|
Name |
Accession |
Description |
Interval |
E-value |
| NEAT |
COG5386 |
Heme-binding NEAT domain [Inorganic ion transport and metabolism]; |
7-248 |
2.30e-44 |
|
Heme-binding NEAT domain [Inorganic ion transport and metabolism];
Pssm-ID: 444149 [Multi-domain] Cd Length: 302 Bit Score: 162.38 E-value: 2.30e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 7 KRINAMIIAAALSLPFAVYSTPALAavaIEANKTGQGLEDGTYDAVIKAYKDKTNEESMAAVYIKDP-KLTIENGKKIVT 85
Cdd:COG5386 2 KKVFDGMLSVLLAALLSVTFASVDV---TEPTTAAATLADGTYSINFKVLKDGTDEASMMNQYFEKPaKLTVKNGKYYVT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 86 ATLSDSDFFQYLKTEDIhtpGVFHDVKVISEDKKKNgTKVIQFEVEELGKRYNMRMHIYIPTMAYDNKYQVQFEVNTLNL 165
Cdd:COG5386 79 MTLNDSSWVTSFKVEVN---GSFVDATVVSEDKAAN-TRVVEFEVPDLSKPLNAKVHVVIPAINYDHKYDVRLVFDTNSI 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 166 ENNVPEKQKENKEEQQ----------------------------------------------DENGNVILDKQLQKYINK 199
Cdd:COG5386 155 KPVGPVKEEPAPPPENttdpekledgtytidfkvlkdgtkeismmdqtrtvefknpkpsdnvTSTAANSGSLQAKEGIKS 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1267646580 200 YNLNRDNVDAPITKKDLLQIKTLSIY--SGKGINKITGLEYMTNLEKLTLR 248
Cdd:COG5386 235 QPTKSDSTSKPATTTKPKKKVVPIAVnsLKLGLKFSNTVNKKQILNKLTEG 285
|
|
| NEAT |
pfam05031 |
Iron Transport-associated domain; NEAT domains are heme and/or hemoprotein-binding modules ... |
44-161 |
3.09e-33 |
|
Iron Transport-associated domain; NEAT domains are heme and/or hemoprotein-binding modules highly conserved in secondary structure. They have roles in hemoprotein binding, heme extraction and heme transfer
Pssm-ID: 428269 [Multi-domain] Cd Length: 116 Bit Score: 123.91 E-value: 3.09e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 44 LEDGTYDAVIKAYKDKTNEESMAAVYIKDP-KLTIENGKKIVTATLSDSDFFQYLKTEdihTPGVFHDVKVISEDKKKNg 122
Cdd:pfam05031 2 LADGTYTIDFKVLKDGTDEASMANGYLDKPaKLTVKNGKKYVTLTLNNSDWIKNFKVE---VNGTLVDVEVVSEDTGKD- 77
|
90 100 110
....*....|....*....|....*....|....*....
gi 1267646580 123 TKVIQFEVEELGKRYNMRMHIYIPTMAYDNKYQVQFEVN 161
Cdd:pfam05031 78 TRTVRFEVPDLDKKLNAKVHVYVPMGNYDHKYDVQLQFD 116
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
158-554 |
1.21e-31 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 128.51 E-value: 1.21e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 158 FEVNTLNLENNVPEKQKENKEEQQDENGNVILDKQLQKYINKYNLNRDNVDAPITKKDLLQIKTLSIYSGKGINKITGLE 237
Cdd:COG4886 14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 238 YMTNLEKLTLRESNvkdisAISKLRGLKYVDLTSNSIESI-HPIEQLENINMLFLRDNKISDL-TPLSKMKKIKTLDLIG 315
Cdd:COG4886 94 DLTNLTELDLSGNE-----ELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSN 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 316 NNIKDI-QPLFTVSTMKQLYLANNQISDL-TGIDRLNNVELLWIGNNKINNV-ESISKMSNLIELEISDSEIKDISSLSQ 392
Cdd:COG4886 169 NQLTDLpEELGNLTNLKELDLSNNQITDLpEPLGNLTNLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGN 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 393 LGNLQVLNLEENYISDISPLSTLTNLHEINLGANEIFDVRPVEELGKRISIDIQRQKIFLNEGSVDEEIKIPVYNLKGEP 472
Cdd:COG4886 249 LTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLL 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 473 LQNINLQSEGATLNNGFIKWNSPGEKIYEFKLDTNSTESKIRFNGTVIQNIVEKQKESQNVILDKTLQQHINKENLGREN 552
Cdd:COG4886 329 LLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALL 408
|
..
gi 1267646580 553 LN 554
Cdd:COG4886 409 DA 410
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
283-437 |
5.66e-23 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 97.93 E-value: 5.66e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 283 LENINMLFLRDNKISDLTPLSKMKKIKTLDLIGNNIKDIQPLFTVSTMKQLYLANNQISDLTGIDRLNNVELLWIGNNKI 362
Cdd:cd21340 1 LKRITHLYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 363 NNVESISKMSNLIELEISD-------SEIKDISSLSQLGN-LQVLNLEENYISDISPLSTLTNLHEINLGANEIFDVRPV 434
Cdd:cd21340 81 SVVEGLENLTNLEELHIENqrlppgeKLTFDPRSLAALSNsLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEEL 160
|
...
gi 1267646580 435 EEL 437
Cdd:cd21340 161 LDL 163
|
|
| NEAT |
cd06920 |
NEAr Transport domain, a component of cell surface proteins; NEAr Transporter (NEAT) domain; ... |
46-165 |
9.83e-23 |
|
NEAr Transport domain, a component of cell surface proteins; NEAr Transporter (NEAT) domain; used by pathogenic bacteria to to scavenge heme-iron from host hemoproteins. The NEAT domain is a component of cell surface proteins (iron regulated surface determinants, or Isd, such as IsdA and IsdC) in various gram-positive bacteria, and may be arranged in tandem repeats.
