|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
5-1298 |
0e+00 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 2927.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 5 QNITLSALMARLDSLMLRDKSRFARRLHGAKKIKNTESQQALFEQLSQEMSEAAGKVLLREAARPAITYPENLPVSQKKQ 84
Cdd:PRK11131 1 MKLTLTALQQQLDELMLRDRQRLSRRLHGAKKIKNPDAQQAIFQEIAKEIAQAAQRVLLREAARPEITYPENLPVSQKKQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 85 DILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGYKVRFSDHV 164
Cdd:PRK11131 81 DILEAIRDHQVVIVAGETGSGKTTQLPKICLELGRGVKGLIGHTQPRRLAARTVANRIAEELETELGGCVGYKVRFNDQV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 165 SDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDPERFSRHFNNA 244
Cdd:PRK11131 161 SDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFILGYLKELLPRRPDLKVIITSATIDPERFSRHFNNA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 245 PIIEVSGRTYPVEVRYRPIVEEADDTERDQLQAIFDAVEELGREGPGDILIFMSGEREIRDTADGLMKLNLPHTEVLPLY 324
Cdd:PRK11131 241 PIIEVSGRTYPVEVRYRPIVEEADDTERDQLQAIFDAVDELGREGPGDILIFMSGEREIRDTADALNKLNLRHTEILPLY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 325 ARLSNSEQNRVFQPHAGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPVSQASANQRKGRCGRVS 404
Cdd:PRK11131 321 ARLSNSEQNRVFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVS 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 405 EGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDAQASVY 484
Cdd:PRK11131 401 EGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDEQASAY 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 485 KLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRERPLDKQQASDEKHRRFHDKESDFLAFVNLWNY 564
Cdd:PRK11131 481 KLTPLGRQLAQLPVDPRLARMVLEAQKHGCVREVMIITSALSIQDPRERPMDKQQASDEKHRRFADKESDFLAFVNLWNY 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 565 LGEQQKALSSNQFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAGYREVHTALLTGLLSHIGMKDADKQEY 644
Cdd:PRK11131 561 LQEQQKALSSNQFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHTALLTGLLSHIGMKDAEKQEY 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 645 TGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWIEPVAQHLIKRSYSEPHWERAQGAVMASEKVTL 724
Cdd:PRK11131 641 TGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIEPEWIEPLAQHLIKRSYSEPHWEKAQGAVMATEKVTL 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 725 YGLPIVAARSVNYSQIDPVLSRELFIRHALVEGDWQTRHAFFRENQKLRAEVEELEHKSRRRDILVDDDTLFEFYDQRIS 804
Cdd:PRK11131 721 YGLPIVAARKVNYGQIDPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYDQRIG 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 805 VDAISARHFDSWWKKASRETPDLLNFEKSMLIKEGAEKVSKLDYPNFWHQGNLKLRLTYQFEPGGDADGVTVHIPLPLLN 884
Cdd:PRK11131 801 HDVVSARHFDSWWKKASRETPELLNFEKSMLIKEGAEKVSKLDYPNFWHQGNLKLRLSYQFEPGADADGVTVHIPLPLLN 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 885 QVEDAGFEWQVPGMRRELIIALIKSLPKPVRRNFVPAPNYAEAFLGRVTPLELPLLDALERELRRMTGVTIDREAWQAEQ 964
Cdd:PRK11131 881 QVEESGFDWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVTPLELPLLDSLERELRRMTGVTVDREDWQWDQ 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 965 VPDHLKMTFRVVDEKGRKLREGKDLHALKEGLKEKVQETLSAVADDGIEQSGLHIWSFGTLPERYEQKRGGYQVKAFPAL 1044
Cdd:PRK11131 961 VPDHLKITFRVVDDKNKKLAEGKDLQELKDALKGKVQETLSAVADDGIEQSGLHIWSFGELPESYEQKRGGYKVKAYPAL 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 1045 VDEKESVGIRLFDNPQEQQHAMWRGQRRLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLDLIDDCISCGVDKLIAEN 1124
Cdd:PRK11131 1041 VDEKDSVAIKLFDTELEQQQAMWQGLRRLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLDLIDDCIACGVDKLIDEN 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 1125 GGPVWSEAGFAQLHDKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMSGLVYRGFVTGNGYK 1204
Cdd:PRK11131 1121 GGPVWTEEGFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALALSDIKAQMGGLVYRGFVTGNGWK 1200
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 1205 RLGDTLRYLNAIEKRLEKMAVDPHRDRAQMLKVEAVQQAWQQWLNKLPPARRDDDDVQEIRWMIEELRVSYFAQQLGTPY 1284
Cdd:PRK11131 1201 RLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVESVQQAWQQWLNKLPPARREDEDVKEIRWMIEELRVSYFAQQLGTPY 1280
|
1290
....*....|....
gi 1358765783 1285 PVSDKRVLQAMEQV 1298
Cdd:PRK11131 1281 PISDKRILQAMEQI 1294
|
|
| DEAH_box_HrpA |
TIGR01967 |
RNA helicase HrpA; This model represents HrpA, one of two related but uncharacterized DEAH-box ... |
12-1297 |
0e+00 |
|
RNA helicase HrpA; This model represents HrpA, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria and a few high-GC Gram-positive bacteria. HrpA is about 1300 amino acids long, while its paralog HrpB, also uncharacterized, is about 800 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. The HrpA/B homolog from Borrelia is 500 amino acids shorter but appears to be derived from HrpA rather than HrpB. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273900 [Multi-domain] Cd Length: 1283 Bit Score: 2250.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 12 LMARLDSLMLRDKSRFARRLHGAKKIKNTESQQALFEQLSQEMSEAAGKVLLREAARPAITYPENLPVSQKKQDILNAVR 91
Cdd:TIGR01967 1 LAEDLDHTMIRDRHRLRRRLHKLRKDHDQDRAIAALAKFRERIDAACDKVEARRQAVPEIRYPDNLPVSAKREDIAEAIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 92 DHQVVIVAGETGSGKTTQLPKICMELGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGYKVRFSDHVSDNTMVK 171
Cdd:TIGR01967 81 ENQVVIIAGETGSGKTTQLPKICLELGRGSHGLIGHTQPRRLAARTVAQRIAEELGTPLGEKVGYKVRFHDQVSSNTLVK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 172 LMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDPERFSRHFNNAPIIEVSG 251
Cdd:TIGR01967 161 LMTDGILLAETQQDRFLSRYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKIIITSATIDPERFSRHFNNAPIIEVSG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 252 RTYPVEVRYRPIVEEADDTERDQLQAIFDAVEELGREGPGDILIFMSGEREIRDTADGLMKLNLPHTEVLPLYARLSNSE 331
Cdd:TIGR01967 241 RTYPVEVRYRPLVEEQEDDDLDQLEAILDAVDELFAEGPGDILIFLPGEREIRDAAEILRKRNLRHTEILPLYARLSNKE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 332 QNRVFQPHAGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPVSQASANQRKGRCGRVSEGICIRL 411
