|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
22-428 |
3.53e-129 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 380.37 E-value: 3.53e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 22 TNRLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQ 101
Cdd:cd13136 1 LHREILALALPAILSNITVPLLGLVDTAVVGHLGSAAYLGAVALGTTIFNTLFWLFGFLRMGTTGLVAQALGAGDREEAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 102 AVFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQT 181
Cdd:cd13136 81 ALLVRALLLALAIGLLLILLQSPLLALALLLLGASAAVAALARQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLILQI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 182 LINGTNIVLSILLGLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNRDIMIRSFA 261
Cdd:cd13136 161 VGNVVNIVLDPLFVFGLGWGVAGAALATVIAQYLGALLGLWLLRRRVRLLGKSLSRRLPSKAALKRLFKLNRDIFIRTLA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 262 LLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLGLAASTTL 341
Cdd:cd13136 241 LLAAFLFFTALAARLGDVILAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLQWGLGLGVLLAL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 342 VLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGWSRDMRNMMLAAFIGYVAALAVLVPAFGN 421
Cdd:cd13136 321 LFFLGGEPIIRLFTDDPAVLALAATYLPWLALLPPIGALAFVLDGIFIGATDTRYLRNSMLVSLAVFLPLLFLLVPLWGN 400
|
....*..
gi 1293409500 422 HGLWAAL 428
Cdd:cd13136 401 HGLWLAL 407
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
22-428 |
9.94e-77 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 245.82 E-value: 9.94e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 22 TNRLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELlAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQ 101
Cdd:COG0534 6 ILKLLLRLALPIILGNLLQSLYGLVDTIFVGRLGTAAL-AAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDREEAR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 102 AVFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQT 181
Cdd:COG0534 85 RVLGQALLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIML 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 182 LINGTNIVLSILLGLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNRDIMIRSFA 261
Cdd:COG0534 165 IGNVLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFRKRSLLRLRLRDLRPDRKILKRILRIGLPAGLQQLA 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 262 LLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLGLAASTTL 341
Cdd:COG0534 245 ESLGFLVLNALVARLGTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALGIGLLLAL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 342 VLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGWSRDMRNMMLAAFIGYVAALAVLVP--AF 419
Cdd:COG0534 325 LLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLPLAYLLAflGL 404
|
....*....
gi 1293409500 420 GNHGLWAAL 428
Cdd:COG0534 405 GLTGVWLAL 413
|
|
| PRK10367 |
PRK10367 |
DNA-damage-inducible SOS response protein; Provisional |
22-428 |
1.51e-66 |
|
DNA-damage-inducible SOS response protein; Provisional
Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 219.61 E-value: 1.51e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 22 TNRLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQ 101
Cdd:PRK10367 7 SDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 102 AVFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQT 181
Cdd:PRK10367 87 RALVQPLLLALGAGALIALLRTPLIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 182 LINGTNIVLSILLGLVLGWGVAGVAIGTVAGEVIGALAGFAVVYgRFDRKDAPGWAMIFAGDR--LKKLFGLNRDIMIRS 259
Cdd:PRK10367 167 VGNILNIVLDLWLVMGLHMNVQGAALATVIAEYATLLIGLLMVR-KVLKLRGISLEMLKTAWRgnFRRLLALNRDIMLRS 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 260 FALLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLGLAAST 339
Cdd:PRK10367 246 LLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLF 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 340 TLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGWSRDMRNMMLAAFIGYVAALAVLvPAF 419
Cdd:PRK10367 326 SLVYALAGEHIIALLTSLPQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLTL-PWL 404
|
....*....
gi 1293409500 420 GNHGLWAAL 428
Cdd:PRK10367 405 GNHGLWLAL 413
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
32-372 |
5.29e-44 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 157.41 E-value: 5.29e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 32 PMTLGFLTTPLLGLVDTAVVGRLGKAELlAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAVFWRSLMIA 111
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDL-AAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 112 LVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQTLINGTNIVLS 191
Cdd:TIGR00797 80 LLLGLPVLLVGYFFIDPLLSLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIILN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 192 ILL--GLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNRDIMIRSFALLAAFTLV 269
Cdd:TIGR00797 160 YILifGKFGFLGIVGAALATVISYWLMFLLLLYYIKKAKKIGLKWEGLLKPDWEVLKRLLKLGLPIAFRVILESLSFALL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 270 TRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLGLAASTTLVLLAFGNT 349
Cdd:TIGR00797 240 ALLVARLGSIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILILFREF 319
|
330 340
....*....|....*....|...
