|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
1-401 |
0e+00 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 742.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWDN 80
Cdd:PRK08242 1 MTEAYIYDAVRTPRGKGKKDGSLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGDQGADIARTAVLAAGLPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGAWAFDPETNMACDFIPQGIGADLIATLDG 160
Cdd:PRK08242 81 TVPGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVPMGSDGGAWAMDPSTNFPTYFVPQGISADLIATKYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 161 YSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDQAGVVILAQDEFIKPQTTAESLAQLKPSFANMGQM-GFDAIALQK 239
Cdd:PRK08242 161 FSREDVDAYAVESQQRAAAAWAEGYFAKSVVPVKDQNGLTILDHDEHMRPGTTMESLAKLKPSFAMMGEMgGFDAVALQK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 240 YPEAGQVNHVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARKALAKAGLNIEDI 319
Cdd:PRK08242 241 YPEVERINHVHHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPATRKALAKAGLTVDDI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 320 DLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLCVGGGMGIATIIE 399
Cdd:PRK08242 321 DLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGKRTALITLCVGGGMGIATIIE 400
|
..
gi 1253006213 400 RV 401
Cdd:PRK08242 401 RV 402
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
1-401 |
2.98e-172 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 486.50 E-value: 2.98e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKgkKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGdQGADIAKTAAIAAGWDN 80
Cdd:COG0183 1 MREVVIVDAVRTPFGR--FGGALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAG-QGQNPARQAALLAGLPE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGAWAFDPETNM-----------ACDFIPQG 149
Cdd:COG0183 78 SVPAVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRAPMLLPKARWGYRMNAKLvdpminpgltdPYTGLSMG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 150 IGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPV--KDQAGVVILAQDEFIKPQTTAESLAQLKPSFANM 227
Cdd:COG0183 158 ETAENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVevPDRKGEVVVDRDEGPRPDTTLEKLAKLKPAFKKD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 228 GqmgfdaialqkypeagqvnhVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARK 307
Cdd:COG0183 238 G--------------------TVTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRK 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 308 ALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLC 387
Cdd:COG0183 298 ALARAGLTLDDIDLIEINEAFAAQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGRYGLATMC 377
|
410
....*....|....
gi 1253006213 388 VGGGMGIATIIERV 401
Cdd:COG0183 378 IGGGQGIALIIERV 391
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
5-400 |
3.40e-157 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 448.08 E-value: 3.40e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 5 YIIDAIRTPRGKGKkdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGdQGADIAKTAAIAAGWDNDVAG 84
Cdd:cd00751 1 VIVSAVRTPIGRFG--GALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAG-EGQNPARQAALLAGLPESVPA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 85 VQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGAWAFDPETNMACDF-----------IPQGIGAD 153
Cdd:cd00751 78 TTVNRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPKARRGGRLGLNTLDGMlddgltdpftgLSMGITAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 154 LIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDQA--GVVILAQDEFIKPQTTAESLAQLKPSFANmgqmg 231
Cdd:cd00751 158 NVAEKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVEVPGrkGPVVVDRDEGPRPDTTLEKLAKLKPAFKK----- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 232 fdaialqkypeagqvNHVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARKALAK 311
Cdd:cd00751 233 ---------------DGTVTAGNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKR 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 312 AGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLCVGGG 391
Cdd:cd00751 298 AGLTLDDIDLIEINEAFAAQALACLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGLATMCIGGG 377
|
....*....
gi 1253006213 392 MGIATIIER 400
Cdd:cd00751 378 QGAAMVIER 386
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
1-401 |
3.27e-152 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 436.51 E-value: 3.27e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKK-DGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWD 79
Cdd:PRK06025 1 MAEAYIIDAVRTPRGIGKVgKGALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGKQGGDLGRMAALDAGYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 80 NDVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGAWAFDPETNMACDFIP---------QGI 150
Cdd:PRK06025 81 IKASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSYTAAMAAEDMAAGKPPLGMGSGNLRlralhpqshQGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 151 GADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDQAGVVILAQDEFIKPQTTAESLAQLKPSFANMGQM 230
Cdd:PRK06025 161 CGDAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVPVYRDDGSVALDHEEFPRPQTTAEGLAALKPAFTAIADY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 231 GFD-------AIALQKYPEAgQVNHVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAP 303
Cdd:PRK06025 241 PLDdkgttyrGLINQKYPDL-EIKHVHHAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTLMLNAPVP 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 304 AARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGM 383
Cdd:PRK06025 320 AAKKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELERRGLKRGL 399
|
410
....*....|....*...
gi 1253006213 384 ATLCVGGGMGIATIIERV 401
Cdd:PRK06025 400 VTMCAAGGMAPAIIIERV 417
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
6-399 |
1.74e-144 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 415.86 E-value: 1.74e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 6 IIDAIRTPRGKGKkdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQgADIAKTAAIAAGWDNDVAGV 85
Cdd:TIGR01930 1 IVAAARTPIGKFG--GSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQ-QNIARQAALLAGLPESVPAY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 86 QINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMG-SDGGAWAFDP-----------ETNMACDFIPQGIGAD 153
Cdd:TIGR01930 78 TVNRQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGvPRSLRWGVKPgnaeledarlkDLTDANTGLPMGVTAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 154 LIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPV--KDQAGVVILAQDEFIKPQTTAESLAQLKPSFAnmgqmg 231
Cdd:TIGR01930 158 NLAKKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVtvKGRKGPVTVSSDEGIRPNTTLEKLAKLKPAFD------ 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 232 fdaialqkypeagqVNHVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARKALAK 311
Cdd:TIGR01930 232 --------------PDGTVTAGNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKK 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 312 AGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLCVGGG 391
Cdd:TIGR01930 298 AGLSISDIDLFEINEAFAAQVLACIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGLATMCIGGG 377
|
....*...
gi 1253006213 392 MGIATIIE 399
Cdd:TIGR01930 378 QGAAVILE 385
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
1-401 |
1.12e-120 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 355.23 E-value: 1.12e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKkdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGdQGADIAKTAAIAAGWDN 80
Cdd:PRK05790 1 MKDVVIVSAARTPIGKFG--GALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAG-AGQNPARQAALKAGLPV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSR---VAMGSDGG----------AWAFDPETNMACDfIP 147
Cdd:PRK05790 78 EVPALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQaphVLPGSRWGqkmgdvelvdTMIHDGLTDAFNG-YH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 148 QGIGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPV--KDQAG-VVILAQDEFIKPQTTAESLAQLKPSF 224
Cdd:PRK05790 157 MGITAENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVtiKQRKGdPVVVDTDEHPRPDTTAESLAKLRPAF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 225 AnmgqmgfdaialqkypEAGQVnhvhHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPA 304
Cdd:PRK05790 237 D----------------KDGTV----TAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPA 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 305 ARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMA 384
Cdd:PRK05790 297 IRKALEKAGWSLADLDLIEINEAFAAQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAKKGLA 376
|
410
....*....|....*..
gi 1253006213 385 TLCVGGGMGIATIIERV 401
Cdd:PRK05790 377 TLCIGGGQGVALIVERP 393
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
1-401 |
1.72e-119 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 352.09 E-value: 1.72e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPrgKGKKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWDN 80
Cdd:PRK07801 1 MAEAYIVDAVRTP--VGKRKGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTIGPQAGNIARTSWLAAGLPE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSD---GGAWAFDPETNMACDF--------IPQG 149
Cdd:PRK07801 79 EVPGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPISSAmtaGEQLGFTSPFAESKGWlhrygdqeVSQF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 150 IGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDqagvviLAQDEFIKpQTTAESLAQLKPSFanmgq 229
Cdd:PRK07801 159 RGAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPVGG------VTVDEGPR-ETSLEKMAGLKPLV----- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 230 mgfdaialqkypEAGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARKAL 309
Cdd:PRK07801 227 ------------EGGRLT----AAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYAL 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 310 AKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLCVG 389
Cdd:PRK07801 291 EKTGLSIDDIDVVEINEAFAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGRYGLQTMCEG 370
|
410
....*....|..
