|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11705 |
PRK11705 |
cyclopropane fatty acyl phospholipid synthase; |
5-372 |
0e+00 |
|
cyclopropane fatty acyl phospholipid synthase;
Pssm-ID: 183282 Cd Length: 383 Bit Score: 624.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 5 QIFQNILDFADVKINGDRPWDIQIHNEAVFDRVLKDGSLGFGESYMDGLWDCDAIDEMISRVLHAGIEDKLATTTKiqLG 84
Cdd:PRK11705 18 RIANELLARAGITINGSRPWDIQVHNPRFFKRVLQEGSLGLGESYMDGWWDCDRLDEFFSRVLRAGLDEKLPHHLK--DT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 85 LKAGASKLKHLFNPQSVERVTKDvpfHYDLGNDLFEAMLDPRMTYTCAYWKDSDDLKSAQEAKLDLVCRKMGLQPGMRLL 164
Cdd:PRK11705 96 LRILRARLFNLQSKKRAWIVGKE---HYDLGNDLFEAMLDPRMQYSCGYWKDADTLEEAQEAKLDLICRKLQLKPGMRVL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 165 DIGCGWGSFMMFAAEKYGVICDGLTLSKEQAALGQARAdeKGLPVNFILQDYRLYHpeQPYDRVVSIGMMEHVGPENYED 244
Cdd:PRK11705 173 DIGCGWGGLARYAAEHYGVSVVGVTISAEQQKLAQERC--AGLPVEIRLQDYRDLN--GQFDRIVSVGMFEHVGPKNYRT 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 245 YFKAAYSFLADDGIFLLHTIGSPKSKSATDPWIDKYIFPNGVIPSMAQIGASAEDYFNIEDVQNIGPDYDKTLVAWNENF 324
Cdd:PRK11705 249 YFEVVRRCLKPDGLFLLHTIGSNKTDTNVDPWINKYIFPNGCLPSVRQIAQASEGLFVMEDWHNFGADYDRTLMAWHENF 328
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1374243879 325 EAAWPQLADKYGERFYRMWRYYLLSCAGAFRCRDLNVWQFGLTKKGAE 372
Cdd:PRK11705 329 EAAWPELADNYSERFYRMWRYYLLSCAGAFRARDIQLWQVVFSPRGVE 376
|
|
| CMAS |
pfam02353 |
Mycolic acid cyclopropane synthetase; This family consist of ... |
106-364 |
2.75e-118 |
|
Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Pssm-ID: 396777 [Multi-domain] Cd Length: 272 Bit Score: 343.93 E-value: 2.75e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 106 KDVPFHYDLGNDLFEAMLDPRMTYTCAYWKDSDD-LKSAQEAKLDLVCRKMGLQPGMRLLDIGCGWGSFMMFAAEKYGVI 184
Cdd:pfam02353 7 ENIQAHYDLSNDFFALFLDPTMTYSCAYFERPDMtLEEAQQAKLDLILDKLGLKPGMTLLDIGCGWGGLMRRAAERYDVN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 185 CDGLTLSKEQAALGQARADEKGLP--VNFILQDYRLYhpEQPYDRVVSIGMMEHVGPENYEDYFKAAYSFLADDGIFLLH 262
Cdd:pfam02353 87 VVGLTLSKNQYKLARKRVAAEGLArkVEVLLQDYRDF--DEPFDRIVSVGMFEHVGHENYDTFFKKLYNLLPPGGLMLLH 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 263 TIGSPKSKSA-----TDPWIDKYIFPNGVIPSMAQIGASAEDY-FNIEDVQNIGPDYDKTLVAWNENFEAAWPQLADKYG 336
Cdd:pfam02353 165 TITGLHPDETserglPLKFIDKYIFPGGELPSISMIVESSSEAgFTVEDVESLRPHYAKTLDLWAENLQANKDEAIALQS 244
|
250 260
....*....|....*....|....*...
