|
Name |
Accession |
Description |
Interval |
E-value |
| GT4_CapM-like |
cd03808 |
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ... |
93-363 |
1.18e-54 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.
Pssm-ID: 340837 [Multi-domain] Cd Length: 358 Bit Score: 183.95 E-value: 1.18e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 93 PDVIHAHSAKAGLAGRLAVR--GRIPTVFQPHAWSFEALEG-RAAGLAEAWERFGARWSDRILCVSESERHAGQRAGIAA 169
Cdd:cd03808 82 PDIVHCHTPKPGILGRLAARlaGVPKVIYTVHGLGFVFTEGkLLRLLYLLLEKLALLFTDKVIFVNEDDRDLAIKKGIIK 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 170 RWSVI---HNGVDLGRFRPAPGDAmrsaraslplladvPPGAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLVLVG 244
Cdd:cd03808 162 KKKTVlipGSGVDLDRFQYSPESL--------------PSEKVVFLFVARLLKDKGIDELIEAAKILkkKGPNVRFLLVG 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 245 EGPRGGEL-----RRGAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGhL 319
Cdd:cd03808 228 DGELENPSeilieKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELVIDG-V 306
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1338278072 320 PHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDL 363
Cdd:cd03808 307 NGFLVPPGDVEALADAIEKLIEDPELRKEMGEAARKRVEEKFDE 350
|
|
| GT4_PimA-like |
cd03801 |
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
14-375 |
6.60e-54 |
|
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 182.35 E-value: 6.60e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 14 VLHLVQ---PVEGGVARVVTDLVAAQVRAGLRPVVACPPGGGLAEGAAEAGARVWAWPAERVPgPRLAREVAAAGRLVRV 90
Cdd:cd03801 2 ILLLSPelpPPVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAAL-LRARRLLRELRPLLRL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 91 CAPDVIHAHSAKAGLAGRLAVRG-RIPTVFQPHAWSFEALEGRAAG----LAEAWERFgaRWSDRILCVSESERHAGQRA 165
Cdd:cd03801 81 RKFDVVHAHGLLAALLAALLALLlGAPLVVTLHGAEPGRLLLLLAAerrlLARAEALL--RRADAVIAVSEALRDELRAL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 166 GIA--ARWSVIHNGVDLGRFRPApgdamrsARASLPLladvPPGAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLV 241
Cdd:cd03801 159 GGIppEKIVVIPNGVDLERFSPP-------LRRKLGI----PPDRPVLLFVGRLSPRKGVDLLLEALAKLlrRGPDVRLV 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 242 LVG-EGPRGGELRR---GAPDGVLFAGA--ARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLP 315
Cdd:cd03801 228 IVGgDGPLRAELEElelGLGDRVRFLGFvpDEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLPEVVE 307
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 316 PGHLpHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLYQ 375
Cdd:cd03801 308 DGEG-GLVVPPDDVEALADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLYR 366
|
|
| GT4_WbnK-like |
cd03807 |
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ... |
86-374 |
1.13e-40 |
|
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.
Pssm-ID: 340836 [Multi-domain] Cd Length: 362 Bit Score: 147.46 E-value: 1.13e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 86 RLVRVCAPDVIHAHSAKAGLAGRLAVRG-RIPTVFqphaWSFE--ALEGRAAGLAEAWERFGARWSDRILCVSESERHAG 162
Cdd:cd03807 73 KLIRKRNPDVVHTWMYHADLIGGLAAKLaGGVKVI----WSVRssNIPQRLTRLVRKLCLLLSKFSPATVANSSAVAEFH 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 163 QRAGIAARWS-VIHNGVDLGRFRPAPGDAmRSARASLPLLADVPpgapLAVCVGRLSRQKGQDVLLSAWRRV--RVPGAR 239
Cdd:cd03807 149 QEQGYAKNKIvVIYNGIDLFKLSPDDASR-ARARRRLGLAEDRR----VIGIVGRLHPVKDHSDLLRAAALLveTHPDLR 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 240 LVLVGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESL 314
Cdd:cd03807 224 LLLVGRGPERPNLERlllelGLEDRVHLLGERSDVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVGGAAELV 303
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 315 PPGhlPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLY 374
Cdd:cd03807 304 DDG--TGFLVPAGDPQALADAIRALLEDPEKRARLGRAARERIANEFSIDAMVRRYETLY 361
|
|
| GT4_GT28_WabH-like |
cd03811 |
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ... |
23-362 |
1.91e-40 |
|
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.
Pssm-ID: 340839 [Multi-domain] Cd Length: 351 Bit Score: 146.35 E-value: 1.91e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 23 GGVARVVTDLVAAQVRAGLRP--VVACPPGGGLAEGAAEAGARVWAWPAERVPGPRLAREVAAAGRLVRVCAPDVIHAHS 100
Cdd:cd03811 12 GGAERVLLNLANALDKRGYDVtlVLLRDEGDLDKQLNGDVKLIRLLIRVLKLIKLGLLKAILKLKRILKRAKPDVVISFL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 101 AKAGLAGRLAVRGRIPTVFQPHAWSFEALEGRAAGLaeaWERFGARWSDRILCVSESERHAGQRAGI--AARWSVIHNGV 178
Cdd:cd03811 92 GFATYIVAKLAAARSKVIAWIHSSLSKLYYLKKKLL---LKLKLYKKADKIVCVSKGIKEDLIRLGPspPEKIEVIYNPI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 179 DLGRFRpapgdamrsARASLPLLADvPPGAPLAVCVGRLSRQKGQDVLLSAWRRVR--VPGARLVLVGEGPRGGELRR-- 254
Cdd:cd03811 169 DIDRIR---------ALAKEPILNE-PEDGPVILAVGRLDPQKGHDLLIEAFAKLRkkYPDVKLVILGDGPLREELEKla 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 255 ---GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHlpHCLVPPEDPAA 331
Cdd:cd03811 239 kelGLAERVIFLGFQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPGPREILDDGE--NGLLVPDGDAA 316
|
330 340 350
....*....|....*....|....*....|.
gi 1338278072 332 LASALTALLGDAGLRAELGSAAGAHARSVFD 362
Cdd:cd03811 317 ALAGILAALLQKKLDAALRERLAKAQEAVFR 347
|
|
| GT4_WavL-like |
cd03819 |
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ... |
19-365 |
2.69e-36 |
|
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.
Pssm-ID: 340846 [Multi-domain] Cd Length: 345 Bit Score: 135.18 E-value: 2.69e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 19 QPVEGGVARVVTDLVAAQVRAGLRPVVACPpgggLAEGAAEAGARVWAWPAERVPGPRLAREVAAAGRLVRVCAPDVIHA 98
Cdd:cd03819 7 ALEIGGAETYILDLARALAERGHRVLVVTA----GGPLLPRLRQIGIGLPGLKVPLLRALLGNVRLARLIRRERIDLIHA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 99 HSAKAGLAGRLAVRG-RIPTVFQPHawSFEALEGRAAGLAEAWERFGarwsDRILCVSESERHAGQRAG--IAARWSVIH 175
Cdd:cd03819 83 HSRAPAWLGWLASRLtGVPLVTTVH--GSYLATYHPKDFALAVRARG----DRVIAVSELVRDHLIEALgvDPERIRVIP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 176 NGVDLGRFRPAPGDAMRSAraslpllADVPPGAPLAVCVGRLSRQKGQDVLLSAWRRV-RVPGARLVLVGEGPRGGELRR 254
Cdd:cd03819 157 NGVDTDRFPPEAEAEERAQ-------LGLPEGKPVVGYVGRLSPEKGWLLLVDAAAELkDEPDFRLLVAGDGPERDEIRR 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 255 -----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGhLPHCLVPPEDP 329
Cdd:cd03819 230 lverlGLRDRVTFTGFREDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGAREIVVHG-RTGLLVPPGDA 308
|
330 340 350
....*....|....*....|....*....|....*.