Pssm-ID: 132993 [Multi-domain] Cd Length: 117 Bit Score: 93.91 E-value: 9.83e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 46 DGTYDAVIKAYKDKTNEESMAAVYIKDP-KLTIENGKKIVTATLSDSDFFQYLKTEDihtpGVFHDVKVISEDKKKNGTK 124
Cdd:cd06920 1 DGTYTVNFKVLKEGTDEPSMANGYLNKPaKLTVKNGKKYVTLTLKNSDWMKNFKVEV----NGGNKDVVVVKDDNSNNTR 76
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1267646580 125 VIQFEVEELGKRYNMRMHIYIPTMAYDNKYQVQFEVNTLNL 165
Cdd:cd06920 77 TVKFEVPDLDSKINAKVHVVVMGINYDHKYDVRLKFDTSSI 117
|
|
| NEAT |
smart00725 |
NEAr Transporter domain; |
45-162 |
6.33e-19 |
|
NEAr Transporter domain;
Pssm-ID: 214790 [Multi-domain] Cd Length: 123 Bit Score: 83.17 E-value: 6.33e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 45 EDGTYDAVIKAYKDKTNEESMAAVYIKDP-KLTIENGKKIVTATLSDSDFFQYLKTEdihTPGVFHDVKVISEDKKKNgT 123
Cdd:smart00725 1 ADGIYTINFVVLKDNSNEESMMDDYVNKPaKLIVKNGKTYVTLTLNNSSFWKDFEVE---VNGTKVDVEVVSKDKDND-T 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1267646580 124 KVIQFEVEELGKRYNMRMHIYIPTM---AYDNKYQVQFEVNT 162
Cdd:smart00725 77 RTIRFPVPNLDADLDAKVHVVVPEIgveNYDHDYTVQLIFDE 118
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
269-756 |
1.97e-14 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 76.51 E-value: 1.97e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 269 LTSNSIESIHPIEQLENINMLFLRDNKISDLTPLSKMKKIKTLDLIGNNIKDIQPLFTVSTMKQLYLANNQISDLTGIDR 348
Cdd:COG4886 10 LKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 349 LNNVELLWIGNNKINNVESISKMSNLIELEISDSEIKDI-SSLSQLGNLQVLNLEENYISDI-SPLSTLTNLHEINLGAN 426
Cdd:COG4886 90 TDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNN 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 427 EIFDVrpveelgkrisidiqrqkiflnegsvdeeikipvynlkgeplqninlqsegatlnngfikwnspgekiyefkldt 506
Cdd:COG4886 170 QLTDL--------------------------------------------------------------------------- 174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 507 nsteskirfngtviqnivekqkesqnvildktlqqhinkenlgrenlnapitKEDLLQIKKLEILKENGNEIKNI-TGLE 585
Cdd:COG4886 175 ----------------------------------------------------PEELGNLTNLKELDLSNNQITDLpEPLG 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 586 YMTNLEKLTLEGVGLKNI-EFISNLKQLNNVNVSHNQIEDITPLSSLENLQWLNLADNHIKDVTVIGSMLNLFSLNLAGN 664
Cdd:COG4886 203 NLTNLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNN 282
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 665 EIRD--VRPLIQLGQWFTIDVGRQNIILNDAKINEEIQVPVYDLEGESIENIQLTSEGGTFNNGVIKWNTPGEKVYKFDL 742
Cdd:COG4886 283 QLTDlkLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLL 362
|
490
....*....|....
gi 1267646580 743 DSDEISIRFNGTVI 756
Cdd:COG4886 363 LTLLLTLGLLGLLE 376
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
557-666 |
3.04e-14 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 72.90 E-value: 3.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 557 ITK-EDLLQIKKLEILKENGNEIKNITGLEYMTNLEKLTLEGVGLKN----------IEFISN-LKQLNnvnVSHNQIED 624
Cdd:cd21340 58 IEKiENLENLVNLKKLYLGGNRISVVEGLENLTNLEELHIENQRLPPgekltfdprsLAALSNsLRVLN---ISGNNIDS 134
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1267646580 625 ITPLSSLENLQWLNLADNHIKDVT----VIGSMLNLFSLNLAGNEI 666
Cdd:cd21340 135 LEPLAPLRNLEQLDASNNQISDLEelldLLSSWPSLRELDLTGNPV 180
|
|
| IsdC |
TIGR03656 |
heme uptake protein IsdC; Isd proteins are iron-regulated surface proteins found in Bacillus, ... |
20-212 |
3.44e-14 |
|
heme uptake protein IsdC; Isd proteins are iron-regulated surface proteins found in Bacillus, Staphylococcus and Listeria species and are responsible for heme scavenging from hemoproteins. The IsdC protein consists of an N-terminal hydrophobic signal sequence, a central NEAT (NEAr Transporter, pfam05031) domain, which confers the ability to bind heme, and a C-terminal SrtB processing signal which targets the protein to the cell wall. IsdC is believed to make a direct contact with, and transfer heme to, the heme-binding component (IsdE) of an ABC transporter in the cytoplasmic membrane, and to receive heme from other NEAT-containing heme-binding proteins also localized in the cell wall.