gi 1374243879 337 ERFYRMWRYYLLSCAGAFRCRDLNVWQF 364
Cdd:pfam02353 245 EEFYRMWMLYLTGCAVAFRIGYIDVHQF 272
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
110-263 |
1.55e-76 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 233.28 E-value: 1.55e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 110 FHYDLGNDLFEAMLDPRMTYTCAYWKDSDD-LKSAQEAKLDLVCRKMGLQPGMRLLDIGCGWGSFMMFAAEKYGVICDGL 188
Cdd:COG2230 1 HHYDLGNDFYRLFLDPTMTYSCAYFEDPDDtLEEAQEAKLDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVTGV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1374243879 189 TLSKEQAALGQARADEKGLP--VNFILQDYRLYHPEQPYDRVVSIGMMEHVGPENYEDYFKAAYSFLADDGIFLLHT 263
Cdd:COG2230 81 TLSPEQLEYARERAAEAGLAdrVEVRLADYRDLPADGQFDAIVSIGMFEHVGPENYPAYFAKVARLLKPGGRLLLHT 157
|
|
| mycolic_MTase |
NF040660 |
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include ... |
107-368 |
1.83e-70 |
|
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include tailoring enzymes that make site-specific modifications to mycolic acid precursor molecules. These include Mycobacterium tuberculosis enzymes MmaA1-MmaA4, CmaA1-CmaA2, and PcaA. The family also includes UmaA, reported to be the lone member of this family not involved in mycolic acid biosynthesis. No members of this family are found in species that lack mycolic acids. This model excludes two more distantly related paralogs, Rv0447c (UfaA1 ) and Rv3720, that are also encoded in the Mycobacterium tuberculosis H37Rv genome.
Pssm-ID: 468626 Cd Length: 283 Bit Score: 222.34 E-value: 1.83e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 107 DVPFHYDLGNDLFEAMLDPRMTYTCAYWKDSD-DLKSAQEAKLDLVCRKMGLQPGMRLLDIGCGWGSFMMFAAEKYGVIC 185
Cdd:NF040660 7 DVQAHYDLSDDFFALFLDPTQTYSCAYFERDDmTLEEAQIAKIDLALGKLNLEPGMTLLDIGCGWGATMRRAVEKYDVNV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 186 DGLTLSKEQAALGQARADEKGLPVN--FILQDYRLYhpEQPYDRVVSIGMMEHVGPENYEDYFKAAYSFLADDGIFLLHT 263
Cdd:NF040660 87 VGLTLSKNQAAHVQQVLDEIDTPRSrrVLLQGWEEF--DEPVDRIVSIGAFEHFGHERYDDFFKRAYNILPADGRMLLHT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 264 IGSPKSKSATD-------------PWIDKYIFPNGVIPSMAQIGASAEDY-FNIEDVQNIGPDYDKTLVAWNENFEAAWP 329
Cdd:NF040660 165 ITGLHRKEMHErglpltmelarfiKFIVTEIFPGGRLPSIEMVVEHAEKAgFTVTRVQSLQPHYARTLDLWADALQAHKD 244
|
250 260 270
....*....|....*....|....*....|....*....
gi 1374243879 330 QLADKYGERFYRMWRYYLLSCAGAFRCRDLNVWQFGLTK 368
Cdd:NF040660 245 EAIAIQSEEVYERYMKYLTGCAKLFRDGYIDVNQFTLAK 283
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
162-262 |
1.70e-09 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 54.74 E-value: 1.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 162 RLLDIGCGWGSFMMFAAEKYGVICDGLTLSKEQAALGQARADEKGLP-VNFILQDYR--LYHPEQPYDRVVSIGMMEHVg 238
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAALLADnVEVLKGDAEelPPEADESFDVIISDPPLHHL- 79
|
90 100
....*....|....*....|....
gi 1374243879 239 PENYEDYFKAAYSFLADDGIFLLH 262
Cdd:cd02440 80 VEDLARFLEEARRLLKPGGVLVLT 103
|
|
| PKS_MT |
smart00828 |
Methyltransferase in polyketide synthase (PKS) enzymes; |
162-261 |
7.49e-05 |
|
Methyltransferase in polyketide synthase (PKS) enzymes;
Pssm-ID: 214839 [Multi-domain] Cd Length: 224 Bit Score: 43.56 E-value: 7.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 162 RLLDIGCGWGSFMMFAAEKYGVI-CDGLTLSKEQAALGQARADEKGLP--VNFILQDYRLYHPEQPYDRVVSIGMMEHVg 238
Cdd:smart00828 2 RVLDFGCGYGSDLIDLAERHPHLqLHGYTISPEQAEVGRERIRALGLQgrIRIFYRDSAKDPFPDTYDLVFGFEVIHHI- 80
|
90 100
....*....|....*....|...