gi 1293409500 350 VVNMLTTAPDVRALAYEYMPWAA 372
Cdd:TIGR00797 320 IARLFTNDPEVLELAAIYLIFVA 342
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
22-428 |
4.87e-41 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 151.53 E-value: 4.87e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 22 TNRLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELLAGLAVGAVMFdLIFTTFNFLRAATTGLVAQAYGRGDRREQQ 101
Cdd:cd13133 3 GYREILKIALPLVLSMLSQTVMGFTDRAFLGRLSEVALAASGPAGVLYF-AILMLFFGLSSGVQVFVAQYNGAGRYSRIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 102 AVFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQT 181
Cdd:cd13133 82 RVLWQGLYFSLLLAPLLALLSALAAPLLFLLLGHSPEVQALEVEYFRIRILGAPFSLLGAALRAFFSGIGRTRVVMVANL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 182 LINGTNIVLSILL----GLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMI-FAGDRLKKLFGLNRDIM 256
Cdd:cd13133 162 VMVVVNIVLDYALifgkLGFPAMGIAGAAIATVIAEAVSLLFFLLLLFRRKNRRRFGLRRAWrFDRELLRRILRLGLPSG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 257 IRSFALLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLGLA 336
Cdd:cd13133 242 LQFFLDVGAFTVFFLLIGRLGTTELAATNIVFSINSLAFLPMIGLGIAVSSLVGQALGAGRPDLAMRVTRRGLKLALAYM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 337 ASTTLVLLAFGNTVVNMLTTAPD---VRALAYEYMPWAAVTALTGALAFLMDGVFIGAGWSRDMRNMMLAAFIGYVAALA 413
Cdd:cd13133 322 LLLGILFLLFPELLLSIFTPGADfalIAELAVPLLRFVAAYILFDALALVFAGALRGAGDTRFVMLAELIVAWLYLLPPA 401
|
410
....*....|....*..
gi 1293409500 414 VL--VPAFGNHGLWAAL 428
Cdd:cd13133 402 YLlvVLGAGLAGAWTVE 418
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
24-428 |
7.67e-39 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 145.35 E-value: 7.67e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELlAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAV 103
Cdd:cd13137 1 RRIWSLAWPVILENLLQTLVGLVDVFMVGRLGAEAI-AAVGLATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERARRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 104 FWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQTLI 183
Cdd:cd13137 80 LGQSLLLALLLSLPLALLGLLFAEPLLRLLGADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMIIV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 184 NGTNIVLSILLGLVL----GWGVAGVAIGTVAGEVIGALAGFAVVYGRfdRKDAPGWAMIFAGDR--LKKLFGLNRDIMI 257
Cdd:cd13137 160 NVLNIVLDYVLIFGLwgfpGLGVAGAALATVISRVVGALLLLFLLLRG--RLPIKISFKGFRLDRkiIKKLLRIGLPAGL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 258 RSFALLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLGLAA 337
Cdd:cd13137 238 EQLLRSLGFLVLLAIVASYGTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLFMG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 338 STTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGwsrDMRNMMLAAFIGYV------AA 411
Cdd:cd13137 318 LLGLLLFIFAPPLASLFTPDPEVIELGVLYLRIVALSQPFLAISFVLSGALRGAG---DTRPPLIINLISMWlvrlplAY 394
|
410
....*....|....*..
gi 1293409500 412 LAVLVPAFGNHGLWAAL 428
Cdd:cd13137 395 LLGFVLGLGLTGIWLAM 411
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
24-417 |
4.04e-31 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 124.11 E-value: 4.04e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAV 103
Cdd:cd13138 3 KTLLLFALPLLLSNLLQQLYNLVDLLIVGQFLGVAALAAVSNGSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAKKA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 104 FWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQTLI 183
Cdd:cd13138 83 VGTLLVLFLILGIVLTILGLLFAPPILRLMNTPAEILELAVSYLRICFLGIPFIFGYNAYSAILRGLGDSKTPLYFVIIA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 184 NGTNIVLSILLGLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNRDIMIRSFALL 263
Cdd:cd13138 163 CVLNIILDLLFIAVFHMGVAGAALATVIAQAISVLLALYYLRKKKLPFKLSLKDFRFDKEILKEILKIGLPSALQQSLVS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 264 AAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLGLAASTTLVL 343
Cdd:cd13138 243 ISFLIINSIVNSYGVVASAAYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIGLIIILLV 322
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1293409500 344 LAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGwsrdmrNMMLAAFIGYVAALAVLVP 417
Cdd:cd13138 323 FFFAPQLLGLFTSDPEVIEIGAEYLRIYSIDYILFGILFVFNGLFRGLG------KTKFPMIISILRLWLVRIP 390
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
30-428 |
6.53e-31 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 123.20 E-value: 6.53e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 30 ALPMTLGFLTTPLLGLVDTAVVGRLGKaELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAVFWRSLM 109
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLG-DALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 110 IALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQTLINGTNIV 189
Cdd:cd12082 80 LAILLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNIL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 190 LS---ILLGLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNRDIMIRSFALLAAF 266
Cdd:cd12082 160 LDpllIFGLGPPELGIAGAALATVISYVIGALLLLIYLRKGKKILKFKLSLLKPDLELLRRLLRIGLPSAIQNSLLSLGL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 267 TLVTRIGTSF-GPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLGLAASTTLVLLA 345
Cdd:cd12082 240 LIIVAIVAAFgGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGLLILL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 346 FGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGWSRD--MRNMMLAAFIGYVAALAVLVPAFGNHG 423
Cdd:cd12082 320 FPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKslIVSLLSYWVVRLPLAYVLAYLGLGLYG 399
|
....*
gi 1293409500 424 LWAAL 428
Cdd:cd12082 400 IWLAL 404
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
26-429 |
3.33e-27 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 112.98 E-value: 3.33e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 26 IFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAellaglAVGAV-----MFDLIFTTFNFLRAATTGLVAQAYGRGDRREQ 100
Cdd:cd13134 5 LFALAWPIFIELLLQMLLGTIDTFMLSRYSDN------AVAAVgvanqILFLLILIFSFISTGTSILIAQYLGAKDKKKA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 101 QAVFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFlyRILSGPAAL-ANYAILGFVL-GRGEGTLGLM 178
Cdd:cd13134 79 RQIAGVALLFNLLLGLVFSLLLLFFGAELLRLMGLPPELLALGSTYL--RIVGGSLFLqALSLTLSAILrSHGRTKIPMY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 179 LQTLINGTNIVLSILLGLVLG----WGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNRD 254
Cdd:cd13134 157 VSLIMNILNIVGNYLLIFGWFglpkLGVAGVAISTVISRAVGLVLLFILLFRKLKIRFRLKDLRPFPKKLLKKILKIGLP 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 255 IMIRSFALLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAG-YRPAFDRVLRmTALWSL 333
Cdd:cd13134 237 SAGEELSYNLSQTVITAFIARLGTAALAARTYASNISMFVFLFSLAIGQATQIIVGHLVGAGdFDEAYKRVLK-SLKIGL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 334 GLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGwsrDMRNMMLAAFIGY----- 408
Cdd:cd13134 316 LVSLAVALLLALFREPILGLFTDDPEIIALGKTLLLISILLEPGRAFNIVLIGSLRAAG---DARFPVLIGIISMwgisv 392
|
410 420
....*....|....*....|..
