NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1353717984|ref|WP_105134261|]
View 

signal peptidase II [Streptococcus suis]

Protein Classification

signal peptidase II( domain architecture ID 10001765)

signal peptidase II specifically catalyzes the removal of signal peptides from membrane prolipoproteins; it belongs to the peptidase family A8

EC:  3.4.23.36
Gene Ontology:  GO:0004190|GO:0006508
MEROPS:  A8
PubMed:  31214988

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 8-150 5.46e-50

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 157.19  E-value: 5.46e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   8 FLMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKGNFW 87
Cdd:COG0597     5 LLALLVLLLDQLTKLWVVANLALGESIPVIGGFFNLTYVENTGAAFGLLAGAGWLLIILALVVLVGLLYYLRRLKKRSKL 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1353717984  88 TLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDF--ISFPVFNVADVCLTVGVGILFICIMKEESN 150
Cdd:COG0597    85 LALALGLILGGALGNLIDRLFYGYVVDFIDFHIggWHWPIFNVADIAITIGVILLLLDSLFGKKK 149
 
Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 8-150 5.46e-50

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 157.19  E-value: 5.46e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   8 FLMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKGNFW 87
Cdd:COG0597     5 LLALLVLLLDQLTKLWVVANLALGESIPVIGGFFNLTYVENTGAAFGLLAGAGWLLIILALVVLVGLLYYLRRLKKRSKL 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1353717984  88 TLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDF--ISFPVFNVADVCLTVGVGILFICIMKEESN 150
Cdd:COG0597    85 LALALGLILGGALGNLIDRLFYGYVVDFIDFHIggWHWPIFNVADIAITIGVILLLLDSLFGKKK 149
Peptidase_A8 pfam01252
Signal peptidase (SPase) II;
9-146 1.03e-48

Signal peptidase (SPase) II;


Pssm-ID: 460136 [Multi-domain]  Cd Length: 140  Bit Score: 153.39  E-value: 1.03e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   9 LMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKGNFWT 88
Cdd:pfam01252   1 IALLLLLLDQLTKLLIVKNLKLGEPIEVIPGFFNLTYVENTGAAFGLLAGQRWLLIILTLVAIILLIYLLLKLKKKSRLL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  89 LFSLSLMIAGALGNFIDRLRLGYVVDM--FHLDFISFPVFNVADVCLTVGVGILFICIMK 146
Cdd:pfam01252  81 RIALALILGGALGNLIDRLFYGYVVDFidFHIGFINFPVFNVADIAITVGVILLIIDLLF 140
PRK14791 PRK14791
lipoprotein signal peptidase; Provisional
 8-148 4.09e-37

lipoprotein signal peptidase; Provisional


Pssm-ID: 237817 [Multi-domain]  Cd Length: 146  Bit Score: 124.29  E-value: 4.09e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   8 FLMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKGNFW 87
Cdd:PRK14791    4 IIIILGIFLDQLTKIWALKNLASGGDIPVIKNFFSLTYVENRGAAFGILQNKTLFLILITIIVILGLIYYIIKYKPTSKL 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1353717984  88 TLFSLSLMIAGALGNFIDRLRLGYVVD--MFHLDFISFPVFNVADVCLTVGVGILFICIMKEE 148
Cdd:PRK14791   84 YKISLSLIISGAIGNLIDRIRYGYVVDfiDFHFKDYYFPVFNVADILVVVGTILLAIYILKEE 146
lspA TIGR00077
lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, ...
 10-143 1.84e-26

lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 272893 [Multi-domain]  Cd Length: 166  Bit Score: 97.81  E-value: 1.84e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  10 MVVLIGLDQLVKAWTVANVEL-DTVTEFIPGLMSLAYLRNYGAAWSILQN---QQWFFTIMTIVAVTGLVWYYIKQIKGN 85
Cdd:TIGR00077  16 AILFIGFDQLSKYLVLQNFDLgETYFVAFSGVFNITYVRNTGAAFSLLADqggQVYFLKGLAIAISLGLFVFLLRYKELF 95

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  86 FWTLFSLSLMIAGALGNFIDRLRLGYVVDM--FHLDFISFPVFNVADVCLTVGVGILFIC 143
Cdd:TIGR00077  96 KITNIAFGLIFGGALGNFIDRLVRGGVVDFfdFYFGNYHFPIFNFADSSICIGVILLLLY 155
 
Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 8-150 5.46e-50

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 157.19  E-value: 5.46e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   8 FLMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKGNFW 87
Cdd:COG0597     5 LLALLVLLLDQLTKLWVVANLALGESIPVIGGFFNLTYVENTGAAFGLLAGAGWLLIILALVVLVGLLYYLRRLKKRSKL 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1353717984  88 TLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDF--ISFPVFNVADVCLTVGVGILFICIMKEESN 150
Cdd:COG0597    85 LALALGLILGGALGNLIDRLFYGYVVDFIDFHIggWHWPIFNVADIAITIGVILLLLDSLFGKKK 149
Peptidase_A8 pfam01252
Signal peptidase (SPase) II;
9-146 1.03e-48

Signal peptidase (SPase) II;


Pssm-ID: 460136 [Multi-domain]  Cd Length: 140  Bit Score: 153.39  E-value: 1.03e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   9 LMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKGNFWT 88
Cdd:pfam01252   1 IALLLLLLDQLTKLLIVKNLKLGEPIEVIPGFFNLTYVENTGAAFGLLAGQRWLLIILTLVAIILLIYLLLKLKKKSRLL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  89 LFSLSLMIAGALGNFIDRLRLGYVVDM--FHLDFISFPVFNVADVCLTVGVGILFICIMK 146
Cdd:pfam01252  81 RIALALILGGALGNLIDRLFYGYVVDFidFHIGFINFPVFNVADIAITVGVILLIIDLLF 140
PRK14791 PRK14791
lipoprotein signal peptidase; Provisional
 8-148 4.09e-37

lipoprotein signal peptidase; Provisional


Pssm-ID: 237817 [Multi-domain]  Cd Length: 146  Bit Score: 124.29  E-value: 4.09e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   8 FLMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKGNFW 87
Cdd:PRK14791    4 IIIILGIFLDQLTKIWALKNLASGGDIPVIKNFFSLTYVENRGAAFGILQNKTLFLILITIIVILGLIYYIIKYKPTSKL 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1353717984  88 TLFSLSLMIAGALGNFIDRLRLGYVVD--MFHLDFISFPVFNVADVCLTVGVGILFICIMKEE 148
Cdd:PRK14791   84 YKISLSLIISGAIGNLIDRIRYGYVVDfiDFHFKDYYFPVFNVADILVVVGTILLAIYILKEE 146
PRK14767 PRK14767
lipoprotein signal peptidase; Provisional
 4-148 3.15e-27

lipoprotein signal peptidase; Provisional


Pssm-ID: 237811  Cd Length: 174  Bit Score: 99.78  E-value: 3.15e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   4 IGFPFLMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIK--Q 81
Cdd:PRK14767   11 IKYGILFVILVILDQITKYLAVSHLADKPSFVIIPGVFELIYLENSGAAFGMLSGKAVFFLVITVAVVIIMAFVFFKlpA 90

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  82 IKGNFWTLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDFISFPVFNVADVCLTVGVG---ILFICIMKEE 148
Cdd:PRK14767   91 TKKYNPLHIILVFIVAGAAGNLIDRILNGYVVDFIYFKLINFPIFNVADIYVTVSTFlfiILFLFYYKED 160
lspA TIGR00077
lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, ...
 10-143 1.84e-26

lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 272893 [Multi-domain]  Cd Length: 166  Bit Score: 97.81  E-value: 1.84e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  10 MVVLIGLDQLVKAWTVANVEL-DTVTEFIPGLMSLAYLRNYGAAWSILQN---QQWFFTIMTIVAVTGLVWYYIKQIKGN 85
Cdd:TIGR00077  16 AILFIGFDQLSKYLVLQNFDLgETYFVAFSGVFNITYVRNTGAAFSLLADqggQVYFLKGLAIAISLGLFVFLLRYKELF 95