gi 1374243879 239 pENYEDYFKAAYSFLADDGIFLL 261
Cdd:smart00828 81 -KDKMDLFSNISRHLKDGGHLVL 102
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11705 |
PRK11705 |
cyclopropane fatty acyl phospholipid synthase; |
5-372 |
0e+00 |
|
cyclopropane fatty acyl phospholipid synthase;
Pssm-ID: 183282 Cd Length: 383 Bit Score: 624.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 5 QIFQNILDFADVKINGDRPWDIQIHNEAVFDRVLKDGSLGFGESYMDGLWDCDAIDEMISRVLHAGIEDKLATTTKiqLG 84
Cdd:PRK11705 18 RIANELLARAGITINGSRPWDIQVHNPRFFKRVLQEGSLGLGESYMDGWWDCDRLDEFFSRVLRAGLDEKLPHHLK--DT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 85 LKAGASKLKHLFNPQSVERVTKDvpfHYDLGNDLFEAMLDPRMTYTCAYWKDSDDLKSAQEAKLDLVCRKMGLQPGMRLL 164
Cdd:PRK11705 96 LRILRARLFNLQSKKRAWIVGKE---HYDLGNDLFEAMLDPRMQYSCGYWKDADTLEEAQEAKLDLICRKLQLKPGMRVL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 165 DIGCGWGSFMMFAAEKYGVICDGLTLSKEQAALGQARAdeKGLPVNFILQDYRLYHpeQPYDRVVSIGMMEHVGPENYED 244
Cdd:PRK11705 173 DIGCGWGGLARYAAEHYGVSVVGVTISAEQQKLAQERC--AGLPVEIRLQDYRDLN--GQFDRIVSVGMFEHVGPKNYRT 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 245 YFKAAYSFLADDGIFLLHTIGSPKSKSATDPWIDKYIFPNGVIPSMAQIGASAEDYFNIEDVQNIGPDYDKTLVAWNENF 324
Cdd:PRK11705 249 YFEVVRRCLKPDGLFLLHTIGSNKTDTNVDPWINKYIFPNGCLPSVRQIAQASEGLFVMEDWHNFGADYDRTLMAWHENF 328
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1374243879 325 EAAWPQLADKYGERFYRMWRYYLLSCAGAFRCRDLNVWQFGLTKKGAE 372
Cdd:PRK11705 329 EAAWPELADNYSERFYRMWRYYLLSCAGAFRARDIQLWQVVFSPRGVE 376
|
|
| CMAS |
pfam02353 |
Mycolic acid cyclopropane synthetase; This family consist of ... |
106-364 |
2.75e-118 |
|
Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Pssm-ID: 396777 [Multi-domain] Cd Length: 272 Bit Score: 343.93 E-value: 2.75e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 106 KDVPFHYDLGNDLFEAMLDPRMTYTCAYWKDSDD-LKSAQEAKLDLVCRKMGLQPGMRLLDIGCGWGSFMMFAAEKYGVI 184
Cdd:pfam02353 7 ENIQAHYDLSNDFFALFLDPTMTYSCAYFERPDMtLEEAQQAKLDLILDKLGLKPGMTLLDIGCGWGGLMRRAAERYDVN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 185 CDGLTLSKEQAALGQARADEKGLP--VNFILQDYRLYhpEQPYDRVVSIGMMEHVGPENYEDYFKAAYSFLADDGIFLLH 262
Cdd:pfam02353 87 VVGLTLSKNQYKLARKRVAAEGLArkVEVLLQDYRDF--DEPFDRIVSVGMFEHVGHENYDTFFKKLYNLLPPGGLMLLH 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 263 TIGSPKSKSA-----TDPWIDKYIFPNGVIPSMAQIGASAEDY-FNIEDVQNIGPDYDKTLVAWNENFEAAWPQLADKYG 336
Cdd:pfam02353 165 TITGLHPDETserglPLKFIDKYIFPGGELPSISMIVESSSEAgFTVEDVESLRPHYAKTLDLWAENLQANKDEAIALQS 244
|
250 260
....*....|....*....|....*...