gi 1293409500 409 -VAALAVLVPAFGNHGLWAALN 429
Cdd:cd13134 393 pLAYLLGIVLGLGLLGVWIAFA 414
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
24-428 |
5.04e-26 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 109.52 E-value: 5.04e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAV 103
Cdd:cd13143 4 KLFLKFALPAIIGMLVNGLYNIVDGIFVGHGVGALALAAVNLVFPIIMLLMALGLMIGVGGASLISRRLGAGDREKANRI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 104 FWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVlgRGEGTLGLMLQTLI 183
Cdd:cd13143 84 FSTALLLSLILGLLLTILGLLFLDPLLRLLGASGELLPYAVDYLRIILLGAPFTILSSVLNNLL--RAEGKPKLAMLGML 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 184 --NGTNIVLSILLGLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNRDIMIRSFA 261
Cdd:cd13143 162 igAVLNIILDPLFIFVLGLGIAGAALATVIAQLISLLLLLLYFFRGKSLLKLSLLRFKLSLKIIKEILALGFPSFLMQLS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 262 LLAAFTLVTRIGTSF-GPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLGLAASTT 340
Cdd:cd13143 242 SSVVTIVLNLTLLGYgGDIGVAAFGIVTRILTFLFLPLIGLSQGLQPIIGYNYGAGNYDRVKQALKLALIVALIYGLVLF 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 341 LVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGWSRdmrnmmLAAFIGYVAALAVLVP--- 417
Cdd:cd13143 322 LILLLFPEQIVSLFTDDPELIALAARILRIFLLAFPLAGINIVLSGYFQAIGKAK------RAALLSLLRQGLFLIPlll 395
|
410
....*....|....*
gi 1293409500 418 ----AFGNHGLWAAL 428
Cdd:cd13143 396 ilprLFGLDGIWLAF 410
|
|
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
24-428 |
1.62e-25 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 107.97 E-value: 1.62e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELlAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAV 103
Cdd:cd13131 3 RALLRLALPILIAQLAQMAMGFVDTVMAGRLGADDL-AAVALGSSLWFPVFTFGMGLLLAVTPLVAQAHGAGDRRRIRRA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 104 ----FWRSLMIALVTGGTIVLISPILLsaglwLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFV--LGRGEGTLGL 177
Cdd:cd13131 82 vrqgLWLALLLSLPLMLLLWLAPPILP-----LMGQEPEVAAIARGYLLALAWGIPPALLFQVLRSFLdaLGRTRPAMVI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 178 MLQTLIngTNIVLSILLGL-VLGW---GVAGVAIGTVAGEVIGALAGFAVV--------YGRFDRKDAPGWAMIfagdrl 245
Cdd:cd13131 157 TLLALV--LNIPLNYVLIFgKFGLpalGGAGAGLATAIVYWLMFLALAFYIrrhkrfrrYRLFARFWRPDWARL------ 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 246 KKLFGLNRDIMIRSFALLAAFTLVTRIGTSFGPVTLAANAVLM----TIFLVAGyyldGLATAAEQLTGRSIGAGYRPAF 321
Cdd:cd13131 229 KELLRLGLPIGLTIFFEVSLFAAVALLMGRLGTTVLAAHQIALnfasLLFMVPL----GISMAATVRVGFALGAGDPADA 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 322 DRVLRMTALWSLGLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGwsrDMRNMM 401
Cdd:cd13131 305 RRAGLVGLGLGVGFAALTALLLLLFPEQIAGLYTNDPAVIALAASLLVFAALFQLFDGIQVVAAGALRGYK---DTRVPF 381
|
410 420 430
....*....|....*....|....*....|...