Cdd:TIGR01967 321 QQRVFQPHSGRRIVLATNVAETSLTVPGIHYVIDTGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVAPGICIRL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 412 YSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDAQAsvYKLTPLGR 491
Cdd:TIGR01967 401 YSEEDFNSRPEFTDPEILRTNLASVILQMLALRLGDIAAFPFIEAPDPRAIRDGFRLLEELGALDDDEAE--PQLTPIGR 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 492 QLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRERPLDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKA 571
Cdd:TIGR01967 479 QLAQLPVDPRLARMLLEAHRLGCLQEVLIIASALSIQDPRERPMEKQQAADQAHARFKDPRSDFLSRVNLWRHIEEQRQA 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 572 LSSNQFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAGYREVHTALLTGLLSHIGMKDAdKQEYTGARNAR 651
Cdd:TIGR01967 559 LSANQFRNACRKQYLNYLRVREWQDIYRQLTQVVKELGLKLNEEPADYDAIHKALLSGLLSQIGMKDE-KHEYDGARGRK 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 652 FSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWIEPVAQHLIKRSYSEPHWERAQGAVMASEKVTLYGLPIVA 731
Cdd:TIGR01967 638 FHIFPGSPLFKKPPKWVMAAELVETSKLYARLVAKIEPEWVEPVAGHLIKKNYFEPHWEKKRGQVMAYEKVTLYGLTLVA 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 732 ARSVNYSQIDPVLSRELFIRHALVEGDWQTRHAFFRENQKLRAEVEELEHKSRRRDILVDDDTLFEFYDQRISVDAISAR 811
Cdd:TIGR01967 718 RRSVPYGPIDPADAREMFIRHALVEGEWQTRAAFFQANRALLEEVEELEHKARRRDILVDEQTLFDFYDGRLPEDINNAR 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 812 HFDSWWKKASRETPDLLNFEKSMLIKEGAEKVSKLDYPNFWHQGNLKLRLTYQFEPGGDADGVTVHIPLPLLNQVEDAGF 891
Cdd:TIGR01967 798 HFDSWWKKASRKQPDLLDFPKEVLFQRRANVISAAQFPDHWHKGDLRLALSYHFEPGHGDDGVTVHIPLPLLNQLDTEDF 877
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 892 EWQVPGMRRELIIALIKSLPKPVRRNFVPAPNYAEAFLGRVTPLELPLLDALERELRRMTGVTIDREAWQAEQVPDHLKM 971
Cdd:TIGR01967 878 DWLVPGLREEKVVALIKSLPKALRRNFVPAPDFAKACLARLPPNQGPLTDALARELRRMTGERVNPEDWDWEQLPDHLQM 957
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 972 TFRVVDEKGRKLREGKDLHALKEGLKEKVQETLSAVADDGIEQSGLHIWSFGTLPERYEQKRGGYQVKAFPALVDEKESV 1051
Cdd:TIGR01967 958 NFRIVDDKGKVLAQGRDLALLKERLAGDVRAALSAVADVGIEKSGLTNWSFGPLPERMEQKTGNYKVTAYPALVDDGGSV 1037
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 1052 GIRLFDNPQEQQHAMWRGQRRLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLDLIDDCISCGVDKLIAENGGPVWSE 1131
Cdd:TIGR01967 1038 AIKLFDTQAEAEAAHRAGLRRLLLLQIPSPVKMLQGKLPNKAKLALYYNPLGRVEVLVDDILHAAVDRLIFENGGQVRTQ 1117
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 1132 AGFAQLHDKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMSGLVYRGFVTGNGYKRLGDTLR 1211
Cdd:TIGR01967 1118 ADFAALLAQVRAELAPEVERIAKQLEEILVLFGNIRKRLKGKIDPTQAKALSDIKAQLDKLVYQGFVRTTGPQRLSHLPR 1197
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 1212 YLNAIEKRLEKMAVDPHRDRAQMLKVEAVQQAWQQWLNKLPPARRDDDDVQEIRWMIEELRVSYFAQQLGTPYPVSDKRV 1291
Cdd:TIGR01967 1198 YLKAMELRLEKLRVDPGRDRERQAEISNVQEAYDARLAKLPHERRLPAALVEIRWMIEEYRVSLFAQQLGTAYPISDKRI 1277
|
....*.
gi 1358765783 1292 LQAMEQ 1297
Cdd:TIGR01967 1278 LKYYRQ 1283
|
|
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
69-920 |
0e+00 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 1148.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 69 PAITYPENLPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVKGLIGHTQPRRLAARTVANRIAEELQT 148
Cdd:COG1643 2 SLITYPPDLPVSAVLPELLAALRAHQVVVLAAPPGAGKTTQLPLALLELGWGAGGRIGMLEPRRLAARAAAERMAEELGE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 149 EPGGCVGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPK-RPDLKVII 227
Cdd:COG1643 82 PVGETVGYRVRFEDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADLLLALLLDLQPAlRPDLKLLV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 228 TSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEaddtERDQLQAIFDAVEELGREGPGDILIFMSGEREIRDTA 307
Cdd:COG1643 162 MSATLDAERFARLLGDAPVIESSGRTYPVEVRYRPLPAD----ERDLEDAVADAVREALAEEPGDILVFLPGEREIRRTA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 308 DGLMKLNLPHTEVLPLYARLSNSEQNRVFQP--HAGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPI 385
Cdd:COG1643 238 EALRGRLPPDTEILPLYGRLSAAEQDRAFAPapHGRRRIVLATNIAETSLTVPGIRYVIDSGLARIPRYDPRSGVTRLPT 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 386 EPVSQASANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDG 465
Cdd:COG1643 318 ERISQASANQRAGRAGRLAPGICYRLWSEEDFARRPAFTDPEILRADLASLILELAAWGLGDPEDLPFLDPPPARAIADA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 466 VRLLEELGAITTDaqasvYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRerpldKQQASdekh 545
Cdd:COG1643 398 RALLQELGALDAD-----GRLTPLGRALARLPLDPRLARMLLAAAELGCLREAAILAALLSERDPR-----RGAAG---- 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 546 rrfhdkeSDFLAFVNLWNYLGEQQKAlssnqfrrlcrtdYLNYLRVREWQDIYTQLRQVVKElgiPVNSEPAGYREVHTA 625
Cdd:COG1643 464 -------SDLLARLNLWRRLREQQRE-------------FLSYLRLREWRDLARQLRRLLGE---GANEEPADYEAIGLL 520
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 626 LLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPpkWVMVAELVETSR-LWGRIAARIDPEWIEPVAQHLIKRsY 704
Cdd:COG1643 521 LALAYPDRIARRRGEGGRYLLARGRGAALFPGSPLAKKE--WLVAAELVGGAAeARIRLAAPIDPEWLEELAAHLIKR-Y 597
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 705 SEPHWERAQGAVMASEKVTLYGLPIVAARSvnySQIDPVLSRELFIRHALVEGDwqTRHAFFRENQKLRAEVEELEHKS- 783
Cdd:COG1643 598 SEPHWDKKRGRVVARERVRLGALVLVSRPL---PGPDPEAAREALLRALRREGL--DLLPWSKAARQLRARVEFLERKLg 672
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 784 -RRRDilVDDDTLfefydqrisvdaisARHFDSWWKKASRETPDLLNFEKSMLIKE-----GAEKVSKLD--YPNFWHQ- 854
Cdd:COG1643 673 eRWPD--VSDEAL--------------LATLEDWLAPYLTGVRSLKDLKRLDLLAAlrallPWEQQQRLDelAPTHLTVp 736
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 855 GNLKLRLTYQFEPG----------------GDADGvTVHIPLPLLNQVED-AGFEWQVPGMRRELIIALIKSLPKPVRRN 917
Cdd:COG1643 737 SGSRLPLDYSADGPpvavrlqelfglaetpGVADG-RVPVPLHLLSPAGRpLQVTWDLPGFWRGSYAEVRKELRGRYPKH 815
|
...
gi 1358765783 918 FVP 920
Cdd:COG1643 816 PWP 818
|
|
| DUF3418 |
pfam11898 |
Domain of unknown function (DUF3418); This presumed domain is functionally uncharacterized. ... |
713-1295 |
0e+00 |
|
Domain of unknown function (DUF3418); This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is typically between 582 to 594 amino acids in length. This domain is found associated with pfam07717, pfam00271, pfam04408.
