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IlvD/Edd family dehydratase [Agrobacterium pusense]
Protein Classification
IlvD/Edd family dehydratase ( domain architecture ID 10014112 )
IlvD/Edd family dehydratase similar to Caulobacter vibrioides D-xylonate dehydratase that catalyzes the dehydration of D-xylonate in the non-phosphorylative oxidation pathway of this pentose sugar
List of domain hits
Name
Accession
Description
Interval
E-value
PRK13017
PRK13017 dihydroxy-acid dehydratase; Provisional
1-594
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237272
Cd Length: 596
Bit Score: 1191.69
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 1 M SDE K T P M RRLRSQ D WFDNPDH L DMTALYLER F MNYG V T P EEL R SGKP V IGIAQ S GSDL T PCNR V H V EL VK RV RD GIRDA 80
Cdd:PRK13017 1 M MMP K K P P RRLRSQ E WFDNPDH P DMTALYLER Y MNYG L T R EEL Q SGKP I IGIAQ T GSDL S PCNR H H L EL AE RV KE GIRDA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 81 GGIP I EFP T HP MF E NC KRPTAALDRNLAYL S LVE V LYGYPLDGVVLTTGCDKTTP SA LMAA S TVD I PAIVLSGGPMLDG Y 160
Cdd:PRK13017 81 GGIP M EFP V HP IQ E TG KRPTAALDRNLAYL G LVE I LYGYPLDGVVLTTGCDKTTP AC LMAA A TVD L PAIVLSGGPMLDG W 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 161 HEG DL VGSGTVIW RM R RKYG AGEI TR EEF LQAALE SAPSVGHCNTMGTASTMNA I AEALGMSL T GC G AIPA A YRERGQMA 240
Cdd:PRK13017 161 HEG ER VGSGTVIW KA R ELLA AGEI DY EEF MELVAS SAPSVGHCNTMGTASTMNA L AEALGMSL P GC A AIPA P YRERGQMA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 241 Y R TG R R A VE L V V E NI KPSDI M TREAF L NAI R VNSAIGGSTNA QP HL A A M A K HAGVEL REE DWQ VH G Y D I PLL A N I QPAGK 320
Cdd:PRK13017 241 Y A TG K R I VE M V W E DL KPSDI L TREAF E NAI V VNSAIGGSTNA PI HL I A I A R HAGVEL SLD DWQ RV G E D V PLL V N L QPAGK 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 321 W LGE KY HRAGG T PA IMW ELL Q AG K L D G SCR TV T GRT VA EN LE G REST DRDVI L PYD K PLKERAGFLVL K GNLFD F AIMKT 400
Cdd:PRK13017 321 Y LGE DF HRAGG V PA VLA ELL R AG L L H G DAL TV S GRT IG EN IA G APAP DRDVI R PYD A PLKERAGFLVL R GNLFD S AIMKT 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 401 SVIS A EFR Q RYL N EPG H E GI FEGR C VVFDG S EDYHARI N DP S LDIDE RT ILVIRGAGP L G W PGSAEVVNMQPP D ALLK K G 480
Cdd:PRK13017 401 SVIS E EFR E RYL S EPG D E NA FEGR A VVFDG P EDYHARI D DP A LDIDE HC ILVIRGAGP V G Y PGSAEVVNMQPP A ALLK R G 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 481 I T SLP T IGDGRQSGT AD SPSILNASPE S A A GGGLA W LRTGD V IRID F NK GECN VLV P DEELA A R K A DGI P A VP ADA TPWQ 560
Cdd:PRK13017 481 I R SLP C IGDGRQSGT SG SPSILNASPE A A V GGGLA L LRTGD R IRID L NK RRVD VLV S DEELA R R R A ALK P P VP PSQ TPWQ 560
570 580 590
....*....|....*....|....*....|....*.
gi 1376268663 561 RI YR QS V T QLS D GA V LE G A ADFR R I A EKM -- PRHNH 594
Cdd:PRK13017 561 EL YR KH V G QLS T GA C LE P A TLYQ R V A ATR gv PRHNH 596
Name
Accession
Description
Interval
E-value
PRK13017
PRK13017 dihydroxy-acid dehydratase; Provisional
1-594
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237272
Cd Length: 596
Bit Score: 1191.69
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 1 M SDE K T P M RRLRSQ D WFDNPDH L DMTALYLER F MNYG V T P EEL R SGKP V IGIAQ S GSDL T PCNR V H V EL VK RV RD GIRDA 80
Cdd:PRK13017 1 M MMP K K P P RRLRSQ E WFDNPDH P DMTALYLER Y MNYG L T R EEL Q SGKP I IGIAQ T GSDL S PCNR H H L EL AE RV KE GIRDA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 81 GGIP I EFP T HP MF E NC KRPTAALDRNLAYL S LVE V LYGYPLDGVVLTTGCDKTTP SA LMAA S TVD I PAIVLSGGPMLDG Y 160
Cdd:PRK13017 81 GGIP M EFP V HP IQ E TG KRPTAALDRNLAYL G LVE I LYGYPLDGVVLTTGCDKTTP AC LMAA A TVD L PAIVLSGGPMLDG W 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 161 HEG DL VGSGTVIW RM R RKYG AGEI TR EEF LQAALE SAPSVGHCNTMGTASTMNA I AEALGMSL T GC G AIPA A YRERGQMA 240
