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Conserved domains on  [gi|1268149752|ref|WP_098703129.1|]
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MIP/aquaporin family protein

Protein Classification

MIP/aquaporin family protein( domain architecture ID 10001739)

MIP (Major Intrinsic Protein)/aquaporin family protein similar to aquaporin that permits osmotically driven movement of water in both directions, and glycerol uptake facilitator protein that mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism

CATH:  1.20.1080.10
Gene Ontology:  GO:0055085|GO:0015267
SCOP:  3000508
TCDB:  1.A.8

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
37-240 2.14e-71

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


:

Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 217.69  E-value: 2.14e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  37 GAGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKAQMDEEPE 116
Cdd:COG0580    33 GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPWKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATED 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 117 AGVKLGVFSTGPSIDA-PIWNIVTEVIATALLLIGVLAIGYGEVGiQAGNGAFFVGLLIVVLGMATGGATGYALNPARDL 195
Cdd:COG0580   113 GGAKLGVFATSPAIGYsLGAAFLTEIIGTFVLVFVILGITDKRAA-PGGLAPLAIGLLVAAIGLSLGPLTGYAINPARDL 191
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1268149752 196 GPRIAHAIlpikGKGGSNWKYSWIPVVGPIIGAVLGAVIFDAFIA 240
Cdd:COG0580   192 GPRLFHAL----GKGGSDWGYLWVPIVAPILGAALAALLYRALFG 232
 
Name Accession Description Interval E-value
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
37-240 2.14e-71

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 217.69  E-value: 2.14e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  37 GAGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKAQMDEEPE 116
Cdd:COG0580    33 GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPWKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATED 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 117 AGVKLGVFSTGPSIDA-PIWNIVTEVIATALLLIGVLAIGYGEVGiQAGNGAFFVGLLIVVLGMATGGATGYALNPARDL 195
Cdd:COG0580   113 GGAKLGVFATSPAIGYsLGAAFLTEIIGTFVLVFVILGITDKRAA-PGGLAPLAIGLLVAAIGLSLGPLTGYAINPARDL 191
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1268149752 196 GPRIAHAIlpikGKGGSNWKYSWIPVVGPIIGAVLGAVIFDAFIA 240
Cdd:COG0580   192 GPRLFHAL----GKGGSDWGYLWVPIVAPILGAALAALLYRALFG 232
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
32-243 3.76e-45

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 152.59  E-value: 3.76e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  32 HSYGKGAGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKAQM 111
Cdd:PTZ00016   75 HTVGNNGDYLAITIGWGLGVTFGLLVSAGISGGHLNPAVTLGNAVFGKFPWKKLPGYFVAQLLGAFVGAACVYGLYYGFF 154
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 112 DE--------EPEAGVKLGVFSTGPSIDAPiWNIVTEVIATALLLIGVLAIGYGEVGIQAGNGAFFVGLLIVVLGMATGG 183
Cdd:PTZ00016  155 KDhgipelpwETMANGFAGVFATYPREGNF-YAIFSELILTAILLLVILAITDPNNCPAFNYLPVAVGLLVFVIGISFGG 233
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 184 ATGYALNPARDLGPRIAHAILPIKGKGGSNWKYSWIPVVGPIIGAVLGAVIFDAFIAAVI 243
Cdd:PTZ00016  234 NTGYALNPARDLGPRLFSAILWGSEVFTKDNYYFWVPLVAPFVGAVLGMFLYDKFIPPLI 293
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
28-238 1.05e-39

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 136.61  E-value: 1.05e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  28 CSLKHSYGKGAGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTY 107
Cdd:cd00333    22 LAVKLAGGASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIRVIPYIIAQLLGAILGAALLYGLY 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 108 KAQMDE-EPEAGVKLGVFSTGPSIDAPIWN-IVTEVIATALLLIGVLAI---GYGevGIQAGNGAFFVGLLIVVLGMATG 182
Cdd:cd00333   102 YGLYLEfLGANNIVAGIFGTYPSPGVSNGNaFFVEFIGTFILVLVVFATtddPNG--PPPGGLAPLAIGLLVAAIGLAGG 179
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1268149752 183 GATGYALNPARDLGPRIAHAILpikgkggSNWKYSWIPVVGPIIGAVLGAVIFDAF 238
Cdd:cd00333   180 PITGASMNPARSLGPALFTGLA-------RHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
37-235 8.95e-36

