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Conserved domains on  [gi|1422354951|ref|WP_111935927|]
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ABC transporter ATP-binding protein [Paraburkholderia bryophila]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11438412)

ABC transporter ATP-binding protein is part of a complex involved in the transport of a wide variety of different compounds, including sugars, ions, peptides, and drugs; similar to ATPase component of ABC-type multidrug transport systems

CATH:  3.40.50.300
Gene Ontology:  GO:0140359|GO:0016887|GO:0005524
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
8-225 1.65e-82

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


:

Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 248.83  E-value: 1.65e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQ 87
Cdd:COG1131     1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRRIGYVPQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepelllldepTA 165
Cdd:COG1131    81 EPALYPDLTVRENLRFFARLYGLPRKEAREriDELLELFGLTDAADRKVGTLSGGMKQRlglalallhdpellildepTS 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 166 GVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:COG1131   161 GLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERlCDRVAIIDKGRIVADGTPDELKAR 221
 
Name Accession Description Interval E-value
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
8-225 1.65e-82

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 248.83  E-value: 1.65e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQ 87
Cdd:COG1131     1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRRIGYVPQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepelllldepTA 165
Cdd:COG1131    81 EPALYPDLTVRENLRFFARLYGLPRKEAREriDELLELFGLTDAADRKVGTLSGGMKQRlglalallhdpellildepTS 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 166 GVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:COG1131   161 GLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERlCDRVAIIDKGRIVADGTPDELKAR 221
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
8-213 3.15e-60

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 189.53  E-value: 3.15e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQ 87
Cdd:cd03230     1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKRRIGYLPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDfvarlyevrrrrervdrmldelrlgsrakqlagsLSGGWKQRlalaaallqepelllldepTAGV 167
Cdd:cd03230    81 EPSLYENLTVRENLK----------------------------------LSGGMKQRlalaqallhdpellildepTSGL 126
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1422354951 168 DPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVL 213
Cdd:cd03230   127 DPESRREFWELLRELKKEGKTILLSSHILEEAERlCDRVAILNNGRI 173
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
15-299 4.41e-55

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 181.05  E-value: 4.41e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  15 KRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQRFTYWED 94
Cdd:TIGR01188   1 KVYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVVREPRKVRRSIGIVPQYASVDED 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  95 LTVRENLDFVARLY--EVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSAR 172
Cdd:TIGR01188  81 LTGRENLEMMGRLYglPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 173 REFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQG---EARDLIRQQALHTWAVSGANLVGLNDRLQGQ 248
Cdd:TIGR01188 161 RAIWDYIRALKEEGVTILLTTHYMEEADKlCDRIAIIDHGRIIAEGtpeELKRRLGKDTLESRPRDIQSLKVEVSMLIAE 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 249 PGVEQI------VAFGRSLHVSGGDPERLESSLNELKAEGAVIEKIDT---SLEHVFLHL 299
Cdd:TIGR01188 241 LGETGLgllavtVDSDRIKILVPDGDETVPEIVEAAIRNGIRIRSISTerpSLDDVFLKL 300
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
8-302 1.61e-50

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 169.22  E-value: 1.61e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQ 87
Cdd:PRK13537    8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQRVGVVPQ 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARLYEVRRRRERVD--RMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTA 165
Cdd:PRK13537   88 FDNLDPDFTVRENLLVFGRYFGLSAAAARALvpPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTT 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 166 GVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQ-ALHTWAVSGANLVGLND 243
Cdd:PRK13537  168 GLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERlCDRLCVIEEGRKIAEGAPHALIESEiGCDVIEIYGPDPVALRD 247
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 244 RLqgQPGVEQIVAFGRSLHVSGGDPERLESSLNElkAEGAVIEKIDTSLEHVFLHL----MKD 302
Cdd:PRK13537  248 EL--APLAERTEISGETLFCYVRDPEPLHARLKG--RAGLRYLHRPANLEDVFLRLtgreMQD 306
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3-230 1.32e-47

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 170.69  E-value: 1.32e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   3 ADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRV 82
Cdd:NF033858  262 DDEPAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGDIATRRRV 341
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 GYMTQRFTYWEDLTVRENLDFVARLYE--VRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepellll 160
Cdd:NF033858  342 GYMSQAFSLYGELTVRQNLELHARLFHlpAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRlslavavihkpellil 421
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 161 depTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQALHT 230
Cdd:NF033858  422 depTSGVDPVARDMFWRLLIELSREdGVTIFISTHFMNEAERCDRISLMHAGRVLASDTPAALVAARGAAT 492
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
23-144 2.72e-26

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 101.19  E-value: 2.72e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREI-KRRVGYMTQRFTYWEDLTVRENL 101
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSlRKEIGYVFQDPQLFPRLTVRENL 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1422354951 102 DFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAG----SLSGGWKQR 144
Cdd:pfam00005  81 RLGLLLKGLSKREKDAraEEALEKLGLGDLADRPVGerpgTLSGGQRQR 129
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
10-225 1.62e-24

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 103.67  E-value: 1.62e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  10 VHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS--REIKRRVGYMTQ 87
Cdd:NF033858    4 LEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARhrRAVCPRIAYMPQ 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 ---RFTYwEDLTVRENLDFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepellllde 162
Cdd:NF033858   84 glgKNLY-PTLSVFENLDFFGRLFGQDAAERRRriDELLRATGLAPFADRPAGKLSGGMKQKlglccalihdpdllilde 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 163 pTAGVDPSARREFWEELHRLAAR--GISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:NF033858  163 pTTGVDPLSRRQFWELIDRIRAErpGMSVLVATAYMEEAERFDWLVAMDAGRVLATGTPAELLAR 227
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
8-254 1.01e-19

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 87.87  E-value: 1.01e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMrMMCGLLTPDSGHGTCLGYDITKQSREIKRRVG-YMT 86
Cdd:NF000106   14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGA-LPAHV*GPDAGRRPWRF*TWCANRRALRRTIG*HRP 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRFTYWEDLTVRENLDFVARLY--EVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPT 164
Cdd:NF000106   93 VR*GRRESFSGRENLYMIGR*LdlSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPT 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 165 AGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQALHTWAVSGANLVGLnD 243
Cdd:NF000106  173 TGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQlAHELTVIDRGRVIADGKVDELKTKVGGRTLQIRPAHAAEL-D 251
                         250
                  ....*....|....
gi 1422354951 244 RLQG---QPGVEQI 254
Cdd:NF000106  252 RMVGaiaQAGLDGI 265
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
16-201 1.58e-12

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 64.95  E-value: 1.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  16 RFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgTClgyditkqSREIKRRVGYMTQRFTYWEDL 95
Cdd:NF040873    1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSG--TV--------RRAGGARVAYVPQRSEVPDSL 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  96 --TVRE--NLDFVARL----YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGV 167
Cdd:NF040873   71 plTVRDlvAMGRWARRglwrRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGL 150
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1422354951 168 DPSARREFWEELHRLAARGISVLVSTHYMDEAER 201
Cdd:NF040873  151 DAESRERIIALLAEEHARGATVVVVTHDLELVRR 184
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
32-62 2.99e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 40.43  E-value: 2.99e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1422354951   32 RGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGG 31
GguA NF040905
sugar ABC transporter ATP-binding protein;
15-55 6.84e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 37.85  E-value: 6.84e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1422354951  15 KRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCG 55
Cdd:NF040905    9 KTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG 49
 
Name Accession Description Interval E-value
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
8-225 1.65e-82

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 248.83  E-value: 1.65e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQ 87
Cdd:COG1131     1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRRIGYVPQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepelllldepTA 165
Cdd:COG1131    81 EPALYPDLTVRENLRFFARLYGLPRKEAREriDELLELFGLTDAADRKVGTLSGGMKQRlglalallhdpellildepTS 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 166 GVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:COG1131   161 GLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERlCDRVAIIDKGRIVADGTPDELKAR 221
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
8-213 3.15e-60

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 189.53  E-value: 3.15e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQ 87
Cdd:cd03230     1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKRRIGYLPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDfvarlyevrrrrervdrmldelrlgsrakqlagsLSGGWKQRlalaaallqepelllldepTAGV 167
Cdd:cd03230    81 EPSLYENLTVRENLK----------------------------------LSGGMKQRlalaqallhdpellildepTSGL 126
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1422354951 168 DPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVL 213
Cdd:cd03230   127 DPESRREFWELLRELKKEGKTILLSSHILEEAERlCDRVAILNNGRI 173
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
15-299 4.41e-55

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 181.05  E-value: 4.41e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  15 KRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQRFTYWED 94
Cdd:TIGR01188   1 KVYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVVREPRKVRRSIGIVPQYASVDED 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  95 LTVRENLDFVARLY--EVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSAR 172
Cdd:TIGR01188  81 LTGRENLEMMGRLYglPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 173 REFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQG---EARDLIRQQALHTWAVSGANLVGLNDRLQGQ 248
Cdd:TIGR01188 161 RAIWDYIRALKEEGVTILLTTHYMEEADKlCDRIAIIDHGRIIAEGtpeELKRRLGKDTLESRPRDIQSLKVEVSMLIAE 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 249 PGVEQI------VAFGRSLHVSGGDPERLESSLNELKAEGAVIEKIDT---SLEHVFLHL 299
Cdd:TIGR01188 241 LGETGLgllavtVDSDRIKILVPDGDETVPEIVEAAIRNGIRIRSISTerpSLDDVFLKL 300
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
8-222 2.94e-53

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 173.71  E-value: 2.94e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQ 87
Cdd:cd03265     1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREVRRRIGIVFQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARLY--EVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTA 165
Cdd:cd03265    81 DLSVDDELTGWENLYIHARLYgvPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTI 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951 166 GVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDL 222
Cdd:cd03265   161 GLDPQTRAHVWEYIEKLKEEfGMTILLTTHYMEEAEQlCDRVAIIDHGRIIAEGTPEEL 219
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
7-225 2.08e-51

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 169.65  E-value: 2.08e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMT 86
Cdd:COG4555     1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREARRQIGVLP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRFTYWEDLTVRENLDFVARLYEVRRRRERVD--RMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPT 164
Cdd:COG4555    81 DERGLYDRLTVRENIRYFAELYGLFDEELKKRieELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPT 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 165 AGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:COG4555   161 NGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEAlCDRVVILHKGKVVAQGSLDELREE 222
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
8-302 1.61e-50

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 169.22  E-value: 1.61e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQ 87
Cdd:PRK13537    8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQRVGVVPQ 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARLYEVRRRRERVD--RMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTA 165
Cdd:PRK13537   88 FDNLDPDFTVRENLLVFGRYFGLSAAAARALvpPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTT 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 166 GVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQ-ALHTWAVSGANLVGLND 243
Cdd:PRK13537  168 GLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERlCDRLCVIEEGRKIAEGAPHALIESEiGCDVIEIYGPDPVALRD 247
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 244 RLqgQPGVEQIVAFGRSLHVSGGDPERLESSLNElkAEGAVIEKIDTSLEHVFLHL----MKD 302
Cdd:PRK13537  248 EL--APLAERTEISGETLFCYVRDPEPLHARLKG--RAGLRYLHRPANLEDVFLRLtgreMQD 306
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
8-222 7.07e-48

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 159.59  E-value: 7.07e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGD--RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYM 85
Cdd:cd03263     1 LQIRNLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQSLGYC 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  86 TQRFTYWEDLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEP 163
Cdd:cd03263    81 PQFDALFDELTVREHLRFYARLkgLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEP 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 164 TAGVDPSARREFWEELHRLaARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDL 222
Cdd:cd03263   161 TSGLDPASRRAIWDLILEV-RKGRSIILTTHSMDEAEAlCDRIAIMSDGKLRCIGSPQEL 219
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3-230 1.32e-47

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 170.69  E-value: 1.32e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   3 ADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRV 82
Cdd:NF033858  262 DDEPAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGDIATRRRV 341
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 GYMTQRFTYWEDLTVRENLDFVARLYE--VRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepellll 160
Cdd:NF033858  342 GYMSQAFSLYGELTVRQNLELHARLFHlpAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRlslavavihkpellil 421
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 161 depTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQALHT 230
Cdd:NF033858  422 depTSGVDPVARDMFWRLLIELSREdGVTIFISTHFMNEAERCDRISLMHAGRVLASDTPAALVAARGAAT 492
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
8-286 8.05e-47

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 159.50  E-value: 8.05e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITkqsREIKRRVGYMTQ 87
Cdd:COG4152     2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLD---PEDRRRIGYLPE 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 -RFTYwEDLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepelllldept 164
Cdd:COG4152    79 eRGLY-PKMKVGEQLVYLARLkgLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQK-------------------- 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 165 A--------------------GVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLI 223
Cdd:COG4152   138 VqliaallhdpellildepfsGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEElCDRIVIINKGRKVLSGSVDEIR 217
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1422354951 224 RQQALHTWAVSGANLVGLndrLQGQPGVEQIVAFGRSLHV---SGGDPERLessLNELKAEGAVIE 286
Cdd:COG4152   218 RQFGRNTLRLEADGDAGW---LRALPGVTVVEEDGDGAELkleDGADAQEL---LRALLARGPVRE 277
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
1-299 4.63e-44

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 153.45  E-value: 4.63e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKR 80
Cdd:PRK13536   35 GSMSTVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLARA 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  81 RVGYMTQRFTYWEDLTVRENLDFVARLYEVRRRRERVD--RMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELL 158
Cdd:PRK13536  115 RIGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVipSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLL 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 159 LLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQ-ALHTWAVSGA 236
Cdd:PRK13536  195 ILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERlCDRLCVLEAGRKIAEGRPHALIDEHiGCQVIEIYGG 274
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 237 NLVGLndRLQGQPGVEQIVAFGRSLHVSGGDPERLESSLNELKaeGAVIEKIDTSLEHVFLHL 299
Cdd:PRK13536  275 DPHEL--SSLVKPYARRIEVSGETLFCYAPDPEQVRVQLRGRA--GLRLLQRPPNLEDVFLRL 333
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
8-217 2.42e-42

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 145.03  E-value: 2.42e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGeIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQ 87
Cdd:cd03264     1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRRIGYLPQ 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARLY--EVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTA 165
Cdd:cd03264    80 EFGVYPNFTVREFLDYIAWLKgiPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTA 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 166 GVDPSARREFWEELHRLAARGIsVLVSTHYM-DEAERCHKLAYISYGVLLAQG 217
Cdd:cd03264   160 GLDPEERIRFRNLLSELGEDRI-VILSTHIVeDVESLCNQVAVLNKGKLVFEG 211
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
8-217 2.55e-38

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 134.65  E-value: 2.55e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSrEIKRRVGYMTQ 87
Cdd:cd03268     1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNI-EALRRIGALIE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARLYEVRRRRERVdrMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGV 167
Cdd:cd03268    80 APGFYPNLTARENLRLLARLLGIRKKRIDE--VLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGL 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 168 DPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQG 217
Cdd:cd03268   158 DPDGIKELRELILSLRDQGITVLISSHLLSEIQKvADRIGIINKGKLIEEG 208
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
13-223 4.95e-38

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 134.59  E-value: 4.95e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  13 LNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQsrEIKRR----VGYMTQR 88
Cdd:cd03218     6 LSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKL--PMHKRarlgIGYLPQE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  89 FTYWEDLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAG 166
Cdd:cd03218    84 ASIFRKLTVEENILAVLEIrgLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPFAG 163
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951 167 VDPSARREFWEELHRLAARGISVLVSTHYMDEA-ERCHKlAYISY-GVLLAQGEARDLI 223
Cdd:cd03218   164 VDPIAVQDIQKIIKILKDRGIGVLITDHNVRETlSITDR-AYIIYeGKVLAEGTPEEIA 221
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
10-223 5.08e-37

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 132.08  E-value: 5.08e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  10 VHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSreIKRR----VGYM 85
Cdd:COG1137     6 AENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLP--MHKRarlgIGYL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  86 TQRFTYWEDLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepelllldep 163
Cdd:COG1137    84 PQEASIFRKLTVEDNILAVLELrkLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRR------------------- 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 164 T-------------------AGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKlAYISY-GVLLAQGEARDL 222
Cdd:COG1137   145 VeiaralatnpkfilldepfAGVDPIAVADIQKIIRHLKERGIGVLITDHNVRETLGiCDR-AYIISeGKVLAEGTPEEI 223

                  .
gi 1422354951 223 I 223
Cdd:COG1137   224 L 224
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
7-217 1.02e-36

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 130.57  E-value: 1.02e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDR----HVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRV 82
Cdd:cd03266     1 MITADALTKRFRDVkktvQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEARRRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 GYMTQRFTYWEDLTVRENLDFVARLY--EVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLL 160
Cdd:cd03266    81 GFVSDSTGLYDRLTARENLEYFAGLYglKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLL 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951 161 DEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQG 217
Cdd:cd03266   161 DEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERlCDRVVVLHRGRVVYEG 218
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
7-205 1.86e-36

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 129.52  E-value: 1.86e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMT 86
Cdd:COG4133     2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRRRLAYLG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRFTYWEDLTVRENLDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepelllldepTAG 166
Cdd:COG4133    82 HADGLKPELTVRENLRFWAALYGLRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRvalarlllspaplwlldepFTA 161
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1422354951 167 VDPSARREFWEELHRLAARGISVLVSTHYMDEAERCHKL 205
Cdd:COG4133   162 LDAAGVALLAELIAAHLARGGAVLLTTHQPLELAAARVL 200
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
13-223 1.52e-32

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 120.46  E-value: 1.52e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  13 LNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRR--VGYMTQRFT 90
Cdd:TIGR04406   7 LIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLPMHERARlgIGYLPQEAS 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  91 YWEDLTVRENLDFVARL---YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGV 167
Cdd:TIGR04406  87 IFRKLTVEENIMAVLEIrkdLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDEPFAGV 166
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951 168 DPSARREFWEELHRLAARGISVLVSTHYMDEAERCHKLAYISY-GVLLAQGEARDLI 223
Cdd:TIGR04406 167 DPIAVGDIKKIIKHLKERGIGVLITDHNVRETLDICDRAYIISdGKVLAEGTPAEIV 223
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
8-217 2.09e-32

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 119.31  E-value: 2.09e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHgtcLGYDITKQSREIKRRVGYMTQ 87
Cdd:cd03269     1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGE---VLFDGKPLDIAARNRIGYLPE 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTA 165
Cdd:cd03269    78 ERGLYPKMKVIDQLVYLAQLkgLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFS 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 166 GVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQG 217
Cdd:cd03269   158 GLDPVNVELLKDVIRELARAGKTVILSTHQMELVEElCDRVLLLNKGRAVLYG 210
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
8-202 3.22e-32

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 117.67  E-value: 3.22e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT---KQSREIKRRVGY 84
Cdd:cd03229     1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTdleDELPPLRRRIGM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  85 MTQRFTYWEDLTVRENLDFvarlyevrrrrervdrmldelrlgsrakqlagSLSGGWKQRLALAAALLQEPELLLLDEPT 164
Cdd:cd03229    81 VFQDFALFPHLTVLENIAL--------------------------------GLSGGQQQRVALARALAMDPDVLLLDEPT 128
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1422354951 165 AGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAERC 202
Cdd:cd03229   129 SALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARL 167
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
3-222 3.67e-30

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 113.92  E-value: 3.67e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   3 ADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR----EI 78
Cdd:COG1127     1 MSEPMIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEkelyEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  79 KRRVGYMTQR---FTyweDLTVRENLDFVARLYEVRRRRERV---DRMLDELRLGSRAKQLAGSLSGGWKQRlalaaall 152
Cdd:COG1127    81 RRRIGMLFQGgalFD---SLTVFENVAFPLREHTDLSEAEIRelvLEKLELVGLPGAADKMPSELSGGMRKRvalarala 157
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 153 qepelllldepTAGVDPSARREFWEELHRL-AARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDL 222
Cdd:COG1127   158 ldpeillydepTAGLDPITSAVIDELIRELrDELGLTSVVVTHDLDSAFAiADRVAVLADGKIIAEGTPEEL 229
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
8-226 6.75e-30

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 113.37  E-value: 6.75e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR----EIKRRVG 83
Cdd:cd03261     1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEaelyRLRRRMG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  84 YMTQRFTYWEDLTVRENLDFVARLYEVRRRRERVDRMLDELR---LGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLL 160
Cdd:cd03261    81 MLFQSGALFDSLTVFENVAFPLREHTRLSEEEIREIVLEKLEavgLRGAEDLYPAELSGGMKKRVALARALALDPELLLY 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951 161 DEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQ 226
Cdd:cd03261   161 DEPTAGLDPIASGVIDDLIRSLKKElGLTSIMVTHDLDTAFAiADRIAVLYDGKIVAEGTPEELRASD 228
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
11-217 7.89e-30

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 113.20  E-value: 7.89e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  11 HRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGY-MTQRF 89
Cdd:cd03267    25 SLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKFLRRIGVvFGQKT 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  90 TYWEDLTVRENLDFVARLYE--VRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGV 167
Cdd:cd03267   105 QLWWDLPVIDSFYLLAAIYDlpPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGL 184
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 168 DPSARREFWEELHRLAA-RGISVLVSTHYMDEAER-CHKLAYISYGVLLAQG 217
Cdd:cd03267   185 DVVAQENIRNFLKEYNReRGTTVLLTSHYMKDIEAlARRVLVIDKGRLLYDG 236
galliderm_ABC TIGR03740
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ...
8-218 2.60e-28

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.


