|
Name |
Accession |
Description |
Interval |
E-value |
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
2-458 |
0e+00 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 592.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 2 INRTLKQVEQMVNGTGLAEqyEGITIQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLWMKDVanpPENL 81
Cdd:COG0770 1 ILLTLAEIAEATGGRLIGD--PDLVVTGVSTDSRKIKPGDLFVALKGERFDGHDFVAQALAKGAAAALVSRPL---PADL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 82 PVIFVEDTLSALQMLAKNYRNQLDVKVIGVTGSNGKTSTKDIVTSLLATKFKVQKTEGNFNNHIGLPLTILNLEENTEVA 161
Cdd:COG0770 76 PLIVVDDTLKALQQLAAAHRARFNIPVIAITGSNGKTTTKEMLAAVLSTKGKVLATPGNFNNEIGVPLTLLRLPEDHEFA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 162 VLEMGMSSRGEIEFLSKLARPNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNRVPKMNliA 241
Cdd:COG0770 156 VLEMGMNHPGEIAYLARIARPDIAVITNIGPAHLEGFGSLEGIARAKGEIFEGLPPGGVAVLNADDPLLAALAERAK--A 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 242 ETVTFGDARANDYYPTTVALQATGTHFKMN-RDENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMTGM 320
Cdd:COG0770 234 RVLTFGLSEDADVRAEDIELDEDGTRFTLHtPGGELEVTLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLAAFQPVKG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 321 RMEIVKTDSGLTIINDAYNASPTAMEAAFHLMNGLDGFAKKIVVLGDMLELGNQEVQFHYEVGKLIDPAKIAYVFTYGKL 400
Cdd:COG0770 314 RLEVIEGAGGVTLIDDSYNANPDSMKAALDVLAQLPGGGRRIAVLGDMLELGEESEELHREVGELAAELGIDRLFTVGEL 393
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 1264383898 401 GAQIAEGakinFPIERVKAYDNKEELVKELQAVVDVKDVVLIKASRGMKLEEVITMLK 458
Cdd:COG0770 394 ARAIAEA----AGGERAEHFEDKEELLAALKALLRPGDVVLVKGSRGMGLERVVEALK 447
|
|
| murF |
TIGR01143 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the ... |
32-457 |
2.62e-155 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the strictly bacterial MurF gene of peptidoglycan biosynthesis. This enzyme is almost always UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, but in a few species, MurE adds lysine rather than diaminopimelate. This enzyme acts on the product from MurE activity, and so is also subfamily rather than equivalog. Staphylococcus aureus is an example of species in this MurF protein would differ. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273468 [Multi-domain] Cd Length: 417 Bit Score: 446.71 E-value: 2.62e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 32 IDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLWMKDVaNPPENLPVIFVEDTLSALQMLAKNYRNQLDVKVIGV 111
Cdd:TIGR01143 1 TDSRAIKPGDLFIALKGERFDGHDFVEQALAAGAVAVVVDREV-GPDNGLPQILVDDTLEALQALARAKRAKFSGKVIGI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 112 TGSNGKTSTKDIVTSLLATKFKVQKTEGNFNNHIGLPLTILNLEENTEVAVLEMGMSSRGEIEFLSKLARPNAAIITNIG 191
Cdd:TIGR01143 80 TGSSGKTTTKEMLAAILSHKYKVFATPGNFNNEIGLPLTLLRAPGDHDYAVLEMGASHPGEIAYLAEIAKPDIAVITNIG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 192 EAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLtNRVPKMNLIAETVTFGDARAnDYYPTTVALQATG-THFKM 270
Cdd:TIGR01143 160 PAHLEGFGSLEGIAEAKGEILQGLKENGIAVINADDPAF-ADLAKRLPNRNILSFGFEGG-DFVAKDISYSALGsTSFTL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 271 N-RDENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMTGMRMEIvKTDSGLTIINDAYNASPTAMEAAF 349
Cdd:TIGR01143 238 VaPGGEFEVSLPLLGRHNVMNALAAAALALELGIPLEEIAEGLAELKLVKGRFEV-QTKNGLTLIDDTYNANPDSMRAAL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 350 HLMNGLDGfaKKIVVLGDMLELGNQEVQFHYEVGKLIDPAKIAYVFTYGKLGAQIAEGAKinfpiERVKAYDNKEELVKE 429
Cdd:TIGR01143 317 DALARFPG--KKILVLGDMAELGEYSEELHAEVGRYANSLGIDLVFLVGEEAAVIYDSFG-----KQGKHFADKDELLAF 389
|
410 420
....*....|....*....|....*...
