|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
218-437 |
3.55e-28 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 111.54 E-value: 3.55e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 218 IEVKNKEIIKLEQMKYDFLRGSSHELKTPLSRMKIILENMKYNIGKYK-DRDLYIDKCLDITNELTYNISQILTFSSLEY 296
Cdd:COG2205 2 LEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLSPeERRELLEIIRESAERLLRLIEDLLDLSRLES 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 297 --LKDDEEWVTIKSVLDAVLVKYDELAMRNHLTFNSTIQSEQLLIG--KKALNLVLSNLISNAVKYSEPNSVITIDIKND 372
Cdd:COG2205 82 gkLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYadPELLEQVLANLLDNAIKYSPPGGTITISARRE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 373 ----WLCVTN----MthSEVNLKPLMDiKF----DLNKEGSHGLGLYIIKTLLKNYGIEYAVENTDR---TFTFKIKLNE 437
Cdd:COG2205 162 gdgvRISVSDngpgI--PEEELERIFE-RFyrgdNSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGggtTFTVTLPLAE 238
|
|
| ArsS_fam_HK |
NF038389 |
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase ... |
14-432 |
2.69e-14 |
|
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase participating in a two-component system that controls the response to acid conditiions encountered during the process of gastric colonization. This HMM identified ArsS itself but also a broader collection of apparent orthologs from closely related non-gastric colonizers such as Helicobacter hepaticus, Campylobacter jejuni and Wolinella succinogenes. See BlastRule NBR014349 for specific identification of ArsS itself, distinguished by a signature His residue that becomes protonated at low pH.
Pssm-ID: 468500 [Multi-domain] Cd Length: 402 Bit Score: 74.11 E-value: 2.69e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 14 IFSVLVLFIMIIHLL--VFFMFPKSYLETRKHELTVKANEIAeyldgkdlNYITQSLEFFSSSNDIKAFIKKgvNANELA 91
Cdd:NF038389 4 FFKITILFAIALVSVsaLFLILLKYQKENYNEELNKKYSLIA--------NTLLQLYQKNINEEELEKYLKN--FGFMPI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 92 IDEGIDVNLNSNTNSLIVEDRAIHSSS-----GVELMINFVSTADMLKEAKSISFKFlPLSVIFSIAVSIIIAFIYAKMI 166
Cdd:NF038389 74 TDKKLEKEILEIGKNKFILKENGSFRIlkyndKIYLLIKNDGFSLLLEDNEKKSYRY-YYIIVFFIFLILLLLILYISVL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 167 K------HNIGEIKDVTDQMMQLDRqaylKVNSADEIAELKlqiNELYRSLlssiddievknKEIIKLEQMKYDFLRGSS 240
Cdd:NF038389 153 KslkplkKLKKQIKKFANGDFDFIK----SESNGDEIGEVA---NEFDKAV-----------KKIKALNESRQLFLRNIM 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 241 HELKTPLSRMKIILENMKYNigKYKDRDLYIDKCLDI-TNELTyNISQIltfSSLEYLKDDEEwVTIKSVLDAVLvkydE 319
Cdd:NF038389 215 HELKTPITKGRIVAEMLEDE--KQKERLISIFERLESlINEFA-KIEQL---TSKNYKLNKKE-YRLSDIIDEAI----D 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 320 LAMRNHLTFNSTIQSEQLLIGK--KALNLVLSNLISNAVKYSePNSVITIDIKNDWLCVTNMthSEVNLKPLMD-----I 392
Cdd:NF038389 284 MLMIDDSSVIIKVSLEDFKLNVdfELFSLAIKNLIDNAIKYS-PDKKVTIEIKGDKIEFKNK--GEPLEEPLEYyfepfF 360
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1328117890 393 KFDLNKEGSHGLGLYIIKTLLK--NYGIEYAVENTDRTFTFK 432
Cdd:NF038389 361 KGNEKSKSGFGLGLYIVKNILKahGFKLEYEYENGYNIFIIK 402
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
342-435 |
2.93e-11 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 59.97 E-value: 2.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 342 KALNLVLSNLISNAVKYSEPNSVITIDIK--NDWLCVT--------NMTHSEVNLKPLMDIKFDLNKEGSHGLGLYIIKT 411
Cdd:smart00387 4 DRLRQVLSNLLDNAIKYTPEGGRITVTLErdGDHVEITvedngpgiPPEDLEKIFEPFFRTDKRSRKIGGTGLGLSIVKK 83
|
90 100
....*....|....*....|....*..