gi 1253006213 390 GGMGIATIIERV 401
Cdd:PRK07801 371 GGTANVTIIERL 382
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
1-401 |
1.95e-106 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 318.83 E-value: 1.95e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKKdGALHEVKPIRLLTTLLNELQQRH-NLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWD 79
Cdd:PRK08947 1 MEDVVIVDAIRTPMGRSKG-GAFRNVRAEDLSAHLMRSLLARNpALDPAEIDDIIWGCVQQTLEQGFNIARNAALLAGIP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 80 NDVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAM--GSDggawaFDPE--TNMACDFIPQGIGADLI 155
Cdd:PRK08947 80 HSVPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVPMnhGVD-----FHPGlsKNVAKAAGMMGLTAEML 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 156 ATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVK--DQAGVVILA-QDEFIKPQTTAESLAQLKPSFAnmgqmgf 232
Cdd:PRK08947 155 GKMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPTEghDADGVLKLFdYDEVIRPETTVEALAALRPAFD------- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 233 daialqkyPEAGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARKALAKA 312
Cdd:PRK08947 228 --------PVNGTVT----AGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRA 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 313 GLNIEDIDLFEVNEAFAAVVLRFITEL----QVDpAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLCV 388
Cdd:PRK08947 296 GLSISDIDVFELNEAFAAQSLPCLKDLglldKMD-EKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQFGLATMCI 374
|
410
....*....|...
gi 1253006213 389 GGGMGIATIIERV 401
Cdd:PRK08947 375 GLGQGIATVFERV 387
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
1-401 |
1.78e-105 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 316.90 E-value: 1.78e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPrgKGKKDGALHEVKPIRLLTTLLNELQQRH-NLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWD 79
Cdd:PRK09050 1 MTEAFICDAIRTP--IGRYGGALSSVRADDLGAVPLKALMARNpGVDWEAVDDVIYGCANQAGEDNRNVARMSALLAGLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 80 NDVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRV--AMGSDGGAWAFDPE---TNMACDFI-------- 146
Cdd:PRK09050 79 VSVPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRApfVMGKADSAFSRQAEifdTTIGWRFVnplmkaqy 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 147 -----PQGigADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPV---KDQAGVVILAQDEFIKPQTTAESLA 218
Cdd:PRK09050 159 gvdsmPET--AENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVtipQKKGDPVVVDRDEHPRPETTLEALA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 219 QLKPSFAnmgqmgfdaialqkypEAGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIML 298
Cdd:PRK09050 237 KLKPVFR----------------PDGTVT----AGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMG 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 299 TGPAPAARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQV--DPAKVNVNGGAIALGHPLGATGAMILGTLLDELER 376
Cdd:PRK09050 297 IGPAPATRKLLARLGLTIDQFDVIELNEAFAAQGLAVLRQLGLadDDARVNPNGGAIALGHPLGMSGARLVLTALHQLER 376
|
410 420
....*....|....*....|....*
gi 1253006213 377 QDKKRGMATLCVGGGMGIATIIERV 401
Cdd:PRK09050 377 TGGRYALCTMCIGVGQGIALAIERV 401
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
1-401 |
1.99e-104 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 314.25 E-value: 1.99e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKKdGALHEVKPIRLL-TTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWD 79
Cdd:PRK09052 5 LQDAYIVAATRTPVGKAPR-GMFKNTRPDDLLaHVLRSAVAQVPGLDPKLIEDAIVGCAMPEAEQGLNVARIGALLAGLP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 80 NDVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGAWA---FDPETNMACDFiPQGIGADLIA 156
Cdd:PRK09052 84 NSVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMVPMMGNKPSMSpaiFARDENVGIAY-GMGLTAEKVA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 157 TLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVP--VKD-----QAGVVILAQ-----DEFIKPQTTAESLAQLKPSF 224
Cdd:PRK09052 163 EQWKVSREDQDAFALESHQKAIAAQQAGEFKDEITPyeITErfpdlATGEVDVKTrtvdlDEGPRADTSLEGLAKLKPVF 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 225 ANMGQMGfdaialqkypeagqvnhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPA 304
Cdd:PRK09052 243 ANKGSVT--------------------AGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEA 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 305 ARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMA 384
Cdd:PRK09052 303 IPAALKQAGLKQDDLDWIELNEAFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLKYGMV 382
|
410
....*....|....*..
gi 1253006213 385 TLCVGGGMGIATIIERV 401
Cdd:PRK09052 383 TMCVGTGMGAAGIFERL 399
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
1-401 |
1.51e-101 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 306.65 E-value: 1.51e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTP-----RGKGKKDgALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIA 75
Cdd:PRK06445 1 LEDVYLVDFARTAfsrfrPKDPQKD-VFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALQVGENWLYGGRHPIFL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 76 AGWDNDVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSD-----GGAWAFDPET---NMACDFIp 147
Cdd:PRK06445 80 ARLPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTPMGDNphiepNPKLLTDPKYieyDLTTGYV- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 148 QGIGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDQAG--VVILAQDEFIKPQTTAESLAQLKPSFA 225
Cdd:PRK06445 159 MGLTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIEVEVEgkKKVVDVDQSVRPDTSLEKLAKLPPAFK 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 226 NMGqmgfdaialqkypeagqvnhVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAA 305
Cdd:PRK06445 239 PDG--------------------VITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPAS 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 306 RKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMAT 385
Cdd:PRK06445 299 KKALEKAGLSVKDIDLWEINEAFAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKDYGVAT 378
|
410
....*....|....*.
gi 1253006213 386 LCVGGGMGIATIIERV 401
Cdd:PRK06445 379 LCVGGGQGGAVVLERV 394
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
1-401 |
4.09e-101 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 305.11 E-value: 4.09e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPrgKGKKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWDN 80
Cdd:PRK07850 1 MGNPVIVEAVRTP--IGKRNGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCVTQAGEQSNNITRTAWLHAGLPY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGAWAFDPET-NMACDFIPQGIGADLIATLD 159
Cdd:PRK07850 79 HVGATTIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRVPLGANAGPGRGLPRPdSWDIDMPNQFEAAERIAKRR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 160 GYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVK---------DQAGVVILAQDEFIKpQTTAESLAQLKPSFANmgqm 230
Cdd:PRK07850 159 GITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQapvldeegqPTGETRLVTRDQGLR-DTTMEGLAGLKPVLEG---- 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 231 gfdaialqkypeagqvnHVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARKALA 310
Cdd:PRK07850 234 -----------------GIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 311 KAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLCVGG 390
Cdd:PRK07850 297 KAGMKIGDIDLVEINEAFASVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKSTALITMCAGG 376
|
410
....*....|.
