
                         730
                  ....*....|....*....
gi 1248244047 652 TDEAYAERADYTSFTGDRY 670
Cdd:PRK13486  649 LNKDYSDVSLYSAGKSTLY 667
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
44-151 1.76e-13

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 66.91  E-value: 1.76e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  44 PLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYlpalRSPVLSGAAAcGGILTLEDGIPLRAAGFcNINELFE 123
Cdd:pfam07715   6 PGSVSVVTAEDIEDQGATNLADALRGVPGVSVSSGGGGGG----SSISIRGFGS-NRVLVLVDGVPLNSGGG-GSVDLNS 79
                          90       100
                  ....*....|....*....|....*...
gi 1248244047 124 AHSEMAQRIEVLKGPGSALYGSNAVHGV 151
Cdd:pfam07715  80 IDPEDIERVEVLKGPASALYGSGAIGGV 107
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
22-656 9.52e-12

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 68.10  E-value: 9.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  22 NDDAIETITTTASRTE-----ALAtpyPLTISTLSEA---QLNSIApthveESLQRIAGANVQR--GNGQeylpaLRSPV 91
Cdd:PRK10641   21 QDTSPDTLVVTANRFQqpvstVLA---PTTVVTRDDIdrwQSKSVN-----DVLRRLPGVDIAQngGLGQ-----LSSLF 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  92 LSGAAAcGGILTLEDGIPLRAAGFCNINELFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPDTTQGGGLvgldyg 171
Cdd:PRK10641   88 IRGTNS-SHVLVLIDGVRLNQAGISGSADLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDKPGTTL------ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 172 sygyaryklragqdygNSGIGINasvtddtGYRDDESVKQQKINirhrfEHSNLLLTSGLTYTNldqhtagfitGFESYK 251
Cdd:PRK10641  161 ----------------SAGWGSN-------GYQNYDGSTQQQLG-----DNTRVTLAGDYTYTK----------GFDVVA 202
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 252 NEDIAQQNF-DPDAFRkARSFraWSNAQWQLKNgnvlSITPYVR----DQSMDFFKHFLPGTPLETNSQtgigvqsLYQH 326
Cdd:PRK10641  203 YGNTGTQAQpDRDGFM-SKTL--WGGLEHQFND----QWSGFVRgygyDNRTDYDAYYSPGSPLIDTRQ-------LYSQ 268
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 327 NLQSNVKVNlgldgeytrSDFTQSQneptqgsafLVATVPQGKHYDYDVNATLYAPFAS--------VEW----QLNKWF 394
Cdd:PRK10641  269 SWDAGLRYN---------GGIYSSQ---------LIASYSHSKDYNYDPHYGRYDSSATlddmkqynVQWgntvQVGHGN 330
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 395 ISAGLRYEHMQYDYTNNMLTGRTTEDGTECGFGGCRYSRP----ASGKnsfSNTSPKFG--------VSYKANKNNTLYA 462
Cdd:PRK10641  331 ISAGVDWQKQTTTPGTGYVPDGYDQRNTGIYLTGQQQIGDvtleGAAR---SDDNSQFGwhgtwqtsAGWEFIDGYRFIA 407
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 463 NFSRGYRAPQAAELYQLqreQTTADLNPEIANNAELGLKGYYSNVSYALAVYAMSKHNTI-YRDSDFFNVNDGSSRHRGI 541
Cdd:PRK10641  408 SYGTAFKAPNLGQLYGF---YGNPNLKPEESKQWEGGFEGLTGPVNWRLSGYRNDIDNLIdYDDHTLKYYNVGKATIKGV 484
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 542 EL--EVDY-ALSKTLNLQFagTHAKHTYTNNQlinglningnnVDTAPRNVANLDLTWQAFnNLALALQWHSVSSYYTDP 618
Cdd:PRK10641  485 EWtgNFDTgPLTHQVTLDY--VDPRNAITDEP-----------LARRAKQQVKYQLDWQLY-DFDWGVTYQYLGTRYDKD 550
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|...
gi 1248244047 619 ENLHSYE-----GHDILSLRAKWQVTNNLEVLARIINLTDEAY 656
Cdd:PRK10641  551 YSTYPYQtvklgGVSLWDLAVSYPVTSHLTVRGKIANLFDKDY 593
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
22-654 4.94e-11

