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Conserved domains on  [gi|1382304969|ref|WP_108167409|]
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methyl-accepting chemotaxis protein [Vibrio splendidus]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
17-545 8.98e-82

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 264.96  E-value: 8.98e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  17 MVIVIVFSTVTVLNVIRSNAQAAINHELNNVVQPVLDNLEDGYRDIYQVIASAQGLLLAKDQAAIEYQKFEFKDNAYKAV 96
Cdd:COG0840    10 LLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  97 PRFESVETLYAAGVLDPSSRSELSKLVNAMSKWVALHEPMFADPASAYQYNINYSPALDAEFAIIRVQLRDIRTLIEQKQ 176
Cdd:COG0840    90 LLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEA 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 177 KELRQQAADSIEsskLIIEVGMAVAVFAAFFAMWLSNRFIVQPIQNVEKAMNEIASGDgnLSQRMKVEGNDEIARLSSAF 256
Cdd:COG0840   170 AALALAAAALAL---ALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGD--LTVRIDVDSKDEIGQLADAF 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 257 NQFVGKIHVTVEQVILTSNAVRGEMENIKSLTQSVAEFSSNQQRESEVVAAAVHEMQATSEVVSGNALDAATASNVANHE 336
Cdd:COG0840   245 NRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASEL 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 337 VESADKTLGLTVTSIERLAQDIENAGGVVQELDTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADE 416
Cdd:COG0840   325 AEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADE 404

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 417 VRALASKTQDSTGEIQSMIERLEVGAKHAVGVMTESKVSGEKTIVQAGTAASSLSEIRNSIGKMNDMNTQIATAASQQSQ 496
Cdd:COG0840   405 VRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSA 484

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 1382304969 497 VSEEVNKNVQRIAESTLQMVEMASSAENACMALAEQCEALDSLVSQFEV 545
Cdd:COG0840   485 GTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
17-545 8.98e-82

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 264.96  E-value: 8.98e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  17 MVIVIVFSTVTVLNVIRSNAQAAINHELNNVVQPVLDNLEDGYRDIYQVIASAQGLLLAKDQAAIEYQKFEFKDNAYKAV 96
Cdd:COG0840    10 LLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  97 PRFESVETLYAAGVLDPSSRSELSKLVNAMSKWVALHEPMFADPASAYQYNINYSPALDAEFAIIRVQLRDIRTLIEQKQ 176
Cdd:COG0840    90 LLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEA 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 177 KELRQQAADSIEsskLIIEVGMAVAVFAAFFAMWLSNRFIVQPIQNVEKAMNEIASGDgnLSQRMKVEGNDEIARLSSAF 256
Cdd:COG0840   170 AALALAAAALAL---ALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGD--LTVRIDVDSKDEIGQLADAF 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 257 NQFVGKIHVTVEQVILTSNAVRGEMENIKSLTQSVAEFSSNQQRESEVVAAAVHEMQATSEVVSGNALDAATASNVANHE 336
Cdd:COG0840   245 NRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASEL 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 337 VESADKTLGLTVTSIERLAQDIENAGGVVQELDTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADE 416
Cdd:COG0840   325 AEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADE 404

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 417 VRALASKTQDSTGEIQSMIERLEVGAKHAVGVMTESKVSGEKTIVQAGTAASSLSEIRNSIGKMNDMNTQIATAASQQSQ 496
Cdd:COG0840   405 VRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSA 484

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 1382304969 497 VSEEVNKNVQRIAESTLQMVEMASSAENACMALAEQCEALDSLVSQFEV 545
Cdd:COG0840   485 GTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 283-543 5.35e-59

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 196.74  E-value: 5.35e-59
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  283 NIKSLTQSVAEFSSNQQRESEVVAAAVHEMQATSEVVSGNALDAATASNVANHEVESADKTLGLTVTSIERLAQDIENAG 362
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  363 GVVQELDTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQDSTGEIQSMIERLEVGA 442
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEET 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  443 KHAVGVMTESKVSGEKTIVQAGTAASSLSEIRNSIGKMNDMNTQIATAASQQSQVSEEVNKNVQRIAESTLQMVEMASSA 522
Cdd:smart00283 161 NEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|.
gi 1382304969  523 ENACMALAEQCEALDSLVSQF 543
Cdd:smart00283 241 SAAAEELSGLAEELDELVERF 261
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 310-509 1.29e-47