Cdd:PRK13017 161 HEG ER VGSGTVIW KA R ELLA AGEI DY EEF MELVAS SAPSVGHCNTMGTASTMNA L AEALGMSL P GC A AIPA P YRERGQMA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 241 Y R TG R R A VE L V V E NI KPSDI M TREAF L NAI R VNSAIGGSTNA QP HL A A M A K HAGVEL REE DWQ VH G Y D I PLL A N I QPAGK 320
Cdd:PRK13017 241 Y A TG K R I VE M V W E DL KPSDI L TREAF E NAI V VNSAIGGSTNA PI HL I A I A R HAGVEL SLD DWQ RV G E D V PLL V N L QPAGK 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 321 W LGE KY HRAGG T PA IMW ELL Q AG K L D G SCR TV T GRT VA EN LE G REST DRDVI L PYD K PLKERAGFLVL K GNLFD F AIMKT 400
Cdd:PRK13017 321 Y LGE DF HRAGG V PA VLA ELL R AG L L H G DAL TV S GRT IG EN IA G APAP DRDVI R PYD A PLKERAGFLVL R GNLFD S AIMKT 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 401 SVIS A EFR Q RYL N EPG H E GI FEGR C VVFDG S EDYHARI N DP S LDIDE RT ILVIRGAGP L G W PGSAEVVNMQPP D ALLK K G 480
Cdd:PRK13017 401 SVIS E EFR E RYL S EPG D E NA FEGR A VVFDG P EDYHARI D DP A LDIDE HC ILVIRGAGP V G Y PGSAEVVNMQPP A ALLK R G 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 481 I T SLP T IGDGRQSGT AD SPSILNASPE S A A GGGLA W LRTGD V IRID F NK GECN VLV P DEELA A R K A DGI P A VP ADA TPWQ 560
Cdd:PRK13017 481 I R SLP C IGDGRQSGT SG SPSILNASPE A A V GGGLA L LRTGD R IRID L NK RRVD VLV S DEELA R R R A ALK P P VP PSQ TPWQ 560
570 580 590
....*....|....*....|....*....|....*.
gi 1376268663 561 RI YR QS V T QLS D GA V LE G A ADFR R I A EKM -- PRHNH 594
Cdd:PRK13017 561 EL YR KH V G QLS T GA C LE P A TLYQ R V A ATR gv PRHNH 596
ILVD_EDD
pfam00920 Dehydratase family;
47-574
0e+00
Dehydratase family;
Pssm-ID: 459998
Cd Length: 513
Bit Score: 670.58
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 47 KP V IGIA Q S G SDL T PC NRVHV EL VKR V RD G I R D AGG I P I EF P T HP ------ M FENCK R pt AA L D - R N L AYL S LV E V L YGY 119
Cdd:pfam00920 1 KP I IGIA N S Y SDL V PC HVHLR EL AEA V KE G V R E AGG V P A EF N T IG vcdgia M GHEGM R -- YS L P s R E L IAD S IE E M L RAH 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 120 P L DG V VL TT GCDK TT P SA LMAA STVD IPAI VL SGGPML D G yhegdlv GSGT VIWRMRRK Y G AG E I TR EE F L QAALESA P S 199
Cdd:pfam00920 79 P F DG L VL IG GCDK IV P GM LMAA ARLN IPAI FV SGGPML P G ------- GSGT DEFEAVGA Y A AG K I SE EE L L EIERAAC P G 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 200 V G H C NT MGTA S TM NAI AEALG M SL T G CGA IPA AYR ER GQM A YRT GRR A VELV V E N IKP S DI M TR E AF L NAI R V NS A I GGS 279
Cdd:pfam00920 152 C G S C GG MGTA N TM ACL AEALG L SL P G SAT IPA VSA ER LRL A REA GRR I VELV E E D IKP R DI L TR K AF E NAI V V DM A L GGS 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 280 TNA QP HL A A M A KH AGV E L REE D WQVHGYDI PLLA NIQ P A GK W L G E KY HRAGG T PA IMW ELL Q A g K L D G SCR TVTG R T VA E 359
Cdd:pfam00920 232 TNA VL HL L A I A RE AGV D L TLD D FDRISRKV PLLA DLK P S GK Y L M E DF HRAGG V PA VLK ELL D A - L L H G DVL TVTG K T LG E 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 360 NL EGR E ST D R DVI L P Y D K P LKERA G FL VLKGNL F - D F A IM KTS VISA E FRQ rylnepghegi FEG RCV VFD GS ED YH A R I 438
Cdd:pfam00920 311 NL ADA E VR D Q DVI R P L D N P ISPTG G LA VLKGNL A p D G A VV KTS AVDP E MLV ----------- FEG PAR VFD SE ED AL A A I 379
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 439 N D P sl D I DERTIL VIR GA GP L G W PG SA E V vn MQ P PD ALL KK G I - TSLPT I G DGR Q SG TADS PSI LNA SPE S A A GG GL A WL 517
Cdd:pfam00920 380 L D G -- K I KAGDVV VIR YE GP K G G PG MP E M -- LT P TS ALL GA G L g KDVAL I T DGR F SG ASRG PSI GHV SPE A A V GG PI A LV 455
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 1376268663 518 R T GD V IRID FNKGECNV LV P DEELAAR K A DGI P AV P - ADATPWQRI Y RQS V TQL S D GA 574
Cdd:pfam00920 456 R D GD I IRID IPNRTLDL LV S DEELAAR R A AWK P PE P k VKGRGYLAK Y AKL V SSA S E GA 513
IlvD
COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, ...
