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Conserved domains on  [gi|1330235446|ref|WP_102393805|]
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MULTISPECIES: tetratricopeptide repeat protein [unclassified Vibrio]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11434433)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
33-135 1.13e-18

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 78.82  E-value: 1.13e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330235446  33 AATMDQSQQHQDVVQLLDEAYQGQLEAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQAS 112
Cdd:COG0790    39 AALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQD 118

                          90       100
                  ....*....|....*....|...
gi 1330235446 113 QAEAVTWIGMAAAQEYDPALDLL 135
Cdd:COG0790   119 YAKALEWYEKAAEQGDADAQYNL 141
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
33-135 1.13e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 78.82  E-value: 1.13e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330235446  33 AATMDQSQQHQDVVQLLDEAYQGQLEAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQAS 112
Cdd:COG0790    39 AALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQD 118

                          90       100
                  ....*....|....*....|...
gi 1330235446 113 QAEAVTWIGMAAAQEYDPALDLL 135
Cdd:COG0790   119 YAKALEWYEKAAEQGDADAQYNL 141
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 58-91 8.18e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 40.20  E-value: 8.18e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1330235446  58 EAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNG 91
Cdd:pfam08238   2 EAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 58-92 6.19e-05

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 37.92  E-value: 6.19e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 1330235446   58 EAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNGS 92
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
33-135 1.13e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 78.82  E-value: 1.13e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330235446  33 AATMDQSQQHQDVVQLLDEAYQGQLEAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQAS 112
Cdd:COG0790    39 AALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQD 118

                          90       100
                  ....*....|....*....|...
gi 1330235446 113 QAEAVTWIGMAAAQEYDPALDLL 135
Cdd:COG0790   119 YAKALEWYEKAAEQGDADAQYNL 141
TPR COG0790
TPR repeat [General function prediction only];
52-138 1.77e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 78.43  E-value: 1.77e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330235446  52 AYQGQLEAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQASQAEAVTWIGMAAAQEYDPA 131
Cdd:COG0790    94 AEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADA 173


                  ....*..
gi 1330235446 132 LDLLHWM 138
Cdd:COG0790   174 QYNLGVL 180
TPR COG0790
TPR repeat [General function prediction only];
52-138 2.92e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 77.66  E-value: 2.92e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330235446  52 AYQGQLEAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQASQAEAVTWIGMAAAQEYDPA 131
Cdd:COG0790   130 AEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADA 209


                  ....*..
gi 1330235446 132 LDLLHWM 138
Cdd:COG0790   210 QYNLGRL 216
TPR COG0790
TPR repeat [General function prediction only];
52-126 9.65e-15

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 68.42  E-value: 9.65e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1330235446  52 AYQGQLEAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQASQAEAVTWIGMAAAQ 126
Cdd:COG0790   166 AEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
48-138 4.25e-06

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 44.53  E-value: 4.25e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330235446  48 LLDEAYQGQLEAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQASQAEAVTWIGMAAAQE 127
Cdd:COG0790    18 LAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQG 97

                          90
                  ....*....|.
gi 1330235446 128 YDPALDLLHWM 138
Cdd:COG0790    98 DAEAQYNLGLM 108
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 58-91 8.18e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 40.20  E-value: 8.18e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1330235446  58 EAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNG 91
Cdd:pfam08238   2 EAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 58-92 6.19e-05

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 37.92  E-value: 6.19e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 1330235446   58 EAQLSVAYLYLSGEGVEQDDEKAAEWFVTAANNGS 92
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 93-128 2.77e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 33.69  E-value: 2.77e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1330235446   93 PEAQTQLGLMYISGSGVQASQAEAVTWIGMAAAQEY 128
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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