Pssm-ID: 463389 Cd Length: 587 Bit Score: 938.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 713 QGAVMASEKVTLYGLPIVAARSVNYSQIDPVLSRELFIRHALVEGDWQTRHAFFRENQKLRAEVEELEHKSRRRDILVDD 792
Cdd:pfam11898 2 RGAVMAYERVTLYGLPIVARRRVNYGRIDPEEAREIFIRHALVEGEWRTRHTFFAHNRKLLEEVEELEHKARRRDILVDD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 793 DTLFEFYDQRISVDAISARHFDSWWKKASRETPDLLNFEKSMLIKEGAEKVSKLDYPNFWHQGNLKLRLTYQFEPGGDAD 872
Cdd:pfam11898 82 ETLFDFYDARLPADVVSGRHFDKWWKKARREDPDLLDLTREDLLRHEADAVTEEDFPDTWGLGGLRLPLSYRFEPGAEDD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 873 GVTVHIPLPLLNQVEDAGFEWQVPGMRRELIIALIKSLPKPVRRNFVPAPNYAEAFLGRV---TPLELPLLDALERELRR 949
Cdd:pfam11898 162 GVTVTVPLALLNQVSPERFDWLVPGLLEEKVTALIKSLPKALRRNFVPAPDFARAALARLerePPGDGPLLDALARALRR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 950 MTGVTIDREAWQAEQVPDHLKMTFRVVDEKGRKLREGKDLHALKEGLKEKVQETLSAVADDGIEQSGLHIWSFGTLPERY 1029
Cdd:pfam11898 242 LTGVRVPPDDWDLDALPPHLRMNFRVVDDRGKVLAEGRDLAALKARLAGQARAAFAAAAAASLERTGLTSWDFGDLPETV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 1030 EQKRGGYQVKAFPALVDEKESVGIRLFDNPQEQQHAMWRGQRRLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLDLI 1109
Cdd:pfam11898 322 ELKRGGQEVTGYPALVDEGDSVALRLFDTPAEAAAAHRAGVRRLLLLALPSPVKYLEKNLPNLQKLALAYNPLGSVEALV 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 1110 DDCISCGVDKLIAENGGPVWSEAGFAQLHDKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQM 1189
Cdd:pfam11898 402 DDLIAAALDRLFLEPVPLPRDEAAFEALLEEVRARLPDTAQEVARLVEEILAAYQALRKRLKGKKSLALAAALADIRAQL 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 1190 SGLVYRGFVTGNGYKRLGDTLRYLNAIEKRLEKMAVDPHRDRAQMLKVEAVQQAWQQWLNKLPPARRDDDDVQEIRWMIE 1269
Cdd:pfam11898 482 DRLVPPGFVAATPWERLAHLPRYLKAIELRLEKLPADPARDRQRMAEVAPLEQRYQALLAKLPAGRPDPEELEEFRWMLE 561
|
570 580
....*....|....*....|....*.
gi 1358765783 1270 ELRVSYFAQQLGTPYPVSDKRVLQAM 1295
Cdd:pfam11898 562 ELRVSLFAQELGTPYPVSEKRLEKAW 587
|
|
| DEXHc_HrpA |
cd17989 |
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ... |
77-249 |
3.65e-116 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350747 [Multi-domain] Cd Length: 173 Bit Score: 359.46 E-value: 3.65e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGY 156
Cdd:cd17989 1 LPVSQKRDEIAKAIAENQVVIIAGETGSGKTTQLPKICLELGRGIRGLIGHTQPRRLAARSVAERIAEELKTELGGAVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 157 KVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDPER 236
Cdd:cd17989 81 KVRFTDQTSDETCVKLMTDGILLAETQTDRYLRAYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATIDAER 160
|
170
....*....|...
gi 1358765783 237 FSRHFNNAPIIEV 249
Cdd:cd17989 161 FSRHFNNAPIIEV 173
|
|
| DEAH_box_HrpB |
TIGR01970 |
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but ... |
77-574 |
2.16e-101 |
|
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273901 [Multi-domain] Cd Length: 819 Bit Score: 342.13 E-value: 2.16e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGrGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGY 156
Cdd:TIGR01970 1 LPIHAVLPALRDALAAHPQVVLEAPPGAGKSTAVPLALLDAP-GIGGKIIMLEPRRLAARSAAQRLASQLGEAVGQTVGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 157 KVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPK-RPDLKVIITSATIDPE 235
Cdd:TIGR01970 80 RVRGENKVSRRTRLEVVTEGILTRMIQDDPELDGVGALIFDEFHERSLDADLGLALALDVQSSlREDLKILAMSATLDGE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 236 RFSRHFNNAPIIEVSGRTYPVEVRYRPIveEADDTERDQLQaifDAVEELGREGPGDILIFMSGEREIRDTADGLMKLNL 315
Cdd:TIGR01970 160 RLSSLLPDAPVVESEGRSFPVEIRYLPL--RGDQRLEDAVS---RAVEHALASETGSILVFLPGQAEIRRVQEQLAERLD 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 316 PHTEVLPLYARLSNSEQNRVFQPHAG--RRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPVSQASA 393
Cdd:TIGR01970 235 SDVLICPLYGELSLAAQDRAIKPDPQgrRKVVLATNIAETSLTIEGIRVVIDSGLARVARFDPKTGITRLETVRISQASA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 394 NQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELG 473
Cdd:TIGR01970 315 TQRAGRAGRLEPGVCYRLWSEEQHQRLPAQDEPEILQADLSGLALELAQWGAKDPSDLRWLDAPPSVALAAARQLLQRLG 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 474 AIttDAQAsvyKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQD-PRERPLDKQQASDEKHRRFHDKE 552
Cdd:TIGR01970 395 AL--DAQG---RLTAHGKAMAALGCHPRLAAMLLSAHSTGLAALACDLAALLEERGlPRQGGADLMNRLHRLQQGRQGRG 469
|
490 500
....*....|....*....|..