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  86 FWTLFSLSLMIAGALGNFIDRLRLGYVVDM--FHLDFISFPVFNVADVCLTVGVGILFIC 143
Cdd:TIGR00077  96 KITNIAFGLIFGGALGNFIDRLVRGGVVDFfdFYFGNYHFPIFNFADSSICIGVILLLLY 155
PRK14790 PRK14790
lipoprotein signal peptidase; Provisional
 11-140 6.09e-25

lipoprotein signal peptidase; Provisional


Pssm-ID: 173251  Cd Length: 169  Bit Score: 93.77  E-value: 6.09e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  11 VVLIGLDQLVKAWTVANVELDTVTEFIPGL---MSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKG-NF 86
Cdd:PRK14790   17 ATILALDQASKRWILATLGPVPMTKFIPLIgedIRLAYSHNTGIAFSLFDGKSDILTVVALVISLGAIYLYRTQLPNrRL 96

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1353717984  87 WTLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDFisFPVFNVADVCLTVGVGIL 140
Cdd:PRK14790   97 LIQVAMGLILGGALGNVIDRIRLGYVVDFIQVGW--FPIFNLADSAITVGAALL 148
PRK14777 PRK14777
lipoprotein signal peptidase; Provisional
 1-148 7.81e-24

lipoprotein signal peptidase; Provisional


Pssm-ID: 237814 [Multi-domain]  Cd Length: 184  Bit Score: 91.45  E-value: 7.81e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   1 MRKIGFP-----FLMVVLIGLDQLVKAWTVANVELDT-VTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGL 74
Cdd:PRK14777   19 ERQRGVPawaplVLATLLIVLDQALKAWALANLQLGApAIPVLPGVLDWVLTFNTGAAWSLFSGSALPLALMRLLVGLGL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  75 VWYYIKQIKGNFWTLfSLSLMIAGALGNFIDRLRLGYVVDMFHLDFIS----------FPVFNVADVCLTVGVGILFICI 144
Cdd:PRK14777   99 LVYLLRRPQPRFLTV-VLSLIAAGAIGNAIDGLRFGRVTDMLHSPALSavtralgqgdFPIFNLADMCVVGGTLLLLFAS 177


                  ....
gi 1353717984 145 MKEE 148
Cdd:PRK14777  178 FQQD 181
PRK14786 PRK14786
lipoprotein signal peptidase; Provisional
 9-153 4.74e-20

lipoprotein signal peptidase; Provisional


Pssm-ID: 173247  Cd Length: 154  Bit Score: 80.79  E-value: 4.74e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   9 LMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKG-NFW 87
Cdd:PRK14786    6 IITILTGIDQWTKYLIETQLKPIGAIPIVKDIFHLTYARNTGAAFSILRDKQAFLILVTTIVVGALIYYLIKILKTgEVA 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1353717984  88 TLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDFISFPVFNVADVCLTVGVGILFICIMKEESNGSK 153
Cdd:PRK14786   86 FKLSLAIIIGGALGNLIDRVRLNYVTDFLDFTLINYPIFNLADVFVVSGVVMLSYMLLFKGDMPKI 151
PRK14768 PRK14768
lipoprotein signal peptidase; Provisional
 6-149 2.62e-19

lipoprotein signal peptidase; Provisional


Pssm-ID: 173229  Cd Length: 148  Bit Score: 78.79  E-value: 2.62e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   6 FPFLMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAvTGLVWYYIKQIKGN 85
Cdd:PRK14768    3 YILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVENRGAAFGLLQNNQWIFIIVALLA-TVFGLYYLNTRKVH 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1353717984  86 FWTLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDFISFPVFNVADVCLTVGVGILFICIMKEES 149
Cdd:PRK14768   82 IFGRLGIILIISGALGNLIDRVRLGFVVDYFDFRVIWEYVFNVADVFVVVGTVFLCIYVLFFES 145
PRK14785 PRK14785
lipoprotein signal peptidase; Provisional
 2-142 8.21e-19

lipoprotein signal peptidase; Provisional


Pssm-ID: 184820  Cd Length: 171  Bit Score: 77.94  E-value: 8.21e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   2 RKIGFPFLMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQN----QQWFFTIMTIVAVTGLVWY 77
Cdd:PRK14785   13 RALNWYLLSLVVLILDQWTKWLAETKLTFLEPVPVIEPFLNWTLAYNYGAAFSFLADaggwQKWFFAGLALIMSLFLIVY 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1353717984  78 YIKQIKGNFWTLFSLSLMIAGALGNFIDRLRLGYVVDMFHL---DFISFPVFNVADVCLTVGVGILFI 142
Cdd:PRK14785   93 LKKAPRQAKLLSLGLALVLGGAIGNLIDRLLHGHVIDFIHVhyaDVWHYPIFNIADIGICVGVALIVI 160
PRK14772 PRK14772
lipoprotein signal peptidase; Provisional
 6-145 1.36e-18