Pssm-ID: 163452 [Multi-domain]  Cd Length: 223  Bit Score: 108.64  E-value: 2.60e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHgtcLGYDITKQSREIKRRVGYMTQ 87
Cdd:TIGR03740   1 LETKNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGE---IIFDGHPWTRKDLHKIGSLIE 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARLyeVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGV 167
Cdd:TIGR03740  78 SPPLYENLTARENLKVHTTL--LGLPDSRIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 168 DPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGE 218
Cdd:TIGR03740 156 DPIGIQELRELIRSFPEQGITVILSSHILSEVQQlADHIGIISEGVLGYQGK 207
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
7-249 2.68e-28

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 109.36  E-value: 2.68e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYM 85
Cdd:COG1120     1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSrRELARRIAYV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  86 TQRFTYWEDLTVRenlDFVA--RL-YEVRRRRERV------DRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepe 156
Cdd:COG1120    81 PQEPPAPFGLTVR---ELVAlgRYpHLGLFGRPSAedreavEEALERTGLEHLADRPVDELSGGERQRvliaralaqepp 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 157 lllldepTAGVDPSARREFWEELHRLAA-RGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQALHtwAVS 234
Cdd:COG1120   158 lllldepTSHLDLAHQLEVLELLRRLAReRGRTVVMVLHDLNLAARyADRLVLLKDGRIVAQGPPEEVLTPELLE--EVY 235
                         250
                  ....*....|....*
gi 1422354951 235 GANLVGLNDRLQGQP 249
Cdd:COG1120   236 GVEARVIEDPVTGRP 250
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
18-228 3.37e-28

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 108.57  E-value: 3.37e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMtqrFTYWED-- 94
Cdd:COG1122    12 GGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNlRELRRKVGLV---FQNPDDql 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  95 --LTVRENLDF------------VARLyevrrrrervDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepellll 160
Cdd:COG1122    89 faPTVEEDVAFgpenlglpreeiRERV----------EEALELVGLEHLADRPPHELSGGQKQRvaiagvlamepevlvl 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951 161 DEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQAL 228
Cdd:COG1122   159 DEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAElADRVIVLDDGRIVADGTPREVFSDYEL 227
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
3-229 4.10e-28

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 108.64  E-value: 4.10e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   3 ADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQsreiKRRV 82
Cdd:COG1121     2 MMMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRA----RRRI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 GYMTQRFTYWED--LTVRenlDFVA--RLYEVRRRRERV-------DRMLDELRLGSRAKQLAGSLSGGWKQRlalaaal 151
Cdd:COG1121    78 GYVPQRAEVDWDfpITVR---DVVLmgRYGRRGLFRRPSradreavDEALERVGLEDLADRPIGELSGGQQQRvllaral 154
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951 152 lqepelllldepTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVlLAQGEARDLIRQQALH 229
Cdd:COG1121   155 aqdpdlllldepFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREyFDRVLLLNRGL-VAHGPPEEVLTPENLS 232
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
7-144 7.17e-27

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 107.88  E-value: 7.17e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREiKRRVGYMT 86
Cdd:COG3842     5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPE-KRNVGMVF 83
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951  87 QRFTYWEDLTVRENLDF---------------VARlyevrrrrervdrMLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:COG3842    84 QDYALFPHLTVAENVAFglrmrgvpkaeirarVAE-------------LLELVGLEGLADRYPHQLSGGQQQR 143
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
8-144 2.08e-26

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 103.37  E-value: 2.08e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREiKRRVGYMTQ 87
Cdd:cd03259     1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPE-RRNIGMVFQ 79
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951  88 RFTYWEDLTVRENLDF--VARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:cd03259    80 DYALFPHLTVAENIAFglKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQR 138
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
23-144 2.72e-26

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 101.19  E-value: 2.72e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREI-KRRVGYMTQRFTYWEDLTVRENL 101
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSlRKEIGYVFQDPQLFPRLTVRENL 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1422354951 102 DFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAG----SLSGGWKQR 144
Cdd:pfam00005  81 RLGLLLKGLSKREKDAraEEALEKLGLGDLADRPVGerpgTLSGGQRQR 129
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
8-213 5.27e-26

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 102.57  E-value: 5.27e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGD----RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK-----QSREI 78
Cdd:cd03255     1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKlsekeLAAFR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  79 KRRVGYMTQRFTYWEDLTVRENLDFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPE 156
Cdd:cd03255    81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERREraEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951 157 LLLLDEPTAGVDPSARREFWEELHRLAA-RGISVLVSTHYMDEAERCHKLAYISYGVL 213
Cdd:cd03255   161 IILADEPTGNLDSETGKEVMELLRELNKeAGTTIVVVTHDPELAEYADRIIELRDGKI 218
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
18-218 7.40e-26

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 101.77  E-value: 7.40e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYM-----TQRFTy 91
Cdd:cd03225    12 GARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSlKELRRKVGLVfqnpdDQFFG- 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  92 wedLTVRENLDFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDP 169
Cdd:cd03225    91 ---PTVEEEVAFGLENLGLPEEEIEErvEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDP 167
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1422354951 170 SARREFWEELHRLAARGISVLVSTHYMDEAerchkLAYISYGVLLAQGE 218
Cdd:cd03225   168 AGRRELLELLKKLKAEGKTIIIVTHDLDLL-----LELADRVIVLEDGK 211
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
7-225 9.39e-26

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 102.27  E-value: 9.39e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDR----HVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS----REI 78
Cdd:cd03258     1 MIELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSgkelRKA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  79 KRRVGYMTQRFTYWEDLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPE 156
Cdd:cd03258    81 RRRIGMIFQHFNLLSSRTVFENVALPLEIagVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPK 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 157 LLLLDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:cd03258   161 VLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRiCDRVAVMEKGEVVEEGTVEEVFAN 231
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
8-224 1.56e-25

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 101.74  E-value: 1.56e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT-KQSREIKRR-VGYM 85
Cdd:cd03219     1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITgLPPHEIARLgIGRT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  86 TQRFTYWEDLTVRENLDFVARLYEVRRRRERVDR------------MLDELRLGSRAKQLAGSLSGGWKQRlalaaallq 153
Cdd:cd03219    81 FQIPRLFPELTVLENVMVAAQARTGSGLLLARARreereareraeeLLERVGLADLADRPAGELSYGQQRRleiaralat 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 154 epelllldePTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIR 224
Cdd:cd03219   161 dpklllldePAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSlADRVTVLDQGRVIAEGTPDEVRN 232
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
11-108 8.75e-25

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 101.70  E-value: 8.75e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  11 HRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGY-MTQRF 89
Cdd:COG4586    26 GLFRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYVPFKRRKEFARRIGVvFGQRS 105
                          90
                  ....*....|....*....
gi 1422354951  90 TYWEDLTVRENLDFVARLY 108
Cdd:COG4586   106 QLWWDLPAIDSFRLLKAIY 124
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
10-225 1.62e-24

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 103.67  E-value: 1.62e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  10 VHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS--REIKRRVGYMTQ 87
Cdd:NF033858    4 LEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARhrRAVCPRIAYMPQ 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 ---RFTYwEDLTVRENLDFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepellllde 162
Cdd:NF033858   84 glgKNLY-PTLSVFENLDFFGRLFGQDAAERRRriDELLRATGLAPFADRPAGKLSGGMKQKlglccalihdpdllilde 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 163 pTAGVDPSARREFWEELHRLAAR--GISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:NF033858  163 pTTGVDPLSRRQFWELIDRIRAErpGMSVLVATAYMEEAERFDWLVAMDAGRVLATGTPAELLAR 227
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
10-211 2.01e-24

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 96.55  E-value: 2.01e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  10 VHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK-QSREIKRRVGYMTQr 88
Cdd:cd00267     2 IENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKlPLEELRRRIGYVPQ- 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  89 ftywedltvrenldfvarlyevrrrrervdrmldelrlgsrakqlagsLSGGWKQRLALAAALLQEPELLLLDEPTAGVD 168
Cdd:cd00267    81 ------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSGLD 112
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1422354951 169 PSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYG 211
Cdd:cd00267   113 PASRERLLELLRELAEEGRTVIIVTHDPELAELaADRVIVLKDG 156
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
8-199 2.04e-24

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 97.99  E-value: 2.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT---KQSREIKRRVGY 84
Cdd:cd03262     1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTddkKNINELRQKVGM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  85 MTQRFTYWEDLTVRENLDF---VARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLD 161
Cdd:cd03262    81 VFQQFNLFPHLTVLENITLapiKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1422354951 162 EPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEA 199
Cdd:cd03262   161 EPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFA 198
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
7-217 2.09e-24

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 98.96  E-value: 2.09e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRR-VGY 84
Cdd:COG0411     4 LLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPpHRIARLgIAR 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  85 MTQRFTYWEDLTVRENLDfVARLYEVRRRRERVDR------------------MLDELRLGSRAKQLAGSLSGGWKQRla 146
Cdd:COG0411    84 TFQNPRLFPELTVLENVL-VAAHARLGRGLLAALLrlprarreereareraeeLLERVGLADRADEPAGNLSYGQQRRle 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 147 laaallqepelllldePTAGVDPSARREFWEELHRLAA-RGISVLVSTHYMDEAER-CHKLAYISYGVLLAQG 217
Cdd:COG0411   163 iaralatepklllldePAAGLNPEETEELAELIRRLRDeRGITILLIEHDMDLVMGlADRIVVLDFGRVIAEG 235
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
8-222 4.38e-24

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 97.50  E-value: 4.38e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQ-SREIKRR-VGYM 85
Cdd:cd03224     1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLpPHERARAgIGYV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  86 TQR---FTyweDLTVRENLDFVARLYEVRRRRERVDRMLDEL-RLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLD 161
Cdd:cd03224    81 PEGrriFP---ELTVEENLLLGAYARRRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLD 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 162 EPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEA-ERCHKLAYISYGVLLAQGEARDL 222
Cdd:cd03224   158 EPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFAlEIADRAYVLERGRVVLEGTAAEL 219
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
8-269 9.71e-24

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 99.07  E-value: 9.71e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG----HGTCLgyDITKQSREikRRVG 83
Cdd:COG1118     3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGrivlNGRDL--FTNLPPRE--RRVG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  84 YMTQRFTYWEDLTVRENLDFV--ARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepelllld 161
Cdd:COG1118    79 FVFQHYALFPHMTVAENIAFGlrVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQR----------------- 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 162 epTA-----GVDP---------SA-----RREFWEELHRL--AARGISVLVsTHYMDEA-ERCHKLAYISYGVLLAQGEA 219
Cdd:COG1118   142 --VAlaralAVEPevllldepfGAldakvRKELRRWLRRLhdELGGTTVFV-THDQEEAlELADRVVVMNQGRIEQVGTP 218
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1422354951 220 RDLIRQQAlhTWAVsgANLVGLNDRLQGQPGVEQIVAFGRSLHVSGGDPE 269
Cdd:COG1118   219 DEVYDRPA--TPFV--ARFLGCVNVLRGRVIGGQLEADGLTLPVAEPLPD 264
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
9-217 1.33e-23

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 94.81  E-value: 1.33e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   9 DVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMTQ 87
Cdd:cd03214     1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSpKELARKIAYVPQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 rftywedltvrenldfvarlyevrrrrervdrMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepelllldepTAGV 167
Cdd:cd03214    81 --------------------------------ALELLGLAHLADRPFNELSGGERQRvllaralaqeppillldepTSHL 128
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 168 DPSARREFWEELHRLAA-RGISVLVSTHYMDEAER-CHKLAYISYGVLLAQG 217
Cdd:cd03214   129 DIAHQIELLELLRRLAReRGKTVVMVLHDLNLAARyADRVILLKDGRIVAQG 180
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
8-222 3.54e-23

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 94.94  E-value: 3.54e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLL-----TPDSGHGTCLGYDITKQSR---EIK 79
Cdd:cd03260     1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNdlipgAPDEGEVLLDGKDIYDLDVdvlELR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  80 RRVGYMTQR---FtyweDLTVRENLDFVARLYEVRRRRERVDRMLDELR---LGSRAK--QLAGSLSGGWKQRLALAAAL 151
Cdd:cd03260    81 RRVGMVFQKpnpF----PGSIYDNVAYGLRLHGIKLKEELDERVEEALRkaaLWDEVKdrLHALGLSGGQQQRLCLARAL 156
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 152 LQEPELLLLDEPTAGVDPSARREFWEELHRLAARgISVLVSTHYMDEAERC-HKLAYISYGVLLAQGEARDL 222
Cdd:cd03260   157 ANEPEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVaDRTAFLLNGRLVEFGPTEQI 227
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
3-225 3.57e-23

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 99.21  E-value: 3.57e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   3 ADDLLIDVHRLNKRF-----GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-- 75
Cdd:COG1123   256 AAEPLLEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSrr 335
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  76 --REIKRRVGYMTQrftyweD--------LTVRENLDFVARLYEVRRRRERV---DRMLDELRLGSRAKQ-LAGSLSGGW 141
Cdd:COG1123   336 slRELRRRVQMVFQ------DpysslnprMTVGDIIAEPLRLHGLLSRAERRervAELLERVGLPPDLADrYPHELSGGQ 409
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 142 KQRlalaaallqepelllldepTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEA 219
Cdd:COG1123   410 RQRvaiaralalepkllildepTSALDVSVQAQILNLLRDLQRElGLTYLFISHDLAVVRYiADRVAVMYDGRIVEDGPT 489

                  ....*.
gi 1422354951 220 RDLIRQ 225
Cdd:COG1123   490 EEVFAN 495
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
10-194 3.60e-23

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 94.91  E-value: 3.60e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  10 VHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSReikrRVGYMTQRF 89
Cdd:cd03235     2 VEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERK----RIGYVPQRR 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  90 TY-WE-DLTVRenlDFVA-RLYEVRRRRERV--------DRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELL 158
Cdd:cd03235    78 SIdRDfPISVR---DVVLmGLYGHKGLFRRLskadkakvDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLL 154
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1422354951 159 LLDEPTAGVDPSARREFWEELHRLAARGISVLVSTH 194
Cdd:cd03235   155 LLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTH 190
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
7-218 2.05e-22

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 93.12  E-value: 2.05e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRR-VGY 84
Cdd:COG0410     3 MLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPpHRIARLgIGY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  85 MTQR---FTyweDLTVRENLDFVARLYEVRRRRERVDRMLDEL--RLGSRAKQLAGSLSGGWKQrlalaaallqepelll 159
Cdd:COG0410    83 VPEGrriFP---SLTVEENLLLGAYARRDRAEVRADLERVYELfpRLKERRRQRAGTLSGGEQQmlaigralmsrpklll 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951 160 LDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAerchkLAYISYGVLLAQGE 218
Cdd:COG0410   160 LDEPSLGLAPLIVEEIFEIIRRLNREGVTILLVEQNARFA-----LEIADRAYVLERGR 213
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
7-216 2.07e-22

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 93.18  E-value: 2.07e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGD----RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REI--- 78
Cdd:COG1136     4 LLELRNLTKSYGTgegeVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSeRELarl 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  79 -KRRVGYMTQRFTYWEDLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqep 155
Cdd:COG1136    84 rRRHIGFVFQFFNLLPELTALENVALPLLLagVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRvaiaralvnrp 163
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 156 ellllDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAERCHKLAYISYGVLLAQ 216
Cdd:COG1136   164 klilaDEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHDPELAARADRVIRLRDGRIVSD 225
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
8-213 2.77e-22

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 92.19  E-value: 2.77e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMT 86
Cdd:COG4619     1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPpPEWRRQVAYVP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRFTYWEDlTVRENLDFVARLYEVRRRRERVDRMLDELRLGSRA-KQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTA 165
Cdd:COG4619    81 QEPALWGG-TVRDNLPFPFQLRERKFDRERALELLERLGLPPDIlDKPVERLSGGERQRLALIRALLLQPDVLLLDEPTS 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1422354951 166 GVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVL 213
Cdd:COG4619   160 ALDPENTRRVEELLREYLAEeGRAVLWVSHDPEQIERvADRVLTLEAGRL 209
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
8-204 6.46e-22

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 91.65  E-value: 6.46e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRF-GDRHVVKDLSMQVRRGEiFGFL-GPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE----IKRR 81
Cdd:COG2884     2 IRFENVSKRYpGGREALSDVSLEIEKGE-FVFLtGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRReipyLRRR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  82 VGYMTQRFTYWEDLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepelll 159
Cdd:COG2884    81 IGVVFQDFRLLPDRTVYENVALPLRVtgKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRvaiaralvnrpelll 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1422354951 160 LDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAERCHK 204
Cdd:COG2884   161 ADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRMPK 205
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
7-227 1.02e-21

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 94.97  E-value: 1.02e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRF--GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLtPDSGH--GTCL--GYDITKQSREIK- 79
Cdd:COG1123     4 LLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLL-PHGGRisGEVLldGRDLLELSEALRg 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  80 RRVGYMTQRF-TYWEDLTVRENLDFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPE 156
Cdd:COG1123    83 RRIGMVFQDPmTQLNPVTVGDQIAEALENLGLSRAEARArvLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPD 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 157 LLLLDEPTAGVDPSARREFWEELHRLAA-RGISVLVSTHYMDE-AERCHKLAYISYGVLLAQGEARDLIRQQA 227
Cdd:COG1123   163 LLIADEPTTALDVTTQAEILDLLRELQReRGTTVLLITHDLGVvAEIADRVVVMDDGRIVEDGPPEEILAAPQ 235
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
8-144 1.50e-21

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 90.76  E-value: 1.50e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREiKRRVGYMTQ 87
Cdd:cd03300     1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPH-KRPVNTVFQ 79
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951  88 RFTYWEDLTVRENLDFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:cd03300    80 NYALFPHLTVFENIAFGLRLKKLPKAEIKErvAEALDLVQLEGYANRKPSQLSGGQQQR 138
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
8-227 3.22e-21