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 65.80  E-value: 4.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  22 NDDAIETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGANVQRGNGQEYLpALRSpvLSGAAAcggi 101
Cdd:PRK13484   26 SDKKEDTLVVTASGFTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKDVEGISITGGNEKPDI-SIRG--LSGDYT---- 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 102 LTLEDGI-----PLRAAGFCNINELFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVIT-PDTTQG-GGLVGL------ 168
Cdd:PRK13484   99 LILVDGRrqsgrESRPNGSGGFEAGFIPPVEAIERIEVIRGPMSSLYGSDAIGGVINIITkPVNNQTwDGVLGLggiiqe 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 169 --DYGSYGYARYKLRAG--------QDYGNSGIGINASVTDDTGYRDDESVkqqkinirhrfehsnlllTSGLTYTNLDQ 238
Cdd:PRK13484  179 hgKFGNSTTNDFYLSGPlikdklglQLYGGMNYRKEDSISQGTPAKDNKNI------------------TATLQFTPTES 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 239 HTagFItgFESYKNEdiAQQNFDPdafrkARSFRAWSNaqwqlkNGNVLSitPYVRDQSMDFFKHFLpgtpLETNSQTGI 318
Cdd:PRK13484  241 QK--FV--FEYGKNN--QVHTLTP-----GESLDAWTM------RGNLKQ--PNSKRETHNSRSHWV----AAWNAQGEI 297
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 319 --GVQSLYQHNLQSNVKVNlGLDgEYTRSDFTQSQNEP----TQGSAFLVATVPQ-----GKHYDYdvnATLYAPFASVE 387
Cdd:PRK13484  298 lhPEIAVYQEKVIREVKSG-KKD-KYNHWDLNYESRKPeitnTIIDAKVTAFLPEnvltiGGQFQH---AELRDDSATGK 372
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 388 WQLNKWFISAGLRYEHMQYDY--TNNM-LTGRTTEDGTECgFGgcrysrpasgknsfSNTSPKFGVSYKANKNNTLYANF 464
Cdd:PRK13484  373 KTTETQSVSIKQKAVFIENEYaaTDSLaLTGGLRLDNHEI-YG--------------SYWNPRLYAVYNLTDNLTLKGGI 437
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 465 SRGYRAPQAAEL---YQLQREQTTA------DLNPEIANNAELGL-----KGYYSNVSY-------ALAVYAMSKHNTIY 523
Cdd:PRK13484  438 AKAFRAPSIREVspgFGTLTQGGASimygnrDLKPETSVTEEIGIiysndSGFSASATLfntdfknKLTSYDIGTKDPVT 517
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 524 RDSDFFNVNDGSSRHRGIELEVDYALSKTLNLQfagthAKHTYTN------NQLINGLNINGNNVDTAPRNVANLDLTWQ 597
Cdd:PRK13484  518 GLNTFIYDNVGEANIRGVELATQIPVYDKWHVS-----ANYTFTDsrrksdDESLNGKSLKGEPLERTPRHAANAKLEWD 592
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1248244047 598 A------FNNLALALQ--WHSVSSYYTDPENLHSYEGHDI-LSLRAKWQVTNNLEVLariiNLTDE 654
Cdd:PRK13484  593 YtqditfYSSLNYTGKqiWAAQRNGAKVPRVRNGFTSMDIgLNYQILPDTLINFAVL----NVTDR 654
OMP_b-brl_3 pfam14905
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ...
324-684 7.01e-10

Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.