lipoprotein signal peptidase; Provisional


Pssm-ID: 237812 [Multi-domain]  Cd Length: 190  Bit Score: 77.99  E-value: 1.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   6 FPFLMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFT-IMTIVAVTGLVwyyikQIK- 83
Cdd:PRK14772   28 FAGFAVFAYVFDQLTKLWVTSTMVEGERIPVLPPLLHWYYIRNSGAAFSIGENVTWVFSiIMAAVAVAILV-----QLRk 102

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1353717984  84 -GNFWTLFSLSLMIAGALGNFIDRL------RLGYVVDMFHLDfiSFPVFNVADVCLTVGVGIlfICIM 145
Cdd:PRK14772  103 lGSAWWALALGLLLGGALGNLTDRLfrepsfGMGHVVDFIQLP--NFAIFNIADSAVVSGVVI--ICLL 167
PRK14773 PRK14773
lipoprotein signal peptidase; Provisional
 45-142 1.51e-18

lipoprotein signal peptidase; Provisional


Pssm-ID: 173234  Cd Length: 192  Bit Score: 77.96  E-value: 1.51e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  45 YLRNYGAAWSILQN-----QQWFFTIMTIVAVTGLVWYYIKQIKGNFWTLFSLSLMIAGALGNFIDRLRLGYVVDMFHLD 119
Cdd:PRK14773   74 YVENPGAAWGLFRGhseefRNAFFTLVSLAAVAFILHYYRKLRQEQRYLQVALALVLGGAVGNFVDRLARGYVIDFIEWY 153

                          90       100
                  ....*....|....*....|....*...
gi 1353717984 120 F-----ISFPVFNVADVCLTVGVGILFI 142
Cdd:PRK14773  154 WwnrpdIRWPTFNVADSLIVVGVAMLVL 181
PRK14784 PRK14784
lipoprotein signal peptidase; Provisional
 5-154 1.55e-16

lipoprotein signal peptidase; Provisional


Pssm-ID: 184819 [Multi-domain]  Cd Length: 160  Bit Score: 71.81  E-value: 1.55e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   5 GFPFLMVVLIGL--DQLVKAWTVANVeldTVTEFIP--GLMSLAYLRNYGAAWSILQNQ-QWFFTIMTIVAVTGLVWYYI 79
Cdd:PRK14784    4 GLVFFVSTACGIlaDQLSKFIITANL---TTGTSIPesGFFQIVHVHNTGAAFSIFRGHiEWLIAASVLGVILAMTAFFI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  80 KQIKGNFWT---LFSLSLMIAGALGNFIDRLRLGYVVdmfhlDFIS---FPVFNVADVCLTVGVGILFICIMKEESNGSK 153
Cdd:PRK14784   81 RKKLPFLDTrpgLIALGVILAGTVGNLIDRVRLGYVT-----DFIRvgdFPTFNIADSCLTVGVIGLLLLYLVSSHVSGD 155


                  .
gi 1353717984 154 S 154
Cdd:PRK14784  156 T 156
PRK14771 PRK14771
lipoprotein signal peptidase; Provisional
 6-152 5.30e-16

lipoprotein signal peptidase; Provisional


Pssm-ID: 184816  Cd Length: 165  Bit Score: 70.61  E-value: 5.30e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   6 FPFLMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWyYIKQIKGN 85
Cdd:PRK14771   15 FACIAIAALIVDQLTKAWAQAALSDGQTIRVIPGLLSLTLVRNPGASLGMGSGATWVISLLAIVACVALVV-AAVRTISM 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1353717984  86 FWTLFsLSLMIAGALGNFIDRLRL------GYVVDMFHLdfiSFPVFNVADVCLTV-GVGILFICIMKEESNGS 152
Cdd:PRK14771   94 KWTVA-LALAFAGALGNLIDRVMYaqgflnGKVVDFLNY---GWSVGNVADIFLMIaGIALVILILMGEPFSHK 163
PRK14787 PRK14787
lipoprotein signal peptidase; Provisional
 6-142 1.32e-15