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 90.05  E-value: 3.22e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRH-VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR-EIKRRVGYM 85
Cdd:cd03295     1 IEFENVTKRYGGGKkAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPvELRRKIGYV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  86 TQRFTYWEDLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSR--AKQLAGSLSGGWKQRLALAAALLQEPELLLLD 161
Cdd:cd03295    81 IQQIGLFPHMTVEENIALVPKLlkWPKEKIRERADELLALVGLDPAefADRYPHELSGGQQQRVGVARALAADPPLLLMD 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951 162 EPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQA 227
Cdd:cd03295   161 EPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRlADRIAIMKNGEIVQVGTPDEILRSPA 228
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
2-222 4.13e-21

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 93.92  E-value: 4.13e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951    2 NADDLLiDVHRLNKRFG--DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIK 79
Cdd:TIGR01257 1933 NKTDIL-RLNELTKVYSgtSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVH 2011
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   80 RRVGYMTQRFTYWEDLTVRENLDFVARLYEVRRRRERVDR--MLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPEL 157
Cdd:TIGR01257 2012 QNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVAnwSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPL 2091
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1422354951  158 LLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDL 222
Cdd:TIGR01257 2092 VLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEAlCTRLAIMVKGAFQCLGTIQHL 2157
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
8-144 4.66e-21

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 91.67  E-value: 4.66e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH---GtclGYDITKQSREiKRRVGY 84
Cdd:COG3839     4 LELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEiliG---GRDVTDLPPK-DRNIAM 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951  85 MTQRFTYWEDLTVRENLDF---------------VARlyevrrrrervdrMLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:COG3839    80 VFQSYALYPHMTVYENIAFplklrkvpkaeidrrVRE-------------AAELLGLEDLLDRKPKQLSGGQRQR 141
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
12-217 5.66e-21

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 88.89  E-value: 5.66e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  12 RLNKRFGDRHVvkDLSMQVRrGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH----GTCLgyDITKQSREI---KRRVGY 84
Cdd:cd03297     5 DIEKRLPDFTL--KIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTivlnGTVL--FDSRKKINLppqQRKIGL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  85 MTQRFTYWEDLTVRENLDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPT 164
Cdd:cd03297    80 VFQQYALFPHLNVRENLAFGLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPF 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 165 AGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQG 217
Cdd:cd03297   160 SALDRALRLQLLPELKQIKKNlNIPVIFVTHDLSEAEYlADRIVVMEDGRLQYIG 214
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
20-295 6.35e-21

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 93.54  E-value: 6.35e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   20 RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQRFTYWEDLTVRE 99
Cdd:TIGR01257  943 RPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLDAVRQSLGMCPQHNILFHHLTVAE 1022
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  100 NLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREFWE 177
Cdd:TIGR01257 1023 HILFYAQLkgRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWD 1102
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  178 ELHRLAArGISVLVSTHYMDEAERC-HKLAYISYGVLLAQGEArdLIRQQALHTWAVsgANLVGLNDRLQGQPGVEQIVA 256
Cdd:TIGR01257 1103 LLLKYRS-GRTIIMSTHHMDEADLLgDRIAIISQGRLYCSGTP--LFLKNCFGTGFY--LTLVRKMKNIQSQRGGCEGTC 1177
                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1422354951  257 FGRSLHVSGGDPERLESSLNELKAEGAVIEKIDTSLEHV 295
Cdd:TIGR01257 1178 SCTSKGFSTRCPARVDEITPEQVLDGDVNELMDLVYHHV 1216
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
1-199 2.19e-20

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 88.22  E-value: 2.19e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNADDLLIDVHRLNKRF----GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR 76
Cdd:COG1116     1 MSAAAPALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  77 eikrRVGYMTQRFTY--WedLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaall 152
Cdd:COG1116    81 ----DRGVVFQEPALlpW--LTVLDNVALGLELrgVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRvaiarala 154
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1422354951 153 qepelllldeptAGVDPSARREFWEELHRL-AARGISVLVSTHYMDEA 199
Cdd:COG1116   155 ndpevllmdepfGALDALTRERLQDELLRLwQETGKTVLFVTHDVDEA 202
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
8-201 3.44e-20

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 87.24  E-value: 3.44e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGD-RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS----REIKRRV 82
Cdd:cd03256     1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKgkalRQLRRQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 GYMTQRFTYWEDLTVRENLdFVARL-----------YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAAL 151
Cdd:cd03256    81 GMIFQQFNLIERLSVLENV-LSGRLgrrstwrslfgLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARAL 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 152 LQEPELLLLDEPTAGVDPSARREFWEELHRLA-ARGISVLVSTHYMDEAER 201
Cdd:cd03256   160 MQQPKLILADEPVASLDPASSRQVMDLLKRINrEEGITVIVSLHQVDLARE 210
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
13-223 7.68e-20

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 86.49  E-value: 7.68e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  13 LNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT--KQSREIKRRVGYMTQRFT 90
Cdd:PRK10895    9 LAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISllPLHARARRGIGYLPQEAS 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  91 YWEDLTVRENLDFVARL---YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGV 167
Cdd:PRK10895   89 IFRRLSVYDNLMAVLQIrddLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGV 168
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951 168 DPSARREFWEELHRLAARGISVLVSTHYMDEA-ERCHKLAYISYGVLLAQGEARDLI 223
Cdd:PRK10895  169 DPISVIDIKRIIEHLRDSGLGVLITDHNVRETlAVCERAYIVSQGHLIAHGTPTEIL 225
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
7-224 9.22e-20

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 86.40  E-value: 9.22e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFG----DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT-KQSREIKRR 81
Cdd:COG1124     1 MLEVRNLSVSYGqggrRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTrRRRKAFRRR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  82 VGYMTQ--------RFTywedltVRENLDFVARLYEVRRRRERVDRMLDELRLGSR-AKQLAGSLSGGWKQRLALAAALL 152
Cdd:COG1124    81 VQMVFQdpyaslhpRHT------VDRILAEPLRIHGLPDREERIAELLEQVGLPPSfLDRYPHQLSGGQRQRVAIARALI 154
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1422354951 153 QEPELLLLDEPTAGVDPSARREFWEELHRL-AARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIR 224
Cdd:COG1124   155 LEPELLLLDEPTSALDVSVQAEILNLLKDLrEERGLTYLFVSHDLAVVAHlCDRVAVMQNGRIVEELTVADLLA 228
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
8-254 1.01e-19

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 87.87  E-value: 1.01e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMrMMCGLLTPDSGHGTCLGYDITKQSREIKRRVG-YMT 86
Cdd:NF000106   14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGA-LPAHV*GPDAGRRPWRF*TWCANRRALRRTIG*HRP 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRFTYWEDLTVRENLDFVARLY--EVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPT 164
Cdd:NF000106   93 VR*GRRESFSGRENLYMIGR*LdlSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPT 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 165 AGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQALHTWAVSGANLVGLnD 243
Cdd:NF000106  173 TGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQlAHELTVIDRGRVIADGKVDELKTKVGGRTLQIRPAHAAEL-D 251
                         250
                  ....*....|....
gi 1422354951 244 RLQG---QPGVEQI 254
Cdd:NF000106  252 RMVGaiaQAGLDGI 265
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
7-223 3.63e-19

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 84.37  E-value: 3.63e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT---KQSREIKRRVG 83
Cdd:PRK09493    1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNdpkVDERLIRQEAG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  84 YMTQRFTYWEDLTVRENLDF---VARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLL 160
Cdd:PRK09493   81 MVFQQFYLFPHLTALENVMFgplRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1422354951 161 DEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAERC-HKLAYISYGVLLAQGEARDLI 223
Cdd:PRK09493  161 DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVaSRLIFIDKGRIAEDGDPQVLI 224
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
8-268 9.74e-19

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 85.66  E-value: 9.74e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMT 86
Cdd:PRK09536    4 IDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSaRAASRRVASVP 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRFTYWEDLTVRENLDF-----VARLYEVRRRRERV-DRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLL 160
Cdd:PRK09536   84 QDTSLSFEFDVRQVVEMgrtphRSRFDTWTETDRAAvERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLL 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 161 DEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQALHTwAVSGANLV 239
Cdd:PRK09536  164 DEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDLAARyCDELVLLADGRVRAAGPPADVLTADTLRA-AFDARTAV 242
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1422354951 240 GlNDRLQGQPGVEQI-------VAFGRSLHVSG-GDP 268
Cdd:PRK09536  243 G-TDPATGAPTVTPLpdpdrteAAADTRVHVVGgGQP 278
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
8-199 1.14e-18

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 83.16  E-value: 1.14e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREiKRRVGYMTQ 87
Cdd:cd03296     3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQ-ERNVGFVFQ 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDF------VARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLD 161
Cdd:cd03296    82 HYALFRHMTVFDNVAFglrvkpRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLD 161
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1422354951 162 EPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEA 199
Cdd:cd03296   162 EPFGALDAKVRKELRRWLRRLHDElHVTTVFVTHDQEEA 200
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
8-199 1.70e-18

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 82.13  E-value: 1.70e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDR----HVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSReikrRVG 83
Cdd:cd03293     1 LEVRNVSKTYGGGggavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGP----DRG 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  84 YMTQRFTYWEDLTVREN--LDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLD 161
Cdd:cd03293    77 YVFQQDALLPWLTVLDNvaLGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLD 156
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1422354951 162 EPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEA 199
Cdd:cd03293   157 EPFSALDALTREQLQEELLDIWREtGKTVLLVTHDIDEA 195
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
7-225 3.12e-18

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 81.96  E-value: 3.12e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT---KQSREIKRRVG 83
Cdd:COG1126     1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTdskKDINKLRRKVG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  84 YMTQRFTYWEDLTVRENL-------------DFVARlyevrrrrerVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaa 150
Cdd:COG1126    81 MVFQQFNLFPHLTVLENVtlapikvkkmskaEAEER----------AMELLERVGLADKADAYPAQLSGGQQQRvaiara 150
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1422354951 151 llqepelllLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:COG1126   151 lamepkvmlFDEPTSALDPELVGEVLDVMRDLAKEGMTMVVVTHEMGFAREvADRVVFMDGGRIVEEGPPEEFFEN 226
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
5-144 4.93e-18

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 83.96  E-value: 4.93e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   5 DLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyditkqsrEIKR---- 80
Cdd:COG0488   313 KKVLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSG--------------TVKLgetv 378
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1422354951  81 RVGYMTQRFTYW-EDLTVRENLdfvaRLYEVRRRRERVDRMLDELRL-GSRAKQLAGSLSGGWKQR 144
Cdd:COG0488   379 KIGYFDQHQEELdPDKTVLDEL----RDGAPGGTEQEVRGYLGRFLFsGDDAFKPVGVLSGGEKAR 440
cbiO TIGR01166
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ...
18-199 2.10e-17

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130234 [Multi-domain]  Cd Length: 190  Bit Score: 78.62  E-value: 2.10e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG----HGTCLGYDiTKQSREIKRRVGYMTQR----- 88
Cdd:TIGR01166   3 GGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGavliDGEPLDYS-RKGLLERRQRVGLVFQDpddql 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  89 --FTYWEDLT----------------VRENLdfvarlyevrrrrervdRMLDELRLGSRAKQLagsLSGGWKQRLALAAA 150
Cdd:TIGR01166  82 faADVDQDVAfgplnlglseaeverrVREAL-----------------TAVGASGLRERPTHC---LSGGEKKRVAIAGA 141
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1422354951 151 LLQEPELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEA 199
Cdd:TIGR01166 142 VAMRPDVLLLDEPTAGLDPAGREQMLAILRRLRAEGMTVVISTHDVDLA 190
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
7-144 4.89e-17

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 78.32  E-value: 4.89e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRF----GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIK--- 79
Cdd:cd03257     1 LLEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRkir 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951  80 -RRVGYMTQ--------RFTYWEdlTVRENLDFVARLYEVRRRRERVDRMLDELRLGS-RAKQLAGSLSGGWKQR 144
Cdd:cd03257    81 rKEIQMVFQdpmsslnpRMTIGE--QIAEPLRIHGKLSKKEARKEAVLLLLVGVGLPEeVLNRYPHELSGGQRQR 153
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
18-226 5.56e-17

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 79.01  E-value: 5.56e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR--EIKRRVGYMTQRftywED- 94
Cdd:TIGR04520  13 SEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLDEENlwEIRKKVGMVFQN----PDn 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  95 ----LTVRENLDF------------VARLYEVrrrrervdrmLDELRLGSRAKQLAGSLSGGWKQRLALaaallqepell 158
Cdd:TIGR04520  89 qfvgATVEDDVAFglenlgvpreemRKRVDEA----------LKLVGMEDFRDREPHLLSGGQKQRVAI----------- 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 159 lldeptAGV-----------------DPSARREFWEELHRLAA-RGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEAR 220
Cdd:TIGR04520 148 ------AGVlamrpdiiildeatsmlDPKGRKEVLETIRKLNKeEGITVISITHDMEEAVLADRVIVMNKGKIVAEGTPR 221

                  ....*.
gi 1422354951 221 DLIRQQ 226
Cdd:TIGR04520 222 EIFSQV 227
COG4674 COG4674
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1-144 5.93e-17

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443710 [Multi-domain]  Cd Length: 250  Bit Score: 78.62  E-value: 5.93e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNAD---DLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR- 76
Cdd:COG4674     1 MSLDtmhGPILYVEDLTVSFDGFKALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGLDEh 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  77 EIKRR-VGYMTQRFTYWEDLTVRENLD------------FVARLyeVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQ 143
Cdd:COG4674    81 EIARLgIGRKFQKPTVFEELTVFENLElalkgdrgvfasLFARL--TAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQ 158

                  .
gi 1422354951 144 R 144
Cdd:COG4674   159 W 159
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
8-289 1.01e-16

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 79.35  E-value: 1.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRF----GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS----REIK 79
Cdd:COG1135     2 IELENLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSerelRAAR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  80 RRVGYMTQRFTYWEDLTVRENLDF---------------VARLyevrrrrervdrmLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:COG1135    82 RKIGMIFQHFNLLSSRTVAENVALpleiagvpkaeirkrVAEL-------------LELVGLSDKADAYPSQLSGGQKQR 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 145 lalaaallqepelllLDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQGE---- 218
Cdd:COG1135   149 vgiaralannpkvllCDEATSALDPETTRSILDLLKDINRElGLTIVLITHEMDVVRRiCDRVAVLENGRIVEQGPvldv 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 219 --------ARDLIRQ-----------QALHTWAVSGANL-VGLNDRLQGQP------------------GVEQI--VAFG 258
Cdd:COG1135   229 fanpqselTRRFLPTvlndelpeellARLREAAGGGRLVrLTFVGESADEPllselarrfgvdvnilsgGIEEIqgTPVG 308
                         330       340       350
                  ....*....|....*....|....*....|..
gi 1422354951 259 R-SLHVSgGDPERLESSLNELKAEGAVIEKID 289
Cdd:COG1135   309 RlIVELE-GDDAAIDAALAYLREQGVVVEVLG 339
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
10-144 1.06e-16

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 80.11  E-value: 1.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  10 VHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyDITKQSREikrRVGYMTQRF 89
Cdd:COG0488     1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSG-------EVSIPKGL---RIGYLPQEP 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  90 TYWEDLTVREN-----------LDFVARLYEVRRRRERVDRMLDEL-----RLG-----SRAKQLA-------------- 134
Cdd:COG0488    71 PLDDDLTVLDTvldgdaelralEAELEELEAKLAEPDEDLERLAELqeefeALGgweaeARAEEILsglgfpeedldrpv 150
                         170
                  ....*....|
gi 1422354951 135 GSLSGGWKQR 144
Cdd:COG0488   151 SELSGGWRRR 160
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
8-219 1.16e-16

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 77.75  E-value: 1.16e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDI-------TKQSREIKR 80
Cdd:COG4161     3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFdfsqkpsEKAIRLLRQ 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  81 RVGYMTQRFTYWEDLTVRENLD----FVARLyEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPE 156
Cdd:COG4161    83 KVGMVFQQYNLWPHLTVMENLIeapcKVLGL-SKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQ 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1422354951 157 LLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEA 219
Cdd:COG4161   162 VLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHEVEFARKvASQVVYMEKGRIIEQGDA 225
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
12-228 2.16e-16

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 78.62  E-value: 2.16e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  12 RLNKRFGDRHVvkDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH----GTCL-----GYDITKQsreiKRRV 82
Cdd:TIGR02142   4 RFSKRLGDFSL--DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEivlnGRTLfdsrkGIFLPPE----KRRI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 GYMTQRFTYWEDLTVRENLDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDE 162
Cdd:TIGR02142  78 GYVFQEARLFPHLSVRGNLRYGMKRARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDE 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951 163 PTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQAL 228
Cdd:TIGR02142 158 PLAALDDPRKYEILPYLERLHAEfGIPILYVSHSLQEVLRlADRVVVLEDGRVAAAGPIAEVWASPDL 225
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
8-144 3.70e-16

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 77.82  E-value: 3.70e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK-QSREikRRVGYMT 86
Cdd:PRK10851    3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRlHARD--RKVGFVF 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1422354951  87 QRFTYWEDLTVRENLDFVARLY------EVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:PRK10851   81 QHYALFRHMTVFDNIAFGLTVLprrerpNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQR 144
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-144 3.70e-16

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 78.07  E-value: 3.70e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREiKR 80
Cdd:PRK09452    8 PSSLSPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAE-NR 86
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1422354951  81 RVGYMTQRFTYWEDLTVRENLDFVARLYEVRRRRERVDRM--LDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:PRK09452   87 HVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMeaLRMVQLEEFAQRKPHQLSGGQQQR 152
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
10-108 3.93e-16

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 76.27  E-value: 3.93e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  10 VHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyditkqsrEIKRR-------- 81
Cdd:COG1134    29 LRRRRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSG--------------RVEVNgrvsalle 94
                          90       100
                  ....*....|....*....|....*....
gi 1422354951  82 --VGYMtqrftywEDLTVRENLDFVARLY 108
Cdd:COG1134    95 lgAGFH-------PELTGRENIYLNGRLL 116
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
7-144 4.22e-16

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 76.35  E-value: 4.22e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK-QSREIKRRVGYM 85
Cdd:PRK13548    2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADwSPAELARRRAVL 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951  86 TQRFTYWEDLTVREnldfVARL--YEVRRRRERVDRMLDELRLGSRAKQLAG----SLSGGWKQR 144
Cdd:PRK13548   82 PQHSSLSFPFTVEE----VVAMgrAPHGLSRAEDDALVAAALAQVDLAHLAGrdypQLSGGEQQR 142
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
8-144 6.01e-16

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 74.98  E-value: 6.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREiKRRVGYMTQ 87
Cdd:cd03301     1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPK-DRDIAMVFQ 79
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951  88 RFTYWEDLTVRENLDFVARLYEVRRRR-----ERVDRMLD-ELRLGSRAKQlagsLSGGWKQR 144
Cdd:cd03301    80 NYALYPHMTVYDNIAFGLKLRKVPKDEidervREVAELLQiEHLLDRKPKQ----LSGGQRQR 138
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
7-217 6.84e-16

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 76.21  E-value: 6.84e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGD--RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR-EIKRRVG 83
Cdd:PRK13635    5 IIRVEHISFRYPDaaTYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVwDVRRQVG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  84 YMTQ----RFTyweDLTVRENLDF------------VARLyevrrrrervDRMLDELRLGSRAKQLAGSLSGGWKQRLAL 147
Cdd:PRK13635   85 MVFQnpdnQFV---GATVQDDVAFglenigvpreemVERV----------DQALRQVGMEDFLNREPHRLSGGQKQRVAI 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 148 AAALLQEPELLLLDEPTAGVDPSARREFWEELHRL-AARGISVLVSTHYMDEAERCHKLAYISYGVLLAQG 217
Cdd:PRK13635  152 AGVLALQPDIIILDEATSMLDPRGRREVLETVRQLkEQKGITVLSITHDLDEAAQADRVIVMNKGEILEEG 222
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
8-219 1.43e-15