gi 1374243879 337 ERFYRMWRYYLLSCAGAFRCRDLNVWQF 364
Cdd:pfam02353 245 EEFYRMWMLYLTGCAVAFRIGYIDVHQF 272
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
110-263 |
1.55e-76 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 233.28 E-value: 1.55e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 110 FHYDLGNDLFEAMLDPRMTYTCAYWKDSDD-LKSAQEAKLDLVCRKMGLQPGMRLLDIGCGWGSFMMFAAEKYGVICDGL 188
Cdd:COG2230 1 HHYDLGNDFYRLFLDPTMTYSCAYFEDPDDtLEEAQEAKLDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVTGV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1374243879 189 TLSKEQAALGQARADEKGLP--VNFILQDYRLYHPEQPYDRVVSIGMMEHVGPENYEDYFKAAYSFLADDGIFLLHT 263
Cdd:COG2230 81 TLSPEQLEYARERAAEAGLAdrVEVRLADYRDLPADGQFDAIVSIGMFEHVGPENYPAYFAKVARLLKPGGRLLLHT 157
|
|
| mycolic_MTase |
NF040660 |
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include ... |
107-368 |
1.83e-70 |
|
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include tailoring enzymes that make site-specific modifications to mycolic acid precursor molecules. These include Mycobacterium tuberculosis enzymes MmaA1-MmaA4, CmaA1-CmaA2, and PcaA. The family also includes UmaA, reported to be the lone member of this family not involved in mycolic acid biosynthesis. No members of this family are found in species that lack mycolic acids. This model excludes two more distantly related paralogs, Rv0447c (UfaA1 ) and Rv3720, that are also encoded in the Mycobacterium tuberculosis H37Rv genome.
Pssm-ID: 468626 Cd Length: 283 Bit Score: 222.34 E-value: 1.83e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 107 DVPFHYDLGNDLFEAMLDPRMTYTCAYWKDSD-DLKSAQEAKLDLVCRKMGLQPGMRLLDIGCGWGSFMMFAAEKYGVIC 185
Cdd:NF040660 7 DVQAHYDLSDDFFALFLDPTQTYSCAYFERDDmTLEEAQIAKIDLALGKLNLEPGMTLLDIGCGWGATMRRAVEKYDVNV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 186 DGLTLSKEQAALGQARADEKGLPVN--FILQDYRLYhpEQPYDRVVSIGMMEHVGPENYEDYFKAAYSFLADDGIFLLHT 263
Cdd:NF040660 87 VGLTLSKNQAAHVQQVLDEIDTPRSrrVLLQGWEEF--DEPVDRIVSIGAFEHFGHERYDDFFKRAYNILPADGRMLLHT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 264 IGSPKSKSATD-------------PWIDKYIFPNGVIPSMAQIGASAEDY-FNIEDVQNIGPDYDKTLVAWNENFEAAWP 329
Cdd:NF040660 165 ITGLHRKEMHErglpltmelarfiKFIVTEIFPGGRLPSIEMVVEHAEKAgFTVTRVQSLQPHYARTLDLWADALQAHKD 244
|
250 260 270
....*....|....*....|....*....|....*....