Pssm-ID: 274705 [Multi-domain] Cd Length: 217 Bit Score: 72.63 E-value: 3.44e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 20 LPFAVYSTPALAAVAIEANKTGQGLEDGTYDAVIKAYKDKTNEESMAAVYIKDP-KLTIENGKKIVTATLSDSDFFQYLK 98
Cdd:TIGR03656 5 LVFAFFTTILAFIILSAGFSNSANLADGTYTINYTVYKADNDSASMANDYFEKPaKLIVKNGKMTVQITVNHSHWITGFK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 99 TEDihtpgvfHDVKVISEDKKKNgTKVIQFEVEELGKRYNMRMHIYIPTMA-YDNKYQVQ--FEVNTLNLENNVPEKQKE 175
Cdd:TIGR03656 85 VEG-------NGVNVVSKNEAAD-KRTVEFPVSDLSGPIDGKIHVYVDDKVnYDHHYTIRlkFDGPTSVAGANAAGKDDK 156
|
170 180 190
....*....|....*....|....*....|....*..
gi 1267646580 176 NKEEQQDENGNVILDKQLQkyinKYNLNRDNVDAPIT 212
Cdd:TIGR03656 157 NSAEGSDKGSNGTTTKQSK----SESSNKDKVDNPQT 189
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
262-318 |
8.70e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.05 E-value: 8.70e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1267646580 262 RGLKYVDLTSNSIESIHP--IEQLENINMLFLRDNKISDLTP--LSKMKKIKTLDLIGNNI 318
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
588-644 |
4.95e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.74 E-value: 4.95e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1267646580 588 TNLEKLTLEGVGLKNI--EFISNLKQLNNVNVSHNQIEDITP--LSSLENLQWLNLADNHI 644
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
226-666 |
4.11e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 44.07 E-value: 4.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 226 SGKGINKITGLEYM--TNLEKLTLRESNVKDISAISKlrGLKYVDLTSNSIESIHPIEQLENINMLFLRDNKISDLTP-- 301
Cdd:PLN00113 82 SGKISSAIFRLPYIqtINLSNNQLSGPIPDDIFTTSS--SLRYLNLSNNNFTGSIPRGSIPNLETLDLSNNMLSGEIPnd 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 302 LSKMKKIKTLDLIGNNIKDIQPLF--TVSTMKQLYLANNQisdLTG-----IDRLNNVELLWIGNNKINN--VESISKMS 372
Cdd:PLN00113 160 IGSFSSLKVLDLGGNVLVGKIPNSltNLTSLEFLTLASNQ---LVGqipreLGQMKSLKWIYLGYNNLSGeiPYEIGGLT 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 373 NLIELE-ISDSEIKDI-SSLSQLGNLQVLNLEENYISDISPLS--TLTNLHEINLGANEIFDVRPveelgkRISIDIQRQ 448
Cdd:PLN00113 237 SLNHLDlVYNNLTGPIpSSLGNLKNLQYLFLYQNKLSGPIPPSifSLQKLISLDLSDNSLSGEIP------ELVIQLQNL 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 449 KIfLNEGSVDEEIKIPVYNLKGEPLQNINLQSEgaTLNNGFIKWNSPGEKIYEFKLDTNSTESKIR---------FNGTV 519
Cdd:PLN00113 311 EI-LHLFSNNFTGKIPVALTSLPRLQVLQLWSN--KFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPeglcssgnlFKLIL 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 520 IQNIVEKQKeSQNVILDKTLQQHINKENLGRENLNAPITKEDLLQIkkLEIlkENGNEIKNITGLEY-MTNLEKLTLEgv 598
Cdd:PLN00113 388 FSNSLEGEI-PKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYF--LDI--SNNNLQGRINSRKWdMPSLQMLSLA-- 460
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1267646580 599 glKNiEFISNL------KQLNNVNVSHNQIEDITP--LSSLENLQWLNLADNHIKDV--TVIGSMLNLFSLNLAGNEI 666
Cdd:PLN00113 461 --RN-KFFGGLpdsfgsKRLENLDLSRNQFSGAVPrkLGSLSELMQLKLSENKLSGEipDELSSCKKLVSLDLSHNQL 535
|
|
| LPXTG_anchor |
TIGR01167 |
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region ... |
825-856 |
1.05e-03 |
|
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other]
Pssm-ID: 273478 [Multi-domain] Cd Length: 34 Bit Score: 37.07 E-value: 1.05e-03
10 20 30
....*....|....*....|....*....|..