gi 1338278072 330 AALASALTALLGDAGLRAELGSAAGAHARSVFDLTR 365
Cdd:cd03819 309 EALADAIRAAKLLPEAREKLQAAAALTEAVRELLLR 344
|
|
| GT4-like |
cd03814 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
20-358 |
1.81e-34 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340842 [Multi-domain] Cd Length: 365 Bit Score: 130.88 E-value: 1.81e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 20 PVEGGVARVVTDLVAAQVRAGLRPVVACPPGGGLAEGAAEAGARVWAWPAERVPGPRLAreVAAAGRLVRVC---APDVI 96
Cdd:cd03814 11 PQVNGVVRTLERLVDHLRRRGHEVRVVAPGPFDEAESAEGRVVSVPSFPLPFYPEYRLA--LPLPRRVRRLIkefQPDII 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 97 HAHS-AKAGLAGR-LAVRGRIPTVFQPHAWSFEALEGRAAGLAEAWERFGARW----SDRILCVSESERHAGQRAGI--A 168
Cdd:cd03814 89 HIATpGPLGLAALrAARRLGLPVVTSYHTDFPEYLSYYTLGPLSWLAWAYLRWfhnpFDTTLVPSPSIARELEGHGFerV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 169 ARWSvihNGVDLGRFRPAPGD-AMRSARAslplladvPPGAPLAVCVGRLSRQKGQDVLLSAWRR-VRVPGARLVLVGEG 246
Cdd:cd03814 169 RLWP---RGVDTELFHPSRRDaALRRRLG--------PPGRPLLLYVGRLAPEKNLEALLDADLPlAASPPVRLVVVGDG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 247 PRGGELRRGAPDgVLFAGAA-RDVRPWIHA-ADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLPhCLV 324
Cdd:cd03814 238 PARAELEARGPD-VIFTGFLtGEELARAYAsADVFVFPSRTETFGLVVLEAMASGLPVVAADAGGPRDIVRPGGTG-ALV 315
|
330 340 350
....*....|....*....|....*....|....
gi 1338278072 325 PPEDPAALASALTALLGDAGLRAELGSAAGAHAR 358
Cdd:cd03814 316 EPGDAAAFAAALRALLEDPELRRRMAARARAEAE 349
|
|
| Glyco_trans_1_4 |
pfam13692 |
Glycosyl transferases group 1; |
208-329 |
1.42e-31 |
|
Glycosyl transferases group 1;
Pssm-ID: 463957 [Multi-domain] Cd Length: 138 Bit Score: 116.46 E-value: 1.42e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 208 APLAVCVGRLS-RQKGQDVLLSAWRRVR--VPGARLVLVGEGPRGG--ELRRGAPDGVLFAGAARDVRPWIHAADVLVLP 282
Cdd:pfam13692 1 RPVILFVGRLHpNVKGVDYLLEAVPLLRkrDNDVRLVIVGDGPEEEleELAAGLEDRVIFTGFVEDLAELLAAADVFVLP 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1338278072 283 SRWEGMALAPLEAMACGRPVLLSDVNGARESLPpgHLPHCLVPPEDP 329
Cdd:pfam13692 81 SLYEGFGLKLLEAMAAGLPVVATDVGGIPELVD--GENGLLVPPGDP 125
|
|
| GT4_sucrose_synthase |
cd03800 |
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ... |
93-361 |
3.12e-30 |
|
sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.
Pssm-ID: 340830 [Multi-domain] Cd Length: 398 Bit Score: 119.65 E-value: 3.12e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 93 PDVIHAHSAKAGLAG-RLAVRGRIPTVFQPHA------------WSFEALEGRAAglaeawERFGARWSDRILcVSESER 159
Cdd:cd03800 102 YDLIHSHYWDSGLVGaLLARRLGVPLVHTFHSlgrvkyrhlgaqDTYHPSLRITA------EEQILEAADRVI-ASTPQE 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 160 HAGQRAGIAA---RWSVIHNGVDLGRFRPAPGDAMRSARASLPlladvpPGAPLAVCVGRLSRQKGQDVLLSAW--RRVR 234
Cdd:cd03800 175 ADELISLYGAdpsRINVVPPGVDLERFFPVDRAEARRARLLLP------PDKPVVLALGRLDPRKGIDTLVRAFaqLPEL 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 235 VPGARLVLVGeGPRGGELRRGAP------------DGVLFAGAAR--DVRPWIHAADVLVLPSRWEGMALAPLEAMACGR 300
Cdd:cd03800 249 RELANLVLVG-GPSDDPLSMDREelaelaeelgliDRVRFPGRVSrdDLPELYRAADVFVVPSLYEPFGLTAIEAMACGT 327
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338278072 301 PVLLSDVNGARESLPPGHlPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVF 361
Cdd:cd03800 328 PVVATAVGGLQDIVRDGR-TGLLVDPHDPEALAAALRRLLDDPALWQRLSRAGLERARAHY 387
|
|
| GT4_WlbH-like |
cd03798 |
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ... |
93-329 |
1.57e-29 |
|
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
Pssm-ID: 340828 [Multi-domain] Cd Length: 376 Bit Score: 117.48 E-value: 1.57e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 93 PDVIHAHSAKAGLAGRLAVRGRIPTVFQPHAWSFEALEGRAAGLAEAWERFGARWSDRILCVSESERHAGQRAGIAA-RW 171
Cdd:cd03798 96 PDLIHAHFAYPAGFAAALLARLYGVPYVVTEHGSDINVFPPRSLLRKLLRWALRRAARVIAVSKALAEELVALGVPRdRV 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 172 SVIHNGVDLGRFRPAPgdamrsaraslpLLADVPPGAPLAVCVGRLSRQKGQDVLLSA--WRRVRVPGARLVLVGEGPRG 249
Cdd:cd03798 176 DVIPNGVDPARFQPED------------RGLGLPLDAFVILFVGRLIPRKGIDLLLEAfaRLAKARPDVVLLIVGDGPLR 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 250 GELRRGAP-----DGVLFAGA--ARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHlPHC 322
Cdd:cd03798 244 EALRALAEdlglgDRVTFTGRlpHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVGGIPEVVGDPE-TGL 322
|
....*..
gi 1338278072 323 LVPPEDP 329
Cdd:cd03798 323 LVPPGDA 329
|
|
| Glycos_transf_1 |
pfam00534 |
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ... |
209-329 |
6.67e-27 |
|
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
Pssm-ID: 425737 [Multi-domain] Cd Length: 158 Bit Score: 104.66 E-value: 6.67e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 209 PLAVCVGRLSRQKGQDVLLSAWRRVR--VPGARLVLVGEGPRGGELR-----RGAPDGVLFAGAARDVRPW--IHAADVL 279
Cdd:pfam00534 3 KIILFVGRLEPEKGLDLLIKAFALLKekNPNLKLVIAGDGEEEKRLKklaekLGLGDNVIFLGFVSDEDLPelLKIADVF 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 1338278072 280 VLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHlPHCLVPPEDP 329
Cdd:pfam00534 83 VLPSRYEGFGIVLLEAMACGLPVIASDVGGPPEVVKDGE-TGFLVKPNNA 131
|
|
| GT4_UGDG-like |
cd03817 |
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ... |
71-377 |
5.54e-26 |
|
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Pssm-ID: 340844 [Multi-domain] Cd Length: 372 Bit Score: 107.36 E-value: 5.54e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 71 RVPGPRLAREvaAAGRLVRVCAPDVIHAHSA-KAGLAG-RLAVRGRIPTV----FQPHAWSFEALEGRAaglaeaWERFG 144
Cdd:cd03817 65 RQHIPFPFKK--AVIDRIKELGPDIIHTHTPfSLGKLGlRIARKLKIPIVhtyhTMYEDYLHYIPKGKL------LVKAV 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 145 ARW--------SDRILCVSESERHAGQRAGIAARWSVIHNGVDLGRFRPAPGDAmrsARASLPLladvPPGAPLAVCVGR 216
Cdd:cd03817 137 VRKlvrrfynhTDAVIAPSEKIKDTLREYGVKGPIEVIPNGIDLDKFEKPLNTE---ERRKLGL----PPDEPILLYVGR 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 217 LSRQKGQDVLLSAWRRVR-VPGARLVLVGEGPRGGELRR-----GAPDGVLFAGaardVRPW------IHAADVLVLPSR 284
Cdd:cd03817 210 LAKEKNIDFLLRAFAELKkEPNIKLVIVGDGPEREELKElarelGLADKVIFTG----FVPReelpeyYKAADLFVFAST 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 285 WEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLpHCLVPPEDPAALASALTALLGDAgLRAELGSAAGAHARSvFDLT 364
Cdd:cd03817 286 TETQGLVYLEAMAAGLPVVAAKDPAASELVEDGEN-GFLFEPNDETLAEKLLHLRENLE-LLRKLSKNAEISARE-FAFA 362
|
330
....*....|...