gi 1374243879 330 QLADKYGERFYRMWRYYLLSCAGAFRCRDLNVWQFGLTK 368
Cdd:NF040660 245 EAIAIQSEEVYERYMKYLTGCAKLFRDGYIDVNQFTLAK 283
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
164-257 |
1.60e-19 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 82.61 E-value: 1.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 164 LDIGCGWGSFMMFAAEKYGVICDGLTLSKEQAALGQARADEKGLPVNFILQDYR-LYHPEQPYDRVVSIGMMEHVGPENY 242
Cdd:pfam13649 2 LDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAEAGLNVEFVQGDAEdLPFPDGSFDLVVSSGVLHHLPDPDL 81
|
90
....*....|....*
gi 1374243879 243 EDYFKAAYSFLADDG 257
Cdd:pfam13649 82 EAALREIARVLKPGG 96
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
143-261 |
6.92e-17 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 78.42 E-value: 6.92e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 143 AQEAKLDLVCRKMGLQPGMRLLDIGCGWGSFMMFAAEKYGVICDGLTLSKEQAALGQARADEKGLP-VNFILQDYRLYH- 220
Cdd:COG0500 10 LLPGLAALLALLERLPKGGRVLDLGCGTGRNLLALAARFGGRVIGIDLSPEAIALARARAAKAGLGnVEFLVADLAELDp 89
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1374243879 221 -PEQPYDRVVSIGMMEHVGPENYEDYFKAAYSFLADDGIFLL 261
Cdd:COG0500 90 lPAESFDLVVAFGVLHHLPPEEREALLRELARALKPGGVLLL 131
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
157-264 |
1.25e-15 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 72.74 E-value: 1.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 157 LQPGMRLLDIGCGWGSFMMFAAEKyGVICDGLTLSKEQAALGQARADEkgLPVNFILQDYR-LYHPEQPYDRVVSIGMME 235
Cdd:COG2227 22 LPAGGRVLDVGCGTGRLALALARR-GADVTGVDISPEALEIARERAAE--LNVDFVQGDLEdLPLEDGSFDLVICSEVLE 98
|
90 100
....*....|....*....|....*....
gi 1374243879 236 HVgpENYEDYFKAAYSFLADDGIFLLHTI 264
Cdd:COG2227 99 HL--PDPAALLRELARLLKPGGLLLLSTP 125
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
149-267 |
3.53e-15 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 71.95 E-value: 3.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 149 DLVCRKMGLQPGMRLLDIGCGWGSFMMFAAEKyGVICDGLTLSKEQAALGQARADEKGLPVNFILQD-YRLYHPEQPYDR 227
Cdd:COG2226 12 EALLAALGLRPGARVLDLGCGTGRLALALAER-GARVTGVDISPEMLELARERAAEAGLNVEFVVGDaEDLPFPDGSFDL 90
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1374243879 228 VVSIGMMEHVgpENYEDYFKAAYSFLADDGIFLLHTIGSP 267
Cdd:COG2226 91 VISSFVLHHL--PDPERALAEIARVLKPGGRLVVVDFSPP 128
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
159-261 |
4.63e-10 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 55.99 E-value: 4.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 159 PGMRLLDIGCGWGSFMMFAAEKY-GVICDGLTLSKEQAALGQARADEkglpVNFILQDYRLYHPEQPYDRVVSIGMMEHV 237
Cdd:COG4106 1 PPRRVLDLGCGTGRLTALLAERFpGARVTGVDLSPEMLARARARLPN----VRFVVADLRDLDPPEPFDLVVSNAALHWL 76
|
90 100
....*....|....*....|....
gi 1374243879 238 gpENYEDYFKAAYSFLADDGIFLL 261
Cdd:COG4106 77 --PDHAALLARLAAALAPGGVLAV 98
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
143-261 |
1.49e-09 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 56.93 E-value: 1.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 143 AQEAKLDLVCRKMGLQPGMRLLDIGCGWGsfmMFAAE--KYGVICDGLTLSkeQAALgqARADEKGLPVNFILQDYR-LY 219
Cdd:COG4976 30 APALLAEELLARLPPGPFGRVLDLGCGTG---LLGEAlrPRGYRLTGVDLS--EEML--AKAREKGVYDRLLVADLAdLA 102
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1374243879 220 HPEQPYDRVVSIGMMEHVGpeNYEDYFKAAYSFLADDGIFLL 261
Cdd:COG4976 103 EPDGRFDLIVAADVLTYLG--DLAAVFAGVARALKPGGLFIF 142
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
162-262 |
1.70e-09 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 54.74 E-value: 1.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 162 RLLDIGCGWGSFMMFAAEKYGVICDGLTLSKEQAALGQARADEKGLP-VNFILQDYR--LYHPEQPYDRVVSIGMMEHVg 238
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAALLADnVEVLKGDAEelPPEADESFDVIISDPPLHHL- 79
|
90 100
....*....|....*....|....