gi 1267646580 825 LPSTGGEASTSTLLSGITLVLSALSMFVFRKR 856
Cdd:TIGR01167 2 LPKTGESGNSLLLLLGLLLLGLGGLLLRKRKK 33
|
|
| Gram_pos_anchor |
pfam00746 |
LPXTG cell wall anchor motif; |
817-856 |
2.15e-03 |
|
LPXTG cell wall anchor motif;
Pssm-ID: 366278 [Multi-domain] Cd Length: 43 Bit Score: 36.75 E-value: 2.15e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1267646580 817 KPEEGKKFLPSTGGEASTSTLLSGITLVLSALSMFVFRKR 856
Cdd:pfam00746 1 AKKSKKKTLPKTGENSNIFLTAAGLLALLGGLLLLVKRRK 40
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NEAT |
COG5386 |
Heme-binding NEAT domain [Inorganic ion transport and metabolism]; |
7-248 |
2.30e-44 |
|
Heme-binding NEAT domain [Inorganic ion transport and metabolism];
Pssm-ID: 444149 [Multi-domain] Cd Length: 302 Bit Score: 162.38 E-value: 2.30e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 7 KRINAMIIAAALSLPFAVYSTPALAavaIEANKTGQGLEDGTYDAVIKAYKDKTNEESMAAVYIKDP-KLTIENGKKIVT 85
Cdd:COG5386 2 KKVFDGMLSVLLAALLSVTFASVDV---TEPTTAAATLADGTYSINFKVLKDGTDEASMMNQYFEKPaKLTVKNGKYYVT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 86 ATLSDSDFFQYLKTEDIhtpGVFHDVKVISEDKKKNgTKVIQFEVEELGKRYNMRMHIYIPTMAYDNKYQVQFEVNTLNL 165
Cdd:COG5386 79 MTLNDSSWVTSFKVEVN---GSFVDATVVSEDKAAN-TRVVEFEVPDLSKPLNAKVHVVIPAINYDHKYDVRLVFDTNSI 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 166 ENNVPEKQKENKEEQQ----------------------------------------------DENGNVILDKQLQKYINK 199
Cdd:COG5386 155 KPVGPVKEEPAPPPENttdpekledgtytidfkvlkdgtkeismmdqtrtvefknpkpsdnvTSTAANSGSLQAKEGIKS 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1267646580 200 YNLNRDNVDAPITKKDLLQIKTLSIY--SGKGINKITGLEYMTNLEKLTLR 248
Cdd:COG5386 235 QPTKSDSTSKPATTTKPKKKVVPIAVnsLKLGLKFSNTVNKKQILNKLTEG 285
|
|
| NEAT |
pfam05031 |
Iron Transport-associated domain; NEAT domains are heme and/or hemoprotein-binding modules ... |
44-161 |
3.09e-33 |
|
Iron Transport-associated domain; NEAT domains are heme and/or hemoprotein-binding modules highly conserved in secondary structure. They have roles in hemoprotein binding, heme extraction and heme transfer
Pssm-ID: 428269 [Multi-domain] Cd Length: 116 Bit Score: 123.91 E-value: 3.09e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 44 LEDGTYDAVIKAYKDKTNEESMAAVYIKDP-KLTIENGKKIVTATLSDSDFFQYLKTEdihTPGVFHDVKVISEDKKKNg 122
Cdd:pfam05031 2 LADGTYTIDFKVLKDGTDEASMANGYLDKPaKLTVKNGKKYVTLTLNNSDWIKNFKVE---VNGTLVDVEVVSEDTGKD- 77
|
90 100 110
....*....|....*....|....*....|....*....
gi 1267646580 123 TKVIQFEVEELGKRYNMRMHIYIPTMAYDNKYQVQFEVN 161
Cdd:pfam05031 78 TRTVRFEVPDLDKKLNAKVHVYVPMGNYDHKYDVQLQFD 116
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
158-554 |
1.21e-31 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 128.51 E-value: 1.21e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 158 FEVNTLNLENNVPEKQKENKEEQQDENGNVILDKQLQKYINKYNLNRDNVDAPITKKDLLQIKTLSIYSGKGINKITGLE 237
Cdd:COG4886 14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 238 YMTNLEKLTLRESNvkdisAISKLRGLKYVDLTSNSIESI-HPIEQLENINMLFLRDNKISDL-TPLSKMKKIKTLDLIG 315
Cdd:COG4886 94 DLTNLTELDLSGNE-----ELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSN 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 316 NNIKDI-QPLFTVSTMKQLYLANNQISDL-TGIDRLNNVELLWIGNNKINNV-ESISKMSNLIELEISDSEIKDISSLSQ 392
Cdd:COG4886 169 NQLTDLpEELGNLTNLKELDLSNNQITDLpEPLGNLTNLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGN 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 393 LGNLQVLNLEENYISDISPLSTLTNLHEINLGANEIFDVRPVEELGKRISIDIQRQKIFLNEGSVDEEIKIPVYNLKGEP 472
Cdd:COG4886 249 LTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLL 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 473 LQNINLQSEGATLNNGFIKWNSPGEKIYEFKLDTNSTESKIRFNGTVIQNIVEKQKESQNVILDKTLQQHINKENLGREN 552
Cdd:COG4886 329 LLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALL 408
|
..
gi 1267646580 553 LN 554
Cdd:COG4886 409 DA 410
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
283-437 |
5.66e-23 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 97.93 E-value: 5.66e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 283 LENINMLFLRDNKISDLTPLSKMKKIKTLDLIGNNIKDIQPLFTVSTMKQLYLANNQISDLTGIDRLNNVELLWIGNNKI 362
Cdd:cd21340 1 LKRITHLYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 363 NNVESISKMSNLIELEISD-------SEIKDISSLSQLGN-LQVLNLEENYISDISPLSTLTNLHEINLGANEIFDVRPV 434
Cdd:cd21340 81 SVVEGLENLTNLEELHIENqrlppgeKLTFDPRSLAALSNsLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEEL 160
|
...
gi 1267646580 435 EEL 437
Cdd:cd21340 161 LDL 163
|
|
| NEAT |
cd06920 |
NEAr Transport domain, a component of cell surface proteins; NEAr Transporter (NEAT) domain; ... |
46-165 |
9.83e-23 |
|
NEAr Transport domain, a component of cell surface proteins; NEAr Transporter (NEAT) domain; used by pathogenic bacteria to to scavenge heme-iron from host hemoproteins. The NEAT domain is a component of cell surface proteins (iron regulated surface determinants, or Isd, such as IsdA and IsdC) in various gram-positive bacteria, and may be arranged in tandem repeats.