gi 1328117890 412 LLKNYGIEYAVENTDR---TFTFKIKL 435
Cdd:smart00387 84 LVELHGGEISVESEPGggtTFTITLPL 110
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
342-435 |
3.26e-09 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 54.30 E-value: 3.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 342 KALNLVLSNLISNAVKYSEPNSVITIDIK-NDWLCVT---NMTHSEVNLKPLMDIKF---DLNKEGSHGLGLYIIKTLLK 414
Cdd:pfam02518 4 LRLRQVLSNLLDNALKHAAKAGEITVTLSeGGELTLTvedNGIGIPPEDLPRIFEPFstaDKRGGGGTGLGLSIVRKLVE 83
|
90 100
....*....|....*....|....
gi 1328117890 415 NYGIEYAVENTDR---TFTFKIKL 435
Cdd:pfam02518 84 LLGGTITVESEPGggtTVTLTLPL 107
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
347-435 |
1.24e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 52.39 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 347 VLSNLISNAVKYSEPNSVITID--IKNDWLCVT--NMTHSEVNLKP--LMDiKF-----DLNKEGShGLGLYIIKTLLKN 415
Cdd:cd16923 4 VFSNLLSNAIKYSPENTRIYITsfLTDDVVNIMfkNPSSHPLDFKLekLFE-RFyrgdnSRNTEGA-GLGLSIAKAIIEL 81
|
90 100
....*....|....*....|
gi 1328117890 416 YGIEYAVENTDRTFTFKIKL 435
Cdd:cd16923 82 HGGSASAEYDDNHDLFKVRL 101
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
227-368 |
6.40e-06 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 48.08 E-value: 6.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 227 KLEQMKYDFLRGSSHELKTPLSRMKIILENMkynigkyKDRDL---YIDKCLDITNELTYN----ISQILTFSSLEY--L 297
Cdd:PRK11006 199 QLEGARRNFFANVSHELRTPLTVLQGYLEMM-------QDQPLegaLREKALHTMREQTQRmeglVKQLLTLSKIEAapT 271
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1328117890 298 KDDEEWVTIKSVLDAVLVKYDELAMRNH-LTFNStiqSEQLLI--GKKALNLVLSNLISNAVKYSEPNSVITID 368
Cdd:PRK11006 272 IDLNEKVDVPMMLRVLEREAQTLSQGKHtITFEV---DNSLKVfgNEDQLRSAISNLVYNAVNHTPEGTHITVR 342
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
10-356 |
1.78e-05 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 47.03 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 10 MFIQIFSVLVLFIMIIHLLVFFMFPKSYLETRKHELTVKANEIAEYLDGKDLNYITQSLEFFSSSNDIKAFIKKGVNANE 89
Cdd:COG2770 85 VALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAAL 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 90 LAIDEGIDVNLNSNTNSLIVEDRAIHSSSGVELMINFVSTADMLKEAKSISfkflpLSVIFSIAVSIIIAFIYAKMIKHN 169
Cdd:COG2770 165 ALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLL-----LLALLALLLALLLALLLARRITRP 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 170 IGEIKDVTDQMMQLDRQAYLKVNSADEIAELKLQINELYRSLLSSIDDIEVKNKEIIKLEQMkyDFLRGSSHELKTPLSR 249
Cdd:COG2770 240 LRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELAR--LLEALLELLLALLLLL 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 250 MKIILENMKYNIGKYKDRDLYIDKCLDITNELTYNISQILTFSSLEYLKDDEEWVTIKSVLDAVLVKYDELAMRNHLTFN 329
Cdd:COG2770 318 LALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAA 397
|
330 340
....*....|....*....|....*..