gi 1253006213 391 GMGIATIIERV 401
Cdd:PRK07850 377 ALSTGTIIERI 387
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
1-401 |
1.17e-99 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 301.65 E-value: 1.17e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTprGKGKKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWDN 80
Cdd:PRK06504 1 MAEAYIVAAART--AGGRKGGRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVGEQATNVARNAVLASKLPE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGS-------DGGAWAFDPETNMACDFI--PQGIG 151
Cdd:PRK06504 79 SVPGTSIDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRVPMGSpstlpakNGLGHYKSPGMEERYPGIqfSQFTG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 152 ADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVK---DQAGVVILAQDEFIKPQTTAESLAQLKPsfanmg 228
Cdd:PRK06504 159 AEMMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLEitrADGSGEMHTVDEGIRFDATLEGIAGVKL------ 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 229 qmgfdaIAlqkypEAGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARKA 308
Cdd:PRK06504 233 ------IA-----EGGRLT----AATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATERA 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 309 LAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLCV 388
Cdd:PRK06504 298 LKKAGMKIDDIDLYEVNEAFASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKRYGLQTMCE 377
|
410
....*....|...
gi 1253006213 389 GGGMGIATIIERV 401
Cdd:PRK06504 378 GGGMANVTIVERL 390
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
1-400 |
4.88e-96 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 293.06 E-value: 4.88e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKKdGALHEVKPIRLLTTLLNE-LQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWD 79
Cdd:PRK07851 1 MPEAVIVSTARSPIGRAFK-GSLKDMRPDDLAAQMVRAaLDKVPALDPTDIDDLMLGCGLPGGEQGFNMARVVAVLLGYD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 80 NdVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGG-------------------------AWA 134
Cdd:PRK07851 80 F-LPGTTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSRFAKGNSDSlpdtknplfaeaqartaaraeggaeAWH 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 135 fDPETN--MACDFIPQGIGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDQAGVVIlAQDEFIKPQT 212
Cdd:PRK07851 159 -DPREDglLPDVYIAMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPVTLPDGTVV-STDDGPRAGT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 213 TAESLAQLKPSFAnmgqmgfdaialqkyPEaGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGT 292
Cdd:PRK07851 237 TYEKVSQLKPVFR---------------PD-GTVT----AGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGL 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 293 DPAIMLTGPAPAARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLD 372
Cdd:PRK07851 297 SPEIMGLGPVEASKQALARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLN 376
|
410 420
....*....|....*....|....*...
gi 1253006213 373 ELERQDKKRGMATLCVGGGMGIATIIER 400
Cdd:PRK07851 377 NLQTHDKTFGLETMCVGGGQGMAMVLER 404
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
1-401 |
1.79e-93 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 286.09 E-value: 1.79e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTprGKGKKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWDN 80
Cdd:PRK09051 2 MREVVVVSGVRT--AIGTFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIPTEPRDMYLSRVAAINAGVPQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGAW--------AFDPETN-MACDF--IPQG 149
Cdd:PRK09051 80 ETPAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPYLLPAARWgarmgdakLVDMMVGaLHDPFgtIHMG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 150 IGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPV--KDQAGVVILAQDEFIKPQTTAESLAQLKPSFANm 227
Cdd:PRK09051 160 VTAENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVeiKTRKGEVVFDTDEHVRADTTLEDLAKLKPVFKK- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 228 gqmgfdaialqkypEAGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARK 307
Cdd:PRK09051 239 --------------ENGTVT----AGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQK 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 308 ALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLC 387
Cdd:PRK09051 301 ALERAGLTVADLDVIEANEAFAAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGRYALVTMC 380
|
410
....*....|....
gi 1253006213 388 VGGGMGIATIIERV 401
Cdd:PRK09051 381 IGGGQGIAAIFERL 394
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
1-401 |
3.38e-90 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 277.40 E-value: 3.38e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKKdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWDN 80
Cdd:PRK07661 1 MREAVIVAGARTPVGKAKK-GSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMPEAEQGLNMARNIGALAGLPY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDggawAFDPETNMACD----FIPQGIGADLIA 156
Cdd:PRK07661 80 TVPAITINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVPMMGH----VVRPNPRLVEAapeyYMGMGHTAEQVA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 157 TLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPV-----------KDQAGVVILAQDEFIKPQTTAESLAQLKPSFA 225
Cdd:PRK07661 156 VKYGISREDQDAFAVRSHQRAAKALAEGKFADEIVPVdvtlrtvgennKLQEETITFSQDEGVRADTTLEILGKLRPAFN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 226 NMGQMGfdaialqkypeagqvnhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAA 305
Cdd:PRK07661 236 VKGSVT--------------------AGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAI 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 306 RKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMAT 385
Cdd:PRK07661 296 PKALKLAGLELSDIGLFELNEAFASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVT 375
|
410
....*....|....*.
gi 1253006213 386 LCVGGGMGIATIIERV 401
Cdd:PRK07661 376 MCIGGGMGAAGVFELL 391
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
6-400 |
1.07e-88 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 275.49 E-value: 1.07e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 6 IIDAIRTPRGKGKKdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWDNDVAGV 85
Cdd:PLN02287 50 IVAAYRTPICKAKR-GGFKDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVVGTVLAPGSQRANECRMAAFYAGFPETVPVR 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 86 QINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGawaFDPETN---MACD-FIPQGIGADLIATLDGY 161
Cdd:PLN02287 129 TVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTNPMAWEGG---VNPRVEsfsQAQDcLLPMGITSENVAERFGV 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 162 SRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDQ--------AGVVILAQDEFIKPQTTAESLAQLKPSFANMGqmgfd 233
Cdd:PLN02287 206 TREEQDQAAVESHRKAAAATASGKFKDEIVPVHTKivdpktgeEKPIVISVDDGIRPNTTLADLAKLKPVFKKNG----- 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 234 aialqkypeagqvnhVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARKALAKAG 313
Cdd:PLN02287 281 ---------------TTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAVAIPAAVKAAG 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 314 LNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELER--QDKKRGMATLCVGGG 391
Cdd:PLN02287 346 LELDDIDLFEINEAFASQFVYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATLLHEMKRrgKDCRFGVVSMCIGTG 425
|
....*....
gi 1253006213 392 MGIATIIER 400
Cdd:PLN02287 426 MGAAAVFER 434
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
1-401 |
1.88e-87 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 270.71 E-value: 1.88e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPrgKGKKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGAdIAKTAAIAAGWDN 80
Cdd:PRK06205 1 MRDAVICEPVRTP--VGRFGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPA-IGRVAALDAGLPV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGAW-------------AFDPETNMACDF-I 146
Cdd:PRK06205 78 TVPGMQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNVEFYTTDMRWgvrgggvqlhdrlARGRETAGGRRFpV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 147 PQGI--GADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVK---DQAGVVILAQDEFIKPQTTAESLAQLK 221
Cdd:PRK06205 158 PGGMieTAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVTvpqRKGDPTVVDRDEHPRADTTLESLAKLR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 222 PsfanmgqmgfdaIALQKYPEAgqvnhVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGP 301
Cdd:PRK06205 238 P------------IMGKQDPEA-----TVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGP 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 302 APAARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPA---KVNVNGGAIALGHPLGATGAMILGTLLDELERQD 378
Cdd:PRK06205 301 VPATEKALARAGLTLDDIDLIELNEAFAAQVLAVLKEWGFGADdeeRLNVNGSGISLGHPVGATGGRILATLLRELQRRQ 380
|
410 420
....*....|....*....|...