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 74.67  E-value: 1.43e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLG--YDIT-----KQSREIKR 80
Cdd:PRK11124    3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGnhFDFSktpsdKAIRELRR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  81 RVGYMTQRFTYWEDLTVRENLD----FVARLyEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPE 156
Cdd:PRK11124   83 NVGMVFQQYNLWPHLTVQQNLIeapcRVLGL-SKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQ 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1422354951 157 LLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEA 219
Cdd:PRK11124  162 VLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKtASRVVYMENGHIVEQGDA 225
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
15-227 1.54e-15

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 74.99  E-value: 1.54e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  15 KRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS----REIKR-RVGYMTQRF 89
Cdd:cd03294    32 KKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSrkelRELRRkKISMVFQSF 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  90 TYWEDLTVRENLDFVARLYEVRRRRERVDRM--LDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGV 167
Cdd:cd03294   112 ALLPHRTVLENVAFGLEVQGVPRAEREERAAeaLELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSAL 191
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 168 DPSARREFWEELHRLAA-RGISVLVSTHYMDEAERC-HKLAYISYGVLLAQGEARDLIRQQA 227
Cdd:cd03294   192 DPLIRREMQDELLRLQAeLQKTIVFITHDLDEALRLgDRIAIMKDGRLVQVGTPEEILTNPA 253
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
12-217 1.74e-15

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 73.68  E-value: 1.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  12 RLNK-RFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITkQSREIKRRVGYMTQRFT 90
Cdd:cd03298     2 RLDKiRFSYGEQPMHFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVT-AAPPADRPVSMLFQENN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  91 YWEDLTVRENLDF--VARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVD 168
Cdd:cd03298    81 LFAHLTVEQNVGLglSPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALD 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 169 PSARREFWE---ELHRlaARGISVLVSTHYMDEAERC-HKLAYISYGVLLAQG 217
Cdd:cd03298   161 PALRAEMLDlvlDLHA--ETKMTVLMVTHQPEDAKRLaQRVVFLDNGRIAAQG 211
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
7-220 1.85e-15

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 74.66  E-value: 1.85e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDS---GHGTCLGYDITKQ---SREIKR 80
Cdd:PRK09984    4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKsagSHIELLGRTVQREgrlARDIRK 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  81 ---RVGYMTQRFTYWEDLTVRENLdFVARL-----------YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLA 146
Cdd:PRK09984   84 sraNTGYIFQQFNLVNRLSVLENV-LIGALgstpfwrtcfsWFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVA 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1422354951 147 LAAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEAR 220
Cdd:PRK09984  163 IARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdGITVVVTLHQVDYALRyCERIVALRQGHVFYDGSSQ 238
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
11-108 2.25e-15

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 73.72  E-value: 2.25e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  11 HRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyditkqsrEIKRR--------- 81
Cdd:cd03220    26 LGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSG--------------TVTVRgrvssllgl 91
                          90       100
                  ....*....|....*....|....*...
gi 1422354951  82 -VGYMtqrftywEDLTVRENLDFVARLY 108
Cdd:cd03220    92 gGGFN-------PELTGRENIYLNGRLL 112
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
8-230 6.02e-15

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 73.12  E-value: 6.02e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMT 86
Cdd:PRK11231    3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSsRQLARRLALLP 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRFTYWEDLTVRE--------NLDFVARLyeVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELL 158
Cdd:PRK11231   83 QHHLTPEGITVRElvaygrspWLSLWGRL--SAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVV 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 159 LLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQALHT 230
Cdd:PRK11231  161 LLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRyCDHLVVLANGHVMAQGTPEEVMTPGLLRT 233
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
8-62 8.78e-15

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 70.54  E-value: 8.78e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:cd03216     1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSG 55
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
18-101 1.12e-14

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 70.49  E-value: 1.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK-QSREIKRRVGYMTQRFTYWEDlT 96
Cdd:cd03228    13 RPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDlDLESLRKNIAYVPQDPFLFSG-T 91

                  ....*
gi 1422354951  97 VRENL 101
Cdd:cd03228    92 IRENI 96
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
8-194 1.13e-14

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 71.67  E-value: 1.13e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRF-GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE----IKRRV 82
Cdd:cd03292     1 IEFINVTKTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRaipyLRRKI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 GYMTQRFTYWEDLTVRENLDFVARLYEVRRRRERVDRM--LDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLL 160
Cdd:cd03292    81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPaaLELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1422354951 161 DEPTAGVDPSARREFWEELHRLAARGISVLVSTH 194
Cdd:cd03292   161 DEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATH 194
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
10-194 2.26e-14

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 70.47  E-value: 2.26e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  10 VHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQRF 89
Cdd:TIGR01189   3 ARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEPHENILYLGHLP 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  90 TYWEDLTVRENLDFVARLYEVRRRRERVDrmLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDP 169
Cdd:TIGR01189  83 GLKPELSALENLHFWAAIHGGAQRTIEDA--LAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDK 160
                         170       180
                  ....*....|....*....|....*
gi 1422354951 170 SARREFWEELHRLAARGISVLVSTH 194
Cdd:TIGR01189 161 AGVALLAGLLRAHLARGGIVLLTTH 185
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
8-222 3.55e-14

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 70.93  E-value: 3.55e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDI---------TKQSREI 78
Cdd:PRK11264    4 IEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIdtarslsqqKGLIRQL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  79 KRRVGYMTQRFTYWEDLTVRENL---DFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEP 155
Cdd:PRK11264   84 RQHVGFVFQNFNLFPHRTVLENIiegPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRP 163
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 156 ELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYM----DEAERChklAYISYGVLLAQGEARDL 222
Cdd:PRK11264  164 EVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMsfarDVADRA---IFMDQGRIVEQGPAKAL 231
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
5-62 4.79e-14

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 72.28  E-value: 4.79e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951   5 DLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:TIGR03719 320 DKVIEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSG 377
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
18-226 5.89e-14

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 72.10  E-value: 5.89e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE-IKRRVGYMTQRfTYWEDLT 96
Cdd:COG4988   348 GGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPAsWRRQIAWVPQN-PYLFAGT 426
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  97 VRENL----------------------DFVARLyevrrrrervDRMLDElRLGSRAKQLagslSGGWKQRlalaaallqe 154
Cdd:COG4988   427 IRENLrlgrpdasdeeleaaleaagldEFVAAL----------PDGLDT-PLGEGGRGL----SGGQAQRlalarallrd 491
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 155 pelllldepTAGVDPSARREFWEELHRLaARGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQ 226
Cdd:COG4988   492 aplllldepTAHLDAETEAEILQALRRL-AKGRTVILITHRLALLAQADRILVLDDGRIVEQGTHEELLAKN 562
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
7-144 5.91e-14

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 71.40  E-value: 5.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITkQSREIKRRVGYMT 86
Cdd:PRK11607   19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLS-HVPPYQRPINMMF 97
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRFTYWEDLTVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:PRK11607   98 QSYALFPHMTVEQNIAFGLKQdkLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQR 157
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
8-199 6.39e-14

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 69.67  E-value: 6.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVvKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREiKRRVGYMTQ 87
Cdd:cd03299     1 LKVENLSKDWKEFKL-KNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPE-KRDISYVPQ 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTYWEDLTVRENLDFVARLyevrrrrervdRMLDELRLGSRAKQLA-------------GSLSGGWKQRLALAAALLQE 154
Cdd:cd03299    79 NYALFPHMTVYKNIAYGLKK-----------RKVDKKEIERKVLEIAemlgidhllnrkpETLSGGEQQRVAIARALVVN 147
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1422354951 155 PELLLLDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEA 199
Cdd:cd03299   148 PKILLLDEPFSALDVRTKEKLREELKKIRKEfGVTVLHVTHDFEEA 193
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
5-228 1.31e-13

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 68.96  E-value: 1.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   5 DLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCL------GYDItkqsREI 78
Cdd:COG1119     1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVRLfgerrgGEDV----WEL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  79 KRRVGY----MTQRFTywEDLTVRenlDFVA-------RLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQRl 145
Cdd:COG1119    77 RKRIGLvspaLQLRFP--RDETVL---DVVLsgffdsiGLYREPTDEQREraRELLELLGLAHLADRPFGTLSQGEQRRv 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 146 alaaallqepellllDEPTAGVDPSARREFWEELHRLAARGI--SVLVsTHYMDEAERC--HKLAyISYGVLLAQGEARD 221
Cdd:COG1119   152 liaralvkdpellilDEPTAGLDLGARELLLALLDKLAAEGAptLVLV-THHVEEIPPGitHVLL-LKDGRVVAAGPKEE 229

                  ....*..
gi 1422354951 222 LIRQQAL 228
Cdd:COG1119   230 VLTSENL 236
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
5-62 2.08e-13

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 70.53  E-value: 2.08e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951   5 DLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:PRK11819  322 DKVIEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSG 379
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
7-144 3.64e-13

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 68.25  E-value: 3.64e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR----EIKRRV 82
Cdd:PRK11831    7 LVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRsrlyTVRKRM 86
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951  83 GYMTQRFTYWEDLTVRENLDFVARLYEVRRRRERVDRMLDELR-LGSR--AKQLAGSLSGGWKQR 144
Cdd:PRK11831   87 SMLFQSGALFTDMNVFDNVAYPLREHTQLPAPLLHSTVMMKLEaVGLRgaAKLMPSELSGGMARR 151
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
5-101 5.67e-13

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 68.90  E-value: 5.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   5 DLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT-KQSRE-IKRRV 82
Cdd:COG3845     3 PPALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRiRSPRDaIALGI 82
                          90
                  ....*....|....*....
gi 1422354951  83 GYMTQRFTYWEDLTVRENL 101
Cdd:COG3845    83 GMVHQHFMLVPNLTVAENI 101
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
8-218 5.67e-13

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 69.06  E-value: 5.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGL--LTPDSGH-----GTC-------------- 66
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRiiyhvALCekcgyverpskvge 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  67 ----LGYDITKQ-----------SREIKRRVGYMTQR-FTYWEDLTVREN-LDFVARL-YEVRRRRERVDRMLDELRLGS 128
Cdd:TIGR03269  81 pcpvCGGTLEPEevdfwnlsdklRRRIRKRIAIMLQRtFALYGDDTVLDNvLEALEEIgYEGKEAVGRAVDLIEMVQLSH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 129 RAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREFWEELHRLA-ARGISVLVSTHYmdeAERCHKLAy 207
Cdd:TIGR03269 161 RITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVkASGISMVLTSHW---PEVIEDLS- 236
                         250
                  ....*....|.
gi 1422354951 208 iSYGVLLAQGE 218
Cdd:TIGR03269 237 -DKAIWLENGE 246
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
23-227 5.80e-13

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 68.52  E-value: 5.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS----REIKRR-VGYMTQRFTYWEDLTV 97
Cdd:PRK10070   44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISdaelREVRRKkIAMVFQSFALMPHMTV 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDFVARLyEVRRRRERVDRMLDELR---LGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARRE 174
Cdd:PRK10070  124 LDNTAFGMEL-AGINAEERREKALDALRqvgLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTE 202
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 175 FWEELHRLAAR-GISVLVSTHYMDEAERC-HKLAYISYGVLLAQGEARDLIRQQA 227
Cdd:PRK10070  203 MQDELVKLQAKhQRTIVFISHDLDEAMRIgDRIAIMQNGEVVQVGTPDEILNNPA 257
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
8-87 6.18e-13

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 65.16  E-value: 6.18e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyDITKQSREikrRVGYMTQ 87
Cdd:cd03221     1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEG-------IVTWGSTV---KIGYFEQ 70
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
20-198 7.67e-13

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 65.53  E-value: 7.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  20 RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE--IKRRVGYMTqrftywED--- 94
Cdd:cd03215    13 KGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRdaIRAGIAYVP------EDrkr 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  95 ------LTVRENLdfvarlyevrrrrervdrmldelrlgsrakQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVD 168
Cdd:cd03215    87 eglvldLSVAENI------------------------------ALSSLLSGGNQQKVVLARWLARDPRVLILDEPTRGVD 136
                         170       180       190
                  ....*....|....*....|....*....|
gi 1422354951 169 PSARREFWEELHRLAARGISVLVSTHYMDE 198
Cdd:cd03215   137 VGAKAEIYRLIRELADAGKAVLLISSELDE 166
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
9-194 8.28e-13

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 66.13  E-value: 8.28e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   9 DVHRLNKRFGD-RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLtpDSGHGTCLGYDITKQSREIKRRVGYMTQ 87
Cdd:cd03226     1 RIENISFSYKKgTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLI--KESSGSILLNGKPIKAKERRKSIGYVMQ 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 RFTY--WEDlTVRENLDFVARLYEVRRRRERVdrMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTA 165
Cdd:cd03226    79 DVDYqlFTD-SVREELLLGLKELDAGNEQAET--VLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTS 155
                         170       180
                  ....*....|....*....|....*....
gi 1422354951 166 GVDPSARREFWEELHRLAARGISVLVSTH 194
Cdd:cd03226   156 GLDYKNMERVGELIRELAAQGKAVIVITH 184
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
1-205 8.83e-13

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 66.28  E-value: 8.83e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKR 80
Cdd:PRK10247    1 MQENSPLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  81 R-VGYMTQRFTYWEDlTVRENLDFVarlYEVRRRRERVDRMLDEL-RLG---SRAKQLAGSLSGGWKQRLALAAALLQEP 155
Cdd:PRK10247   81 QqVSYCAQTPTLFGD-TVYDNLIFP---WQIRNQQPDPAIFLDDLeRFAlpdTILTKNIAELSGGEKQRISLIRNLQFMP 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 156 ELLLLDEPTAGVDPSARREFWEELHRLAA-RGISVLVSTHYMDEAERCHKL 205
Cdd:PRK10247  157 KVLLLDEITSALDESNKHNVNEIIHRYVReQNIAVLWVTHDKDEINHADKV 207
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
22-225 9.15e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 67.03  E-value: 9.15e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  22 VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR--EIKRRVGYMTQR-------FTYW 92
Cdd:PRK13633   25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENlwDIRNKAGMVFQNpdnqivaTIVE 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  93 EDLTV-RENLDFVARLYEVRRRRERVDRMLDELRlgSRAKQLagsLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSA 171
Cdd:PRK13633  105 EDVAFgPENLGIPPEEIRERVDESLKKVGMYEYR--RHAPHL---LSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSG 179
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 172 RREFWEELHRLAAR-GISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:PRK13633  180 RREVVNTIKELNKKyGITIILITHYMEEAVEADRIIVMDSGKVVMEGTPKEIFKE 234
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
17-259 1.04e-12

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 66.93  E-value: 1.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  17 FGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK-QSREIKRRVGYMTQRFTYWEDL 95
Cdd:PRK10253   17 YGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHyASKEVARRIGLLAQNATTPGDI 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  96 TVREnldFVARLYEVRRRRERVDRMLDE------LR---LGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAG 166
Cdd:PRK10253   97 TVQE---LVARGRYPHQPLFTRWRKEDEeavtkaMQatgITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTW 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 167 VDPSARREFWEELHRL-AARGISVLVSTHYMDEAER--CHKLAyISYGVLLAQGEARDLIRQQALHTwaVSGANLVGLND 243
Cdd:PRK10253  174 LDISHQIDLLELLSELnREKGYTLAAVLHDLNQACRyaSHLIA-LREGKIVAQGAPKEIVTAELIER--IYGLRCMIIDD 250
                         250
                  ....*....|....*.
gi 1422354951 244 RLQGQPGVeqiVAFGR 259
Cdd:PRK10253  251 PVAGTPLV---VPLGR 263
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
5-226 1.48e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 66.68  E-value: 1.48e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   5 DLLIDVHRLNKRFGD-RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRV 82
Cdd:PRK13647    2 DNIIEVEDLHFRYKDgTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENeKWVRSKV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 GYMTQ-------RFTYWEDLT---VRENLDfvarlyeVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALL 152
Cdd:PRK13647   82 GLVFQdpddqvfSSTVWDDVAfgpVNMGLD-------KDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLA 154
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 153 QEPELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMD-EAERCHKLAYISYGVLLAQGEARDLIRQQ 226
Cdd:PRK13647  155 MDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDlAAEWADQVIVLKEGRVLAEGDKSLLTDED 229
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
16-201 1.58e-12

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 64.95  E-value: 1.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  16 RFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgTClgyditkqSREIKRRVGYMTQRFTYWEDL 95
Cdd:NF040873    1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSG--TV--------RRAGGARVAYVPQRSEVPDSL 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  96 --TVRE--NLDFVARL----YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGV 167
Cdd:NF040873   71 plTVRDlvAMGRWARRglwrRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGL 150
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1422354951 168 DPSARREFWEELHRLAARGISVLVSTHYMDEAER 201
Cdd:NF040873  151 DAESRERIIALLAEEHARGATVVVVTHDLELVRR 184
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
18-234 2.41e-12

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 67.10  E-value: 2.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE-IKRRVGYMTQRfTYWEDLT 96
Cdd:COG4987   346 AGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDdLRRRIAVVPQR-PHLFDTT 424
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  97 VRENLDFV------ARLYEvrrrrervdrMLDELRLGSRAKQL----------AGS-LSGGWKQRlalaaallqepelll 159
Cdd:COG4987   425 LRENLRLArpdatdEELWA----------ALERVGLGDWLAALpdgldtwlgeGGRrLSGGERRRlalarallrdapill 494
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 160 ldepTAGVDPSARREFWEELHRlAARGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQALHTWAVS 234
Cdd:COG4987   495 ldepTEGLDAATEQALLADLLE-ALAGRTVLLITHRLAGLERMDRILVLEDGRIVEQGTHEELLAQNGRYRQLYQ 568
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
7-219 4.41e-12

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 64.38  E-value: 4.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDR----HVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE----- 77
Cdd:COG4181     8 IIELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDararl 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  78 IKRRVGYMTQRFTYWEDLTVRENLDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPEL 157
Cdd:COG4181    88 RARHVGFVFQSFQLLPTLTALENVMLPLELAGRRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPAI 167
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 158 LLLDEPTAGVDPSARREFWEELHRL-AARGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEA 219
Cdd:COG4181   168 LFADEPTGNLDAATGEQIIDLLFELnRERGTTLVLVTHDPALAARCDRVLRLRAGRLVEDTAA 230
cbiO PRK13644
energy-coupling factor transporter ATPase;
23-246 5.71e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 65.01  E-value: 5.71e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR--EIKRRVGYMTQR-FTYWEDLTVRE 99
Cdd:PRK13644   18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKlqGIRKLVGIVFQNpETQFVGRTVEE 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 100 NLDFVAR--LYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREFWE 177
Cdd:PRK13644   98 DLAFGPEnlCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVLE 177
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951 178 ELHRLAARGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQALHTWAVSGANLVGLNDRLQ 246
Cdd:PRK13644  178 RIKKLHEKGKTIVYITHNLEELHDADRIIVMDRGKIVLEGEPENVLSDVSLQTLGLTPPSLIELAENLK 246
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
15-198 9.42e-12

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 65.42  E-value: 9.42e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  15 KRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLG--YDITKQSREIKRRVGYMTqrftyw 92
Cdd:COG1129   260 EGLSVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGkpVRIRSPRDAIRAGIAYVP------ 333
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  93 ED---------LTVREN-----LDFVAR--LYEVRRRRERVDRMLDELRL-GSRAKQLAGSLSGGWKQRlalaaallqep 155
Cdd:COG1129   334 EDrkgeglvldLSIRENitlasLDRLSRggLLDRRRERALAEEYIKRLRIkTPSPEQPVGNLSGGNQQKvvlakwlatdp 413
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1422354951 156 elllldepTAGVDPSARREFWEELHRLAARGISVLVSTHYMDE 198
Cdd:COG1129   414 kvlildepTRGIDVGAKAEIYRLIRELAAEGKAVIVISSELPE 456
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
4-107 1.29e-11