Pssm-ID: 434300 [Multi-domain]  Cd Length: 407  Bit Score: 61.52  E-value: 7.01e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 324 YQHNLQSNVKVNLGLDGEYTRSDFTQSQNEPTQGSAFLVATvpQGKHYDYDVNatLYAPFASVEWQLNKWFISAGLRYEH 403
Cdd:pfam14905  63 YTKPLGKKGKLEAGAKYSFRNNDNDYDYENLDNGEWVPDPS--RSNDFDYKEN--IYAAYASYSKKFGKWSYQAGLRAEY 138
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 404 MQYDYTNNmltgrttedgtecgfggcrySRPASGKNSFSNTSPKFGVSYKANKNNTLYANFS---RGYRaPQaaeLYQLQ 480
Cdd:pfam14905 139 TDIDGDSV--------------------TTNETFKRNYFNLFPSASLSYKLNDNNSLQLSLYyrrIINR-PS---YWDLN 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 481 --REQTTA--------DLNPEIANNAELGL---KGYYSNVSYALAVYAMSKHNTIYRDSDFFN---VNDGSSRHRGIELE 544
Cdd:pfam14905 195 pfRNYSDPynysqgnpNLKPEYTNSFELGYtykWKLSLSLSYRYTNDVIQQTFITDDNDNVTYttyENLGKSNSYGLELS 274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 545 VDYALSKTLNLQFAGTHAKHTYTNNQLINGlningnnvdtaprNVANLDLTWQAFNNLALALQWH-SVSSYYTDPENLHS 623
Cdd:pfam14905 275 ASFNPTKWWSLNGNLNGYYNKYKIDGSLNS-------------DFSNFGFNWNLNNTFTLPKGWSlQLNGNYRSPRVTGQ 341
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1248244047 624 YEGHDILSLRA---------KWQVTnnlevlariINLTDEAYAERADYTSFTGDRY-----FPGKPRNAMLSATY 684
Cdd:pfam14905 342 GKIKPFYSLDLglsksflkkKLTLS---------LNVNDIFNTRKFRSTTNYDNGFiqsynNKWDSRSVRLSLSY 407
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
359-685 7.57e-09

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 58.89  E-value: 7.57e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 359 AFLVATVPQGKHYDYDVNATLYAPFASVEWQL-NKWFISAGLRYEHmqydyTNNMLTGRTTEDGTecgfGGCRYS-RPAS 436
Cdd:TIGR01782 487 GGGTYTYASTAPNTYTVTEDTTAAYAMANFDTgLRLRGNVGVRYER-----TDQTSDGWQSQPAA----NGTGSVlVPVS 557
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 437 GKNSFSNTSPKFGVSYKANKNNTL------------YANFSRGYRAPQAAELYQLQREQTTADLNPEIANNAELGLKGYY 504
Cdd:TIGR01782 558 ADRDYTDVLPSLNLAYDLTDDLVLrfaasktitrpdFGDLAANTSLSDDGTGGTVTVSGGNPDLKPYESDNLDLSLEWYF 637
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 505 SNVSYA-LAVYAMSKHNTIYRDS--DFFN---------------VNDGSSRH-RGIELEVDYALSKTLNLQFA-GTHAKH 564
Cdd:TIGR01782 638 GPGGLLsAAVFYKDIKNFIVTTTstETNDgggglvvagvlvsrpVNGGKAGKiRGVELGYQQTFDFLPGPLSGfGVQANY 717
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 565 TYTNNQLINGLNINGNNVDT---APRNVANLDLTWQAFNNLA-LALQWHS----VSSYYTDPENLHSYEGHDILSLRAKW 636
Cdd:TIGR01782 718 TYVDSEADPSVDGVQRRKLPlpgLSKNTANATLYYEKGGFSArLSYNYRSdyllDVGGSNINRLDRYVDPRGQLDLSASY 797
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 1248244047 637 QVTNNLEVLARIINLTDEAYAERADYTSFTGDRYFPGkpRNAMLSATYT 685
Cdd:TIGR01782 798 QVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETG--RTYMLGLRYK 844
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
23-671 8.07e-09