Pssm-ID: 132993 [Multi-domain] Cd Length: 117 Bit Score: 93.91 E-value: 9.83e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 46 DGTYDAVIKAYKDKTNEESMAAVYIKDP-KLTIENGKKIVTATLSDSDFFQYLKTEDihtpGVFHDVKVISEDKKKNGTK 124
Cdd:cd06920 1 DGTYTVNFKVLKEGTDEPSMANGYLNKPaKLTVKNGKKYVTLTLKNSDWMKNFKVEV----NGGNKDVVVVKDDNSNNTR 76
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1267646580 125 VIQFEVEELGKRYNMRMHIYIPTMAYDNKYQVQFEVNTLNL 165
Cdd:cd06920 77 TVKFEVPDLDSKINAKVHVVVMGINYDHKYDVRLKFDTSSI 117
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
269-428 |
7.90e-21 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 91.77 E-value: 7.90e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 269 LTSNSIESIHPIEQLENINMLFLRDNKISDLTPLSKMKKIKTLDLIGNNIKDIQPLFTVSTMKQLYLANNQISDLTGIDR 348
Cdd:cd21340 9 LNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGLEN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 349 LNNVELLWIGNNKI----------NNVESISKmsNLIELEISDSEIKDISSLSQLGNLQVLNLEENYISDIS----PLST 414
Cdd:cd21340 89 LTNLEELHIENQRLppgekltfdpRSLAALSN--SLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEelldLLSS 166
|
170
....*....|....
gi 1267646580 415 LTNLHEINLGANEI 428
Cdd:cd21340 167 WPSLRELDLTGNPV 180
|
|
| NEAT |
smart00725 |
NEAr Transporter domain; |
45-162 |
6.33e-19 |
|
NEAr Transporter domain;
Pssm-ID: 214790 [Multi-domain] Cd Length: 123 Bit Score: 83.17 E-value: 6.33e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 45 EDGTYDAVIKAYKDKTNEESMAAVYIKDP-KLTIENGKKIVTATLSDSDFFQYLKTEdihTPGVFHDVKVISEDKKKNgT 123
Cdd:smart00725 1 ADGIYTINFVVLKDNSNEESMMDDYVNKPaKLIVKNGKTYVTLTLNNSSFWKDFEVE---VNGTKVDVEVVSKDKDND-T 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1267646580 124 KVIQFEVEELGKRYNMRMHIYIPTM---AYDNKYQVQFEVNT 162
Cdd:smart00725 77 RTIRFPVPNLDADLDAKVHVVVPEIgveNYDHDYTVQLIFDE 118
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
214-428 |
5.26e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 84.21 E-value: 5.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 214 KDLLQIKTLSIYSGKGINKITGLEYMTNLEKLTLRESNVKDISAISKLRGLKYVDLTSNSIESIHPIEQLENINMLFLRD 293
Cdd:COG4886 4 LLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 294 NKISDLTPLSKMKKIKTLDLIGNNikdiqPLFTVSTMKQLYLANNQISDL-TGIDRLNNVELLWIGNNKINNV-ESISKM 371
Cdd:COG4886 84 LLLLGLTDLGDLTNLTELDLSGNE-----ELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1267646580 372 SNLIELEISDSEIKDI-SSLSQLGNLQVLNLEENYISDIS-PLSTLTNLHEINLGANEI 428
Cdd:COG4886 159 TNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQL 217
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
269-756 |
1.97e-14 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 76.51 E-value: 1.97e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 269 LTSNSIESIHPIEQLENINMLFLRDNKISDLTPLSKMKKIKTLDLIGNNIKDIQPLFTVSTMKQLYLANNQISDLTGIDR 348
Cdd:COG4886 10 LKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 349 LNNVELLWIGNNKINNVESISKMSNLIELEISDSEIKDI-SSLSQLGNLQVLNLEENYISDI-SPLSTLTNLHEINLGAN 426
Cdd:COG4886 90 TDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNN 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 427 EIFDVrpveelgkrisidiqrqkiflnegsvdeeikipvynlkgeplqninlqsegatlnngfikwnspgekiyefkldt 506
Cdd:COG4886 170 QLTDL--------------------------------------------------------------------------- 174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 507 nsteskirfngtviqnivekqkesqnvildktlqqhinkenlgrenlnapitKEDLLQIKKLEILKENGNEIKNI-TGLE 585
Cdd:COG4886 175 ----------------------------------------------------PEELGNLTNLKELDLSNNQITDLpEPLG 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 586 YMTNLEKLTLEGVGLKNI-EFISNLKQLNNVNVSHNQIEDITPLSSLENLQWLNLADNHIKDVTVIGSMLNLFSLNLAGN 664
Cdd:COG4886 203 NLTNLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNN 282
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 665 EIRD--VRPLIQLGQWFTIDVGRQNIILNDAKINEEIQVPVYDLEGESIENIQLTSEGGTFNNGVIKWNTPGEKVYKFDL 742
Cdd:COG4886 283 QLTDlkLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLL 362
|
490
....*....|....