gi 1253006213 379 KKRGMATLCVGGGMGIATIIERV 401
Cdd:PRK06205 381 ARYGLETMCIGGGQGLAAVFERV 403
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
1-401 |
8.73e-87 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 268.95 E-value: 8.73e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKgkKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWDN 80
Cdd:PRK08131 1 MLDAYIYDGLRSPFGR--HAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGEDSRNVARNALLLAGLPV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRV--AMGSDGGAWA-----FDP-----------ETNMA 142
Cdd:PRK08131 79 TVPGQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRApfVMGKAESAFSrdakvFDTtigarfpnpkiVAQYG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 143 CDFIPQGigADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDQAG----VVILAQDEFIKPQTTAESLA 218
Cdd:PRK08131 159 NDSMPET--GDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEVPQGrklpPKLVAEDEHPRPSSTVEALT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 219 QLKPSFanmgqmgfdaialqkypEAGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIML 298
Cdd:PRK08131 237 KLKPLF-----------------EGGVVT----AGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMG 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 299 TGPAPAARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQV--DPAKVNVNGGAIALGHPLGATGAMILGTLLDELER 376
Cdd:PRK08131 296 IGPVEAIKKALARAGLTLDDMDIIEINEAFASQVLGCLKGLGVdfDDPRVNPNGGAIAVGHPLGASGARLALTAARELQR 375
|
410 420
....*....|....*....|....*
gi 1253006213 377 QDKKRGMATLCVGGGMGIATIIERV 401
Cdd:PRK08131 376 RGKRYAVVSLCIGVGQGLAMVIERV 400
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
3-401 |
1.43e-79 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 250.33 E-value: 1.43e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 3 EAYIIDAIRTPRGKGKkdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTpIGDQGADIAKTAAIAAGWDNDV 82
Cdd:PRK06633 4 PVYITHAKRTAFGSFM--GSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVI-TGGSGQNPARQTLIHAGIPKEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 83 AGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGAWA------------FDPETNMACDFIpQGI 150
Cdd:PRK06633 81 PGYTINKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMSLGMHGSYIRAGAkfgdikmvdlmqYDGLTDVFSGVF-MGI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 151 GADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVK--DQAGVVILAQDEFIKPQTTAESLAQLKPSFANmg 228
Cdd:PRK06633 160 TAENISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKDEILPIEvtIKKTTSLFDHDETVRPDTSLEILSKLRPAFDK-- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 229 qmgfdaialqkypeagqvNHVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARKA 308
Cdd:PRK06633 238 ------------------NGVVTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKA 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 309 LAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLCV 388
Cdd:PRK06633 300 LSKAGWSVNDLEVIEVNEAFAAQSIYVNREMKWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGLVTLCI 379
|
410
....*....|...
gi 1253006213 389 GGGMGIATIIERV 401
Cdd:PRK06633 380 GGGMGMAMCVEAV 392
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
1-399 |
8.16e-79 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 248.09 E-value: 8.16e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKgkKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGdQGADIAKTAAIAAGWDN 80
Cdd:PRK08235 1 MSKTVIVSAARTPFGK--FGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGG-QGQIPSRQAARAAGIPW 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGGAWAF---DPET-------NMACDF--IPQ 148
Cdd:PRK08235 78 EVQTETVNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMSNAPYILPGARWGYrmgDNEVidlmvadGLTCAFsgVHM 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 149 GIGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPV---KDQAGVVILAQDEFIKPQTTAESLAQLKPSFA 225
Cdd:PRK08235 158 GVYGGEVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVtipQRKGDPIVVAKDEAPRKDTTIEKLAKLKPVFD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 226 NMGQMGfdaialqkypeagqvnhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAA 305
Cdd:PRK08235 238 KTGTIT--------------------AGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAI 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 306 RKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMAT 385
Cdd:PRK08235 298 NALLEKTGKTVEDIDLFEINEAFAAVALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGIAA 377
|
410
....*....|....
gi 1253006213 386 LCVGGGMGIATIIE 399
Cdd:PRK08235 378 ICSGGGQGDAVLIE 391
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
1-400 |
2.69e-76 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 241.72 E-value: 2.69e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKkdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGdQGADIAKTAAIAAGWDN 80
Cdd:PRK05656 1 MQDVVIVAATRTAIGSFQ--GSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAG-AGQNPARQAAIKAGLPH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRV--------------------AMGSDGGAWAFDpETN 140
Cdd:PRK05656 78 SVPAMTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLApyvlpgartglrmghaqlvdSMITDGLWDAFN-DYH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 141 MacdfipqGIGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPV---KDQAGVVILAQDEFIKPQTTAESL 217
Cdd:PRK05656 157 M-------GITAENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPIlipQRKGEPLAFATDEQPRAGTTAESL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 218 AQLKPSFANMGQMGfdaialqkypeagqvnhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIM 297
Cdd:PRK05656 230 AKLKPAFKKDGSVT--------------------AGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIM 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 298 LTGPAPAARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQ 377
Cdd:PRK05656 290 GIGPVSATRRCLDKAGWSLAELDLIEANEAFAAQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRR 369
|
410 420
....*....|....*....|...
gi 1253006213 378 DKKRGMATLCVGGGMGIATIIER 400
Cdd:PRK05656 370 DAKKGLATLCIGGGQGVALAIER 392
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
5-401 |
3.38e-76 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 242.62 E-value: 3.38e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 5 YIIDAIRTPRGKGKkdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQgADIAKTAAIAAGWDNDVAG 84
Cdd:PRK08170 6 YIVDGARTPFLKAR--GGPGPFSASDLAVAAGRALLNRQPFAPDDLDEVILGCAMPSPDE-ANIARVVALRLGCGEKVPA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 85 VQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSR--VAMGSDGGAW------------------AFDPE------ 138
Cdd:PRK08170 83 WTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHapLLFSEKMVRWlagwyaaksigqklaalgKLRPSylapvi 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 139 ------TNMACDFIpQGIGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFeRSIVPVKDQAGVViLAQDEFIKPQT 212
Cdd:PRK08170 163 gllrglTDPVVGLN-MGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRL-KEVVPLFDRDGKF-YDHDDGVRPDS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 213 TAESLAQLKPSFAnmgqmgfdaialQKYpeaGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGT 292
Cdd:PRK08170 240 SMEKLAKLKPFFD------------RPY---GRVT----AGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAAL 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 293 DPAIMLTGPAPAARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQ-----------------VDPAKVNVNGGAIAL 355
Cdd:PRK08170 301 DPSQMGLGPVHAATPLLQRHGLTLEDLDLWEINEAFAAQVLACLAAWAdeeycreqlgldgalgeLDRERLNVDGGAIAL 380
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1253006213 356 GHPLGATGAMILGTLLDELERQDKKRGMATLCVGGGMGIATIIERV 401
Cdd:PRK08170 381 GHPVGASGARIVLHLLHALKRRGTKRGIAAICIGGGQGGAMLLERV 426
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
1-399 |
8.13e-73 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 232.74 E-value: 8.13e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKKdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDQGADIAKTAAIAAGWDN 80
Cdd:PRK07108 1 MTEAVIVSTARTPLAKSWR-GAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMGCANPEGATGANIARQIALRAGLPV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVA------MGSDGGAWAFDPETNMacdfiPQGIGADL 154
Cdd:PRK07108 80 TVPGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESISCVQnemnrhMLREGWLVEHKPEIYW-----SMLQTAEN 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 155 IATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDQAGV------------VILAQDEFIKPQTTAESLAQLKP 222
Cdd:PRK07108 155 VAKRYGISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITVTAGVadkatgrlftkeVTVSADEGIRPDTTLEGVSKIRS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 223 SFanmgqmgfdaialqkypEAGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPA 302
Cdd:PRK07108 235 AL-----------------PGGVIT----AGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPV 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 303 PAARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRG 382
Cdd:PRK07108 294 FAVPKLLKQAGLKVDDIDLWELNEAFAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAKYV 373
|
410
....*....|....*..