gi 1264383898 430 LQAVVDVKDVVLIKASRGMKLEEVITML 457
Cdd:TIGR01143 390 LKTLVRKGDVVLVKGSRSVKLEKVVEAL 417
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
13-458 |
4.28e-124 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 383.67 E-value: 4.28e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 13 VNGTGLAEQYEGITIQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLwmkdVANP--PENLPVIFVEDTL 90
Cdd:PRK11929 512 KGGSNSLQINSLPHAGAVSTDSRSVGRGELFVALRGENFDGHDYLPQAFAAGACAAV----VERQvaDVDLPQIVVDDTR 587
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 91 SALQMLAKNYRNQLDVKVIGVTGSNGKTSTKDIVTSLLAT---KFKVQKTEGNFNNHIGLPLTILNLEENTEVAVLEMGM 167
Cdd:PRK11929 588 AALGRLATAWRARFSLPVVAITGSNGKTTTKEMIAAILAAwqgEDRVLATEGNFNNEIGVPLTLLRLRAQHRAAVFELGM 667
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 168 SSRGEIEFLSKLARPNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPlLTNRVPKMNLIAETVTFG 247
Cdd:PRK11929 668 NHPGEIAYLAAIAAPTVALVTNAQREHQEFMHSVEAVARAKGEIIAALPEDGVAVVNGDDP-YTAIWAKLAGARRVLRFG 746
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 248 -----DARANDYYPTTVALQATGTHFKMNRD-ENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMTGMR 321
Cdd:PRK11929 747 lqpgaDVYAEKIAKDISVGEAGGTRCQVVTPaGSAEVYLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQPVAGR 826
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 322 MEIVKTDSGLTIINDAYNASPTAMEAAFHLMNGLDGfAKKIVVLGDMLELGNQEVQFHYEVGKLIDPAKIAYVFTYGKLG 401
Cdd:PRK11929 827 MQRRRLSCGTRIIDDTYNANPDSMRAAIDVLAELPN-GPRALVLGDMLELGDNGPAMHREVGKYARQLGIDALITLGEAA 905
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1264383898 402 AQIAEgakiNFPIERVKAYDNKEELVKELQAVVDVKDVVLIKASRGMKLEEVITMLK 458
Cdd:PRK11929 906 RDAAA----AFGAGARGVCASVDEIIAALRGALPEGDSVLIKGSRFMRLERVVDALS 958
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
111-298 |
7.71e-51 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 170.95 E-value: 7.71e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 111 VTGSNGKTSTKDIVTSLLATKFKVQKTEG--------NFNNHIGLPLTILNL-EENTEVAVLEMGMSSRGEiEFLSKLAR 181
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGGVIGTIGtyigksgnTTNNAIGLPLTLAEMvEAGAEYAVLEVSSHGLGE-GRLSGLLK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 182 PNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNRVPKM-NLIAETVTFGDARANDYYPTTVA 260
Cdd:pfam08245 80 PDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPYGAFLIAKLkKAGVRVITYGIEGEADLRAANIE 159
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1264383898 261 LQATGTHFKMN--RDENISFYLPVLGKHNVYNTLASMAIA 298
Cdd:pfam08245 160 LSSDGTSFDLFtvPGGELEIEIPLLGRHNVYNALAAIAAA 199
|
|
| F430_CfbE |
NF033197 |
coenzyme F430 synthase; Members of this family are coenzyme F430 synthase, involving in ... |
77-337 |
3.80e-09 |
|
coenzyme F430 synthase; Members of this family are coenzyme F430 synthase, involving in synthesizing coenzyme F430, which is used in methanogens by coenzyme M reductase. Members of this family are restricted to archaeal methanogens, and resemble (and may be misannotated as) MurD, an enzyme of bacterial cell wall biosynthesis.
Pssm-ID: 467992 [Multi-domain] Cd Length: 419 Bit Score: 58.49 E-value: 3.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 77 PPENLPVIFVEDtlsALQMLAKNYRNQLDVKVIGVTGSNGKTSTKDIVTSLLATKFKVQKT--------EGNFNNHIGL- 147
Cdd:NF033197 66 PPDGKPFITHHE---AVGEILKKKYGRIPKKFIEITGVKGKTTTAELLAHILSDEYVLLHTsrgterypEGELSNKGSIt 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 148 PLTILNLEENTEvavlEMGMSSRGEIEF---LSKLARPNAAIITNIGEAHLMDLGSREAIAeAKLEIVTGLQEGGVFV-- 222
Cdd:NF033197 143 PASILNALELAE----EIGIDDYGFLIFevsLGGTGAGDVGIITNILEDYPIAGGKRSASA-AKLQSLKNAKVGSINVad 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 223 ---YNGDEPLLTNRVPKmnliAETVTFGDARANDyypttvalqatgthfkmnRDENISFYLPVLGKHNVYNTLASMAIAK 299
Cdd:NF033197 218 lgiYINGKNKLVITVAG----VEILSKYPLRFKY------------------GNTEFEFNPLLFGPHYRENSLFAIEAAL 275
|
250 260 270
....*....|....*....|....*....|....*...
gi 1264383898 300 HFGVTWEEMKQGLVTLQMTGMRMEIVKTDsGLTIINDA 337
Cdd:NF033197 276 NLGVDPEDIISALKGFKGLPGRMAVKKEG-GVVIVDNI 312
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
2-458 |
0e+00 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 592.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 2 INRTLKQVEQMVNGTGLAEqyEGITIQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLWMKDVanpPENL 81
Cdd:COG0770 1 ILLTLAEIAEATGGRLIGD--PDLVVTGVSTDSRKIKPGDLFVALKGERFDGHDFVAQALAKGAAAALVSRPL---PADL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 82 PVIFVEDTLSALQMLAKNYRNQLDVKVIGVTGSNGKTSTKDIVTSLLATKFKVQKTEGNFNNHIGLPLTILNLEENTEVA 161