gi 1267646580 743 DSDEISIRFNGTVI 756
Cdd:COG4886 363 LTLLLTLGLLGLLE 376
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
557-666 |
3.04e-14 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 72.90 E-value: 3.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 557 ITK-EDLLQIKKLEILKENGNEIKNITGLEYMTNLEKLTLEGVGLKN----------IEFISN-LKQLNnvnVSHNQIED 624
Cdd:cd21340 58 IEKiENLENLVNLKKLYLGGNRISVVEGLENLTNLEELHIENQRLPPgekltfdprsLAALSNsLRVLN---ISGNNIDS 134
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1267646580 625 ITPLSSLENLQWLNLADNHIKDVT----VIGSMLNLFSLNLAGNEI 666
Cdd:cd21340 135 LEPLAPLRNLEQLDASNNQISDLEelldLLSSWPSLRELDLTGNPV 180
|
|
| IsdC |
TIGR03656 |
heme uptake protein IsdC; Isd proteins are iron-regulated surface proteins found in Bacillus, ... |
20-212 |
3.44e-14 |
|
heme uptake protein IsdC; Isd proteins are iron-regulated surface proteins found in Bacillus, Staphylococcus and Listeria species and are responsible for heme scavenging from hemoproteins. The IsdC protein consists of an N-terminal hydrophobic signal sequence, a central NEAT (NEAr Transporter, pfam05031) domain, which confers the ability to bind heme, and a C-terminal SrtB processing signal which targets the protein to the cell wall. IsdC is believed to make a direct contact with, and transfer heme to, the heme-binding component (IsdE) of an ABC transporter in the cytoplasmic membrane, and to receive heme from other NEAT-containing heme-binding proteins also localized in the cell wall.
Pssm-ID: 274705 [Multi-domain] Cd Length: 217 Bit Score: 72.63 E-value: 3.44e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 20 LPFAVYSTPALAAVAIEANKTGQGLEDGTYDAVIKAYKDKTNEESMAAVYIKDP-KLTIENGKKIVTATLSDSDFFQYLK 98
Cdd:TIGR03656 5 LVFAFFTTILAFIILSAGFSNSANLADGTYTINYTVYKADNDSASMANDYFEKPaKLIVKNGKMTVQITVNHSHWITGFK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 99 TEDihtpgvfHDVKVISEDKKKNgTKVIQFEVEELGKRYNMRMHIYIPTMA-YDNKYQVQ--FEVNTLNLENNVPEKQKE 175
Cdd:TIGR03656 85 VEG-------NGVNVVSKNEAAD-KRTVEFPVSDLSGPIDGKIHVYVDDKVnYDHHYTIRlkFDGPTSVAGANAAGKDDK 156
|
170 180 190
....*....|....*....|....*....|....*..
gi 1267646580 176 NKEEQQDENGNVILDKQLQkyinKYNLNRDNVDAPIT 212
Cdd:TIGR03656 157 NSAEGSDKGSNGTTTKQSK----SESSNKDKVDNPQT 189
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
493-669 |
2.95e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 59.95 E-value: 2.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 493 NSPGEKIYEFKLDTNSTESKIRFNGTVIQNIVEKQKESQNVILDKTLQQHINKENLGRENLNAPITKEDLLQIKKLEILK 572
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 573 ENGNEIKNITGLEYMTNLEKLTLEgvglkNIEFISNLKQLNNVNVSHNQIEDITP-LSSLENLQWLNLADNHIKDV-TVI 650
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLS-----GNEELSNLTNLESLDLSGNQLTDLPEeLANLTNLKELDLSNNQLTDLpEPL 155
|
170
....*....|....*....
gi 1267646580 651 GSMLNLFSLNLAGNEIRDV 669
Cdd:COG4886 156 GNLTNLKSLDLSNNQLTDL 174
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
267-463 |
4.40e-09 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 59.80 E-value: 4.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 267 VDLTSNSIESIHPI---EQLE---NINMLFLRDNKISDLTP------LSKMKKIKTLDLIGNNIKD------IQPLFTVS 328
Cdd:COG5238 185 VYLGCNQIGDEGIEelaEALTqntTVTTLWLKRNPIGDEGAeilaeaLKGNKSLTTLDLSNNQIGDegvialAEALKNNT 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 329 TMKQLYLANNQISDlTGIDRLN-------NVELLWIGNNKINN------VESISKMSNLIELEISDSEIKD------ISS 389
Cdd:COG5238 265 TVETLYLSGNQIGA-EGAIALAkalqgntTLTSLDLSVNRIGDegaialAEGLQGNKTLHTLNLAYNGIGAqgaialAKA 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 390 LSQLGNLQVLNLEENYISDISP------LSTLTNLHEINLGANEIFDvRPVEELGKRISID-IQRQKIFLNEGSVDEEIK 462
Cdd:COG5238 344 LQENTTLHSLDLSDNQIGDEGAialakyLEGNTTLRELNLGKNNIGK-QGAEALIDALQTNrLHTLILDGNLIGAEAQQR 422
|
.
