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Conserved domains on  [gi|1338278072|ref|WP_103505241|]
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MULTISPECIES: glycosyltransferase [Streptomyces]

Protein Classification

glycosyltransferase family protein( domain architecture ID 56)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Glycosyltransferase_GTB-type super family cl10013
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
93-363 1.18e-54

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


The actual alignment was detected with superfamily member cd03808:

Pssm-ID: 471961 [Multi-domain]  Cd Length: 358  Bit Score: 183.95  E-value: 1.18e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  93 PDVIHAHSAKAGLAGRLAVR--GRIPTVFQPHAWSFEALEG-RAAGLAEAWERFGARWSDRILCVSESERHAGQRAGIAA 169
Cdd:cd03808    82 PDIVHCHTPKPGILGRLAARlaGVPKVIYTVHGLGFVFTEGkLLRLLYLLLEKLALLFTDKVIFVNEDDRDLAIKKGIIK 161
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 170 RWSVI---HNGVDLGRFRPAPGDAmrsaraslplladvPPGAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLVLVG 244
Cdd:cd03808   162 KKKTVlipGSGVDLDRFQYSPESL--------------PSEKVVFLFVARLLKDKGIDELIEAAKILkkKGPNVRFLLVG 227
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 245 EGPRGGEL-----RRGAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGhL 319
Cdd:cd03808   228 DGELENPSeilieKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELVIDG-V 306
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1338278072 320 PHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDL 363
Cdd:cd03808   307 NGFLVPPGDVEALADAIEKLIEDPELRKEMGEAARKRVEEKFDE 350
 
Name Accession Description Interval E-value
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
93-363 1.18e-54

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 183.95  E-value: 1.18e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  93 PDVIHAHSAKAGLAGRLAVR--GRIPTVFQPHAWSFEALEG-RAAGLAEAWERFGARWSDRILCVSESERHAGQRAGIAA 169
Cdd:cd03808    82 PDIVHCHTPKPGILGRLAARlaGVPKVIYTVHGLGFVFTEGkLLRLLYLLLEKLALLFTDKVIFVNEDDRDLAIKKGIIK 161
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 170 RWSVI---HNGVDLGRFRPAPGDAmrsaraslplladvPPGAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLVLVG 244
Cdd:cd03808   162 KKKTVlipGSGVDLDRFQYSPESL--------------PSEKVVFLFVARLLKDKGIDELIEAAKILkkKGPNVRFLLVG 227
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 245 EGPRGGEL-----RRGAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGhL 319
Cdd:cd03808   228 DGELENPSeilieKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELVIDG-V 306
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1338278072 320 PHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDL 363
Cdd:cd03808   307 NGFLVPPGDVEALADAIEKLIEDPELRKEMGEAARKRVEEKFDE 350
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
208-329 1.42e-31

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 116.46  E-value: 1.42e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 208 APLAVCVGRLS-RQKGQDVLLSAWRRVR--VPGARLVLVGEGPRGG--ELRRGAPDGVLFAGAARDVRPWIHAADVLVLP 282
Cdd:pfam13692   1 RPVILFVGRLHpNVKGVDYLLEAVPLLRkrDNDVRLVIVGDGPEEEleELAAGLEDRVIFTGFVEDLAELLAAADVFVLP 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1338278072 283 SRWEGMALAPLEAMACGRPVLLSDVNGARESLPpgHLPHCLVPPEDP 329
Cdd:pfam13692  81 SLYEGFGLKLLEAMAAGLPVVATDVGGIPELVD--GENGLLVPPGDP 125
stp2 TIGR03088
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ...
168-378 2.85e-23

sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.


Pssm-ID: 132132 [Multi-domain]  Cd Length: 374  Bit Score: 99.80  E-value: 2.85e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 168 AARWSVIHNGVDLGRFRPAPGDamRSARASLPLLADVPPgapLAVCVGRLSRQKGQDVLLSAW------RRVRVPGARLV 241
Cdd:TIGR03088 159 PAKIHQIYNGVDTERFHPSRGD--RSPILPPDFFADESV---VVGTVGRLQAVKDQPTLVRAFallvrqLPEGAERLRLV 233
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 242 LVGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPP 316
Cdd:TIGR03088 234 IVGDGPARGACEQmvraaGLAHLVWLPGERDDVPALMQALDLFVLPSLAEGISNTILEAMASGLPVIATAVGGNPELVQH 313
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338278072 317 GhLPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLYQELV 378
Cdd:TIGR03088 314 G-VTGALVPPGDAVALARALQPYVSDPAARRAHGAAGRARAEQQFSINAMVAAYAGLYDQLL 374
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
272-379 1.02e-18

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 81.19  E-value: 1.02e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 272 WIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLPhCLVPPEDPAALASALTALLGDAGLRAELGS 351
Cdd:COG0438    17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETG-LLVPPGDPEALAEAILRLLEDPELRRRLGE 95
                          90       100
                  ....*....|....*....|....*...
gi 1338278072 352 AAGAHARSVFDLTRTSGAVLRLYQELVG 379
Cdd:COG0438    96 AARERAEERFSWEAIAERLLALYEELLA 123
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
75-353 4.21e-16

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 79.37  E-value: 4.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  75 PRLAREVAAAgrlvrvcAPDVIHAHSAKAGLAGRLAVRG--RIPTV--FQPHAWSFEALEGRAAGLAEAWE--RFGARWS 148
Cdd:PLN02871  134 PRIISEVARF-------KPDLIHASSPGIMVFGALFYAKllCVPLVmsYHTHVPVYIPRYTFSWLVKPMWDiiRFLHRAA 206
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 149 DRILCVSE--SERHAGQRAGIAARWSVIHNGVDLGRFRPA-PGDAMRSAraslplLADVPPGAPLAVCVGRLSRQKGQDV 225
Cdd:PLN02871  207 DLTLVTSPalGKELEAAGVTAANRIRVWNKGVDSESFHPRfRSEEMRAR------LSGGEPEKPLIVYVGRLGAEKNLDF 280
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 226 LlsawRRV--RVPGARLVLVGEGPRGGELRR---GAPdgVLFAGAAR--DVRPWIHAADVLVLPSRWEGMALAPLEAMAC 298
Cdd:PLN02871  281 L----KRVmeRLPGARLAFVGDGPYREELEKmfaGTP--TVFTGMLQgdELSQAYASGDVFVMPSESETLGFVVLEAMAS 354
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1338278072 299 GRPVLLSDVNGARESLPPGHLPHC--LVPPEDPAALASALTALLGDAGLRAELGSAA 353
Cdd:PLN02871  355 GVPVVAARAGGIPDIIPPDQEGKTgfLYTPGDVDDCVEKLETLLADPELRERMGAAA 411
Glyco4_Geo_Pelo NF038229
GPMC system family 4 glycosyltransferase; Members of this family are family 4 ...
274-379 1.10e-05

GPMC system family 4 glycosyltransferase; Members of this family are family 4 glycosyltransferases of the GPMC (Geobacter/Pelobacter Mystery Cassette) system, in which the most distinctive signature is the TIGR04442 protein family.


Pssm-ID: 439530 [Multi-domain]  Cd Length: 338  Bit Score: 46.90  E-value: 1.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 274 HAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGAREslppghlphcLVPPE-------DPAALASALTALLGDAGLR 346
Cdd:NF038229  236 RRADVVLNNSLFEGMANALLEAMALGRPVLARDIPGNRS----------VVRPGvtgllyrDEAEFLRQARQLLQDPALR 305
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1338278072 347 AELGSAAGAHARSVFDLTRTSGAVLRLYQELVG 379
Cdd:NF038229  306 RRLGRPGRQLVRERYSPEREAEAYLRLYRAVLA 338
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
168-312 1.86e-04

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 43.38  E-value: 1.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 168 AARWSVIHNGVDLGRFRPApgdamRSARaslplladvPPGAPLAVC-VGRLSRQKGQDVLLSAWRRV--RVPGARLVLVG 244
Cdd:NF038011  279 PERTRVIPNGIDLPRLAPL-----RAQR---------PAGIPPVVGlIGRVVPIKDIKTFIRAMRTVvrAMPEAEGWIVG 344
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338278072 245 ---EGPRGGELRR------GAPDGVLFAGAAR--DVRPWIhaaDVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARE 312
Cdd:NF038011  345 peeEDPAYAAECRslvaslGLQDKVKFLGFQKidDLLPQV---GLMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQ 420
 
Name Accession Description Interval E-value
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
93-363 1.18e-54

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 183.95  E-value: 1.18e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  93 PDVIHAHSAKAGLAGRLAVR--GRIPTVFQPHAWSFEALEG-RAAGLAEAWERFGARWSDRILCVSESERHAGQRAGIAA 169
Cdd:cd03808    82 PDIVHCHTPKPGILGRLAARlaGVPKVIYTVHGLGFVFTEGkLLRLLYLLLEKLALLFTDKVIFVNEDDRDLAIKKGIIK 161
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 170 RWSVI---HNGVDLGRFRPAPGDAmrsaraslplladvPPGAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLVLVG 244
Cdd:cd03808   162 KKKTVlipGSGVDLDRFQYSPESL--------------PSEKVVFLFVARLLKDKGIDELIEAAKILkkKGPNVRFLLVG 227
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 245 EGPRGGEL-----RRGAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGhL 319
Cdd:cd03808   228 DGELENPSeilieKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELVIDG-V 306
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1338278072 320 PHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDL 363
Cdd:cd03808   307 NGFLVPPGDVEALADAIEKLIEDPELRKEMGEAARKRVEEKFDE 350
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
14-375 6.60e-54