Cdd:COG0770 76 PLIVVDDTLKALQQLAAAHRARFNIPVIAITGSNGKTTTKEMLAAVLSTKGKVLATPGNFNNEIGVPLTLLRLPEDHEFA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 162 VLEMGMSSRGEIEFLSKLARPNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNRVPKMNliA 241
Cdd:COG0770 156 VLEMGMNHPGEIAYLARIARPDIAVITNIGPAHLEGFGSLEGIARAKGEIFEGLPPGGVAVLNADDPLLAALAERAK--A 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 242 ETVTFGDARANDYYPTTVALQATGTHFKMN-RDENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMTGM 320
Cdd:COG0770 234 RVLTFGLSEDADVRAEDIELDEDGTRFTLHtPGGELEVTLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLAAFQPVKG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 321 RMEIVKTDSGLTIINDAYNASPTAMEAAFHLMNGLDGFAKKIVVLGDMLELGNQEVQFHYEVGKLIDPAKIAYVFTYGKL 400
Cdd:COG0770 314 RLEVIEGAGGVTLIDDSYNANPDSMKAALDVLAQLPGGGRRIAVLGDMLELGEESEELHREVGELAAELGIDRLFTVGEL 393
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 1264383898 401 GAQIAEGakinFPIERVKAYDNKEELVKELQAVVDVKDVVLIKASRGMKLEEVITMLK 458
Cdd:COG0770 394 ARAIAEA----AGGERAEHFEDKEELLAALKALLRPGDVVLVKGSRGMGLERVVEALK 447
|
|
| murF |
TIGR01143 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the ... |
32-457 |
2.62e-155 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the strictly bacterial MurF gene of peptidoglycan biosynthesis. This enzyme is almost always UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, but in a few species, MurE adds lysine rather than diaminopimelate. This enzyme acts on the product from MurE activity, and so is also subfamily rather than equivalog. Staphylococcus aureus is an example of species in this MurF protein would differ. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273468 [Multi-domain] Cd Length: 417 Bit Score: 446.71 E-value: 2.62e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 32 IDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLWMKDVaNPPENLPVIFVEDTLSALQMLAKNYRNQLDVKVIGV 111
Cdd:TIGR01143 1 TDSRAIKPGDLFIALKGERFDGHDFVEQALAAGAVAVVVDREV-GPDNGLPQILVDDTLEALQALARAKRAKFSGKVIGI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 112 TGSNGKTSTKDIVTSLLATKFKVQKTEGNFNNHIGLPLTILNLEENTEVAVLEMGMSSRGEIEFLSKLARPNAAIITNIG 191
Cdd:TIGR01143 80 TGSSGKTTTKEMLAAILSHKYKVFATPGNFNNEIGLPLTLLRAPGDHDYAVLEMGASHPGEIAYLAEIAKPDIAVITNIG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 192 EAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLtNRVPKMNLIAETVTFGDARAnDYYPTTVALQATG-THFKM 270
Cdd:TIGR01143 160 PAHLEGFGSLEGIAEAKGEILQGLKENGIAVINADDPAF-ADLAKRLPNRNILSFGFEGG-DFVAKDISYSALGsTSFTL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 271 N-RDENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMTGMRMEIvKTDSGLTIINDAYNASPTAMEAAF 349
Cdd:TIGR01143 238 VaPGGEFEVSLPLLGRHNVMNALAAAALALELGIPLEEIAEGLAELKLVKGRFEV-QTKNGLTLIDDTYNANPDSMRAAL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 350 HLMNGLDGfaKKIVVLGDMLELGNQEVQFHYEVGKLIDPAKIAYVFTYGKLGAQIAEGAKinfpiERVKAYDNKEELVKE 429
Cdd:TIGR01143 317 DALARFPG--KKILVLGDMAELGEYSEELHAEVGRYANSLGIDLVFLVGEEAAVIYDSFG-----KQGKHFADKDELLAF 389
|
410 420
....*....|....*....|....*...
gi 1264383898 430 LQAVVDVKDVVLIKASRGMKLEEVITML 457
Cdd:TIGR01143 390 LKTLVRKGDVVLVKGSRSVKLEKVVEAL 417
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
13-458 |
4.28e-124 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 383.67 E-value: 4.28e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 13 VNGTGLAEQYEGITIQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLwmkdVANP--PENLPVIFVEDTL 90
Cdd:PRK11929 512 KGGSNSLQINSLPHAGAVSTDSRSVGRGELFVALRGENFDGHDYLPQAFAAGACAAV----VERQvaDVDLPQIVVDDTR 587
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 91 SALQMLAKNYRNQLDVKVIGVTGSNGKTSTKDIVTSLLAT---KFKVQKTEGNFNNHIGLPLTILNLEENTEVAVLEMGM 167
Cdd:PRK11929 588 AALGRLATAWRARFSLPVVAITGSNGKTTTKEMIAAILAAwqgEDRVLATEGNFNNEIGVPLTLLRLRAQHRAAVFELGM 667
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 168 SSRGEIEFLSKLARPNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPlLTNRVPKMNLIAETVTFG 247
Cdd:PRK11929 668 NHPGEIAYLAAIAAPTVALVTNAQREHQEFMHSVEAVARAKGEIIAALPEDGVAVVNGDDP-YTAIWAKLAGARRVLRFG 746
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 248 -----DARANDYYPTTVALQATGTHFKMNRD-ENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMTGMR 321
Cdd:PRK11929 747 lqpgaDVYAEKIAKDISVGEAGGTRCQVVTPaGSAEVYLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQPVAGR 826
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 322 MEIVKTDSGLTIINDAYNASPTAMEAAFHLMNGLDGfAKKIVVLGDMLELGNQEVQFHYEVGKLIDPAKIAYVFTYGKLG 401
Cdd:PRK11929 827 MQRRRLSCGTRIIDDTYNANPDSMRAAIDVLAELPN-GPRALVLGDMLELGDNGPAMHREVGKYARQLGIDALITLGEAA 905