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 58.74  E-value: 8.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  23 DDAIETITTTASRTEALATPYPLTISTLSEAQLNSIAPTHVEESLQRIAGanVQRGNGQEYLPALRSPVLSGAAacggIL 102
Cdd:PRK10064   27 DDDGETMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPG--VQLTNEGDNRKGVSIRGLDSSY----TL 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 103 TLEDG--IPLRAAGF-CNINELFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVIT-PDTTQGGGLVGLDYGSYGY-AR 177
Cdd:PRK10064  101 ILIDGkrVNSRNAVFrHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITkKIGQKWHGTVTVDTTIQEHrDR 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 178 YKLRAGQDYgNSG------IGINASVTDDTGYRDDesvkQQKINIRHRFEHSNLL-LTSG-----LTYTNLDQHTAGFIT 245
Cdd:PRK10064  181 GDTYNGQFF-TSGplidgvLGMKAYGSLAKREKDD----PQNSTTTDTGETPRIEgFTSRdgnveFAWTPNQNHDFTAGY 255
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 246 GFESyknediaqQNFDPDAFRKARSFR----AWSNAQWQLKNGNVLSITPYVRDQsmdffkhflpgTPLETNSQTGigvq 321
Cdd:PRK10064  256 GFDR--------QDRDSDSLDKNRLERqnysLSHNGRWDYGNSELKYYGEKVENK-----------NPGNSSPITS---- 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 322 slyqHNLQSNVKVNLGLD--------GEYTRSDFTQSQNEPTQGSAflvatvpqgkhydYDVNATLYAPFASVEWQL-NK 392
Cdd:PRK10064  313 ----ESNSIDGKYTLPLTainqfltfGGEWRHDKLSDAVNLTGGTS-------------SKTSASQYALFVEDEWRIfEP 375
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 393 WFISAGLRYEHMQydytnnmltgrttedgtecGFGgcrysrpasgknsfSNTSPKFGVSYKANKNNTLYANFSRGYRAPQ 472
Cdd:PRK10064  376 LALTTGVRMDDHE-------------------TYG--------------DHWSPRAYLVYNATDTVTVKGGWATAFKAPS 422
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 473 aaeLYQLQREQTTA------------DLNPEIANNAELGL-----KGYYSNVSYALAVYAMSKHN--TIYRDSD------ 527
Cdd:PRK10064  423 ---LLQLSPDWTSNscrgackivgspDLKPETSESWELGLyymgeEGWLEGVESSVTVFRNDVDDriSISRTSDvnaapg 499
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 528 --------------------FFNVNdgSSRHRGIELEVDYALSKTLNLQFagthakhTYTNNQLINGLNINGNNVDTAPR 587
Cdd:PRK10064  500 yqnfvgfetngrgrrvpvfrYYNVN--KARIQGVETELKIPFNDEWKLSL-------NYTYNDGRDVSNGENKPLSDLPF 570
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 588 NVANLDLTWQ--AFNNLALALQWHSVSSYYTDPENLHSYEGHDILSLRAKWQVTNNLEVLARIINLTDEAyAERADYtSF 665
Cdd:PRK10064  571 HTANGTLDWKplALEDWSFYVSGNYTGQKRADSATAKTPGGYTIWNTGAAWQVTKDVKLRAGVLNLGDKD-LSRDDY-SY 648

                  ....*...
gi 1248244047 666 T--GDRYF 671
Cdd:PRK10064  649 NedGRRYF 656
PRK13513 PRK13513
ligand-gated channel protein;
130-670 1.30e-08

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 58.24  E-value: 1.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 130 QRIEVLKGPGSALYGSNAVHGVINVITPDTTQGGGlvgldyGSygyarykLRAG---QDYGNSGIGINASVtddtgYRDD 206
Cdd:PRK13513  138 ERIEVVRGPMSSLYGSDAMGGVINIITRKVQKEWH------GS-------LRADatlQEDSKSGDIFQTNA-----YASG 199
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 207 ESVKqqkinirhrfehsNLLltsGLTytnldqhtagfITGFESYKNEDIAqqnfdPDAFRKARsfrawsnaqwqLKNGN- 285
Cdd:PRK13513  200 PLID-------------GLL---GLK-----------VSGLLSHRSEDKI-----IDGYNEQR-----------MRNGTa 236
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 286 VLSITPyvrDQSMDF---FKHFLP---GTPLETNSQTGIGVQSLYQHN---LQSNVKVNLGLDGEYTRSDFT-------Q 349
Cdd:PRK13513  237 TFSLTP---DDNNEFdfeIGRYVQdrnSTPGRTLALNGTNSDTQYDRNnyaITHNGYYDFGNSTSYIQRDETrnpsrqmK 313
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 350 SQNE--PTQGSAFLVA-TVPQGKHYDYDvnaTLY-----APFASVEWQLNKWfiSAGLRYEHmQYDYTNNM-LTgrtted 420
Cdd:PRK13513  314 SVDTifNTQTSFLLDDhTLSLGGQYRYE---ELYdkgnqLPSASDLNKLTRW--SWALFAED-EWQMTNDFaLT------ 381
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 421 gtecgfGGCRYSRpasGKNSFSNTSPK-FGVsYKANKNNTLYANFSRGYRAP---QAAELYQlqreQTT----------- 485
Cdd:PRK13513  382 ------GGIRMDQ---DQNYGTHWTPRlYGV-WHLADQWTLKGGVSTGYRSPdlrQATDNWG----QLTgggglpalilg 447
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 486 -ADLNPEIANNAELGLkgYYSN---VSYALAVYamskhNTIYRDS-----------------------DFFN--VNDGSS 536
Cdd:PRK13513  448 nSDLKPEKSISQEIGI--LWDNqenLNASVTLF-----NTDFKDKitevrncdttntdgqcvfnginyDFISdrINVDKA 520
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 537 RHRGIELEVDYALSKTLNLQfagthAKHTYTNNQlINGLNINGNNVDTAPRNVANLDLTWQAFNNLAL--ALQWHSVSSY 614
Cdd:PRK13513  521 NMRGVEATFNWDINQAWSLA-----TNYTFTQSE-QKSGAFAGQPLNQMPKHMANATLNWQTTEDFATwiRINYRGKTSE 594
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1248244047 615 YTD----PENLHSYEGHDilsLRAKWQVTNNLEVLARIINLTDeayaERADYTSF----TGDRY 670
Cdd:PRK13513  595 YLNrtsmGSGTPSYTFVD---LGASYQLTKELRLMGGVYNLLD----KRVDIDVNdkvlDGRRY 651
PRK09840 PRK09840
catecholate siderophore receptor Fiu; Provisional
389-682 1.34e-06