gi 1253006213 383 MATLCVGGGMGIATIIE 399
Cdd:PRK07108 374 VVTMCIGGGQGAAGLFE 390
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
6-401 |
2.73e-67 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 218.42 E-value: 2.73e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 6 IIDAIRTPRGKGKkdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGdQGADIAKTAAIAAGWDNDVAGV 85
Cdd:PLN02644 5 IVGVARTPIGGFL--GSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVLSAN-LGQAPARQAALGAGLPPSTICT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 86 QINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMS-------------RVAMGS--DG----GAWafDPETNmacdfI 146
Cdd:PLN02644 82 TVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSnapkylpearkgsRLGHDTvvDGmlkdGLW--DVYND-----F 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 147 PQGIGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDQAG----VVILAQDEFIKpQTTAESLAQLKP 222
Cdd:PLN02644 155 GMGVCAELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEVPGGrgrpSVIVDKDEGLG-KFDPAKLRKLRP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 223 SFANMGqmgfdaialqkypeaGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPA 302
Cdd:PLN02644 234 SFKEDG---------------GSVT----AGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPA 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 303 PAARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRG 382
Cdd:PLN02644 295 LAIPKALKHAGLEASQVDYYEINEAFSVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGKYG 374
|
410
....*....|....*....
gi 1253006213 383 MATLCVGGGMGIATIIERV 401
Cdd:PLN02644 375 VAGICNGGGGASAIVVELM 393
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
3-401 |
1.08e-65 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 213.47 E-value: 1.08e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 3 EAYIIDAIRTPRGKgkKDGALHEVKPIRLLTTLLNELQQRHnldTSQVDDIVLGCVTpigDQGADIAKTAAIAAGWDNDV 82
Cdd:PRK06690 2 RAVIVEAKRTPIGK--KNGMLKDYEVQQLAAPLLTFLSKGM---EREIDDVILGNVV---GPGGNVARLSALEAGLGLHI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 83 AGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMGSDGgawAFDPETNMACDFipqGIGADLIATLDGYS 162
Cdd:PRK06690 74 PGVTIDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPFQNRA---RFSPETIGDPDM---GVAAEYVAERYNIT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 163 RTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDQAgvvilaqDEFIKPQTTAESLAQ-LKPSFANMGQMGfdaialqkyp 241
Cdd:PRK06690 148 REMQDEYACLSYKRTLQALEKGYIHEEILSFNGLL-------DESIKKEMNYERIIKrTKPAFLHNGTVT---------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 242 eagqvnhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPAARKALAKAGLNIEDIDL 321
Cdd:PRK06690 211 ----------AGNSCGVNDGACAVLVMEEGQARKLGYKPVLRFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDY 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 322 FEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRGMATLCVGGGMGIATIIERV 401
Cdd:PRK06690 281 FEINEAFASKVVACAKELQIPYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIATLGIGGGIGLALLFEKV 360
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
1-401 |
1.61e-60 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 200.62 E-value: 1.61e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKKdgALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGDqGADIAKTAAIAAGWDN 80
Cdd:PRK06366 1 MKDVYIVSAKRTAIGKFGR--SFSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAGV-GQNPAGQAAYHAGLPF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVA-MGSDGGAWA--------FDPETNMACD------- 144
Cdd:PRK06366 78 GVTKYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPfLLPSDLRWGpkhllhknYKIDDAMLVDglidafy 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 145 FIPQGIGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDqagvviLAQDEFIKpQTTAESLAQLKPSF 224
Cdd:PRK06366 158 FEHMGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFND------LDRDEGIR-KTTMEDLAKLPPAF 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 225 ANMGqmgfdaialqkypeagqvnhVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPAPA 304
Cdd:PRK06366 231 DKNG--------------------ILTAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIPA 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 305 ARKALAKAGLNIEDIDLFEVNEAF--AAVVLRfiTELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRG 382
Cdd:PRK06366 291 TRKLLEKQNKSIDYYDLVEHNEAFsiASIIVR--DQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKTG 368
|
410
....*....|....*....
gi 1253006213 383 MATLCVGGGMGIATIIERV 401
Cdd:PRK06366 369 LATLCHGGGGAHTLTLEMV 387
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
278-400 |
1.83e-54 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 176.29 E-value: 1.83e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 278 LKPRAKVLATALVGTDPAIMLTGPAPAARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGH 357
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1253006213 358 PLGATGAMILGTLLDELERQDKKRGMATLCVGGGMGIATIIER 400
Cdd:pfam02803 81 PLGASGARILVTLLHELKRRGGKYGLASLCIGGGQGVAMIIER 123
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
6-399 |
2.83e-54 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 184.71 E-value: 2.83e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 6 IIDAIRTPRGKGKkdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGdQGADIAKTAAIAAGWDNDVAGV 85
Cdd:PRK06954 11 IASAARTPMAAFQ--GEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLPAG-QGQAPARQAALGAGLPLSVGCT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 86 QINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMS-------------RVAMGS-------DGGAWAFDPETNMacdf 145
Cdd:PRK06954 88 TVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTnapyllpkarggmRMGHGQvldhmflDGLEDAYDKGRLM---- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 146 ipqGIGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVK--DQAGVVILAQDEfiKP-QTTAESLAQLKP 222
Cdd:PRK06954 164 ---GTFAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPVTvaGKKGDTVIDRDE--QPfKANPEKIPTLKP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 223 SFANMGQMGfdaialqkypeagqvnhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTDPAIMLTGPA 302
Cdd:PRK06954 239 AFSKTGTVT--------------------AANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPV 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 303 PAARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQDKKRG 382
Cdd:PRK06954 299 GAIRKLFEKNGWRAAEVDLFEINEAFAVVTMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGGKRG 378
|
410
....*....|....*..