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1264383898 402 AQIAEgakiNFPIERVKAYDNKEELVKELQAVVDVKDVVLIKASRGMKLEEVITMLK 458
Cdd:PRK11929 906 RDAAA----AFGAGARGVCASVDEIIAALRGALPEGDSVLIKGSRFMRLERVVDALS 958
|
|
| murF |
PRK10773 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed |
1-458 |
2.62e-97 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed
Pssm-ID: 182718 [Multi-domain] Cd Length: 453 Bit Score: 299.64 E-value: 2.62e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 1 MINRTLKQVEQMVNGTGLAEQyegITIQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLWMKDVanpPEN 80
Cdd:PRK10773 1 MISVTLSQLADILNGELQGAD---ITIDAVTTDTRKVTPGCLFVALKGERFDAHDFADDAKAAGAGALLVSRPL---DID 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 81 LPVIFVEDTLSALQMLAKNYRNQLDVKVIGVTGSNGKTSTKDIVTSLLATKFKVQKTEGNFNNHIGLPLTILNLEENTEV 160
Cdd:PRK10773 75 LPQLVVKDTRLAFGQLAAWVRQQVPARVVALTGSSGKTSVKEMTAAILRQCGNTLYTAGNLNNDIGVPLTLLRLTPEHDY 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 161 AVLEMGMSSRGEIEFLSKLARPNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDepllTNRVP--KMN 238
Cdd:PRK10773 155 AVIELGANHQGEIAYTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNAD----SNDWLnwQSV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 239 LIAETV-TFGDARAN--DYYPTTVALQATGTHFKMNRDE-NISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVT 314
Cdd:PRK10773 231 IGSKTVwRFSPNAANsvDFTATNIHVTSHGTEFTLHTPTgSVDVLLPLPGRHNIANALAAAALAMSVGATLDAVKAGLAN 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 315 LQMTGMRMEIVKTDSGLTIINDAYNASPTAMEAAFHLMNGLDGFakKIVVLGDMLELGNQEVQFHYEVGKLIDPAKIAYV 394
Cdd:PRK10773 311 LKAVPGRLFPIQLAEGQLLLDDSYNANVGSMTAAAQVLAEMPGY--RVMVVGDMAELGAESEACHRQVGEAAKAAGIDKV 388
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1264383898 395 FTYGKLGAQIAEGAKinfpieRVKAYDNKEELVKELQAVVDVKDV--VLIKASRGMKLEEVITMLK 458
Cdd:PRK10773 389 LSVGKLSHAISEASG------VGEHFADKTALIARLKALLAEHQVitILVKGSRSAAMEEVVRALQ 448
|
|
| PRK14093 |
PRK14093 |
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; ... |
27-457 |
3.14e-79 |
|
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; Provisional
Pssm-ID: 184501 [Multi-domain] Cd Length: 479 Bit Score: 253.93 E-value: 3.14e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 27 IQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGA-VATLWMKDVANPPENLPVIFVEDTLSALQMLAKNYRNQLD 105
Cdd:PRK14093 28 VTGISIDSRTLAPGDAYFAIKGDVHDGHAFVAAALKAGAaLAVVERAQRDKFAADAPLLVVDDVLAALRDLGRAARARLE 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 106 VKVIGVTGSNGKTSTKDIVTSLLATKFKVQKTEGNFNNHIGLPLTILNLEENTEVAVLEMGMSSRGEIEFLSKLARPNAA 185
Cdd:PRK14093 108 AKVIAVTGSVGKTSTKEALRGVLGAQGETHASVASFNNHWGVPLSLARCPADARFAVFEIGMNHAGEIEPLVKMVRPHVA 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 186 IITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPL---LTNRVPKMNlIAETVTFGDARANDYYPTTVALQ 262
Cdd:PRK14093 188 IITTVEPVHLEFFSGIEAIADAKAEIFTGLEPGGAAVLNRDNPQfdrLAASARAAG-IARIVSFGADEKADARLLDVALH 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 263 ATGTHFKMN-RDENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMT---GMRMEIVKTDSGLTIINDAY 338
Cdd:PRK14093 267 ADCSAVHADiLGHDVTYKLGMPGRHIAMNSLAVLAAAELAGADLALAALALSQVQPAagrGVRHTLEVGGGEATLIDESY 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 339 NASPTAMEAAFHLMN--GLDGFAKKIVVLGDMLELGNQEVQFHYEVGKLIDPAKIAYVFTYGKLGAQIAEGakinFPIER 416
Cdd:PRK14093 347 NANPASMAAALGVLGraPVGPQGRRIAVLGDMLELGPRGPELHRGLAEAIRANAIDLVFCCGPLMRNLWDA----LSSGK 422
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1264383898 417 VKAY-DNKEELVKELQAVVDVKDVVLIKASRGMKLEEVITML 457
Cdd:PRK14093 423 RGGYaEDAAALESQVVAAIRAGDVIMVKGSLGSRMKTIVTAL 464
|
|
| PRK11930 |
PRK11930 |
putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine ... |
5-457 |
3.88e-77 |
|
putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional
Pssm-ID: 237026 [Multi-domain] Cd Length: 822 Bit Score: 256.81 E-value: 3.88e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 5 TLKQVEQMVNGTGLAEqyEGITIQGVSIDTRKIE--KGNLYVPIQGERFDGHAFVDKAVENGA----VATLWMKDVANPP 78
Cdd:PRK11930 4 TLESISGILGAEGLGD--KDAIIDQILTDSRSLSfpENTLFFALKGERNDGHRYIQELYEKGVrnfvVSEEKHPEESYPD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 79 ENLpvIFVEDTLSALQMLAKNYRNQLDVKVIGVTGSNGKTSTKDIVTSLLATKFKVQKTEGNFNNHIGLPLTILNLEENT 158
Cdd:PRK11930 82 ANF--LKVKDPLKALQELAAYHRSQFDIPVIGITGSNGKTIVKEWLYQLLSPDYNIVRSPRSYNSQIGVPLSVWQLNEEH 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 159 EVAVLEMGMSSRGEIEFLSKLARPNAAIITNIGEAHLMDLGSREAIAEAKLEIVTglqEGGVFVYNGDEPLLTNRVPKMN 238