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 182.35  E-value: 6.60e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  14 VLHLVQ---PVEGGVARVVTDLVAAQVRAGLRPVVACPPGGGLAEGAAEAGARVWAWPAERVPgPRLAREVAAAGRLVRV 90
Cdd:cd03801     2 ILLLSPelpPPVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAAL-LRARRLLRELRPLLRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  91 CAPDVIHAHSAKAGLAGRLAVRG-RIPTVFQPHAWSFEALEGRAAG----LAEAWERFgaRWSDRILCVSESERHAGQRA 165
Cdd:cd03801    81 RKFDVVHAHGLLAALLAALLALLlGAPLVVTLHGAEPGRLLLLLAAerrlLARAEALL--RRADAVIAVSEALRDELRAL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 166 GIA--ARWSVIHNGVDLGRFRPApgdamrsARASLPLladvPPGAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLV 241
Cdd:cd03801   159 GGIppEKIVVIPNGVDLERFSPP-------LRRKLGI----PPDRPVLLFVGRLSPRKGVDLLLEALAKLlrRGPDVRLV 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 242 LVG-EGPRGGELRR---GAPDGVLFAGA--ARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLP 315
Cdd:cd03801   228 IVGgDGPLRAELEElelGLGDRVRFLGFvpDEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLPEVVE 307
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 316 PGHLpHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLYQ 375
Cdd:cd03801   308 DGEG-GLVVPPDDVEALADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLYR 366
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
86-374 1.13e-40

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 147.46  E-value: 1.13e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  86 RLVRVCAPDVIHAHSAKAGLAGRLAVRG-RIPTVFqphaWSFE--ALEGRAAGLAEAWERFGARWSDRILCVSESERHAG 162
Cdd:cd03807    73 KLIRKRNPDVVHTWMYHADLIGGLAAKLaGGVKVI----WSVRssNIPQRLTRLVRKLCLLLSKFSPATVANSSAVAEFH 148
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 163 QRAGIAARWS-VIHNGVDLGRFRPAPGDAmRSARASLPLLADVPpgapLAVCVGRLSRQKGQDVLLSAWRRV--RVPGAR 239
Cdd:cd03807   149 QEQGYAKNKIvVIYNGIDLFKLSPDDASR-ARARRRLGLAEDRR----VIGIVGRLHPVKDHSDLLRAAALLveTHPDLR 223
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 240 LVLVGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESL 314
Cdd:cd03807   224 LLLVGRGPERPNLERlllelGLEDRVHLLGERSDVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVGGAAELV 303
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 315 PPGhlPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLY 374
Cdd:cd03807   304 DDG--TGFLVPAGDPQALADAIRALLEDPEKRARLGRAARERIANEFSIDAMVRRYETLY 361
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
23-362 1.91e-40

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 146.35  E-value: 1.91e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  23 GGVARVVTDLVAAQVRAGLRP--VVACPPGGGLAEGAAEAGARVWAWPAERVPGPRLAREVAAAGRLVRVCAPDVIHAHS 100
Cdd:cd03811    12 GGAERVLLNLANALDKRGYDVtlVLLRDEGDLDKQLNGDVKLIRLLIRVLKLIKLGLLKAILKLKRILKRAKPDVVISFL 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 101 AKAGLAGRLAVRGRIPTVFQPHAWSFEALEGRAAGLaeaWERFGARWSDRILCVSESERHAGQRAGI--AARWSVIHNGV 178
Cdd:cd03811    92 GFATYIVAKLAAARSKVIAWIHSSLSKLYYLKKKLL---LKLKLYKKADKIVCVSKGIKEDLIRLGPspPEKIEVIYNPI 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 179 DLGRFRpapgdamrsARASLPLLADvPPGAPLAVCVGRLSRQKGQDVLLSAWRRVR--VPGARLVLVGEGPRGGELRR-- 254
Cdd:cd03811   169 DIDRIR---------ALAKEPILNE-PEDGPVILAVGRLDPQKGHDLLIEAFAKLRkkYPDVKLVILGDGPLREELEKla 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 255 ---GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHlpHCLVPPEDPAA 331
Cdd:cd03811   239 kelGLAERVIFLGFQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPGPREILDDGE--NGLLVPDGDAA 316
                         330       340       350
                  ....*....|....*....|....*....|.
gi 1338278072 332 LASALTALLGDAGLRAELGSAAGAHARSVFD 362
Cdd:cd03811   317 ALAGILAALLQKKLDAALRERLAKAQEAVFR 347
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
19-365 2.69e-36

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 135.18  E-value: 2.69e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  19 QPVEGGVARVVTDLVAAQVRAGLRPVVACPpgggLAEGAAEAGARVWAWPAERVPGPRLAREVAAAGRLVRVCAPDVIHA 98
Cdd:cd03819     7 ALEIGGAETYILDLARALAERGHRVLVVTA----GGPLLPRLRQIGIGLPGLKVPLLRALLGNVRLARLIRRERIDLIHA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  99 HSAKAGLAGRLAVRG-RIPTVFQPHawSFEALEGRAAGLAEAWERFGarwsDRILCVSESERHAGQRAG--IAARWSVIH 175
Cdd:cd03819    83 HSRAPAWLGWLASRLtGVPLVTTVH--GSYLATYHPKDFALAVRARG----DRVIAVSELVRDHLIEALgvDPERIRVIP 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 176 NGVDLGRFRPAPGDAMRSAraslpllADVPPGAPLAVCVGRLSRQKGQDVLLSAWRRV-RVPGARLVLVGEGPRGGELRR 254
Cdd:cd03819   157 NGVDTDRFPPEAEAEERAQ-------LGLPEGKPVVGYVGRLSPEKGWLLLVDAAAELkDEPDFRLLVAGDGPERDEIRR 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 255 -----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGhLPHCLVPPEDP 329
Cdd:cd03819   230 lverlGLRDRVTFTGFREDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGAREIVVHG-RTGLLVPPGDA 308
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1338278072 330 AALASALTALLGDAGLRAELGSAAGAHARSVFDLTR 365
Cdd:cd03819   309 EALADAIRAAKLLPEAREKLQAAAALTEAVRELLLR 344
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
20-358 1.81e-34

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 130.88  E-value: 1.81e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  20 PVEGGVARVVTDLVAAQVRAGLRPVVACPPGGGLAEGAAEAGARVWAWPAERVPGPRLAreVAAAGRLVRVC---APDVI 96
Cdd:cd03814    11 PQVNGVVRTLERLVDHLRRRGHEVRVVAPGPFDEAESAEGRVVSVPSFPLPFYPEYRLA--LPLPRRVRRLIkefQPDII 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  97 HAHS-AKAGLAGR-LAVRGRIPTVFQPHAWSFEALEGRAAGLAEAWERFGARW----SDRILCVSESERHAGQRAGI--A 168
Cdd:cd03814    89 HIATpGPLGLAALrAARRLGLPVVTSYHTDFPEYLSYYTLGPLSWLAWAYLRWfhnpFDTTLVPSPSIARELEGHGFerV 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 169 ARWSvihNGVDLGRFRPAPGD-AMRSARAslplladvPPGAPLAVCVGRLSRQKGQDVLLSAWRR-VRVPGARLVLVGEG 246
Cdd:cd03814   169 RLWP---RGVDTELFHPSRRDaALRRRLG--------PPGRPLLLYVGRLAPEKNLEALLDADLPlAASPPVRLVVVGDG 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 247 PRGGELRRGAPDgVLFAGAA-RDVRPWIHA-ADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLPhCLV 324
Cdd:cd03814   238 PARAELEARGPD-VIFTGFLtGEELARAYAsADVFVFPSRTETFGLVVLEAMASGLPVVAADAGGPRDIVRPGGTG-ALV 315
                         330       340       350
                  ....*....|....*....|....*....|....
gi 1338278072 325 PPEDPAALASALTALLGDAGLRAELGSAAGAHAR 358
Cdd:cd03814   316 EPGDAAAFAAALRALLEDPELRRRMAARARAEAE 349
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
208-329 1.42e-31

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 116.46  E-value: 1.42e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 208 APLAVCVGRLS-RQKGQDVLLSAWRRVR--VPGARLVLVGEGPRGG--ELRRGAPDGVLFAGAARDVRPWIHAADVLVLP 282
Cdd:pfam13692   1 RPVILFVGRLHpNVKGVDYLLEAVPLLRkrDNDVRLVIVGDGPEEEleELAAGLEDRVIFTGFVEDLAELLAAADVFVLP 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1338278072 283 SRWEGMALAPLEAMACGRPVLLSDVNGARESLPpgHLPHCLVPPEDP 329
Cdd:pfam13692  81 SLYEGFGLKLLEAMAAGLPVVATDVGGIPELVD--GENGLLVPPGDP 125
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
93-361 3.12e-30