gi 1328117890 330 STIQSEQLLIGKKALNLVLSNLISNAV 356
Cdd:COG2770 398 LAAALLLLELALEELVLALLALALLAL 424
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
218-437 |
3.55e-28 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 111.54 E-value: 3.55e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 218 IEVKNKEIIKLEQMKYDFLRGSSHELKTPLSRMKIILENMKYNIGKYK-DRDLYIDKCLDITNELTYNISQILTFSSLEY 296
Cdd:COG2205 2 LEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLSPeERRELLEIIRESAERLLRLIEDLLDLSRLES 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 297 --LKDDEEWVTIKSVLDAVLVKYDELAMRNHLTFNSTIQSEQLLIG--KKALNLVLSNLISNAVKYSEPNSVITIDIKND 372
Cdd:COG2205 82 gkLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYadPELLEQVLANLLDNAIKYSPPGGTITISARRE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 373 ----WLCVTN----MthSEVNLKPLMDiKF----DLNKEGSHGLGLYIIKTLLKNYGIEYAVENTDR---TFTFKIKLNE 437
Cdd:COG2205 162 gdgvRISVSDngpgI--PEEELERIFE-RFyrgdNSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGggtTFTVTLPLAE 238
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
194-436 |
4.88e-24 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 101.91 E-value: 4.88e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 194 ADEIAELKLQINELYRSLLSSIDDIEVKNKEIIKLEQMKYDFLRGSSHELKTPLSRMKIILENMKYNIGKykDRDLYIDK 273
Cdd:COG0642 72 LLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEELDE--EQREYLET 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 274 CLDITNELTYNISQILTFSSLE--YLKDDEEWVTIKSVLDAVLVKYDELAMRNHLTFNSTIQSEQLLI--GKKALNLVLS 349
Cdd:COG0642 150 ILRSADRLLRLINDLLDLSRLEagKLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVrgDPDRLRQVLL 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 350 NLISNAVKYSEPNSVITIDIKND----WLCVTN----MTHSEVN--LKPLMDIKFDLNKEGShGLGLYIIKTLLKNYGIE 419
Cdd:COG0642 230 NLLSNAIKYTPEGGTVTVSVRREgdrvRISVEDtgpgIPPEDLEriFEPFFRTDPSRRGGGT-GLGLAIVKRIVELHGGT 308
|
250 260
....*....|....*....|
gi 1328117890 420 YAVENTDR---TFTFKIKLN 436
Cdd:COG0642 309 IEVESEPGkgtTFTVTLPLA 328
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
100-437 |
1.40e-23 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 101.55 E-value: 1.40e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 100 LNSNTNSLIVEDRAIHSSSGVELMINFVSTADMLKEAKSISFKFLPLSVIFSIAVSIIIAFIYAKMIKHNIGEIKDVTDQ 179
Cdd:COG5002 39 LLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALL 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 180 MMQLDRQAYLKVNSADEIAELKLQINELYRSLLSSidDIEvknkEIIKLEQMKYDFLRGSSHELKTPLSRMKIILENMKY 259
Cdd:COG5002 119 LLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVER--DIT----ELERLEQMRREFVANVSHELRTPLTSIRGYLELLLD 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 260 NIGK-YKDRDLYIDKCLDITNELTYNISQILTFSSLEY--LKDDEEWVTIKSVLDAVLVKYDELAMRNHLTFNSTIQSEQ 336
Cdd:COG5002 193 GAADdPEERREYLEIILEEAERLSRLVNDLLDLSRLESgeLKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDP 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 337 LLI--GKKALNLVLSNLISNAVKYSEPNSVITIDIKND----WLCVTNmtH----SEVNLKPLMDiKF-------DLNKE 399
Cdd:COG5002 273 LLVlgDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEddqvRISVRD--TgigiPEEDLPRIFE-RFyrvdksrSRETG 349
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1328117890 400 GShGLGLYIIKTLLKNYGIEYAVENTDR---TFTFKIKLNE 437
Cdd:COG5002 350 GT-GLGLAIVKHIVEAHGGRIWVESEPGkgtTFTITLPLAR 389
|
|
| ArsS_fam_HK |
NF038389 |
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase ... |
14-432 |
2.69e-14 |
|
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase participating in a two-component system that controls the response to acid conditiions encountered during the process of gastric colonization. This HMM identified ArsS itself but also a broader collection of apparent orthologs from closely related non-gastric colonizers such as Helicobacter hepaticus, Campylobacter jejuni and Wolinella succinogenes. See BlastRule NBR014349 for specific identification of ArsS itself, distinguished by a signature His residue that becomes protonated at low pH.