gi 1293409500 402 LAAFIGY------VAALAVLVPAFGNHGLWAAL 428
Cdd:cd13131 382 LLALISYwgiglpLGYLLAFTTGLGAFGVWIGL 414
|
|
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
24-428 |
1.47e-23 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 102.27 E-value: 1.47e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELlAGLAVgAVMFDLIfTTFNFLRAATTG---LVAQAYGRGDRREQ 100
Cdd:cd13132 3 KKLLRLAAPLVLTSLLQYSLSVVSVVFVGHLGKLEL-AAASL-ASSFANV-TGFSILLGLASAldtLCGQAFGAKNYKLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 101 QAVFWRSLMIALVTggtIVLISPILLSAG--LWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEgTLGLM 178
Cdd:cd13132 80 GVYLQRALVILLLC---CVPISLLWLNTEpiLLLLGQDPEIARLAGEYLRWLIPGLFAYALFEPLKRYLQAQGI-VLPLV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 179 LQTLI-NGTNIVLSILLGLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNrdimI 257
Cdd:cd13132 156 YISLVaLLLNILLNYLLVFVLGLGFIGAALATSISYWLIVVLLLLYIFFSKGHKATWGGFSREAFRGWGPFLKLA----I 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 258 RSFALLA----AFTLVTRI-GTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGyRPafdRVLRMTALWS 332
Cdd:cd13132 232 PSALMLClewwAFEILVLLaGLLPGTVALAAQSICLTTTSLLYMIPLGISIAASVRVGNELGAG-NP---KRAKLAAIVA 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 333 LGLAASTTLV----LLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGWSRDMRNMMLAAFIGY 408
Cdd:cd13132 308 LILSLVIGVVvailLLVLRDVWAYLFTSDEEVIALVADLLPILALFQIFDGLQAVLSGVLRGCGRQKLGAYVNLVAYYLI 387
|
410 420
....*....|....*....|...
gi 1293409500 409 ---VAALAVLVPAFGNHGLWAAL 428
Cdd:cd13132 388 glpVGLLLAFVLGLGLKGLWIGL 410
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
24-427 |
1.21e-18 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 87.63 E-value: 1.21e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELlaglAVGAVMFDLIFTTFNF---LRAATTGLVAQAYGRGDRREQ 100
Cdd:cd13142 11 RTLLKLAWPIIVSNLLQVAYNLADTFWLGRLGADAV----AAPSISWPLIFLFISLgggLTVAGTALVAQYTGAGDYDKA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 101 QAVFWRSLMIALVTGGTIVLISPILLSAGL-WLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLML 179
Cdd:cd13142 87 NKVAGQTFSFVIILSLILAVLGYILSRPLLlLLIGAPEEVYPLALAYLRIIFLGLPFMFIFFVFNSLLRGIGDTKTPMKI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 180 QTLINGTNIVLSILL----GLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNRDI 255
Cdd:cd13142 167 MFGSVLLNVILDPLLifgiGPFPGLGVAGAALATVISRGIAAVIGLYLLFKGRVGLKISLRDLKPDWEWLKKIFRIGLPS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 256 MIRSFALLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLGL 335
Cdd:cd13142 247 SIEQSARALGFTVMTALVAGFGTVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAGQIDRAEEIVKKAALLIFLI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 336 AASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGwsrdmrNMMLAAFIGYV------ 409
Cdd:cd13142 327 LVIGGVLAFLFAEPIVRVFINDPEVIKEGADFLRIVAPSFPFFGLFQVINGAFRGSG------HTLTAMIISILrlwvir 400
|
410 420
....*....|....*....|.
gi 1293409500 410 ---AALAVLVPAFGNHGLWAA 427
Cdd:cd13142 401 iplAYLLAYVLGLGVTGIWIA 421
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
24-429 |
1.41e-18 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 87.58 E-value: 1.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELLAglaVGAVMFDLIFTT--FNFLRAATTGLVAQAYGRGDRREQQ 101
Cdd:cd13140 5 KTLLRLALPIMGTSFIQMAYNLTDMFWVGRLGSDAVAA---VGTAGFFVWLAYalALLSKIGAQVKVSQSIGAKDEKEAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 102 AVFWRSLMIALVTGgtivlispILLSAGLWLMGP---------GPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGE 172
Cdd:cd13140 82 KYARNALQLNLLLG--------ILYGLLLLLFAKpligffnlgDAEVISLAITYLRIVALGLIFSFLNPVFTGIFNALGD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 173 GTLGLMLQTLINGTNIVLSILLGLVLG----WGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKL 248
Cdd:cd13140 154 SKTPFIINAIGLVLNIILDPLLIFGFGpfpaLGVAGAALATVLAQAIVFLLFLYALKKKKGLFLKIRILKRPDRKYIKEI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 249 FGLNRDIMIRSfALLAAFTLV-TRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYrpaFDRVL-- 325
Cdd:cd13140 234 LKLGLPVALQS-ILFALISMIlARIIASFGPVAIAAQKVGSQIESISWMTAEGFSTALAAFVGQNYGAGK---YDRIRkg 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 326 -RMTALWSLGLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGwsrdmrNMMLAA 404
Cdd:cd13140 310 yKTALKIASAIGLFATLLLFFFGEPLFSLFIPDPETIAIGVDYLRILGFSQLFMCLEITTTGAFNGLG------RTKPPA 383
|
410 420 430
....*....|....*....|....*....|..