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 64.65  E-value: 1.29e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   4 DDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-RE-IKRR 81
Cdd:COG1129     1 AEPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSpRDaQAAG 80
                          90       100
                  ....*....|....*....|....*.
gi 1422354951  82 VGYMTQRFTYWEDLTVRENLdFVARL 107
Cdd:COG1129    81 IAIIHQELNLVPNLSVAENI-FLGRE 105
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
8-222 1.45e-11

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 63.45  E-value: 1.45e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT--------------K 73
Cdd:PRK10619    6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdkdgqlkvadkN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  74 QSREIKRRVGYMTQRFTYWEDLTVRENL--DFVARL-YEVRRRRERVDRMLDELRLGSRAKQ-LAGSLSGGWKQRLALAA 149
Cdd:PRK10619   86 QLRLLRTRLTMVFQHFNLWSHMTVLENVmeAPIQVLgLSKQEARERAVKYLAKVGIDERAQGkYPVHLSGGQQQRVSIAR 165
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1422354951 150 ALLQEPELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAERCHK-LAYISYGVLLAQGEARDL 222
Cdd:PRK10619  166 ALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSShVIFLHQGKIEEEGAPEQL 239
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
12-227 1.63e-11

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 62.85  E-value: 1.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  12 RLNKRFGDRHvvKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREiKRRVGYMTQRFTY 91
Cdd:COG3840     6 DLTYRYGDFP--LRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPA-ERPVSMLFQENNL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  92 WEDLTVREN--LDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepelllldepTA---- 165
Cdd:COG3840    83 FPHLTVAQNigLGLRPGLKLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQR-------------------VAlarc 143
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951 166 ---------------GVDPSARREFWEELHRLAA-RGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQA 227
Cdd:COG3840   144 lvrkrpillldepfsALDPALRQEMLDLVDELCReRGLTVLMVTHDPEDAARiADRVLLVADGRIAADGPTAALLDGEP 222
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
18-100 1.83e-11

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 61.46  E-value: 1.83e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRR-VGYMTQRFTYWEDlT 96
Cdd:cd03246    13 AEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDhVGYLPQDDELFSG-S 91

                  ....
gi 1422354951  97 VREN 100
Cdd:cd03246    92 IAEN 95
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
18-144 5.11e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 61.04  E-value: 5.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITkqSREIKRRVGYMTQRFTYWEDLTV 97
Cdd:PRK13539   13 GGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDID--DPDVAEACHYLGHRNAMKPALTV 90
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1422354951  98 RENLDFVARLYEVRRRRERVDrmLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:PRK13539   91 AENLEFWAAFLGGEELDIAAA--LEAVGLAPLAHLPFGYLSAGQKRR 135
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
7-107 6.65e-11

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 62.88  E-value: 6.65e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREI--KRRVGY 84
Cdd:PRK09700    5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLaaQLGIGI 84
                          90       100
                  ....*....|....*....|...
gi 1422354951  85 MTQRFTYWEDLTVRENLdFVARL 107
Cdd:PRK09700   85 IYQELSVIDELTVLENL-YIGRH 106
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
1-218 6.83e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 61.55  E-value: 6.83e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNADDLLIDVHRLNKRFGDRH--VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-RE 77
Cdd:PRK13632    1 IKNKSVMIKVENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENlKE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  78 IKRRVGYMTQ----RFTyweDLTVRENLDF------VAR--LYEVRRRRERVDRMLDELrlgsraKQLAGSLSGGWKQRL 145
Cdd:PRK13632   81 IRKKIGIIFQnpdnQFI---GATVEDDIAFglenkkVPPkkMKDIIDDLAKKVGMEDYL------DKEPQNLSGGQKQRV 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1422354951 146 ALAAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVS-THYMDEAERCHKLAYISYGVLLAQGE 218
Cdd:PRK13632  152 AIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISiTHDMDEAILADKVIVFSEGKLIAQGK 225
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
7-88 1.02e-10

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 60.90  E-value: 1.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyditKQSREIKRRVGYMT 86
Cdd:PRK09544    4 LVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEG----------VIKRNGKLRIGYVP 73

                  ..
gi 1422354951  87 QR 88
Cdd:PRK09544   74 QK 75
cbiO PRK13649
energy-coupling factor transporter ATPase;
25-279 1.09e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 61.30  E-value: 1.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  25 DLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-----REIKRRVGYMtqrFTYWE----DL 95
Cdd:PRK13649   25 DVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSknkdiKQIRKKVGLV---FQFPEsqlfEE 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  96 TVRENLDFVARLYEVRRRRERVDRmLDELRLGSRAKQLAG----SLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSA 171
Cdd:PRK13649  102 TVLKDVAFGPQNFGVSQEEAEALA-REKLALVGISESLFEknpfELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKG 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 172 RREFWEELHRLAARGISVLVSTHYMDEAERCHKLAYI-SYGVLLAQGEARDLIRQQALhtwavsganlvgLNDRlqgQPG 250
Cdd:PRK13649  181 RKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVlEKGKLVLSGKPKDIFQDVDF------------LEEK---QLG 245
                         250       260
                  ....*....|....*....|....*....
gi 1422354951 251 VEQIVAFGRSLHVSGGDPERLESSLNELK 279
Cdd:PRK13649  246 VPKITKFAQRLADRGISFSSLPITIEEFR 274
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
8-229 1.13e-10

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 62.16  E-value: 1.13e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRH--VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH---GtclGYDITKQS-REIKRR 81
Cdd:COG2274   474 IELENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRiliD---GIDLRQIDpASLRRQ 550
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  82 VGYMTQRFTYWEDlTVRENL----------------------DFVARL---YevrrrrervdrmldELRLGSRAkqlaGS 136
Cdd:COG2274   551 IGVVLQDVFLFSG-TIRENItlgdpdatdeeiieaarlaglhDFIEALpmgY--------------DTVVGEGG----SN 611
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 137 LSGGWKQRlalaaallqepellllDEPTAGVDPSARREFWEELHRLaARGISVLVSTHYMDEAERCHKLAYISYGVLLAQ 216
Cdd:COG2274   612 LSGGQRQRlaiarallrnprililDEATSALDAETEAIILENLRRL-LKGRTVIIIAHRLSTIRLADRIIVLDKGRIVED 690
                         250
                  ....*....|...
gi 1422354951 217 GEARDLIRQQALH 229
Cdd:COG2274   691 GTHEELLARKGLY 703
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
18-194 1.24e-10

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 59.81  E-value: 1.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQRFTYWEDLTV 97
Cdd:cd03231    11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLLYLGHAPGIKTTLSV 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDFVARLYEVRRRRERvdrmLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREFWE 177
Cdd:cd03231    91 LENLRFWHADHSDEQVEEA----LARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAE 166
                         170
                  ....*....|....*..
gi 1422354951 178 ELHRLAARGISVLVSTH 194
Cdd:cd03231   167 AMAGHCARGGMVVLTTH 183
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
12-232 1.24e-10

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 61.27  E-value: 1.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  12 RLNKRFGDRHVvkDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH----GTCLgYDitkQSREI-----KRRV 82
Cdd:COG4148     6 DFRLRRGGFTL--DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRirlgGEVL-QD---SARGIflpphRRRI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 GYMTQrftywED-----LTVRENLDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRlalaaallqepel 157
Cdd:COG4148    80 GYVFQ-----EArlfphLSVRGNLLYGRKRAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRvaigrallssprl 154
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951 158 lllDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQALHTWA 232
Cdd:COG4148   155 llmDEPLAALDLARKAEILPYLERLRDElDIPILYVSHSLDEVARlADHVVLLEQGRVVASGPLAEVLSRPDLLPLA 231
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
18-144 1.48e-10

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 61.72  E-value: 1.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE-IKRRVGYMTQ---RFtywe 93
Cdd:COG1132   351 GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLEsLRRQIGVVPQdtfLF---- 426
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1422354951  94 DLTVRENL----------------------DFVARL---YevrrrrervdrmldELRLGSRAkqlaGSLSGGWKQR 144
Cdd:COG1132   427 SGTIRENIrygrpdatdeeveeaakaaqahEFIEALpdgY--------------DTVVGERG----VNLSGGQRQR 484
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
8-222 1.84e-10

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 60.31  E-value: 1.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGL--LTPD---SGHGTCLGYDITKQS-REIKRR 81
Cdd:PRK14247    4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLieLYPEarvSGEVYLDGQDIFKMDvIELRRR 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  82 VGYMTQ------RFTYWEDLTVRENLDFVAR----LYEVRRRRERVDRMLDELRlgSRAKQLAGSLSGGWKQRLALAAAL 151
Cdd:PRK14247   84 VQMVFQipnpipNLSIFENVALGLKLNRLVKskkeLQERVRWALEKAQLWDEVK--DRLDAPAGKLSGGQQQRLCIARAL 161
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 152 LQEPELLLLDEPTAGVDPSARREFwEELHRLAARGISVLVSTHYMDEAERCHK-LAYISYGVLLAQGEARDL 222
Cdd:PRK14247  162 AFQPEVLLADEPTANLDPENTAKI-ESLFLELKKDMTIVLVTHFPQQAARISDyVAFLYKGQIVEWGPTREV 232
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
26-228 2.05e-10

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 59.95  E-value: 2.05e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  26 LSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLtPDSGH----GTCLGydiTKQSREIKRRVGYMTQR---------FTYW 92
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSiqfaGQPLE---AWSAAELARHRAYLSQQqtppfampvFQYL 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  93 E----DLT----VRENLDFVARLyevrrrrervdrmldeLRLGSRAKQLAGSLSGGWKQRLALaaallqepelllldept 164
Cdd:PRK03695   91 TlhqpDKTrteaVASALNEVAEA----------------LGLDDKLGRSVNQLSGGEWQRVRL----------------- 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 165 AGV--------DPSARREFWEE----------------LHRLAARGISVLVSTHYMDE-AERCHKLAYISYGVLLAQGEA 219
Cdd:PRK03695  138 AAVvlqvwpdiNPAGQLLLLDEpmnsldvaqqaaldrlLSELCQQGIAVVMSSHDLNHtLRHADRVWLLKQGKLLASGRR 217

                  ....*....
gi 1422354951 220 RDLIRQQAL 228
Cdd:PRK03695  218 DEVLTPENL 226
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
13-78 2.38e-10

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 60.50  E-value: 2.38e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951  13 LNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK---QSREI 78
Cdd:PRK11432   12 ITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHrsiQQRDI 80
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
18-228 2.57e-10

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 59.82  E-value: 2.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMTQR-------F 89
Cdd:PRK13652   15 GSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENiREVRKFVGLVFQNpddqifsP 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  90 TYWEDLTVRE-NLDFVARLYEVRRRRERVDRMLDELRlgsraKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVD 168
Cdd:PRK13652   95 TVEQDIAFGPiNLGLDEETVAHRVSSALHMLGLEELR-----DRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLD 169
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 169 PSARREFWEELHRLAAR-GISVLVSTHYMD-EAERCHKLAYISYGVLLAQGEARDLIRQQAL 228
Cdd:PRK13652  170 PQGVKELIDFLNDLPETyGMTVIFSTHQLDlVPEMADYIYVMDKGRIVAYGTVEEIFLQPDL 231
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
14-194 2.74e-10

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 59.21  E-value: 2.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  14 NKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLtpdSGHGTCLGyDITKQSREIKR-----RVGYMTQR 88
Cdd:cd03234    14 KNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRV---EGGGTTSG-QILFNGQPRKPdqfqkCVAYVRQD 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  89 FTYWEDLTVRENLDFVARLYEVRRRRERVDRMLDE------LRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDE 162
Cdd:cd03234    90 DILLPGLTVRETLTYTAILRLPRKSSDAIRKKRVEdvllrdLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDE 169
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1422354951 163 PTAGVDPSARREFWEELHRLAARGISVLVSTH 194
Cdd:cd03234   170 PTSGLDSFTALNLVSTLSQLARRNRIVILTIH 201
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
1-144 2.79e-10

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 59.41  E-value: 2.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNADDLLiDVHRLNKRFGD-RHVVKDLS---MQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR 76
Cdd:PRK10584    1 MPAENIV-EVHHLKKSVGQgEHELSILTgveLVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDE 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951  77 EIK-----RRVGYMTQRFTYWEDLTVRENLDFVARLY--EVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:PRK10584   80 EARaklraKHVGFVFQSFMLIPTLNALENVELPALLRgeSSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQR 154
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
20-229 3.33e-10

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 59.04  E-value: 3.33e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  20 RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDI-TKQSREIKRRVGYMTQRFTYWeDLTVR 98
Cdd:cd03252    15 PVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLaLADPAWLRRQVGVVLQENVLF-NRSIR 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  99 ENLDF------------VARLyevrrrrERVDRMLDELRLGSraKQLAG----SLSGGWKQRLALAAALLQEPELLLLDE 162
Cdd:cd03252    94 DNIALadpgmsmervieAAKL-------AGAHDFISELPEGY--DTIVGeqgaGLSGGQRQRIAIARALIHNPRILIFDE 164
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951 163 PTAGVDPSARREFWEELHRLAArGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQALH 229
Cdd:cd03252   165 ATSALDYESEHAIMRNMHDICA-GRTVIIIAHRLSTVKNADRIIVMEKGRIVEQGSHDELLAENGLY 230
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
18-194 3.34e-10

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 58.33  E-value: 3.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCL--GYDITKQSreIKRRVGYMTQRFTYWEDL 95
Cdd:cd03213    20 SGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLGVSGEVLinGRPLDKRS--FRKIIGYVPQDDILHPTL 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  96 TVRENLDFVArlyevrrrrervdrmldELRlgsrakqlagSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREF 175
Cdd:cd03213    98 TVRETLMFAA-----------------KLR----------GLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQV 150
                         170
                  ....*....|....*....
gi 1422354951 176 WEELHRLAARGISVLVSTH 194
Cdd:cd03213   151 MSLLRRLADTGRTIICSIH 169
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
8-220 4.04e-10

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 59.09  E-value: 4.04e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGL--LTPDS---GHGTCLGYDITKQSR---EIK 79
Cdd:PRK14267    5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLleLNEEArveGEVRLFGRNIYSPDVdpiEVR 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  80 RRVGYMTQRFTYWEDLTVRENLDFVARLYEVRRRRE----------RVDRMLDELRlgSRAKQLAGSLSGGWKQRLALAA 149
Cdd:PRK14267   85 REVGMVFQYPNPFPHLTIYDNVAIGVKLNGLVKSKKeldervewalKKAALWDEVK--DRLNDYPSNLSGGQRQRLVIAR 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 150 ALLQEPELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVsTHYMDEAERCHK-LAYISYGVLLAQGEAR 220
Cdd:PRK14267  163 ALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLV-THSPAQAARVSDyVAFLYLGKLIEVGPTR 233
cbiO PRK13640
energy-coupling factor transporter ATPase;
20-228 4.55e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 59.43  E-value: 4.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  20 RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHG---TCLGYDITKQSR-EIKRRVGYMTQ----RFTy 91
Cdd:PRK13640   20 KPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNskiTVDGITLTAKTVwDIREKVGIVFQnpdnQFV- 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  92 weDLTVRENLDF--VARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDP 169
Cdd:PRK13640   99 --GATVGDDVAFglENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDP 176
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 170 SARREFWEELHRLAA-RGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQAL 228
Cdd:PRK13640  177 AGKEQILKLIRKLKKkNNLTVISITHDIDEANMADQVLVLDDGKLLAQGSPVEIFSKVEM 236
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
18-107 4.76e-10

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 58.28  E-value: 4.76e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQRFTYWEDLTV 97
Cdd:PRK13538   12 DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEYHQDLLYLGHQPGIKTELTA 91
                          90
                  ....*....|
gi 1422354951  98 RENLDFVARL 107
Cdd:PRK13538   92 LENLRFYQRL 101
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
19-217 6.28e-10

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 57.32  E-value: 6.28e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  19 DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQRfTYWEDLTVR 98
Cdd:cd03247    14 EQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSLISVLNQR-PYLFDTTLR 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  99 ENLdfvarlyevrrrrervdrmldelrlGSRakqlagsLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREFWEE 178
Cdd:cd03247    93 NNL-------------------------GRR-------FSGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQLLSL 140
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1422354951 179 LHRlAARGISVLVSTHYMDEAERCHKLAYISYGVLLAQG 217
Cdd:cd03247   141 IFE-VLKDKTLIWITHHLTGIEHMDKILFLENGKIIMQG 178
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
19-194 7.77e-10

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 57.98  E-value: 7.77e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  19 DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMTQRFTYWEDlTV 97
Cdd:cd03245    16 EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDpADLRRNIGYVPQDVTLFYG-TL 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDF------------VARLYEVRRRRERVDRMLDeLRLGSRAKqlagSLSGGWKQRLALAAALLQEPELLLLDEPTA 165
Cdd:cd03245    95 RDNITLgapladderilrAAELAGVTDFVNKHPNGLD-LQIGERGR----GLSGGQRQAVALARALLNDPPILLLDEPTS 169
                         170       180
                  ....*....|....*....|....*....
gi 1422354951 166 GVDPSARREFWEELHRLaARGISVLVSTH 194
Cdd:cd03245   170 AMDMNSEERLKERLRQL-LGDKTLIIITH 197
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
6-101 8.98e-10

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 59.58  E-value: 8.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   6 LLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH---GTclgyditkqsreiKRRV 82
Cdd:PRK11147  318 IVFEMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRihcGT-------------KLEV 384
                          90       100
                  ....*....|....*....|...
gi 1422354951  83 GYMTQrftYWEDL----TVRENL 101
Cdd:PRK11147  385 AYFDQ---HRAELdpekTVMDNL 404
PLN03211 PLN03211
ABC transporter G-25; Provisional
15-194 9.52e-10

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 59.51  E-value: 9.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  15 KRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDiTKQSREIKRRVGYMTQRFTYWED 94
Cdd:PLN03211   76 RQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNFTGTILANN-RKPTKQILKRTGFVTQDDILYPH 154
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  95 LTVRENLDFVARL-----YEVRRRRERVDRMLDELRLGSRAKQLAGS-----LSGGWKQRLALAAALLQEPELLLLDEPT 164
Cdd:PLN03211  155 LTVRETLVFCSLLrlpksLTKQEKILVAESVISELGLTKCENTIIGNsfirgISGGERKRVSIAHEMLINPSLLILDEPT 234
                         170       180       190
                  ....*....|....*....|....*....|
gi 1422354951 165 AGVDPSARREFWEELHRLAARGISVLVSTH 194
Cdd:PLN03211  235 SGLDATAAYRLVLTLGSLAQKGKTIVTSMH 264
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
8-217 1.05e-09

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 58.66  E-value: 1.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRF----GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS----REIK 79
Cdd:PRK11153    2 IELKNISKVFpqggRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSekelRKAR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  80 RRVGYMTQRFTYWEDLTVRENLDF---------------VARLyevrrrrervdrmLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:PRK11153   82 RQIGMIFQHFNLLSSRTVFDNVALplelagtpkaeikarVTEL-------------LELVGLSDKADRYPAQLSGGQKQR 148
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 145 LALAAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQG 217
Cdd:PRK11153  149 VAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHEMDVVKRiCDRVAVIDAGRLVEQG 223
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
16-228 1.80e-09

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 57.49  E-value: 1.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  16 RFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK-QSREIKRRVGYMTQRFTYWED 94
Cdd:PRK10575   20 RVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVAYLPQQLPAAEG 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  95 LTVREnLDFVARL-------YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGV 167
Cdd:PRK10575  100 MTVRE-LVAIGRYpwhgalgRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSAL 178
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 168 DPSARREFWEELHRLA-ARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQAL 228
Cdd:PRK10575  179 DIAHQVDVLALVHRLSqERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAELMRGETL 241
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
18-194 2.17e-09

