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Conserved domains on  [gi|1339737984|ref|WP_103621902|]
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MULTISPECIES: helix-turn-helix domain-containing protein [Bacillus cereus group]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 11443570)

helix-turn-helix domain-containing protein such as an XRE (Xenobiotic Response Element) family transcriptional regulator

Gene Ontology:  GO:0003677
PubMed:  37972151

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-79 1.69e-20

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


:

Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 78.11  E-value: 1.69e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1339737984   1 MKTFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLLGRDFDVERNRNDSELD 79
Cdd:COG1396     5 KKALGERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGADEELPEALLSEEE 83
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-79 1.69e-20

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 78.11  E-value: 1.69e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1339737984   1 MKTFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLLGRDFDVERNRNDSELD 79
Cdd:COG1396     5 KKALGERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGADEELPEALLSEEE 83
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 5-62 6.67e-16

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 65.65  E-value: 6.67e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1339737984   5 GNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFL 62
Cdd:cd00093     1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
8-62 5.34e-15

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 63.31  E-value: 5.34e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1339737984    8 IRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFL 62
Cdd:smart00530   2 LKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 8-62 9.46e-15

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 62.94  E-value: 9.46e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1339737984   8 IRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFL 62
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
PRK09706 PRK09706
transcriptional repressor DicA; Reviewed
 2-68 5.08e-07

transcriptional repressor DicA; Reviewed


Pssm-ID: 182039 [Multi-domain]  Cd Length: 135  Bit Score: 44.84  E-value: 5.08e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1339737984   2 KTFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLLGRDFD 68
Cdd:PRK09706    4 LTLGQRIRYRRKQLKLSQRSLAKAVKVSHVSISQWERDETEPTGKNLFALAKALQCSPTWLLFGDED 70
couple_hipB TIGR03070
transcriptional regulator, y4mF family; Members of this family belong to a clade of ...
 2-53 7.63e-06

transcriptional regulator, y4mF family; Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions]


Pssm-ID: 213767 [Multi-domain]  Cd Length: 58  Bit Score: 39.95  E-value: 7.63e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1339737984   2 KTFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIAD 53
Cdd:TIGR03070   1 KQIGILVRARRKALGLTQADLADLAGVGLRFIRDLENGKPTVRLDKVLRVLD 52
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-79 1.69e-20

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 78.11  E-value: 1.69e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1339737984   1 MKTFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLLGRDFDVERNRNDSELD 79
Cdd:COG1396     5 KKALGERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGADEELPEALLSEEE 83
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-66 6.95e-18

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 71.03  E-value: 6.95e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1339737984   1 MKTFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLLGRD 66
Cdd:COG1476     2 KKKLGNRLKELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELFSLE 67
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 5-62 6.67e-16

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 65.65  E-value: 6.67e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1339737984   5 GNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFL 62
Cdd:cd00093     1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
8-62 5.34e-15

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 63.31  E-value: 5.34e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1339737984    8 IRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFL 62
Cdd:smart00530   2 LKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
 3-58 5.36e-15

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 63.80  E-value: 5.36e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1339737984   3 TFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVS 58
Cdd:COG1813    12 DYGERIREAREARGLSQEELAEKLGVSESTIRRIERGEATPSLDTLRKLEKALGIS 67
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 8-62 9.46e-15

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 62.94  E-value: 9.46e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1339737984   8 IRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFL 62
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 5-63 1.15e-11

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 55.37  E-value: 1.15e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1339737984   5 GNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLL 63
Cdd:pfam12844   1 GERLRKAREERGLTQEELAERLGISRSQLSAIENGKSVPPAETLYKIAELLGVPANWLL 59
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
 3-66 2.51e-10

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 52.71  E-value: 2.51e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1339737984   3 TFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLLGRD 66
Cdd:COG3620    17 TLGEALRLMRKELGLSQLPVAELVGVSQSDILRIESGKRDPTVSTLEKIAEALGKELSAVLVVD 80
VapI COG3093
Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense ...
 5-77 1.68e-07

Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense mechanisms];


Pssm-ID: 442327 [Multi-domain]  Cd Length: 87  Bit Score: 45.19  E-value: 1.68e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1339737984   5 GNIIR-DLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLLG--RDFDVERNRNDSE 77
Cdd:COG3093    10 GEILReEFLEPLGLSQTELAKALGVSRQRISEILNGKRAITADTALRLARAFGTSAEFWLNlqAAYDLWLARQKAG 85
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 4-60 1.91e-07

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 44.44  E-value: 1.91e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1339737984   4 FGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQ-PDYNTLIRIADYFKVSTD 60
Cdd:pfam13560   2 LGARLRRLRERAGLSQEALARRLGVSRSTLSRLETGRRGrPSPAVVERLARALGVDGA 59
PRK09706 PRK09706
transcriptional repressor DicA; Reviewed
 2-68 5.08e-07

transcriptional repressor DicA; Reviewed


Pssm-ID: 182039 [Multi-domain]  Cd Length: 135  Bit Score: 44.84  E-value: 5.08e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1339737984   2 KTFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLLGRDFD 68
Cdd:PRK09706    4 LTLGQRIRYRRKQLKLSQRSLAKAVKVSHVSISQWERDETEPTGKNLFALAKALQCSPTWLLFGDED 70
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
8-53 8.30e-07