gi 1338278072 365 RtsgAVLRLYQEL 377
Cdd:cd03817 363 K---SVEKLYEEV 372
|
|
| GT4-like |
cd05844 |
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ... |
71-369 |
1.81e-25 |
|
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340860 [Multi-domain] Cd Length: 365 Bit Score: 106.00 E-value: 1.81e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 71 RVPGPRLAREVAAAGRLVRVCAPDVIHAHSAKAG-LAGRLAVRGRIPTVFQPHAWSFEALEGRAAGLAEAWERFGARW-- 147
Cdd:cd05844 60 RQMAQRLLGWSAPRLGGAAGLAPALVHAHFGRDGvYALPLARALGVPLVVTFHGFDITTSRAWLAASPGWPSQFQRHRra 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 148 ----SDRILCVSESERHAGQRAGIAA-RWSVIHNGVDLGRFRPAPgdamrsaraslplladVPPGAPLAVCVGRLSRQKG 222
Cdd:cd05844 140 lqrpAALFVAVSGFIRDRLLARGLPAeRIHVHYIGIDPAKFAPRD----------------PAERAPTILFVGRLVEKKG 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 223 QDVLLSAWRRV--RVPGARLVLVGEGPRGGELRRGAPDG--VLFAGA--ARDVRPWIHAADVLVLPSRW------EGMAL 290
Cdd:cd05844 204 CDVLIEAFRRLaaRHPTARLVIAGDGPLRPALQALAAALgrVRFLGAlpHAEVQDWMRRAEIFCLPSVTaasgdsEGLGI 283
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338278072 291 APLEAMACGRPVLLSDVNGARESLPPGHlPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGA 369
Cdd:cd05844 284 VLLEAAACGVPVVSSRHGGIPEAILDGE-TGFLVPEGDVDALADALQALLADRALADRMGGAARAFVCEQFDIRVQTAK 361
|
|
| GT4_AmsD-like |
cd03820 |
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ... |
86-306 |
1.29e-23 |
|
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.
Pssm-ID: 340847 [Multi-domain] Cd Length: 351 Bit Score: 100.39 E-value: 1.29e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 86 RLVRVCAPDVI--HAHSAKAGLAGRLAvrgRIPTVFQPHawsFEALEGRAAGLAEAWERFGARWSDRILCVSESERHAGQ 163
Cdd:cd03820 81 KYLKNNKPDVVisFRTSLLTFLALIGL---KSKLIVWEH---NNYEAYNKGLRRLLLRRLLYKRADKIVVLTEADKLKKY 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 164 RaGIAARWSVIHNGVDLGRFRPAPgdamrsaraslplladvPPGAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLV 241
Cdd:cd03820 155 K-QPNSNVVVIPNPLSFPSEEPST-----------------NLKSKRILAVGRLTYQKGFDLLIEAWALIakKHPDWKLR 216
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 242 LVGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSD 306
Cdd:cd03820 217 IYGDGPEREELEKlidklGLEDRVKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFD 286
|
|
| GT4_BshA-like |
cd04962 |
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ... |
94-377 |
2.29e-23 |
|
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340859 [Multi-domain] Cd Length: 370 Bit Score: 100.12 E-value: 2.29e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 94 DVIHAH----SAKAGLAGRLAVRGRIPTVFQPHAWSFeALEGRAAGLAEAwERFGARWSDRILCVSESER-----HAGQR 164
Cdd:cd04962 86 DVLHAHyaipHASCAYLAREILGEKIPIVTTLHGTDI-TLVGYDPSLQPA-VRFSINKSDRVTAVSSSLRqetyeLFDVD 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 165 AGIaarwSVIHNGVDLGRFRPAPGDAMRSARAslplladVPPGAPLAVCVGRLSRQKGQDVLLSAWRRVR--VPgARLVL 242
Cdd:cd04962 164 KDI----EVIHNFIDEDVFKRKPAGALKRRLL-------APPDEKVVIHVSNFRPVKRIDDVVRVFARVRrkIP-AKLLL 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 243 VGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPG 317
Cdd:cd04962 232 VGDGPERVPAEElarelGVEDRVLFLGKQDDVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGGIPEVVKHG 311
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 318 hLPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLYQEL 377
Cdd:cd04962 312 -ETGFLSDVGDVDAMAKSALSILEDDELYNRMGRAARKRAAERFDPERIVPQYEAYYRRL 370
|
|
| stp2 |
TIGR03088 |
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ... |
168-378 |
2.85e-23 |
|
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.
Pssm-ID: 132132 [Multi-domain] Cd Length: 374 Bit Score: 99.80 E-value: 2.85e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 168 AARWSVIHNGVDLGRFRPAPGDamRSARASLPLLADVPPgapLAVCVGRLSRQKGQDVLLSAW------RRVRVPGARLV 241
Cdd:TIGR03088 159 PAKIHQIYNGVDTERFHPSRGD--RSPILPPDFFADESV---VVGTVGRLQAVKDQPTLVRAFallvrqLPEGAERLRLV 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 242 LVGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPP 316
Cdd:TIGR03088 234 IVGDGPARGACEQmvraaGLAHLVWLPGERDDVPALMQALDLFVLPSLAEGISNTILEAMASGLPVIATAVGGNPELVQH 313
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338278072 317 GhLPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLYQELV 378
Cdd:TIGR03088 314 G-VTGALVPPGDAVALARALQPYVSDPAARRAHGAAGRARAEQQFSINAMVAAYAGLYDQLL 374
|
|
| GT4_WbuB-like |
cd03794 |
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ... |
13-353 |
4.33e-22 |
|
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
Pssm-ID: 340825 [Multi-domain] Cd Length: 391 Bit Score: 96.64 E-value: 4.33e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 13 TVLHLVQ---PVEGGVARVVTDLVAAQVRAGLRPVVACPPGGGLAEGAAEAGA---------RVWAWPAERV-PGPRLAR 79
Cdd:cd03794 1 KILLISQyypPPKGAAAARVYELAKELVRRGHEVTVLTPSPNYPLGRIFAGATetkdgirviRVKLGPIKKNgLIRRLLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 80 EV-----AAAGRLVRVCAPDVIHAHSA---KAGLAGRLAVRGRIPTVFQPHAW---SFEALEGRAAGLAEAW----ERFG 144
Cdd:cd03794 81 YLsfalaALLKLLVREERPDVIIAYSPpitLGLAALLLKKLRGAPFILDVRDLwpeSLIALGVLKKGSLLKLlkklERKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 145 ARWSDRILCVSES-ERHAGQRAGIAARWSVIHNGVDLGRFRPAPGDAMRSARaslplladvPPGAPL-AVCVGRLSRQKG 222
Cdd:cd03794 161 YRLADAIIVLSPGlKEYLLRKGVPKEKIIVIPNWADLEEFKPPPKDELRKKL---------GLDDKFvVVYAGNIGKAQG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 223 QDVLLSAWRRVR-VPGARLVLVGEGPRGGELRRGA----PDGVLFAGA--ARDVRPWIHAADVLVL------------PS 283
Cdd:cd03794 232 LETLLEAAERLKrRPDIRFLFVGDGDEKERLKELAkargLDNVTFLGRvpKEEVPELLSAADVGLVplkdnpanrgssPS 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338278072 284 RWegmalapLEAMACGRPVLLSDVNGARESL---PPGhlphCLVPPEDPAALASALTALLGDAGLRAELGSAA 353
Cdd:cd03794 312 KL-------FEYMAAGKPILASDDGGSDLAVeinGCG----LVVEPGDPEALADAILELLDDPELRRAMGENG 373
|
|
| GT4_MtfB-like |
cd03809 |
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ... |
23-307 |
1.52e-21 |
|
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Pssm-ID: 340838 [Multi-domain] Cd Length: 362 Bit Score: 94.74 E-value: 1.52e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 23 GGVARVVTDLVAA-QVRAGLRPVVACPPGGGLAEGAAEAGARVWAWPAERVPGPRLAREVAAAGRLVRVCAPDVIHAHSa 101
Cdd:cd03809 14 TGIGRYTRELLKAlAKNDPDESVLAVPPLPGELLRLLREYPELSLGVIKIKLWRELALLRWLQILLPKKDKPDLLHSPH- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 102 kaGLAGRLavRGRIPTVFQPH-AWSFEALEGRAAGLAEAWERF---GARWSDRILCVSESERHAGQR-AGIAARW-SVIH 175
Cdd:cd03809 93 --NTAPLL--LKGCPQVVTIHdLIPLRYPEFFPKRFRLYYRLLlpiSLRRADAIITVSEATRDDIIKfYGVPPEKiVVIP 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 176 NGVDLgRFRPAPGDAMRSARASLPlladvppgAPLAVCVGRLSRQKGQDVLLSAWRRVR--VPGARLVLVG------EGP 247
Cdd:cd03809 169 LGVDP-SFFPPESAAVLIAKYLLP--------EPYFLYVGTLEPRKNHERLLKAFALLKkqGGDLKLVIVGgkgwedEEL 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338278072 248 RGGELRRGAPDGVLFAG--AARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDV 307
Cdd:cd03809 240 LDLVKKLGLGGRVRFLGyvSDEDLPALYRGARAFVFPSLYEGFGLPVLEAMACGTPVIASNI 301
|
|
| GT4_Bme6-like |
cd03821 |
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ... |
12-306 |
1.60e-21 |
|
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.