gi 1253006213 383 MATLCVGGGMGIATIIE 399
Cdd:PRK06954 379 VASLCIGGGEATAMGIE 395
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
9-399 |
3.22e-50 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 173.83 E-value: 3.22e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 9 AIRTPRGK-GKKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGdQGADIAKTAAIAAGWDNDVAGVQI 87
Cdd:cd00826 3 AAMTAFGKfGGENGADANDLAHEAGAKAIAAALEPAGVAAGAVEEACLGQVLGAG-EGQNCAQQAAMHAGGLQEAPAIGM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 88 NRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMgSDGGAWAFDPETNMACdfipqgigadliatldgySRTEVD 167
Cdd:cd00826 82 NNLCGSGLRALALAMQLIAGGDANCILAGGFEKMETSAE-NNAKEKHIDVLINKYG------------------MRACPD 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 168 QFAAASQHKAAAAQAQGHFERSIVP--VKDQAGVVILAQDEFIKPQTTA--ESLAQLKPSFANMGQMGfdaialqkypea 243
Cdd:cd00826 143 AFALAGQAGAEAAEKDGRFKDEFAKfgVKGRKGDIHSDADEYIQFGDEAslDEIAKLRPAFDKEDFLT------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 244 gqvnhvhhAGNSSGIVDGAALVLIASEQAVQQHNLK-------PRAKVLATALVGTDPA----IMLTGPAPAARKALAKA 312
Cdd:cd00826 211 --------AGNACGLNDGAAAAILMSEAEAQKHGLQskareiqALEMITDMASTFEDKKvikmVGGDGPIEAARKALEKA 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 313 GLNIEDIDLFEVNEAFAAVVLRFITELQVDPAK------------------VNVNGGAIALGHPLGATGAMILGTLLDEL 374
Cdd:cd00826 283 GLGIGDLDLIEAHDAFAANACATNEALGLCPEGqggalvdrgdntyggksiINPNGGAIAIGHPIGASGAAICAELCFEL 362
|
410 420 430
....*....|....*....|....*....|
gi 1253006213 375 ERQDKKR-----GMATLCVGGGMGIATIIE 399
Cdd:cd00826 363 KGEAGKRqgagaGLALLCIGGGGGAAMCIE 392
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
6-400 |
9.55e-46 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 162.85 E-value: 9.55e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 6 IIDAIRTPRGKgkKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIgDQGADIAKTAAIAAGWDNDVAGV 85
Cdd:PRK08963 9 IVSGLRTPFAK--QATAFHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQM-PEAPNIAREIVLGTGMNVHTDAY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 86 QINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRVAMG-SDGGAWAFdPETNMA---------------CDFIPQ- 148
Cdd:PRK08963 86 SVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGvSKKLARAL-VDLNKArtlgqrlklfsrlrlRDLLPVp 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 149 ------------GIGADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSI----VPVKDQAgvviLAQDEFIKPQT 212
Cdd:PRK08963 165 pavaeystglrmGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEVmtahVPPYKQP----LEEDNNIRGDS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 213 TAESLAQLKPSFAnmgqmgfdaialQKYpeaGQVNhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGT 292
Cdd:PRK08963 241 TLEDYAKLRPAFD------------RKH---GTVT----AANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAI 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 293 DP-AIMLTGPAPAARKALAKAGLNIEDIDLFEVNEAFAAVVL---------RFITEL--------QVDPAKVNVNGGAIA 354
Cdd:PRK08963 302 DVwQDMLLGPAYATPLALERAGLTLADLTLIDMHEAFAAQTLanlqmfaseRFAREKlgrsqaigEVDMSKFNVLGGSIA 381
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 1253006213 355 LGHPLGATGA-MILGTlLDELERQDKKRGMATLCVGGGMGIATIIER 400
Cdd:PRK08963 382 YGHPFAATGArMITQT-LHELRRRGGGLGLTTACAAGGLGAAMVLEV 427
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
5-271 |
1.09e-44 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 155.54 E-value: 1.09e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 5 YIIDAIRTPRGKGKkdGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIGdQGADIAKTAAIAAGWDNDVAG 84
Cdd:pfam00108 2 VIVSAARTPFGSFG--GSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAG-EGQNPARQAALKAGIPDSAPA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 85 VQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRV--AMGSDGGAWAFDPETNM-----------ACDFIPQGIG 151
Cdd:pfam00108 79 VTINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHApyALPTDARSGLKHGDEKKhdllipdgltdAFNGYHMGLT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 152 ADLIATLDGYSRTEVDQFAAASQHKAAAAQAQGHFERSIVPV--KDQAGVVILAQDEFIKPQTTAESLAQLKPSFANMGQ 229
Cdd:pfam00108 159 AENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVtvKGRKGKPTVDKDEGIRPPTTAEPLAKLKPAFDKEGT 238
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1253006213 230 MgfdaialqkypeagqvnhvhHAGNSSGIVDGAALVLIASEQ 271
Cdd:pfam00108 239 V--------------------TAGNASPINDGAAAVLLMSES 260
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
31-400 |
6.55e-40 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 146.97 E-value: 6.55e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 31 LLTTLLNELQQRHNLDTSQVDDIVLGCVTpigDQGAD--IAKTAAIAAGWDNDVAGVQINRFCASGLEAVNLAAQKVRSG 108
Cdd:PRK09268 34 MLTAALDGLVDRFGLQGERLGEVVAGAVL---KHSRDfnLTRECVLGSALSPYTPAYDLQQACGTGLEAAILVANKIALG 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 109 WEDLIVAGGVESMSRVAMGSDGGAWAFDPETNMA---------------CDFIPQ-------------GIGADLIATLDG 160
Cdd:PRK09268 111 QIDSGIAGGVDTTSDAPIAVNEGLRKILLELNRAkttgdrlkalgklrpKHLAPEiprngeprtglsmGEHAAITAKEWG 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 161 YSRTEVDQFAAASQHKAAAAQAQGHFERSIVPVKDqagvviLAQDEFIKPQTTAESLAQLKPSF--ANMGQMGfdaialq 238
Cdd:PRK09268 191 ISREAQDELAAASHQNLAAAYDRGFFDDLITPFLG------LTRDNNLRPDSSLEKLAKLKPVFgkGGRATMT------- 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 239 kypeagqvnhvhhAGNSSGIVDGAALVLIASEQAVQQHNLKPRAKVLA--TALV----GTDPaiMLTGPAPAARKALAKA 312
Cdd:PRK09268 258 -------------AGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDaeTAAVdfvhGKEG--LLMAPAYAVPRLLARN 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 313 GLNIEDIDLFEVNEAFAAVVLrfiTELQ--------------------VDPAKVNVNGGAIALGHPLGATGAMILGTLLD 372
Cdd:PRK09268 323 GLTLQDFDFYEIHEAFASQVL---ATLKawedeeycrerlgldaplgsIDRSKLNVNGSSLAAGHPFAATGGRIVATLAK 399
|
410 420
....*....|....*....|....*...
gi 1253006213 373 ELERQDKKRGMATLCVGGGMGIATIIER 400
Cdd:PRK09268 400 LLAEKGSGRGLISICAAGGQGVTAILER 427
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
231-398 |
1.04e-20 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 90.58 E-value: 1.04e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 231 GFDAIAL-QKYPEAGQVNHVHHAG-NSSGIVDGAALVLIASEQAVQQHNLKPRAKVLATALVGTD----PAIMLTGPAPA 304
Cdd:cd00327 71 GLTALALaVQQVQNGKADIVLAGGsEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAATFDGasmvPAVSGEGLARA 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 305 ARKALAKAGLNIEDIDLFEVNEAFAAVVLRFITELQVDPAKV---NVNGGAIALGHPLGATGAMILGTLLDELERQDKKR 381
Cdd:cd00327 151 ARKALEGAGLTPSDIDYVEAHGTGTPIGDAVELALGLDPDGVrspAVSATLIMTGHPLGAAGLAILDELLLMLEHEFIPP 230
|
170 180
....*....|....*....|....
