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Conserved domains on  [gi|1390623227|ref|WP_109127668|]
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DNA circularization protein [Aggregatibacter segnis]

Protein Classification

DNA circularization protein( domain architecture ID 10008371)

DNA circularization protein similar to Escherichia virus Mu DNA circularization protein N (gpN) that is required for tail assembly of phage Mu and is responsible for circularizing the viral DNA after it has been ejected into the host cell

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG4228 COG4228
Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];
1-462 6.43e-85

Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];


:

Pssm-ID: 443372 [Multi-domain]  Cd Length: 406  Bit Score: 266.54  E-value: 6.43e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227   1 MKGWTMPIQQASYRGVRFDVLSVDDNLERATITHAYPFVNGGDIEDLGLNPLTIQLQAVFYGEGYYTDFKRFLSALEKQG 80
Cdd:COG4228     1 MSSWRDKLQPASFRGVPFDVESADDSGGRRVAVHEYPYRDGPDVEDLGRKAREIRITAVVIGDDYLAQRDALLDALEQPG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227  81 AAVLVHPIRGRLQnMLCTSAYFHHEADFVDYVTVSLSFQEATPAkpifLFNFSVLGLIDELLTKLEDLVDDVLELYGFFM 160
Cdd:COG4228    81 PGELVHPYFGSLQ-VQVGEYSVRHSAEEGGYATFDLTFVEAGEG----AFPAALPDTQDALLAAADAALDAAGADFAAAF 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227 161 EGISFAANVKSRLLGSFGALYGCFEQVRDMFDMdkkkhgiSANTPTSKEAFKQQGGKAVRDMASMIrDGLTAIANRDDLT 240
Cdd:COG4228   156 SVLAVADGALADVLALAGALSGLVGALSRLAGP-------AAGLKSSLTDLLAAPAALAAALTGLV-DGLASLASSPADA 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227 241 VRAkFDEVTRTVKSLLEIAPNLSngknSKSNKLKSLTSSLTAQDTKEIFCAMQLLATATVLKIATQFIEDDSLVPseidy 320
Cdd:COG4228   228 IGA-LRSLSAGLSSDWDGNPAAS----PVPTPSATPSRPAAAQNQAAVAALVRRAALAELARAAAELLEAETETQ----- 297
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227 321 ivTESRLQALAtlntLRALVAEEqqamtlryakddfglmsLQAEkrngasRLQTPNTGlytqAYNTAEKLRQQSHKLTQL 400
Cdd:COG4228   298 --VLSPDDAQA----VRDALQAA-----------------LDAE------RADAADAG----DDAVYEALRDLRLALLQD 344
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1390623227 401 ALAAINRKPPLIIRTVEFDSTIQQVAHSFYGDYTRAGELLRLNpHIRYPNFIARGEVLNGYA 462
Cdd:COG4228   345 LAARAAALPPLVTRTVPATLPALVLAHRLYGDAARADELVRRN-GIRHPGFVPGGDLLEVLA 405
 
Name Accession Description Interval E-value
COG4228 COG4228
Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];
1-462 6.43e-85

Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];


Pssm-ID: 443372 [Multi-domain]  Cd Length: 406  Bit Score: 266.54  E-value: 6.43e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227   1 MKGWTMPIQQASYRGVRFDVLSVDDNLERATITHAYPFVNGGDIEDLGLNPLTIQLQAVFYGEGYYTDFKRFLSALEKQG 80
Cdd:COG4228     1 MSSWRDKLQPASFRGVPFDVESADDSGGRRVAVHEYPYRDGPDVEDLGRKAREIRITAVVIGDDYLAQRDALLDALEQPG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227  81 AAVLVHPIRGRLQnMLCTSAYFHHEADFVDYVTVSLSFQEATPAkpifLFNFSVLGLIDELLTKLEDLVDDVLELYGFFM 160
Cdd:COG4228    81 PGELVHPYFGSLQ-VQVGEYSVRHSAEEGGYATFDLTFVEAGEG----AFPAALPDTQDALLAAADAALDAAGADFAAAF 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227 161 EGISFAANVKSRLLGSFGALYGCFEQVRDMFDMdkkkhgiSANTPTSKEAFKQQGGKAVRDMASMIrDGLTAIANRDDLT 240
Cdd:COG4228   156 SVLAVADGALADVLALAGALSGLVGALSRLAGP-------AAGLKSSLTDLLAAPAALAAALTGLV-DGLASLASSPADA 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227 241 VRAkFDEVTRTVKSLLEIAPNLSngknSKSNKLKSLTSSLTAQDTKEIFCAMQLLATATVLKIATQFIEDDSLVPseidy 320
Cdd:COG4228   228 IGA-LRSLSAGLSSDWDGNPAAS----PVPTPSATPSRPAAAQNQAAVAALVRRAALAELARAAAELLEAETETQ----- 297
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227 321 ivTESRLQALAtlntLRALVAEEqqamtlryakddfglmsLQAEkrngasRLQTPNTGlytqAYNTAEKLRQQSHKLTQL 400
Cdd:COG4228   298 --VLSPDDAQA----VRDALQAA-----------------LDAE------RADAADAG----DDAVYEALRDLRLALLQD 344
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1390623227 401 ALAAINRKPPLIIRTVEFDSTIQQVAHSFYGDYTRAGELLRLNpHIRYPNFIARGEVLNGYA 462
Cdd:COG4228   345 LAARAAALPPLVTRTVPATLPALVLAHRLYGDAARADELVRRN-GIRHPGFVPGGDLLEVLA 405
DNA_circ_N pfam07157
DNA circularization protein N-terminus; This family represents the N-terminus (approximately ...
8-94 2.44e-36