Pssm-ID: 340848 [Multi-domain] Cd Length: 377 Bit Score: 94.74 E-value: 1.60e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 12 LTVLHLVQPVEGGVARVVTDLVAAQVRAGLRPVVAC---PPGGGLAEGAAEAGARVWAWPAERVPGPRLAREVAAAGRLV 88
Cdd:cd03821 3 LHVTPSISPKAGGPVKVVLRLAAALAALGHEVTIVStgdGYESLVVEENGRYIPPQDGFASIPLLRQGAGRTDFSPGLPN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 89 RVCA----PDVIHAH---SAKAGLAGRLAVRGRIPTVFQPHAwsfeALEGRAAGLAE-----AWERFGARWSDRILCV-- 154
Cdd:cd03821 83 WLRRnlreYDVVHIHgvwTYTSLAACKLARRRGIPYVVSPHG----MLDPWALQQKHwkkriALHLIERRNLNNAALVhf 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 155 -SESERHAGQRAGIAARWSVIHNGVDLGRFRPAPGDAMRSAraslplladVPPGAPLAVCVGRLSRQKGQDVLLSAWRRV 233
Cdd:cd03821 159 tSEQEADELRRFGLEPPIAVIPNGVDIPEFDPGLRDRRKHN---------GLEDRRIILFLGRIHPKKGLDLLIRAARKL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 234 --RVPGARLVLVGEGPRGGELRR------GAPDGVLFAGAARDVRPWI--HAADVLVLPSRWEGMALAPLEAMACGRPVL 303
Cdd:cd03821 230 aeQGRDWHLVIAGPDDGAYPAFLqlqsslGLGDRVTFTGPLYGEAKWAlyASADLFVLPSYSENFGNVVAEALACGLPVV 309
|
...
gi 1338278072 304 LSD 306
Cdd:cd03821 310 ITD 312
|
|
| GT4_CapH-like |
cd03812 |
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ... |
146-307 |
5.64e-20 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).
Pssm-ID: 340840 [Multi-domain] Cd Length: 357 Bit Score: 90.04 E-value: 5.64e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 146 RWSDRILCVSEserhagqragIAARW----------SVIHNGVDLGRFrpAPGDAMRSARASLPLLADvppgaPLAVC-V 214
Cdd:cd03812 135 RLSTKYLACSE----------DAGEWlfgevengkfKVIPNGIDIEKY--KFNKEKRRKRRKLLILED-----KLVLGhV 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 215 GRLSRQKGQDVLLS--AWRRVRVPGARLVLVGEGPRGGELR-----RGAPDGVLFAGAARDVRPWIHAADVLVLPSRWEG 287
Cdd:cd03812 198 GRFNEQKNHSFLIDifEELKKKNPNVKLVLVGEGELKEKIKekvkeLGLEDKVIFLGFRNDVSEILSAMDVFLFPSLYEG 277
|
170 180
....*....|....*....|
gi 1338278072 288 MALAPLEAMACGRPVLLSDV 307
Cdd:cd03812 278 LPLVAVEAQASGLPCLLSDT 297
|
|
| Glyco_transf_4 |
pfam13439 |
Glycosyltransferase Family 4; |
23-180 |
1.05e-19 |
|
Glycosyltransferase Family 4;
Pssm-ID: 463877 [Multi-domain] Cd Length: 169 Bit Score: 85.28 E-value: 1.05e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 23 GGVARVVTDLVAAQVRAGLRPVVACPPGGGLAEGAAEAGARVWAWPAERVPGPRLA-REVAAAGRLVRVCAPDVIHAHSA 101
Cdd:pfam13439 1 GGVERYVLELARALARRGHEVTVVTPGGPGPLAEEVVRVVRVPRVPLPLPPRLLRSlAFLRRLRRLLRRERPDVVHAHSP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 102 KAGLAGRLAVR--GRIPTVFQPHA-----WSFEALEGRAAGLAEAWERFGARWSDRILCVSESER-HAGQRAGI-AARWS 172
Cdd:pfam13439 81 FPLGLAALAARlrLGIPLVVTYHGlfpdyKRLGARLSPLRRLLRRLERRLLRRADRVIAVSEAVAdELRRLYGVpPEKIR 160
|
....*...
gi 1338278072 173 VIHNGVDL 180
Cdd:pfam13439 161 VIPNGVDL 168
|
|
| GT4_WbdM_like |
cd04951 |
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ... |
174-329 |
1.52e-19 |
|
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340857 [Multi-domain] Cd Length: 360 Bit Score: 89.04 E-value: 1.52e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 174 IHNGVDLGRFRPAPgDAMRSARASLPLLADvppgAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLVLVGEGPRGGE 251
Cdd:cd04951 159 VYNGIDLNKFKKDI-NVRLKIRNKLNLKND----EFVILNVGRLTEAKDYPNLLLAISELilSKNDFKLLIAGDGPLRNE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 252 LRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLphcLVPP 326
Cdd:cd04951 234 LERlicnlNLVDRVILLGQISNISEYYNAADLFVLSSEWEGFGLVVAEAMACERPVVATDAGGVAEVVGDHNY---VVPV 310
|
...
gi 1338278072 327 EDP 329
Cdd:cd04951 311 SDP 313
|
|
| RfaB |
COG0438 |
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
272-379 |
1.02e-18 |
|
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 81.19 E-value: 1.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 272 WIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLPhCLVPPEDPAALASALTALLGDAGLRAELGS 351
Cdd:COG0438 17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETG-LLVPPGDPEALAEAILRLLEDPELRRRLGE 95
|
90 100
....*....|....*....|....*...
gi 1338278072 352 AAGAHARSVFDLTRTSGAVLRLYQELVG 379
Cdd:COG0438 96 AARERAEERFSWEAIAERLLALYEELLA 123
|
|
| Glyco_trans_4_4 |
pfam13579 |
Glycosyl transferase 4-like domain; |
23-177 |
3.23e-18 |
|
Glycosyl transferase 4-like domain;
Pssm-ID: 433325 [Multi-domain] Cd Length: 158 Bit Score: 80.91 E-value: 3.23e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 23 GGVARVVTDLVAAQVRAGLRPVVACPPGGGLAEGAAEAGARVWAWPAERVPGPRLA-REVAAAGRLVRVCAPDVIHAHSA 101
Cdd:pfam13579 1 GGIGVYVLELARALAALGHEVRVVTPGGPPGRPELVGDGVRVHRLPVPPRPSPLADlAALRRLRRLLRAERPDVVHAHSP 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338278072 102 KAGLAGRLA-VRGRIPTVFQPHAWSFEALEGRAAGLAEAWERFGARWSDRILCVSESERHAGQRAGI-AARWSVIHNG 177
Cdd:pfam13579 81 TAGLAARLArRRRGVPLVVTVHGLALDYGSGWKRRLARALERRLLRRADAVVVVSEAEAELLRALGVpAARVVVVPNG 158
|
|
| Glycosyltransferase_GTB-type |
cd01635 |
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
211-318 |
1.03e-17 |
|
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340816 [Multi-domain] Cd Length: 235 Bit Score: 81.68 E-value: 1.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 211 AVCVGRLSRQKGQDVLLSAWRRV--RVPGARLVLVGEGPRG-------GELRRGAPDGVLFAGAARDVRPWIHA-ADVLV 280
Cdd:cd01635 113 KVSVGRLVPEKGIDLLLEALALLkaRLPDLVLVLVGGGGEReeeealaAALGLLERVVIIGGLVDDEVLELLLAaADVFV 192
|
90 100 110
....*....|....*....|....*....|....*...