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 42.61  E-value: 8.30e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1339737984   8 IRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYN--TLIRIAD 53
Cdd:COG2944    11 IRALRERLGLSQAEFAALLGVSVSTVRRWEQGRRKPSGAalKLLRLLE 58
couple_hipB TIGR03070
transcriptional regulator, y4mF family; Members of this family belong to a clade of ...
 2-53 7.63e-06

transcriptional regulator, y4mF family; Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions]


Pssm-ID: 213767 [Multi-domain]  Cd Length: 58  Bit Score: 39.95  E-value: 7.63e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1339737984   2 KTFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIAD 53
Cdd:TIGR03070   1 KQIGILVRARRKALGLTQADLADLAGVGLRFIRDLENGKPTVRLDKVLRVLD 52
PHA01976 PHA01976
helix-turn-helix protein
 7-65 2.66e-05

helix-turn-helix protein


Pssm-ID: 177330 [Multi-domain]  Cd Length: 67  Bit Score: 39.17  E-value: 2.66e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1339737984   7 IIRdLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLLGR 65
Cdd:PHA01976    7 LIK-ARNARAWSAPELSRRAGVRHSLIYDFEADKRLPNLKTLLRLADALGVTLDWLCGR 64
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
 1-66 5.51e-05

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 40.49  E-value: 5.51e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1339737984   1 MKTFGNIIRDLRKQKGITQKELAQSLQ-----LSESTIGMYERNERQPDYNTLIRIADYFKVSTDFLLGRD 66
Cdd:PRK13355    1 KTTFAERLKQAMKARGLKQEDLVHAAEargvkLGKSHISQYVSGKTGPRRDVLPFLAAILGVSEDWLLGGE 71
YozG COG3655
DNA-binding transcriptional regulator, XRE family [Transcription];
8-58 1.17e-04

DNA-binding transcriptional regulator, XRE family [Transcription];


Pssm-ID: 442872 [Multi-domain]  Cd Length: 69  Bit Score: 37.43  E-value: 1.17e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1339737984   8 IRDLRKQKGITQKELAQSLQLSESTIGMYERNE-RQPDYNTLIRIADYFKVS 58
Cdd:COG3655     6 LDELLAERGMTKKELAEATGISRATLSRLKNGKaKAVRLDTLEKICKALDCQ 57
COG1395 COG1395
Predicted transcriptional regulator [Transcription];
5-57 1.57e-04

Predicted transcriptional regulator [Transcription];


Pssm-ID: 441005 [Multi-domain]  Cd Length: 313  Bit Score: 39.05  E-value: 1.57e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1339737984   5 GNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKV 57
Cdd:COG1395   129 GEKLRELREERGLSLGELASELGVSRRTISKYERGEMDASIEVALKLEEILGE 181
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 8-53 2.16e-04

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 37.61  E-value: 2.16e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1339737984   8 IRDLRKQKGITQKELAQSLQLSESTIGMYERNE-RQPDYNT-LIRIAD 53
Cdd:TIGR03830  70 IRRIRKKLGLSQREAAELLGGGVNAFSRYERGEvRPSKALDkLLRLLD 117
PRK04140 PRK04140
transcriptional regulator;
5-57 2.97e-04

transcriptional regulator;


Pssm-ID: 235224 [Multi-domain]  Cd Length: 317  Bit Score: 38.30  E-value: 2.97e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1339737984   5 GNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKV 57
Cdd:PRK04140  128 GDVLREAREELGLSLGELASELGVSRRTISKYENGGMNASIEVAIKLEEILDV 180
HTH_26 pfam13443
Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to ...
 8-68 4.30e-04

Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433211 [Multi-domain]  Cd Length: 63  Bit Score: 35.59  E-value: 4.30e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1339737984   8 IRDLRKQKGITQKELAQSLQLSESTIGMYERNE-RQPDYNTLIRIADYFKVSTDFLLGRDFD 68
Cdd:pfam13443   2 LRKLMADRGISKSDLARATGISRATLSRLRKGKpKRVSLDTLDKICDALGCQPGDLLEYVPD 63
PRK02362 PRK02362
ATP-dependent DNA helicase;
7-88 4.01e-03

ATP-dependent DNA helicase;


Pssm-ID: 235032 [Multi-domain]  Cd Length: 737  Bit Score: 35.32  E-value: 4.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1339737984   7 IIRDLRKQKGITQKELaqsLQLSESTIGMYERNERQPDYNTLIRIAdyFKVSTDFLLgrdfDVERNRNDSELDQWLNDIK 86
Cdd:PRK02362  509 IIDGLEAAKKPTDLGL---LHLVCSTPDMYELYLRSGDYEWLNEYL--YEHEDELLG----DVPSEFEDDEFEDFLSAVK 579


                  ..
gi 1339737984  87 LA 88
Cdd:PRK02362  580 TA 581
PRK09726 PRK09726
type II toxin-antitoxin system antitoxin HipB;
2-58 6.73e-03

type II toxin-antitoxin system antitoxin HipB;


Pssm-ID: 182049  Cd Length: 88  Bit Score: 33.03  E-value: 6.73e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1339737984   2 KTFGNIIRDLRKQKGITQKELAQSLQLSESTIGMYERNERQPDYNTLIRIADYFKVS 58
Cdd:PRK09726   11 TQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELS 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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