catecholate siderophore receptor Fiu; Provisional


Pssm-ID: 182105 [Multi-domain]  Cd Length: 761  Bit Score: 51.73  E-value: 1.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 389 QLN-KWFISAGLRYEHMQYDYtNNMLTGRTTEDGTECGFGGCRYSRP---ASGKNSFSNTSPKFGVSYKANKNNTLYANF 464
Cdd:PRK09840  456 QLTrDWELNGGIRLDNYHTEY-DSATACGGSGRGAITCPAGVAKGSPvttVDTAKSGNLVNWKAGALYKLTENGNVYINY 534
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 465 SRGYRAPQAAElYQLQREQTTADLN-----PEIANNAELGLKGYYSNVSYAL--AVYAMSKHNTIYRDSDFFNVNDGSSR 537
Cdd:PRK09840  535 AVSQQPPGGSN-FALAQSGSGNSANrtdfkPQKANTSEIGTKWQVLDKRLLLtaALFRTDIENEVEQNDDGTYSQYGKKR 613
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 538 HRGIELEVDYALSKTLNLQFAGTHAKHTYTNNQLINGLNINGnnVDTAPRNVANLDLTWQAFNNLALALQWHSVSSYYTD 617
Cdd:PRK09840  614 VEGYELSVAGNITPAWQVIAGYTQQKATVKNGKDVAQDGSSS--LPYTPEHAFTLWSQYQATDDLSVGGGARYIGSMHRG 691
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1248244047 618 -------PENLHSYEghdILSLRAKWQVTNNLEVLARIINLTDEAYAERADYTsftGDRYFPGKPRNAMLSA 682
Cdd:PRK09840  692 sdgavgtPAFTEGYW---VADAKLGYRVNRNLDLQLNVYNLFDTDYVASINKS---GYRYHPGEPRTFLLTA 757
PRK10044 PRK10044
ferrichrome outer membrane transporter; Provisional
387-620 2.05e-06

ferrichrome outer membrane transporter; Provisional


Pssm-ID: 236643 [Multi-domain]  Cd Length: 727  Bit Score: 50.91  E-value: 2.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 387 EWqlNKWFISAGLRYEHMQYDyTNNMLTGRTTE--DGTECGFGGCRYSrpasgknsFSN-TSPKFgvSYKANKNNTLYAN 463
Cdd:PRK10044  454 EW--DKWLVTLGGRYDWADQS-SLNRVNGTTDKrdDKQFTWRGGVNYL--------FDNgITPYF--SYSESFEPSSGTG 520
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 464 FSRGYRAPQAAELYqlqreqttadlnpeiannaELGLKgYYSN---VSYALAVYAMSKHNTIYRDSD--FFNVNDGSSRH 538
Cdd:PRK10044  521 KDGNIFAPSKGKQY-------------------EAGVK-YVPKdrpIVVTGAVYQLTKTNNLTADPEnsFFSVQGGEIRA 580
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 539 RGIELEVDYALSKTLNLQfagthAKHTYTNNQLINGLNINGNNVDTAPRNVANL--DLTWQ--AFNNLALALQWHSVSSY 614
Cdd:PRK10044  581 RGVELEAKAALSANVNVT-----GSYTYTDAEYTTDTTYKGNTPAQVPKHMASLwaDYTFFdgPLSGLTLGTGGRYTGSS 655