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 126.26  E-value: 8.95e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  37 GAGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKaqmdeePE 116
Cdd:TIGR00861  31 GGQFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRVPVYIVAQLIGAILGAALLYGLTS------GL 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 117 AGVKLGVFSTGPSIDAPIWNIVTEVIATALLLIGVLAIG-YGEVGIQAGNGAFFVGLLIVVLGMATGGATGYALNPARDL 195
Cdd:TIGR00861 105 FPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTdDRNRVPRGGFAPLAIGLLVFLIHLSMGPYTGTGMNPARSL 184
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1268149752 196 GPRIAHailpikgkGGSNWKYSWIPVVGPIIGAVLGAVIF 235
Cdd:TIGR00861 185 GPALFA--------GLAGWGNHWVYWVGPIIGAILGALVY 216
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
38-235 4.44e-25

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 98.54  E-value: 4.44e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  38 AGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKaqmdeepeA 117
Cdd:pfam00230  42 SGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLVGRRFSLLRAIFYIVAQLLGAIAGAALLYGVTV--------G 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 118 GVKLGVFSTGPSIDAPIWN-IVTEVIATALLLIGVLAIGYGEVGIQAGNGA-FFVGLLIVVLGMATGGATGYALNPARDL 195
Cdd:pfam00230 114 LQRAGLFANTLAPGVNAGQaFVVEIILTFQLVYCVFATTDDRRNGSLGTVApLAIGFAVFLNHLAGGPYTGASMNPARSF 193
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1268149752 196 GPRIAHailpikgkggSNWKYSWIPVVGPIIGAVLGAVIF 235
Cdd:pfam00230 194 GPAVVL----------WKWDDHWVYWVGPFIGAALGALVY 223
 
Name Accession Description Interval E-value
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
37-240 2.14e-71

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 217.69  E-value: 2.14e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  37 GAGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKAQMDEEPE 116
Cdd:COG0580    33 GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPWKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATED 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 117 AGVKLGVFSTGPSIDA-PIWNIVTEVIATALLLIGVLAIGYGEVGiQAGNGAFFVGLLIVVLGMATGGATGYALNPARDL 195
Cdd:COG0580   113 GGAKLGVFATSPAIGYsLGAAFLTEIIGTFVLVFVILGITDKRAA-PGGLAPLAIGLLVAAIGLSLGPLTGYAINPARDL 191
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1268149752 196 GPRIAHAIlpikGKGGSNWKYSWIPVVGPIIGAVLGAVIFDAFIA 240
Cdd:COG0580   192 GPRLFHAL----GKGGSDWGYLWVPIVAPILGAALAALLYRALFG 232
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
32-243 3.76e-45

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 152.59  E-value: 3.76e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  32 HSYGKGAGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKAQM 111
Cdd:PTZ00016   75 HTVGNNGDYLAITIGWGLGVTFGLLVSAGISGGHLNPAVTLGNAVFGKFPWKKLPGYFVAQLLGAFVGAACVYGLYYGFF 154
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 112 DE--------EPEAGVKLGVFSTGPSIDAPiWNIVTEVIATALLLIGVLAIGYGEVGIQAGNGAFFVGLLIVVLGMATGG 183
Cdd:PTZ00016  155 KDhgipelpwETMANGFAGVFATYPREGNF-YAIFSELILTAILLLVILAITDPNNCPAFNYLPVAVGLLVFVIGISFGG 233
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 184 ATGYALNPARDLGPRIAHAILPIKGKGGSNWKYSWIPVVGPIIGAVLGAVIFDAFIAAVI 243
Cdd:PTZ00016  234 NTGYALNPARDLGPRLFSAILWGSEVFTKDNYYFWVPLVAPFVGAVLGMFLYDKFIPPLI 293
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
28-238 1.05e-39