8-577
2.24e-158
Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; Dihydroxyacid dehydratase/phosphogluconate dehydratase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439899
Cd Length: 558
Bit Score: 464.87
E-value: 2.24e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 8 M RRL RS QDWFDNPDHLDMT AL Y le R FM ny G V T P E EL rs GKP V IGIA Q S GSDLT P CN r VH V - E L VKR V RD GIR D AGG I P I E 86
Cdd:COG0129 1 M PKM RS DTVTKGRERAPAR AL L -- R AT -- G L T D E DF -- GKP I IGIA N S WNEIV P GH - VH L d D L AEA V KE GIR A AGG V P F E 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 87 F P T hpmfenckrpt A A LDRNL A ------- Y l SL --------- V E - VLYGYPL DG V V LTT GCDK T TP SA LMAA STVD IP A I 149
Cdd:COG0129 74 F N T ----------- I A VSDGI A mghegmr Y - SL psreliads I E t MVNAHCF DG L V CIP GCDK I TP GM LMAA ARLN IP S I 141
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 150 VLS GGPML D G YHE G --------- DL VG sgtviwrmrr K Y G AG E I TR EE FLQAALESA P SV G H C NT M G TA S TM NAIA EALG 220
Cdd:COG0129 142 FVY GGPML P G KYD G kdldivdvf EA VG ---------- A Y A AG K I SD EE LKEIERNAC P GC G S C SG M F TA N TM ACLT EALG 211
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 221 M SL T G C G A IPA AYR ER GQM A YRT GRR A VELV VEN IKP S DI M TREAF L NAI R V NS A I GGSTN AQP HL A A M A KH AGV E L REE 300
Cdd:COG0129 212 L SL P G S G T IPA VSA ER RRL A REA GRR I VELV EKD IKP R DI L TREAF E NAI A V DM A L GGSTN TVL HL L A I A HE AGV D L TLD 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 301 D WQVHGYDI P L L ANIQ P A GK WLG E KY HRAGG T PA I M W ELL Q AG K L D G S C R TVTG R T V AENL EG - REST D R DVI L P Y D K P L 379
Cdd:COG0129 292 D FDRISRRT P H L CDLK P S GK YHM E DL HRAGG I PA V M K ELL D AG L L H G D C L TVTG K T L AENL AD a DIDR D Q DVI R P L D N P Y 371
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 380 KERA G FLV L K GNL F - D F A IM KT SVISAEFRQ rylnepghegi FEG RCV VFD GS E DYHAR I NDP sl D I DERTIL VIR GA GP 458
Cdd:COG0129 372 SPTG G LAI L R GNL A p D G A VV KT AGVDESMLV ----------- FEG PAR VFD SE E EAVEA I LGG -- K I KAGDVV VIR YE GP 438
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 459 L G W PG SA E vvn M QP P DAL LK - K G ------- IT slptig DGR Q SG TADSP SI LNA SPE S A A GG GL A WLRT GD V I R ID FNKG 530
Cdd:COG0129 439 K G G PG MR E --- M LS P TSA LK g M G lgksval IT ------ DGR F SG GTRGL SI GHV SPE A A E GG PI A LVED GD I I T ID IPAR 509
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 1376268663 531 ECNV LV P DEELA A R K A DGI P AV P ADATPWQRI Y RQS V TQL S D GAV LE 577
Cdd:COG0129 510 TLDL LV S DEELA R R R A AWK P PE P RVTSGVLAK Y AKL V SSA S K GAV TD 556
ilvD
TIGR00110 dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth ...
37-576
3.04e-123
dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth step in valine and isoleucine biosynthesis. It contains a catalytically essential [4Fe-4S] cluster This model generates scores of up to 150 bits vs. 6-phosphogluconate dehydratase, a homologous enzyme. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272910
Cd Length: 535
Bit Score: 374.06
E-value: 3.04e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 37 G V T P E EL rs GKP V IG I A Q S GSDLT P CN r V H V - E L VKR V RD GI RD AGG IPI EF P T HPMFENCKRPTAAL ----- D R NLAYL 110
Cdd:TIGR00110 3 G F T D E DF -- GKP F IG V A N S YTTIV P GH - M H L r D L AQA V KE GI EA AGG VAF EF N T IAVCDGIAMGHEGM kyslp S R EIIAD 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 111 S LVEVLYGYPL DG V V LTTG CDK T TP SA LMAA STVD IP A I VLS GGPML D G - YHE G DLVGSGTVIWRM r RK Y G AG E I TR EE F 189
Cdd:TIGR00110 80 S VETMVNAHRF DG L V CIPS CDK I TP GM LMAA ARLN IP S I FVT GGPML P G h TKL G KKIDLVSAFEAV - GE Y A AG K I SE EE L 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 190 LQAALESA P SV G H C NT M G TA S TM NAIA EALG M SL T GC GAIP A AYR E RGQM A YRT G R R A VELV VE NIKP S DI M T R EAF L NA 269
Cdd:TIGR00110 159 EEIERSAC P GC G S C SG M F TA N TM ACLT EALG L SL P GC STML A TSA E KKRI A KNS G K R I VELV KK NIKP R DI L T K EAF E NA 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 270 I R V NS A I GGSTN AQP HL A A M A KH AGV E L REE D WQVHGYDI P LL A NIQ P A GK WLG E KY HRAGG T PA IMW EL LQA G K L D G SC 349
Cdd:TIGR00110 239 I T V DM A L GGSTN TVL HL L A I A NE AGV D L SLD D FDRLSRKV P HI A SLA P S GK YVM E DL HRAGG I PA VLK EL DRE G L L H G DT 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 350 R TVTG R T VA E N LE GRES -- TDR DVI L P Y D K P LKERA G FLV LKGNL F - DF A IM K TSVIS aefrqrylnepgh E GI -- FEG R 424
Cdd:TIGR00110 319 L TVTG K T LG E I LE QAPV ip EGQ DVI R P L D N P VHQEG G LAI LKGNL A p NG A VV K IAGVD ------------- E DM tk FEG P 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 425 CV VF DGS E DYHAR I NDP sl D I D E RTIL VIR GA GP L G W PG SA E VVN mq P PD A LLKK G I - T S LPT I G DGR Q SG TADSPS I LN 503
Cdd:TIGR00110 386 AK VF ESE E EALEA I LGG -- K I K E GDVV VIR YE GP K G G PG MP E MLA -- P TS A IKGM G L g K S VAL I T DGR F SG GTRGLC I GH 461
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1376268663 504 A SPE S A A GG GL A WLRT GD V I R ID FNKGECNVL V P DEELA A R K A DGIPAV P ADATPWQRI Y RQS V TQLSD GAVL 576
Cdd:TIGR00110 462 V SPE A A E GG PI A LVED GD I I I ID IPNRKLDLQ V S DEELA E R R A SWKAPE P RYVKGYLAK Y AKL V SSADE GAVL 534
Name
Accession
Description
Interval
E-value
PRK13017
PRK13017 dihydroxy-acid dehydratase; Provisional
1-594
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237272
Cd Length: 596
Bit Score: 1191.69
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 1 M SDE K T P M RRLRSQ D WFDNPDH L DMTALYLER F MNYG V T P EEL R SGKP V IGIAQ S GSDL T PCNR V H V EL VK RV RD GIRDA 80
Cdd:PRK13017 1 M MMP K K P P RRLRSQ E WFDNPDH P DMTALYLER Y MNYG L T R EEL Q SGKP I IGIAQ T GSDL S PCNR H H L EL AE RV KE GIRDA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 81 GGIP I EFP T HP MF E NC KRPTAALDRNLAYL S LVE V LYGYPLDGVVLTTGCDKTTP SA LMAA S TVD I PAIVLSGGPMLDG Y 160
Cdd:PRK13017 81 GGIP M EFP V HP IQ E TG KRPTAALDRNLAYL G LVE I LYGYPLDGVVLTTGCDKTTP AC LMAA A TVD L PAIVLSGGPMLDG W 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 161 HEG DL VGSGTVIW RM R RKYG AGEI TR EEF LQAALE SAPSVGHCNTMGTASTMNA I AEALGMSL T GC G AIPA A YRERGQMA 240
Cdd:PRK13017 161 HEG ER VGSGTVIW KA R ELLA AGEI DY EEF MELVAS SAPSVGHCNTMGTASTMNA L AEALGMSL P GC A AIPA P YRERGQMA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 241 Y R TG R R A VE L V V E NI KPSDI M TREAF L NAI R VNSAIGGSTNA QP HL A A M A K HAGVEL REE DWQ VH G Y D I PLL A N I QPAGK 320
Cdd:PRK13017 241 Y A TG K R I VE M V W E DL KPSDI L TREAF E NAI V VNSAIGGSTNA PI HL I A I A R HAGVEL SLD DWQ RV G E D V PLL V N L QPAGK 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 321 W LGE KY HRAGG T PA IMW ELL Q AG K L D G SCR TV T GRT VA EN LE G REST DRDVI L PYD K PLKERAGFLVL K GNLFD F AIMKT 400
Cdd:PRK13017 321 Y LGE DF HRAGG V PA VLA ELL R AG L L H G DAL TV S GRT IG EN IA G APAP DRDVI R PYD A PLKERAGFLVL R GNLFD S AIMKT 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 401 SVIS A EFR Q RYL N EPG H E GI FEGR C VVFDG S EDYHARI N DP S LDIDE RT ILVIRGAGP L G W PGSAEVVNMQPP D ALLK K G 480
Cdd:PRK13017 401 SVIS E EFR E RYL S EPG D E NA FEGR A VVFDG P EDYHARI D DP A LDIDE HC ILVIRGAGP V G Y PGSAEVVNMQPP A ALLK R G 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 481 I T SLP T IGDGRQSGT AD SPSILNASPE S A A GGGLA W LRTGD V IRID F NK GECN VLV P DEELA A R K A DGI P A VP ADA TPWQ 560
Cdd:PRK13017 481 I R SLP C IGDGRQSGT SG SPSILNASPE A A V GGGLA L LRTGD R IRID L NK RRVD VLV S DEELA R R R A ALK P P VP PSQ TPWQ 560
570 580 590
....*....|....*....|....*....|....*.
gi 1376268663 561 RI YR QS V T QLS D GA V LE G A ADFR R I A EKM -- PRHNH 594
Cdd:PRK13017 561 EL YR KH V G QLS T GA C LE P A TLYQ R V A ATR gv PRHNH 596
PRK06131
PRK06131 dihydroxy-acid dehydratase; Validated
9-594
0e+00
dihydroxy-acid dehydratase; Validated
Pssm-ID: 235708
Cd Length: 571
Bit Score: 902.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 9 RR LRS QD WF DNP D hld MT A L Y LER FM NYGVT P E EL RS G K P V IGI AQSG SDL T PCN RVHVE L VK RV RD G IRD AGG I P I EFP 88
Cdd:PRK06131 3 GL LRS LA WF GDD D --- FR A F Y HRS FM KNQGY P D EL FD G R P I IGI CNTW SDL N PCN AHFRQ L AE RV KR G VLE AGG F P V EFP 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 89 THPMF E NCK RPTA A L D RNLA YLSLV E VLY GYP L DGVVL TT GCDKTTP SA LM A A ST VD I PAIVLSGGPML D G Y H E G DLV GS 168
Cdd:PRK06131 80 VISLG E SFL RPTA M L Y RNLA AMDVE E MIR GYP I DGVVL LG GCDKTTP AL LM G A AS VD L PAIVLSGGPML N G K H K G ERL GS 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 169 GT VI W RMRRKYG AGEI TR EEFL Q A ALES A P S V G H CNTMGTASTM NAI AEALGMSL T G CG AIPA AYRE R GQ MA YR TGRR A V 248
Cdd:PRK06131 160 GT DV W KYWEELR AGEI DL EEFL E A EAGM A R S A G T CNTMGTASTM ACM AEALGMSL P G NA AIPA VDAR R IR MA EL TGRR I V 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 249 E L V V E NI KPSDI M TREAF L NAIRVN S AIGGSTNA QP HL A A M A KH AGVEL REE DW QVH G Y D I P L L A N I QP A G KW L G E KYHR 328
Cdd:PRK06131 240 E M V H E DL KPSDI L TREAF E NAIRVN A AIGGSTNA VI HL I A I A GR AGVEL DLD DW DRI G R D V P V L V N L QP S G EY L M E DFYY 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 329 AGG T PA IMW EL LQ ag K L DGSCR TV T G R T VA ENL E G RESTDR DVI L P Y D K PLK ERA G FL VL K GNL F - D F A IM K T S VI S A E F 407
Cdd:PRK06131 320 AGG L PA VLR EL GE -- L L HLDAL TV N G K T LG ENL A G APVYND DVI R P L D N PLK PEG G IA VL R GNL A p D G A VI K P S AA S P E L 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 408 RQR ylnepghegif EGR C VVF D G S EDY H ARI N DP S LD I DE R T I LV I R G AGP L G W PG SA EV V NM QP P DA LL KK G ITSLPT I 487
Cdd:PRK06131 398 LKH ----------- EGR A VVF E G Y EDY K ARI D DP D LD V DE D T V LV L R N AGP K G Y PG MP EV G NM PI P KK LL RQ G VKDMVR I 466
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 488 G D G R Q SGTA DSPSI L NAS PE S AAGG G LA WL RTGD V IR I D FNKGECNV LV P DEELA A R K A DGI P AV P ADATPW Q RI YR QS V 567
Cdd:PRK06131 467 S D A R M SGTA YGTVV L HVA PE A AAGG P LA LV RTGD R IR L D VPARRLDL LV S DEELA R R R A AWP P PP P RAERGY Q EL YR DH V 546
570 580
....*....|....*....|....*..
gi 1376268663 568 T Q LSD G AVLEGAADF R RIA ek M PR HN H 594
Cdd:PRK06131 547 L Q ADE G CDFDFLVGY R GAP -- V PR DS H 571
ILVD_EDD
pfam00920 Dehydratase family;
47-574
0e+00
Dehydratase family;
Pssm-ID: 459998
Cd Length: 513
Bit Score: 670.58
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 47 KP V IGIA Q S G SDL T PC NRVHV EL VKR V RD G I R D AGG I P I EF P T HP ------ M FENCK R pt AA L D - R N L AYL S LV E V L YGY 119
Cdd:pfam00920 1 KP I IGIA N S Y SDL V PC HVHLR EL AEA V KE G V R E AGG V P A EF N T IG vcdgia M GHEGM R -- YS L P s R E L IAD S IE E M L RAH 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 120 P L DG V VL TT GCDK TT P SA LMAA STVD IPAI VL SGGPML D G yhegdlv GSGT VIWRMRRK Y G AG E I TR EE F L QAALESA P S 199
Cdd:pfam00920 79 P F DG L VL IG GCDK IV P GM LMAA ARLN IPAI FV SGGPML P G ------- GSGT DEFEAVGA Y A AG K I SE EE L L EIERAAC P G 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 200 V G H C NT MGTA S TM NAI AEALG M SL T G CGA IPA AYR ER GQM A YRT GRR A VELV V E N IKP S DI M TR E AF L NAI R V NS A I GGS 279
Cdd:pfam00920 152 C G S C GG MGTA N TM ACL AEALG L SL P G SAT IPA VSA ER LRL A REA GRR I VELV E E D IKP R DI L TR K AF E NAI V V DM A L GGS 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 280 TNA QP HL A A M A KH AGV E L REE D WQVHGYDI PLLA NIQ P A GK W L G E KY HRAGG T PA IMW ELL Q A g K L D G SCR TVTG R T VA E 359
Cdd:pfam00920 232 TNA VL HL L A I A RE AGV D L TLD D FDRISRKV PLLA DLK P S GK Y L M E DF HRAGG V PA VLK ELL D A - L L H G DVL TVTG K T LG E 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 360 NL EGR E ST D R DVI L P Y D K P LKERA G FL VLKGNL F - D F A IM KTS VISA E FRQ rylnepghegi FEG RCV VFD GS ED YH A R I 438
Cdd:pfam00920 311 NL ADA E VR D Q DVI R P L D N P ISPTG G LA VLKGNL A p D G A VV KTS AVDP E MLV ----------- FEG PAR VFD SE ED AL A A I 379
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 439 N D P sl D I DERTIL VIR GA GP L G W PG SA E V vn MQ P PD ALL KK G I - TSLPT I G DGR Q SG TADS PSI LNA SPE S A A GG GL A WL 517
Cdd:pfam00920 380 L D G -- K I KAGDVV VIR YE GP K G G PG MP E M -- LT P TS ALL GA G L g KDVAL I T DGR F SG ASRG PSI GHV SPE A A V GG PI A LV 455
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 1376268663 518 R T GD V IRID FNKGECNV LV P DEELAAR K A DGI P AV P - ADATPWQRI Y RQS V TQL S D GA 574
Cdd:pfam00920 456 R D GD I IRID IPNRTLDL LV S DEELAAR R A AWK P PE P k VKGRGYLAK Y AKL V SSA S E GA 513
PRK13016
PRK13016 dihydroxy-acid dehydratase; Provisional
5-574
8.93e-178
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237271
Cd Length: 577
Bit Score: 515.05
E-value: 8.93e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 5 KTP m RR LRS QD WF d N PD H L DMTA l YLE R F M NY G VT PE ELR s GKPVI G I AQSG SD LT PC NRVHV E L V KR V RD G IRD AGG I P 84
Cdd:PRK13016 4 KTP - EE LRS AR WF - G PD D L RSFG - HRS R M M QM G YA PE DFD - GKPVI A I LNTW SD AN PC HGHFR E R V ED V KR G VLQ AGG F P 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 85 I E F P THPMF EN CKR PT AA L D RNL AYLSLV E VLYGY P L DG V VL TT GCDKTTP SAL M A A STVDI P A I V L SG GPML D G YHE G D 164
Cdd:PRK13016 80 L E L P ALSLS EN FVK PT TM L Y RNL LAMETE E LIRSH P V DG A VL MG GCDKTTP GLV M G A ISMGL P M I Y L PA GPML R G NYR G K 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 165 LV GSG TVI W R --- M RR kyg AG E IT RE E F L QAALES A P S V G H C N TMGTASTM N AIAEALG MS L T G CGA IPAA YRERGQ MA Y 241
Cdd:PRK13016 160 VL GSG SDA W K ywd E RR --- AG N IT QA E W L EIEGGI A R S Y G T C M TMGTASTM T AIAEALG LT L P G ASS IPAA DANHQR MA A 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 242 RT GRR A VE L V V E NIK PS D I M T RE AF L NAI R V NS A I G G STNA QP HL A AMA KH AGV E L REE D WQVH G YDI P LL ANI Q P A GK - 320
Cdd:PRK13016 237 LC GRR I VE M V W E DLT PS Q I L T KA AF E NAI T V AM A T G C STNA VI HL I AMA RR AGV P L SLD D LDRC G RTV P VI ANI R P S GK t 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 321 W L G E KYHR AGG TP A I M WE L lq AG KL DGSCR TVTG R T VAE NLEG RESTDR DVI L P Y D K P LKERAGFL VL K GNL F - D F A IM K 399
Cdd:PRK13016 317 Y L M E DFFY AGG LR A L M KQ L -- GD KL HLDAL TVTG K T LGD NLEG AKVYND DVI R P L D N P VYAEGSLA VL R GNL A p D G A VI K 394
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 400 TSVISAE F RQR ylnepghegif E G RCV VFD GSEDYH A R I N D PS LD IDERTIL V I R G AGP L G W PG SA E VVNMQP P DA LLK K 479
Cdd:PRK13016 395 PAACDPK F LVH ----------- R G PAL VFD SYPEMK A A I D D EN LD VTPDHVM V L R N AGP Q G G PG MP E WGMLPI P KK LLK Q 463
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 480 G ITSLPT I G D G R Q SGT ADSPSI L NAS PE SAA GG G LA WL RTGD V I RI D FNKGECNV LV P DEELA A R K A DGI P AVPADATPW 559
Cdd:PRK13016 464 G VRDMVR I S D A R M SGT SYGACV L HVA PE AYV GG P LA LV RTGD I I EL D VPARRLHL LV S DEELA R R R A AWQ P PERRYERGY 543
570
....*....|....*
gi 1376268663 560 QRIYR Q S V T Q LSD G A 574
Cdd:PRK13016 544 GWMFS Q H V E Q ADK G C 558
IlvD
COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, ...
8-577
2.24e-158
Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; Dihydroxyacid dehydratase/phosphogluconate dehydratase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439899
Cd Length: 558
Bit Score: 464.87
E-value: 2.24e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 8 M RRL RS QDWFDNPDHLDMT AL Y le R FM ny G V T P E EL rs GKP V IGIA Q S GSDLT P CN r VH V - E L VKR V RD GIR D AGG I P I E 86
Cdd:COG0129 1 M PKM RS DTVTKGRERAPAR AL L -- R AT -- G L T D E DF -- GKP I IGIA N S WNEIV P GH - VH L d D L AEA V KE GIR A AGG V P F E 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 87 F P T hpmfenckrpt A A LDRNL A ------- Y l SL --------- V E - VLYGYPL DG V V LTT GCDK T TP SA LMAA STVD IP A I 149
Cdd:COG0129 74 F N T ----------- I A VSDGI A mghegmr Y - SL psreliads I E t MVNAHCF DG L V CIP GCDK I TP GM LMAA ARLN IP S I 141
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 150 VLS GGPML D G YHE G --------- DL VG sgtviwrmrr K Y G AG E I TR EE FLQAALESA P SV G H C NT M G TA S TM NAIA EALG 220
Cdd:COG0129 142 FVY GGPML P G KYD G kdldivdvf EA VG ---------- A Y A AG K I SD EE LKEIERNAC P GC G S C SG M F TA N TM ACLT EALG 211
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 221 M SL T G C G A IPA AYR ER GQM A YRT GRR A VELV VEN IKP S DI M TREAF L NAI R V NS A I GGSTN AQP HL A A M A KH AGV E L REE 300
Cdd:COG0129 212 L SL P G S G T IPA VSA ER RRL A REA GRR I VELV EKD IKP R DI L TREAF E NAI A V DM A L GGSTN TVL HL L A I A HE AGV D L TLD 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 301 D WQVHGYDI P L L ANIQ P A GK WLG E KY HRAGG T PA I M W ELL Q AG K L D G S C R TVTG R T V AENL EG - REST D R DVI L P Y D K P L 379
Cdd:COG0129 292 D FDRISRRT P H L CDLK P S GK YHM E DL HRAGG I PA V M K ELL D AG L L H G D C L TVTG K T L AENL AD a DIDR D Q DVI R P L D N P Y 371
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 380 KERA G FLV L K GNL F - D F A IM KT SVISAEFRQ rylnepghegi FEG RCV VFD GS E DYHAR I NDP sl D I DERTIL VIR GA GP 458
Cdd:COG0129 372 SPTG G LAI L R GNL A p D G A VV KT AGVDESMLV ----------- FEG PAR VFD SE E EAVEA I LGG -- K I KAGDVV VIR YE GP 438
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 459 L G W PG SA E vvn M QP P DAL LK - K G ------- IT slptig DGR Q SG TADSP SI LNA SPE S A A GG GL A WLRT GD V I R ID FNKG 530
Cdd:COG0129 439 K G G PG MR E --- M LS P TSA LK g M G lgksval IT ------ DGR F SG GTRGL SI GHV SPE A A E GG PI A LVED GD I I T ID IPAR 509
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 1376268663 531 ECNV LV P DEELA A R K A DGI P AV P ADATPWQRI Y RQS V TQL S D GAV LE 577
Cdd:COG0129 510 TLDL LV S DEELA R R R A AWK P PE P RVTSGVLAK Y AKL V SSA S K GAV TD 556
PRK00911
PRK00911 dihydroxy-acid dehydratase; Provisional
37-577
3.22e-153
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 234861
Cd Length: 552
Bit Score: 451.44
E-value: 3.22e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 37 G V T P E ELR sg KP V IGIA Q S GSDL TPCN r V H V - EL VKR V RD G I R D AGG I P I EF P T ---------- H P - M fenckrptaald 104
Cdd:PRK00911 23 G L T D E DFD -- KP F IGIA N S WNEI TPCN - I H L n EL ADA V KE G V R A AGG V P F EF N T igvsdgiamg H E g M ------------ 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 105 rnla YL SL --------- V E - V LYGYPL DG V V LTT GCDK TT P SA LMAA STVDI P A I VLS GGP M L D G YHE G --- D L ------ 165
Cdd:PRK00911 88 ---- KY SL vsreviads I E t V VNAHWF DG L V AIP GCDK NM P GM LMAA ARLNV P S I FVY GGP I L P G RLK G kdl T L vsvfea 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 166 VG sgtviwrmrr K Y G AG E I TR EE FL qa AL E SA -- P SV G H C NT M G TA S TM NAIA EALGMSL T G C G A IPA AYR ER GQM A YRT 243
Cdd:PRK00911 164 VG ---------- A Y A AG K I SE EE LK -- EI E RN ac P GA G S C GG M F TA N TM ACLI EALGMSL P G S G T IPA VDA ER DEL A REA 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 244 G RRA VEL VVEN IKP S DI M TREAF L NAI R V NS A I GGSTNA QP HL A A M A KH AGV E L REE D WQVHGYDI P L LA NIQ P A GK WLG 323
Cdd:PRK00911 232 G EAV VEL LEKD IKP R DI L TREAF E NAI A V DM A L GGSTNA VL HL L A I A HE AGV D L TLD D FNRISKRT P H LA DLK P S GK YVM 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 324 E KY H R AGG T PA I M W ELL Q AG K L D G S C R TVTG R T V AENL EGREST D R DVI L P Y D K P LKERA G FLV LKGNL F - DF A IM K TSV 402
Cdd:PRK00911 312 E DL H E AGG I PA V M K ELL D AG L L H G D C L TVTG K T L AENL ADAPDP D Q DVI R P L D N P ISPTG G LAI LKGNL A p EG A VV K IAG 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 403 ISA E frqrylnepgheg I F E G RCV VFD GS E DYHAR I NDP sl D I DERTIL VIR GA GP L G W PG SA E vvn M QP P DALLK - K G - 480
Cdd:PRK00911 392 VKP E ------------- M F T G PAR VFD SE E EAMEA I LAG -- K I KAGDVV VIR YE GP K G G PG MR E --- M LA P TSAIV g A G l 453
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 481 ------ IT slptig DGR Q SG TADSPSILNA SPE S A A GG GL A WLRT GD V I R ID FNKGECN VLV P DEELA A R K A DGI P AV P A 554
Cdd:PRK00911 454 gddval IT ------ DGR F SG GTRGLCVGHV SPE A A V GG PI A LVED GD I I T ID APNRTLD VLV S DEELA R R R A AWK P PE P K 527
570 580
....*....|....*....|...
gi 1376268663 555 DATPWQRI Y RQS V TQL S D GAV LE 577
Cdd:PRK00911 528 YKRGVLAK Y AKL V SSA S T GAV TD 550
ilvD
TIGR00110 dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth ...
37-576
3.04e-123
dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth step in valine and isoleucine biosynthesis. It contains a catalytically essential [4Fe-4S] cluster This model generates scores of up to 150 bits vs. 6-phosphogluconate dehydratase, a homologous enzyme. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272910
Cd Length: 535
Bit Score: 374.06
E-value: 3.04e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 37 G V T P E EL rs GKP V IG I A Q S GSDLT P CN r V H V - E L VKR V RD GI RD AGG IPI EF P T HPMFENCKRPTAAL ----- D R NLAYL 110
Cdd:TIGR00110 3 G F T D E DF -- GKP F IG V A N S YTTIV P GH - M H L r D L AQA V KE GI EA AGG VAF EF N T IAVCDGIAMGHEGM kyslp S R EIIAD 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 111 S LVEVLYGYPL DG V V LTTG CDK T TP SA LMAA STVD IP A I VLS GGPML D G - YHE G DLVGSGTVIWRM r RK Y G AG E I TR EE F 189
Cdd:TIGR00110 80 S VETMVNAHRF DG L V CIPS CDK I TP GM LMAA ARLN IP S I FVT GGPML P G h TKL G KKIDLVSAFEAV - GE Y A AG K I SE EE L 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 190 LQAALESA P SV G H C NT M G TA S TM NAIA EALG M SL T GC GAIP A AYR E RGQM A YRT G R R A VELV VE NIKP S DI M T R EAF L NA 269
Cdd:TIGR00110 159 EEIERSAC P GC G S C SG M F TA N TM ACLT EALG L SL P GC STML A TSA E KKRI A KNS G K R I VELV KK NIKP R DI L T K EAF E NA 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 270 I R V NS A I GGSTN AQP HL A A M A KH AGV E L REE D WQVHGYDI P LL A NIQ P A GK WLG E KY HRAGG T PA IMW EL LQA G K L D G SC 349
Cdd:TIGR00110 239 I T V DM A L GGSTN TVL HL L A I A NE AGV D L SLD D FDRLSRKV P HI A SLA P S GK YVM E DL HRAGG I PA VLK EL DRE G L L H G DT 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 350 R TVTG R T VA E N LE GRES -- TDR DVI L P Y D K P LKERA G FLV LKGNL F - DF A IM K TSVIS aefrqrylnepgh E GI -- FEG R 424
Cdd:TIGR00110 319 L TVTG K T LG E I LE QAPV ip EGQ DVI R P L D N P VHQEG G LAI LKGNL A p NG A VV K IAGVD ------------- E DM tk FEG P 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 425 CV VF DGS E DYHAR I NDP sl D I D E RTIL VIR GA GP L G W PG SA E VVN mq P PD A LLKK G I - T S LPT I G DGR Q SG TADSPS I LN 503
Cdd:TIGR00110 386 AK VF ESE E EALEA I LGG -- K I K E GDVV VIR YE GP K G G PG MP E MLA -- P TS A IKGM G L g K S VAL I T DGR F SG GTRGLC I GH 461
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1376268663 504 A SPE S A A GG GL A WLRT GD V I R ID FNKGECNVL V P DEELA A R K A DGIPAV P ADATPWQRI Y RQS V TQLSD GAVL 576
Cdd:TIGR00110 462 V SPE A A E GG PI A LVED GD I I I ID IPNRKLDLQ V S DEELA E R R A SWKAPE P RYVKGYLAK Y AKL V SSADE GAVL 534
PRK12448
PRK12448 dihydroxy-acid dehydratase; Provisional
46-546
4.59e-66
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237104
Cd Length: 615
Bit Score: 226.65
E-value: 4.59e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 46 GKP V I GIAQ S GSDLT P c NR VH V - E L VKR V RDG I RD AGG IPI EF pthpmfe N ckrp T A A L D RNL A ------- Y l SL ----- 112
Cdd:PRK12448 32 GKP I I AVVN S FTQFV P - GH VH L k D L GQL V ARE I EA AGG VAK EF ------- N ---- T I A V D DGI A mghggml Y - SL psrel 98
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 113 ---- VE - VLYGYPL D GV V LTTG CDK T TP SA LMAA STVD IP AIVL SGGPM ------- L D GYHEG DLV GSGTV iwrmrrky G 180
Cdd:PRK12448 99 iads VE y MVNAHCA D AM V CISN CDK I TP GM LMAA LRLN IP VVFV SGGPM eagktkl S D KIIKL DLV DAMVA -------- A 170
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 181 A GEITRE E FLQAALE SA - P SV G H C NT M G TA ST MN AIA EALG M SL T G C G AIP A AYRE R G Q MAYRT GRR A VEL VV ------- 252
Cdd:PRK12448 171 A DPSVSD E DVAQIER SA c P TC G S C SG M F TA NS MN CLT EALG L SL P G N G SLL A THAD R K Q LFLEA GRR I VEL AK ryyeqdd 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 253 E NIK P SD I M T RE AF L NA IRVNS A I GGSTN AQP HL A A M A KH A G V ELREE D WQVHGYDI P L L ANIQ P A - G K WLG E KY HRAGG 331
Cdd:PRK12448 251 E SVL P RS I A T KA AF E NA MTLDI A M GGSTN TVL HL L A A A QE A E V DFTMA D IDRLSRKV P C L CKVA P N t Q K YHM E DV HRAGG 330
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 332 TPA I MW EL LQ AG K L DGSCR TV T G R T VA E N L E --------------------- G RES T ------------ D R D ---- V I LP 374
Cdd:PRK12448 331 IMG I LG EL DR AG L L HTDVP TV H G L T LG E A L D qwdimrtqdeavkeffraapg G IRT T vafsqdcrwdsl D T D reng C I RS 410
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 375 YDKPLKERA G FL VL K GN L - F D FA I M KT SVI saefrqrylnepg H E G I -- F E G RCV VF DGSE D YHAR I - ND psl DIDERTI 450
Cdd:PRK12448 411 VEHAYSKDG G LA VL Y GN I a E D GC I V KT AGV ------------- D E S I lk F T G PAR VF ESQD D AVEA I l GG --- KVKAGDV 474
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376268663 451 L VIR GA GP L G W PG SA E vvn M QP P DAL LK - KG I - TSLPT I G DGR Q SG TADSP SI LNA SPE S A A GG GLAWLRT GD V I R ID FN 528
Cdd:PRK12448 475 V VIR YE GP K G G PG MQ E --- M LY P TSY LK s KG L g KACAL I T DGR F SG GTSGL SI GHV SPE A A S GG AIGLVED GD I I E ID IP 551
570
....*....|....*...
gi 1376268663 529 KGEC N V LV P DEELAAR K A 546
Cdd:PRK12448 552 NRSI N L LV S DEELAAR R A 569
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
