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Conserved domains on  [gi|1357953556|ref|WP_105316249|]
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hypothetical protein [Lactiplantibacillus plantarum]

Protein Classification

CHY zinc finger protein( domain architecture ID 142325)

CHY zinc finger protein may bind zinc ions though conserved cysteine and histidine residues; similar to Kluyveromyces lactis helper of Tim protein 13, which is required for the assembly or recycling of the small Tim proteins in the mitochondrial intermembrane, thereby participating in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane

Gene Ontology:  GO:0008270
PubMed:  11179890|12665246

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CHY super family cl19861
CHY zinc finger; This family of domains are likely to bind to zinc ions. They contain many ...
 6-102 3.46e-29

CHY zinc finger; This family of domains are likely to bind to zinc ions. They contain many conserved cysteine and histidine residues. We have named this domain after the N-terminal motif CXHY. This domain can be found in isolation in some proteins, but is also often associated with pfam00097. One of the proteins in this family is a mitochondrial intermembrane space protein called Hot13. This protein is involved in the assembly of small TIM complexes.


The actual alignment was detected with superfamily member COG4357:

Pssm-ID: 473236  Cd Length: 107  Bit Score: 101.15  E-value: 3.46e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357953556   6 PVIYGIGLDAAGRCQHYHLETDIAALWCRRCQRYYACYRCHDTLCQHTFVASAPTDL---AVMCGACRYRMPVDRYHEGQ 82
Cdd:COG4357     5 IEVRGVVVDDETRCAHYHSELDVIAIKFACCGKYYPCYRCHEELADHEAEPWPRERFdekAVLCGVCGTELTINEYLEAD 84

                          90       100
                  ....*....|....*....|.
gi 1357953556  83 -CPHCHRPFNPRYRLHDKVYF 102
Cdd:COG4357    85 sCPACGAAFNPGCALHYHLYF 105
 
Name Accession Description Interval E-value
COG4357 COG4357
Uncharacterized conserved protein, contains Zn-finger domain of CHY type [Function unknown];
6-102 3.46e-29

Uncharacterized conserved protein, contains Zn-finger domain of CHY type [Function unknown];


Pssm-ID: 443492  Cd Length: 107  Bit Score: 101.15  E-value: 3.46e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357953556   6 PVIYGIGLDAAGRCQHYHLETDIAALWCRRCQRYYACYRCHDTLCQHTFVASAPTDL---AVMCGACRYRMPVDRYHEGQ 82
Cdd:COG4357     5 IEVRGVVVDDETRCAHYHSELDVIAIKFACCGKYYPCYRCHEELADHEAEPWPRERFdekAVLCGVCGTELTINEYLEAD 84

                          90       100
                  ....*....|....*....|.
gi 1357953556  83 -CPHCHRPFNPRYRLHDKVYF 102
Cdd:COG4357    85 sCPACGAAFNPGCALHYHLYF 105
zf-CHY pfam05495
CHY zinc finger; This family of domains are likely to bind to zinc ions. They contain many ...
 19-87 7.90e-06

CHY zinc finger; This family of domains are likely to bind to zinc ions. They contain many conserved cysteine and histidine residues. We have named this domain after the N-terminal motif CXHY. This domain can be found in isolation in some proteins, but is also often associated with pfam00097. One of the proteins in this family is a mitochondrial intermembrane space protein called Hot13. This protein is involved in the assembly of small TIM complexes.


Pssm-ID: 461665  Cd Length: 75  Bit Score: 40.80  E-value: 7.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357953556  19 CQHYHLEtdiAALWCRRCQRYYACYRCHDTLCQ-HTFVASAPTDL-----------AVMCGACRYRMpvDRYHegqCPHC 86
Cdd:pfam05495   1 CKHYHRN---CKLRCPCCGKWYPCRLCHDEVEDeHPLDRYAVTEMlcmlcdteqpvAVLCGNCGVTF--AEYF---CPIC 72


                  .
gi 1357953556  87 H 87
Cdd:pfam05495  73 K 73
 
Name Accession Description Interval E-value
COG4357 COG4357
Uncharacterized conserved protein, contains Zn-finger domain of CHY type [Function unknown];
6-102 3.46e-29

Uncharacterized conserved protein, contains Zn-finger domain of CHY type [Function unknown];


Pssm-ID: 443492  Cd Length: 107  Bit Score: 101.15  E-value: 3.46e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357953556   6 PVIYGIGLDAAGRCQHYHLETDIAALWCRRCQRYYACYRCHDTLCQHTFVASAPTDL---AVMCGACRYRMPVDRYHEGQ 82
Cdd:COG4357     5 IEVRGVVVDDETRCAHYHSELDVIAIKFACCGKYYPCYRCHEELADHEAEPWPRERFdekAVLCGVCGTELTINEYLEAD 84

                          90       100
                  ....*....|....*....|.
gi 1357953556  83 -CPHCHRPFNPRYRLHDKVYF 102
Cdd:COG4357    85 sCPACGAAFNPGCALHYHLYF 105
zf-CHY pfam05495
CHY zinc finger; This family of domains are likely to bind to zinc ions. They contain many ...
 19-87 7.90e-06

CHY zinc finger; This family of domains are likely to bind to zinc ions. They contain many conserved cysteine and histidine residues. We have named this domain after the N-terminal motif CXHY. This domain can be found in isolation in some proteins, but is also often associated with pfam00097. One of the proteins in this family is a mitochondrial intermembrane space protein called Hot13. This protein is involved in the assembly of small TIM complexes.


Pssm-ID: 461665  Cd Length: 75  Bit Score: 40.80  E-value: 7.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1357953556  19 CQHYHLEtdiAALWCRRCQRYYACYRCHDTLCQ-HTFVASAPTDL-----------AVMCGACRYRMpvDRYHegqCPHC 86
Cdd:pfam05495   1 CKHYHRN---CKLRCPCCGKWYPCRLCHDEVEDeHPLDRYAVTEMlcmlcdteqpvAVLCGNCGVTF--AEYF---CPIC 72


                  .
gi 1357953556  87 H 87
Cdd:pfam05495  73 K 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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