gi 1358765783 553 SDFLAFVNLWNYLGEQQKALSS 574
Cdd:TIGR01970 470 QRAQQLAKKLRRRLRFSQADSG 491
|
|
| PRK11664 |
PRK11664 |
ATP-dependent RNA helicase HrpB; Provisional |
77-525 |
5.84e-99 |
|
ATP-dependent RNA helicase HrpB; Provisional
Pssm-ID: 236950 [Multi-domain] Cd Length: 812 Bit Score: 335.36 E-value: 5.84e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPkicMEL--GRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCV 154
Cdd:PRK11664 4 LPVAAVLPELLTALKTAPQVLLKAPTGAGKSTWLP---LQLlqHGGINGKIIMLEPRRLAARNVAQRLAEQLGEKPGETV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 155 GYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLREL---LpkRPDLKVIITSAT 231
Cdd:PRK11664 81 GYRMRAESKVGPNTRLEVVTEGILTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVqqgL--RDDLKLLIMSAT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 232 IDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIveeaddTERDQL-QAIFDAVEELGREGPGDILIFMSGEREIRDTADGL 310
Cdd:PRK11664 159 LDNDRLQQLLPDAPVIVSEGRSFPVERRYQPL------PAHQRFdEAVARATAELLRQESGSLLLFLPGVGEIQRVQEQL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 311 MKLNLPHTEVLPLYARLSNSEQNRVFQPH-AGRR-IVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPV 388
Cdd:PRK11664 233 ASRVASDVLLCPLYGALSLAEQQKAILPApAGRRkVVLATNIAETSLTIEGIRLVVDSGLERVARFDPKTGLTRLVTQRI 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 389 SQASANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRL 468
Cdd:PRK11664 313 SQASMTQRAGRAGRLEPGICLHLYSKEQAERAAAQSEPEILHSDLSGLLLELLQWGCHDPAQLSWLDQPPAAALAAAKRL 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1358765783 469 LEELGAITTDAQasvykLTPLGRQLSQLPVDPRLARMVLEAQKHGcvrEAMIITSAL 525
Cdd:PRK11664 393 LQQLGALDGQGR-----LTARGRKMAALGNDPRLAAMLVAAKEDD---EAALATAAK 441
|
|
| DEXHc_RHA-like |
cd17917 |
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ... |
93-249 |
5.10e-79 |
|
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438707 [Multi-domain] Cd Length: 159 Bit Score: 256.62 E-value: 5.10e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 93 HQVVIVAGETGSGKTTQLPKICME--LGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGYKVRFSDHVSDNTMV 170
Cdd:cd17917 1 NQVVVIVGETGSGKTTQVPQFLLEdgLAKGGKGRIVCTQPRRIAAISVAERVAEERGEKLGEEVGYQIRFESKTSSKTRI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1358765783 171 KLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDPERFSRHFNNAPIIEV 249
Cdd:cd17917 81 KFCTDGILLRELLSDPLLSGYSHVILDEAHERSLDTDFLLGLLKDLLRKRPDLKVILMSATLDAEKFSSYFGGAPVIHI 159
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
254-412 |
3.61e-63 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 212.39 E-value: 3.61e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 254 YPVEVRYRPIVEEA-----DDTERDQLQAIFDAVEEL-GREGPGDILIFMSGEREIRDTADGLMKL----NLPHTEVLPL 323
Cdd:cd18791 1 FPVEVYYLEDILELlgissEKEDPDYVDAAVRLILQIhRTEEPGDILVFLPGQEEIERLCELLREEllspDLGKLLVLPL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 324 YARLSNSEQNRVFQPHAG--RRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPVSQASANQRKGRCG 401
Cdd:cd18791 81 HSSLPPEEQQRVFEPPPPgvRKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISKASAEQRAGRAG 160
|
170
....*....|.
gi 1358765783 402 RVSEGICIRLY 412
Cdd:cd18791 161 RTRPGKCYRLY 171
|
|
| DEXHc_DHX33 |
cd17978 |
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ... |
77-247 |
7.33e-63 |
|
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438710 [Multi-domain] Cd Length: 178 Bit Score: 211.83 E-value: 7.33e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGY 156
Cdd:cd17978 1 LPIYSARKRLLEELRKHDTVIIIGETGSGKTTQIPQYLYEAGFARGGMIGITQPRRVAAVSVAKRVAEEMGVELGQLVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 157 KVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYL-----RELLPKRPDLKVIITSAT 231
Cdd:cd17978 81 SVRFDDVTSEETRIKYMTDGMLLREAIGDPLLSKYSVIILDEAHERTVHTDVLFGLVksaqrRRKEQKLSPLKVIIMSAT 160
|
170
....*....|....*.
gi 1358765783 232 IDPERFSRHFNNAPII 247
Cdd:cd17978 161 LDADLFSEYFNGAPVL 176
|
|
| DEXHc_DHX38 |
cd17983 |
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as ... |
77-249 |
5.11e-62 |
|
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as PRP16) is involved in pre-mRNA splicing. DHX38 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350741 [Multi-domain] Cd Length: 173 Bit Score: 209.24 E-value: 5.11e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGY 156
Cdd:cd17983 1 LPIFAVRQELLNVIRDNNVVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGVELGEEVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 157 KVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDPER 236
Cdd:cd17983 81 AIRFEDCTSENTVIKYMTDGILLRESLRDPDLDKYSAIIMDEAHERSLNTDVLFGLLREVVARRRDLKLIVTSATMDADK 160
|
170
....*....|...
gi 1358765783 237 FSRHFNNAPIIEV 249
Cdd:cd17983 161 FADFFGNVPIFTI 173
|
|
| DEXHc_DHX8 |
cd17971 |
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as ... |
75-249 |
3.98e-61 |
|
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22) acts late in the splicing of pre-mRNA and mediates the release of the spliced mRNA from spliceosomes. DHX8 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350729 [Multi-domain] Cd Length: 179 Bit Score: 206.95 E-value: 3.98e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 75 ENLPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCV 154
Cdd:cd17971 4 ESLPIYKLKEQLIQAVHDNQILVVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVAEEFGCCLGQEV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 155 GYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDP 234
Cdd:cd17971 84 GYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLSQYSVIMLDEAHERTIHTDVLFGLLKKTVQKRPDLKLIVTSATLDA 163
|
170
....*....|....*
gi 1358765783 235 ERFSRHFNNAPIIEV 249
Cdd:cd17971 164 VKFSQYFYEAPIFTI 178
|
|
| DEXHc_DHX15 |
cd17973 |
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ... |
77-249 |
1.77e-60 |
|
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438709 [Multi-domain] Cd Length: 187 Bit Score: 205.34 E-value: 1.77e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICME--LGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCV 154
Cdd:cd17973 13 LPVWEQKEDFLKLLKNNQILVLVGETGSGKTTQIPQFVLDdeLPHQPKKLVACTQPRRVAAMSVAQRVAEEMDVKLGEEV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 155 GYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDP 234
Cdd:cd17973 93 GYSIRFEDCSSAKTILKYMTDGMLLREAMSDPLLSRYSVIILDEAHERTLATDILMGLLKEVVRRRPDLKLIVMSATLDA 172
|
170
....*....|....*
gi 1358765783 235 ERFSRHFNNAPIIEV 249
Cdd:cd17973 173 GKFQKYFDNAPLLKV 187
|
|
| DEXHc_DHX16 |
cd17974 |
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably ... |
77-249 |
2.12e-57 |
|
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably involved in pre-mRNA splicing. DHX16 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350732 [Multi-domain] Cd Length: 174 Bit Score: 195.80 E-value: 2.12e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVKGL-IGHTQPRRLAARTVANRIAEELQTEPGGCVG 155
Cdd:cd17974 1 LPVYPYRDDLLAAVKEHQVLIIVGETGSGKTTQIPQYLHEAGYTKGGGkIGCTQPRRVAAMSVAARVAEEMGVKLGNEVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 156 YKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDPE 235
Cdd:cd17974 81 YSIRFEDCTSEKTVLKYMTDGMLLREFLTEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPDLKLLISSATMDAE 160
|
170
....*....|....
gi 1358765783 236 RFSRHFNNAPIIEV 249
Cdd:cd17974 161 KFSAFFDDAPIFRI 174
|
|
| DEXHc_DHX37 |
cd17982 |
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ... |
77-249 |
1.00e-55 |
|
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350740 [Multi-domain] Cd Length: 191 Bit Score: 191.80 E-value: 1.00e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVK-----GLIGHTQPRRLAARTVANRIAEELqTEPG 151
Cdd:cd17982 1 LPILAEEQEIMEAINENPVVIICGETGSGKTTQVPQFLYEAGFGSPesdnpGMIGITQPRRVAAVSMAKRVAEEL-NVFG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 152 GCVGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPD--------- 222
Cdd:cd17982 80 KEVSYQIRYDSTVSENTKIKFMTDGVLLKEIQTDFLLRKYSVIIIDEAHERSVNTDILIGMLSRIVPLRAKlylqdqtvk 159
|
170 180 190
....*....|....*....|....*....|..