                  ....*.
gi 1248244047 615 YTDPEN 620
Cdd:PRK10044  656 YGDPAN 661
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
127-161 6.22e-06

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 49.64  E-value: 6.22e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1248244047 127 EMAQRIEVLKGPGSALYGSNAVHGVINVITPDTTQ 161
Cdd:PRK13524  144 EMIERIEVLRGPAAARYGNGAAGGVVNIITKKPTG 178
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
127-156 9.14e-06

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 48.98  E-value: 9.14e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 1248244047 127 EMAQRIEVLKGPGSALYGSNAVHGVINVIT 156
Cdd:PRK13528  142 EMVERIEVIRGPAAARYGSGAAGGVVNIIT 171
PRK14050 PRK14050
TonB-dependent siderophore receptor;
26-155 9.33e-06

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 49.03  E-value: 9.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  26 IETITTTASRTEALATPYPLTISTLSEAQLNSIAPTH-VEESLQRIAGANVQR-GNGQE----YLPALRspvlsgAAACG 99
Cdd:PRK14050   62 VAKATATGSKTDTPITEIPQSVSVVGRQEMDDRGVTNkVDEALRYTPGVLSQPfGTDGDtdwfYIRGFD------ATQTG 135
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1248244047 100 GILtleDGIPLRAAGFCNinelFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVI 155
Cdd:PRK14050  136 VFL---DGLNLFSYGFGG----FQIDPFMLERVEVLKGPASVLYGGSNPGGIVNMV 184
PRK10003 PRK10003
ferric-rhodotorulic acid outer membrane transporter; Provisional
428-684 4.13e-05

ferric-rhodotorulic acid outer membrane transporter; Provisional


Pssm-ID: 236640 [Multi-domain]  Cd Length: 729  Bit Score: 46.78  E-value: 4.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 428 GCRYS----RPASGKNSFSNTSPKFGVSYKANKNNTLYANFSRGYRaPQAaelyqlQREQTTADLNPEIANNAELGLKG- 502
Cdd:PRK10003  472 GARYTnwrvDTLTYSMEKNHTTPYAGLVYDINDNWSTYASYTSIFQ-PQN------DRDSSGKYLAPITGNNYELGLKSd 544
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 503 -YYSNVSYALAVYAMSKHN---------------TIYRDSDffnvndgSSRHRGIELEVDYALSKTLNLQFAGThaKHTY 566
Cdd:PRK10003  545 wMNSRLTTTLAIFRIEQDNvaqstgtpipgsngeTAYKAVD-------GTVSKGVEFELNGAITDNWQLTFGAT--RYIA 615
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047 567 TNNQLINGLNINgnnvdtaPRNVANLDLTWQAFNNLALAL----QWHsvSSYYTD---PENLHSYE--GHDILSLRAKWQ 637
Cdd:PRK10003  616 EDNEGNAVNPNL-------PRTTVKLFTRYRLPVMPELTVgggvNWQ--NRVYTDtvtPYGTFRAEqgSYALVDLFTRYQ 686
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1248244047 638 VTNNLEVLARIINLTDEAYaeradYTSFTGDRYFpGKPRNAMLSATY 684
Cdd:PRK10003  687 VTKNFSVQGNVNNLFDKTY-----DTNVEGSIVY-GAPRNFSITATY 727
PRK14049 PRK14049
ferrioxamine B receptor precursor protein; Provisional
32-161 8.92e-03

ferrioxamine B receptor precursor protein; Provisional


Pssm-ID: 172541 [Multi-domain]  Cd Length: 726  Bit Score: 39.50  E-value: 8.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248244047  32 TASRTEA-LATPY---PLTISTLSEAQLNSIAPTHVEESLQRIAGANVqrgNGQEYLPALRSPVLSG-AAACGGILtlED 106
Cdd:PRK14049   64 TSSATGAkVDTPFletPQSISSVTEQQLKDRNPQTLLETLAYTPGARV---GAFGFDPRFDAFFVRGfDVTYTGVF--RD 138
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1248244047 107 GIPLRAAgfcnINELFEAHSEMAQRIEVLKGPGSALYGSNAVHGVINVITPDTTQ 161
Cdd:PRK14049  139 NLRQPGA----SSSIFKTEPYGLEGVSILRGPSSALYGASGAGGLFNLITKRPTE 189
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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