Pssm-ID: 468500 [Multi-domain] Cd Length: 402 Bit Score: 74.11 E-value: 2.69e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 14 IFSVLVLFIMIIHLL--VFFMFPKSYLETRKHELTVKANEIAeyldgkdlNYITQSLEFFSSSNDIKAFIKKgvNANELA 91
Cdd:NF038389 4 FFKITILFAIALVSVsaLFLILLKYQKENYNEELNKKYSLIA--------NTLLQLYQKNINEEELEKYLKN--FGFMPI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 92 IDEGIDVNLNSNTNSLIVEDRAIHSSS-----GVELMINFVSTADMLKEAKSISFKFlPLSVIFSIAVSIIIAFIYAKMI 166
Cdd:NF038389 74 TDKKLEKEILEIGKNKFILKENGSFRIlkyndKIYLLIKNDGFSLLLEDNEKKSYRY-YYIIVFFIFLILLLLILYISVL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 167 K------HNIGEIKDVTDQMMQLDRqaylKVNSADEIAELKlqiNELYRSLlssiddievknKEIIKLEQMKYDFLRGSS 240
Cdd:NF038389 153 KslkplkKLKKQIKKFANGDFDFIK----SESNGDEIGEVA---NEFDKAV-----------KKIKALNESRQLFLRNIM 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 241 HELKTPLSRMKIILENMKYNigKYKDRDLYIDKCLDI-TNELTyNISQIltfSSLEYLKDDEEwVTIKSVLDAVLvkydE 319
Cdd:NF038389 215 HELKTPITKGRIVAEMLEDE--KQKERLISIFERLESlINEFA-KIEQL---TSKNYKLNKKE-YRLSDIIDEAI----D 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 320 LAMRNHLTFNSTIQSEQLLIGK--KALNLVLSNLISNAVKYSePNSVITIDIKNDWLCVTNMthSEVNLKPLMD-----I 392
Cdd:NF038389 284 MLMIDDSSVIIKVSLEDFKLNVdfELFSLAIKNLIDNAIKYS-PDKKVTIEIKGDKIEFKNK--GEPLEEPLEYyfepfF 360
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1328117890 393 KFDLNKEGSHGLGLYIIKTLLK--NYGIEYAVENTDRTFTFK 432
Cdd:NF038389 361 KGNEKSKSGFGLGLYIVKNILKahGFKLEYEYENGYNIFIIK 402
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
342-435 |
2.93e-11 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 59.97 E-value: 2.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 342 KALNLVLSNLISNAVKYSEPNSVITIDIK--NDWLCVT--------NMTHSEVNLKPLMDIKFDLNKEGSHGLGLYIIKT 411
Cdd:smart00387 4 DRLRQVLSNLLDNAIKYTPEGGRITVTLErdGDHVEITvedngpgiPPEDLEKIFEPFFRTDKRSRKIGGTGLGLSIVKK 83
|
90 100
....*....|....*....|....*..