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 58.14  E-value: 2.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR-EIKRRVGYMTQR---Ftywe 93
Cdd:TIGR02868 346 GAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQdEVRRRVSVCAQDahlF---- 421
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  94 DLTVRENLdfvaRLYEVRRRRERVDRMLDELRLGSRAKQL-----------AGSLSGGWKQRLALAAALLQEPELLLLDE 162
Cdd:TIGR02868 422 DTTVRENL----RLARPDATDEELWAALERVGLADWLRALpdgldtvlgegGARLSGGERQRLALARALLADAPILLLDE 497
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1422354951 163 PTAGVDPSARREFWEELhRLAARGISVLVSTH 194
Cdd:TIGR02868 498 PTEHLDAETADELLEDL-LAALSGRTVVLITH 528
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
8-99 5.90e-09

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 56.82  E-value: 5.90e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyditkqsrEIK----RRVG 83
Cdd:PRK15064  320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSG--------------TVKwsenANIG 385
                          90
                  ....*....|....*...
gi 1422354951  84 YMTQRFTYW--EDLTVRE 99
Cdd:PRK15064  386 YYAQDHAYDfeNDLTLFD 403
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
17-201 7.37e-09

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 54.88  E-value: 7.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  17 FGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK-QSREI---KRRVGYMTQRFTYW 92
Cdd:PRK10908   12 LGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRlKNREVpflRRQIGMIFQDHHLL 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  93 EDLTVREN--LDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPS 170
Cdd:PRK10908   92 MDRTVYDNvaIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDA 171
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1422354951 171 ARR---EFWEELHRLaarGISVLVSTHYMDEAER 201
Cdd:PRK10908  172 LSEgilRLFEEFNRV---GVTVLMATHDIGLISR 202
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
1-222 9.66e-09

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 55.04  E-value: 9.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGL--LTPD---SGHGTCLGYDITKQS 75
Cdd:COG1117     5 ASTLEPKIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMndLIPGarvEGEILLDGEDIYDPD 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  76 R---EIKRRVGYMTQR---FTywedLTVRENLDFVARLYEVRRRRErvdrmLDEL----------------RLgsraKQL 133
Cdd:COG1117    85 VdvvELRRRVGMVFQKpnpFP----KSIYDNVAYGLRLHGIKSKSE-----LDEIveeslrkaalwdevkdRL----KKS 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 134 AGSLSGGWKQRlalaaallqepelllLDEPTAGVDP-SARRefWEEL-HRLAARgISVLVSTHYMDEAERC-HKLAYISY 210
Cdd:COG1117   152 ALGLSGGQQQRlciaralavepevllMDEPTSALDPiSTAK--IEELiLELKKD-YTIVIVTHNMQQAARVsDYTAFFYL 228
                         250
                  ....*....|..
gi 1422354951 211 GVLLAQGEARDL 222
Cdd:COG1117   229 GELVEFGPTEQI 240
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
19-236 1.00e-08

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 55.95  E-value: 1.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  19 DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS--REIKRRVGYMTQ--RFT-YWE 93
Cdd:PRK09700  275 DRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSplDAVKKGMAYITEsrRDNgFFP 354
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  94 DLTVRENLDFVARLYEVRRRRER-VDRMLDELRLGSRAKQL-----------AGSLSGGWKQRLALAAALLQEPELLLLD 161
Cdd:PRK09700  355 NFSIAQNMAISRSLKDGGYKGAMgLFHEVDEQRTAENQRELlalkchsvnqnITELSGGNQQKVLISKWLCCCPEVIIFD 434
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1422354951 162 EPTAGVDPSARREFWEELHRLAARGISVL-VSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQALHTWAVSGA 236
Cdd:PRK09700  435 EPTRGIDVGAKAEIYKVMRQLADDGKVILmVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMSEEEIMAWALPQE 510
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
4-228 1.00e-08

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 54.82  E-value: 1.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   4 DDLLIDVHRLNKRFGD----RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIK 79
Cdd:PRK11629    2 NKILLQCDNLCKRYQEgsvqTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAK 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  80 -----RRVGYMTQRFTYWEDLTVREN--LDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALL 152
Cdd:PRK11629   82 aelrnQKLGFIYQFHHLLPDFTALENvaMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALV 161
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951 153 QEPELLLLDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAERCHKlayisygvllaQGEARDLIRQQAL 228
Cdd:PRK11629  162 NNPRLVLADEPTGNLDARNADSIFQLLGELNRLqGTAFLVVTHDLQLAKRMSR-----------QLEMRDGRLTAEL 227
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
7-144 1.07e-08

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 55.08  E-value: 1.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRF---------GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE 77
Cdd:PRK10419    3 LLNVSGLSHHYahgglsgkhQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  78 IK---RR---------VGYMTQRFTYWEdlTVRENLDFVARLyEVRRRRERVDRMLDELRLG-SRAKQLAGSLSGGWKQR 144
Cdd:PRK10419   83 QRkafRRdiqmvfqdsISAVNPRKTVRE--IIREPLRHLLSL-DKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQR 159
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
29-101 1.12e-08

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 55.95  E-value: 1.12e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951  29 QVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyditkqSREIKRRVGYMTQRFTYWEDLTVRENL 101
Cdd:COG1245   362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEG------------EVDEDLKISYKPQYISPDYDGTVEEFL 422
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
23-199 1.22e-08

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 54.39  E-value: 1.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREikRRVGYMTQRFTYWedLTVRENL- 101
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPD--RMVVFQNYSLLPW--LTVRENIa 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 102 ---DFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREFWEE 178
Cdd:TIGR01184  77 lavDRVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEE 156
                         170       180
                  ....*....|....*....|..
gi 1422354951 179 LHRLAAR-GISVLVSTHYMDEA 199
Cdd:TIGR01184 157 LMQIWEEhRVTVLMVTHDVDEA 178
cbiO PRK13650
energy-coupling factor transporter ATPase;
7-87 1.98e-08

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 54.35  E-value: 1.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFG---DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR-EIKRRV 82
Cdd:PRK13650    4 IIEVKNLTFKYKedqEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVwDIRHKI 83

                  ....*
gi 1422354951  83 GYMTQ 87
Cdd:PRK13650   84 GMVFQ 88
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
30-144 2.14e-08

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 53.95  E-value: 2.14e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  30 VRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRvgymtqrftywEDLTVRENL-DFVARLY 108
Cdd:cd03237    22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSYKPQYIKAD-----------YEGTVRDLLsSITKDFY 90
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1422354951 109 evrRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:cd03237    91 ---THPYFKTEIAKPLQIEQILDREVPELSGGELQR 123
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
29-108 2.26e-08

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 55.20  E-value: 2.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  29 QVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyditkqSREIKRRVGYMTQRFTYWEDLTVRENLDFVARLY 108
Cdd:PRK13409  361 EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEG------------EVDPELKISYKPQYIKPDYDGTVEDLLRSITDDL 428
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
7-225 2.48e-08

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 54.81  E-value: 2.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFG--DRHVVK---DLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH-GTCLG---YDITKQSRE 77
Cdd:TIGR03269 279 IIKVRNVSKRYIsvDRGVVKavdNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEvNVRVGdewVDMTKPGPD 358
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  78 ----IKRRVGYMTQRFTYWEDLTVRENL------DFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLAL 147
Cdd:TIGR03269 359 grgrAKRYIGILHQEYDLYPHRTVLDNLteaiglELPDELARMKAVITLKMVGFDEEKAEEILDKYPDELSEGERHRVAL 438
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 148 AAALLQEPELLLLDEPTAGVDPSARREFWEELHRlaAR---GISVLVSTHYMDEA-ERCHKLAYISYGVLLAQGEARDLI 223
Cdd:TIGR03269 439 AQVLIKEPRIVILDEPTGTMDPITKVDVTHSILK--AReemEQTFIIVSHDMDFVlDVCDRAALMRDGKIVKIGDPEEIV 516

                  ..
gi 1422354951 224 RQ 225
Cdd:TIGR03269 517 EE 518
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
18-144 2.79e-08

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 54.75  E-value: 2.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE-IKRRVGYMTQR---Ftywe 93
Cdd:COG4618   343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREeLGRHIGYLPQDvelF---- 418
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951  94 DLTVRENldfVARLyevrrrrervdRMLDELRLgSRAKQLAG---------------------SLSGGWKQR 144
Cdd:COG4618   419 DGTIAEN---IARF-----------GDADPEKV-VAAAKLAGvhemilrlpdgydtrigeggaRLSGGQRQR 475
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
16-249 3.64e-08

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 53.47  E-value: 3.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  16 RFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG----HGTCLGYDiTKQSREIKRRVGYMTQ---R 88
Cdd:PRK13638   10 RYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGavlwQGKPLDYS-KRGLLALRQQVATVFQdpeQ 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  89 FTYWEDLtvreNLDFVARLYEVRRRRERVDRMLDELRLGSRAK----QLAGSLSGGWKQRLALAAALLQEPELLLLDEPT 164
Cdd:PRK13638   89 QIFYTDI----DSDIAFSLRNLGVPEAEITRRVDEALTLVDAQhfrhQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPT 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 165 AGVDPSARREFWEELHRLAARGISVLVSTHYMDEAERCHKLAYI-SYGVLLAQGEARDLI-RQQALHTWAVSGANLVGLN 242
Cdd:PRK13638  165 AGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVlRQGQILTHGAPGEVFaCTEAMEQAGLTQPWLVKLH 244

                  ....*..
gi 1422354951 243 DRLqGQP 249
Cdd:PRK13638  245 TQL-GLP 250
cbiO PRK13643
energy-coupling factor transporter ATPase;
14-217 4.26e-08

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 53.58  E-value: 4.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  14 NKRFGDRHVVkDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH---GTCLGYDITKQS--REIKRRVGYMTQ- 87
Cdd:PRK13643   14 NSPFASRALF-DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKvtvGDIVVSSTSKQKeiKPVRKKVGVVFQf 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  88 -RFTYWEDlTVRENLDFVARLYEVRRRRERVDRMlDELRLGSRAKQL----AGSLSGGWKQRLALAAALLQEPELLLLDE 162
Cdd:PRK13643   93 pESQLFEE-TVLKDVAFGPQNFGIPKEKAEKIAA-EKLEMVGLADEFweksPFELSGGQMRRVAIAGILAMEPEVLVLDE 170
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 163 PTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAERchklaYISYGVLLAQG 217
Cdd:PRK13643  171 PTAGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVAD-----YADYVYLLEKG 220
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
11-100 4.28e-08

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 54.17  E-value: 4.28e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  11 HRLNKRF-GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHgtclgydiTKQSREIKrrVGYMTQRF 89
Cdd:TIGR03719   8 NRVSKVVpPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGE--------ARPQPGIK--VGYLPQEP 77
                          90
                  ....*....|.
gi 1422354951  90 TYWEDLTVREN 100
Cdd:TIGR03719  78 QLDPTKTVREN 88
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
7-136 4.38e-08

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 52.54  E-value: 4.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSReiKRRVGYMT 86
Cdd:PRK13543   11 LLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDR--SRFMAYLG 88
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRFTYWEDLTVRENLDFVARLYevrrrrervdrmldelrlGSRAKQLAGS 136
Cdd:PRK13543   89 HLPGLKADLSTLENLHFLCGLH------------------GRRAKQMPGS 120
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
22-238 6.65e-08

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 52.77  E-value: 6.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  22 VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH----GTCLGYDiTKQSREIKRRVGYMTQR-----FTyw 92
Cdd:PRK13639   17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEvlikGEPIKYD-KKSLLEVRKTVGIVFQNpddqlFA-- 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  93 edLTVRENLDFvARLYEVRRRRERVDRMLDELR---LGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDP 169
Cdd:PRK13639   94 --PTVEEDVAF-GPLNLGLSKEEVEKRVKEALKavgMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDP 170
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 170 SARREFWEELHRLAARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIRQQALhtwaVSGANL 238
Cdd:PRK13639  171 MGASQIMKLLYDLNKEGITIIISTHDVDLVPVyADKVYVMSDGKIIKEGTPKEVFSDIET----IRKANL 236
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
7-208 9.25e-08

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 52.19  E-value: 9.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT--KQSREIKRRVGY 84
Cdd:PRK11614    5 MLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITdwQTAKIMREAVAI 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  85 MTQRFTYWEDLTVRENLDFVARLYEVRRRRERVDRMLDEL-RLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEP 163
Cdd:PRK11614   85 VPEGRRVFSRMTVEENLAMGGFFAERDQFQERIKWVYELFpRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEP 164
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1422354951 164 TAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAERCHKLAYI 208
Cdd:PRK11614  165 SLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYV 209
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
4-144 9.81e-08

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 51.89  E-value: 9.81e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   4 DDLLIDVHRLNKRFgdrhvvkdlSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREiKRRVG 83
Cdd:PRK10771    5 TDITWLYHHLPMRF---------DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPS-RRPVS 74
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951  84 YMTQRFTYWEDLTVREN--LDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:PRK10771   75 MLFQENNLFSHLTVAQNigLGLNPGLKLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQR 137
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
7-103 1.05e-07

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 51.49  E-value: 1.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMT 86
Cdd:PRK13540    1 MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLCTYQKQLCFVG 80
                          90
                  ....*....|....*..
gi 1422354951  87 QRFTYWEDLTVRENLDF 103
Cdd:PRK13540   81 HRSGINPYLTLRENCLY 97
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
1-201 1.09e-07

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 52.09  E-value: 1.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGL--LTPDSG-------HGTCLgYDI 71
Cdd:PRK14243    4 LNGTETVLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLndLIPGFRvegkvtfHGKNL-YAP 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  72 TKQSREIKRRVGYMTQRFTYWEDlTVRENLDFVAR-------LYEVRRRRERVDRMLDELRlgSRAKQLAGSLSGGWKQR 144
Cdd:PRK14243   83 DVDPVEVRRRIGMVFQKPNPFPK-SIYDNIAYGARingykgdMDELVERSLRQAALWDEVK--DKLKQSGLSLSGGQQQR 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951 145 LALAAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVsTHYMDEAER 201
Cdd:PRK14243  160 LCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQYTIIIV-THNMQQAAR 215
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
18-200 1.10e-07

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 51.33  E-value: 1.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPD-SGHGTCL--GYDITKQSREiKRRVGYMTQRFTYWED 94
Cdd:COG4136    12 GGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfSASGEVLlnGRRLTALPAE-QRRIGILFQDDLLFPH 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  95 LTVRENLDF-VARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARR 173
Cdd:COG4136    91 LSVGENLAFaLPPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAALRA 170
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1422354951 174 EF----WEELHrlaARGISVLVSTHYMDEAE 200
Cdd:COG4136   171 QFrefvFEQIR---QRGIPALLVTHDEEDAP 198
cbiO PRK13641
energy-coupling factor transporter ATPase;
25-198 1.12e-07

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 52.14  E-value: 1.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  25 DLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-----REIKRRVGYMTQ--RFTYWEDlTV 97
Cdd:PRK13641   25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETgnknlKKLRKKVSLVFQfpEAQLFEN-TV 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDFVARLYEVRRRRERVDRMLDELRLGSRAKQLAGS---LSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARRE 174
Cdd:PRK13641  104 LKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSEDLISKSpfeLSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKE 183
                         170       180
                  ....*....|....*....|....
gi 1422354951 175 FWEELHRLAARGISVLVSTHYMDE 198
Cdd:PRK13641  184 MMQLFKDYQKAGHTVILVTHNMDD 207
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
7-199 1.36e-07

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 51.62  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREikRRVGYMT 86
Cdd:PRK11248    1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAE--RGVVFQN 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRFTYWEDltVRENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPT 164
Cdd:PRK11248   79 EGLLPWRN--VQDNVAFGLQLagVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPF 156
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1422354951 165 AGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEA 199
Cdd:PRK11248  157 GALDAFTREQMQTLLLKLWQEtGKQVLLITHDIEEA 192
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
11-100 1.45e-07

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 52.43  E-value: 1.45e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  11 HRLNKRFG-DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCL-GYditkqsreikrRVGYMTQR 88
Cdd:PRK11819   10 NRVSKVVPpKKQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPApGI-----------KVGYLPQE 78
                          90
                  ....*....|..
gi 1422354951  89 FTYWEDLTVREN 100
Cdd:PRK11819   79 PQLDPEKTVREN 90
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
7-103 1.55e-07

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 52.36  E-value: 1.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVG-YM 85
Cdd:PRK15439   11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAKAHQLGiYL 90
                          90
                  ....*....|....*....
gi 1422354951  86 T-QRFTYWEDLTVRENLDF 103
Cdd:PRK15439   91 VpQEPLLFPNLSVKENILF 109
cbiO PRK13637
energy-coupling factor transporter ATPase;
23-225 1.63e-07

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 51.59  E-value: 1.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS---REIKRRVGYMTQRFTY--WEDlTV 97
Cdd:PRK13637   23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKvklSDIRKKVGLVFQYPEYqlFEE-TI 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDFVARlyevrrrrervDRMLDELRLGSRAKQ---LAG------------SLSGGWKQRLALAAALLQEPELLLLDE 162
Cdd:PRK13637  102 EKDIAFGPI-----------NLGLSEEEIENRVKRamnIVGldyedykdkspfELSGGQKRRVAIAGVVAMEPKILILDE 170
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 163 PTAGVDPSARREFWEELHRLAAR-GISVLVSTHYM-DEAERCHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:PRK13637  171 PTAGLDPKGRDEILNKIKELHKEyNMTIILVSHSMeDVAKLADRIIVMNKGKCELQGTPREVFKE 235
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
22-194 1.93e-07

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 52.42  E-value: 1.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  22 VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE---IKRR--VGYMTQRFTYWEDLT 96
Cdd:PRK10535   23 VLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADalaQLRRehFGFIFQRYHLLSHLT 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  97 VRENLDFVArLY---EVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARR 173
Cdd:PRK10535  103 AAQNVEVPA-VYaglERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGE 181
                         170       180
                  ....*....|....*....|.
gi 1422354951 174 EFWEELHRLAARGISVLVSTH 194
Cdd:PRK10535  182 EVMAILHQLRDRGHTVIIVTH 202
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
20-225 1.95e-07

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 52.43  E-value: 1.95e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  20 RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRR-VGYMTQRfTYWEDLTVR 98
Cdd:TIGR01193 487 SNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLRQfINYLPQE-PYIFSGSIL 565
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  99 ENLDFVARLYEVRRRRERVDRMLD--------ELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPS 170
Cdd:TIGR01193 566 ENLLLGAKENVSQDEIWAACEIAEikddienmPLGYQTELSEEGSSISGGQKQRIALARALLTDSKVLILDESTSNLDTI 645
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 171 ARREFWEELHRLAARGIsVLVStHYMDEAERCHKLAYISYGVLLAQGEARDLIRQ 225
Cdd:TIGR01193 646 TEKKIVNNLLNLQDKTI-IFVA-HRLSVAKQSDKIIVLDHGKIIEQGSHDELLDR 698
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
12-62 1.97e-07

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 50.26  E-value: 1.97e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1422354951  12 RLNKRFGDRHVVKDLSmQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:cd03222     5 DCVKRYGVFFLLVELG-VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGD 54
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
8-158 2.09e-07

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 50.85  E-value: 2.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQ-SREIKRRVGYMT 86
Cdd:COG4604     2 IEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTpSRELAKRLAILR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 Q------RftywedLTVRENLDF-----------------VARlyevrrrrervdrMLDELRLGSRAKQLAGSLSGGWKQ 143
Cdd:COG4604    82 QenhinsR------LTVRELVAFgrfpyskgrltaedreiIDE-------------AIAYLDLEDLADRYLDELSGGQRQ 142
                         170
                  ....*....|....*
gi 1422354951 144 RLALAAALLQEPELL 158
Cdd:COG4604   143 RAFIAMVLAQDTDYV 157
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
7-63 2.35e-07