gi 1358765783 223 -LKVIITSATIDPERFS---RHFNNAP-IIEV 249
Cdd:cd17982 160 pLKLVIMSATLRVEDFTenkLLFPRPPpVIKV 191
|
|
| DEXHc_DHX40 |
cd17984 |
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ... |
77-249 |
1.67e-53 |
|
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350742 [Multi-domain] Cd Length: 178 Bit Score: 185.06 E-value: 1.67e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGY 156
Cdd:cd17984 1 LPIQKQRKKLVQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRRVAAISVAQRVAEEMKCTLGSKVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 157 KVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRP-----DLKVIITSAT 231
Cdd:cd17984 81 QVRFDDCSSKETAIKYMTDGCLLRHILADPNLTKYSVIILDEAHERSLTTDILFGLLKKLFQEKSpnrkeHLKVVVMSAT 160
|
170
....*....|....*...
gi 1358765783 232 IDPERFSRHFNNAPIIEV 249
Cdd:cd17984 161 LELAKLSAFFGNCPVFDI 178
|
|
| DEXHc_DHX34 |
cd17979 |
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in ... |
77-249 |
9.35e-53 |
|
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in the nonsense-mediated decay (NMD), a surveillance mechanism that degrades aberrant mRNAs. DHX34 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350737 [Multi-domain] Cd Length: 170 Bit Score: 182.64 E-value: 9.35e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVkglIGHTQPRRLAARTVANRIAEELQTEPGGCVGY 156
Cdd:cd17979 1 LPIAQYREKIIELLKTHQVVIVAGDTGCGKSTQVPQYLLAAGFRH---IACTQPRRIACISLAKRVAFESLNQYGSKVAY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 157 KVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDPER 236
Cdd:cd17979 78 QIRFERTRTLATKLLFLTEGLLLRQIQRDASLPQYNVLILDEVHERHLHGDFLLGVLRCLLRLRPDLKLILMSATINIEL 157
|
170
....*....|...
gi 1358765783 237 FSRHFNNAPIIEV 249
Cdd:cd17979 158 FSGYFEGAPVVQV 170
|
|
| DEXHc_DHX35 |
cd17980 |
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and ... |
77-242 |
7.33e-52 |
|
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and seems to be associated with risk to thyroid cancers. It also has been shown to positively regulate poxviruses, such as Myxoma virus. DEAH-box helicase 35 (DHX35) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350738 [Multi-domain] Cd Length: 185 Bit Score: 180.36 E-value: 7.33e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVKG-LIGHTQPRRLAARTVANRIAEELQTEPGGCVG 155
Cdd:cd17980 1 LPVFKLRNHILYLVENYQTIVIVGETGCGKSTQIPQYLAEAGWTAGGrVVGCTQPRRVAAVTVAGRVAEEMGAVLGHEVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 156 YKVRFSDHVSD-NTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDP 234
Cdd:cd17980 81 YCIRFDDCTDPqATRIKFLTDGMLVREMMLDPLLTKYSVIMLDEAHERTLYTDILIGLLKKIQKKRGDLRLIVASATLDA 160
|
....*...
gi 1358765783 235 ERFSRHFN 242
Cdd:cd17980 161 EKFRDFFN 168
|
|
| DEXHc_DHX29 |
cd17975 |
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of ... |
77-249 |
1.77e-47 |
|
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of the 43S pre-initiation complex involved in translation initiation of mRNAs with structured 5'-UTRs. DHX29 is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350733 [Multi-domain] Cd Length: 183 Bit Score: 167.78 E-value: 1.77e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICME-----LGRGVKGLIGHTQPRRLAARTVANRIAEELQTE-- 149
Cdd:cd17975 1 LPVFKHRESILETLKRHRVVVVAGETGSGKSTQVPQFLLEdlllnGGTAQKCNIVCTQPRRISAMSLATRVCEELGCEsg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 150 PGG---CVGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVI 226
Cdd:cd17975 81 PGGknsLCGYQIRMESRTGEATRLLYCTTGVLLRKLQEDGLLSSISHIIVDEVHERSVQSDFLLIILKEILHKRSDLHLI 160
|
170 180
....*....|....*....|...
gi 1358765783 227 ITSATIDPERFSRHFNNAPIIEV 249
Cdd:cd17975 161 LMSATVDCEKFSSYFTHCPILRI 183
|
|
| DEXHc_DHX36 |
cd17981 |
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as ... |
77-249 |
2.52e-44 |
|
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as G4-resolvase 1 or G4R1, MLE-like protein 1 and RNA helicase associated with AU-rich element or RHAU) unwinds a G4-quadruplex in human telomerase RNA. DHX36 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350739 [Multi-domain] Cd Length: 180 Bit Score: 158.85 E-value: 2.52e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKIC----MELGRGVKGLIGHTQPRRLAARTVANRIAEEL--QTEP 150
Cdd:cd17981 1 LPSYGMKQEIINMIDNNQVTVISGETGCGKTTQVTQFIlddaIERGKGSSCRIVCTQPRRISAISVAERVAAERaeSCGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 151 GGCVGYKVRFSDHVSDN-TMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITS 229
Cdd:cd17981 81 GNSTGYQIRLESRKPRKqGSILYCTTGIVLQWLQSDPHLSNVSHLVLDEIHERNLQSDVLMGIVKDLLPFRSDLKVILMS 160
|
170 180
....*....|....*....|
gi 1358765783 230 ATIDPERFSRHFNNAPIIEV 249
Cdd:cd17981 161 ATLNAEKFSDYFNNCPMIHI 180
|
|
| DEXHc_YTHDC2 |
cd17987 |
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) ... |
77-249 |
4.45e-44 |
|
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) regulates mRNA translation and stability via binding to N6-methyladenosine, a modified RNA nucleotide enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. YTHDC2 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350745 [Multi-domain] Cd Length: 176 Bit Score: 157.68 E-value: 4.45e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICME--LGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCV 154
Cdd:cd17987 1 LPVFEKQEQIVRIIKENKVVLIVGETGSGKTTQIPQFLLDdcYANGIPCRIFCTQPRRLAAIAVAERVAAERGEKIGQTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 155 GYKVRFSDHVSDNTMVKLMTDGILLAEIQQ-DRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATID 233
Cdd:cd17987 81 GYQIRLESRVSPKTLLTFCTNGVLLRTLMAgDSALSTVTHVIVDEVHERDRFSDFLLTKLRDILQKHPNLKLILSSAALD 160
|
170
....*....|....*.
gi 1358765783 234 PERFSRHFNNAPIIEV 249
Cdd:cd17987 161 VNLFIRYFGSCPVIYI 176
|
|
| DEXHc_DHX30 |
cd17976 |
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an ... |
77-249 |
1.60e-41 |
|
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an important role in the assembly of the mitochondrial large ribosomal subunit. DHX30 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350734 [Multi-domain] Cd Length: 178 Bit Score: 150.71 E-value: 1.60e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICME----LGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGG 152
Cdd:cd17976 1 LPVDSHKESILSAIEQNPVVVISGDTGCGKTTRIPQFILEdyvlRGRGARCNVVITQPRRISAVSVAQRVAHELGPNLRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 153 CVGYKVRF-SDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSAT 231
Cdd:cd17976 81 NVGYQVRLeSRPPPRGGALLFCTVGVLLKKLQSNPRLEGVSHVIVDEVHERDVNTDFLLILLKGVLQLNPELRVVLMSAT 160
|
170
....*....|....*...
gi 1358765783 232 IDPERFSRHFNNAPIIEV 249
Cdd:cd17976 161 GDNQRLSRYFGGCPVVRV 178
|
|
| DEXHc_HrpB |
cd17990 |
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ... |
77-249 |
2.43e-41 |
|
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438711 [Multi-domain] Cd Length: 174 Bit Score: 149.79 E-value: 2.43e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMELGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGY 156
Cdd:cd17990 1 LPIAAVLPALRAALDAGGQVVLEAPPGAGKTTRVPLALLAELWIAGGKIIVLEPRRVAARAAARRLATLLGEAPGETVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 157 KVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLP-KRPDLKVIITSATIDPE 235
Cdd:cd17990 81 RVRGESRVGRRTRVEVVTEGVLLRRLQRDPELSGVGAVILDEFHERSLDADLALALLLEVQQlLRDDLRLLAMSATLDGD 160
|
170
....*....|....