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 119.65  E-value: 3.12e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  93 PDVIHAHSAKAGLAG-RLAVRGRIPTVFQPHA------------WSFEALEGRAAglaeawERFGARWSDRILcVSESER 159
Cdd:cd03800   102 YDLIHSHYWDSGLVGaLLARRLGVPLVHTFHSlgrvkyrhlgaqDTYHPSLRITA------EEQILEAADRVI-ASTPQE 174
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 160 HAGQRAGIAA---RWSVIHNGVDLGRFRPAPGDAMRSARASLPlladvpPGAPLAVCVGRLSRQKGQDVLLSAW--RRVR 234
Cdd:cd03800   175 ADELISLYGAdpsRINVVPPGVDLERFFPVDRAEARRARLLLP------PDKPVVLALGRLDPRKGIDTLVRAFaqLPEL 248
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 235 VPGARLVLVGeGPRGGELRRGAP------------DGVLFAGAAR--DVRPWIHAADVLVLPSRWEGMALAPLEAMACGR 300
Cdd:cd03800   249 RELANLVLVG-GPSDDPLSMDREelaelaeelgliDRVRFPGRVSrdDLPELYRAADVFVVPSLYEPFGLTAIEAMACGT 327
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338278072 301 PVLLSDVNGARESLPPGHlPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVF 361
Cdd:cd03800   328 PVVATAVGGLQDIVRDGR-TGLLVDPHDPEALAAALRRLLDDPALWQRLSRAGLERARAHY 387
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
93-329 1.57e-29

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 117.48  E-value: 1.57e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  93 PDVIHAHSAKAGLAGRLAVRGRIPTVFQPHAWSFEALEGRAAGLAEAWERFGARWSDRILCVSESERHAGQRAGIAA-RW 171
Cdd:cd03798    96 PDLIHAHFAYPAGFAAALLARLYGVPYVVTEHGSDINVFPPRSLLRKLLRWALRRAARVIAVSKALAEELVALGVPRdRV 175
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 172 SVIHNGVDLGRFRPAPgdamrsaraslpLLADVPPGAPLAVCVGRLSRQKGQDVLLSA--WRRVRVPGARLVLVGEGPRG 249
Cdd:cd03798   176 DVIPNGVDPARFQPED------------RGLGLPLDAFVILFVGRLIPRKGIDLLLEAfaRLAKARPDVVLLIVGDGPLR 243
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 250 GELRRGAP-----DGVLFAGA--ARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHlPHC 322
Cdd:cd03798   244 EALRALAEdlglgDRVTFTGRlpHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVGGIPEVVGDPE-TGL 322

                  ....*..
gi 1338278072 323 LVPPEDP 329
Cdd:cd03798   323 LVPPGDA 329
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
209-329 6.67e-27

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 104.66  E-value: 6.67e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 209 PLAVCVGRLSRQKGQDVLLSAWRRVR--VPGARLVLVGEGPRGGELR-----RGAPDGVLFAGAARDVRPW--IHAADVL 279
Cdd:pfam00534   3 KIILFVGRLEPEKGLDLLIKAFALLKekNPNLKLVIAGDGEEEKRLKklaekLGLGDNVIFLGFVSDEDLPelLKIADVF 82
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1338278072 280 VLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHlPHCLVPPEDP 329
Cdd:pfam00534  83 VLPSRYEGFGIVLLEAMACGLPVIASDVGGPPEVVKDGE-TGFLVKPNNA 131
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
71-377 5.54e-26

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 107.36  E-value: 5.54e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  71 RVPGPRLAREvaAAGRLVRVCAPDVIHAHSA-KAGLAG-RLAVRGRIPTV----FQPHAWSFEALEGRAaglaeaWERFG 144
Cdd:cd03817    65 RQHIPFPFKK--AVIDRIKELGPDIIHTHTPfSLGKLGlRIARKLKIPIVhtyhTMYEDYLHYIPKGKL------LVKAV 136
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 145 ARW--------SDRILCVSESERHAGQRAGIAARWSVIHNGVDLGRFRPAPGDAmrsARASLPLladvPPGAPLAVCVGR 216
Cdd:cd03817   137 VRKlvrrfynhTDAVIAPSEKIKDTLREYGVKGPIEVIPNGIDLDKFEKPLNTE---ERRKLGL----PPDEPILLYVGR 209
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 217 LSRQKGQDVLLSAWRRVR-VPGARLVLVGEGPRGGELRR-----GAPDGVLFAGaardVRPW------IHAADVLVLPSR 284
Cdd:cd03817   210 LAKEKNIDFLLRAFAELKkEPNIKLVIVGDGPEREELKElarelGLADKVIFTG----FVPReelpeyYKAADLFVFAST 285
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 285 WEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLpHCLVPPEDPAALASALTALLGDAgLRAELGSAAGAHARSvFDLT 364
Cdd:cd03817   286 TETQGLVYLEAMAAGLPVVAAKDPAASELVEDGEN-GFLFEPNDETLAEKLLHLRENLE-LLRKLSKNAEISARE-FAFA 362
                         330
                  ....*....|...
gi 1338278072 365 RtsgAVLRLYQEL 377
Cdd:cd03817   363 K---SVEKLYEEV 372
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
71-369 1.81e-25

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 106.00  E-value: 1.81e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  71 RVPGPRLAREVAAAGRLVRVCAPDVIHAHSAKAG-LAGRLAVRGRIPTVFQPHAWSFEALEGRAAGLAEAWERFGARW-- 147
Cdd:cd05844    60 RQMAQRLLGWSAPRLGGAAGLAPALVHAHFGRDGvYALPLARALGVPLVVTFHGFDITTSRAWLAASPGWPSQFQRHRra 139
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 148 ----SDRILCVSESERHAGQRAGIAA-RWSVIHNGVDLGRFRPAPgdamrsaraslplladVPPGAPLAVCVGRLSRQKG 222
Cdd:cd05844   140 lqrpAALFVAVSGFIRDRLLARGLPAeRIHVHYIGIDPAKFAPRD----------------PAERAPTILFVGRLVEKKG 203
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 223 QDVLLSAWRRV--RVPGARLVLVGEGPRGGELRRGAPDG--VLFAGA--ARDVRPWIHAADVLVLPSRW------EGMAL 290
Cdd:cd05844   204 CDVLIEAFRRLaaRHPTARLVIAGDGPLRPALQALAAALgrVRFLGAlpHAEVQDWMRRAEIFCLPSVTaasgdsEGLGI 283
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338278072 291 APLEAMACGRPVLLSDVNGARESLPPGHlPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGA 369
Cdd:cd05844   284 VLLEAAACGVPVVSSRHGGIPEAILDGE-TGFLVPEGDVDALADALQALLADRALADRMGGAARAFVCEQFDIRVQTAK 361
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
86-306 1.29e-23

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 100.39  E-value: 1.29e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  86 RLVRVCAPDVI--HAHSAKAGLAGRLAvrgRIPTVFQPHawsFEALEGRAAGLAEAWERFGARWSDRILCVSESERHAGQ 163
Cdd:cd03820    81 KYLKNNKPDVVisFRTSLLTFLALIGL---KSKLIVWEH---NNYEAYNKGLRRLLLRRLLYKRADKIVVLTEADKLKKY 154
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 164 RaGIAARWSVIHNGVDLGRFRPAPgdamrsaraslplladvPPGAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLV 241
Cdd:cd03820   155 K-QPNSNVVVIPNPLSFPSEEPST-----------------NLKSKRILAVGRLTYQKGFDLLIEAWALIakKHPDWKLR 216
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 242 LVGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSD 306
Cdd:cd03820   217 IYGDGPEREELEKlidklGLEDRVKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFD 286
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
94-377 2.29e-23

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 100.12  E-value: 2.29e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  94 DVIHAH----SAKAGLAGRLAVRGRIPTVFQPHAWSFeALEGRAAGLAEAwERFGARWSDRILCVSESER-----HAGQR 164
Cdd:cd04962    86 DVLHAHyaipHASCAYLAREILGEKIPIVTTLHGTDI-TLVGYDPSLQPA-VRFSINKSDRVTAVSSSLRqetyeLFDVD 163
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 165 AGIaarwSVIHNGVDLGRFRPAPGDAMRSARAslplladVPPGAPLAVCVGRLSRQKGQDVLLSAWRRVR--VPgARLVL 242
Cdd:cd04962   164 KDI----EVIHNFIDEDVFKRKPAGALKRRLL-------APPDEKVVIHVSNFRPVKRIDDVVRVFARVRrkIP-AKLLL 231
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 243 VGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPG 317
Cdd:cd04962   232 VGDGPERVPAEElarelGVEDRVLFLGKQDDVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGGIPEVVKHG 311
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 318 hLPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLYQEL 377
Cdd:cd04962   312 -ETGFLSDVGDVDAMAKSALSILEDDELYNRMGRAARKRAAERFDPERIVPQYEAYYRRL 370
stp2 TIGR03088
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ...
168-378 2.85e-23

sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.