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 51.08  E-value: 2.35e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH 63
Cdd:PRK11701    6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGE 62
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
2-222 2.97e-07

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 50.82  E-value: 2.97e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   2 NADDLLiDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLL-TPDS-----GHGTCLGYDITK-Q 74
Cdd:PRK14246    6 SAEDVF-NISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIeIYDSkikvdGKVLYFGKDIFQiD 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  75 SREIKRRVGYMTQRFTYWEDLTVRENLDFVARLYEVRRRRERVDRMLDELR-------LGSRAKQLAGSLSGGWKQRLAL 147
Cdd:PRK14246   85 AIKLRKEVGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRkvglwkeVYDRLNSPASQLSGGQQQRLTI 164
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 148 AAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDL 222
Cdd:PRK14246  165 ARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEI 239
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
20-194 3.48e-07

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 51.59  E-value: 3.48e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  20 RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDS-GHGTCL--GYDITKqsREIKRRVGYMTQRFTYWEDLT 96
Cdd:TIGR00955  38 KHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVkGSGSVLlnGMPIDA--KEMRAISAYVQQDDLFIPTLT 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  97 VRENLDFVARL-----YEVRRRRERVDRMLDELRLGSRAKQLAG------SLSGGWKQRLALAAALLQEPELLLLDEPTA 165
Cdd:TIGR00955 116 VREHLMFQAHLrmprrVTKKEKRERVDEVLQALGLRKCANTRIGvpgrvkGLSGGERKRLAFASELLTDPPLLFCDEPTS 195
                         170       180
                  ....*....|....*....|....*....
gi 1422354951 166 GVDPSARREFWEELHRLAARGISVLVSTH 194
Cdd:TIGR00955 196 GLDSFMAYSVVQVLKGLAQKGKTIICTIH 224
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
7-101 3.52e-07

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 51.36  E-value: 3.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTpdsgHGTCLGyDITKQSREIKRR----- 81
Cdd:TIGR02633   1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYP----HGTWDG-EIYWSGSPLKASnirdt 75
                          90       100
                  ....*....|....*....|....
gi 1422354951  82 ----VGYMTQRFTYWEDLTVRENL 101
Cdd:TIGR02633  76 eragIVIIHQELTLVPELSVAENI 99
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
3-205 4.85e-07

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 50.75  E-value: 4.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   3 ADDLLIDVHRLNKRFGDR-HVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE-IKR 80
Cdd:TIGR02857 317 APASSLEFSGVSVAYPGRrPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADsWRD 396
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  81 RVGYMTQRFTYWEDlTVRENLDF------------VARLYEVRRRRERVDRMLDeLRLGSRAkqlAGsLSGGWKQRLALA 148
Cdd:TIGR02857 397 QIAWVPQHPFLFAG-TIAENIRLarpdasdaeireALERAGLDEFVAALPQGLD-TPIGEGG---AG-LSGGQAQRLALA 470
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951 149 AALLQEPELLLLDEPTAGVDPSARREFWEELHRLaARGISVLVSTHYMDEAERCHKL 205
Cdd:TIGR02857 471 RAFLRDAPLLLLDEPTAHLDAETEAEVLEALRAL-AQGRTVLLVTHRLALAALADRI 526
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
4-238 9.86e-07

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 49.46  E-value: 9.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   4 DDLLIDVHRLNKRFGD-RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH----GTCLGYDiTKQSREI 78
Cdd:PRK13636    2 EDYILKVEELNYNYSDgTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRilfdGKPIDYS-RKGLMKL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  79 KRRVGYMTQRftywedltvRENLDFVARLYEVRRRRERVDRM-LDELRLG-SRAKQLAG----------SLSGGWKQRLA 146
Cdd:PRK13636   81 RESVGMVFQD---------PDNQLFSASVYQDVSFGAVNLKLpEDEVRKRvDNALKRTGiehlkdkpthCLSFGQKKRVA 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 147 LAAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDE-AERCHKLAYISYGVLLAQGEARDLIR 224
Cdd:PRK13636  152 IAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKElGLTIIIATHDIDIvPLYCDNVFVMKEGRVILQGNPKEVFA 231
                         250
                  ....*....|....
gi 1422354951 225 QQALhtwaVSGANL 238
Cdd:PRK13636  232 EKEM----LRKVNL 241
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
19-226 1.07e-06

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 50.11  E-value: 1.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  19 DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK-QSREIKRRVGYMTQRFTYWEDlTV 97
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQyDHHYLHRQVALVGQEPVLFSG-SV 571
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDFVARLYEVRRRRERVDR-------MLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPS 170
Cdd:TIGR00958 572 RENIAYGLTDTPDEEIMAAAKAanahdfiMEFPNGYDTEVGEKGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAE 651
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1422354951 171 ARREFWEELHRlaaRGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQ 226
Cdd:TIGR00958 652 CEQLLQESRSR---ASRTVLLIAHRLSTVERADQILVLKKGSVVEMGTHKQLMEDQ 704
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
20-191 1.38e-06

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 49.25  E-value: 1.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  20 RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE--IKRRVGYMTqrftywED--- 94
Cdd:COG3845   271 VPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRerRRLGVAYIP------EDrlg 344
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  95 ------LTVRENLdfVARLYEVRRRRERVdrMLDELRLGSRAKQL--------------AGSLSGGWKQRlalaaallqe 154
Cdd:COG3845   345 rglvpdMSVAENL--ILGRYRRPPFSRGG--FLDRKAIRAFAEELieefdvrtpgpdtpARSLSGGNQQKvilarelsrd 420
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1422354951 155 pelllldepTAGVDPSARREFWEELHRLAARGISVLV 191
Cdd:COG3845   421 pklliaaqpTRGLDVGAIEFIHQRLLELRDAGAAVLL 457
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
22-199 1.45e-06

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 48.93  E-value: 1.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  22 VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG--------------HGTCLGYDIT-----------KQSR 76
Cdd:PRK13651   22 ALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGtiewifkdeknkkkTKEKEKVLEKlviqktrfkkiKKIK 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  77 EIKRRVGYMTQRFTY--WEDlTVRENLDFVARLYEVRRRRERVDRM-------LDELRLgsraKQLAGSLSGGWKQRLAL 147
Cdd:PRK13651  102 EIRRRVGVVFQFAEYqlFEQ-TIEKDIIFGPVSMGVSKEEAKKRAAkyielvgLDESYL----QRSPFELSGGQKRRVAL 176
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 148 AAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEA 199
Cdd:PRK13651  177 AGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNV 228
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
1-63 1.70e-06

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 49.30  E-value: 1.70e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951   1 MNADDLLiDVHRLNKRFGD----RHVVKDLSMQVRRGEIFGFLGPNGSGKT-TSMRMMcGLLTPDSGH 63
Cdd:COG4172     1 MMSMPLL-SVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvTALSIL-RLLPDPAAH 66
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
15-101 1.97e-06

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 49.16  E-value: 1.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  15 KRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLtPdsgHGTCLGyDI-----TKQSREIK--RRVG--YM 85
Cdd:PRK13549   13 KTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVY-P---HGTYEG-EIifegeELQASNIRdtERAGiaII 87
                          90
                  ....*....|....*.
gi 1422354951  86 TQRFTYWEDLTVRENL 101
Cdd:PRK13549   88 HQELALVKELSVLENI 103
ycf16 CHL00131
sulfate ABC transporter protein; Validated
1-55 2.06e-06

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 48.10  E-value: 2.06e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951   1 MNADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCG 55
Cdd:CHL00131    1 MNKNKPILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG 55
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
19-230 2.26e-06

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 48.94  E-value: 2.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  19 DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMTQRFTYWEDlTV 97
Cdd:TIGR02203 344 DRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTlASLRRQVALVSQDVVLFND-TI 422
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDFVARLYEVRRRRERVDRM------LDELRLG--SRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDP 169
Cdd:TIGR02203 423 ANNIAYGRTEQADRAEIERALAAayaqdfVDKLPLGldTPIGENGVLLSGGQRQRLAIARALLKDAPILILDEATSALDN 502
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 170 SARREFWEELHRLaARGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQALHT 230
Cdd:TIGR02203 503 ESERLVQAALERL-MQGRTTLVIAHRLSTIEKADRIVVMDDGRIVERGTHNELLARNGLYA 562
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
10-144 3.43e-06

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 47.36  E-value: 3.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  10 VHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH---GTCLGYDITKQSReikrrvgYMT 86
Cdd:PRK11247   15 LNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGEllaGTAPLAEAREDTR-------LMF 87
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 Q--RFTYWEdlTVRENLDfvarLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:PRK11247   88 QdaRLLPWK--KVIDNVG----LGLKGQWRDAALQALAAVGLADRANEWPAALSGGQKQR 141
cbiO PRK13642
energy-coupling factor transporter ATPase;
19-222 3.55e-06

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 47.78  E-value: 3.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  19 DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSR-EIKRRVGYMTQR-FTYWEDLT 96
Cdd:PRK13642   19 DVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVwNLRRKIGMVFQNpDNQFVGAT 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  97 VRENLDFvaRLYEVRRRRERVDRMLDELRLGSRAKQLA----GSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSAR 172
Cdd:PRK13642   99 VEDDVAF--GMENQGIPREEMIKRVDEALLAVNMLDFKtrepARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGR 176
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 173 REFWEELHRLAAR-GISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDL 222
Cdd:PRK13642  177 QEIMRVIHEIKEKyQLTVLSITHDLDEAASSDRILVMKAGEIIKEAAPSEL 227
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
7-196 4.83e-06

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 46.91  E-value: 4.83e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyDITKQSREIKRRVGYMT 86
Cdd:PRK11300    5 LLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGG-------TILLRGQHIEGLPGHQI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  87 QRF----TY-----WEDLTVRENL----------DFVARLY-------EVRRRRERVDRMLDELRLGSRAKQLAGSLSGG 140
Cdd:PRK11300   78 ARMgvvrTFqhvrlFREMTVIENLlvaqhqqlktGLFSGLLktpafrrAESEALDRAATWLERVGLLEHANRQAGNLAYG 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951 141 WKQRLALAAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYM 196
Cdd:PRK11300  158 QQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHDM 214
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
11-216 1.04e-05

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 45.95  E-value: 1.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  11 HRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRV-------- 82
Cdd:TIGR02769  15 GGLFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDRKQRRAFrrdvqlvf 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 --------GYMTQRFTYWEDLTVRENLDFVARLyevrrrrERVDRMLDELRLGSR-AKQLAGSLSGGWKQRLALAAALLQ 153
Cdd:TIGR02769  95 qdspsavnPRMTVRQIIGEPLRHLTSLDESEQK-------ARIAELLDMVGLRSEdADKLPRQLSGGQLQRINIARALAV 167
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951 154 EPELLLLDEPTAGVDPSARREFWEELHRLAAR-GISVLVSTHYMDEAER-CHKLAYISYGVLLAQ 216
Cdd:TIGR02769 168 KPKLIVLDEAVSNLDMVLQAVILELLRKLQQAfGTAYLFITHDLRLVQSfCQRVAVMDKGQIVEE 232
cbiO PRK13645
energy-coupling factor transporter ATPase;
27-201 1.41e-05

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 45.77  E-value: 1.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  27 SMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDI------TKQSREIKRRVGYMTQ--RFTYWEDlTVR 98
Cdd:PRK13645   31 SLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIpanlkkIKEVKRLRKEIGLVFQfpEYQLFQE-TIE 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  99 ENLDF--VARLYEVRRRRERVDRMLDELRLGSR-AKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREF 175
Cdd:PRK13645  110 KDIAFgpVNLGENKQEAYKKVPELLKLVQLPEDyVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDF 189
                         170       180
                  ....*....|....*....|....*..
gi 1422354951 176 WEELHRL-AARGISVLVSTHYMDEAER 201
Cdd:PRK13645  190 INLFERLnKEYKKRIIMVTHNMDQVLR 216
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
18-48 1.42e-05

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 45.21  E-value: 1.42e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTT 48
Cdd:cd03217    11 GGKEILKGVNLTIKKGEVHALMGPNGSGKST 41
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
27-191 1.60e-05

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 46.06  E-value: 1.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  27 SMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVGYMTQRftywED---------LTV 97
Cdd:PRK11288  273 SFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRAGIMLCP----EDrkaegiipvHSV 348
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDFVAR--------LYEVRRRRERVDRMLDELRLGSR-AKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVD 168
Cdd:PRK11288  349 ADNINISARrhhlragcLINNRWEAENADRFIRSLNIKTPsREQLIMNLSGGNQQKAILGRWLSEDMKVILLDEPTRGID 428
                         170       180
                  ....*....|....*....|...
gi 1422354951 169 PSARREFWEELHRLAARGISVLV 191
Cdd:PRK11288  429 VGAKHEIYNVIYELAAQGVAVLF 451
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
19-144 1.74e-05

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 45.30  E-value: 1.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  19 DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMTQRfTYWEDLTV 97
Cdd:cd03251    14 GPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTlASLRRQIGLVSQD-VFLFNDTV 92
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951  98 RENLDF------------VARLYEVRRRRERVDRMLDElRLGSRAkqlaGSLSGGWKQR 144
Cdd:cd03251    93 AENIAYgrpgatreeveeAARAANAHEFIMELPEGYDT-VIGERG----VKLSGGQRQR 146
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
23-226 2.81e-05

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 44.74  E-value: 2.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMTQ----RFTyweDLTV 97
Cdd:PRK13648   25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNfEKLRKHIGIVFQnpdnQFV---GSIV 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDF--VARLYEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREF 175
Cdd:PRK13648  102 KYDVAFglENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNL 181
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1422354951 176 WEELHRLAA-RGISVLVSTHYMDEAERCHKLAYISYGVLLAQGEARDLIRQQ 226
Cdd:PRK13648  182 LDLVRKVKSeHNITIISITHDLSEAMEADHVIVMNKGTVYKEGTPTEIFDHA 233
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
1-144 4.23e-05

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 44.34  E-value: 4.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNADDLLIDVHRLNKRF---------GDRHV--VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGY 69
Cdd:COG4608     1 AAMAEPLLEVRDLKKHFpvrgglfgrTVGVVkaVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  70 DITKQS----REIKRRVGYMTQ--------RFTYWEdlTVRENLDfVARLYEVRRRRERVDRMLDELRLGSR-AKQLAGS 136
Cdd:COG4608    81 DITGLSgrelRPLRRRMQMVFQdpyaslnpRMTVGD--IIAEPLR-IHGLASKAERRERVAELLELVGLRPEhADRYPHE 157

                  ....*...
gi 1422354951 137 LSGGWKQR 144
Cdd:COG4608   158 FSGGQRQR 165
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
5-62 4.45e-05

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 44.04  E-value: 4.45e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951   5 DLLIDVHRlNKRFgdrHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:PRK13546   26 DALIPKHK-NKTF---FALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVG 79
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
5-62 5.32e-05

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 44.01  E-value: 5.32e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951   5 DLLIDVHRLNKRFGDR-------HV--VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:PRK15112    2 ETLLEVRNLSKTFRYRtgwfrrqTVeaVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSG 68
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
4-218 5.43e-05

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 44.07  E-value: 5.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   4 DDLLIDVHRLNKRFGDRH-----VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG-----------HGTCL 67
Cdd:PRK13631   18 DDIILRVKNLYCVFDEKQenelvALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGtiqvgdiyigdKKNNH 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  68 GYDITKQSREIK------RRVGYMTQ--RFTYWEDlTVRENLDF--VARLYEVRRRRERVDRMLDELRLGSRAKQLAG-S 136
Cdd:PRK13631   98 ELITNPYSKKIKnfkelrRRVSMVFQfpEYQLFKD-TIEKDIMFgpVALGVKKSEAKKLAKFYLNKMGLDDSYLERSPfG 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 137 LSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDeaercHKLAYISYGVLLAQ 216
Cdd:PRK13631  177 LSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTME-----HVLEVADEVIVMDK 251

                  ..
gi 1422354951 217 GE 218
Cdd:PRK13631  252 GK 253
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
18-144 5.46e-05

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 44.57  E-value: 5.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRR-VGYMTQR---Ftywe 93
Cdd:PRK13657  346 NSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRRnIAVVFQDaglF---- 421
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951  94 DLTVRENL----------------------DFVARlyevrrrrervdrmlDELRLGSRAKQLAGSLSGGWKQR 144
Cdd:PRK13657  422 NRSIEDNIrvgrpdatdeemraaaeraqahDFIER---------------KPDGYDTVVGERGRQLSGGERQR 479
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
18-107 6.37e-05

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 44.71  E-value: 6.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSM-----RMMCGLLTPD----SGHGTclgyDITKQsreikRRVGYMTQR 88
Cdd:TIGR00956  774 EKRVILNNVDGWVKPGTLTALMGASGAGKTTLLnvlaeRVTTGVITGGdrlvNGRPL----DSSFQ-----RSIGYVQQQ 844
                           90
                   ....*....|....*....
gi 1422354951   89 FTYWEDLTVRENLDFVARL 107
Cdd:TIGR00956  845 DLHLPTSTVRESLRFSAYL 863
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
30-95 6.46e-05

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 44.41  E-value: 6.46e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951  30 VRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDsghgtcLGYDITKQSRE--IKRRVGymTQRFTYWEDL 95
Cdd:PRK13409   96 PKEGKVTGILGPNGIGKTTAVKILSGELIPN------LGDYEEEPSWDevLKRFRG--TELQNYFKKL 155
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
31-62 7.45e-05

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 44.00  E-value: 7.45e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1422354951  31 RRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:COG1245    97 KKGKVTGILGPNGIGKSTALKILSGELKPNLG 128
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
19-144 8.37e-05

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 43.30  E-value: 8.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  19 DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQS-REIKRRVGYMTQR---FtyweD 94
Cdd:cd03249    15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNlRWLRSQIGLVSQEpvlF----D 90
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951  95 LTVRENLDF------------VARLYEVRRRRERVDRMLDELrLGSRAKQLagslSGGWKQR 144
Cdd:cd03249    91 GTIAENIRYgkpdatdeeveeAAKKANIHDFIMSLPDGYDTL-VGERGSQL----SGGQKQR 147
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
18-169 8.49e-05

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 42.98  E-value: 8.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKR-RVGYMTQRFTYWEDlT 96
Cdd:cd03254    14 EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRsMIGVVLQDTFLFSG-T 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  97 VRENLDFvARLYEVRRRRERVDRMLDELRLGSR--------AKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVD 168
Cdd:cd03254    93 IMENIRL-GRPNATDEEVIEAAKEAGAHDFIMKlpngydtvLGENGGNLSQGERQLLAIARAMLRDPKILILDEATSNID 171

                  .
gi 1422354951 169 P 169
Cdd:cd03254   172 T 172
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
18-107 1.36e-04

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 41.85  E-value: 1.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCL--GYDITKqsrEIKRRVGYMTQRFTYWEDL 95
Cdd:cd03232    18 GKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAGVITGEILinGRPLDK---NFQRSTGYVEQQDVHSPNL 94
                          90
                  ....*....|..
gi 1422354951  96 TVRENLDFVARL 107
Cdd:cd03232    95 TVREALRFSALL 106
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
14-144 2.00e-04

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  14 NKRFG---DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE-IKRRVGYMTQRF 89
Cdd:cd03253     5 NVTFAydpGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDsLRRAIGVVPQDT 84
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1422354951  90 TYWEDlTVRENLDFvARLYEVRrrrervdrmlDELRLGSRAKQLAGS------------------LSGGWKQR 144
Cdd:cd03253    85 VLFND-TIGYNIRY-GRPDATD----------EEVIEAAKAAQIHDKimrfpdgydtivgerglkLSGGEKQR 145
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
17-222 2.66e-04