lipoprotein signal peptidase; Provisional


Pssm-ID: 173248  Cd Length: 159  Bit Score: 69.26  E-value: 1.32e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   6 FPFLMVVLIGLDQLVKAWTVANV-ELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKG 84
Cdd:PRK14787    4 FFLLALAVIVLDQFTKKLAITFLrDGPQSITIIPDWFKLTYAENRGIAFGLEFAPPEVLLLLTGAISAGVLWYVLRSKNR 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1353717984  85 NFWTLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDFIS----------FPVFNVADVCLTVGVGILFI 142
Cdd:PRK14787   84 TPLFLLAFGLILGGGIGNLIDRITSGRVVDFIYFDLYQgyifgiwvslWPIFNIADSAITIGACMLLL 151
PRK14788 PRK14788
lipoprotein signal peptidase; Provisional
 1-143 1.18e-14

lipoprotein signal peptidase; Provisional


Pssm-ID: 237816  Cd Length: 200  Bit Score: 67.68  E-value: 1.18e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   1 MRKIGFPFLMVVLIglDQLVKAWTVANVELDTVTEFIPGLmSLAYLRNYGAAWSI---LQNQQWFFTIMTIVAVTGLVWY 77
Cdd:PRK14788    1 LKKAFLIILLVLLI--DQISKIYVKTHFVLGQSVLVFDWF-KIHFVENPGMAFGMelgGEYGKLFLTLFRIVAVGGIGYY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  78 YIKQIKGNF--WTLFSLSLMIAGALGNFIDR---------------------------LRLGYVVDMFHLDFISF----- 123
Cdd:PRK14788   78 LWKLVKKNSskGLIICISLILAGAIGNIIDSvfygvifdngsygqiatffpegggystWFHGKVVDMFYFPIIDGylpew 157

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1353717984 124 -------------PVFNVADVCLTVGVGILFIC 143
Cdd:PRK14788  158 vpfwggehfvffkPVFNIADSAISIGVILLLLF 190
PRK14781 PRK14781
lipoprotein signal peptidase; Provisional
 1-140 7.50e-14

lipoprotein signal peptidase; Provisional


Pssm-ID: 237815  Cd Length: 153  Bit Score: 64.83  E-value: 7.50e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   1 MRKIGFPFLMVVLIGLDQLVKAWTVANVELDTVTEFipGLMSLAYLRNYGAAWSILQN-QQWFFTIMTIVAVTGLVWYYI 79
Cdd:PRK14781    1 RRRGGLLLWAALLAGADLLVKAQAEAGLSRGEVIDL--GLINIRLLYNTGVAFSLGAGlPTWFVIAGTGLIIAALLWYLT 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1353717984  80 KQI-KGNFWTLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDFisFPVFNVADVCLTVGVGIL 140
Cdd:PRK14781   79 SSApKMSRLSRAGAALLLGGAVGNFIDRLDGRGVVDYLHSGW--FPTFNLADVFVTTGVALL 138
PRK14789 PRK14789
lipoprotein signal peptidase; Provisional
 8-140 6.03e-13

lipoprotein signal peptidase; Provisional


Pssm-ID: 173250  Cd Length: 191  Bit Score: 63.13  E-value: 6.03e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   8 FLMVVLIGLDQLVKAW-TVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMT--IVAVTGLVWYYIKQIKG 84
Cdd:PRK14789   10 LVAIPVFVIDQLSKVWlSDVLLRYNRPIPLLFDWVQLAYHENTGVAFGLFPDQGGVLSVGAglVLLLLALTYQYILPADS 89

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1353717984  85 NfWTLFSLSLMIAGALGNFIDRLRLGYVVDMfhLDFISFPVFNVADVCLTVGVGIL 140
Cdd:PRK14789   90 R-WITVAVGMIFGGGLSNLVDRIRQGYVVDF--IQFGWWPVFNLADSAITIGVAAL 142
PRK14770 PRK14770
lipoprotein signal peptidase; Provisional
 2-142 2.56e-12

lipoprotein signal peptidase; Provisional


Pssm-ID: 173231  Cd Length: 167  Bit Score: 60.99  E-value: 2.56e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   2 RKIGFPFLMVVLIgLDQLVKAWTVANVELDT--VTEFIPGLmSLAYLRNYGAAWSILQNQ----QWFFTIMTIVAVTGLV 75
Cdd:PRK14770   10 RTLGAALLVAVLL-LDQASKYWILYGLDLPDrgSVPVLPFL-NFTMVWNHAVTFGMLGGLggigRVVFSAVSLAAVLLLG 87