gi 1293409500 405 FIGYV-------AALAVLVPAFGNHGLWAALN 429
Cdd:cd13140 384 IISIVfnglripLALLLSPTGLGLNGIWWAIS 415
|
|
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
24-374 |
1.16e-14 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 75.42 E-value: 1.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELLAGLAVGAVMFDLIFTTFNfLRAATTGLVAQAYGRGDRREQQAV 103
Cdd:cd13149 9 RHLIKLTLPMIFGILAMLIFNLTDTFFVGKLGTKELAAISFTFPVVLFLNSLTIG-LGIGASAVISRAIGAGDRNKAKRL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 104 FWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQTLI 183
Cdd:cd13149 88 ATDSLILSLLLSVIVSLLGLFTIPPLFSLLGASGEILPLIVEYMAIWYLGLVFLVLPMVGNAIIRATGDTKRPSLVMLGA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 184 NGTNIVLSILL----GLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDrkdapgwAMIFAGDRLKKLFGLNRDIMirS 259
Cdd:cd13149 168 ALVNVILDPILifgfGPIPGMGIAGAAIATVISRALGLGAALYFLHYHHR-------LIDFSEPSLKALFRSWKDIL--S 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 260 FALLAAFT---------LVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTAL 330
Cdd:cd13149 239 IGIPAALSniltplsaaFITALVATYGPAAVAAFGVATRIESFAFIIVMALSSALGPFVGQNWGAGQYERVQEGLKISLK 318
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1293409500 331 WSLGLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVT 374
Cdd:cd13149 319 FSLIYGAILGIVLALFAGWLASLFSAEPEVIELITLYLLIVPIG 362
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
23-425 |
3.04e-14 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 74.19 E-value: 3.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 23 NRLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELlAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQA 102
Cdd:cd13144 7 LRLLLTMSIPAMISMLFQALYNIVDSIFVARLGENAL-TAVSLAFPIQNLMIAVAVGTGVGVNALLSRSLGEKDQKEANK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 103 VFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQTL 182
Cdd:cd13144 86 AANNGLLLALLSYLLFLLLGLFGVKPFFRLFTDDPEILEYGYAYLSWCVIFSFGMFFQILCEKVLQSTGNTITPMIAQLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 183 INGTNIVLS-IL---LGLVLGWGVAGVAIGTVAGEVIGALAGFAVVYG---------RFDRKDAPGWAMIFAgdrlkklF 249
Cdd:cd13144 166 GAIINIILDpILifgLFGFPAMGIAGAAIATVIGQILAMFLAFFFLLRknkdvqpdlRLFRPSLRIIKEIYA-------V 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 250 GLNRDIMIRSFALLAAftLVTRIGTSFGPVTLAA--------NAVLMTIFlvagyyldGLATAAEQLTGRSIGAGYRPAF 321
Cdd:cd13144 239 GLPSIIMQAISSVMVF--GLNKILAGFGPTAVAVfgiyfklqSFVFMPVF--------GLNNGLIPIVAYNYGAGNKDRI 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 322 DRVLRMTALWSLGLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGwsRDMRNMm 401
Cdd:cd13144 309 REAIKYAILIAVVIMLAGGLLFQLFPDQLLGLFNASEEMLAIGVPALRIISLSFLFAALSIILSGLFQALG--RGVYSL- 385
|
410 420 430
....*....|....*....|....*....|.
gi 1293409500 402 laaFIGYVAALAVLVPA-------FGNHGLW 425
Cdd:cd13144 386 ---IISVARQLVVLLPLawllakmFGLNGVW 413
|
|
| PRK01766 |
PRK01766 |
multidrug efflux protein; Reviewed |
24-408 |
3.28e-14 |
|
multidrug efflux protein; Reviewed
Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 74.46 E-value: 3.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELlAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRRE---- 99
Cdd:PRK01766 12 RQLLALALPILLAQVAQTAMGFVDTVMAGGVSATDL-AAVAIGTSIWLPVILFGHGLLLALTPIVAQLNGAGRRERiahq 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 100 -QQAvFWRSLMIALVTGGTIVLISPILLSaglwLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEgTLGLM 178
Cdd:PRK01766 91 vRQG-LWLALFLSVLIMLVLYNAVPPILN----MMNLEPEVADIAVGYLHALLWGIPAYLLYQVLRSFIDGLGK-TKPTM 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 179 LQTLIngtnivlSILLGLVLGW------------GVAGVAIGTVAGEVIGALAGFAVV--------YGRFDRKDAPGWAm 238
Cdd:PRK01766 165 VIGFL-------GLLINIPLNYifiygkfgfpelGGVGCGVATAIVYWVMFLAMLIYIkrarrfrdFRLFKGLYKPDWA- 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 239 ifagdRLKKLFGLNRDIMIRSFALLAAFTLVTRIGTSFGPVTLAANAVLM----TIFLVAgyylDGLATAAEQLTGRSIG 314
Cdd:PRK01766 237 -----VIKRLLKLGLPIGLAIFFEVSLFAVVTLLVSPLGTVTVAAHQIALnfssLLFMLP----LSLAMALTIRVGFELG 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 315 AGyRPAFDRVLRMTALWS-LGLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGagw 393
Cdd:PRK01766 308 AG-RTLDARQYAYIGLAVgLGMALLTAIFLVLFREQIALLYTDDPEVVALASHLLLFAALFQFSDAIQVIGSGALRG--- 383
|
410
....*....|....*
gi 1293409500 394 SRDMRNMMLAAFIGY 408
Cdd:PRK01766 384 YKDTRVIFFITFIAY 398
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
26-392 |
3.85e-14 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 73.89 E-value: 3.85e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 26 IFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELLAGLAVGAVMFdLIFTTFNFLRAATTGLVAQAYGRGDRREQQAVFW 105
Cdd:cd13141 13 IISMALPIAIGMIIQTLYFLVDLYFVGQLGDAALAGVSLAGNVMF-FVMALTQVLNVGTAALVSHAVGRKDQGEANAVFN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 106 RSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQTLING 185
Cdd:cd13141 92 QSLLLAAVLGLVVLVLGYLFGRLYLETLAADAATVEAATTYLYWFIPSLALQFILTVLGAALRGTGIVKPFMVIQILAVL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 186 TNIVLSILlgLVLGWGVaGVAIGtVAG----EVIGALAGFAVVYGRFDRKDApgwamIFAGDRlkKLFGLNRDIMIR--- 258
Cdd:cd13141 172 LNIILAPI--LITGWGT-GRALG-VAGaglaSSISVAIAVVLLLYYFLRLEK-----YLRLDL--ALWRPDLPTWKRllk 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 259 -------SFALLAAFTLVTRIGTS-FGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTAL 330
Cdd:cd13141 241 iglpsggEFLLTFVYMAVIYWALRpFGAAAQAGFGIGSRIMQSLFLPAMAIAFAAPAIAGQNFGAGNYDRVRETFRITAI 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1293409500 331 WSLGLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAG 392
Cdd:cd13141 321 LTTALMLVLTLLCQLVPELLVTPFSDDAAVIAVAATFLRYVSWNFVAAGLVFTCSGMFQALG 382
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
23-368 |
2.47e-13 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 71.49 E-value: 2.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 23 NRLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKaellagLAVGAVMFDLIFTTFNF-----LRAATTGLVAQAYGRGDR 97
Cdd:cd13139 13 NRAIFLLAIPMVLEMVMESLFAVVDLYFVSRLGA------LAIATVGLTESVLTIVYsiaigLSMAATALVARRIGEKDP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 98 REQQAVFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGL 177
Cdd:cd13139 87 EGAGFAAVQAILLGVALSLILSILGYFFAEDILSLMGASPAVIAEGYGYTRIMFGGNGFIMLLFLINGIFRGAGDAAIAM 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 178 MLQTLINGTNIVLSIL----LGLVLGWGVAGVAIGTVAGEVIGAL--------AGFAVVYGRFDRKdaPGWAMIfagdrl 245
Cdd:cd13139 167 RSLWLANGLNIILDPLfifgLGPIPAMGVTGAAIATTIGRSIGVLyqlyhlfkGKGRIQIRRRHLK--LDWAII------ 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 246 KKLFGLNRDIMIRSFALLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVL 325
Cdd:cd13139 239 KKIIKIAVGGILQFLIASSSWIFLVRIIAEFGSTALAGYTIAIRIIMFALLPAWGLSNAAATLVGQNLGAGQPDRAEKSV 318
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1293409500 326 RMTALWSLGLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYM 368
Cdd:cd13139 319 WRAGKYNMVFLGIVSLVFFLFAEPLVSFFTTDPEVIAIAVEAL 361
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
26-374 |
1.42e-12 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 69.24 E-value: 1.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 26 IFSIALPMTLGFLTTPLLGLVDTAVVGRLgkaELLAGLAVGAVMFdLIFTTFNFLRAATTG---LVAQAYGRGDRREQQA 102
Cdd:cd13135 3 INHIAIPLILQNLVSQLQMLVDRAFLGRI---SIRYYSAVGNVTT-PFNTITGFLGSISIGftiLGSQSVGAKDIKRIND 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 103 VFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFlyRILSgpaalanyaiLGFVLGRGEGTLGLMLQT- 181
Cdd:cd13135 79 YAISSIVYNSIIGVILFLLWLFGARIIFVLFGVDGQILGYSINYV--RIFS----------IYLLLLGILFTFSSILQGi 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 182 -----------LINGTNIVLSILLglVLG------WGVAGVAIGTVAGEVIGA--LAGFAVVYGRFDRKDAPGWAMIFAG 242
Cdd:cd13135 147 getkpimyggiIKNLLNVILDYVL--IFGnfgfprLGIIGAAIATTIANVLNLiiLVYLCRKIKKLTFKLSNTKVLKANI 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 243 DRLKKLFGLNRDIMIRSFALLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFD 322
Cdd:cd13135 225 RPYKFTIKLGLPLGGEEFLWNIGNLAVIRILNRIGELALGIYTLVFGIENIVLMPMYGYSSAALTLVGESIGKKDLKEAL 304
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1293409500 323 RVLRMTALWSLGLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVT 374
Cdd:cd13135 305 RIGNICLGLGLLIYIAAAIVFLAFPYKILSLFTNDPELINYSIPYLIFIIII 356
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
32-193 |
3.48e-12 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 64.12 E-value: 3.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 32 PMTLGFLTTPLLGLVDTAVVGRLGKAELlAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAVFWRSLMIA 111
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVAL-AAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 112 LVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQTLINGTNIVLS 191
Cdd:pfam01554 80 LLLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNIPLN 159
|
..