Cdd:PRK11930 160 ELGIFEAGISQPGEMEALQKIIKPTIGILTNIGGAHQENFRSIKQKIMEKLKLFK---DCDVIIYNGDNELISSCITKSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 239 LIAETVTFGDARAN-DYYPTTVALQATGTHFKM-NRDENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQ 316
Cdd:PRK11930 237 LTLKLISWSRKDPEaPLYIPFVEKKEDHTVISYtYKGEDFHFEIPFIDDASIENLIHCIAVLLYLGYSADQIQERMARLE 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 317 MTGMRMEIVKTDSGLTIINDAYNASPTAMEAAFHLMNGLDGFAKKIVVLGDMLELGNQEVQFHYEVGKLIDPAKIAYVFT 396
Cdd:PRK11930 317 PVAMRLEVKEGINNCTLINDSYNSDLQSLDIALDFLNRRSQSKKKTLILSDILQSGQSPEELYRKVAQLISKRGIDRLIG 396
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1264383898 397 ygkLGAQIAEGAKInFPIERVKAYDNKEELVKELQAVVDVKDVVLIKASRGMKLEEVITML 457
Cdd:PRK11930 397 ---IGEEISSEASK-FEGTEKEFFKTTEAFLKSFAFLKFRNELILVKGARKFEFEQITELL 453
|
|
| MurE |
COG0769 |
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
29-366 |
2.12e-51 |
|
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440532 [Multi-domain] Cd Length: 459 Bit Score: 180.27 E-value: 2.12e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 29 GVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLWMKDVANPPENLPVIFVEDTLSALQMLAKNYRNQ--LDV 106
Cdd:COG0769 1 GITYDSRKVKPGDLFVALPGARVDGHDFIAQAIARGAVAVVTEAPGALLAAGVPVIVVPDPRAALALLAAAFYGHpsQKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 107 KVIGVTGSNGKTSTKDIVTSLL-ATKFKVqkteGNF---NNHIG-----LPLT---------ILN--LEENTEVAVLEmg 166
Cdd:COG0769 81 KLIGVTGTNGKTTTTYLLAQILrALGKKT----GLIgtvGNGIGgelipSSLTtpealdlqrLLAemVDAGVTHVVME-- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 167 MSSRG-------EIEFlsklarpNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEP----LLTnrvp 235
Cdd:COG0769 155 VSSHAldqgrvdGVRF-------DVAVFTNLTRDHLDYHGTMEAYFAAKARLFDQLGPGGAAVINADDPygrrLAA---- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 236 kmNLIAETVTFGDARANDYYPTTVALQATGTHFKMN-RDENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVT 314
Cdd:COG0769 224 --AAPARVITYGLKADADLRATDIELSADGTRFTLVtPGGEVEVRLPLIGRFNVYNALAAIAAALALGIDLEEILAALEK 301
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1264383898 315 LQM-TGmRMEIVKTDSGLTIINDaYNASPTAMEAAfhlMNGLDGFAKK--IVVLG 366
Cdd:COG0769 302 LKGvPG-RMERVDGGQGPTVIVD-YAHTPDALENV---LEALRPHTKGrlIVVFG 351
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
111-298 |
7.71e-51 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 170.95 E-value: 7.71e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 111 VTGSNGKTSTKDIVTSLLATKFKVQKTEG--------NFNNHIGLPLTILNL-EENTEVAVLEMGMSSRGEiEFLSKLAR 181
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGGVIGTIGtyigksgnTTNNAIGLPLTLAEMvEAGAEYAVLEVSSHGLGE-GRLSGLLK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 182 PNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNRVPKM-NLIAETVTFGDARANDYYPTTVA 260
Cdd:pfam08245 80 PDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPYGAFLIAKLkKAGVRVITYGIEGEADLRAANIE 159
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1264383898 261 LQATGTHFKMN--RDENISFYLPVLGKHNVYNTLASMAIA 298
Cdd:pfam08245 160 LSSDGTSFDLFtvPGGELEIEIPLLGRHNVYNALAAIAAA 199
|
|
| murE |
TIGR01085 |
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, ... |
24-349 |
5.61e-43 |
|
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase. An exception is Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is EC 6.3.2.7. The Mycobacteria, part of the closest neighboring branch outside of the low-GC Gram-positive bacteria, use diaminopimelate. A close homolog, scoring just below the trusted cutoff, is found (with introns) in Arabidopsis thaliana. Its role is unknown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273435 [Multi-domain] Cd Length: 464 Bit Score: 157.48 E-value: 5.61e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 24 GITIQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLWMKDVANPPENLPVIFVEDTLSALQMLAKNYRNQ 103
Cdd:TIGR01085 1 DLEVTGLTLDSREVKPGDLFVAIKGTHVDGHDFIHDAIANGAVAVVVERDVDFYVAPVPVIIVPDLRHALSSLAAAFYGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 104 L--DVKVIGVTGSNGKTSTkdivTSLLATKFKVQK-------TEGNF---NNHIGLP--------LTIL-----NLEENT 158
Cdd:TIGR01085 81 PskKLKVIGVTGTNGKTTT----TSLIAQLLRLLGkktgligTIGYRlggNDLIKNPaalttpeaLTLQstlaeMVEAGA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 159 EVAVLEmgMSSRG-------EIEFlsklarpNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPL-- 229
Cdd:TIGR01085 157 QYAVME--VSSHAlaqgrvrGVRF-------DAAVFTNLSRDHLDFHGTMENYFAAKASLFTELGLKRFAVINLDDEYga 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 230 -LTNRVPKMNLIAETVTFGDARANDYYPTTVALQATGTHFKM-NRDENISFYLPVLGKHNVYNTLASMAIAKHFG-VTWE 306