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 136.61  E-value: 1.05e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  28 CSLKHSYGKGAGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTY 107
Cdd:cd00333    22 LAVKLAGGASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIRVIPYIIAQLLGAILGAALLYGLY 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 108 KAQMDE-EPEAGVKLGVFSTGPSIDAPIWN-IVTEVIATALLLIGVLAI---GYGevGIQAGNGAFFVGLLIVVLGMATG 182
Cdd:cd00333   102 YGLYLEfLGANNIVAGIFGTYPSPGVSNGNaFFVEFIGTFILVLVVFATtddPNG--PPPGGLAPLAIGLLVAAIGLAGG 179
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1268149752 183 GATGYALNPARDLGPRIAHAILpikgkggSNWKYSWIPVVGPIIGAVLGAVIFDAF 238
Cdd:cd00333   180 PITGASMNPARSLGPALFTGLA-------RHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
37-235 8.95e-36

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 126.26  E-value: 8.95e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  37 GAGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKaqmdeePE 116
Cdd:TIGR00861  31 GGQFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRVPVYIVAQLIGAILGAALLYGLTS------GL 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 117 AGVKLGVFSTGPSIDAPIWNIVTEVIATALLLIGVLAIG-YGEVGIQAGNGAFFVGLLIVVLGMATGGATGYALNPARDL 195
Cdd:TIGR00861 105 FPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTdDRNRVPRGGFAPLAIGLLVFLIHLSMGPYTGTGMNPARSL 184
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1268149752 196 GPRIAHailpikgkGGSNWKYSWIPVVGPIIGAVLGAVIF 235
Cdd:TIGR00861 185 GPALFA--------GLAGWGNHWVYWVGPIIGAILGALVY 216
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
38-235 4.44e-25

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 98.54  E-value: 4.44e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  38 AGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKaqmdeepeA 117
Cdd:pfam00230  42 SGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLVGRRFSLLRAIFYIVAQLLGAIAGAALLYGVTV--------G 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 118 GVKLGVFSTGPSIDAPIWN-IVTEVIATALLLIGVLAIGYGEVGIQAGNGA-FFVGLLIVVLGMATGGATGYALNPARDL 195
Cdd:pfam00230 114 LQRAGLFANTLAPGVNAGQaFVVEIILTFQLVYCVFATTDDRRNGSLGTVApLAIGFAVFLNHLAGGPYTGASMNPARSF 193
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1268149752 196 GPRIAHailpikgkggSNWKYSWIPVVGPIIGAVLGAVIF 235
Cdd:pfam00230 194 GPAVVL----------WKWDDHWVYWVGPFIGAALGALVY 223
PLN00182 PLN00182
putative aquaporin NIP4; Provisional
47-236 2.92e-21

putative aquaporin NIP4; Provisional


Pssm-ID: 165748  Cd Length: 283  Bit Score: 89.58  E-value: 2.92e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  47 WGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIagatLAYLTYKAQMDEEPEAgvklgVFST 126
Cdd:PLN00182   82 WGLIVMVMIYSTGHISGAHFNPAVTVTFAIFRRFPWYQVPLYIGAQLTGSL----LASLTLRLMFNVTPEA-----FFGT 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 127 GPsIDAPIWNIVTEVIATALLL--IGVLAIGYGEVGIQAGngaFFVGLLIVVLGMATGGATGYALNPARDLGPRIahail 204
Cdd:PLN00182  153 TP-TDSSGQALVAEIIISFLLMfvISGVATDSRAVGELAG---IAVGMTIILNVFVAGPISGASMNPARSLGPAI----- 223
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1268149752 205 pIKGKggsnWKYSWIPVVGPIIGAVLGAVIFD 236
Cdd:PLN00182  224 -VMGR----YKGIWVYIVGPFVGIIAGGFVYN 250
PLN00183 PLN00183
putative aquaporin NIP7; Provisional
48-235 8.42e-19