gi 1328117890 412 LLKNYGIEYAVENTDR---TFTFKIKL 435
Cdd:smart00387 84 LVELHGGEISVESEPGggtTFTITLPL 110
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
11-437 |
3.70e-11 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 64.81 E-value: 3.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 11 FIQIFSVLVLFIMIIHLLVFFMFPKSYLETRKHELTVKANEIAEYLDGKDLNYITQSLEFFSSSNDIKAFIKKGVNANEL 90
Cdd:COG4251 68 LLLLLLVLAALALLLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLAL 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 91 AIDEGIDVNLNSNTNSLIVEDRAIHSSSGVELMINFVSTADMLKEAKSISFKFLPLSVIFSIAVSIIIAFIYAKMIKHNI 170
Cdd:COG4251 148 ALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGL 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 171 GEIKDVTDQMMQLDRQAYLKVNSADEIAELKLQINELYRSLLSSIDDIEVKNKEiikLEQmkydFLRGSSHELKTPLSRM 250
Cdd:COG4251 228 LLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAELERSNEE---LEQ----FAYVASHDLREPLRKI 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 251 ----KIILEnmkynigKYKDR-----DLYIDKCLDITNELTYNISQILTFSSLEYLKDDEEWVTIKSVLDAVLvkyDELA 321
Cdd:COG4251 301 sgfsQLLEE-------DYGDKldeegREYLERIRDAAERMQALIDDLLAYSRVGRQELEFEPVDLNELLEEVL---EDLE 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 322 MRNHLTfNSTIQSEQL--LIG-KKALNLVLSNLISNAVKYSEPNSVITIDI-----KNDW-LCVT------NMTHSEvnl 386
Cdd:COG4251 371 PRIEER-GAEIEVGPLptVRGdPTLLRQVFQNLISNAIKYSRPGEPPRIEIgaereGGEWvFSVRdngigiDPEYAE--- 446
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1328117890 387 kplmDIkFDL-------NKEGSHGLGLYIIKTLLKNYGIEYAVENTDR---TFTFKIKLNE 437
Cdd:COG4251 447 ----KI-FEIfqrlhsrDEYEGTGIGLAIVKKIVERHGGRIWVESEPGegaTFYFTLPKAP 502
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
342-435 |
3.26e-09 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 54.30 E-value: 3.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 342 KALNLVLSNLISNAVKYSEPNSVITIDIK-NDWLCVT---NMTHSEVNLKPLMDIKF---DLNKEGSHGLGLYIIKTLLK 414
Cdd:pfam02518 4 LRLRQVLSNLLDNALKHAAKAGEITVTLSeGGELTLTvedNGIGIPPEDLPRIFEPFstaDKRGGGGTGLGLSIVRKLVE 83
|
90 100
....*....|....*....|....
gi 1328117890 415 NYGIEYAVENTDR---TFTFKIKL 435
Cdd:pfam02518 84 LLGGTITVESEPGggtTVTLTLPL 107
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
347-435 |
1.24e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 52.39 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 347 VLSNLISNAVKYSEPNSVITID--IKNDWLCVT--NMTHSEVNLKP--LMDiKF-----DLNKEGShGLGLYIIKTLLKN 415
Cdd:cd16923 4 VFSNLLSNAIKYSPENTRIYITsfLTDDVVNIMfkNPSSHPLDFKLekLFE-RFyrgdnSRNTEGA-GLGLSIAKAIIEL 81
|
90 100
....*....|....*....|
gi 1328117890 416 YGIEYAVENTDRTFTFKIKL 435
Cdd:cd16923 82 HGGSASAEYDDNHDLFKVRL 101
|
|
| HATPase_AgrC-ComD-like |
cd16935 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
309-435 |
1.77e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Staphylococcus aureus AgrC which is an HK of the accessory gene regulator (agr) quorum sensing two-component regulatory system (TCS) AgrC-AgrA. The agr system plays a part in the transition from persistent to virulent phenotype. This family also includes Streptococcus pneumoniae ComD HK of the ComD-ComE TCS, involved in quorum sensing and genetic competence.