gi 1338278072 281 LPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGH 318
Cdd:cd01635 193 LPSRSEGFGLVLLEAMAAGKPVIATDVGGIPEFVVDGE 230
|
|
| MSMEG_0565_glyc |
TIGR04047 |
glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from ... |
94-376 |
4.11e-17 |
|
glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from Actinobacteria to Proteobacteria to Cyanobacteria features a radical SAM protein, an N-acetyltransferase, an oxidoreductase, and two additional proteins whose functional classes are unclear. The metabolic role of the cluster is probably biosynthetic. This glycosyltransferase, named from member MSMEG_0565 from Mycobacterium smegmatis, occurs in most but not all instances of the cluster. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 274943 [Multi-domain] Cd Length: 373 Bit Score: 82.06 E-value: 4.11e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 94 DVIHAHSAKAGLA-GRLAVRGRIPTVFQphawSFEALEGRAAGLAEAWERFGARWSDRILCVSESERhAGQRAGIAARWS 172
Cdd:TIGR04047 88 DVVHAQDCISGNAlATLRAEGLIPGFVR----TVHHLDDFDDPRLAACQERAIVEADAVLCVSAAWA-AELRAEWGIDAT 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 173 VIHNGVDLGRFRPAPGDAMRSARASLPLladvpPGAPLAVCVGRLSRQKGQDVLLSAWRRVR--VPGARLVLVG------ 244
Cdd:TIGR04047 163 VVPNGVDAARFSPAADAADAALRRRLGL-----RGGPYVLAVGGIEPRKNTIDLLEAFALLRarRPQAQLVIAGgatlfd 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 245 -EGPRGGELRRGA-----PDGVLFAGAARD--VRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLpp 316
Cdd:TIGR04047 238 yDAYRREFRARAAelgvdPGPVVITGPVPDadLPALYRCADAFAFPSLKEGFGLVVLEALASGIPVVASDIAPFTEYL-- 315
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 317 GHLPHCLVPPEDPAALASALTALLGDAGlRAELGSAAGAHARSvFDLTRTSGAVLRLYQE 376
Cdd:TIGR04047 316 GRFDAAWADPSDPDSIADALALALDPAR-RPALRAAGPELAAR-YTWDASARAHLEFYRR 373
|
|
| GT4_ExpE7-like |
cd03823 |
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ... |
12-329 |
1.17e-16 |
|
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).
Pssm-ID: 340850 [Multi-domain] Cd Length: 357 Bit Score: 80.45 E-value: 1.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 12 LTVLHLVQPVE-GGVARVVTDLVAAQVRAGLRPVVACP---PGGGLAEGAAEAGARVWAWPAERVPG------------P 75
Cdd:cd03823 3 LLVNSLYPPQRvGGAEISVHDLAEALVAEGHEVAVLTAgvgPPGQATVARSVVRYRRAPDETLPLALkrrgyelfetynP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 76 RLAREVAAAGRLVRvcaPDVIHAHS---AKAGLAGRLAVRGrIPTVFQPHawSFEALEGRAaglaeawERFGARwSDRIL 152
Cdd:cd03823 83 GLRRLLARLLEDFR---PDVVHTHNlsgLGASLLDAARDLG-IPVVHTLH--DYWLLCPRQ-------FLFKKG-GDAVL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 153 CVSESERHAGQRAGI-AARWSVIHNGVDLGRfrpapgdamrsarasLPLLADVPPGAPLAVC-VGRLSRQKGQDVLLSAW 230
Cdd:cd03823 149 APSRFTANLHEANGLfSARISVIPNAVEPDL---------------APPPRRRPGTERLRFGyIGRLTEEKGIDLLVEAF 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 231 RRVRVPGARLVLVGEGPRGGELRRGAPDGVLFAGAARDVRPWIH--AADVLVLPSRW-EGMALAPLEAMACGRPVLLSDV 307
Cdd:cd03823 214 KRLPREDIELVIAGHGPLSDERQIEGGRRIAFLGRVPTDDIKDFyeKIDVLVVPSIWpEPFGLVVREAIAAGLPVIASDL 293
|
330 340
....*....|....*....|..
gi 1338278072 308 NGARESLPPGHLPHcLVPPEDP 329
Cdd:cd03823 294 GGIAELIQPGVNGL-LFAPGDA 314
|
|
| PLN02871 |
PLN02871 |
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase |
75-353 |
4.21e-16 |
|
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
Pssm-ID: 215469 [Multi-domain] Cd Length: 465 Bit Score: 79.37 E-value: 4.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 75 PRLAREVAAAgrlvrvcAPDVIHAHSAKAGLAGRLAVRG--RIPTV--FQPHAWSFEALEGRAAGLAEAWE--RFGARWS 148
Cdd:PLN02871 134 PRIISEVARF-------KPDLIHASSPGIMVFGALFYAKllCVPLVmsYHTHVPVYIPRYTFSWLVKPMWDiiRFLHRAA 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 149 DRILCVSE--SERHAGQRAGIAARWSVIHNGVDLGRFRPA-PGDAMRSAraslplLADVPPGAPLAVCVGRLSRQKGQDV 225
Cdd:PLN02871 207 DLTLVTSPalGKELEAAGVTAANRIRVWNKGVDSESFHPRfRSEEMRAR------LSGGEPEKPLIVYVGRLGAEKNLDF 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 226 LlsawRRV--RVPGARLVLVGEGPRGGELRR---GAPdgVLFAGAAR--DVRPWIHAADVLVLPSRWEGMALAPLEAMAC 298
Cdd:PLN02871 281 L----KRVmeRLPGARLAFVGDGPYREELEKmfaGTP--TVFTGMLQgdELSQAYASGDVFVMPSESETLGFVVLEAMAS 354
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1338278072 299 GRPVLLSDVNGARESLPPGHLPHC--LVPPEDPAALASALTALLGDAGLRAELGSAA 353
Cdd:PLN02871 355 GVPVVAARAGGIPDIIPPDQEGKTgfLYTPGDVDDCVEKLETLLADPELRERMGAAA 411
|
|
| GT4_WcaC-like |
cd03825 |
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ... |
153-377 |
4.91e-14 |
|
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
Pssm-ID: 340851 [Multi-domain] Cd Length: 364 Bit Score: 72.75 E-value: 4.91e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 153 CVSESERHAGQRAgiaarwSVIHNGVDLGRFRPAPgdaMRSARASLPLLADVPpgAPLAVCVGRLSRQKGQDVLLSAWRR 232
Cdd:cd03825 151 MVRRSPLLKGLPV------VVIPNGIDTEIFAPVD---KAKARKRLGIPQDKK--VILFGAESVTKPRKGFDELIEALKL 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 233 -VRVPGARLVLVGEGPrggELRRGAPDGVLFAGAARDV---RPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVN 308
Cdd:cd03825 220 lATKDDLLLVVFGKND---PQIVILPFDIISLGYIDDDeqlVDIYSAADLFVHPSLADNLPNTLLEAMACGTPVVAFDTG 296
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338278072 309 GARESLPPGHLPHcLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLYQEL 377
Cdd:cd03825 297 GSPEIVQHGVTGY-LVPPGDVQALAEAIEWLLANPKERESLGERARALAENHFDQRVQAQRYLELYKDL 364
|
|
| GT4-like |
cd03813 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
94-374 |
4.91e-13 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340841 [Multi-domain] Cd Length: 474 Bit Score: 70.06 E-value: 4.91e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 94 DVIHAHSAK-AGLAGRLAVRGR-IPTVFQPHA--------------WSFEALEGRaagLAEAWERFGA---RWSDRILCV 154
Cdd:cd03813 175 DLYHSVSTGyAGLLGALARHRRgIPFLLTEHGiytrerkieilqstWIMGYIKKL---WIRFFERLGKlayQQADKIISL 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 155 SESERHAGQRAGI-AARWSVIHNGVDLGRFRPApgdamrsaraslplLADVPPGAPLAV-CVGRLSRQKGQDVLLSAWRR 232
Cdd:cd03813 252 YEGNRRRQIRLGAdPDKTRVIPNGIDIQRFAPA--------------REERPEKEPPVVgLVGRVVPIKDVKTFIRAFKL 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 233 VR--VPGARLVLVG---EGPR-GGELRRGAP-----DGVLFAGAARdVRPWIHAADVLVLPSRWEGMALAPLEAMACGRP 301
Cdd:cd03813 318 VRraMPDAEGWLIGpedEDPEyAQECKRLVAslgleNKVKFLGFQN-IKEYYPKLGLLVLTSISEGQPLVILEAMASGVP 396
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338278072 302 VLLSDVNGARESLPPGHLPHC----LVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLY 374
Cdd:cd03813 397 VVATDVGSCRELIYGADDALGqaglVVPPADPEALAEALIKLLRDPELRQAFGEAGRKRVEKYYTLEGMIDSYRKLY 473
|
|
| PRK10307 |
PRK10307 |
colanic acid biosynthesis glycosyltransferase WcaI; |
131-362 |
9.69e-12 |
|
colanic acid biosynthesis glycosyltransferase WcaI;
Pssm-ID: 236670 [Multi-domain] Cd Length: 412 Bit Score: 66.15 E-value: 9.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 131 GRAAGLAEAWERFGARWSDRILCVSESE-RHAGQRAGIAARWSVIHNGVDLGRFRPAPGDAMRSARASLpllaDVPPGAP 209
Cdd:PRK10307 155 GKVARLATAFERSLLRRFDNVSTISRSMmNKAREKGVAAEKVIFFPNWSEVARFQPVADADVDALRAQL----GLPDGKK 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 210 LAVCVGRLSRQKGQDVLLSAWRRVRV-PGARLVLVGEGPRGGELRRGAPDGVLFAGAARDVRPW-----------IH--- 274
Cdd:PRK10307 231 IVLYSGNIGEKQGLELVIDAARRLRDrPDLIFVICGQGGGKARLEKMAQCRGLPNVHFLPLQPYdrlpallkmadCHllp 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 275 ----AADvLVLPSRWEGMalapleaMACGRPVllsdVNGARESLPPGHLphC-----LVPPEDPAALASALTALLGDAGL 345
Cdd:PRK10307 311 qkagAAD-LVLPSKLTNM-------LASGRNV----VATAEPGTELGQL--VegigvCVEPESVEALVAAIAALARQALL 376
|
250
....*....|....*..