putative aquaporin NIP7; Provisional


Pssm-ID: 215092  Cd Length: 274  Bit Score: 82.98  E-value: 8.42e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  48 GFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYkaqmdeepeaGVKLGVFSTG 127
Cdd:PLN00183   86 GLTVVVVVFSIGSISGAHVNPSVTIAFATFGHFPWSKVPLYITAQTVGSVLATYVGVSVY----------GVKADLMTTK 155
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 128 PSI--DAPIWnivTEVIATALLLIGVLAIGYGEVGIQAGNGaFFVGLLIVVLGMATGGATGYALNPARDLGPRIAhailp 205
Cdd:PLN00183  156 PAQgcSSAFW---VEFIATFIVMFLAASLTSQPQSLGHLSG-FVIGIAIGLAVLITGPVSGGSMNPARSLGPAIV----- 226
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1268149752 206 ikgkggsNWKYS--WIPVVGPIIGAVLGAVIF 235
Cdd:PLN00183  227 -------SWDFKdiWIYITAPTIGAVAGALMF 251
PLN00184 PLN00184
aquaporin NIP1; Provisional
47-236 5.53e-18

aquaporin NIP1; Provisional


Pssm-ID: 177778  Cd Length: 296  Bit Score: 80.84  E-value: 5.53e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  47 WGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGG-IAGATLAYLTykaQMDEEPEAGvKLGVFS 125
Cdd:PLN00184   94 WGLTIMVLIYSLGHISGAHINPAVTIAFASCGRFPLKQVPAYVISQVIGStLAAATLRLLF---GLDHDVCSG-KHDVFI 169
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 126 TGPSIDAPIWNIVTEVIATALLL--IGVLAIGYGEVGIQAGngaFFVGLLIVVLGMATGGATGYALNPARDLGPRIAHai 203
Cdd:PLN00184  170 GSSPVGSDLQAFVMEFIVTFYLMfiISGVATDNRAIGELAG---LAIGSTVLLNVLIAAPVSSASMNPGRSLGPAMVY-- 244
                         170       180       190
                  ....*....|....*....|....*....|...
gi 1268149752 204 lpikgkggSNWKYSWIPVVGPIIGAVLGAVIFD 236
Cdd:PLN00184  245 --------GCYKGIWIYIVAPTLGAIAGAWVYN 269
PLN00026 PLN00026
aquaporin NIP; Provisional
48-237 1.73e-16

aquaporin NIP; Provisional


Pssm-ID: 177663 [Multi-domain]  Cd Length: 298  Bit Score: 76.82  E-value: 1.73e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  48 GFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGAtlayLTYKAQMDEEPEAGVKLGVFSTG 127
Cdd:PLN00026  112 GLAVMIVILSTGHISGAHLNPSLTIAFAALRHFPWKHVPAYIAAQVSASICAS----FALKGVFHPFMSGGVTVPSVSTG 187
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 128 PSidapiwnIVTEVIATALLLIGVLAIGYG--EVGIQAGngaFFVGLLIVVLGMATGGATGYALNPARDLGPRIAhailp 205
Cdd:PLN00026  188 QA-------FALEFIITFNLLFVVTAVATDtrAVGELAG---IAVGATVMLNILVAGPSTGGSMNPVRTLGPAVA----- 252
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1268149752 206 ikgkgGSNWKYSWIPVVGPIIGAVLGAVIFDA 237
Cdd:PLN00026  253 -----AGNYRAIWIYLVAPTLGALAGAGTYTA 279
PRK05420 PRK05420
aquaporin Z; Provisional
37-238 3.79e-16