Pssm-ID: 340412 [Multi-domain] Cd Length: 134 Bit Score: 52.96 E-value: 1.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 309 VLDAVLVKYDELAMRNHLTFNSTIQSEQLLiGKKALNL--VLSNLISNAV----KYSEPNSVI--TIDIKNDWLCVTNMT 380
Cdd:cd16935 1 ALDSLLSEKLELAREKGIEFTIEIDIPILL-PISPLDLciIFGNLLDNAIeacaKIDKENRFIhlKIRQKKGFLIISIEN 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1328117890 381 HSEVNLKPLMDIKFDLNKEGSHGLGLYIIKTLLKNYGIEYAVENTDRTFTFKIKL 435
Cdd:cd16935 80 SYEGELKKKNGLFLSTKKDKNHGIGLKSIREIVKKYNGNLSIEYENGIFTLSILL 134
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
212-435 |
5.12e-07 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 51.39 E-value: 5.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 212 LSSIDDIEVKNKEIIKLEQMkYDFLRGSSHELKTplsRMKIILENMkyNIGKYKDRDLYIDKcldITNELtynisQILTF 291
Cdd:COG3290 170 FRDRTELERLEEELEGVKEL-AEALRAQRHDFRN---HLHTISGLL--QLGEYDEALEYIDE---ISEEL-----QELID 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 292 SSLEYLKDdeewvtikSVLDAVLVKYDELAMRNHLTFNSTIQS--EQLLIGKKALNLVLSNLISNAV----KYSEPNSVI 365
Cdd:COG3290 236 SLLSRIGN--------PVLAALLLGKAARARERGIDLTIDIDSdlPDLPLSDTDLVTILGNLLDNAIeaveKLPEEERRV 307
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1328117890 366 TIDI--KNDWLC--VTNmTHSEVNLKPLMDIkFDLN----KEGSHGLGLYIIKTLLKNYGIEYAVENTDRTFT-FKIKL 435
Cdd:COG3290 308 ELSIrdDGDELVieVED-SGPGIPEELLEKI-FERGfstkLGEGRGLGLALVKQIVEKYGGTIEVESEEGEGTvFTVRL 384
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
229-292 |
1.02e-06 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 45.67 E-value: 1.02e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1328117890 229 EQMKYDFLRGSSHELKTPLSRMKIILENMKYNIGKYKDRDLYIDKCLDITNELTYNISQILTFS 292
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLS 64
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
227-368 |
6.40e-06 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 48.08 E-value: 6.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 227 KLEQMKYDFLRGSSHELKTPLSRMKIILENMkynigkyKDRDL---YIDKCLDITNELTYN----ISQILTFSSLEY--L 297
Cdd:PRK11006 199 QLEGARRNFFANVSHELRTPLTVLQGYLEMM-------QDQPLegaLREKALHTMREQTQRmeglVKQLLTLSKIEAapT 271
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1328117890 298 KDDEEWVTIKSVLDAVLVKYDELAMRNH-LTFNStiqSEQLLI--GKKALNLVLSNLISNAVKYSEPNSVITID 368
Cdd:PRK11006 272 IDLNEKVDVPMMLRVLEREAQTLSQGKHtITFEV---DNSLKVfgNEDQLRSAISNLVYNAVNHTPEGTHITVR 342
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
10-356 |
1.78e-05 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 47.03 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 10 MFIQIFSVLVLFIMIIHLLVFFMFPKSYLETRKHELTVKANEIAEYLDGKDLNYITQSLEFFSSSNDIKAFIKKGVNANE 89
Cdd:COG2770 85 VALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAAL 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 90 LAIDEGIDVNLNSNTNSLIVEDRAIHSSSGVELMINFVSTADMLKEAKSISfkflpLSVIFSIAVSIIIAFIYAKMIKHN 169
Cdd:COG2770 165 ALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLL-----LLALLALLLALLLALLLARRITRP 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 170 IGEIKDVTDQMMQLDRQAYLKVNSADEIAELKLQINELYRSLLSSIDDIEVKNKEIIKLEQMkyDFLRGSSHELKTPLSR 249
Cdd:COG2770 240 LRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELAR--LLEALLELLLALLLLL 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 250 MKIILENMKYNIGKYKDRDLYIDKCLDITNELTYNISQILTFSSLEYLKDDEEWVTIKSVLDAVLVKYDELAMRNHLTFN 329
Cdd:COG2770 318 LALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAA 397
|
330 340
....*....|....*....|....*..