gi 1374243879 239 PENYEDYFKAAYSFLADDGIFLLH 262
Cdd:cd02440 80 VEDLARFLEEARRLLKPGGVLVLT 103
|
|
| Methyltransf_23 |
pfam13489 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
159-267 |
1.02e-07 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 404385 [Multi-domain] Cd Length: 162 Bit Score: 51.27 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 159 PGMRLLDIGCGWGSFMMFAAEK----YGVicdgltlskEQAALGQARADEKGLPVNFILQDyrLYHPEQPYDRVVSIGMM 234
Cdd:pfam13489 22 SPGRVLDFGCGTGIFLRLLRAQgfsvTGV---------DPSPIAIERALLNVRFDQFDEQE--AAVPAGKFDVIVAREVL 90
|
90 100 110
....*....|....*....|....*....|...
gi 1374243879 235 EHVgpENYEDYFKAAYSFLADDGIFLLHTIGSP 267
Cdd:pfam13489 91 EHV--PDPPALLRQIAALLKPGGLLLLSTPLAS 121
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
164-261 |
3.58e-07 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 47.66 E-value: 3.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 164 LDIGCGWGSFMMFAAeKYGVICDGLTLSKEQAALgqARADEKGLPVNFILQD-YRLYHPEQPYDRVVSIGMMEHVgpENY 242
Cdd:pfam08241 1 LDVGCGTGLLTELLA-RLGARVTGVDISPEMLEL--AREKAPREGLTFVVGDaEDLPFPDNSFDLVLSSEVLHHV--EDP 75
|
90
....*....|....*....
gi 1374243879 243 EDYFKAAYSFLADDGIFLL 261
Cdd:pfam08241 76 ERALREIARVLKPGGILII 94
|
|
| PLN02244 |
PLN02244 |
tocopherol O-methyltransferase |
162-237 |
5.85e-06 |
|
tocopherol O-methyltransferase
Pssm-ID: 215135 [Multi-domain] Cd Length: 340 Bit Score: 47.82 E-value: 5.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 162 RLLDIGCGWGSFMMFAAEKYGVICDGLTLSKEQAALGQARADEKGL--PVNFILQDYRlyhpEQP-----YDRVVSIGMM 234
Cdd:PLN02244 121 RIVDVGCGIGGSSRYLARKYGANVKGITLSPVQAARANALAAAQGLsdKVSFQVADAL----NQPfedgqFDLVWSMESG 196
|
...
gi 1374243879 235 EHV 237
Cdd:PLN02244 197 EHM 199
|
|
| Methyltransf_12 |
pfam08242 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
164-259 |
1.08e-05 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 400515 [Multi-domain] Cd Length: 98 Bit Score: 43.90 E-value: 1.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 164 LDIGCGWGSFMMFAAEKY-GVICDGLTLSKEQAALGQARADEKGLPVNFILQDYRL---YHPEQPYDRVVSIGMMEHVgp 239
Cdd:pfam08242 1 LEIGCGTGTLLRALLEALpGLEYTGLDISPAALEAARERLAALGLLNAVRVELFQLdlgELDPGSFDVVVASNVLHHL-- 78
|
90 100
....*....|....*....|
gi 1374243879 240 ENYEDYFKAAYSFLADDGIF 259
Cdd:pfam08242 79 ADPRAVLRNIRRLLKPGGVL 98
|
|
| PTZ00098 |
PTZ00098 |
phosphoethanolamine N-methyltransferase; Provisional |
157-261 |
6.24e-05 |
|
phosphoethanolamine N-methyltransferase; Provisional
Pssm-ID: 173391 [Multi-domain] Cd Length: 263 Bit Score: 44.19 E-value: 6.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 157 LQPGMRLLDIGCGWGSFMMFAAEKYGVICDGLTLSKEQAALGQARADEKGlPVNFILQD-YRLYHPEQPYDRVVSIGMME 235
Cdd:PTZ00098 50 LNENSKVLDIGSGLGGGCKYINEKYGAHVHGVDICEKMVNIAKLRNSDKN-KIEFEANDiLKKDFPENTFDMIYSRDAIL 128
|
90 100
....*....|....*....|....*.