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 74.62  E-value: 3.79e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  37 GAGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKAQMDEEpe 116
Cdd:PRK05420   33 GIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKELVPYIIAQVVGGIAAAAVLYLIASGKAGFD-- 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 117 aGVKLGVFSTGPSIDAP-----IWNIVTEVIATALLLIGVLaiGYGEVGIQAGNGAFFVGLLIVVLGMATGGATGYALNP 191
Cdd:PRK05420  111 -LAGSGFASNGYGEHSPggyslLAALVCEVVLTAFFLLVIL--GATDKRAPAGFAPIAIGLALTLIHLISIPVTNTSVNP 187
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1268149752 192 ARDLGPRIAhailpikgKGGSNWKYSWIPVVGPIIGAVLGAVIFDAF 238
Cdd:PRK05420  188 ARSTGVALF--------VGGWALEQLWLFWVAPIVGAIIGGLIYRLL 226
PLN00166 PLN00166
aquaporin TIP2; Provisional
38-241 1.14e-09

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 56.87  E-value: 1.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  38 AGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLayLTYKAQMDEEPEA 117
Cdd:PLN00166   54 AGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTLGLAIGGNITIITGFFYWIAQCLGSIVACLL--LVFVTNGESVPTH 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 118 GVKLGVfstgpsidAPIWNIVTEVIATALLLIGVLAIGY----GEVGIQAgngAFFVGLLIVVLGMATGGATGYALNPAR 193
Cdd:PLN00166  132 GVAAGL--------GAIEGVVMEIVVTFALVYTVYATAAdpkkGSLGTIA---PIAIGFIVGANILAAGPFSGGSMNPAR 200
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1268149752 194 DLGPRIahailpIKGKGGSNWKYsWipvVGPIIGAVLGAVIF-DAFIAA 241
Cdd:PLN00166  201 SFGPAV------VSGDFSQIWIY-W---VGPLVGGALAGLIYgDVFIGS 239
PLN00027 PLN00027
aquaporin TIP; Provisional
38-238 8.14e-07

aquaporin TIP; Provisional


Pssm-ID: 177664  Cd Length: 252  Bit Score: 48.63  E-value: 8.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  38 AGWIVTTFGWGFAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTykaqmdeepEA 117
Cdd:PLN00027   56 AGLVAAALAHAFALFVAVSVGANISGGHVNPAVTFGAFIGGNITLLRGILYWIAQLLGSVVACLLLKFS---------TG 126
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 118 GVKLGVFSTGPSIDApiWN-IVTEVIATALLLIGVLAIGY----GEVGIQAgngAFFVGLLIVVLGMATGGATGYALNPA 192
Cdd:PLN00027  127 GLETSAFSLSSGVGV--WNaFVFEIVMTFGLVYTVYATAVdpkkGDLGIIA---PIAIGFIVGANILAGGAFDGASMNPA 201
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1268149752 193 RDLGPRIAhailpikgkgGSNWKYSWIPVVGPIIGAVLGAVIFDAF 238
Cdd:PLN00027  202 VSFGPAVV----------SWTWTNHWVYWAGPLIGGGIAGLVYELI 237
PLN00167 PLN00167
aquaporin TIP5; Provisional
49-236 4.22e-05

aquaporin TIP5; Provisional


Pssm-ID: 215085  Cd Length: 256  Bit Score: 43.74  E-value: 4.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752  49 FAVMIPAYVTGWVSGAHMNPALTIALAVTGKFPGELVFGYIIAQMLGGIAGATLAYLTYKAQmdEEPEAGVKLGVFSTGP 128
Cdd:PLN00167   69 FALSSAVYIAANISGGHVNPAVTFGMAVGGHISVPTAMFYWISQMLASVMACLFLKVTTVGQ--HVPTYKIAEEMTGFGA 146
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1268149752 129 SidapiwniVTEVIATALLLIGVLAIGYGEVGIQAGNGAFFVGLLIVVLGMATGGATGYALNPARDLGPRIAhailpikg 208
Cdd:PLN00167  147 S--------VLEGVLTFGLVYTVYAAGDPRRGLLGAIGPLAIGLVAGANVLAAGPFSGGSMNPACAFGSAVV-------- 210
                         170       180
                  ....*....|....*....|....*...
gi 1268149752 209 kgGSNWKYSWIPVVGPIIGAVLGAVIFD 236
Cdd:PLN00167  211 --AGSFKNQAVYWVGPLLGGAVAGLLYD 236
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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