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 164.33  E-value: 1.29e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 310 HEMQATSEVVSGNALDAATASNVANHEVESADKTLGLTVTSIERLAQDIENAGGVVQELDTDVKNIASILGVIKGIAEQT 389
Cdd:cd11386     1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 390 NLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQDSTGEIQSMIERLEVGAKHAVGVMTESKVSGEKTIVQAGTAASS 469
Cdd:cd11386    81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1382304969 470 LSEIRNSIGKMNDMNTQIATAASQQSQVSEEVNKNVQRIA 509
Cdd:cd11386   161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
172-545 7.81e-39

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 149.07  E-value: 7.81e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 172 IEQKQKELRQQAADSIESSKLIIEVGMAVAVFAAFFAMWLSNRFIVQPIQNVEKAMNEIAsgDGNLSQRMKVEGNDEIAR 251
Cdd:PRK09793  170 INHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPLAIIGSHFDSIA--AGNLARPIAVYGRNEITA 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 252 LSSAFNQFVGKIHVTVEQVILTSNAVRgemENIKSLTQSVAEFSSNQQRESEVVAAAVHEMQATSEVVSGNALDAATASN 331
Cdd:PRK09793  248 IFASLKTMQQALRGTVSDVRKGSQEMH---IGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASE 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 332 VANHEVESADKTlGLTVTSIERLAQDIEnaggvvqeldTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFA 411
Cdd:PRK09793  325 LAKNAATTAQAG-GVQVSTMTHTMQEIA----------TSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFA 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 412 VVADEVRALASKTQDSTGEIQSMIERlevgakhavgvmTESKVSGEKTIVQagTAASSLSEIRNSIGKMNDMNTQIATAA 491
Cdd:PRK09793  394 VVAGEVRNLASRSAQAAKEIKGLIEE------------SVNRVQQGSKLVN--NAAATMTDIVSSVTRVNDIMGEIASAS 459

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1382304969 492 SQQSQVSEEVNKNVQRIAESTLQMVEMASSAENACMALAEQCEALDSLVSQFEV 545
Cdd:PRK09793  460 EEQRRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVAVFTL 513
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 356-512 8.60e-38

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 137.18  E-value: 8.60e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 356 QDIENAGGVVQELDTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQDSTGEIQSMI 435
Cdd:pfam00015  16 KEVANVVGQMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEIEALI 95

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1382304969 436 ERLEVGAKHAVGVMTESKVSGEKTIVQAGTAASSLSEIRNSIGKMNDMNTQIATAASQQSQVSEEVNKNVQRIAEST 512
Cdd:pfam00015  96 IEIQKQTNDSTASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVARMDQVT 172
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
17-545 8.98e-82

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 264.96  E-value: 8.98e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  17 MVIVIVFSTVTVLNVIRSNAQAAINHELNNVVQPVLDNLEDGYRDIYQVIASAQGLLLAKDQAAIEYQKFEFKDNAYKAV 96
Cdd:COG0840    10 LLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  97 PRFESVETLYAAGVLDPSSRSELSKLVNAMSKWVALHEPMFADPASAYQYNINYSPALDAEFAIIRVQLRDIRTLIEQKQ 176
Cdd:COG0840    90 LLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEA 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 177 KELRQQAADSIEsskLIIEVGMAVAVFAAFFAMWLSNRFIVQPIQNVEKAMNEIASGDgnLSQRMKVEGNDEIARLSSAF 256
Cdd:COG0840   170 AALALAAAALAL---ALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGD--LTVRIDVDSKDEIGQLADAF 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 257 NQFVGKIHVTVEQVILTSNAVRGEMENIKSLTQSVAEFSSNQQRESEVVAAAVHEMQATSEVVSGNALDAATASNVANHE 336
Cdd:COG0840   245 NRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASEL 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 337 VESADKTLGLTVTSIERLAQDIENAGGVVQELDTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADE 416
Cdd:COG0840   325 AEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADE 404

