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Conserved domains on  [gi|1332565888|ref|WP_102620700|]
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MULTISPECIES: type IV pilus biogenesis/stability protein PilW [unclassified Pseudomonas]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459648)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
193-254 2.81e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


:

Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 2.81e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1332565888 193 QNVQAYNDLGFYLAEGGKDELALKFYRGVEAVGKRTVLMLNIADSLWRLDRKDEAQRYYSQY 254
Cdd:COG3063    24 DNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERA 85
 
Name Accession Description Interval E-value
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
193-254 2.81e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 2.81e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1332565888 193 QNVQAYNDLGFYLAEGGKDELALKFYRGVEAVGKRTVLMLNIADSLWRLDRKDEAQRYYSQY 254
Cdd:COG3063    24 DNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERA 85
TPR_12 pfam13424
Tetratricopeptide repeat;
197-258 7.59e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 34.67  E-value: 7.59e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1332565888 197 AYNDLGFYLAEGGKDELALKFYRGVEAVGKRT---------VLMLNIADSLWRLDRKDEAQRYYSQYRDAM 258
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhpltaTTLLNLGRLYLELGRYEEALELLERALALA 75
 
Name Accession Description Interval E-value
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
193-254 2.81e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 2.81e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1332565888 193 QNVQAYNDLGFYLAEGGKDELALKFYRGVEAVGKRTVLMLNIADSLWRLDRKDEAQRYYSQY 254
Cdd:COG3063    24 DNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERA 85
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 194-256 5.88e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.56  E-value: 5.88e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1332565888 194 NVQAYNDLGFYLAEGGKDELALKFYR-GVEAVGKRTVLMLNIADSLWRLDRKDEAQRYYSQYRD 256
Cdd:COG5010    87 NPELYYNLALLYSRSGDKDEAKEYYEkALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 193-257 9.22e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.63  E-value: 9.22e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1332565888 193 QNVQAYNDLGFYLAEGGKDELALKFY-RGVEAVGKRTVLMLNIADSLWRLDRKDEAQRYYSQYRDA 257
Cdd:COG4783    36 DNPEAFALLGEILLQLGDLDEAIVLLhEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKL 101
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 193-261 1.70e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 1.70e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332565888 193 QNVQAYNDLGFYLAEGGKDELALKFY-RGVEAVGKRTVLMLNIADSLWRLDRKDEAQRYYSQYRDAMSAD 261
Cdd:COG4783    70 DEPEARLNLGLALLKAGDYDEALALLeKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
193-253 3.17e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.06  E-value: 3.17e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1332565888 193 QNVQAYNDLGFYLAEGGKDELALKFY-RGVEAVGKRTVLMLNIADSLWRLDRKDEAQRYYSQ 253
Cdd:COG0457    40 DDAEALYNLGLAYLRLGRYEEALADYeQALELDPDDAEALNNLGLALQALGRYEEALEDYDK 101
TPR_12 pfam13424
Tetratricopeptide repeat;
197-258 7.59e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 34.67  E-value: 7.59e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1332565888 197 AYNDLGFYLAEGGKDELALKFYRGVEAVGKRT---------VLMLNIADSLWRLDRKDEAQRYYSQYRDAM 258
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhpltaTTLLNLGRLYLELGRYEEALELLERALALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
194-253 7.59e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 36.91  E-value: 7.59e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1332565888 194 NVQAYNDLGFYLAEGGKDELALKFY-RGVEAVGKRTVLMLNIADSLWRLDRKDEAQRYYSQ 253
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYeKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQ 67
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
193-253 9.44e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 36.91  E-value: 9.44e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1332565888 193 QNVQAYNDLGFYLAEGGKDELALKFY-RGVEAVGKRTVLMLNIADSLWRLDRKDEAQRYYSQ 253
Cdd:COG0457    74 DDAEALNNLGLALQALGRYEEALEDYdKALELDPDDAEALYNLGLALLELGRYDEAIEAYER 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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