gi 1338278072 346 RAELGSAAGAHARSVFD 362
Cdd:PRK10307 377 RPKLGTVAREYAERTLD 393
|
|
| glgA |
TIGR02095 |
glycogen/starch synthase, ADP-glucose type; This family consists of glycogen (or starch) ... |
93-313 |
3.18e-11 |
|
glycogen/starch synthase, ADP-glucose type; This family consists of glycogen (or starch) synthases that use ADP-glucose (EC 2.4.1.21), rather than UDP-glucose (EC 2.4.1.11) as in animals, as the glucose donor. This enzyme is found in bacteria and plants. Whether the name given is glycogen synthase or starch synthase depends on context, and therefore on substrate. [Energy metabolism, Biosynthesis and degradation of polysaccharides]
Pssm-ID: 273969 [Multi-domain] Cd Length: 473 Bit Score: 64.59 E-value: 3.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 93 PDVIHAHSAKAGLAGRLA----VRGRIPTVFQPHAWSFEAL--EGRAAGLAEAWERF----------------GARWSDR 150
Cdd:TIGR02095 129 PDVVHAHDWHTALVPALLkavyRPNPIKTVFTIHNLAYQGVfpADDFSELGLPPEYFhmeglefygrvnflkgGIVYADR 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 151 ILCVSE--------SERHAGQRAGIAARWSVIH---NGVDLGRFRPAPgDAMRSARASLPLLA---------------DV 204
Cdd:TIGR02095 209 VTTVSPtyareiltPEFGYGLDGVLKARSGKLRgilNGIDTEVWNPAT-DPYLKANYSADDLAgkaenkealqeelglPV 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 205 PPGAPLAVCVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPRG--GELRRGA---PDGV-LFAGAARDVRPWIHA-AD 277
Cdd:TIGR02095 288 DDDVPLFGVISRLTQQKGVDLLLAALPELLELGGQLVVLGTGDPEleEALRELAeryPGNVrVIIGYDEALAHLIYAgAD 367
|
250 260 270
....*....|....*....|....*....|....*.
gi 1338278072 278 VLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARES 313
Cdd:TIGR02095 368 FILMPSRFEPCGLTQLYAMRYGTVPIVRRTGGLADT 403
|
|
| GT5_Glycogen_synthase_DULL1-like |
cd03791 |
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ... |
93-296 |
3.35e-11 |
|
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.
Pssm-ID: 340822 [Multi-domain] Cd Length: 474 Bit Score: 64.51 E-value: 3.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 93 PDVIHAHSAKAGLA-------GRLAVRGRIPTVFQPH------AWSFEALEgraaGLAEAWERF---------------- 143
Cdd:cd03791 129 PDIIHANDWHTALVpaylktrYRGPGFKKIKTVFTIHnlayqgLFPLDTLA----ELGLPPELFhidglefygqinflka 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 144 GARWSDRILCVSES-----------ERHAGQRAGIAARWSVIHNGVDLGRFRPApGDAMRSARASLPLLAD--------- 203
Cdd:cd03791 205 GIVYADRVTTVSPTyakeiltpeygEGLDGVLRARAGKLSGILNGIDYDEWNPA-TDKLIPANYSANDLEGkaenkaalq 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 204 ------VPPGAPLAVCVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPRGGElrrgapdGVLFAGAAR---DVRPWI- 273
Cdd:cd03791 284 kelglpVDPDAPLFGFVGRLTEQKGVDLILDALPELLEEGGQLVVLGSGDPEYE-------QAFRELAERypgKVAVVIg 356
|
250 260 270
....*....|....*....|....*....|...
gi 1338278072 274 ------H----AADVLVLPSRWEGMALAPLEAM 296
Cdd:cd03791 357 fdealaHriyaGADFFLMPSRFEPCGLVQMYAM 389
|
|
| GT4_WfcD-like |
cd03795 |
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ... |
214-365 |
7.39e-11 |
|
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340826 [Multi-domain] Cd Length: 355 Bit Score: 63.06 E-value: 7.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 214 VGRLSRQKGQDVLLSAWRRVRVPgarLVLVGEGPRGGELRRGAP----DGVLFAGAARDVRPWI--HAADVLVLPSRW-- 285
Cdd:cd03795 197 IGRLVYYKGLDYLIEAAQYLNYP---IVIGGEGPLKPDLEAQIElnllDNVKFLGRVDDEEKVIylHLCDVFVFPSVLrs 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 286 EGMALAPLEAMACGRPVLLSDVNGARESLPPGHLPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTR 365
Cdd:cd03795 274 EAFGIVLLEAMMCGKPVISTNIGTGVPYVNNNGETGLVVPPKDPDALAEAIDKLLSDEELRESYGENAKKRFEELFTAEK 353
|
|
| GT4_WbaZ-like |
cd03804 |
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ... |
172-317 |
6.28e-10 |
|
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.
Pssm-ID: 340833 [Multi-domain] Cd Length: 356 Bit Score: 59.99 E-value: 6.28e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 172 SVIHNGVDLGRFRPAPgdamrsaraslplladvpPGAPLAVCVGRLSRQKGQDVLLSAWRRVrvpGARLVLVGEGPRGGE 251
Cdd:cd03804 181 TVIYPPVDTDAFAPAA------------------DKEDYYLTASRLVPYKRIDLAVEAFNEL---PKRLVVIGDGPDLDR 239
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338278072 252 LRRGAPDGVLFAGAARD--VRPWIHAADVLVLPSRwEGMALAPLEAMACGRPVLLSDVNGARESLPPG 317
Cdd:cd03804 240 LRAMASPNVEFLGYQPDevLKELLSKARAFVFAAE-EDFGIVPVEAQACGTPVIAFGKGGALETVRPG 306
|
|
| PRK14099 |
PRK14099 |
glycogen synthase GlgA; |
67-309 |
9.65e-10 |
|
glycogen synthase GlgA;
Pssm-ID: 237610 [Multi-domain] Cd Length: 485 Bit Score: 60.12 E-value: 9.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 67 WPAERVPGPRLAREVAAAGR-LVRVCAPDVIHAHSAKAGLAG---RLAVRGRIPTVFQPHAWSFEA-----------LEG 131
Cdd:PRK14099 107 WPDNAQRFAALARAAAAIGQgLVPGFVPDIVHAHDWQAGLAPaylHYSGRPAPGTVFTIHNLAFQGqfprellgalgLPP 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 132 RAAGLaEAWERFGA--------RWSDRILCVSES--ERHAGQRAGI---------AARWSVIHNGVDLGRFRPApGDAMR 192
Cdd:PRK14099 187 SAFSL-DGVEYYGGigylkaglQLADRITTVSPTyaLEIQGPEAGMgldgllrqrADRLSGILNGIDTAVWNPA-TDELI 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 193 SARASLPLLA---------------DVPPGAPLAVCVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPRggELRRGAP 257
Cdd:PRK14099 265 AATYDVETLAaraankaalqarfglDPDPDALLLGVISRLSWQKGLDLLLEALPTLLGEGAQLALLGSGDA--ELEARFR 342
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338278072 258 DGVL--------FAGAARDVRPWIHA-ADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNG 309
Cdd:PRK14099 343 AAAQaypgqigvVIGYDEALAHLIQAgADALLVPSRFEPCGLTQLCALRYGAVPVVARVGG 403
|
|
| GT4_PIG-A-like |
cd03796 |
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ... |
94-328 |
1.01e-09 |
|
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.
