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Conserved domains on  [gi|1333913723|ref|WP_103015875|]
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RDD family protein [Salinibacter ruber]

Protein Classification

RDD family protein( domain architecture ID 872)

RDD (Arginine-Aspartate-Aspartate) family protein similar to Mycobacterium tuberculosis proline-rich antigen that belongs to the mycobacterial Pra family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RDD super family cl00746
RDD family; This family of proteins contain three highly conserved amino acids: one arginine ...
 16-151 2.51e-09

RDD family; This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).


The actual alignment was detected with superfamily member COG1714:

Pssm-ID: 469900  Cd Length: 143  Bit Score: 52.58  E-value: 2.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333913723  16 RFVAALLDGIIATGLTALFGGAPMLGGLVGGLYLVARDGFEVGPLRF---------RSPGKYVMGLDLVRLDGGPVSLET 86
Cdd:COG1714    21 RLLAFLIDLLILFALLLLLALVLLLGLLGALLGLLLLLGFLVAFLYFvlfetlrrgQTLGKRALGLRVVDLDGGPISFGQ 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1333913723  87 SVQRNWMlglssvagafivvpivggALASFLSLaGLGFILfeiynVFADPVGRRWGDRLGNTKVV 151
Cdd:COG1714   101 ALLRNLL------------------RILSILPL-GLGLLW-----ALFDKRRQRLHDLLAGTVVV 141
 
Name Accession Description Interval E-value
YckC COG1714
Uncharacterized membrane protein YckC, RDD family [Function unknown];
16-151 2.51e-09

Uncharacterized membrane protein YckC, RDD family [Function unknown];


Pssm-ID: 441320  Cd Length: 143  Bit Score: 52.58  E-value: 2.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333913723  16 RFVAALLDGIIATGLTALFGGAPMLGGLVGGLYLVARDGFEVGPLRF---------RSPGKYVMGLDLVRLDGGPVSLET 86
Cdd:COG1714    21 RLLAFLIDLLILFALLLLLALVLLLGLLGALLGLLLLLGFLVAFLYFvlfetlrrgQTLGKRALGLRVVDLDGGPISFGQ 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1333913723  87 SVQRNWMlglssvagafivvpivggALASFLSLaGLGFILfeiynVFADPVGRRWGDRLGNTKVV 151
Cdd:COG1714   101 ALLRNLL------------------RILSILPL-GLGLLW-----ALFDKRRQRLHDLLAGTVVV 141
RDD pfam06271
RDD family; This family of proteins contain three highly conserved amino acids: one arginine ...
 16-116 6.68e-04

RDD family; This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).


Pssm-ID: 428859  Cd Length: 134  Bit Score: 37.70  E-value: 6.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333913723  16 RFVAALLDGIIATGLTALFGGAPMLGGLVGGLYLVARDGFEVGPL---------------RFRSPGKYVMGLDLVRLDGG 80
Cdd:pfam06271   6 RLLAFLIDLLILLIISLLLALLFGLIGFSPGLATAGSLLLLLLLVfllvllvyfllfeskTGQTLGKRLLGIRVVDADGR 85

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1333913723  81 PVSLETSVQRNWMLGLSSVAGAFIVVPIVGGALASF 116
Cdd:pfam06271  86 PLSLAQALIRALLLLLPVLGLVGFLLFLIGFLFLLF 121
 
Name Accession Description Interval E-value
YckC COG1714
Uncharacterized membrane protein YckC, RDD family [Function unknown];
16-151 2.51e-09

Uncharacterized membrane protein YckC, RDD family [Function unknown];


Pssm-ID: 441320  Cd Length: 143  Bit Score: 52.58  E-value: 2.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333913723  16 RFVAALLDGIIATGLTALFGGAPMLGGLVGGLYLVARDGFEVGPLRF---------RSPGKYVMGLDLVRLDGGPVSLET 86
Cdd:COG1714    21 RLLAFLIDLLILFALLLLLALVLLLGLLGALLGLLLLLGFLVAFLYFvlfetlrrgQTLGKRALGLRVVDLDGGPISFGQ 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1333913723  87 SVQRNWMlglssvagafivvpivggALASFLSLaGLGFILfeiynVFADPVGRRWGDRLGNTKVV 151
Cdd:COG1714   101 ALLRNLL------------------RILSILPL-GLGLLW-----ALFDKRRQRLHDLLAGTVVV 141
RDD pfam06271
RDD family; This family of proteins contain three highly conserved amino acids: one arginine ...
 16-116 6.68e-04

RDD family; This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).


Pssm-ID: 428859  Cd Length: 134  Bit Score: 37.70  E-value: 6.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333913723  16 RFVAALLDGIIATGLTALFGGAPMLGGLVGGLYLVARDGFEVGPL---------------RFRSPGKYVMGLDLVRLDGG 80
Cdd:pfam06271   6 RLLAFLIDLLILLIISLLLALLFGLIGFSPGLATAGSLLLLLLLVfllvllvyfllfeskTGQTLGKRLLGIRVVDADGR 85

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1333913723  81 PVSLETSVQRNWMLGLSSVAGAFIVVPIVGGALASF 116
Cdd:pfam06271  86 PLSLAQALIRALLLLLPVLGLVGFLLFLIGFLFLLF 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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