DNA circularization protein N-terminus; This family represents the N-terminus (approximately 100 residues) of a number of phage DNA circularization proteins.


Pssm-ID: 462105  Cd Length: 88  Bit Score: 128.89  E-value: 2.44e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227   8 IQQASYRGVRFDVLSVDDNLERATITHAYPFVNGGDIEDLGLNPLTIQLQAVFYGEGYYTDFKRFLSALEKQGAAVLVHP 87
Cdd:pfam07157   2 LLDASFRGVPFEVEEADDSGGRRLAVHEYPYRDGPDVEDMGRKARRIRVQAYFVGDDYLDQRDALIDALEKPGPGELVHP 81

                  ....*..
gi 1390623227  88 IRGRLQN 94
Cdd:pfam07157  82 WLGSMTV 88
 
Name Accession Description Interval E-value
COG4228 COG4228
Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];
1-462 6.43e-85

Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];


Pssm-ID: 443372 [Multi-domain]  Cd Length: 406  Bit Score: 266.54  E-value: 6.43e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227   1 MKGWTMPIQQASYRGVRFDVLSVDDNLERATITHAYPFVNGGDIEDLGLNPLTIQLQAVFYGEGYYTDFKRFLSALEKQG 80
Cdd:COG4228     1 MSSWRDKLQPASFRGVPFDVESADDSGGRRVAVHEYPYRDGPDVEDLGRKAREIRITAVVIGDDYLAQRDALLDALEQPG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227  81 AAVLVHPIRGRLQnMLCTSAYFHHEADFVDYVTVSLSFQEATPAkpifLFNFSVLGLIDELLTKLEDLVDDVLELYGFFM 160
Cdd:COG4228    81 PGELVHPYFGSLQ-VQVGEYSVRHSAEEGGYATFDLTFVEAGEG----AFPAALPDTQDALLAAADAALDAAGADFAAAF 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227 161 EGISFAANVKSRLLGSFGALYGCFEQVRDMFDMdkkkhgiSANTPTSKEAFKQQGGKAVRDMASMIrDGLTAIANRDDLT 240
Cdd:COG4228   156 SVLAVADGALADVLALAGALSGLVGALSRLAGP-------AAGLKSSLTDLLAAPAALAAALTGLV-DGLASLASSPADA 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227 241 VRAkFDEVTRTVKSLLEIAPNLSngknSKSNKLKSLTSSLTAQDTKEIFCAMQLLATATVLKIATQFIEDDSLVPseidy 320
Cdd:COG4228   228 IGA-LRSLSAGLSSDWDGNPAAS----PVPTPSATPSRPAAAQNQAAVAALVRRAALAELARAAAELLEAETETQ----- 297
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227 321 ivTESRLQALAtlntLRALVAEEqqamtlryakddfglmsLQAEkrngasRLQTPNTGlytqAYNTAEKLRQQSHKLTQL 400
Cdd:COG4228   298 --VLSPDDAQA----VRDALQAA-----------------LDAE------RADAADAG----DDAVYEALRDLRLALLQD 344
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1390623227 401 ALAAINRKPPLIIRTVEFDSTIQQVAHSFYGDYTRAGELLRLNpHIRYPNFIARGEVLNGYA 462
Cdd:COG4228   345 LAARAAALPPLVTRTVPATLPALVLAHRLYGDAARADELVRRN-GIRHPGFVPGGDLLEVLA 405
DNA_circ_N pfam07157
DNA circularization protein N-terminus; This family represents the N-terminus (approximately ...
8-94 2.44e-36

DNA circularization protein N-terminus; This family represents the N-terminus (approximately 100 residues) of a number of phage DNA circularization proteins.


Pssm-ID: 462105  Cd Length: 88  Bit Score: 128.89  E-value: 2.44e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390623227   8 IQQASYRGVRFDVLSVDDNLERATITHAYPFVNGGDIEDLGLNPLTIQLQAVFYGEGYYTDFKRFLSALEKQGAAVLVHP 87
Cdd:pfam07157   2 LLDASFRGVPFEVEEADDSGGRRLAVHEYPYRDGPDVEDMGRKARRIRVQAYFVGDDYLDQRDALIDALEKPGPGELVHP 81

                  ....*..
gi 1390623227  88 IRGRLQN 94
Cdd:pfam07157  82 WLGSMTV 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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