gi 1293409500 192 IL 193
Cdd:pfam01554 160 YL 161
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
24-225 |
1.45e-11 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 65.81 E-value: 1.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAV 103
Cdd:cd12082 219 RRLLRIGLPSAIQNSLLSLGLLIIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRI 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 104 FWRSLMIALVTGGTIVLIspILLSAG--LWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTLGLMLQT 181
Cdd:cd12082 299 TWVALLIGLLIGAVLGLL--ILLFPEpiLSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSL 376
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1293409500 182 LINGTNIVLSILLGLVLGWGVAGVAIGTVAGEVIGALAGFAVVY 225
Cdd:cd12082 377 LSYWVVRLPLAYVLAYLGLGLYGIWLALVISLILAALVLLLFFR 420
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
255-406 |
4.67e-11 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 61.04 E-value: 4.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 255 IMIRSFALLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWSLG 334
Cdd:pfam01554 2 IALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGLL 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1293409500 335 LAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVFIGAGWSRDMRNMMLAAFI 406
Cdd:pfam01554 82 LSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLL 153
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
23-368 |
1.11e-09 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 60.30 E-value: 1.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 23 NRLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGkAELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQA 102
Cdd:cd13145 8 PKLIRKLAIPASVGFFFNTMFNVVDTFFAGKIS-TEALAALSLSFPIFFIIIAIGVGIGTGTTALIGNALGAGDRRKARR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 103 VFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEGTlgLMLQTL 182
Cdd:cd13145 87 YAAQGLSFGIILAILLTVIGLFAAPPLFRLLGAEGDYLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDTK--SYRNFL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 183 ING--TNIVLSILL----GLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNRDIM 256
Cdd:cd13145 165 IIGffLNIILDPLFifggGGIPAMGVSGIALATIISQFIGMFYLLYKVRKSGIISGCRLRDFIPRLDVYKEILKQGFPAS 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 257 IRSFALLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGyrpAFDRV---LRMTALWSL 333
Cdd:cd13145 245 LNMMTIGLGIFVITYFVGQFGDEAVAAYGIALRIEQILLLPTIGLNTAVLSIAGQNFGAK---KYDRVretYKKALKYGF 321
|
330 340 350
....*....|....*....|....*....|....*
gi 1293409500 334 GLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYM 368
Cdd:cd13145 322 VIMVVATVFLLFFAEPLMSLFTNDPAVIAIGAGYL 356
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
25-393 |
1.18e-09 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 60.11 E-value: 1.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 25 LIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAE--LLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQA 102
Cdd:cd13146 9 LLIRLALPILIGQLFQLLYNITDTIWISMIDPSDpaLVGGIGLVFPLGMIFLALGNGIQVGVSSLLARAIGAQRAKELDQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 103 VFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGFVlgRGEGTLGLMLQTL 182
Cdd:cd13146 89 AADSGLALALLAATVIVVLGYIFAEPLLQLLGAKGLLLEYALEYFYYSLPGVPFIMLIGVLMGVL--QGEGRTKYMMMAM 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 183 INGT--NIVLSILLGLVLGWGVAGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKLFGLNRDIMIRSF 260
Cdd:cd13146 167 LIGTvvNIVLDPILIFVFDMGVKGAALATVLAQAISLLYLLYVFLIGKSNVTIHIKLSNISSSVIVEILRVGLPQMLLQL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 261 ALLAAFTLVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGyrpAFDRVLR--MTALWsLGLAAS 338
Cdd:cd13146 247 ISSISFLIYNRIIIDIDPVAMTAFTLVGRLDQFILIPIFAISSALLTIAGQNWGRG---NYDRMLQilMTAVI-LGIVVV 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1293409500 339 TTLVLL--AFGNTVVNMLTTAPDVRALAYEYMPWAAVTALTGALAFLMDGVF--IGAGW 393
Cdd:cd13146 323 LVLVLGyvLVAPWLFSLFTTVPEVVAYAVLQVRTMALALPFVAISILVTEFFqaIGKAW 381
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
24-224 |
5.79e-08 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 54.89 E-value: 5.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGkAELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAV 103
Cdd:cd13142 237 KKIFRIGLPSSIEQSARALGFTVMTALVAGFG-TVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAGQIDRAEEI 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 104 FWRSLMIA---LVTGGTIVLISPILLSAglwLMGPGPEVAEVTRTYFLYRILSGPAALANYAILGfvLGRGEG-TLGLML 179
Cdd:cd13142 316 VKKAALLIfliLVIGGVLAFLFAEPIVR---VFINDPEVIKEGADFLRIVAPSFPFFGLFQVING--AFRGSGhTLTAMI 390