gi 1328117890 330 STIQSEQLLIGKKALNLVLSNLISNAV 356
Cdd:COG2770 398 LAAALLLLELALEELVLALLALALLAL 424
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
215-433 |
4.57e-05 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 45.88 E-value: 4.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 215 IDDIEVKNKEIIKLEQMKYDFLRGSSHELKTPLSRMKIILENMKYNIGKYKDRDLYIDKCLDITNELTYNISQILTFSSL 294
Cdd:PRK09959 695 IHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKI 774
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 295 EY--LKDDEEWVTIKSVLDAVLVKYDELAMRNH--LTFNSTIQSEQLL-IGKKALNLVLSNLISNAVKYSEPNSV-ITID 368
Cdd:PRK09959 775 ESgnYQLQPQWVDIPTLVQNTCHSFGAIAASKSiaLSCSSTFPDHYLVkIDPQAFKQVLSNLLSNALKFTTEGAVkITTS 854
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 369 IK--NDWLCVTNMThsevnlkpLMDIKFDLNKEGSH------------------GLGLYIIKTLLKNYGIEYAVEN---T 425
Cdd:PRK09959 855 LGhiDDNHAVIKMT--------IMDSGSGLSQEEQQqlfkrysqtsagrqqtgsGLGLMICKELIKNMQGDLSLEShpgI 926
|
....*...
gi 1328117890 426 DRTFTFKI 433
Cdd:PRK09959 927 GTTFTITI 934
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
341-432 |
8.23e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 41.50 E-value: 8.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 341 KKALNLVLSNLISNAVKYSEPNSVITIDIKND----WLCV--TNMTHSEVNLKPLMDIKF----DLNKEGSHGLGLYIIK 410
Cdd:cd16948 3 AKWLSFIIGQIVSNALKYSKQGGKIEIYSETNeqgvVLSIkdFGIGIPEEDLPRVFDKGFtgenGRNFQESTGMGLYLVK 82
|
90 100
....*....|....*....|....*..
gi 1328117890 411 TLLKNYGIEYAVEN-----TDRTFTFK 432
Cdd:cd16948 83 KLCDKLGHKIDVESevgegTTFTITFP 109
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
175-377 |
3.02e-04 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 43.03 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 175 DVTDQMMQLDRQAYLKVNSADEIaELKLQINELY-RSLLSSIDDIEvknkEIIKLEQMK--YDFLRGSSHELKTPLSRMK 251
Cdd:COG5000 146 ELLREALERGWQEEIELTRDGRR-TLLVRASPLRdDGYVIVFDDIT----ELLRAERLAawGELARRIAHEIKNPLTPIQ 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 252 IILENMKYNIGKYKDRDL-YIDKCLDITNELTYNISQI----LTFSSLEYLKDdeEWVTIKSVLDAVLVKYDELAMRNHL 326
Cdd:COG5000 221 LSAERLRRKLADKLEEDReDLERALDTIIRQVDRLKRIvdefLDFARLPEPQL--EPVDLNELLREVLALYEPALKEKDI 298
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1328117890 327 TFNSTIQSEQLLI--GKKALNLVLSNLISNAVKYSEPNSVITIDIK--NDWLCVT 377
Cdd:COG5000 299 RLELDLDPDLPEVlaDRDQLEQVLINLLKNAIEAIEEGGEIEVSTRreDGRVRIE 353
|
|
| HATPase_c_5 |
pfam14501 |
GHKL domain; This family represents the structurally related ATPase domains of histidine ... |
347-435 |
4.78e-04 |
|
GHKL domain; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433996 [Multi-domain] Cd Length: 102 Bit Score: 39.12 E-value: 4.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 347 VLSNLISNA---VKYSEPNSVI--TIDIKNDWLCVTNMTHSEVNLKPLMDIKFDLNKEGSHGLGLYIIKTLLKNYGIEYA 421
Cdd:pfam14501 9 IFGNLLDNAieaCSKIDDNRFIrlKIREKQNFLIIRIENTYEGELKFEGKLPSTKTKGDGHGIGLKSIRRIVKKYGGNLS 88
|
90
....*....|....