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 417 VRALASKTQDSTGEIQSMIERLEVGAKHAVGVMTESKVSGEKTIVQAGTAASSLSEIRNSIGKMNDMNTQIATAASQQSQ 496
Cdd:COG0840   405 VRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSA 484

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 1382304969 497 VSEEVNKNVQRIAESTLQMVEMASSAENACMALAEQCEALDSLVSQFEV 545
Cdd:COG0840   485 GTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 283-543 5.35e-59

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 196.74  E-value: 5.35e-59
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  283 NIKSLTQSVAEFSSNQQRESEVVAAAVHEMQATSEVVSGNALDAATASNVANHEVESADKTLGLTVTSIERLAQDIENAG 362
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  363 GVVQELDTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQDSTGEIQSMIERLEVGA 442
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEET 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969  443 KHAVGVMTESKVSGEKTIVQAGTAASSLSEIRNSIGKMNDMNTQIATAASQQSQVSEEVNKNVQRIAESTLQMVEMASSA 522
Cdd:smart00283 161 NEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|.
gi 1382304969  523 ENACMALAEQCEALDSLVSQF 543
Cdd:smart00283 241 SAAAEELSGLAEELDELVERF 261
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 310-509 1.29e-47

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 164.33  E-value: 1.29e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 310 HEMQATSEVVSGNALDAATASNVANHEVESADKTLGLTVTSIERLAQDIENAGGVVQELDTDVKNIASILGVIKGIAEQT 389
Cdd:cd11386     1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 390 NLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQDSTGEIQSMIERLEVGAKHAVGVMTESKVSGEKTIVQAGTAASS 469
Cdd:cd11386    81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1382304969 470 LSEIRNSIGKMNDMNTQIATAASQQSQVSEEVNKNVQRIA 509
Cdd:cd11386   161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
172-545 7.81e-39

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 149.07  E-value: 7.81e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 172 IEQKQKELRQQAADSIESSKLIIEVGMAVAVFAAFFAMWLSNRFIVQPIQNVEKAMNEIAsgDGNLSQRMKVEGNDEIAR 251
Cdd:PRK09793  170 INHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPLAIIGSHFDSIA--AGNLARPIAVYGRNEITA 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 252 LSSAFNQFVGKIHVTVEQVILTSNAVRgemENIKSLTQSVAEFSSNQQRESEVVAAAVHEMQATSEVVSGNALDAATASN 331
Cdd:PRK09793  248 IFASLKTMQQALRGTVSDVRKGSQEMH---IGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASE 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 332 VANHEVESADKTlGLTVTSIERLAQDIEnaggvvqeldTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFA 411
Cdd:PRK09793  325 LAKNAATTAQAG-GVQVSTMTHTMQEIA----------TSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFA 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 412 VVADEVRALASKTQDSTGEIQSMIERlevgakhavgvmTESKVSGEKTIVQagTAASSLSEIRNSIGKMNDMNTQIATAA 491
Cdd:PRK09793  394 VVAGEVRNLASRSAQAAKEIKGLIEE------------SVNRVQQGSKLVN--NAAATMTDIVSSVTRVNDIMGEIASAS 459

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1382304969 492 SQQSQVSEEVNKNVQRIAESTLQMVEMASSAENACMALAEQCEALDSLVSQFEV 545
Cdd:PRK09793  460 EEQRRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVAVFTL 513
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 356-512 8.60e-38

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 137.18  E-value: 8.60e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 356 QDIENAGGVVQELDTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQDSTGEIQSMI 435
Cdd:pfam00015  16 KEVANVVGQMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEIEALI 95

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1382304969 436 ERLEVGAKHAVGVMTESKVSGEKTIVQAGTAASSLSEIRNSIGKMNDMNTQIATAASQQSQVSEEVNKNVQRIAEST 512
Cdd:pfam00015  96 IEIQKQTNDSTASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVARMDQVT 172
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 214-543 1.46e-35