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1353717984  76 WYYIKQIKgnFWTLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDF--ISFPVFNVADVCLTVGVGILFI 142
Cdd:PRK14770   88 VWLTRTPR--PLVAAALGAIMGGAIGNVIDRMRYGAVVDFLHAHAfgWSWYVFNLADAAIDCGVAVLLI 154
PRK14778 PRK14778
lipoprotein signal peptidase; Provisional
 8-154 2.96e-12

lipoprotein signal peptidase; Provisional


Pssm-ID: 173239  Cd Length: 186  Bit Score: 60.98  E-value: 2.96e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   8 FLMVVLIGLDQLVKAWTVanvELDTVTEFIPGLMSLAYLRNYGAAWSILQN--QQWFFTIMTIVAVTGLVWYYIKQikgN 85
Cdd:PRK14778    3 FVIVLTIVLDQLTKRIAS---EIHGTFFIVPGFLRFVKATNRGVALGLFSNlsEQVLWTVLFVVVFLSLLPYIFRF---S 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1353717984  86 FWTLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDFISfPVFNVADVCLTVGVGILFICIMKEESNGSKS 154
Cdd:PRK14778   77 RLERMAMGFILGGALGNLLDRIRFGYVLDFLNLTFLP-TIFNLADVFIIVGGALMILGVFRGGDNESLE 144
PRK14775 PRK14775
lipoprotein signal peptidase; Provisional
 10-144 3.00e-10

lipoprotein signal peptidase; Provisional


Pssm-ID: 237813  Cd Length: 170  Bit Score: 55.67  E-value: 3.00e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  10 MVVLIGLDQLVKAWTVANVELDTVTEfIPGLMSLAYLRNYGAAW---SILQNQQWFFTIMTIVAVTGLVWYYIkQIKGNF 86
Cdd:PRK14775   11 IVLVFALDQVSKAYAIDWYSQSGATE-VFKFCSLVEVWNRGISFgmfGALESSNLIFTYVSLGVILMLFVLFV-QSKCNK 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  87 WTlFSLSLMIAGALGNFIDRLRLGYVVDM--FHLDFISFPVFNVADVCLTVGVgILFICI 144
Cdd:PRK14775   89 ST-ICMGVVIGGALGNLADRLRFGAVYDFisLHAGEFHWPAFNFADVCVTCGV-ICFLCL 146
PRK14776 PRK14776
lipoprotein signal peptidase; Provisional
 7-142 4.55e-08

lipoprotein signal peptidase; Provisional


Pssm-ID: 173237  Cd Length: 170  Bit Score: 49.55  E-value: 4.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   7 PFLMVVLIGL----DQLVKaWTV----ANVELDTVTEFipglMSLAYLRNYGAAWSILQN----QQWFFTIMTIVAVTGL 74
Cdd:PRK14776   10 PYALLSISGLlaasDQAVK-WLVqqsmAYGEYVSVTPF----FNWVHLWNTGAAFSLFANgggwQRYFFIGIAVVVSIFL 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1353717984  75 VWYYIK-QIKGNfwtLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDFIS--FPVFNVADVCLTVGVgILFI 142
Cdd:PRK14776   85 IKLILEnRHKGE---AIAYSLILGGAMGNLIDRVFRGYVVDSFDFYWRDwhWPAFNLADIAIVLGA-LLFV 151
PRK14766 PRK14766
lipoprotein signal peptidase; Provisional
 9-147 1.82e-07

lipoprotein signal peptidase; Provisional


Pssm-ID: 173227  Cd Length: 201  Bit Score: 48.33  E-value: 1.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   9 LMVVLIGLDQLVKAWTVANVELDTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIkqIKGNFWT 88
Cdd:PRK14766   30 IFISLISFDWIIKAVVVSHMKLGETKTFISGFLNFQYVINLGMAYGRLADKLYLVIIFATIFSLFLTIVFI--FLNNKKW 107