Cdd:TIGR01085 228 qFVKRLPKDITVSAITQPADGRAQDIKITDSGYSFEGQQFTFeTPAGEGHLHTPLIGRFNVYNLLAALATLLHLGgIDLE 307
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1264383898 307 EMKQGLVTLQMTGMRMEIVKTDSGLTIINDaYNASPTAMEAAF 349
Cdd:TIGR01085 308 DIVAALEKFRGVPGRMELVDGGQKFLVIVD-YAHTPDALEKAL 349
|
|
| MurD |
COG0771 |
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ... |
104-441 |
1.57e-37 |
|
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440534 [Multi-domain] Cd Length: 445 Bit Score: 142.14 E-value: 1.57e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 104 LDVKVIGVTGSNGKTSTkdivTSLLATKFKV--QKTE--GNfnnhIGLP-LTILNLEENTEVAVLEMgmSSRgEIEFLSK 178
Cdd:COG0771 103 SPAPIIAITGTNGKTTT----TTLIGHILKAagLRVAvgGN----IGTPlLDLLLEPEPPDVYVLEL--SSF-QLETTPS 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 179 LaRPNAAIITNIGEAHLmDL-GSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNRVPKMNliAETVTFG--DARANDYY 255
Cdd:COG0771 172 L-RPDVAVILNITPDHL-DRhGSMEAYAAAKARIFANQTPDDYAVLNADDPLTRALAEEAK--ARVVPFSlkEPLEGGAG 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 256 --PTTVALQATGtHFKMNRDEnisfyLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQmtGM--RMEIVKTDSGL 331
Cdd:COG0771 248 leDGKLVDRASG-EELLPVDD-----LRLPGRHNLENALAALAAARALGVPPEAIREALRSFK--GLphRLEFVAEINGV 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 332 TIIND--AYNasPTAMEAAfhlmngLDGFAKKIVVL-------GDMLELgnqeVQFHYEvgklidpaKIAYVFTYGKLGA 402
Cdd:COG0771 320 RFINDskATN--PDATLAA------LESFDGPVVLIaggldkgADFSPL----APAVAE--------RVKAVVLIGEDAE 379
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1264383898 403 QIAEGAK-INFPIERVkayDNKEELVKELQAVVDVKDVVL 441
Cdd:COG0771 380 KIAAALAgAGVPVVIV---ETMEEAVAAAAELARPGDVVL 416
|
|
| murD |
TIGR01087 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation ... |
105-441 |
1.99e-37 |
|
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273436 [Multi-domain] Cd Length: 433 Bit Score: 141.71 E-value: 1.99e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 105 DVKVIGVTGSNGKTSTKDIVTSLLATKFKVQKTEGNfnnhIGLPLTILNLEENTEVAVLEMgmsSRGEIEFLSKLaRPNA 184
Cdd:TIGR01087 101 PLPVVAITGTNGKTTTTSLLYHLLKAAGLKAFLGGN----IGTPALEVLDQEGAELYVLEL---SSFQLETTESL-RPEI 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 185 AIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNrvPKMNLIAETVTFGDARANDYYpttvALQAT 264
Cdd:TIGR01087 173 ALILNISEDHLDWHGSFEDYVAAKLKIFARQTEGDVAVLNADDPRFAR--LAQKSKAQVIWFSVEKDAERG----LCIRD 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 265 GTHFKMNRDENIsfylPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMTGMRMEIVKTDSGLTIINDAYNASPTA 344
Cdd:TIGR01087 247 GGLYLKPNDLEG----SLLGLHNAENILAAIALAKSLGLNLEAILEALRSFKGLPHRLEYVGQKNGVHFYNDSKATNVHA 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 345 MEAAfhlmngLDGFAKKIVVL--GDmlelgNQEVQFHYEVGKLIDPAKIAYVFtyGKLGAQIAEGAK-INFPIERVkayD 421
Cdd:TIGR01087 323 TLAA------LSAFDNPVILIvgGD-----DKGADFSPLAPAAAGKVKAVLAI--GEDAAKIAPLLKeAGLSVYLV---E 386
|
330 340
....*....|....*....|
gi 1264383898 422 NKEELVKELQAVVDVKDVVL 441
Cdd:TIGR01087 387 SLEEAVQAAREVASPGDVVL 406
|
|
| murE |
PRK00139 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional |
18-366 |
1.85e-36 |
|
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Pssm-ID: 234660 [Multi-domain] Cd Length: 460 Bit Score: 139.50 E-value: 1.85e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 18 LAEQYEGITIQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLWMKDVAnPPENLPVIFVEDTLSALQMLA 97
Cdd:PRK00139 6 LRDLLAPVEITGLTYDSRKVKPGDLFVALPGHKVDGRDFIAQAIANGAAAVVAEADGE-AGTGVPVIIVPDLRKALALLA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 98 KNY--RNQLDVKVIGVTGSNGKTSTKDIVTSLL-ATKFK--VQKTEGNF--NNHIGLPLT---ILNL--------EENTE 159
Cdd:PRK00139 85 AAFygHPSDKLKLIGVTGTNGKTTTAYLLAQILrLLGEKtaLIGTLGNGigGELIPSGLTtpdALDLqrllaelvDAGVT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 160 VAVLEmgMSSRG-------EIEFlsklarpNAAIITNIGEAHLmDL-GSREAIAEAKLEIVTGLqeGGVFVYNGDEPLlt 231
Cdd:PRK00139 165 YAAME--VSSHAldqgrvdGLKF-------DVAVFTNLSRDHL-DYhGTMEDYLAAKARLFSEL--GLAAVINADDEV-- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 232 nrvpKMNLIAETVTFGDARAN-DYYPTTVALQATGTHFKMNRDenisFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQ 310
Cdd:PRK00139 231 ----GRRLLALPDAYAVSMAGaDLRATDVEYTDSGQTFTLVTE----VESPLIGRFNVSNLLAALAALLALGVPLEDALA 302
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1264383898 311 GLVTLQMTGMRMEIVKTDSGLTIIND-AYNasPTAMEAAfhlMNGLDGFAKK--IVVLG 366
Cdd:PRK00139 303 ALAKLQGVPGRMERVDAGQGPLVIVDyAHT--PDALEKV---LEALRPHAKGrlICVFG 356
|
|
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
94-442 |
3.98e-30 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 121.71 E-value: 3.98e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 94 QMLAKNYRNQldvKVIGVTGSNGKTSTkdivTSLLATKFKvqktegnfnnHIGLPLTIL------NLEENtevAVLemgm 167
Cdd:COG0773 95 EMLAELMRGK---RSIAVAGTHGKTTT----TSMLAHILE----------EAGLDPTFLiggilnNFGTN---ARL---- 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 168 sSRGE---IE-------FLsKLaRPNAAIITNIgEA-HlMDL-GSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNRVP 235
Cdd:COG0773 151 -GDGDyfvAEadesdgsFL-HY-SPDIAVVTNI-EAdH-LDIyGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLP 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 236 KMNliAETVTFGDARANDYYPTTVALQATGTHFKMNRDENI--SFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLV 313
Cdd:COG0773 226 RCG--RPVITYGFSEDADYRAENIRIDGGGSTFDVLRRGEElgEVELNLPGRHNVLNALAAIAVALELGVDPEAIAEALA 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 314 TLQMTGMRMEIVKTDSGLTIINDaYNASPTAMEAAFHLMNGLDGFAKKIVVL--------GDMLElgnqevQFhyevGKL 385
Cdd:COG0773 304 SFKGVKRRFELKGEVGGVTVIDD-YAHHPTEIAATLAAAREKYPDRRLVAVFqphrysrtRDFLD------EF----AEA 372
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1264383898 386 IDPAKIAYVF---------TYGKLGAQIAEgaKINFPIERVKAYDNKEELVKELQAVVDVKDVVLI 442
Cdd:COG0773 373 LSLADEVILLdiyaarekpIPGVSSEDLAE--AIRKRGKDVVYVPDLDELVEALAEIARPGDVVLT 436
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
27-366 |
9.94e-29 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 119.81 E-value: 9.94e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 27 IQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLWMKDVANPPENLP--VIFVEDTLSALQMLAKNY--RN 102
Cdd:PRK11929 29 TADLRLDSREVQPGDLFVACRGAASDGRAFIDQALARGAAAVLVEAEGEDQVAAADalVLPVADLRKALGELAARWygRP 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 103 QLDVKVIGVTGSNGKTSTKDIVTSLLATKFKVQKTEGNFNNH-----IGLPLT---------ILN--LEENTEVAVLEmg 166
Cdd:PRK11929 109 SEQLSLVAVTGTNGKTSCAQLLAQLLTRLGKPCGSIGTLGARldgrlIPGSLTtpdaiilhrILArmRAAGADAVAME-- 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 167 MSSRG-EIEFLSKLaRPNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNRVPKMNLIAETVT 245
Cdd:PRK11929 187 ASSHGlEQGRLDGL-RIAVAGFTNLTRDHLDYHGTMQDYEEAKAALFSKLPGLGAAVINADDPAAARLLAALPRGLKVGY 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 246 FGDARANDYYPTTVALQATGTHFKM-NRDENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMTGMRMEI 324
Cdd:PRK11929 266 SPQNAGADVQARDLRATAHGQVFTLaTPDGSYQLVTRLLGRFNVSNLLLVAAALKKLGLPLAQIARALAAVSPVPGRMER 345
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1264383898 325 VK---TDSGLTIINDaYNASPTAMEAAFHLMNGLDGFAKK--IVVLG 366
Cdd:PRK11929 346 VGptaGAQGPLVVVD-YAHTPDALAKALTALRPVAQARNGrlVCVFG 391
|
|
| murD |
PRK14106 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional |
107-442 |
4.02e-20 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
Pssm-ID: 184511 [Multi-domain] Cd Length: 450 Bit Score: 92.34 E-value: 4.02e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 107 KVIGVTGSNGKTSTkdivTSLLATKFKVQ--KT--EGNfnnhIGLPL--TILNLEENTeVAVLEMgmsSRGEIEFLSKLa 180
Cdd:PRK14106 109 PIVAITGTNGKTTT----TTLLGEIFKNAgrKTlvAGN----IGYPLidAVEEYGEDD-IIVAEV---SSFQLETIKEF- 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 181 RPNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQEGGVFVYNGDEPL---LTNRVP-------KMNLIAETVTFGDAR 250
Cdd:PRK14106 176 KPKVGCILNITPDHLDRHKTMENYIKAKARIFENQRPSDYTVLNYDDPRtrsLAKKAKarviffsRKSLLEEGVFVKNGK 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 251 andyyptTVALQATGTHFKMNRDEnisfyLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMTGMRMEIVKTDSG 330
Cdd:PRK14106 256 -------IVISLGGKEEEVIDIDE-----IFIPGEHNLENALAATAAAYLLGISPDVIANTLKTFKGVEHRIEFVAEING 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 331 LTIINDAYNASPTAMEAAfhlmngLDGFAKKIVVLGDMLELGNqevQFHyEVGKLIDpAKIAYVFTYGKLGAQIAEGA-K 409
Cdd:PRK14106 324 VKFINDSKGTNPDAAIKA------LEAYETPIVLIAGGYDKGS---DFD-EFAKAFK-EKVKKLILLGETAQEIAEAArK 392
|
330 340 350
....*....|....*....|....*....|....
gi 1264383898 410 INFP-IERVKAYdnkEELVKELQAVVDVKDVVLI 442
Cdd:PRK14106 393 YGFDnILFAETL---EEAVKKAYEIAKPGDVVLL 423
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
26-101 |
1.60e-13 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 65.72 E-value: 1.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 26 TIQGVSIDTRKIEKGNLYVPIQGERFDGHAFVDKAVENGAVATLWMKDVAN--------PPENLPVIFVEDTLSALQMLA 97
Cdd:pfam01225 1 EIHFVGIDGRGMSPGALFLALKGYRVDGSDFIESLIALGAAAVVGHDAANNispdnpelEAAKVPGIPVIDRREALAELA 80
|
....