Pssm-ID: 340827 [Multi-domain] Cd Length: 398 Bit Score: 59.56 E-value: 1.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 94 DVIHAHSAKAGLAGRLAVRGR---IPTVFQPHawSFEALEGRAAGLAEAWERFGARWSDRILCVSeserHAGQ-----RA 165
Cdd:cd03796 90 QIVHGHQAFSSLAHEALFHARtlgLKTVFTDH--SLFGFADASSILTNKLLRFSLADIDHVICVS----HTSKentvlRA 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 166 GIA-ARWSVIHNGVDLGRFRPAPGDAmrsaraslplladvPPGAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLVL 242
Cdd:cd03796 164 SLDpRIVSVIPNAVDSSDFTPDPSKP--------------DPNKITIVVISRLVYRKGIDLLVGIIPRIckKHPNVRFII 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 243 VGEGPRGGEL-----RRGAPDGVLFAGAAR--DVRpwihaaDVLVL------PSRWEGMALAPLEAMACGRPVLLSDVNG 309
Cdd:cd03796 230 GGDGPKRIELeemreKYQLQDRVELLGAVPheEVR------DVLVQghiflnTSLTEAFCIAIVEAASCGLLVVSTRVGG 303
|
250
....*....|....*....
gi 1338278072 310 ARESLPPGHLPHCLVPPED 328
Cdd:cd03796 304 IPEVLPPDMILLAEPDPED 322
|
|
| GlgA |
COG0297 |
Glycogen synthase [Carbohydrate transport and metabolism]; |
77-286 |
4.88e-08 |
|
Glycogen synthase [Carbohydrate transport and metabolism];
Pssm-ID: 440066 [Multi-domain] Cd Length: 476 Bit Score: 54.71 E-value: 4.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 77 LAREVAAAGRLVRVcAPDVIHAHSAKAGLA-------GRLAVRGRIPTVF-------Q--------------PHAWSFEA 128
Cdd:COG0297 115 FSRAALELLKGLDW-KPDIIHCHDWQTGLIpallktrYADDPFKRIKTVFtihnlayQgifpaeilellglpPELFTPDG 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 129 LE--GR----AAGLaeawerfgaRWSDRILCVSES------------------ERHAGQRAGIAarwsvihNGVDLGRFR 184
Cdd:COG0297 194 LEfyGQinflKAGI---------VYADRVTTVSPTyareiqtpefgegldgllRARSGKLSGIL-------NGIDYDVWN 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 185 PApGDAMRSARASLPLLA---------------DVPPGAPLAVCVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPRG 249
Cdd:COG0297 258 PA-TDPYLPANYSADDLEgkaankaalqeelglPVDPDAPLIGMVSRLTEQKGLDLLLEALDELLEEDVQLVVLGSGDPE 336
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1338278072 250 -----GELRRGAPDGV-------------LFAGaardvrpwihaADVLVLPSRWE 286
Cdd:COG0297 337 yeeafRELAARYPGRVavyigydealahrIYAG-----------ADFFLMPSRFE 380
|
|
| GT4_ExpC-like |
cd03818 |
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ... |
170-365 |
7.00e-08 |
|
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).
Pssm-ID: 340845 [Multi-domain] Cd Length: 396 Bit Score: 53.91 E-value: 7.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 170 RWSVIHNGVDLGRFRPAPgdamrSARASLPLLADVPPGAPLAVCVGR-LSRQKGQDVLLSAWRRV--RVPGARLVLVG-- 244
Cdd:cd03818 180 RISVIHDGVDTDRLAPDP-----AARLRLLNGTELKAGDPVITYVARnLEPYRGFHVFMRALPRIqaRRPDARVVVVGgd 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 245 ------EGPRGGELR-------RGAPDGVLFAG-AARDV-RPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNG 309
Cdd:cd03818 255 gvsygsPPPDGGSWKqkmlaelGVDLERVHFVGkVPYDQyVRLLQLSDAHVYLTYPFVLSWSLLEAMACGCPVIGSDTAP 334
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1338278072 310 ARESLPPGHlPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTR 365
Cdd:cd03818 335 VREVIRDGR-NGLLVDFFDPDALAAAVLELLEDPDRAAALRRAARRTVERSDSLDV 389
|
|
| PRK15490 |
PRK15490 |
Vi polysaccharide biosynthesis glycosyltransferase TviE; |
236-317 |
1.25e-07 |
|
Vi polysaccharide biosynthesis glycosyltransferase TviE;
Pssm-ID: 185387 [Multi-domain] Cd Length: 578 Bit Score: 53.55 E-value: 1.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 236 PGARLVLVGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGA 310
Cdd:PRK15490 428 PATRFVLVGDGDLRAEAQKraeqlGILERILFVGASRDVGYWLQKMNVFILFSRYEGLPNVLIEAQMVGVPVISTPAGGS 507
|
....*..
gi 1338278072 311 RESLPPG 317
Cdd:PRK15490 508 AECFIEG 514
|
|
| GT4_AviGT4-like |
cd03802 |
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ... |
23-303 |
4.52e-07 |
|
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.
Pssm-ID: 340832 [Multi-domain] Cd Length: 333 Bit Score: 51.13 E-value: 4.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 23 GGVARVVTDLVAAQVRAG-------------LRPVVACPPggglaegaaeagarVWAWPAERVPGPRLAREVAAAGRLVR 89
Cdd:cd03802 18 GGTELVVSALTEGLVRRGhevtlfapgdshtSAPLVAVIP--------------RALRLDPIPQESKLAELLEALEVQLR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 90 VCAPDVIHAHSAkaGLAGRLAVRGRIPTVfqphawsfEALEGRAagLAEAWERFGARWSDRILCVSeserHAGQRAGIAA 169
Cdd:cd03802 84 ASDFDVIHNHSY--DWLPPFAPLIGTPFV--------TTLHGPS--IPPSLAIYAAEPPVNYVSIS----DAQRAATPPI 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 170 RW-SVIHNGVDLGRFRPAPgdamrsaraslplladvPPGAPLAVcVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPR 248
Cdd:cd03802 148 DYlTVVHNGLDPADYRFQP-----------------DPEDYLAF-LGRIAPEKGLEDAIRVARRAGLPLKIAGKVRDEDY 209
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1338278072 249 GGELRRGAP-DGVLFAGAARDVR--PWIHAADVLVLPSRW-EGMALAPLEAMACGRPVL 303
Cdd:cd03802 210 FYYLQEPLPgPRIEFIGEVGHDEkqELLGGARALLFPINWdEPFGLVMIEAMACGTPVI 268
|
|
| GT4_mannosyltransferase-like |
cd03822 |
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ... |
141-329 |
9.30e-06 |
|
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.
Pssm-ID: 340849 [Multi-domain] Cd Length: 370 Bit Score: 47.38 E-value: 9.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 141 ERFGARWSDRILCVSESERHAGQRAGI-AARWSVIHNGVdlgrFRPAPGDAMRSARASLPLladvppGAPLAVCVGRLSR 219
Cdd:cd03822 129 FRIATLSERVVVMAPISRFLLVRIKLIpAVNIEVIPHGV----PEVPQDPTTALKRLLLPE------GKKVILTFGFIGP 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 220 QKGQDVLLSAWRRVR--VPGARLVLVGEgpRGGELRRGAPDGVLFAGAAR-----------------DVRPWIHAADVLV 280
Cdd:cd03822 199 GKGLEILLEALPELKaeFPDVRLVIAGE--LHPSLARYEGERYRKAAIEElglqdhvdfhnnflpeeEVPRYISAADVVV 276
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1338278072 281 LP--SRWEGMALAPLEAMACGRPVLLSDVNGAREslppghLPHC----LVPPEDP 329
Cdd:cd03822 277 LPylNTEQSSSGTLSYAIACGKPVISTPLRHAEE------LLADgrgvLVPFDDP 325
|
|
| Glyco4_Geo_Pelo |
NF038229 |
GPMC system family 4 glycosyltransferase; Members of this family are family 4 ... |
274-379 |
1.10e-05 |
|
GPMC system family 4 glycosyltransferase; Members of this family are family 4 glycosyltransferases of the GPMC (Geobacter/Pelobacter Mystery Cassette) system, in which the most distinctive signature is the TIGR04442 protein family.