gi 1358765783 236 RFSRHFNNAPIIEV 249
Cdd:cd17990 161 GLAALLPEAPVVES 174
|
|
| DEXHc_DHX57 |
cd17985 |
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the ... |
77-249 |
3.64e-40 |
|
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350743 [Multi-domain] Cd Length: 177 Bit Score: 146.52 E-value: 3.64e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICME--LGRGVKGL--IGHTQPRRLAARTVANRIAEELQTEPGG 152
Cdd:cd17985 1 LPAWQERETILELLEKHQVLVISGMTGCGKTTQIPQFILDnsLQGPPLPVanIICTQPRRISAISVAERVAQERAERVGQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 153 CVGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATI 232
Cdd:cd17985 81 SVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDPTLQGVTHVIVDEVHERTEESDFLLLVLKDLMVQRPDLKVILMSATL 160
|
170
....*....|....*..
gi 1358765783 233 DPERFSRHFNNAPIIEV 249
Cdd:cd17985 161 NAELFSDYFNSCPVIHI 177
|
|
| DEXHc_DHX9 |
cd17972 |
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ... |
48-249 |
3.33e-39 |
|
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ATP-dependent RNA helicase A or RHA and leukophysin or LKP) plays an important role in many cellular processes, including regulation of DNA replication, transcription, translation, microRNA biogenesis, RNA processing and transport, and maintenance of genomic stability. DHX9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350730 [Multi-domain] Cd Length: 234 Bit Score: 146.13 E-value: 3.33e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 48 EQLSQE-MSEAAGKVLLREAARPAITYPENLPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMEL----GRGVK 122
Cdd:cd17972 29 EQISMDlKNELMYQREQDHNLQQILQERELLPVKKFREEILEAISNNPVVIIRGATGCGKTTQVPQYILDDfiqnDRAAE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 123 GLIGHTQPRRLAARTVANRIAEELQTEPGGCVGYKVRFsDHVSDNTMVKLM--TDGILLAEIQQDrlLMQYDTIIIDEAH 200
Cdd:cd17972 109 CNIVVTQPRRISAVSVAERVAFERGEEVGKSCGYSVRF-ESVLPRPHASILfcTVGVLLRKLEAG--IRGISHVIVDEIH 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1358765783 201 ERSLNIDFLLGYLRELLPKRPDLKVIITSATIDPERFSRHFNNAPIIEV 249
Cdd:cd17972 186 ERDINTDFLLVVLRDVVQAYPDLRVILMSATIDTSMFCEYFFNCPVIEV 234
|
|
| DEXHc_TDRD9 |
cd17988 |
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also ... |
77-249 |
2.44e-38 |
|
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also known as HIG-1or NET54 or C14orf75) is a part of the nuclear PIWI-interacting RNA (piRNA) pathway essential for transposon silencing and male fertility TDRD9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350746 [Multi-domain] Cd Length: 180 Bit Score: 141.49 E-value: 2.44e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICME--LGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCV 154
Cdd:cd17988 1 LPIYAKREEILSLIEANSVVIIKGATGCGKTTQLPQFILDhyYKRGKYCNIVVTQPRRIAAISIARRVSQEREWTLGSLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 155 GYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPD-LKVIITSATID 233
Cdd:cd17988 81 GYQVGLERPASEETRLIYCTTGVLLQKLINNKTLTEYTHIILDEVHERDQELDFLLLVVRRLLRTNSRhVKIILMSATIS 160
|
170 180
....*....|....*....|
gi 1358765783 234 PERFSRHF----NNAPIIEV 249
Cdd:cd17988 161 CKEFADYFttpnNPAYVFEV 180
|
|
| DEXHc_DHX32 |
cd17977 |
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the ... |
77-249 |
9.56e-33 |
|
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350735 [Multi-domain] Cd Length: 176 Bit Score: 125.32 E-value: 9.56e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 77 LPVSQKKQDILNAVRDHQVVIVAGETGSGKTTQLPKICMEL---GRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGC 153
Cdd:cd17977 1 LPVWEAKYEFMESLAHNQIVIVSGDAKTGKSSQIPQWCAEYclsAHYQHGVVVCTQVHKQTAVWLALRVADEMDVNIGHE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 154 VGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATID 233
Cdd:cd17977 81 VGYVIPFENCCTNETILRYCTDDMLLREMMSDPLLESYGVIILDDAHERTVSTDVLLGLLKDVLLSRPELKLVIITCPHL 160
|
170
....*....|....*.
gi 1358765783 234 PERFSRHFNNAPIIEV 249
Cdd:cd17977 161 SSKLLSYYGNVPLIEV 176
|
|
| DEXQc_DQX1 |
cd17986 |
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 ... |
95-249 |
1.68e-30 |
|
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 (DQX1) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350744 [Multi-domain] Cd Length: 177 Bit Score: 118.85 E-value: 1.68e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 95 VVIVAGETGSGKTTQLPKICME--LGRGV-KGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGYKVRFSDHVSDNTMVK 171
Cdd:cd17986 20 IVLVSGEPGSGKSTQVPQWCAEfaLSRGFqKGQVTVTQPHPLAARSLALRVADEMDLNLGHEVGYSIPQEDCTGPNTILR 99
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1358765783 172 LMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLPKRPDLKVIITSATIDPERFSRHFNNAPIIEV 249
Cdd:cd17986 100 FCWDRLLLQEMTSTPLLGAWGVVVLDEAQERSVASDSLLGLLKDVRLQRPELRVVVVTSPALEPKLRAFWGNPPVVHV 177
|
|
| HA2 |
smart00847 |
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino ... |
471-559 |
1.62e-26 |
|
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 214852 [Multi-domain] Cd Length: 82 Bit Score: 103.89 E-value: 1.62e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 471 ELGAITTDAQasvykLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRERplDKQQASDEKHRRFHD 550
Cdd:smart00847 1 ELGALDDDGR-----LTPLGRKMAELPLDPRLAKMLLAAAEFGCLDEILTIVAMLSVGDPRPK--EKREDADAARRRFAD 73
|
....*....
gi 1358765783 551 KESDFLAFV 559
Cdd:smart00847 74 PESDHLTLL 82
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
89-261 |
4.47e-23 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 98.33 E-value: 4.47e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 89 AVRDHQVVIVAGETGSGKTTQLPKICME-LGRGVKGLIGHTQPRRLAARTVANRIAEELQTEPGGCVGY------KVRFS 161
Cdd:smart00487 20 LLSGLRDVILAAPTGSGKTLAALLPALEaLKRGKGGRVLVLVPTRELAEQWAEELKKLGPSLGLKVVGLyggdskREQLR 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 162 DHVSDNTMVKLMTDGILLAEIQQDRL-LMQYDTIIIDEAHERS--LNIDFLLGYLRELlpkRPDLKVIITSATI--DPER 236
Cdd:smart00487 100 KLESGKTDILVTTPGRLLDLLENDKLsLSNVDLVILDEAHRLLdgGFGDQLEKLLKLL---PKNVQLLLLSATPpeEIEN 176
|
170 180
....*....|....*....|....*
gi 1358765783 237 FSRHFNNAPIIEVSGRTYPVEVRYR 261
Cdd:smart00487 177 LLELFLNDPVFIDVGFTPLEPIEQF 201
|
|
| HA2 |
pfam04408 |
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in ... |
466-558 |
5.88e-21 |
|
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 461295 [Multi-domain] Cd Length: 104 Bit Score: 88.83 E-value: 5.88e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 466 VRLLEELGAITTDAQasvykLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRERPLDKQQASDEKH 545
Cdd:pfam04408 2 LELLYYLGALDEDGE-----LTPLGRKMAELPLDPRLAKMLLAAAELGCLDEVLTIVAALSVRDPFVQPNFLDPRSAAKA 76
|
90 100
....*....|....*....|....*...