gi 1253006213 382 -------GMATLCVGGGMGIATII 398
Cdd:cd00327 231 tpreprtVLLLGFGLGGTNAAVVL 254
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
44-398 |
2.54e-16 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 79.61 E-value: 2.54e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 44 NLDTSQVDDIVLGCVTPIGDQGaDIAKTAAIAAGWDNdVAGVQINRFCASGLEAVNLAAQKVRSGWEDLIVAGGVESMSR 123
Cdd:cd00829 32 GLEPADIDAVVVGNAAGGRFQS-FPGALIAEYLGLLG-KPATRVEAAGASGSAAVRAAAAAIASGLADVVLVVGAEKMSD 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 124 VAMGSDGGAWAFDPEtnmacDFIPQGIGADLIATLDGYSRTEvdqfaaasqhkaaaaqaqgHFERSIVPVKDQAGVVIL- 202
Cdd:cd00829 110 VPTGDEAGGRASDLE-----WEGPEPPGGLTPPALYALAARR-------------------YMHRYGTTREDLAKVAVKn 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 203 ---------AQdeFIKPQTTAESLAQlkpsfanmgQMGFDAIalqkypeagqvnhvhHAGNSSGIVDGAALVLIASEQAV 273
Cdd:cd00829 166 hrnaarnpyAQ--FRKPITVEDVLNS---------RMIADPL---------------RLLDCCPVSDGAAAVVLASEERA 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 274 QQHNLKPrAKVLATAlVGTDPA--------IMLTGPAPAARKALAKAGLNIEDIDLFEVNEAFAAVVL------------ 333
Cdd:cd00829 220 RELTDRP-VWILGVG-AASDTPslserddfLSLDAARLAARRAYKMAGITPDDIDVAELYDCFTIAELlaledlgfcekg 297
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1253006213 334 ---RFITELQVDP---AKVNVNGGAIALGHPLGATGAMILGTLLDEL-----ERQDKKRGMATLCVGGGMGIATII 398
Cdd:cd00829 298 eggKLVREGDTAIggdLPVNTSGGLLSKGHPLGATGLAQAVEAVRQLrgeagARQVPGARVGLAHNIGGTGSAAVV 373
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
91-401 |
5.92e-11 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 63.38 E-value: 5.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 91 CASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRV-------AMGSDGGA-WafdpETNMACDFIpqGIGAdLIATL--DG 160
Cdd:PRK06064 85 CASGGAALRQAYLAVASGEADVVLAAGVEKMTDVptpdateAIARAGDYeW----EEFFGATFP--GLYA-LIARRymHK 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 161 YSRTEVDQfaaasqhkaaaaqaqghferSIVPVKDQAGVVIlaqdefikpqttaESLAQLKpsfanmgqmgfDAIALQKY 240
Cdd:PRK06064 158 YGTTEEDL--------------------ALVAVKNHYNGSK-------------NPYAQFQ-----------KEITVEQV 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 241 PEAGQVNHVHHAGNSSGIVDGAALVLIASEQAVQQHNLKPrAKVLATAlVGTDPAI------MLTGPAP--AARKALAKA 312
Cdd:PRK06064 194 LNSPPVADPLKLLDCSPITDGAAAVILASEEKAKEYTDTP-VWIKASG-QASDTIAlhdrkdFTTLDAAvvAAEKAYKMA 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 313 GLNIEDIDLFEVNEAF--AAVV----LRFI-------------TELQVDPAkVNVNGGAIALGHPLGATG----AMILGT 369
Cdd:PRK06064 272 GIEPKDIDVAEVHDCFtiAEILayedLGFAkkgeggklaregqTYIGGDIP-VNPSGGLKAKGHPVGATGvsqaVEIVWQ 350
|
330 340 350
....*....|....*....|....*....|....*...
gi 1253006213 370 LLDELE---RQDKKRGMA-TLCVGGGMGIA--TIIERV 401
Cdd:PRK06064 351 LRGEAEkgrQQVIGAGYGlTHNVGGTGHTAvvHILSRK 388
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
260-363 |
2.21e-08 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 55.67 E-value: 2.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 260 DGAALVLIASEQAVQQHNLKPRAKVLATALVgTDPAIMLTGPAP-----------AARKALAKAGLNIEDIDLFEVNEAF 328
Cdd:PRK08256 215 CGAAAAIVCSEEFARKHGLDRAVEIVAQAMT-TDTPSTFDGRSMidlvgydmtraAAQQVYEQAGIGPEDIDVVELHDCF 293
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1253006213 329 AAVVLrfIT-------------ELQVDPAK-------VNVNGGAIALGHPLGATG 363
Cdd:PRK08256 294 SANEL--LTyealglcpegeaeKFIDDGDNtyggrwvVNPSGGLLSKGHPLGATG 346
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
256-363 |
1.41e-07 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 53.36 E-value: 1.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 256 SGIVDGAALVLIASEQAVQQHNLKP------RAKVLATALVG-----TDPAIMLTGPApAARKALAKAGLNIEDIDLFEV 324
Cdd:PTZ00455 256 SQVSDGGAGLVLASEEGLQKMGLSPndsrlvEIKSLACASGNlyedpPDATRMFTSRA-AAQKALSMAGVKPSDLQVAEV 334
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1253006213 325 NEAFAAVVLRFITELQV-DPAK-----------------VNVNGGAIALGHPLGATG 363
Cdd:PTZ00455 335 HDCFTIAELLMYEALGIaEYGHakdlirngatalegripVNTGGGLLSFGHPVGATG 391
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
91-366 |
1.79e-07 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 52.93 E-value: 1.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 91 CASGLEAVNLAAQKVRSGWEDLIVAGGVESMSRV------AMGSDGGAWAFdpETNMACDFIPQGIGADLIATLDGYSRT 164
Cdd:PRK12578 82 CATGLAASLTAYTAVASGLVDMAIAVGVDKMTEVdtstslAIGGRGGNYQW--EYHFYGTTFPTYYALYATRHMAVYGTT 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 165 EVDQfaaasqhkaaaaqaqghferSIVPVKDQAGVVILAQDEFIKPQTTAESLAQLKPSFAnmgqmgfdaIALQkypeag 244
Cdd:PRK12578 160 EEQM--------------------ALVSVKAHKYGAMNPKAHFQKPVTVEEVLKSRAISWP---------IKLL------ 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 245 qvnhvhhagNSSGIVDGAALVLIASEQAVQQhnLKPRAKVLATAL-VGTDPAIM--------LTGPAPAARKALAKAGLN 315
Cdd:PRK12578 205 ---------DSCPISDGSATAIFASEEKVKE--LKIDSPVWITGIgYANDYAYVarrgewvgFKATQLAARQAYNMAKVT 273
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 316 IEDIDLFEVNEAFAAVVL---------------RFITELQVDP-AKVNVN--GGAIALGHPLGATG-AMI 366
Cdd:PRK12578 274 PNDIEVATVHDAFTIAEImgyedlgftekgkggKFIEEGQSEKgGKVGVNlfGGLKAKGHPLGATGlSMI 343
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
256-401 |
1.08e-05 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 47.25 E-value: 1.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 256 SGIVDGAALVLIASEQAVQQhnLKPRAKVLATALVGT-------DPaIMLTGPAPAARKALAKAGLNIEDIDLFEVNEAF 328
Cdd:PRK07516 213 SLVSDGAAALVLADAETARA--LQRAVRFRARAHVNDflplsrrDP-LAFEGPRRAWQRALAQAGVTLDDLSFVETHDCF 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 329 AAVVL---------------RFITELQVDPA---KVNVNGGAIALGHPLGATG-------AMILGTLLDELERQDKKRG- 382
Cdd:PRK07516 290 TIAELieyeamglappgqgaRAIREGWTAKDgklPVNPSGGLKAKGHPIGATGvsmhvlaAMQLTGEAGGMQIPGAKLAg 369
|
170 180
....*....|....*....|....*
gi 1253006213 383 ---MatlcvgGGMGIA---TIIERV 401
Cdd:PRK07516 370 vfnM------GGAAVAnyvSILERV 388
|
|
| PRK05952 |
PRK05952 |
beta-ketoacyl-ACP synthase; |
260-377 |
1.25e-05 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235653 [Multi-domain] Cd Length: 381 Bit Score: 46.97 E-value: 1.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 260 DGAALVLIASEQAVQQHNLKPRAKVLATALvgTDPAIMLTGPAP-------AARKALAKAGLNIEDIDLF-------EVN 325
Cdd:PRK05952 210 EGGAILVLESAELAQKRGAKIYGQILGFGL--TCDAYHMSAPEPdgksaiaAIQQCLARSGLTPEDIDYIhahgtatRLN 287
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1253006213 326 EAFAAVVLRfitelQVDPAKVNVNGGAIALGHPLGATGAMILGTLLDELERQ 377
Cdd:PRK05952 288 DQREANLIQ-----ALFPHRVAVSSTKGATGHTLGASGALGVAFSLLALRHQ 334
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
256-367 |
2.87e-05 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 45.83 E-value: 2.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 256 SGIVDGAALVLIASEQAVQQHnlkPRAKVLA--------TALVGTDPAIMLTGPAP--------AARKALAKAGLNIEDI 319
Cdd:PRK06289 220 SQVTDGGAGVVLASDAYLRDY---ADARPIPrikgwghrTAPLGLEQKLDRSAGDPyvlphvrqAVLDAYRRAGVGLDDL 296
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1253006213 320 DLFEVNEAFAAVVL---------------RFITELQVDPA---KVNVNGGAIALGHPLGATGAMIL 367
Cdd:PRK06289 297 DGFEVHDCFTPSEYlaidhigltgpgeswKAIENGEIAIGgrlPINPSGGLIGGGHPVGASGVRML 362
|
|
| PRK06066 |
PRK06066 |
thiolase domain-containing protein; |
256-391 |
1.94e-04 |
|
thiolase domain-containing protein;
Pssm-ID: 180380 [Multi-domain] Cd Length: 385 Bit Score: 43.20 E-value: 1.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 256 SGIVDGAALVLIASEQAVQQHNLKP---RAKVLATALVGTDPAIMltGPAPAARKA--LAK--AGLN--IEDIDLFEVNE 326
Cdd:PRK06066 208 APFVDGAIVVVLASEEVAKKLTDDPvwiKGIGWSTESSNLETAEL--GKANYMRIAadMAYkmAGIEspRKEVDAAEVDD 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 327 AFAAVVLRFITELQVDPA------------------KVNVNGGAIALGHPLGATGamiLGTLLDELERQdkkRGMATLCV 388
Cdd:PRK06066 286 RYSYKELQHIEALRLSEEpekdsllregnfdpqgelPVNPSGGHLAKGVPLEASG---LSLLLDAVEYL---RGEAGARQ 359
|
...
gi 1253006213 389 GGG 391
Cdd:PRK06066 360 GKA 362
|
|
| PRK06365 |
PRK06365 |
thiolase domain-containing protein; |
260-399 |
3.81e-04 |
|
thiolase domain-containing protein;
Pssm-ID: 235785 [Multi-domain] Cd Length: 430 Bit Score: 42.59 E-value: 3.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 260 DGAALVLIASEQAVQQHNLKP-RAKVLATALVGTDPAIMLTGPAP--------------------------AARKALAKA 312
Cdd:PRK06365 227 DGAACAILASEDKAFEITDKPvLIKAIGTGSDTLRLADRPFGEVPllpnespddykdlrypgvhsfragrmAAKEAYEMA 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 313 GLN--IEDIDLFEVNEAFAAVVLRFITELQ----------VDPAK--------VNVNGGAIALGHPLGATGAM------- 365
Cdd:PRK06365 307 GITdpLNDLDLIELHDAYTSSEIQTYEDLGlckygeggqfIESGKpelpgklpVNPSGGLLAAGHAVGATGIMqavfmfw 386
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1253006213 366 -ILGTL-----LDELERQDKKRGMATLCVGGGMGI-ATIIE 399
Cdd:PRK06365 387 qLQGRIkkhfhDDYLQVKNAKRGLIHSHAGTGTYVtVTILE 427
|
|
| ketoacyl-synt |
pfam00109 |
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
91-137 |
4.43e-04 |
|
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains. The N-terminal domain contains most of the structures involved in dimer formation and also the active site cysteine.
Pssm-ID: 425468 [Multi-domain] Cd Length: 251 Bit Score: 41.47 E-value: 4.43e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1253006213 91 CASGLEAVNLAAQKVRSGWEDLIVAGGVESM---------SRVAMGSDGG-AWAFDP 137
Cdd:pfam00109 173 CSSSLVAIHAAVQSIRSGEADVALAGGVNLLltplgfagfSAAGMLSPDGpCKAFDP 229
|
|
| PRK07103 |
PRK07103 |
polyketide beta-ketoacyl:acyl carrier protein synthase; Validated |
216-320 |
1.02e-03 |
|
polyketide beta-ketoacyl:acyl carrier protein synthase; Validated
Pssm-ID: 180839 [Multi-domain] Cd Length: 410 Bit Score: 41.17 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 216 SLAQLKP----SFANMGQMGFDAIALQkyPEAGQVNHVHhagNSSGIVDG--AALVLIASEQAVQQHNLKPRAKVLATAL 289
Cdd:PRK07103 194 ALMDLSYwecqALRSLGAMGSDRFADE--PEAACRPFDQ---DRDGFIYGeaCGAVVLESAESARRRGARPYAKLLGWSM 268
|
90 100 110
....*....|....*....|....*....|....*.
gi 1253006213 290 V-----GTDPAimLTGPAPAARKALAKAGLNIEDID 320
Cdd:PRK07103 269 RldanrGPDPS--LEGEMRVIRAALRRAGLGPEDID 302
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
302-393 |
1.59e-03 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 40.09 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 302 APAARKALAKAGLNIEDIDLF---EVNEAFAAVVLRfitELQVDPAKVNVNggaIA-LGHplgaTGAMILGTLLDELERQ 377
Cdd:COG0332 227 PEVIREALEKAGLTLDDIDWFiphQANLRIIEAVAK---RLGLPEEKVVVN---IDrYGN----TSAASIPLALDEALRE 296
|
90
....*....|....*..
gi 1253006213 378 DK-KRGMATLCVGGGMG 393
Cdd:COG0332 297 GRiKPGDLVLLAGFGAG 313
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
1-132 |
2.28e-03 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 39.72 E-value: 2.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 1 MSEAYIIDAIRTPRGKGKKDGALHEVKPIRLLTTLLNELQQRHNLDTSQVDDIVLGCVTPIgDQGADIAKTAAIAAGwDN 80
Cdd:cd00827 21 LAEGLGVDPGKYTTGIGQRHMAGDDEDVPTMAVEAARRALERAGIDPDDIGLLIVATESPI-DKGKSAATYLAELLG-LT 98
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 81 DVAGVQINRFCASGLEAVNLAAQKVRSG-WED-LIVAGGV------ESMSRVAMGSDGGA 132
Cdd:cd00827 99 NAEAFDLKQACYGGTAALQLAANLVESGpWRYaLVVASDIasylldEGSALEPTLGDGAA 158
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
91-122 |
7.19e-03 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 38.29 E-value: 7.19e-03
10 20 30
....*....|....*....|....*....|..
gi 1253006213 91 CASGLEAVNLAAQKVRSGWEDLIVAGGVESMS 122
Cdd:cd00834 161 CASGAHAIGDAARLIRLGRADVVIAGGAEALI 192
|
|
| PRK06158 |
PRK06158 |
thiolase; Provisional |
261-401 |
7.53e-03 |
|
thiolase; Provisional
Pssm-ID: 180434 [Multi-domain] Cd Length: 384 Bit Score: 38.09 E-value: 7.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1253006213 261 GAALVLIASEQAVQQHnlKPRAKVLATAL------VGTDPAIMLTGPAPAARKALAKAGLNIEDIDLFEVNEAFAAVVLR 334
Cdd:PRK06158 212 AGAVVMVRADRARDLP--RPPVYVLGAAAatwhrqISSMPDLTVTAAAESGPRAFAMAGLTPADIDVVELYDAFTINTIL 289
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1253006213 335 FITELQVDP---AKVNVNGGAIALGhplgatGAMILGTlldelerqdkkRGMATLCVGGGM-GIATIIERV 401
Cdd:PRK06158 290 FLEDLGFCAkgeGGAFVEGGRIAPG------GRLPVNT-----------NGGGLSCVHPGMyGLFLLIEAV 343
|
|
| |