gi 1328117890 422 VENTDRTFTFKIKL 435
Cdd:pfam14501 89 TEIENGIFTLSILL 102
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
1-218 |
4.98e-04 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 42.31 E-value: 4.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 1 MKKLKIFPKMFIQIFSVLVLFIMIIHLLVFFMFPKSYLETRKHELTVKANEIAEYLDGKDLNYITQSLEFFSSSNDIKAF 80
Cdd:COG0840 38 AALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLAALAALLALLE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 81 IKKGVNANELAIDEGIDVNLNSNTNSLIVEDRA---IHSSSGVELMINFVSTADMLKEAKSISFKFLPLSVIFSIAVSII 157
Cdd:COG0840 118 LLLAALLAALAIALLALAALLALAALALALLALallAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAII 197
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1328117890 158 IAFIYAKMIKHNIGEIKDVTDQMMQLDRQAYLKVNSADEIAELKLQINELYRSLLSSIDDI 218
Cdd:COG0840 198 LALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVGQV 258
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
343-425 |
5.12e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 39.37 E-value: 5.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 343 ALNLVLSNLISNAVKYSEPNSVITIDIKNDWLC----VTNMTH--SEVNLKPLMDIKF---DLNKEGSH-GLGLYIIKTL 412
Cdd:cd16975 4 LLSRALINIISNACQYAPEGGTVSISIYDEEEYlyfeIWDNGHgfSEQDLKKALELFYrddTSRRSGGHyGMGLYIAKNL 83
|
90
....*....|...
gi 1328117890 413 LKNYGIEYAVENT 425
Cdd:cd16975 84 VEKHGGSLIIENS 96
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
190-255 |
5.54e-04 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 41.93 E-value: 5.54e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1328117890 190 KVNSADEIAELKLQINELYRSLlssiddiEvKNkeiiklEQMKYDFLRGSSHELKTPLSRMKIILE 255
Cdd:PRK10549 212 TPTSRDELGRLAQDFNQLASTL-------E-KN------EQMRRDFMADISHELRTPLAVLRGELE 263
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
235-378 |
6.52e-04 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 41.94 E-value: 6.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 235 FLRGSSHELKTPLSRMKIILENMKYNIGKYKDRD---LYIDKCLDITNELtynISQILTFSSLEYLK--DDEEWVTIKSV 309
Cdd:PRK10337 240 FTSDAAHELRSPLAALKVQTEVAQLSDDDPQARKkalLQLHAGIDRATRL---VDQLLTLSRLDSLDnlQDVAEIPLEDL 316
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1328117890 310 LDAVLVKYDELA------MRNHLTFNSTIQSEQLLIgkkaLNLVLSNLISNAVKYSEPNSVITIDIKNDWLCVTN 378
Cdd:PRK10337 317 LQSAVMDIYHTAqqagidVRLTLNAHPVIRTGQPLL----LSLLVRNLLDNAIRYSPQGSVVDVTLNARNFTVRD 387
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
231-295 |
8.21e-04 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 37.55 E-value: 8.21e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1328117890 231 MKYDFLRGSSHELKTPLSRMKIILENMKYNIGKYKDRDL--YIDKCLDITNELtynISQILTFSSLE 295
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEEQREYleTILREAERLLRL---INDLLDLSRIE 64
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
231-295 |
1.33e-03 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 37.19 E-value: 1.33e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1328117890 231 MKYDFLRGSSHELKTPLSRMKIILENMKyNIGKYKDRDLYIDKCLDITNELTYNISQILTFSSLE 295
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLR-DEKLDEEQREYLETILRSAERLLRLINDLLDLSRIE 64
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
241-368 |
3.39e-03 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 39.44 E-value: 3.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328117890 241 HELKTPLSRMK----IILENMKYnigkyKDRDLYIDKCLDITNELTYNISQILTFSSLEYLK--DDEEWVTIKSVLDAVL 314
Cdd:PRK11100 265 HELKSPLAAIRgaaeLLQEDPPP-----EDRARFTGNILTQSARLQQLIDRLLELARLEQRQelEVLEPVALAALLEELV 339
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1328117890 315 VKYDELAMRNHLTF-----NSTIQSEQLLigkkaLNLVLSNLISNAVKYSEPNSVITID 368
Cdd:PRK11100 340 EAREAQAAAKGITLrlrpdDARVLGDPFL-----LRQALGNLLDNAIDFSPEGGTITLS 393
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
144-219 |
4.79e-03 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 39.17 E-value: 4.79e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1328117890 144 LPLSVIFSIAVSIIIAFIYAKMIKHNIGEIKDVTDQMMQLDRQAYLKVNSADEIAELKLQINELYRSLLSSIDDIE 219
Cdd:COG5000 11 LLLIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQREELE 86
|
|
|