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1293409500 180 QTLIN--GTNIVLSILLGLVLGWGVAGVAIGTVAGEVIGALAGFAVV 224
Cdd:cd13142 391 ISILRlwVIRIPLAYLLAYVLGLGVTGIWIAMAISNIVAALIALAWF 437
|
|
| MATE_like_3 |
cd13148 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
24-372 |
1.35e-06 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240553 [Multi-domain] Cd Length: 441 Bit Score: 50.35 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGkAELLAGLAVGAVMFDLIFTTFN-FLRAATTGLVAQAYGRGDRREQQA 102
Cdd:cd13148 12 PTLLRLALPNILALLVQTLVGLAETYFVGQLG-TDALAGVALVFPLLMLTQMMSNgAMGGGVSSAIARALGAGDRERAEA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 103 VFWRSLMIALVTGGTIVLISPILLSAGLWLMGPGPEVAEVTRTYFLYrILSGPAALANYAILGFVLgRGEGTLGLMLQTL 182
Cdd:cd13148 91 LVWHALVIALAGGLVFSLLFLLFGPALYRLLGGRGEALDAALAYSNV-LFSGAILIWLVNLLAAAL-RGTGNMRVPALVT 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 183 INGTNIVLSILLGLVLGWGvaGVAIGTVAGEVIGALAGFAVVYGRFDRKDAPGWAMIFAGDRLKKL-FGLNRDIMirSFA 261
Cdd:cd13148 169 LVGAVVQIPLSPGLILGWG--PLPRLGVAGAAVAAVLYYALAALVLLRYLASGRSRLRLRLRALRLeRRLFRDIL--RVG 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 262 LLAAFT---------LVTRIGTSFGPVTLAANAVLMTIFLVAGYYLDGLATAAEQLTGRSIGAGYRPAFDRVLRMTALWS 332
Cdd:cd13148 245 LLAALSplqtnltvlLLTGLVGRFGTAALAGYGIGSRLEFLLIPLVFGLGAAMTAMVGMNIGAGQIARARRIAWTGALMA 324
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1293409500 333 LGLAASTTLVLLAFGNTVVNMLTTAPDVRALAYEYMPWAA 372
Cdd:cd13148 325 AVLAGAIGLVLALFPELWLGLFTHDPAVLAAGASYLRIVG 364
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
26-218 |
3.16e-06 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 49.08 E-value: 3.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 26 IFSIALPMTLGFLTTPLLGLVDTAVVGRLGkAELLAglAVGAVM--FDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAV 103
Cdd:cd13147 11 IIKLSIPMIIAMLLQTLYNLVDAIWVAGLG-ADALA--AIGFVFplFMIIIGLGNGLGAGASSAISRRIGAKDKEGADNA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 104 FWRSLMIALVTGGTIVLISPILLSAGLWLMGPGpEVAEVTRTYFLYRILSGPAALAN---YAILgfvlgRGEG-----TL 175
Cdd:cd13147 88 AVHSILLGLIISIILTIVLLPFLEPILVLMGAG-EVLDLAVDYGRIIFLGSIFLIFNnvaYGIL-----RGEGdtkraMY 161
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1293409500 176 GLMLQTLINgtnIVLSILLGLVLGWGVAGVAIGTVAGEVIGAL 218
Cdd:cd13147 162 AMVAGSILN---IILDPIFIYTLGLGIAGAAWATVISMLISSL 201
|
|
| PRK10189 |
PRK10189 |
EmmdR/YeeO family multidrug/toxin efflux MATE transporter; |
24-219 |
6.02e-05 |
|
EmmdR/YeeO family multidrug/toxin efflux MATE transporter;
Pssm-ID: 182293 [Multi-domain] Cd Length: 478 Bit Score: 45.11 E-value: 6.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 24 RLIFSIALPMTLGFLTTPLLGLVDTAVVGRLGKaELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGDRREQQAV 103
Cdd:PRK10189 29 REITPLAVPIFIENLCVLLMGVLSTFLVSWLGK-EAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 104 FWRSLMIalvtggtIVLISpILLSAGLWLMGPG----------PEVAEVTRTYFLYRILSGPAALANYAILGFVLGRGEG 173
Cdd:PRK10189 108 ARQSLVI-------MTLFA-VLLAVLIHFFGEQiidlvagdatPEVKALALTYLELTVWSYPAAAITLIGSGALRGAGNT 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1293409500 174 TLGLMLQTLINGTNIVLS-ILLGLVLGW---GVAGVAIGTVAGEVIGALA 219
Cdd:PRK10189 180 KIPLLINGGMNILNIIISsILIYGLFSWqglGFVGAGLGLTISRYIGAVA 229
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
26-222 |
8.59e-04 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 41.37 E-value: 8.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 26 IFSIALPMTLGFLTTPLLGLVDTAVVGRLGKAELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYG-RGDRREQQAVF 104
Cdd:cd13147 232 ILKVGIPASLEQLIMSVLMIILNLILVIVAGTDGVAVYTAGWRIVSFAIIPLIGIATAVTSVTGAAYGaRNYEKLKTAYN 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 105 WR---SLMIALVTGGTIVLISPIL--------LSAGLwlmgpGPEVAEVTRTYFLYRILSGPAALANYAILGFvlGRGEG 173
Cdd:cd13147 312 YSiklGLIIELIIAILIFIFAPQIaylftyseESAHL-----APEIVAFLRIMCLFLPFVPFGMMSSSMFQGI--GKGLT 384
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1293409500 174 TLGL-MLQTLIngTNIVLSILLGLVLGWGVAGVAIGTVAGEVIGALAGFA 222
Cdd:cd13147 385 SLIItILRELI--FQVLFAYLFAIVLGLGLFGVWWGIVLGNAIGSIVGYL 432
|
|
| PRK00187 |
PRK00187 |
NorM family multidrug efflux MATE transporter; |
26-129 |
6.97e-03 |
|
NorM family multidrug efflux MATE transporter;
Pssm-ID: 166843 [Multi-domain] Cd Length: 464 Bit Score: 38.57 E-value: 6.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1293409500 26 IFSIALPMTLGFLTTPLLGLVDTAVVGRLGkAELLAGLAVGAVMFDLIFTTFNFLRAATTGLVAQAYGRGD----RREQQ 101
Cdd:PRK00187 12 ILRLAGPLIASQLAHMLMVFTDTLMMGRLG-PEALAGGGLGAASYSFVSIFCVGVIAAVGTLVAIRHGAGDiegaTRLAQ 90
|
90 100
....*....|....*....|....*...
gi 1293409500 102 AVFWRSLMIALVTGGTIVLISPILLSAG 129
Cdd:PRK00187 91 AGLWLAWLLALVAALLLWNLKPLLLLFG 118
|
|
| |