gi 1264383898 98 KNYR 101
Cdd:pfam01225 81 AAFY 84
|
|
| Mur_ligase_C |
pfam02875 |
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase ... |
318-396 |
1.56e-11 |
|
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460731 [Multi-domain] Cd Length: 87 Bit Score: 60.05 E-value: 1.56e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1264383898 318 TGMRMEIVKTDSGLTIINDaYNASPTAMEAAFHLMNGLDGFaKKIVVLGDMLELGNqevQFHYEVGKLIDPAKIAYVFT 396
Cdd:pfam02875 1 VPGRLEVVGENNGVLVIDD-YAHNPDAMEAALRALRNLFPG-RLILVFGGMGDRDA---EFHALLGRLAAALADVVILT 74
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
109-323 |
3.52e-10 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 62.14 E-value: 3.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 109 IGVTGSNGKTSTKDIVTSLLATkfkVQKTE----GNFNNhiglpLTILNLEENTEVAVLEMGmSSRGEIEFLSklarPNA 184
Cdd:PRK14573 107 ILVSGSHGKTTVSSLITAIFQE---AKKDPsyaiGGLNQ-----EGLNGYSGSSEYFVAEAD-ESDGSLKHYT----PEF 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 185 AIITNIGEAHLMDL-GSREAIAEAKLEIVTGLQEGGVFVYNGDEPLLTNRVpkmnliaETVTFGDARANDYYPTTVALQA 263
Cdd:PRK14573 174 SVITNIDNEHLSNFeGDRELLLASIQDFARKVQQINKCFYNGDCPRLKGCL-------QGHSYGFSSSCDLHILSYYQEG 246
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1264383898 264 TGTHFK---MNRD-ENISFYLPvlGKHNVYNTLASMAIAKHFGVTWEEMKQGLVTLQMTGMRME 323
Cdd:PRK14573 247 WRSYFSakfLGVVyQDIELNLV--GMHNVANAAAAMGIALTLGIDEGAIRNALKGFSGVQRRLE 308
|
|
| PRK14022 |
PRK14022 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase; |
22-447 |
1.52e-09 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase;
Pssm-ID: 237588 [Multi-domain] Cd Length: 481 Bit Score: 59.67 E-value: 1.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 22 YEGITIQGVSIDTRKIEKGNLYVpIQGERFDgHAFVDKAVENGavatLWMKDVANPPE-NLPVIFVEDTLSALQMLAKNY 100
Cdd:PRK14022 29 YSGVQFDDISYDSRTADEGTLFF-AKGAYFK-HKFLQNAITQG----LKLYVSEKDYEvGIPQVIVPDIKKAMSLIAMEF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 101 RN--QLDVKVIGVTGSNGKTS----TKDIV-----TSLLATKFKVQKTEGNFNNHIGLPLTiLNLEENTEVAV------L 163
Cdd:PRK14022 103 YDnpQHKLKLLAFTGTKGKTTaayfAYHILkqlhkPAMLSTMNTTLDGETFFKSALTTPES-LDLFKMMAEAVdngmthL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 164 EMGMSSRG-------EIEFlsklarpNAAIITNIGEAHL--MDLGSREAIAEAKLEIVTglQEGGVFVYNGDEplltnrv 234
Cdd:PRK14022 182 IMEVSSQAylvgrvyGLTF-------DVGVFLNITPDHIgpIEHPTFEDYFYHKRLLME--NSKAVVVNSDMD------- 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 235 pKMNLIAETVTFGDAranDYYPTTVALQATGTH---FKMNRDENISFYLPVLGKHNVYNTLASMAIAKHFGVTWEEMKQG 311
Cdd:PRK14022 246 -HFSELLEQVTPQEH---DFYGIDSENQIMASNafsFEATGKLAGTYDIQLIGKFNQENAMAAGLACLRLGASLEDIQKG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 312 LVTLQMTGmRMEIVKTDSGLTIINDaYNASPTAMEaafHLMNGLDGFAK-KIVVLGDMleLGNQEVQFHYEVGKLIDPA- 389
Cdd:PRK14022 322 IAQTPVPG-RMEVLTQSNGAKVFID-YAHNGDSLN---KLIDVVEEHQKgKLILLLGA--AGNKGESRRPDFGRVANRHp 394
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1264383898 390 KIAYVFTYG--------KLGAQIAEGakINFPIERVkayDNKEELVKELQAVVDVKDVVLIKASRG 447
Cdd:PRK14022 395 YLQVILTADdpnnedpkMITQEIASH--ITHPVEII---DDRAEAIKHAMSITEGPGDAVIIAGKG 455
|
|
| F430_CfbE |
NF033197 |
coenzyme F430 synthase; Members of this family are coenzyme F430 synthase, involving in ... |
77-337 |
3.80e-09 |
|
coenzyme F430 synthase; Members of this family are coenzyme F430 synthase, involving in synthesizing coenzyme F430, which is used in methanogens by coenzyme M reductase. Members of this family are restricted to archaeal methanogens, and resemble (and may be misannotated as) MurD, an enzyme of bacterial cell wall biosynthesis.
Pssm-ID: 467992 [Multi-domain] Cd Length: 419 Bit Score: 58.49 E-value: 3.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 77 PPENLPVIFVEDtlsALQMLAKNYRNQLDVKVIGVTGSNGKTSTKDIVTSLLATKFKVQKT--------EGNFNNHIGL- 147
Cdd:NF033197 66 PPDGKPFITHHE---AVGEILKKKYGRIPKKFIEITGVKGKTTTAELLAHILSDEYVLLHTsrgterypEGELSNKGSIt 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 148 PLTILNLEENTEvavlEMGMSSRGEIEF---LSKLARPNAAIITNIGEAHLMDLGSREAIAeAKLEIVTGLQEGGVFV-- 222
Cdd:NF033197 143 PASILNALELAE----EIGIDDYGFLIFevsLGGTGAGDVGIITNILEDYPIAGGKRSASA-AKLQSLKNAKVGSINVad 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264383898 223 ---YNGDEPLLTNRVPKmnliAETVTFGDARANDyypttvalqatgthfkmnRDENISFYLPVLGKHNVYNTLASMAIAK 299
Cdd:NF033197 218 lgiYINGKNKLVITVAG----VEILSKYPLRFKY------------------GNTEFEFNPLLFGPHYRENSLFAIEAAL 275
|
250 260 270
....*....|....*....|....*....|....*...
gi 1264383898 300 HFGVTWEEMKQGLVTLQMTGMRMEIVKTDsGLTIINDA 337
Cdd:NF033197 276 NLGVDPEDIISALKGFKGLPGRMAVKKEG-GVVIVDNI 312
|
|
| PLN02913 |
PLN02913 |
dihydrofolate synthetase |
155-212 |
4.52e-05 |
|
dihydrofolate synthetase
Pssm-ID: 178501 [Multi-domain] Cd Length: 510 Bit Score: 45.58 E-value: 4.52e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1264383898 155 EENTEVAVLEMGMS-SRGEIEFL--SKLArpnAAIITNIGEAHLMDL-GSREAIAEAKLEIV 212
Cdd:PLN02913 171 QENVDIAVIEAGLGgARDATNVIdsSGLA---ASVITTIGEEHLAALgGSLESIALAKSGII 229
|
|
| |