Pssm-ID: 132132 [Multi-domain]  Cd Length: 374  Bit Score: 99.80  E-value: 2.85e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 168 AARWSVIHNGVDLGRFRPAPGDamRSARASLPLLADVPPgapLAVCVGRLSRQKGQDVLLSAW------RRVRVPGARLV 241
Cdd:TIGR03088 159 PAKIHQIYNGVDTERFHPSRGD--RSPILPPDFFADESV---VVGTVGRLQAVKDQPTLVRAFallvrqLPEGAERLRLV 233
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 242 LVGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPP 316
Cdd:TIGR03088 234 IVGDGPARGACEQmvraaGLAHLVWLPGERDDVPALMQALDLFVLPSLAEGISNTILEAMASGLPVIATAVGGNPELVQH 313
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338278072 317 GhLPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLYQELV 378
Cdd:TIGR03088 314 G-VTGALVPPGDAVALARALQPYVSDPAARRAHGAAGRARAEQQFSINAMVAAYAGLYDQLL 374
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
13-353 4.33e-22

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 96.64  E-value: 4.33e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  13 TVLHLVQ---PVEGGVARVVTDLVAAQVRAGLRPVVACPPGGGLAEGAAEAGA---------RVWAWPAERV-PGPRLAR 79
Cdd:cd03794     1 KILLISQyypPPKGAAAARVYELAKELVRRGHEVTVLTPSPNYPLGRIFAGATetkdgirviRVKLGPIKKNgLIRRLLN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  80 EV-----AAAGRLVRVCAPDVIHAHSA---KAGLAGRLAVRGRIPTVFQPHAW---SFEALEGRAAGLAEAW----ERFG 144
Cdd:cd03794    81 YLsfalaALLKLLVREERPDVIIAYSPpitLGLAALLLKKLRGAPFILDVRDLwpeSLIALGVLKKGSLLKLlkklERKL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 145 ARWSDRILCVSES-ERHAGQRAGIAARWSVIHNGVDLGRFRPAPGDAMRSARaslplladvPPGAPL-AVCVGRLSRQKG 222
Cdd:cd03794   161 YRLADAIIVLSPGlKEYLLRKGVPKEKIIVIPNWADLEEFKPPPKDELRKKL---------GLDDKFvVVYAGNIGKAQG 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 223 QDVLLSAWRRVR-VPGARLVLVGEGPRGGELRRGA----PDGVLFAGA--ARDVRPWIHAADVLVL------------PS 283
Cdd:cd03794   232 LETLLEAAERLKrRPDIRFLFVGDGDEKERLKELAkargLDNVTFLGRvpKEEVPELLSAADVGLVplkdnpanrgssPS 311
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338278072 284 RWegmalapLEAMACGRPVLLSDVNGARESL---PPGhlphCLVPPEDPAALASALTALLGDAGLRAELGSAA 353
Cdd:cd03794   312 KL-------FEYMAAGKPILASDDGGSDLAVeinGCG----LVVEPGDPEALADAILELLDDPELRRAMGENG 373
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
23-307 1.52e-21

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 94.74  E-value: 1.52e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  23 GGVARVVTDLVAA-QVRAGLRPVVACPPGGGLAEGAAEAGARVWAWPAERVPGPRLAREVAAAGRLVRVCAPDVIHAHSa 101
Cdd:cd03809    14 TGIGRYTRELLKAlAKNDPDESVLAVPPLPGELLRLLREYPELSLGVIKIKLWRELALLRWLQILLPKKDKPDLLHSPH- 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 102 kaGLAGRLavRGRIPTVFQPH-AWSFEALEGRAAGLAEAWERF---GARWSDRILCVSESERHAGQR-AGIAARW-SVIH 175
Cdd:cd03809    93 --NTAPLL--LKGCPQVVTIHdLIPLRYPEFFPKRFRLYYRLLlpiSLRRADAIITVSEATRDDIIKfYGVPPEKiVVIP 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 176 NGVDLgRFRPAPGDAMRSARASLPlladvppgAPLAVCVGRLSRQKGQDVLLSAWRRVR--VPGARLVLVG------EGP 247
Cdd:cd03809   169 LGVDP-SFFPPESAAVLIAKYLLP--------EPYFLYVGTLEPRKNHERLLKAFALLKkqGGDLKLVIVGgkgwedEEL 239
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338278072 248 RGGELRRGAPDGVLFAG--AARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDV 307
Cdd:cd03809   240 LDLVKKLGLGGRVRFLGyvSDEDLPALYRGARAFVFPSLYEGFGLPVLEAMACGTPVIASNI 301
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
12-306 1.60e-21

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 94.74  E-value: 1.60e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  12 LTVLHLVQPVEGGVARVVTDLVAAQVRAGLRPVVAC---PPGGGLAEGAAEAGARVWAWPAERVPGPRLAREVAAAGRLV 88
Cdd:cd03821     3 LHVTPSISPKAGGPVKVVLRLAAALAALGHEVTIVStgdGYESLVVEENGRYIPPQDGFASIPLLRQGAGRTDFSPGLPN 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  89 RVCA----PDVIHAH---SAKAGLAGRLAVRGRIPTVFQPHAwsfeALEGRAAGLAE-----AWERFGARWSDRILCV-- 154
Cdd:cd03821    83 WLRRnlreYDVVHIHgvwTYTSLAACKLARRRGIPYVVSPHG----MLDPWALQQKHwkkriALHLIERRNLNNAALVhf 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 155 -SESERHAGQRAGIAARWSVIHNGVDLGRFRPAPGDAMRSAraslplladVPPGAPLAVCVGRLSRQKGQDVLLSAWRRV 233
Cdd:cd03821   159 tSEQEADELRRFGLEPPIAVIPNGVDIPEFDPGLRDRRKHN---------GLEDRRIILFLGRIHPKKGLDLLIRAARKL 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 234 --RVPGARLVLVGEGPRGGELRR------GAPDGVLFAGAARDVRPWI--HAADVLVLPSRWEGMALAPLEAMACGRPVL 303
Cdd:cd03821   230 aeQGRDWHLVIAGPDDGAYPAFLqlqsslGLGDRVTFTGPLYGEAKWAlyASADLFVLPSYSENFGNVVAEALACGLPVV 309

                  ...
gi 1338278072 304 LSD 306
Cdd:cd03821   310 ITD 312
GT4_CapH-like cd03812
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ...
146-307 5.64e-20

capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).


Pssm-ID: 340840 [Multi-domain]  Cd Length: 357  Bit Score: 90.04  E-value: 5.64e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 146 RWSDRILCVSEserhagqragIAARW----------SVIHNGVDLGRFrpAPGDAMRSARASLPLLADvppgaPLAVC-V 214
Cdd:cd03812   135 RLSTKYLACSE----------DAGEWlfgevengkfKVIPNGIDIEKY--KFNKEKRRKRRKLLILED-----KLVLGhV 197
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 215 GRLSRQKGQDVLLS--AWRRVRVPGARLVLVGEGPRGGELR-----RGAPDGVLFAGAARDVRPWIHAADVLVLPSRWEG 287
Cdd:cd03812   198 GRFNEQKNHSFLIDifEELKKKNPNVKLVLVGEGELKEKIKekvkeLGLEDKVIFLGFRNDVSEILSAMDVFLFPSLYEG 277
                         170       180
                  ....*....|....*....|
gi 1338278072 288 MALAPLEAMACGRPVLLSDV 307
Cdd:cd03812   278 LPLVAVEAQASGLPCLLSDT 297
Glyco_transf_4 pfam13439
Glycosyltransferase Family 4;
23-180 1.05e-19

Glycosyltransferase Family 4;


Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 85.28  E-value: 1.05e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  23 GGVARVVTDLVAAQVRAGLRPVVACPPGGGLAEGAAEAGARVWAWPAERVPGPRLA-REVAAAGRLVRVCAPDVIHAHSA 101
Cdd:pfam13439   1 GGVERYVLELARALARRGHEVTVVTPGGPGPLAEEVVRVVRVPRVPLPLPPRLLRSlAFLRRLRRLLRRERPDVVHAHSP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 102 KAGLAGRLAVR--GRIPTVFQPHA-----WSFEALEGRAAGLAEAWERFGARWSDRILCVSESER-HAGQRAGI-AARWS 172
Cdd:pfam13439  81 FPLGLAALAARlrLGIPLVVTYHGlfpdyKRLGARLSPLRRLLRRLERRLLRRADRVIAVSEAVAdELRRLYGVpPEKIR 160

                  ....*...
gi 1338278072 173 VIHNGVDL 180
Cdd:pfam13439 161 VIPNGVDL 168
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
174-329 1.52e-19

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 89.04  E-value: 1.52e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 174 IHNGVDLGRFRPAPgDAMRSARASLPLLADvppgAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLVLVGEGPRGGE 251
Cdd:cd04951   159 VYNGIDLNKFKKDI-NVRLKIRNKLNLKND----EFVILNVGRLTEAKDYPNLLLAISELilSKNDFKLLIAGDGPLRNE 233
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 252 LRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLphcLVPP 326
Cdd:cd04951   234 LERlicnlNLVDRVILLGQISNISEYYNAADLFVLSSEWEGFGLVVAEAMACERPVVATDAGGVAEVVGDHNY---VVPV 310

                  ...
gi 1338278072 327 EDP 329
Cdd:cd04951   311 SDP 313
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
272-379 1.02e-18

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 81.19  E-value: 1.02e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 272 WIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLPhCLVPPEDPAALASALTALLGDAGLRAELGS 351
Cdd:COG0438    17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETG-LLVPPGDPEALAEAILRLLEDPELRRRLGE 95
                          90       100
                  ....*....|....*....|....*...
gi 1338278072 352 AAGAHARSVFDLTRTSGAVLRLYQELVG 379
Cdd:COG0438    96 AARERAEERFSWEAIAERLLALYEELLA 123
Glyco_trans_4_4 pfam13579
Glycosyl transferase 4-like domain;
23-177 3.23e-18

Glycosyl transferase 4-like domain;


Pssm-ID: 433325 [Multi-domain]  Cd Length: 158  Bit Score: 80.91  E-value: 3.23e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  23 GGVARVVTDLVAAQVRAGLRPVVACPPGGGLAEGAAEAGARVWAWPAERVPGPRLA-REVAAAGRLVRVCAPDVIHAHSA 101
Cdd:pfam13579   1 GGIGVYVLELARALAALGHEVRVVTPGGPPGRPELVGDGVRVHRLPVPPRPSPLADlAALRRLRRLLRAERPDVVHAHSP 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338278072 102 KAGLAGRLA-VRGRIPTVFQPHAWSFEALEGRAAGLAEAWERFGARWSDRILCVSESERHAGQRAGI-AARWSVIHNG 177
Cdd:pfam13579  81 TAGLAARLArRRRGVPLVVTVHGLALDYGSGWKRRLARALERRLLRRADAVVVVSEAEAELLRALGVpAARVVVVPNG 158
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
211-318 1.03e-17

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 81.68  E-value: 1.03e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 211 AVCVGRLSRQKGQDVLLSAWRRV--RVPGARLVLVGEGPRG-------GELRRGAPDGVLFAGAARDVRPWIHA-ADVLV 280
Cdd:cd01635   113 KVSVGRLVPEKGIDLLLEALALLkaRLPDLVLVLVGGGGEReeeealaAALGLLERVVIIGGLVDDEVLELLLAaADVFV 192
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1338278072 281 LPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGH 318
Cdd:cd01635   193 LPSRSEGFGLVLLEAMAAGKPVIATDVGGIPEFVVDGE 230
MSMEG_0565_glyc TIGR04047
glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from ...
94-376 4.11e-17

glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from Actinobacteria to Proteobacteria to Cyanobacteria features a radical SAM protein, an N-acetyltransferase, an oxidoreductase, and two additional proteins whose functional classes are unclear. The metabolic role of the cluster is probably biosynthetic. This glycosyltransferase, named from member MSMEG_0565 from Mycobacterium smegmatis, occurs in most but not all instances of the cluster. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 274943 [Multi-domain]  Cd Length: 373  Bit Score: 82.06  E-value: 4.11e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  94 DVIHAHSAKAGLA-GRLAVRGRIPTVFQphawSFEALEGRAAGLAEAWERFGARWSDRILCVSESERhAGQRAGIAARWS 172
Cdd:TIGR04047  88 DVVHAQDCISGNAlATLRAEGLIPGFVR----TVHHLDDFDDPRLAACQERAIVEADAVLCVSAAWA-AELRAEWGIDAT 162
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 173 VIHNGVDLGRFRPAPGDAMRSARASLPLladvpPGAPLAVCVGRLSRQKGQDVLLSAWRRVR--VPGARLVLVG------ 244
Cdd:TIGR04047 163 VVPNGVDAARFSPAADAADAALRRRLGL-----RGGPYVLAVGGIEPRKNTIDLLEAFALLRarRPQAQLVIAGgatlfd 237
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 245 -EGPRGGELRRGA-----PDGVLFAGAARD--VRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLpp 316
Cdd:TIGR04047 238 yDAYRREFRARAAelgvdPGPVVITGPVPDadLPALYRCADAFAFPSLKEGFGLVVLEALASGIPVVASDIAPFTEYL-- 315
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 317 GHLPHCLVPPEDPAALASALTALLGDAGlRAELGSAAGAHARSvFDLTRTSGAVLRLYQE 376
Cdd:TIGR04047 316 GRFDAAWADPSDPDSIADALALALDPAR-RPALRAAGPELAAR-YTWDASARAHLEFYRR 373
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
12-329 1.17e-16

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 80.45  E-value: 1.17e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  12 LTVLHLVQPVE-GGVARVVTDLVAAQVRAGLRPVVACP---PGGGLAEGAAEAGARVWAWPAERVPG------------P 75
Cdd:cd03823     3 LLVNSLYPPQRvGGAEISVHDLAEALVAEGHEVAVLTAgvgPPGQATVARSVVRYRRAPDETLPLALkrrgyelfetynP 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  76 RLAREVAAAGRLVRvcaPDVIHAHS---AKAGLAGRLAVRGrIPTVFQPHawSFEALEGRAaglaeawERFGARwSDRIL 152
Cdd:cd03823    83 GLRRLLARLLEDFR---PDVVHTHNlsgLGASLLDAARDLG-IPVVHTLH--DYWLLCPRQ-------FLFKKG-GDAVL 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 153 CVSESERHAGQRAGI-AARWSVIHNGVDLGRfrpapgdamrsarasLPLLADVPPGAPLAVC-VGRLSRQKGQDVLLSAW 230
Cdd:cd03823   149 APSRFTANLHEANGLfSARISVIPNAVEPDL---------------APPPRRRPGTERLRFGyIGRLTEEKGIDLLVEAF 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 231 RRVRVPGARLVLVGEGPRGGELRRGAPDGVLFAGAARDVRPWIH--AADVLVLPSRW-EGMALAPLEAMACGRPVLLSDV 307
Cdd:cd03823   214 KRLPREDIELVIAGHGPLSDERQIEGGRRIAFLGRVPTDDIKDFyeKIDVLVVPSIWpEPFGLVVREAIAAGLPVIASDL 293
                         330       340
                  ....*....|....*....|..
gi 1338278072 308 NGARESLPPGHLPHcLVPPEDP 329
Cdd:cd03823   294 GGIAELIQPGVNGL-LFAPGDA 314
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
75-353 4.21e-16

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 79.37  E-value: 4.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  75 PRLAREVAAAgrlvrvcAPDVIHAHSAKAGLAGRLAVRG--RIPTV--FQPHAWSFEALEGRAAGLAEAWE--RFGARWS 148
Cdd:PLN02871  134 PRIISEVARF-------KPDLIHASSPGIMVFGALFYAKllCVPLVmsYHTHVPVYIPRYTFSWLVKPMWDiiRFLHRAA 206
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 149 DRILCVSE--SERHAGQRAGIAARWSVIHNGVDLGRFRPA-PGDAMRSAraslplLADVPPGAPLAVCVGRLSRQKGQDV 225
Cdd:PLN02871  207 DLTLVTSPalGKELEAAGVTAANRIRVWNKGVDSESFHPRfRSEEMRAR------LSGGEPEKPLIVYVGRLGAEKNLDF 280
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 226 LlsawRRV--RVPGARLVLVGEGPRGGELRR---GAPdgVLFAGAAR--DVRPWIHAADVLVLPSRWEGMALAPLEAMAC 298
Cdd:PLN02871  281 L----KRVmeRLPGARLAFVGDGPYREELEKmfaGTP--TVFTGMLQgdELSQAYASGDVFVMPSESETLGFVVLEAMAS 354
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1338278072 299 GRPVLLSDVNGARESLPPGHLPHC--LVPPEDPAALASALTALLGDAGLRAELGSAA 353
Cdd:PLN02871  355 GVPVVAARAGGIPDIIPPDQEGKTgfLYTPGDVDDCVEKLETLLADPELRERMGAAA 411
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
153-377 4.91e-14

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 72.75  E-value: 4.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 153 CVSESERHAGQRAgiaarwSVIHNGVDLGRFRPAPgdaMRSARASLPLLADVPpgAPLAVCVGRLSRQKGQDVLLSAWRR 232
Cdd:cd03825   151 MVRRSPLLKGLPV------VVIPNGIDTEIFAPVD---KAKARKRLGIPQDKK--VILFGAESVTKPRKGFDELIEALKL 219
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 233 -VRVPGARLVLVGEGPrggELRRGAPDGVLFAGAARDV---RPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVN 308
Cdd:cd03825   220 lATKDDLLLVVFGKND---PQIVILPFDIISLGYIDDDeqlVDIYSAADLFVHPSLADNLPNTLLEAMACGTPVVAFDTG 296
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338278072 309 GARESLPPGHLPHcLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLYQEL 377
Cdd:cd03825   297 GSPEIVQHGVTGY-LVPPGDVQALAEAIEWLLANPKERESLGERARALAENHFDQRVQAQRYLELYKDL 364
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
94-374 4.91e-13

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 70.06  E-value: 4.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  94 DVIHAHSAK-AGLAGRLAVRGR-IPTVFQPHA--------------WSFEALEGRaagLAEAWERFGA---RWSDRILCV 154
Cdd:cd03813   175 DLYHSVSTGyAGLLGALARHRRgIPFLLTEHGiytrerkieilqstWIMGYIKKL---WIRFFERLGKlayQQADKIISL 251
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 155 SESERHAGQRAGI-AARWSVIHNGVDLGRFRPApgdamrsaraslplLADVPPGAPLAV-CVGRLSRQKGQDVLLSAWRR 232
Cdd:cd03813   252 YEGNRRRQIRLGAdPDKTRVIPNGIDIQRFAPA--------------REERPEKEPPVVgLVGRVVPIKDVKTFIRAFKL 317
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 233 VR--VPGARLVLVG---EGPR-GGELRRGAP-----DGVLFAGAARdVRPWIHAADVLVLPSRWEGMALAPLEAMACGRP 301
Cdd:cd03813   318 VRraMPDAEGWLIGpedEDPEyAQECKRLVAslgleNKVKFLGFQN-IKEYYPKLGLLVLTSISEGQPLVILEAMASGVP 396
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338278072 302 VLLSDVNGARESLPPGHLPHC----LVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTRTSGAVLRLY 374
Cdd:cd03813   397 VVATDVGSCRELIYGADDALGqaglVVPPADPEALAEALIKLLRDPELRQAFGEAGRKRVEKYYTLEGMIDSYRKLY 473
PRK10307 PRK10307
colanic acid biosynthesis glycosyltransferase WcaI;
131-362 9.69e-12

colanic acid biosynthesis glycosyltransferase WcaI;


Pssm-ID: 236670 [Multi-domain]  Cd Length: 412  Bit Score: 66.15  E-value: 9.69e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 131 GRAAGLAEAWERFGARWSDRILCVSESE-RHAGQRAGIAARWSVIHNGVDLGRFRPAPGDAMRSARASLpllaDVPPGAP 209
Cdd:PRK10307  155 GKVARLATAFERSLLRRFDNVSTISRSMmNKAREKGVAAEKVIFFPNWSEVARFQPVADADVDALRAQL----GLPDGKK 230
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 210 LAVCVGRLSRQKGQDVLLSAWRRVRV-PGARLVLVGEGPRGGELRRGAPDGVLFAGAARDVRPW-----------IH--- 274
Cdd:PRK10307  231 IVLYSGNIGEKQGLELVIDAARRLRDrPDLIFVICGQGGGKARLEKMAQCRGLPNVHFLPLQPYdrlpallkmadCHllp 310
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 275 ----AADvLVLPSRWEGMalapleaMACGRPVllsdVNGARESLPPGHLphC-----LVPPEDPAALASALTALLGDAGL 345
Cdd:PRK10307  311 qkagAAD-LVLPSKLTNM-------LASGRNV----VATAEPGTELGQL--VegigvCVEPESVEALVAAIAALARQALL 376
                         250
                  ....*....|....*..
gi 1338278072 346 RAELGSAAGAHARSVFD 362
Cdd:PRK10307  377 RPKLGTVAREYAERTLD 393
glgA TIGR02095
glycogen/starch synthase, ADP-glucose type; This family consists of glycogen (or starch) ...
93-313 3.18e-11

glycogen/starch synthase, ADP-glucose type; This family consists of glycogen (or starch) synthases that use ADP-glucose (EC 2.4.1.21), rather than UDP-glucose (EC 2.4.1.11) as in animals, as the glucose donor. This enzyme is found in bacteria and plants. Whether the name given is glycogen synthase or starch synthase depends on context, and therefore on substrate. [Energy metabolism, Biosynthesis and degradation of polysaccharides]


Pssm-ID: 273969 [Multi-domain]  Cd Length: 473  Bit Score: 64.59  E-value: 3.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  93 PDVIHAHSAKAGLAGRLA----VRGRIPTVFQPHAWSFEAL--EGRAAGLAEAWERF----------------GARWSDR 150
Cdd:TIGR02095 129 PDVVHAHDWHTALVPALLkavyRPNPIKTVFTIHNLAYQGVfpADDFSELGLPPEYFhmeglefygrvnflkgGIVYADR 208
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 151 ILCVSE--------SERHAGQRAGIAARWSVIH---NGVDLGRFRPAPgDAMRSARASLPLLA---------------DV 204
Cdd:TIGR02095 209 VTTVSPtyareiltPEFGYGLDGVLKARSGKLRgilNGIDTEVWNPAT-DPYLKANYSADDLAgkaenkealqeelglPV 287
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 205 PPGAPLAVCVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPRG--GELRRGA---PDGV-LFAGAARDVRPWIHA-AD 277
Cdd:TIGR02095 288 DDDVPLFGVISRLTQQKGVDLLLAALPELLELGGQLVVLGTGDPEleEALRELAeryPGNVrVIIGYDEALAHLIYAgAD 367
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1338278072 278 VLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARES 313
Cdd:TIGR02095 368 FILMPSRFEPCGLTQLYAMRYGTVPIVRRTGGLADT 403
GT5_Glycogen_synthase_DULL1-like cd03791
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ...
93-296 3.35e-11

Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.


Pssm-ID: 340822 [Multi-domain]  Cd Length: 474  Bit Score: 64.51  E-value: 3.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  93 PDVIHAHSAKAGLA-------GRLAVRGRIPTVFQPH------AWSFEALEgraaGLAEAWERF---------------- 143
Cdd:cd03791   129 PDIIHANDWHTALVpaylktrYRGPGFKKIKTVFTIHnlayqgLFPLDTLA----ELGLPPELFhidglefygqinflka 204
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 144 GARWSDRILCVSES-----------ERHAGQRAGIAARWSVIHNGVDLGRFRPApGDAMRSARASLPLLAD--------- 203
Cdd:cd03791   205 GIVYADRVTTVSPTyakeiltpeygEGLDGVLRARAGKLSGILNGIDYDEWNPA-TDKLIPANYSANDLEGkaenkaalq 283
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 204 ------VPPGAPLAVCVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPRGGElrrgapdGVLFAGAAR---DVRPWI- 273
Cdd:cd03791   284 kelglpVDPDAPLFGFVGRLTEQKGVDLILDALPELLEEGGQLVVLGSGDPEYE-------QAFRELAERypgKVAVVIg 356
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1338278072 274 ------H----AADVLVLPSRWEGMALAPLEAM 296
Cdd:cd03791   357 fdealaHriyaGADFFLMPSRFEPCGLVQMYAM 389
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
214-365 7.39e-11

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 63.06  E-value: 7.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 214 VGRLSRQKGQDVLLSAWRRVRVPgarLVLVGEGPRGGELRRGAP----DGVLFAGAARDVRPWI--HAADVLVLPSRW-- 285
Cdd:cd03795   197 IGRLVYYKGLDYLIEAAQYLNYP---IVIGGEGPLKPDLEAQIElnllDNVKFLGRVDDEEKVIylHLCDVFVFPSVLrs 273
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 286 EGMALAPLEAMACGRPVLLSDVNGARESLPPGHLPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTR 365
Cdd:cd03795   274 EAFGIVLLEAMMCGKPVISTNIGTGVPYVNNNGETGLVVPPKDPDALAEAIDKLLSDEELRESYGENAKKRFEELFTAEK 353
GT4_WbaZ-like cd03804
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ...
172-317 6.28e-10

mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.


Pssm-ID: 340833 [Multi-domain]  Cd Length: 356  Bit Score: 59.99  E-value: 6.28e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 172 SVIHNGVDLGRFRPAPgdamrsaraslplladvpPGAPLAVCVGRLSRQKGQDVLLSAWRRVrvpGARLVLVGEGPRGGE 251
Cdd:cd03804   181 TVIYPPVDTDAFAPAA------------------DKEDYYLTASRLVPYKRIDLAVEAFNEL---PKRLVVIGDGPDLDR 239
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338278072 252 LRRGAPDGVLFAGAARD--VRPWIHAADVLVLPSRwEGMALAPLEAMACGRPVLLSDVNGARESLPPG 317
Cdd:cd03804   240 LRAMASPNVEFLGYQPDevLKELLSKARAFVFAAE-EDFGIVPVEAQACGTPVIAFGKGGALETVRPG 306
PRK14099 PRK14099
glycogen synthase GlgA;
67-309 9.65e-10

glycogen synthase GlgA;


Pssm-ID: 237610 [Multi-domain]  Cd Length: 485  Bit Score: 60.12  E-value: 9.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  67 WPAERVPGPRLAREVAAAGR-LVRVCAPDVIHAHSAKAGLAG---RLAVRGRIPTVFQPHAWSFEA-----------LEG 131
Cdd:PRK14099  107 WPDNAQRFAALARAAAAIGQgLVPGFVPDIVHAHDWQAGLAPaylHYSGRPAPGTVFTIHNLAFQGqfprellgalgLPP 186
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 132 RAAGLaEAWERFGA--------RWSDRILCVSES--ERHAGQRAGI---------AARWSVIHNGVDLGRFRPApGDAMR 192
Cdd:PRK14099  187 SAFSL-DGVEYYGGigylkaglQLADRITTVSPTyaLEIQGPEAGMgldgllrqrADRLSGILNGIDTAVWNPA-TDELI 264
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 193 SARASLPLLA---------------DVPPGAPLAVCVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPRggELRRGAP 257
Cdd:PRK14099  265 AATYDVETLAaraankaalqarfglDPDPDALLLGVISRLSWQKGLDLLLEALPTLLGEGAQLALLGSGDA--ELEARFR 342
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338278072 258 DGVL--------FAGAARDVRPWIHA-ADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNG 309
Cdd:PRK14099  343 AAAQaypgqigvVIGYDEALAHLIQAgADALLVPSRFEPCGLTQLCALRYGAVPVVARVGG 403
GT4_PIG-A-like cd03796
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ...
94-328 1.01e-09

phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.


Pssm-ID: 340827 [Multi-domain]  Cd Length: 398  Bit Score: 59.56  E-value: 1.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  94 DVIHAHSAKAGLAGRLAVRGR---IPTVFQPHawSFEALEGRAAGLAEAWERFGARWSDRILCVSeserHAGQ-----RA 165
Cdd:cd03796    90 QIVHGHQAFSSLAHEALFHARtlgLKTVFTDH--SLFGFADASSILTNKLLRFSLADIDHVICVS----HTSKentvlRA 163
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 166 GIA-ARWSVIHNGVDLGRFRPAPGDAmrsaraslplladvPPGAPLAVCVGRLSRQKGQDVLLSAWRRV--RVPGARLVL 242
Cdd:cd03796   164 SLDpRIVSVIPNAVDSSDFTPDPSKP--------------DPNKITIVVISRLVYRKGIDLLVGIIPRIckKHPNVRFII 229
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 243 VGEGPRGGEL-----RRGAPDGVLFAGAAR--DVRpwihaaDVLVL------PSRWEGMALAPLEAMACGRPVLLSDVNG 309
Cdd:cd03796   230 GGDGPKRIELeemreKYQLQDRVELLGAVPheEVR------DVLVQghiflnTSLTEAFCIAIVEAASCGLLVVSTRVGG 303
                         250
                  ....*....|....*....
gi 1338278072 310 ARESLPPGHLPHCLVPPED 328
Cdd:cd03796   304 IPEVLPPDMILLAEPDPED 322
GlgA COG0297
Glycogen synthase [Carbohydrate transport and metabolism];
77-286 4.88e-08

Glycogen synthase [Carbohydrate transport and metabolism];


Pssm-ID: 440066 [Multi-domain]  Cd Length: 476  Bit Score: 54.71  E-value: 4.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  77 LAREVAAAGRLVRVcAPDVIHAHSAKAGLA-------GRLAVRGRIPTVF-------Q--------------PHAWSFEA 128
Cdd:COG0297   115 FSRAALELLKGLDW-KPDIIHCHDWQTGLIpallktrYADDPFKRIKTVFtihnlayQgifpaeilellglpPELFTPDG 193
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 129 LE--GR----AAGLaeawerfgaRWSDRILCVSES------------------ERHAGQRAGIAarwsvihNGVDLGRFR 184
Cdd:COG0297   194 LEfyGQinflKAGI---------VYADRVTTVSPTyareiqtpefgegldgllRARSGKLSGIL-------NGIDYDVWN 257
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 185 PApGDAMRSARASLPLLA---------------DVPPGAPLAVCVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPRG 249
Cdd:COG0297   258 PA-TDPYLPANYSADDLEgkaankaalqeelglPVDPDAPLIGMVSRLTEQKGLDLLLEALDELLEEDVQLVVLGSGDPE 336
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1338278072 250 -----GELRRGAPDGV-------------LFAGaardvrpwihaADVLVLPSRWE 286
Cdd:COG0297   337 yeeafRELAARYPGRVavyigydealahrIYAG-----------ADFFLMPSRFE 380
GT4_ExpC-like cd03818
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ...
170-365 7.00e-08

Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).


Pssm-ID: 340845 [Multi-domain]  Cd Length: 396  Bit Score: 53.91  E-value: 7.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 170 RWSVIHNGVDLGRFRPAPgdamrSARASLPLLADVPPGAPLAVCVGR-LSRQKGQDVLLSAWRRV--RVPGARLVLVG-- 244
Cdd:cd03818   180 RISVIHDGVDTDRLAPDP-----AARLRLLNGTELKAGDPVITYVARnLEPYRGFHVFMRALPRIqaRRPDARVVVVGgd 254
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 245 ------EGPRGGELR-------RGAPDGVLFAG-AARDV-RPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNG 309
Cdd:cd03818   255 gvsygsPPPDGGSWKqkmlaelGVDLERVHFVGkVPYDQyVRLLQLSDAHVYLTYPFVLSWSLLEAMACGCPVIGSDTAP 334
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1338278072 310 ARESLPPGHlPHCLVPPEDPAALASALTALLGDAGLRAELGSAAGAHARSVFDLTR 365
Cdd:cd03818   335 VREVIRDGR-NGLLVDFFDPDALAAAVLELLEDPDRAAALRRAARRTVERSDSLDV 389
PRK15490 PRK15490
Vi polysaccharide biosynthesis glycosyltransferase TviE;
236-317 1.25e-07

Vi polysaccharide biosynthesis glycosyltransferase TviE;


Pssm-ID: 185387 [Multi-domain]  Cd Length: 578  Bit Score: 53.55  E-value: 1.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 236 PGARLVLVGEGPRGGELRR-----GAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGA 310
Cdd:PRK15490  428 PATRFVLVGDGDLRAEAQKraeqlGILERILFVGASRDVGYWLQKMNVFILFSRYEGLPNVLIEAQMVGVPVISTPAGGS 507

                  ....*..
gi 1338278072 311 RESLPPG 317
Cdd:PRK15490  508 AECFIEG 514
GT4_AviGT4-like cd03802
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ...
23-303 4.52e-07

UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.


Pssm-ID: 340832 [Multi-domain]  Cd Length: 333  Bit Score: 51.13  E-value: 4.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  23 GGVARVVTDLVAAQVRAG-------------LRPVVACPPggglaegaaeagarVWAWPAERVPGPRLAREVAAAGRLVR 89
Cdd:cd03802    18 GGTELVVSALTEGLVRRGhevtlfapgdshtSAPLVAVIP--------------RALRLDPIPQESKLAELLEALEVQLR 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  90 VCAPDVIHAHSAkaGLAGRLAVRGRIPTVfqphawsfEALEGRAagLAEAWERFGARWSDRILCVSeserHAGQRAGIAA 169
Cdd:cd03802    84 ASDFDVIHNHSY--DWLPPFAPLIGTPFV--------TTLHGPS--IPPSLAIYAAEPPVNYVSIS----DAQRAATPPI 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 170 RW-SVIHNGVDLGRFRPAPgdamrsaraslplladvPPGAPLAVcVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPR 248
Cdd:cd03802   148 DYlTVVHNGLDPADYRFQP-----------------DPEDYLAF-LGRIAPEKGLEDAIRVARRAGLPLKIAGKVRDEDY 209
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1338278072 249 GGELRRGAP-DGVLFAGAARDVR--PWIHAADVLVLPSRW-EGMALAPLEAMACGRPVL 303
Cdd:cd03802   210 FYYLQEPLPgPRIEFIGEVGHDEkqELLGGARALLFPINWdEPFGLVMIEAMACGTPVI 268
GT4_mannosyltransferase-like cd03822
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ...
141-329 9.30e-06

mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.


Pssm-ID: 340849 [Multi-domain]  Cd Length: 370  Bit Score: 47.38  E-value: 9.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 141 ERFGARWSDRILCVSESERHAGQRAGI-AARWSVIHNGVdlgrFRPAPGDAMRSARASLPLladvppGAPLAVCVGRLSR 219
Cdd:cd03822   129 FRIATLSERVVVMAPISRFLLVRIKLIpAVNIEVIPHGV----PEVPQDPTTALKRLLLPE------GKKVILTFGFIGP 198
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 220 QKGQDVLLSAWRRVR--VPGARLVLVGEgpRGGELRRGAPDGVLFAGAAR-----------------DVRPWIHAADVLV 280
Cdd:cd03822   199 GKGLEILLEALPELKaeFPDVRLVIAGE--LHPSLARYEGERYRKAAIEElglqdhvdfhnnflpeeEVPRYISAADVVV 276
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1338278072 281 LP--SRWEGMALAPLEAMACGRPVLLSDVNGAREslppghLPHC----LVPPEDP 329
Cdd:cd03822   277 LPylNTEQSSSGTLSYAIACGKPVISTPLRHAEE------LLADgrgvLVPFDDP 325
Glyco4_Geo_Pelo NF038229
GPMC system family 4 glycosyltransferase; Members of this family are family 4 ...
274-379 1.10e-05

GPMC system family 4 glycosyltransferase; Members of this family are family 4 glycosyltransferases of the GPMC (Geobacter/Pelobacter Mystery Cassette) system, in which the most distinctive signature is the TIGR04442 protein family.


Pssm-ID: 439530 [Multi-domain]  Cd Length: 338  Bit Score: 46.90  E-value: 1.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 274 HAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGAREslppghlphcLVPPE-------DPAALASALTALLGDAGLR 346
Cdd:NF038229  236 RRADVVLNNSLFEGMANALLEAMALGRPVLARDIPGNRS----------VVRPGvtgllyrDEAEFLRQARQLLQDPALR 305
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1338278072 347 AELGSAAGAHARSVFDLTRTSGAVLRLYQELVG 379
Cdd:NF038229  306 RRLGRPGRQLVRERYSPEREAEAYLRLYRAVLA 338
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
234-375 3.97e-05

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 45.80  E-value: 3.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 234 RVPGARLVLVGEGP-----RGGELRRGAPDGVLFAGAARDVRPWIHAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVN 308
Cdd:PRK15179  545 SHPKVRFIMVGGGPllesvREFAQRLGMGERILFTGLSRRVGYWLTQFNAFLLLSRFEGLPNVLIEAQFSGVPVVTTLAG 624
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338278072 309 GARESLPPGHLPHCLVP-----PEDPAALASALTALLGDAGLRAElgsaAGAHARSVFDLTRTSGAVLRLYQ 375
Cdd:PRK15179  625 GAGEAVQEGVTGLTLPAdtvtaPDVAEALARIHDMCAADPGIARK----AADWASARFSLNQMIASTVRCYQ 692
GT4_AmsK-like cd03799
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ...
92-328 1.84e-04

Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.


Pssm-ID: 340829 [Multi-domain]  Cd Length: 350  Bit Score: 43.21  E-value: 1.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  92 APDVIHAHSAKAGLAGRLAVR-----GRIPTVFQPHAWS-FEALEGRAAglaeaWERFGARwSDRILCVSESERHAGQRA 165
Cdd:cd03799    70 AYDIIHCQFGPLGALGALLRRlkvlkGKLVTSFRGYDISmYVILEGNKV-----YPQLFAQ-GDLFLPNCELFKHRLIAL 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 166 GIAARWSVIHN-GVDLGRFRPAPgdamrsaraslpllADVPPGAPLAVC-VGRLSRQKGQDVLLSAWRRV--RVPGARLV 241
Cdd:cd03799   144 GCDEKKIIVHRsGIDCNKFRFKP--------------RYLPLDGKIRILtVGRLTEKKGLEYAIEAVAKLaqKYPNIEYQ 209
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 242 LVGEGPRGGELRRGAPDG-----VLFAGAAR--DVRPWIHAADVLVLPS------RWEGMALAPLEAMACGRPVLLSDVN 308
Cdd:cd03799   210 IIGDGDLKEQLQQLIQELnigdcVKLLGWKPqeEIIEILDEADIFIAPSvtaadgDQDGPPNTLKEAMAMGLPVISTEHG 289
                         250       260
                  ....*....|....*....|
gi 1338278072 309 GARESLPPGhLPHCLVPPED 328
Cdd:cd03799   290 GIPELVEDG-VSGFLVPERD 308
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
168-312 1.86e-04

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 43.38  E-value: 1.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 168 AARWSVIHNGVDLGRFRPApgdamRSARaslplladvPPGAPLAVC-VGRLSRQKGQDVLLSAWRRV--RVPGARLVLVG 244
Cdd:NF038011  279 PERTRVIPNGIDLPRLAPL-----RAQR---------PAGIPPVVGlIGRVVPIKDIKTFIRAMRTVvrAMPEAEGWIVG 344
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338278072 245 ---EGPRGGELRR------GAPDGVLFAGAAR--DVRPWIhaaDVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARE 312
Cdd:NF038011  345 peeEDPAYAAECRslvaslGLQDKVKFLGFQKidDLLPQV---GLMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQ 420
GT4_GtfA-like cd04949
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ...
214-312 2.49e-04

accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340855 [Multi-domain]  Cd Length: 328  Bit Score: 42.67  E-value: 2.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 214 VGRLSRQKGQDVLLSAWRRVR--VPGARLVLVGEG-----PRGGELRRGAPDGVLFAGAARDVRPWIHAADVLVLPSRWE 286
Cdd:cd04949   166 ISRLAPEKQLDHLIEAVAKAVkkVPEITLDIYGYGeerekLKKLIEELHLEDNVFLKGYHSNLDQEYQDAYLSLLTSQME 245
                          90       100
                  ....*....|....*....|....*..
gi 1338278072 287 GMALAPLEAMACGRPVLLSDVN-GARE 312
Cdd:cd04949   246 GFGLTLMEAIGHGLPVVSYDVKyGPSE 272
PRK15484 PRK15484
lipopolysaccharide N-acetylglucosaminyltransferase;
168-312 6.50e-04

lipopolysaccharide N-acetylglucosaminyltransferase;


Pssm-ID: 185381 [Multi-domain]  Cd Length: 380  Bit Score: 41.70  E-value: 6.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 168 AARWSVIHNGVDLGRFRPAPGDAMRSAraslpllADVPPGAPLAVCVGRLSRQKGQDVLLSAWRRVRV--PGARLVLVGE 245
Cdd:PRK15484  160 NADISIVPNGFCLETYQSNPQPNLRQQ-------LNISPDETVLLYAGRISPDKGILLLMQAFEKLATahSNLKLVVVGD 232
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 246 --GPRGGE-----------LRRGAPDGVLFAGAARD-VRPWIHAADVLVLPSRW-EGMALAPLEAMACGRPVLLSDVNGA 310
Cdd:PRK15484  233 ptASSKGEkaayqkkvleaAKRIGDRCIMLGGQPPEkMHNYYPLADLVVVPSQVeEAFCMVAVEAMAAGKPVLASTKGGI 312

                  ..
gi 1338278072 311 RE 312
Cdd:PRK15484  313 TE 314
glgA PRK00654
glycogen synthase GlgA;
93-299 6.87e-04

glycogen synthase GlgA;


Pssm-ID: 234809 [Multi-domain]  Cd Length: 466  Bit Score: 41.64  E-value: 6.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072  93 PDVIHAHSAKAGLA------GRLAVRGRIPTVFQPH------AWSFEALegRAAGL-AEAWERFGARW------------ 147
Cdd:PRK00654  119 PDIVHAHDWHTGLIpallkeKYWRGYPDIKTVFTIHnlayqgLFPAEIL--GELGLpAEAFHLEGLEFygqisflkagly 196
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 148 -SDRILCVSESerHA--------GQR-----AGIAARWSVIHNGVDLGRFRPApGDAMRSARASLPLLAD---------- 203
Cdd:PRK00654  197 yADRVTTVSPT--YAreittpefGYGlegllRARSGKLSGILNGIDYDIWNPE-TDPLLAANYSADDLEGkaenkralqe 273
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 204 ----VPPGAPLAVCVGRLSRQKGQDVLLSAWRRVRVPGARLVLVGEGPRG--GELRRGA---PDGVlfaGA--------A 266
Cdd:PRK00654  274 rfglPDDDAPLFAMVSRLTEQKGLDLVLEALPELLEQGGQLVLLGTGDPEleEAFRALAaryPGKV---GVqigydealA 350
                         250       260       270
                  ....*....|....*....|....*....|....
gi 1338278072 267 RdvrpWIHA-ADVLVLPSRWEGMALAPLEAMACG 299
Cdd:PRK00654  351 H----RIYAgADMFLMPSRFEPCGLTQLYALRYG 380
GT4_trehalose_phosphorylase cd03792
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ...
203-365 2.16e-03

trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.


Pssm-ID: 340823 [Multi-domain]  Cd Length: 378  Bit Score: 40.00  E-value: 2.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 203 DVPPGAPLAVCVGRLSRQKGQDVLLSAWRRVR--VPGARLVLVGEGPRGGelrrgaPDGVLF-------AGAARDvrpwI 273
Cdd:cd03792   192 VIDPERPYILQVARFDPSKDPLGVIDAYKLFKrrAEEPQLVICGHGAVDD------PEGSVVyeevmeyAGDDHD----I 261
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338278072 274 H----------------AADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARESLPPGHLPHcLVPPEDPAALASALT 337
Cdd:cd03792   262 HvlrlppsdqeinalqrAATVVLQLSTREGFGLTVSEALWKGKPVIATPAGGIPLQVIDGETGF-LVNSVEGAAVRILRL 340
                         170       180
                  ....*....|....*....|....*...
gi 1338278072 338 ALlgDAGLRAELGSAAGAHARSVFDLTR 365
Cdd:cd03792   341 LT--DPELRRKMGLAAREHVRDNFLITG 366
GT4_AmsK-like cd04946
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ...
274-312 9.09e-03

amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.


Pssm-ID: 340854 [Multi-domain]  Cd Length: 401  Bit Score: 37.82  E-value: 9.09e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1338278072 274 HAADVLVLPSRWEGMALAPLEAMACGRPVLLSDVNGARE 312
Cdd:cd04946   303 NDVDVFVNVSESEGIPVSIMEAISFGIPVIATNVGGTRE 341
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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