gi 1358765783 546 RR---------------FHDKESDFLAF 558
Cdd:pfam04408 77 ARrrrraadekarakfaRLDLEGDHLTL 104
|
|
| OB_NTP_bind |
pfam07717 |
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus ... |
622-699 |
2.97e-17 |
|
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus of the DEAD-box helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. There do seem to be a couple of instances where it occurs by itself -. The structure PDB:3i4u adopts an OB-fold. helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. This C-terminal domain of the yeast helicase contains an oligonucleotide/oligosaccharide-binding (OB)-fold which seems to be placed at the entrance of the putative nucleic acid cavity. It also constitutes the binding site for the G-patch-containing domain of Pfa1p. When found on DEAH/RHA helicases, this domain is central to the regulation of the helicase activity through its binding of both RNA and G-patch domain proteins.
Pssm-ID: 400182 [Multi-domain] Cd Length: 82 Bit Score: 77.68 E-value: 2.97e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 622 VHTALLTGLLSHIGMKDADKQEYTGAR-NARFSIFPGSGLF---KKPPKWVMVAELVETSRLWGRIAARIDPEWIEPVAQ 697
Cdd:pfam07717 1 LRAALAAGLYPNVARRDPKGKGYTTLSdNQRVFIHPSSVLFnekTFPPEWVVYQELVETTKVYIRTVTAISPEWLLLFAP 80
|
..
gi 1358765783 698 HL 699
Cdd:pfam07717 81 HI 82
|
|
| PHA02653 |
PHA02653 |
RNA helicase NPH-II; Provisional |
78-415 |
8.04e-14 |
|
RNA helicase NPH-II; Provisional
Pssm-ID: 177443 [Multi-domain] Cd Length: 675 Bit Score: 76.17 E-value: 8.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 78 PVSQKKqdILNAVRDHQVVIVAGETGSGKTTQLPKICM---ELGRGVKGL-----------IGHTQPR----RLAARTVA 139
Cdd:PHA02653 166 PDVQLK--IFEAWISRKPVVLTGGTGVGKTSQVPKLLLwfnYLFGGFDNLdkidpnfierpIVLSLPRvalvRLHSITLL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 140 NRIA-EELQTEPggcvgYKVRFSDHVSDNTMVKLMTDGILLAeiqQDRL----LMQYDTIIIDEAHERSLNIDFLLGYLR 214
Cdd:PHA02653 244 KSLGfDEIDGSP-----ISLKYGSIPDELINTNPKPYGLVFS---THKLtlnkLFDYGTVIIDEVHEHDQIGDIIIAVAR 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 215 ELLPKRPDLkvIITSATI--DPERFSRHFNNAPIIEVSGRT-YPV-EV----RYRPI--VEEADDTERDQLQAIFDAVEE 284
Cdd:PHA02653 316 KHIDKIRSL--FLMTATLedDRDRIKEFFPNPAFVHIPGGTlFPIsEVyvknKYNPKnkRAYIEEEKKNIVTALKKYTPP 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 285 LGREGpgdiLIFMSGEREIRDTADGL------MKLNLPHTEVLPLYARLSNSEQNRvfQPHagrrIVLATNVAETSLTVP 358
Cdd:PHA02653 394 KGSSG----IVFVASVSQCEEYKKYLekrlpiYDFYIIHGKVPNIDEILEKVYSSK--NPS----IIISTPYLESSVTIR 463
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1358765783 359 GIKYVIDpgTARISRYSYRTKVQRLpiepVSQASANQRKGRCGRVSEGICIRLYSED 415
Cdd:PHA02653 464 NATHVYD--TGRVYVPEPFGGKEMF----ISKSMRTQRKGRVGRVSPGTYVYFYDLD 514
|
|
| HELICc |
smart00490 |
helicase superfamily c-terminal domain; |
311-402 |
9.96e-10 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 56.45 E-value: 9.96e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 311 MKLNLPHTEVLPLYARLSNSEQNRVFQ--PHAGRRIVLATNVAETSLTVPGIKYVIDPGTarisrysyrtkvqrlpiePV 388
Cdd:smart00490 5 ELLKELGIKVARLHGGLSQEEREEILDkfNNGKIKVLVATDVAERGLDLPGVDLVIIYDL------------------PW 66
|
90
....*....|....
gi 1358765783 389 SQASANQRKGRCGR 402
Cdd:smart00490 67 SPASYIQRIGRAGR 80
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
282-403 |
4.36e-09 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 55.29 E-value: 4.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 282 VEELGREGPGDILIFMSGereiRDTADGLMKLNLPHTEVLPLYARLSNSEQNRVFQ--PHAGRRIVLATNVAETSLTVPG 359
Cdd:pfam00271 7 LELLKKERGGKVLIFSQT----KKTLEAELLLEKEGIKVARLHGDLSQEEREEILEdfRKGKIDVLVATDVAERGLDLPD 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1358765783 360 IKYVIDpgtarisrYSYrtkvqrlpiePVSQASANQRKGRCGRV 403
Cdd:pfam00271 83 VDLVIN--------YDL----------PWNPASYIQRIGRAGRA 108
|
|
| BRR2 |
COG1204 |
Replicative superfamily II helicase [Replication, recombination and repair]; |
86-509 |
7.21e-09 |
|
Replicative superfamily II helicase [Replication, recombination and repair];
Pssm-ID: 440817 [Multi-domain] Cd Length: 529 Bit Score: 59.91 E-value: 7.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 86 ILNAVRDHQVVIVAGETGSGKTT--QLPkICMELGRGVKGLIghtqprrLAA-RTVANRIAEELQT--EPGGcVGYKVRF 160
Cdd:COG1204 31 LEAGLLEGKNLVVSAPTASGKTLiaELA-ILKALLNGGKALY-------IVPlRALASEKYREFKRdfEELG-IKVGVST 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 161 SDHVSDNTMVK-----LMT----DGILLAEIqqdRLLMQYDTIIIDEAH-----ERSLNIDFLLGYLRELlpkRPDLKVI 226
Cdd:COG1204 102 GDYDSDDEWLGrydilVATpeklDSLLRNGP---SWLRDVDLVVVDEAHliddeSRGPTLEVLLARLRRL---NPEAQIV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 227 ITSATID-PERFSRHFnNAPIIEVSGRtyPVE----VRYRPIVEEADDTERdQLQAIFDAVEELGREGpGDILIFMSGER 301
Cdd:COG1204 176 ALSATIGnAEEIAEWL-DAELVKSDWR--PVPlnegVLYDGVLRFDDGSRR-SKDPTLALALDLLEEG-GQVLVFVSSRR 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 302 EIRDTADGLMK-----LNLPHTEVLPLYA--------------RLSNSEQNRVFQPHAG-----RRIV------------ 345
Cdd:COG1204 251 DAESLAKKLADelkrrLTPEEREELEELAeellevseethtneKLADCLEKGVAFHHAGlpselRRLVedafreglikvl 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 346 LATnvaeTSLT----VPgIKYVIdpgtarISRYsYRTKVQRLPIEPVSQASanqrkGRCGRVS-----EGICIRLYSEDD 416
Cdd:COG1204 331 VAT----PTLAagvnLP-ARRVI------IRDT-KRGGMVPIPVLEFKQMA-----GRAGRPGydpygEAILVAKSSDEA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 417 -------FLSRPE-----FTDPEILRTNLASVILQMTALGLGDIAAF--------PFVEAPDKRNIQDGVRLLEELGAIT 476
Cdd:COG1204 394 delferyILGEPEpirskLANESALRTHLLALIASGFANSREELLDFlentfyayQYDKGDLEEVVDDALEFLLENGFIE 473
|
490 500 510
....*....|....*....|....*....|...