Pssm-ID: 439530 [Multi-domain] Cd Length: 338 Bit Score: 46.90 E-value: 1.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 274 HAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGAREslppghlphcLVPPE-------DPAALASALTALLGDAGLR 346
Cdd:NF038229 236 RRADVVLNNSLFEGMANALLEAMALGRPVLARDIPGNRS----------VVRPGvtgllyrDEAEFLRQARQLLQDPALR 305
|
90 100 110
....*....|....*....|....*....|...
gi 1338278072 347 AELGSAAGAHARSVFDLTRTSGAVLRLYQELVG 379
Cdd:NF038229 306 RRLGRPGRQLVRERYSPEREAEAYLRLYRAVLA 338
|
|
| PRK15179 |
PRK15179 |
Vi polysaccharide biosynthesis protein TviE; Provisional |
234-375 |
3.97e-05 |
|
Vi polysaccharide biosynthesis protein TviE; Provisional
Pssm-ID: 185101 [Multi-domain] Cd Length: 694 Bit Score: 45.80 E-value: 3.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 234 RVPGARLVLVGEGP-----RGGELRRGAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVN 308
Cdd:PRK15179 545 SHPKVRFIMVGGGPllesvREFAQRLGMGERILFTGLSRRVGYWLTQFNAFLLLSRFEGLPNVLIEAQFSGVPVVTTLAG 624
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338278072 309 GARESLPPGHLPHCLVP-----PEDPAALASALTALLGDAGLRAElgsaAGAHARSVFDLTRTSGAVLRLYQ 375
Cdd:PRK15179 625 GAGEAVQEGVTGLTLPAdtvtaPDVAEALARIHDMCAADPGIARK----AADWASARFSLNQMIASTVRCYQ 692
|
|
| GT4_AmsK-like |
cd03799 |
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ... |
92-328 |
1.84e-04 |
|
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.
Pssm-ID: 340829 [Multi-domain] Cd Length: 350 Bit Score: 43.21 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 92 APDVIHAHSAKAGLAGRLAVR-----GRIPTVFQPHAWS-FEALEGRAAglaeaWERFGARwSDRILCVSESERHAGQRA 165
Cdd:cd03799 70 AYDIIHCQFGPLGALGALLRRlkvlkGKLVTSFRGYDISmYVILEGNKV-----YPQLFAQ-GDLFLPNCELFKHRLIAL 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 166 GIAARWSVIHN-GVDLGRFRPAPgdamrsaraslpllADVPPGAPLAVC-VGRLSRQKGQDVLLSAWRRV--RVPGARLV 241
Cdd:cd03799 144 GCDEKKIIVHRsGIDCNKFRFKP--------------RYLPLDGKIRILtVGRLTEKKGLEYAIEAVAKLaqKYPNIEYQ 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 242 LVGEGPRGGELRRGAPDG-----VLFAGAAR--DVRPWIHAADVLVLPS------RWEGMALAPLEAMACGRPVLLSDVN 308
Cdd:cd03799 210 IIGDGDLKEQLQQLIQELnigdcVKLLGWKPqeEIIEILDEADIFIAPSvtaadgDQDGPPNTLKEAMAMGLPVISTEHG 289
|
250 260
....*....|....*....|
gi 1338278072 309 GARESLPPGhLPHCLVPPED 328
Cdd:cd03799 290 GIPELVEDG-VSGFLVPERD 308
|
|
| PelF |
NF038011 |
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ... |
168-312 |
1.86e-04 |
|
GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.
Pssm-ID: 411604 [Multi-domain] Cd Length: 489 Bit Score: 43.38 E-value: 1.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 168 AARWSVIHNGVDLGRFRPApgdamRSARaslplladvPPGAPLAVC-VGRLSRQKGQDVLLSAWRRV--RVPGARLVLVG 244
Cdd:NF038011 279 PERTRVIPNGIDLPRLAPL-----RAQR---------PAGIPPVVGlIGRVVPIKDIKTFIRAMRTVvrAMPEAEGWIVG 344
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338278072 245 ---EGPRGGELRR------GAPDGVLFAGAAR--DVRPWIhaaDVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARE 312
Cdd:NF038011 345 peeEDPAYAAECRslvaslGLQDKVKFLGFQKidDLLPQV---GLMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQ 420
|
|
| GT4_GtfA-like |
cd04949 |
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ... |
214-312 |
2.49e-04 |
|
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340855 [Multi-domain] Cd Length: 328 Bit Score: 42.67 E-value: 2.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 214 VGRLSRQKGQDVLLSAWRRVR--VPGARLVLVGEG-----PRGGELRRGAPDGVLFAGAARDVRPWIHAADVLVLPSRWE 286
Cdd:cd04949 166 ISRLAPEKQLDHLIEAVAKAVkkVPEITLDIYGYGeerekLKKLIEELHLEDNVFLKGYHSNLDQEYQDAYLSLLTSQME 245
|
90 100
....*....|....*....|....*..
gi 1338278072 287 GMALAPLEAMACGRPVLLSDVN-GARE 312
Cdd:cd04949 246 GFGLTLMEAIGHGLPVVSYDVKyGPSE 272
|
|
| PRK15484 |
PRK15484 |
lipopolysaccharide N-acetylglucosaminyltransferase; |
168-312 |
6.50e-04 |
|
lipopolysaccharide N-acetylglucosaminyltransferase;
Pssm-ID: 185381 [Multi-domain] Cd Length: 380 Bit Score: 41.70 E-value: 6.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 168 AARWSVIHNGVDLGRFRPAPGDAMRSAraslpllADVPPGAPLAVCVGRLSRQKGQDVLLSAWRRVRV--PGARLVLVGE 245
Cdd:PRK15484 160 NADISIVPNGFCLETYQSNPQPNLRQQ-------LNISPDETVLLYAGRISPDKGILLLMQAFEKLATahSNLKLVVVGD 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 246 --GPRGGE-----------LRRGAPDGVLFAGAARD-VRPWIHAADVLVLPSRW-EGMALAPLEAMACGRPVLLSDVNGA 310
Cdd:PRK15484 233 ptASSKGEkaayqkkvleaAKRIGDRCIMLGGQPPEkMHNYYPLADLVVVPSQVeEAFCMVAVEAMAAGKPVLASTKGGI 312
|
..
gi 1338278072 311 RE 312
Cdd:PRK15484 313 TE 314
|
|
| glgA |
PRK00654 |
glycogen synthase GlgA; |
93-299 |
6.87e-04 |
|
glycogen synthase GlgA;
Pssm-ID: 234809 [Multi-domain] Cd Length: 466 Bit Score: 41.64 E-value: 6.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 93 PDVIHAHSAKAGLA------GRLAVRGRIPTVFQPH------AWSFEALegRAAGL-AEAWERFGARW------------ 147
Cdd:PRK00654 119 PDIVHAHDWHTGLIpallkeKYWRGYPDIKTVFTIHnlayqgLFPAEIL--GELGLpAEAFHLEGLEFygqisflkagly 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 148 -SDRILCVSESerHA--------GQR-----AGIAARWSVIHNGVDLGRFRPApGDAMRSARASLPLLAD---------- 203
Cdd:PRK00654 197 yADRVTTVSPT--YAreittpefGYGlegllRARSGKLSGILNGIDYDIWNPE-TDPLLAANYSADDLEGkaenkralqe 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 204 ----VPPGAPLAVCVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPRG--GELRRGA---PDGVlfaGA--------A 266
Cdd:PRK00654 274 rfglPDDDAPLFAMVSRLTEQKGLDLVLEALPELLEQGGQLVLLGTGDPEleEAFRALAaryPGKV---GVqigydealA 350
|
250 260 270
....*....|....*....|....*....|....
gi 1338278072 267 RdvrpWIHA-ADVLVLPSRWEGMALAPLEAMACG 299
Cdd:PRK00654 351 H----RIYAgADMFLMPSRFEPCGLTQLYALRYG 380
|
|
| GT4_trehalose_phosphorylase |
cd03792 |
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ... |
203-365 |
2.16e-03 |
|
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.
Pssm-ID: 340823 [Multi-domain] Cd Length: 378 Bit Score: 40.00 E-value: 2.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 203 DVPPGAPLAVCVGRLSRQKGQDVLLSAWRRVR--VPGARLVLVGEGPRGGelrrgaPDGVLF-------AGAARDvrpwI 273
Cdd:cd03792 192 VIDPERPYILQVARFDPSKDPLGVIDAYKLFKrrAEEPQLVICGHGAVDD------PEGSVVyeevmeyAGDDHD----I 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 274 H----------------AADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLPHcLVPPEDPAALASALT 337
Cdd:cd03792 262 HvlrlppsdqeinalqrAATVVLQLSTREGFGLTVSEALWKGKPVIATPAGGIPLQVIDGETGF-LVNSVEGAAVRILRL 340
|
170 180
....*....|....*....|....*...
gi 1338278072 338 ALlgDAGLRAELGSAAGAHARSVFDLTR 365
Cdd:cd03792 341 LT--DPELRRKMGLAAREHVRDNFLITG 366
|
|
| GT4_AmsK-like |
cd04946 |
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ... |
274-312 |
9.09e-03 |
|
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.
Pssm-ID: 340854 [Multi-domain] Cd Length: 401 Bit Score: 37.82 E-value: 9.09e-03
10 20 30
....*....|....*....|....*....|....*....
gi 1338278072 274 HAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARE 312
Cdd:cd04946 303 NDVDVFVNVSESEGIPVSIMEAISFGIPVIATNVGGTRE 341
|
|
|