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 140.14  E-value: 1.46e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 214 RFIVQPIQNVEKAMNEIASGdgNLSQRMKVEGNDEIARLSSAFNQFVGKIHVTVEQVILTSNAVRGEMENIKSLTQSVAE 293
Cdd:PRK15048  214 RMLLTPLAKIIAHIREIAGG--NLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSS 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 294 FSSNQQRESEVVAAAVHEMQATsevVSGNALDAATASNVANHEVESADKTlGLTVTSIERLAQDIENAGgvvqeldtdvK 373
Cdd:PRK15048  292 RTEQQASALEETAASMEQLTAT---VKQNADNARQASQLAQSASDTAQHG-GKVVDGVVKTMHEIADSS----------K 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 374 NIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQDSTGEIQSMIE----RLEVGAkhavgVM 449
Cdd:PRK15048  358 KIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIEdsvsRVDTGS-----VL 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 450 TESkvsgektivqagtAASSLSEIRNSIGKMNDMNTQIATAASQQSQVSEEVNKNVQRIAESTLQMVEMASSAENACMAL 529
Cdd:PRK15048  433 VES-------------AGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAAL 499

                         330
                  ....*....|....
gi 1382304969 530 AEQCEALDSLVSQF 543
Cdd:PRK15048  500 EEQASRLTQAVSAF 513
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
216-545 1.75e-35

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 139.70  E-value: 1.75e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 216 IVQPIQNVEKAMNEIASGDgnLSQRMKVEGNDEIARLSSAFNQFVGKIHVTVEQVILTSNAVRGEMENIKSLTQSVAEFS 295
Cdd:PRK15041  218 LVAPMNRLIDSIRHIAGGD--LVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRT 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 296 SNQQRESEVVAAAVHEMQATsevVSGNALDAATASNVANHEVESADKTlGLTVTSIERLAQDIEnaggvvqeldTDVKNI 375
Cdd:PRK15041  296 EQQAASLEETAASMEQLTAT---VKQNAENARQASHLALSASETAQRG-GKVVDNVVQTMRDIS----------TSSQKI 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 376 ASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQDSTGEIQSMIERlevgakhavgvmTESKVS 455
Cdd:PRK15041  362 ADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIED------------SVGKVD 429

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 456 GEKTIVQagTAASSLSEIRNSIGKMNDMNTQIATAASQQSQVSEEVNKNVQRIAESTLQMVEMASSAENACMALAEQCEA 535
Cdd:PRK15041  430 VGSTLVE--SAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASR 507

                         330
                  ....*....|
gi 1382304969 536 LDSLVSQFEV 545
Cdd:PRK15041  508 LTEAVAVFRI 517
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 217-263 1.75e-10

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 56.30  E-value: 1.75e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1382304969 217 VQPIQNVEKAMNEIASGDgnLSQRMKVEGNDEIARLSSAFNQFVGKI 263
Cdd:cd06225     1 TRPLRRLTEAARRIAEGD--LDVRVPVRSKDEIGELARAFNQMAERL 45
HAMP smart00304
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
214-268 1.07e-09

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;


Pssm-ID: 197640 [Multi-domain]  Cd Length: 53  Bit Score: 54.18  E-value: 1.07e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1382304969  214 RFIVQPIQNVEKAMNEIASGDgnLSQRMKVEGNDEIARLSSAFNQFVGKIHVTVE 268
Cdd:smart00304   1 RRLLRPLRRLAEAAQRIADGD--LTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
HAMP pfam00672
HAMP domain;
214-264 3.35e-09

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 52.63  E-value: 3.35e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1382304969 214 RFIVQPIQNVEKAMNEIASGDgnLSQRMKVEGNDEIARLSSAFNQFVGKIH 264
Cdd:pfam00672   4 RRILRPLRRLAEAARRIASGD--LDVRLPVSGRDEIGELARAFNQMAERLR 52
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 209-291 3.38e-07

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 52.66  E-value: 3.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 209 MWLSNRfIVQPIQNVEKAMNEIASGDgnLSQRMKVEGNDEIARLSSAFNQFVGKIhvtveqviltsNAVRGEMENIKSLT 288
Cdd:COG5000    27 LLLARR-LTRPLRRLAEATRAVAAGD--LSVRLPVTGDDEIGELARAFNRMTDQL-----------KEQREELEERRRYL 92