gi 1374243879 236 HVGPENYEDYFKAAYSFLADDGIFLL 261
Cdd:PTZ00098 129 HLSYADKKKLFEKCYKWLKPNGILLI 154
|
|
| PKS_MT |
smart00828 |
Methyltransferase in polyketide synthase (PKS) enzymes; |
162-261 |
7.49e-05 |
|
Methyltransferase in polyketide synthase (PKS) enzymes;
Pssm-ID: 214839 [Multi-domain] Cd Length: 224 Bit Score: 43.56 E-value: 7.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 162 RLLDIGCGWGSFMMFAAEKYGVI-CDGLTLSKEQAALGQARADEKGLP--VNFILQDYRLYHPEQPYDRVVSIGMMEHVg 238
Cdd:smart00828 2 RVLDFGCGYGSDLIDLAERHPHLqLHGYTISPEQAEVGRERIRALGLQgrIRIFYRDSAKDPFPDTYDLVFGFEVIHHI- 80
|
90 100
....*....|....*....|...
gi 1374243879 239 pENYEDYFKAAYSFLADDGIFLL 261
Cdd:smart00828 81 -KDKMDLFSNISRHLKDGGHLVL 102
|
|
| ubiE |
PRK00216 |
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ... |
111-215 |
7.87e-05 |
|
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;
Pssm-ID: 234689 [Multi-domain] Cd Length: 239 Bit Score: 43.60 E-value: 7.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 111 HYDLGNDLFEAMLDpRmtytcaYWKDSddlksaqeakldlVCRKMGLQPGMRLLDIGCGWGSFMMFAAEKYGVI--CDGL 188
Cdd:PRK00216 23 KYDLMNDLLSFGLH-R------VWRRK-------------TIKWLGVRPGDKVLDLACGTGDLAIALAKAVGKTgeVVGL 82
|
90 100
....*....|....*....|....*....
gi 1374243879 189 TLSKEQAALGQARADEKGL--PVNFILQD 215
Cdd:PRK00216 83 DFSEGMLAVGREKLRDLGLsgNVEFVQGD 111
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
153-237 |
3.13e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 41.85 E-value: 3.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 153 RKMGLQPGMRLLDIGCGWGSFMMFAAEKYG----VIcdGLTLSKEQAALGQARADEKGLPVNFILQD-YRLYHPEQPYDR 227
Cdd:PRK08317 13 ELLAVQPGDRVLDVGCGPGNDARELARRVGpegrVV--GIDRSEAMLALAKERAAGLGPNVEFVRGDaDGLPFPDGSFDA 90
|
90
....*....|
gi 1374243879 228 VVSIGMMEHV 237
Cdd:PRK08317 91 VRSDRVLQHL 100
|
|
| PRK14103 |
PRK14103 |
trans-aconitate 2-methyltransferase; Provisional |
149-230 |
1.31e-03 |
|
trans-aconitate 2-methyltransferase; Provisional
Pssm-ID: 184509 Cd Length: 255 Bit Score: 40.06 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 149 DLVCRkMGLQPGMRLLDIGCGWGSFMMFAAEKY-GVICDGLTLSKEQAAlgqaRADEKGlpVNFILQDYRLYHPEQPYDR 227
Cdd:PRK14103 20 DLLAR-VGAERARRVVDLGCGPGNLTRYLARRWpGAVIEALDSSPEMVA----AARERG--VDARTGDVRDWKPKPDTDV 92
|
...
gi 1374243879 228 VVS 230
Cdd:PRK14103 93 VVS 95
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
159-261 |
1.92e-03 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 38.55 E-value: 1.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 159 PGMRLLDIGCGWGSFMMFAAEKYGVICD--GLTLSKEQAALGQARADEKGLP-VNFILQDY----RLYHpEQPYDRVVSI 231
Cdd:pfam13847 3 KGMRVLDLGCGTGHLSFELAEELGPNAEvvGIDISEEAIEKARENAQKLGFDnVEFEQGDIeelpELLE-DDKFDVVISN 81
|
90 100 110
....*....|....*....|....*....|
gi 1374243879 232 GMMEHVGpeNYEDYFKAAYSFLADDGIFLL 261
Cdd:pfam13847 82 CVLNHIP--DPDKVLQEILRVLKPGGRLII 109
|
|
| PLN02336 |
PLN02336 |
phosphoethanolamine N-methyltransferase |
154-247 |
2.32e-03 |
|
phosphoethanolamine N-methyltransferase
Pssm-ID: 177970 [Multi-domain] Cd Length: 475 Bit Score: 39.73 E-value: 2.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 154 KMGLQPGMRLLDIGCGWGSFMMFAAEKYGVICDGLTLSKEQAALGQARADEKGLPVNFILQD-YRLYHPEQPYDRVVSIG 232
Cdd:PLN02336 261 KLDLKPGQKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALERAIGRKCSVEFEVADcTKKTYPDNSFDVIYSRD 340
|
90
....*....|....*..
gi 1374243879 233 MMEHV--GPENYEDYFK 247
Cdd:PLN02336 341 TILHIqdKPALFRSFFK 357
|
|
| MetW |
pfam07021 |
Methionine biosynthesis protein MetW; This family consists of several bacterial and one ... |
157-229 |
3.22e-03 |
|
Methionine biosynthesis protein MetW; This family consists of several bacterial and one archaeal methionine biosynthesis MetW proteins. Biosynthesis of methionine from homoserine in Pseudomonas putida takes place in three steps. The first step is the acylation of homoserine to yield an acyl-L-homoserine. This reaction is catalyzed by the products of the metXW genes and is equivalent to the first step in enterobacteria, gram-positive bacteria and fungi, except that in these microorganizms the reaction is catalyzed by a single polypeptide (the product of the metA gene in Escherichia coli and the met5 gene product in Neurospora crassa). In Pseudomonas putida, as in gram-positive bacteria and certain fungi, the second and third steps are a direct sulfhydrylation that converts the O-acyl-L-homoserine into homocysteine and further methylation to yield methionine. The latter reaction can be mediated by either of the two methionine synthetases present in the cells.
Pssm-ID: 399779 Cd Length: 193 Bit Score: 38.21 E-value: 3.22e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1374243879 157 LQPGMRLLDIGCGWGSFMMFAAEKYGVICDGLTLSKEqaalGQARADEKGLPVnfILQDYRL---YHPEQPYDRVV 229
Cdd:pfam07021 11 IPPGSRVLDLGCGDGTLLYLLKEEKGVDGYGIELDAA----GVAECVAKGLYV--IQGDLDEgleHFPDKSFDYVI 80
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
157-259 |
3.83e-03 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 38.59 E-value: 3.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 157 LQPGMRLLDIGCGWG--SFMMfAAEKYGVICDGLTLSKEQAALGQARADEKGLP--VNFI---LQDYRLYHPEQPYDRVV 229
Cdd:COG4123 35 VKKGGRVLDLGTGTGviALML-AQRSPGARITGVEIQPEAAELARRNVALNGLEdrITVIhgdLKEFAAELPPGSFDLVV 113
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1374243879 230 S-------------------IGMMEHVGPenYEDYFKAAYSFLADDGIF 259
Cdd:COG4123 114 SnppyfkagsgrkspdearaIARHEDALT--LEDLIRAAARLLKPGGRF 160
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
158-261 |
9.86e-03 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 36.71 E-value: 9.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1374243879 158 QPGMRLLDIGCGWGSFMMFAAEKYGVIcdGLTLS-KEQAALGQAR--ADEKGLP-VNFILQDYRLYHPEQPYDRVVS--- 230
Cdd:COG2813 48 PLGGRVLDLGCGYGVIGLALAKRNPEA--RVTLVdVNARAVELARanAAANGLEnVEVLWSDGLSGVPDGSFDLILSnpp 125
|
90 100 110
....*....|....*....|....*....|...
gi 1374243879 231 --IGMmeHVGPENYEDYFKAAYSFLADDGIFLL 261
Cdd:COG2813 126 fhAGR--AVDKEVAHALIADAARHLRPGGELWL 156
|
|
| |