gi 1358765783 477 TDaqASVYKLTPLGRQLSQLPVDPRLARMVLEA 509
Cdd:COG1204 474 ED--GDRLRATKLGKLVSRLYIDPLTAAELVDG 504
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
96-235 |
1.10e-06 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 49.93 E-value: 1.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 96 VIVAGETGSGKTT--QLP--KICMELGRGVKGLIghTQPRR-LAartvaNRIAEELQtEPGGCVGYKVR--FSDHVSDNT 168
Cdd:pfam00270 17 VLVQAPTGSGKTLafLLPalEALDKLDNGPQALV--LAPTReLA-----EQIYEELK-KLGKGLGLKVAslLGGDSRKEQ 88
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1358765783 169 MVKL-------MTDGILLAEIQQDRLLMQYDTIIIDEAHeRSLNIDF--LLGYLRELLPkrPDLKVIITSATIDPE 235
Cdd:pfam00270 89 LEKLkgpdilvGTPGRLLDLLQERKLLKNLKLLVLDEAH-RLLDMGFgpDLEEILRRLP--KKRQILLLSATLPRN 161
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
96-231 |
9.40e-06 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 47.01 E-value: 9.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 96 VIVAGETGSGKTT--QLPKICMELGRGVKGLIghTQPRrlaaRTVANRIAEELQTE--PGGCVGYKVRFSDhVSDNTMVK 171
Cdd:cd00046 4 VLITAPTGSGKTLaaLLAALLLLLKKGKKVLV--LVPT----KALALQTAERLRELfgPGIRVAVLVGGSS-AEEREKNK 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 172 LMTDGILLAEIQQDRLLMQ---------YDTIIIDEAHERSLNIDF-LLGYLRELLPKRPDLKVIITSAT 231
Cdd:cd00046 77 LGDADIIIATPDMLLNLLLredrlflkdLKLIIVDEAHALLIDSRGaLILDLAVRKAGLKNAQVILLSAT 146
|
|
| PRK01172 |
PRK01172 |
ATP-dependent DNA helicase; |
194-512 |
3.02e-04 |
|
ATP-dependent DNA helicase;
Pssm-ID: 100801 [Multi-domain] Cd Length: 674 Bit Score: 45.26 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 194 IIIDEAH-----ERSLNIDFLLGYLRELlpkRPDLKVIITSATIDPERFSRHFNNAPIIEVSGRTYPVEV----RYRPIV 264
Cdd:PRK01172 139 IVADEIHiigdeDRGPTLETVLSSARYV---NPDARILALSATVSNANELAQWLNASLIKSNFRPVPLKLgilyRKRLIL 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 265 EEADDTERDQLQAIFDAVEElgregPGDILIFMSGEREIRDTADGL---------MKLNLPHTEVLP------------- 322
Cdd:PRK01172 216 DGYERSQVDINSLIKETVND-----GGQVLVFVSSRKNAEDYAEMLiqhfpefndFKVSSENNNVYDdslnemlphgvaf 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 323 LYARLSNSEQNRVFQPHAGRRI--VLATNVAETSLTVPGiKYVIdpgTARISRYSyrtkvqRLPIEPVSQASANQRKGRC 400
Cdd:PRK01172 291 HHAGLSNEQRRFIEEMFRNRYIkvIVATPTLAAGVNLPA-RLVI---VRDITRYG------NGGIRYLSNMEIKQMIGRA 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 401 GRV---SEGICIrLYSED--------DFLS-RPEFTD-----PEILRTNLASVILQMTALGLGDIAAF---------PFV 454
Cdd:PRK01172 361 GRPgydQYGIGY-IYAASpasydaakKYLSgEPEPVIsymgsQRKVRFNTLAAISMGLASSMEDLILFynetlmaiqNGV 439
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1358765783 455 EAPDKRnIQDGVRLLEELGAITTDAQasvYKLTPLGRQLSQLPVDPRLARMVLEAQKH 512
Cdd:PRK01172 440 DEIDYY-IESSLKFLKENGFIKGDVT---LRATRLGKLTSDLYIDPESALILKSAFDH 493
|
|
| DEXHc_viral_Ns3 |
cd17931 |
DEXH-box helicase domain of NS3 protease-helicase; NS3 is a nonstructural multifunctional ... |
94-250 |
3.36e-04 |
|
DEXH-box helicase domain of NS3 protease-helicase; NS3 is a nonstructural multifunctional protein found in pestiviruses that contains an N-terminal protease and a C-terminal helicase. The N-terminal domain is a chymotrypsin-like serine protease, which is responsible for most of the maturation cleavages of the polyprotein precursor in the cytosolic side of the endoplasmic reticulum membrane. The C-terminal domain, about two-thirds of NS3, is a helicase belonging to superfamily 2 (SF2) thought to be important for unwinding highly structured regions of the RNA genome during replication. NS3 plays an essential role in viral polyprotein processing and genome replication. NS3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350689 [Multi-domain] Cd Length: 151 Bit Score: 42.54 E-value: 3.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 94 QVVIVAGETGSGKTTQ-LPKICMELGR-GVKGLIghtqprrLA-ARTVANRIAEELQTEPggcVGYK--VRFSDHvSDNT 168
Cdd:cd17931 2 QLTVLDLHPGAGKTTRvLPQIIREAIKkRLRTLV-------LApTRVVAAEMYEALRGLP---IRYRtgAVKEEH-GGNE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 169 MVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLRELLpKRPDLKVIITSATIDPERFSRHFNNAPIIE 248
Cdd:cd17931 71 IVDYMCHGTFTCRLLSPKRVPNYNLIIMDEAHFTDPASIAARGYIHTRV-EMGEAAVIFMTATPPGTVTPFPQSNHPIED 149
|
..
gi 1358765783 249 VS 250
Cdd:cd17931 150 FE 151
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
93-229 |
6.06e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.89 E-value: 6.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1358765783 93 HQVVIVAGETGSGKTTQLPKICMELGRGVKGLIghtqprRLAARTVANRIAEELQTEPGGcvgykvrfsdhvsdntMVKL 172
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGVI------YIDGEDILEEVLDQLLLIIVG----------------GKKA 59
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1358765783 173 MTDGILLAEIQQDRLL-MQYDTIIIDEAH------ERSLNIDFLLGYLRELLPKRPDLKVIITS 229
Cdd:smart00382 60 SGSGELRLRLALALARkLKPDVLILDEITslldaeQEALLLLLEELRLLLLLKSEKNLTVILTT 123
|
|
| FlhF |
TIGR03499 |
flagellar biosynthetic protein FlhF; [Cellular processes, Chemotaxis and motility] |
48-113 |
8.23e-03 |
|
flagellar biosynthetic protein FlhF; [Cellular processes, Chemotaxis and motility]
Pssm-ID: 274609 [Multi-domain] Cd Length: 282 Bit Score: 39.63 E-value: 8.23e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1358765783 48 EQLSQEMSEAAGKVLLREAARPAITypENLPVSQKKQDILnavRDHQVVIVAGETGSGKTTQLPKI 113
Cdd:TIGR03499 154 RELLEKLPEDADAEDAWRWLREALE--GMLPVKPEEDPIL---EQGGVIALVGPTGVGKTTTLAKL 214
|
|
| |