                  ...
gi 1382304969 289 QSV 291
Cdd:COG5000    93 ETI 95
NarQ COG3850
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ...
 209-474 1.47e-04

Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];


Pssm-ID: 443059 [Multi-domain]  Cd Length: 448  Bit Score: 44.49  E-value: 1.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 209 MWLSNRFIVQPIQNVEKAMNEIASGDgnLSQRMKVEGNDEIARLSSAFNQFVGKIHVTVEQviLTSNAVRGEMENIKSLT 288
Cdd:COG3850   135 AYLLRRRIVRPLRRLTQAAERIARGD--FDARVPVSGRDELGTLARAFNRMADELQELYAE--LEEEEELEAELELLALL 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 289 QSVAEFSSNQQRESEVVAAAVHEMQATSEVVSGNALDAATASNVANHEVESADKTLGLTVTSIERLAQDIENAGGVVQEL 368
Cdd:COG3850   211 DELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLASALLLLELELLALLL 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 369 DTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQDSTGEIQSMIERLEVGAKHAVGV 448
Cdd:COG3850   291 ELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAALEAAAAGAALAAAAAAAG 370

                         250       260
                  ....*....|....*....|....*.
gi 1382304969 449 MTESKVSGEKTIVQAGTAASSLSEIR 474
Cdd:COG3850   371 LARALAQAGADAAEALGLLAEASEGA 396
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
209-545 7.21e-04

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 42.41  E-value: 7.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 209 MWLSNRFIVQPIQNVEKAMNEIASGDgnLSQRMKVEGNDEIARLSSAFNQFVGKIHVTVEQVILTSNAVRGEMENIKSLT 288
Cdd:COG2770   229 ALLLARRITRPLRRLAEAARRIAAGD--LDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEAL 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 289 QSVAEFssNQQRESEVVAAAVHEMQATSEVVSGNALDAATASNVANHEVESADKTLGLTVTSIERLAQDIENAGGVVQEL 368
Cdd:COG2770   307 LELLLA--LLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALAL 384

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 369 DTDVKNIASILGVIKGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTQDSTGEIQSMIERLEVGAKHAVGV 448
Cdd:COG2770   385 EAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEE 464

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 449 MTESKVSGEKTIVQAGTAASSLSEIRNSIGKMNDMNTQIATAASQQSQVSEEVNKNVQRIAESTLQMVEMASSAENACMA 528
Cdd:COG2770   465 LVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEELAEELLLLEGLLLLLLLEAEALEVAEELLELEEAALLLAA 544

                         330
                  ....*....|....*..
gi 1382304969 529 LAEQCEALDSLVSQFEV 545
Cdd:COG2770   545 AAELAALLALLLALAAV 561
YesM COG2972
Sensor histidine kinase YesM [Signal transduction mechanisms];
105-271 2.19e-03

Sensor histidine kinase YesM [Signal transduction mechanisms];


Pssm-ID: 442211 [Multi-domain]  Cd Length: 445  Bit Score: 40.77  E-value: 2.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 105 LYAAGVLDPSSRSELSKLVNAMSKWVALHEPMFADPASAYQYNINYSPALDAEFAIIRVQLRDIRTLIEQKQKELRQQAA 184
Cdd:COG2972    71 LLLLLLLALLLILLLLLLLLLLLILLLSLLLLLALILLLALLLLLSILLLILGLLLIILLLLSLLGWTLVSLIPKSELFR 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1382304969 185 DSIESSKLIIEVGMAVAVFAAFFAMWLSNRfIVQPIQNVEKAMNEIASGDGnlsQRMKVEGNDEIARLSSAFNQFVGKIH 264
Cdd:COG2972   151 GLFSLRRLILLIILLLLLLALLLSYLLSRS-ITRPIKRLKKAMKKVEKGDL---VRLEVSGNDEIGILARSFNEMVERIK 226


                  ....*..
gi 1382304969 265 VTVEQVI 271
Cdd:COG2972   227 ELIEEVY 233
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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