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1353717984  89 LFSLSLMIAGALGNFIDRL--------RLGYVVDMFHLDFISFP----VFNVADVCLTVGVGILFICIMKE 147
Cdd:PRK14766  108 LIVLSILLAGSWGNLLARLwapgneqnIYGGVVDFLTWDFSLLNsrdyVFNLADLYVNIAIGLTILFTIIE 178
PRK14769 PRK14769
lipoprotein signal peptidase; Provisional
 11-140 2.95e-07

lipoprotein signal peptidase; Provisional


Pssm-ID: 173230  Cd Length: 156  Bit Score: 47.22  E-value: 2.95e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  11 VVLIGLDQLVKAWTVANVELDTVTEfipGLMSLAYLRNYGAAWSILQNqqwfFTIMTIVAVTG-----LVWYYIKQIKGN 85
Cdd:PRK14769   13 VIIAGIDLGAKAWSERQLAGSSVDL---GLLHLRLAFNSGVAFSMGDT----LPVGVIVAVTAvivvaLAVYAWRRAPTA 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1353717984  86 FWT-LFSLSLMIAGALGNFIDRLRLGYVVDMFHLDFisFPVFNVADVCLTVGVGIL 140
Cdd:PRK14769   86 GWVeRIAGGAVIGGALANVVDRARDGLVTDYLHTGW--WPTFNLADTFLVTGFAVI 139
PRK14779 PRK14779
lipoprotein signal peptidase; Provisional
 30-140 4.70e-07

lipoprotein signal peptidase; Provisional


Pssm-ID: 184818  Cd Length: 159  Bit Score: 46.62  E-value: 4.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  30 LDTVTEFIPgLMSLAYLRNYGAAWSILQNQQWF-----FTIMTIVAVTGLVWYYIKqiKGNFWTLFSLSLMIAGALGNFI 104
Cdd:PRK14779   31 FDKDISVIP-FLDLVLVYNKGVAFGLLSEAPDFirlpiLLLTPIIALIITFLYALK--SNDKLSNLSMGLIGGGALGNLY 107

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1353717984 105 DRLRLGYVVDM--FHLDFISFPVFNVADVCLTVGVGIL 140
Cdd:PRK14779  108 DRFFLGQVRDFidIYIGDFHWPAFNIADASISIGIALF 145
PRK14774 PRK14774
lipoprotein signal peptidase; Provisional
 1-136 1.21e-05

lipoprotein signal peptidase; Provisional


Pssm-ID: 173235  Cd Length: 185  Bit Score: 43.08  E-value: 1.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984   1 MRKIGFPFLMVVLIglDQLVKAWTVANVEL------DTVTEFIPGLMSLAYLRNYGAAWSILQNQQWFFTIMTIvAVTGL 74
Cdd:PRK14774    1 MRLAALTAFGVFVL--DQLTKWLVVWGLDLanrgaiDLVAPWLTFRMAWNRGINFGIGSSDQEIVRWGLVIVSL-AISAW 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1353717984  75 VWYYIKQIKGNFWTLFSLSLMIAGALGNFIDRLRLGYVVDMFHLDF--ISFP-VFNVADVCLTVG 136
Cdd:PRK14774   78 VWRWVWRSTPTRLARISGGLLIGGALGNVVDRVLYGAVADFLNMSCcgIENPyAFNVADIAIFAG 142
PRK14783 PRK14783
lipoprotein signal peptidase; Provisional
 41-148 5.91e-04

lipoprotein signal peptidase; Provisional


Pssm-ID: 173244  Cd Length: 182  Bit Score: 38.31  E-value: 5.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1353717984  41 MSLAYlrNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIK-GNFWtlfSLSLMIAGALGNFIDRL---------RLG 110
Cdd:PRK14783   53 MTLTF--NTGFVFGAFQDNAIPSLIATGFAIVFLIGYRWKNSDlGNPW---GWNLVMAGAFGNFLDKFfvkipgtgfRFG 127

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1353717984 111 Y---------VVDMFHLDFISF------PVFNVADVCLTVGVGILFICIMKEE 148
Cdd:PRK14783  128 FqpnkgeyigVVDFLDFDWPDFllfsrwPAFNVADSCVTIGLTILIFTMKLEE 180
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH