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Conserved domains on  [gi|1398205114|ref|WP_110233190|]
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MULTISPECIES: zinc ribbon domain-containing protein [Aurantimicrobium]

Protein Classification

zinc ribbon domain-containing protein( domain architecture ID 11446337)

zinc ribbon domain-containing protein may bind nucleic acids; similar to Mycobacterium tuberculosis uncharacterized protein Rv2229c

CATH:  1.10.287.1490
PubMed:  32851833|21348639

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 5-241 3.56e-45

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


:

Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 151.23  E-value: 3.56e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   5 PEDQLALLTLQERDNHITQLNHARKNIaeQAELAEVTASLREFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIAKDKE 84
Cdd:COG1579     3 PEDLRALLDLQELDSELDRLEHRLKEL--PAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114  85 REAGAASAKDLQALEAELASLATRKSNLEDIELVVMQSIEDAEVAVADVLVERDAVEARRAALAQAVSTREAEIDAELAA 164
Cdd:COG1579    81 QLGNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEE 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1398205114 165 ETAARTELAASLPADLVELYERQRARY-GIGAALLTRRVTGGSGVELTSTDLDAVRAAapDDVVICPDSSCILVRTNE 241
Cdd:COG1579   161 LEAEREELAAKIPPELLALYERIRKRKnGLAVVPVEGGACGGCFMELPPQELNEIRAA--DEIVRCPNCGRILYREEE 236
 
Name Accession Description Interval E-value
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 5-241 3.56e-45

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 151.23  E-value: 3.56e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   5 PEDQLALLTLQERDNHITQLNHARKNIaeQAELAEVTASLREFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIAKDKE 84
Cdd:COG1579     3 PEDLRALLDLQELDSELDRLEHRLKEL--PAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114  85 REAGAASAKDLQALEAELASLATRKSNLEDIELVVMQSIEDAEVAVADVLVERDAVEARRAALAQAVSTREAEIDAELAA 164
Cdd:COG1579    81 QLGNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEE 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1398205114 165 ETAARTELAASLPADLVELYERQRARY-GIGAALLTRRVTGGSGVELTSTDLDAVRAAapDDVVICPDSSCILVRTNE 241
Cdd:COG1579   161 LEAEREELAAKIPPELLALYERIRKRKnGLAVVPVEGGACGGCFMELPPQELNEIRAA--DEIVRCPNCGRILYREEE 236
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 6-172 3.08e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 3.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114    6 EDQLALLTLQERDNHITQLNHARKNIAEQAELAEVTASLREFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIA--KDK 83
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnlERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   84 EREAGAASAKDLQALEAELASLATRKSNLEDIElvvmQSIEDAEVAVADVLVERDAVEARRAALAQAVSTREAEIDAELA 163
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELK----EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393


                   ....*....
gi 1398205114  164 AETAARTEL 172
Cdd:TIGR02168  394 QIASLNNEI 402
 
Name Accession Description Interval E-value
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 5-241 3.56e-45

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 151.23  E-value: 3.56e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   5 PEDQLALLTLQERDNHITQLNHARKNIaeQAELAEVTASLREFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIAKDKE 84
Cdd:COG1579     3 PEDLRALLDLQELDSELDRLEHRLKEL--PAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114  85 REAGAASAKDLQALEAELASLATRKSNLEDIELVVMQSIEDAEVAVADVLVERDAVEARRAALAQAVSTREAEIDAELAA 164
Cdd:COG1579    81 QLGNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEE 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1398205114 165 ETAARTELAASLPADLVELYERQRARY-GIGAALLTRRVTGGSGVELTSTDLDAVRAAapDDVVICPDSSCILVRTNE 241
Cdd:COG1579   161 LEAEREELAAKIPPELLALYERIRKRKnGLAVVPVEGGACGGCFMELPPQELNEIRAA--DEIVRCPNCGRILYREEE 236
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 6-190 2.02e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.48  E-value: 2.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   6 EDQLALLTlQERDNHITQLNHARKNIAE-QAELAEVTASLREFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIAKDKE 84
Cdd:COG1196   238 EAELEELE-AELEELEAELEELEAELAElEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114  85 REAGAasAKDLQALEAELASLATRKSNLEDIELVVMQSIEDAEVAVADVLVERDAVEARRAALAQAVSTREAEIDAELAA 164
Cdd:COG1196   317 RLEEL--EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                         170       180
                  ....*....|....*....|....*.
gi 1398205114 165 ETAARTELAASLPADLVELYERQRAR 190
Cdd:COG1196   395 AAELAAQLEELEEAEEALLERLERLE 420
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 6-228 6.62e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.77  E-value: 6.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   6 EDQLALLTLQERDNHITQLNHARKNIAEQAELAEVTASLREFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIAKDKER 85
Cdd:COG1196   308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114  86 EagAASAKDLQALEAELASLATRKSNLEDIELVVMQSIEDAEVAVADVLVERDAVEARRAALAQAVSTREAEIDAELA-- 163
Cdd:COG1196   388 L--LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEll 465

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1398205114 164 AETAARTELAASLPADLVELYERQRARYGIGAALLTRRVTGGSGVELTSTDLDAVRAAAPDDVVI 228
Cdd:COG1196   466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 29-201 1.77e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 1.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114  29 KNIAEQAELAEVTASL---REFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIAKdkEREAGAASAKDLQALEAELASL 105
Cdd:COG1196   216 RELKEELKELEAELLLlklRELEAELEELEAELEELEAELEELEAELAELEAELEE--LRLELEELELELEEAQAEEYEL 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114 106 ATRKSNLEDIELVVMQSIEDAEVAVADVLVERDAVEARRAALAQAVSTREAEID---AELAAETAARTELAASLPADLVE 182
Cdd:COG1196   294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEeaeEELEEAEAELAEAEEALLEAEAE 373

                         170
                  ....*....|....*....
gi 1398205114 183 LYERQRARYGIGAALLTRR 201
Cdd:COG1196   374 LAEAEEELEELAEELLEAL 392
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 6-172 3.08e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 3.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114    6 EDQLALLTLQERDNHITQLNHARKNIAEQAELAEVTASLREFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIA--KDK 83
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnlERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   84 EREAGAASAKDLQALEAELASLATRKSNLEDIElvvmQSIEDAEVAVADVLVERDAVEARRAALAQAVSTREAEIDAELA 163
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELK----EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393


                   ....*....
gi 1398205114  164 AETAARTEL 172
Cdd:TIGR02168  394 QIASLNNEI 402
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
13-174 3.13e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 3.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   13 TLQERDNHITQLNHARKNIAEQAELAEVTASLREfSQSLIAAQGVLEDAKIELARIEDDVRVVDERIAKDKEREAGA--- 89
Cdd:COG4913    253 LLEPIRELAERYAAARERLAELEYLRAALRLWFA-QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELeaq 331

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   90 ---ASAKDLQALEAELASLATRKSNLEDIELVVMQSIEDAEVAVADvlvERDAVEARRAALAQAVSTREAEIDAELAAET 166
Cdd:COG4913    332 irgNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPA---SAEEFAALRAEAAALLEALEEELEALEEALA 408


                   ....*...
gi 1398205114  167 AARTELAA 174
Cdd:COG4913    409 EAEAALRD 416
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
10-183 5.42e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 5.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   10 ALLTLQERDNHITQLNHARKNIAEQ-----AELAEVTASLREFSQSLIAAQGV-LEDAKIELARIEDDVRVVDERIAKDK 83
Cdd:COG4913    286 AQRRLELLEAELEELRAELARLEAElerleARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERRRARLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   84 E--REAGAASAKDLQALEAELASLATRKSNLEDIELVVMQSIEDAEVAVADVLVERDAVEARRAALAQAVSTreaeIDAE 161
Cdd:COG4913    366 AllAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN----IPAR 441

                          170       180
                   ....*....|....*....|..
gi 1398205114  162 LAaetAARTELAASLPADLVEL 183
Cdd:COG4913    442 LL---ALRDALAEALGLDEAEL 460
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
31-191 8.64e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.28  E-value: 8.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   31 IAEQAELAEVTASLREFSQSLIAAQGVLEDAKIELARIED------DVRVVDERIA-KDKEREAGAASAKDLQALEAELA 103
Cdd:COG4913    616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeiDVASAEREIAeLEAELERLDASSDDLAALEEQLE 695

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114  104 SLATRKSNLEDIELVVMQSIEDAEVAVADVLVERDAVEARRAALAQavstrEAEIDAELAAETAARTELAASLPADLVEL 183
Cdd:COG4913    696 ELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAED-----LARLELRALLEERFAAALGDAVERELREN 770


                   ....*...
gi 1398205114  184 YERQRARY 191
Cdd:COG4913    771 LEERIDAL 778
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
19-197 1.29e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.90  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   19 NHITQLNHARKNIAEQAELAEVTASLREFSQSLIAAQGVLEDAKIELARieddVRVVDERIAKDKEREAGAASAKDLQAL 98
Cdd:COG4913    232 EHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAA----LRLWFAQRRLELLEAELEELRAELARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   99 EAELASLATRKSNLEDIELVVMQS--------IEDAEVAVADVLVERDAVEARRAALAQAVSTREAEIDAELAAETAART 170
Cdd:COG4913    308 EAELERLEARLDALREELDELEAQirgnggdrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRA 387

                          170       180
                   ....*....|....*....|....*..
gi 1398205114  171 ELAASLPADLVELYERQRARYGIGAAL 197
Cdd:COG4913    388 EAAALLEALEEELEALEEALAEAEAAL 414
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 6-190 1.36e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.53  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   6 EDQLALLTLQERDNHITQLNHARKNIAEQAELAEVTASLREFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIAKDKER 85
Cdd:COG1196   357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114  86 EAgaASAKDLQALEAELASLATRKSNLEDIELVVMQSIEDAEVAVADVLVERDAVEARRAALAQAVSTREA--------- 156
Cdd:COG1196   437 EE--EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGflegvkaal 514

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1398205114 157 --------------EIDAELAAETAARTELAASLPADLVELYERQRAR 190
Cdd:COG1196   515 llaglrglagavavLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
44-190 6.03e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 37.59  E-value: 6.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   44 LREFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIAKDKEREAGAASAKDLQALEAELASLATRKSNLE--DIELVVMQ 121
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDasSDDLAALE 691

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114  122 S-IEDAEVAVADVLVERDAVEARRAALAQAVSTREAEIDAELAAETAARTELAASLPADLVELYERQRAR 190
Cdd:COG4913    692 EqLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD 761
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 6-189 6.83e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 37.35  E-value: 6.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114    6 EDQLALLTLQERDNHITQLNHARKNIAEQAELAEVTASLREFSQSLIAAQGVLEDAKIELARIEDDVRVVDERIAKDKER 85
Cdd:TIGR02169  208 EKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1398205114   86 EAgaasakdlQALEAELASLATRKSNLEDIELVVMQSIEDAEVAVADVLVERDAVEARRAALAQAVSTREAEIDAeLAAE 165
Cdd:TIGR02169  288 EQ--------LRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDK-LTEE 358

                          170       180
                   ....*....|....*....|....
gi 1398205114  166 TAARTELAASLPADLVELYERQRA 189
Cdd:TIGR02169  359 YAELKEELEDLRAELEEVDKEFAE 382
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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