gi 1267646580 463 I 463
Cdd:COG5238 423 L 423
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
231-423 |
1.95e-08 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 57.64 E-value: 1.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 231 NKIT----GLEYMTNLEKLTLRESNVKDISAISKLRGLKYVDLTSNSIESIHPIEQLENINMLFLRDNKISD--LTPLSK 304
Cdd:COG4886 215 NQLTdlpePLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDlkLKELEL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 305 MKKIKTLDLIGNNIKDIQPLFTVSTMKQLYLANNQISDLTGIDRLNNVELLWIGNNKINNVESISKMSNLIELEISDSEI 384
Cdd:COG4886 295 LLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGL 374
|
170 180 190
....*....|....*....|....*....|....*....
gi 1267646580 385 KDISSLSQLGNLQVLNLEENYISDISPLSTLTNLHEINL 423
Cdd:COG4886 375 LEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNT 413
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
230-316 |
5.08e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 54.41 E-value: 5.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 230 INKITGLEYMTNLE-------KLTLRESNVKD---ISAISKlrGLKYVDLTSNSIESIHPIEQLENINMLFLRDNKISDL 299
Cdd:cd21340 80 ISVVEGLENLTNLEelhienqRLPPGEKLTFDprsLAALSN--SLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDL 157
|
90 100
....*....|....*....|.
gi 1267646580 300 T----PLSKMKKIKTLDLIGN 316
Cdd:cd21340 158 EelldLLSSWPSLRELDLTGN 178
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
557-672 |
1.11e-06 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 50.55 E-value: 1.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 557 ITK-EDLLQIKKLEILKENGNEIKNITGLEYMTNLEKLTLEGVGLKNIEFISNLKQLNNVNVSHNQIEDITPLSSLENLQ 635
Cdd:cd21340 14 ITKiDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGLENLTNLE 93
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1267646580 636 WLNLADNH-------IKDVTVIGSMLN-LFSLNLAGNEIRDVRPL 672
Cdd:cd21340 94 ELHIENQRlppgeklTFDPRSLAALSNsLRVLNISGNNIDSLEPL 138
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
262-318 |
8.70e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.05 E-value: 8.70e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1267646580 262 RGLKYVDLTSNSIESIHP--IEQLENINMLFLRDNKISDLTP--LSKMKKIKTLDLIGNNI 318
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
240-296 |
1.35e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 43.28 E-value: 1.35e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1267646580 240 TNLEKLTLRESNVKDI--SAISKLRGLKYVDLTSNSIESIHP--IEQLENINMLFLRDNKI 296
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
588-644 |
4.95e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.74 E-value: 4.95e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1267646580 588 TNLEKLTLEGVGLKNI--EFISNLKQLNNVNVSHNQIEDITP--LSSLENLQWLNLADNHI 644
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
285-324 |
1.19e-04 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 40.31 E-value: 1.19e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1267646580 285 NINMLFLRDNKISDLTPLSKMKKIKTLDLIGNN-IKDIQPL 324
Cdd:pfam12799 2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNNkITDLSDL 42
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
255-428 |
1.20e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 45.04 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 255 ISAISKLRGLKYVDLTSNS--------IESIHPIEQLENinmLFLRDNKISD---------LTPLSKmkKIKTLDLIGNN 317
Cdd:cd00116 74 LQGLTKGCGLQELDLSDNAlgpdgcgvLESLLRSSSLQE---LKLNNNGLGDrglrllakgLKDLPP--ALEKLVLGRNR 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 318 I-----KDIQPLF-TVSTMKQLYLANNQISDlTGIDRL-------NNVELLWIGNNKINnvesiskmsnlieleisDSEI 384
Cdd:cd00116 149 LegascEALAKALrANRDLKELNLANNGIGD-AGIRALaeglkanCNLEVLDLNNNGLT-----------------DEGA 210
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1267646580 385 KDIS-SLSQLGNLQVLNLEENYISDI-------SPLSTLTNLHEINLGANEI 428
Cdd:cd00116 211 SALAeTLASLKSLEVLNLGDNNLTDAgaaalasALLSPNISLLTLSLSCNDI 262
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
593-667 |
3.15e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 42.85 E-value: 3.15e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1267646580 593 LTLEGvglKNIEFISNLKQLNNVNVSH---NQIEDITPLSSLENLQWLNLADNHIKDVTVIGSMLNLFSLNLAGNEIR 667
Cdd:cd21340 7 LYLND---KNITKIDNLSLCKNLKVLYlydNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRIS 81
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
226-666 |
4.11e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 44.07 E-value: 4.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 226 SGKGINKITGLEYM--TNLEKLTLRESNVKDISAISKlrGLKYVDLTSNSIESIHPIEQLENINMLFLRDNKISDLTP-- 301
Cdd:PLN00113 82 SGKISSAIFRLPYIqtINLSNNQLSGPIPDDIFTTSS--SLRYLNLSNNNFTGSIPRGSIPNLETLDLSNNMLSGEIPnd 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 302 LSKMKKIKTLDLIGNNIKDIQPLF--TVSTMKQLYLANNQisdLTG-----IDRLNNVELLWIGNNKINN--VESISKMS 372