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 42.01  E-value: 2.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  17 FGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH---GTCL--GYDI--TKQSREIKRRVGYMTQRF 89
Cdd:PRK14271   31 FAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYrysGDVLlgGRSIfnYRDVLEFRRRVGMLFQRP 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  90 TYWEdLTVRENLDFVAR---LYEVRRRRERVDRMLDELRLGSRAK-QLAGS---LSGGWKQRLALAAALLQEPELLLLDE 162
Cdd:PRK14271  111 NPFP-MSIMDNVLAGVRahkLVPRKEFRGVAQARLTEVGLWDAVKdRLSDSpfrLSGGQQQLLCLARTLAVNPEVLLLDE 189
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1422354951 163 PTAGVDPSARREFWEELHRLAARgISVLVSTHYMDEAERCHKLAYISY-GVLLAQGEARDL 222
Cdd:PRK14271  190 PTSALDPTTTEKIEEFIRSLADR-LTVIIVTHNLAQAARISDRAALFFdGRLVEEGPTEQL 249
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
20-62 2.71e-04

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 41.48  E-value: 2.71e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1422354951  20 RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLL--TPDSG 62
Cdd:COG2401    43 RYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAG 87
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
22-56 2.86e-04

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 40.60  E-value: 2.86e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1422354951  22 VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGL 56
Cdd:cd03223    16 LLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGL 50
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
32-62 2.99e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 40.43  E-value: 2.99e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1422354951   32 RGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGG 31
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
7-232 3.04e-04

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 41.96  E-value: 3.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRF----GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTP---DSGHGTCLGYDITKQS-REI 78
Cdd:COG0444     1 LLEVRNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKLSeKEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  79 K----RRVGYMTQrftyweD--------LTVRENLDFVARLYEVRRRRERV---DRMLDELRL---GSRAKQLAGSLSGG 140
Cdd:COG0444    81 RkirgREIQMIFQ------DpmtslnpvMTVGDQIAEPLRIHGGLSKAEAReraIELLERVGLpdpERRLDRYPHELSGG 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 141 WKQRlalaaallqepelllLDEPTAGVDPSARREFWEELHRLAA-RGISVLVSTHYMDE-AERCHKLAyisygVLLA--- 215
Cdd:COG0444   155 MRQRvmiaralalepklliADEPTTALDVTIQAQILNLLKDLQReLGLAILFITHDLGVvAEIADRVA-----VMYAgri 229
                         250       260
                  ....*....|....*....|.
gi 1422354951 216 --QGEARDLIRqQALH--TWA 232
Cdd:COG0444   230 veEGPVEELFE-NPRHpyTRA 249
sufC TIGR01978
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ...
13-195 3.07e-04

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273907 [Multi-domain]  Cd Length: 243  Bit Score: 41.48  E-value: 3.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  13 LNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGllTPD----SGHGTCLGYDITKQSREIKRRVGyMTQR 88
Cdd:TIGR01978   6 LHVSVEDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAG--HPSyevtSGTILFKGQDLLELEPDERARAG-LFLA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  89 FTYWEDLTVRENLDFV-----ARLYEVRRRRERVDRMLDELRLGSRAKQLAGSL---------SGGWKQRLALAAALLQE 154
Cdd:TIGR01978  83 FQYPEEIPGVSNLEFLrsalnARRSARGEEPLDLLDFEKLLKEKLALLDMDEEFlnrsvnegfSGGEKKRNEILQMALLE 162
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1422354951 155 PELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHY 195
Cdd:TIGR01978 163 PKLAILDEIDSGLDIDALKIVAEGINRLREPDRSFLIITHY 203
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
18-48 3.15e-04

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 41.59  E-value: 3.15e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTT 48
Cdd:COG0396    11 EGKEILKGVNLTIKPGEVHAIMGPNGSGKST 41
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
25-101 3.25e-04

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 42.21  E-value: 3.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  25 DLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG----HGTCLGYDITKQSreIKRRVGYMTQRFTYWEDLTVREN 100
Cdd:PRK11288   22 DISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGsiliDGQEMRFASTTAA--LAAGVAIIYQELHLVPEMTVAEN 99

                  .
gi 1422354951 101 L 101
Cdd:PRK11288  100 L 100
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
18-63 3.76e-04

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 41.75  E-value: 3.76e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH 63
Cdd:PRK11650   15 GKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGE 60
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
15-199 3.86e-04

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 41.55  E-value: 3.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  15 KRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH---GTCLGYDITKQsreiKRRVGYMTQRFTY 91
Cdd:PRK11000   11 KAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDlfiGEKRMNDVPPA----ERGVGMVFQSYAL 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  92 WEDLTVRENLDFVARLYEVRRRRERV--DRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDP 169
Cdd:PRK11000   87 YPHLSVAENMSFGLKLAGAKKEEINQrvNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDA 166
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1422354951 170 SARREFWEELHRLAAR-GISVLVSTHYMDEA 199
Cdd:PRK11000  167 ALRVQMRIEISRLHKRlGRTMIYVTHDQVEA 197
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
3-84 4.51e-04

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 41.54  E-value: 4.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   3 ADDLLIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTsmrmMCGLLTPDsgHGTCLGYDITKQSR------ 76
Cdd:PRK10938  256 ANEPRIVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKST----LLSLITGD--HPQGYSNDLTLFGRrrgsge 329
                          90
                  ....*....|.
gi 1422354951  77 ---EIKRRVGY 84
Cdd:PRK10938  330 tiwDIKKHIGY 340
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
19-213 4.62e-04

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 40.92  E-value: 4.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  19 DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITK-QSREIKRRVGYMTQRFTYWEDlTV 97
Cdd:cd03248    26 DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQyEHKYLHSKVSLVGQEPVLFAR-SL 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDF-----VARLYEVRRRRERVDRMLDELRLG--SRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPS 170
Cdd:cd03248   105 QDNIAYglqscSFECVKEAAQKAHAHSFISELASGydTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAE 184
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1422354951 171 ARREFwEELHRLAARGISVLVSTHYMDEAERCHKLAYISYGVL 213
Cdd:cd03248   185 SEQQV-QQALYDWPERRTVLVIAHRLSTVERADQILVLDGGRI 226
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
23-193 4.63e-04

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 41.53  E-value: 4.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSRE--IKRRVGYMTqrftywED------ 94
Cdd:PRK10762  268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQdgLANGIVYIS------EDrkrdgl 341
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  95 ---LTVREN-----LDFVARLYEVRRRRERVDRMLDELRL-----GSRaKQLAGSLSGGWKQRLALAAALLQEPELLLLD 161
Cdd:PRK10762  342 vlgMSVKENmsltaLRYFSRAGGSLKHADEQQAVSDFIRLfniktPSM-EQAIGLLSGGNQQKVAIARGLMTRPKVLILD 420
                         170       180       190
                  ....*....|....*....|....*....|...
gi 1422354951 162 EPTAGVDPSARREFWEELHRLAARGIS-VLVST 193
Cdd:PRK10762  421 EPTRGVDVGAKKEIYQLINQFKAEGLSiILVSS 453
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
20-224 4.67e-04

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 41.16  E-value: 4.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  20 RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT-----KQSREIKRRVGYMtqrFTYWE- 93
Cdd:PRK13634   20 RRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITagkknKKLKPLRKKVGIV---FQFPEh 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  94 ---DLTVRENLDF------VARlyevRRRRERVDRMLDELRLGsrAKQLAGS---LSGGWKQRLALAAALLQEPELLLLD 161
Cdd:PRK13634   97 qlfEETVEKDICFgpmnfgVSE----EDAKQKAREMIELVGLP--EELLARSpfeLSGGQMRRVAIAGVLAMEPEVLVLD 170
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951 162 EPTAGVDPSARREFWE---ELHRlaARGISVLVSTHYMDEAER-CHKLAYISYGVLLAQGEARDLIR 224
Cdd:PRK13634  171 EPTAGLDPKGRKEMMEmfyKLHK--EKGLTTVLVTHSMEDAARyADQIVVMHKGTVFLQGTPREIFA 235
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
13-49 5.75e-04

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 41.23  E-value: 5.75e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1422354951  13 LNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTS 49
Cdd:PRK15134  292 LKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTT 328
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
18-199 6.38e-04

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 40.62  E-value: 6.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  18 GDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREikRRVGYMTQRFTYWedLTV 97
Cdd:COG4525    18 QPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGAD--RGVVFQKDALLPW--LNV 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  98 RENLDFVARL--YEVRRRRERVDRMLDELRLGSRAKQLAGSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREF 175
Cdd:COG4525    94 LDNVAFGLRLrgVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGALDALTREQM 173
                         170       180
                  ....*....|....*....|....*
gi 1422354951 176 WEELHRLAAR-GISVLVSTHYMDEA 199
Cdd:COG4525   174 QELLLDVWQRtGKGVFLITHSVEEA 198
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
30-62 6.42e-04

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 40.43  E-value: 6.42e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1422354951  30 VRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:cd03236    23 PREGQVLGLVGPNGIGKSTALKILAGKLKPNLG 55
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
8-218 6.68e-04

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 40.45  E-value: 6.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   8 IDVHRLNKRFG-----DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREikRRV 82
Cdd:COG1101     2 LELKNLSKTFNpgtvnEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEY--KRA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  83 GYMTQRF------TYwEDLTVRENLDFVA--------RLYEVRRRRERVDRMLDELRLG--SRAKQLAGSLSGGwkQRla 146
Cdd:COG1101    80 KYIGRVFqdpmmgTA-PSMTIEENLALAYrrgkrrglRRGLTKKRRELFRELLATLGLGleNRLDTKVGLLSGG--QRqa 156
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1422354951 147 laaall--qepellllDEPTAGVDPsARREFWEEL-HRLAAR-GISVLVSTHYMDEAerchklayISYG---VLLAQGE 218
Cdd:COG1101   157 lsllmatltkpkllllDEHTAALDP-KTAALVLELtEKIVEEnNLTTLMVTHNMEQA--------LDYGnrlIMMHEGR 226
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
25-108 6.96e-04

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 39.85  E-value: 6.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  25 DLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHgtcLGYDITKQSREIKRRVGYMTQRFTYWEDLTVRENLDFV 104
Cdd:PRK13541   18 DLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGN---IYYKNCNINNIAKPYCTYIGHNLGLKLEMTVFENLKFW 94

                  ....
gi 1422354951 105 ARLY 108
Cdd:PRK13541   95 SEIY 98
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
23-143 7.53e-04

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 40.76  E-value: 7.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLS---MQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT----KQSREIKrrVGYMTQRFTYWEDL 95
Cdd:PRK10762   17 VKALSgaaLNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTfngpKSSQEAG--IGIIHQELNLIPQL 94
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951  96 TVRENLdFVARLYEVRRRRERVDRMLDEL-----RLGSR--AKQLAGSLSGGWKQ 143
Cdd:PRK10762   95 TIAENI-FLGREFVNRFGRIDWKKMYAEAdkllaRLNLRfsSDKLVGELSIGEQQ 148
cbiO PRK13646
energy-coupling factor transporter ATPase;
23-253 8.14e-04

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 40.53  E-value: 8.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDIT-----KQSREIKRRVGYM-----TQRFtyw 92
Cdd:PRK13646   23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITIThktkdKYIRPVRKRIGMVfqfpeSQLF--- 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  93 EDLTVRE----------NLDFV-ARLYEvrrrrervdrMLDELRLGSRAKQLAG-SLSGGWKQRLALAAALLQEPELLLL 160
Cdd:PRK13646  100 EDTVEREiifgpknfkmNLDEVkNYAHR----------LLMDLGFSRDVMSQSPfQMSGGQMRKIAIVSILAMNPDIIVL 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951 161 DEPTAGVDPSARREFWEELHRLAA-RGISVLVSTHYMDE-AERCHKLAYISYGVLLAQGEARDLIRQ-QALHTWAvsgan 237
Cdd:PRK13646  170 DEPTAGLDPQSKRQVMRLLKSLQTdENKTIILVSHDMNEvARYADEVIVMKEGSIVSQTSPKELFKDkKKLADWH----- 244
                         250
                  ....*....|....*.
gi 1422354951 238 lVGLNDRLQGQPGVEQ 253
Cdd:PRK13646  245 -IGLPEIVQLQYDFEQ 259
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
24-201 9.40e-04

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 40.80  E-value: 9.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  24 KDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRRVG-------------------- 83
Cdd:PRK15439  280 RNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRLARGlvylpedrqssglyldapla 359
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  84 -----YMTQRFTYWEDlTVRENldfvarlyevrrrrervdRMLDELR--LG---SRAKQLAGSLSGGWKQRLALAAALLQ 153
Cdd:PRK15439  360 wnvcaLTHNRRGFWIK-PAREN------------------AVLERYRraLNikfNHAEQAARTLSGGNQQKVLIAKCLEA 420
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1422354951 154 EPELLLLDEPTAGVDPSARREFWEELHRLAARGISVLVSTHYMDEAER 201
Cdd:PRK15439  421 SPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQ 468
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
1-190 1.01e-03

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 39.72  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   1 MNAddlLIDVHRLNKRF-----GDR--HVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH------GTCL 67
Cdd:COG4778     1 MTT---LLEVENLSKTFtlhlqGGKrlPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSilvrhdGGWV 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  68 gyDITK-QSREI----KRRVGYMTQrFtywedLTVREN---LDFVA-----RLYEVRRRRERVDRMLDELRLGSRAKQLA 134
Cdd:COG4778    78 --DLAQaSPREIlalrRRTIGYVSQ-F-----LRVIPRvsaLDVVAeplleRGVDREEARARARELLARLNLPERLWDLP 149
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1422354951 135 -GSLSGGWKQRLALAAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAARGISVL 190
Cdd:COG4778   150 pATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAII 206
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
22-103 1.15e-03

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 39.84  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  22 VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgydITKQSreikRRVGYMTQrFTYWEDLTVRENL 101
Cdd:cd03291    52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEG--------KIKHS----GRISFSSQ-FSWIMPGTIKENI 118

                  ..
gi 1422354951 102 DF 103
Cdd:cd03291   119 IF 120
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
1-57 1.30e-03

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 40.09  E-value: 1.30e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1422354951   1 MNADDLLIDVHRLNKRF----GDRHVVKDLSMQVRRGEIFGFLGPNGSGKT-TSMRMMcGLL 57
Cdd:PRK09473    6 QQQADALLDVKDLRVTFstpdGDVTAVNDLNFSLRAGETLGIVGESGSGKSqTAFALM-GLL 66
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
7-201 1.35e-03

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 39.37  E-value: 1.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMM--CGLLTPD---------SGHGTclgYDITKQS 75
Cdd:PRK14239    5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLNPEvtitgsivyNGHNI---YSPRTDT 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  76 REIKRRVGYMTQR-----FTYWEDLTVRENLDFV---ARLYEVRRRRERVDRMLDELRlgSRAKQLAGSLSGGWKQRLAL 147
Cdd:PRK14239   82 VDLRKEIGMVFQQpnpfpMSIYENVVYGLRLKGIkdkQVLDEAVEKSLKGASIWDEVK--DRLHDSALGLSGGQQQRVCI 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1422354951 148 AAALLQEPELLLLDEPTAGVDPSARREFWEELHRLAARgISVLVSTHYMDEAER 201
Cdd:PRK14239  160 ARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD-YTMLLVTRSMQQASR 212
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
17-104 1.41e-03

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 40.26  E-value: 1.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  17 FGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHgtclgyditkQSREIKRRVGYMTQ-RFTYwEDL 95
Cdd:PRK15064   11 FGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGN----------VSLDPNERLGKLRQdQFAF-EEF 79

                  ....*....
gi 1422354951  96 TVrenLDFV 104
Cdd:PRK15064   80 TV---LDTV 85
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
26-207 1.59e-03

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 39.78  E-value: 1.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  26 LSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGHGTCLGYDITKQSREIKRrvgymtQRFT-----YW--EDLTVR 98
Cdd:COG4615   351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADNREAYR------QLFSavfsdFHlfDRLLGL 424
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  99 ENLDFVARLyevrrrrervDRMLDELRLGSRAKQLAG-----SLSGGWKQRLALAAallqepelllldeptAGV------ 167
Cdd:COG4615   425 DGEADPARA----------RELLERLELDHKVSVEDGrfsttDLSQGQRKRLALLV---------------ALLedrpil 479
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1422354951 168 ---------DPSARREFWEE-LHRLAARGISVLVSTH---YMDEAERCHKLAY 207
Cdd:COG4615   480 vfdewaadqDPEFRRVFYTElLPELKARGKTVIAISHddrYFDLADRVLKMDY 532
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
22-144 1.70e-03

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 38.99  E-value: 1.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951  22 VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyditkqSREIKRRVGYMTQrfTYW-EDLTVREN 100
Cdd:cd03250    20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSG------------SVSVPGSIAYVSQ--EPWiQNGTIREN 85
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1422354951 101 LDFVARLyevrrrrervdrmlDELRLGS--RA-------KQLAG-----------SLSGGWKQR 144
Cdd:cd03250    86 ILFGKPF--------------DEERYEKviKAcalepdlEILPDgdlteigekgiNLSGGQKQR 135
PLN03140 PLN03140
ABC transporter G family member; Provisional
22-106 2.08e-03

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 39.83  E-value: 2.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   22 VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPD---SGHGTCLGYditKQSREIKRRV-GYMTQRFTYWEDLTV 97
Cdd:PLN03140   180 ILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAGKLDPSlkvSGEITYNGY---RLNEFVPRKTsAYISQNDVHVGVMTV 256

                   ....*....
gi 1422354951   98 RENLDFVAR 106
Cdd:PLN03140   257 KETLDFSAR 265
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
7-48 2.46e-03

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 38.62  E-value: 2.46e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTT 48
Cdd:PRK09580    1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKST 42
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
23-62 2.57e-03

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 39.18  E-value: 2.57e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1422354951  23 VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:PRK10522  339 VGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSG 378
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
22-103 3.39e-03

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 39.12  E-value: 3.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1422354951   22 VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGhgtclgyditkqsrEIKR--RVGYMTQrFTYWEDLTVRE 99
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEG--------------KIKHsgRISFSPQ-TSWIMPGTIKD 505

                   ....
gi 1422354951  100 NLDF 103
Cdd:TIGR01271  506 NIIF 509
hmuV PRK13547
heme ABC transporter ATP-binding protein;
20-72 3.89e-03

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 38.27  E-value: 3.89e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1422354951  20 RHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLT-PDSGHGTCLGYDIT 72
Cdd:PRK13547   14 RAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTgGGAPRGARVTGDVT 67
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
14-62 4.00e-03

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 38.72  E-value: 4.00e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1422354951  14 NKRFGDRH-VVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSG 62
Cdd:PRK13545   30 RSKDGEYHyALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKG 79
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
7-57 4.66e-03

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 38.18  E-value: 4.66e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1422354951   7 LIDVHRLNKRFGDRHV----VKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLL 57
Cdd:PRK11022    3 LLNVDKLSVHFGDESApfraVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLI 57
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
7-69 5.89e-03

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 38.23  E-value: 5.89e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1422354951   7 LIDVHRLNKRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTPDSGH-----GTCLGY 69
Cdd:PRK10636  312 LLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEiglakGIKLGY 379
GguA NF040905
sugar ABC transporter ATP-binding protein;
15-55 6.84e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 37.85  E-value: 6.84e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1422354951  15 KRFGDRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCG 55
Cdd:NF040905    9 KTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG 49
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
19-59 7.25e-03

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 37.37  E-value: 7.25e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1422354951  19 DRHVVKDLSMQVRRGEIFGFLGPNGSGKTTSMRMMCGLLTP 59
Cdd:PRK10418   15 AQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPA 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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