Cdd:PLN00113 160 IGSFSSLKVLDLGGNVLVGKIPNSltNLTSLEFLTLASNQ---LVGqipreLGQMKSLKWIYLGYNNLSGeiPYEIGGLT 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 373 NLIELE-ISDSEIKDI-SSLSQLGNLQVLNLEENYISDISPLS--TLTNLHEINLGANEIFDVRPveelgkRISIDIQRQ 448
Cdd:PLN00113 237 SLNHLDlVYNNLTGPIpSSLGNLKNLQYLFLYQNKLSGPIPPSifSLQKLISLDLSDNSLSGEIP------ELVIQLQNL 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 449 KIfLNEGSVDEEIKIPVYNLKGEPLQNINLQSEgaTLNNGFIKWNSPGEKIYEFKLDTNSTESKIR---------FNGTV 519
Cdd:PLN00113 311 EI-LHLFSNNFTGKIPVALTSLPRLQVLQLWSN--KFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPeglcssgnlFKLIL 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 520 IQNIVEKQKeSQNVILDKTLQQHINKENLGRENLNAPITKEDLLQIkkLEIlkENGNEIKNITGLEY-MTNLEKLTLEgv 598
Cdd:PLN00113 388 FSNSLEGEI-PKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYF--LDI--SNNNLQGRINSRKWdMPSLQMLSLA-- 460
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1267646580 599 glKNiEFISNL------KQLNNVNVSHNQIEDITP--LSSLENLQWLNLADNHIKDV--TVIGSMLNLFSLNLAGNEI 666
Cdd:PLN00113 461 --RN-KFFGGLpdsfgsKRLENLDLSRNQFSGAVPrkLGSLSELMQLKLSENKLSGEipDELSSCKKLVSLDLSHNQL 535
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
611-666 |
4.26e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.04 E-value: 4.26e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 611 QLNNVNVSHNQIEDITP--LSSLENLQWLNLADNHIKDVT--VIGSMLNLFSLNLAGNEI 666
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSpgAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
565-644 |
5.51e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 42.08 E-value: 5.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 565 IKKLEILKENGNEIKNITGLEYMTNLEKLTLEGVGLKNIEFISNLKQLNNVNVSHNQIEDITPLSSLENLQWLNLADNHI 644
Cdd:cd21340 1 LKRITHLYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRI 80
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
395-426 |
7.01e-04 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 38.00 E-value: 7.01e-04
10 20 30
....*....|....*....|....*....|..
gi 1267646580 395 NLQVLNLEENYISDISPLSTLTNLHEINLGAN 426
Cdd:pfam12799 2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGN 33
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
372-428 |
8.65e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 38.27 E-value: 8.65e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1267646580 372 SNLIELEISDSEIKDI--SSLSQLGNLQVLNLEENYISDISP--LSTLTNLHEINLGANEI 428
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| LPXTG_anchor |
TIGR01167 |
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region ... |
825-856 |
1.05e-03 |
|
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other]
Pssm-ID: 273478 [Multi-domain] Cd Length: 34 Bit Score: 37.07 E-value: 1.05e-03
10 20 30
....*....|....*....|....*....|..
gi 1267646580 825 LPSTGGEASTSTLLSGITLVLSALSMFVFRKR 856
Cdd:TIGR01167 2 LPKTGESGNSLLLLLGLLLLGLGGLLLRKRKK 33
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
216-402 |
1.15e-03 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 42.23 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 216 LLQIKTLSIySGKGINKITGLEYMTNLEKLTLRESNVKDISAISKLRGLKYVDLTSNSIESIH--PIEQLENINMLFLRD 293
Cdd:COG4886 227 LTNLETLDL-SNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKlkELELLLGLNSLLLLL 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1267646580 294 NKISDLTPLSKMKKIKTLDLIGNNIKDIQPLFTVSTMKQLYLANNQISDLTGIDRLNNVELLWIGNNKINNVESISKMSN 373
Cdd:COG4886 306 LLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALL 385
|
170 180
....*....|....*....|....*....
gi 1267646580 374 LIELEISDSEIKDISSLSQLGNLQVLNLE 402
Cdd:COG4886 386 LLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
373-413 |
1.24e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 37.22 E-value: 1.24e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1267646580 373 NLIELEISDSEIKDISSLSQLGNLQVLNLEEN-YISDISPLS 413
Cdd:pfam12799 2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDLA 43
|
|
| Gram_pos_anchor |
pfam00746 |
LPXTG cell wall anchor motif; |
817-856 |
2.15e-03 |
|
LPXTG cell wall anchor motif;
Pssm-ID: 366278 [Multi-domain] Cd Length: 43 Bit Score: 36.75 E-value: 2.15e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1267646580 817 KPEEGKKFLPSTGGEASTSTLLSGITLVLSALSMFVFRKR 856
Cdd:pfam00746 1 AKKSKKKTLPKTGENSNIFLTAAGLLALLGGLLLLVKRRK 40
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
588-630 |
6.31e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 35.30 E-value: 6.31e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1267646580 588 TNLEKLTLEGVGLKNIEFISNLKQLNNVNVSHN-QIEDITPLSS 630
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDLAN 44
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
633-672 |
8.16e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 34.91 E-value: 8.16e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1267646580 633 NLQWLNLADNHIKDVTVIGSMLNLFSLNLAGN-EIRDVRPL 672
Cdd:pfam12799 2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDL 42
|
|
| |
