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Conserved domains on  [gi|1424145480|ref|WP_112433805|]
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ABC transporter ATP-binding protein [Thermogemmatispora tikiterensis]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467437)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including Fe(3+) ions and polyamines such as spermidine and putrescine

CATH:  3.40.50.300
EC:  7.-.-.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0005524|GO:0016887
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-365 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


:

Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 524.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMV 80
Cdd:COG3842     3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:COG3842    83 FQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRL 240
Cdd:COG3842   163 LSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLL 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 241 SARLERAVEGRCRLDGILLRVPPQPELSDGSAVLLVVRPELVTLCqlneasgaaadgggqRQGQENVLLGTVELRTFLGA 320
Cdd:COG3842   243 PGTVLGDEGGGVRTGGRTLEVPADAGLAAGGPVTVAIRPEDIRLS---------------PEGPENGLPGTVEDVVFLGS 307

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1424145480 321 VTRFRVRAAGGQLFTVDLPGLQAGTLVPGQRVRLSFPPEACLVLP 365
Cdd:COG3842   308 HVRYRVRLGDGQELVVRVPNRAALPLEPGDRVGLSWDPEDVVVLP 352
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-365 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 524.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMV 80
Cdd:COG3842     3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:COG3842    83 FQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRL 240
Cdd:COG3842   163 LSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLL 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 241 SARLERAVEGRCRLDGILLRVPPQPELSDGSAVLLVVRPELVTLCqlneasgaaadgggqRQGQENVLLGTVELRTFLGA 320
Cdd:COG3842   243 PGTVLGDEGGGVRTGGRTLEVPADAGLAAGGPVTVAIRPEDIRLS---------------PEGPENGLPGTVEDVVFLGS 307

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1424145480 321 VTRFRVRAAGGQLFTVDLPGLQAGTLVPGQRVRLSFPPEACLVLP 365
Cdd:COG3842   308 HVRYRVRLGDGQELVVRVPNRAALPLEPGDRVGLSWDPEDVVVLP 352
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 1-365 5.63e-133

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 385.16  E-value: 5.63e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMV 80
Cdd:TIGR03265   2 SPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQKRDYGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:TIGR03265  82 FQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDEP 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRL 240
Cdd:TIGR03265 162 LSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVNWL 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 241 SARleRAVEGRCRLDGILLRVPPQPELSdGSAVLLVVRPELVTLcqlneasgaaadggGQRQGQENVLLGTVELRTFLGA 320
Cdd:TIGR03265 242 PGT--RGGGSRARVGGLTLACAPGLAQP-GASVRLAVRPEDIRV--------------SPAGNAANLLLARVEDMEFLGA 304

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 1424145480 321 VTRFRVRAAG--GQLFTVDLP--GLQAGTLVPGQRVRLSFPPEACLVLP 365
Cdd:TIGR03265 305 FYRLRLRLEGlpGQALVADVSasEVERLGIRAGQPIWIELPAERLRAFA 353
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 4-235 1.19e-129

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 371.95  E-value: 1.19e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:cd03300     1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:cd03300    81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVG 235
Cdd:cd03300   161 LDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
4-368 8.68e-126

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 367.74  E-value: 8.68e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:PRK09452   15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHVNTVFQS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:PRK09452   95 YALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSA 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSAR 243
Cdd:PRK09452  175 LDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEINIFDAT 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 244 -LERAVEGRCR--LDGILLRVPPQPELSDGSAVLLVVRPELVTLCQLNEASgaaadgggqrqgQENVLLGTVELRTFLGA 320
Cdd:PRK09452  255 vIERLDEQRVRanVEGRECNIYVNFAVEPGQKLHVLLRPEDLRVEEINDDE------------HAEGLIGYVRERNYKGM 322

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 321 VTRFRVRAAGGQL------FTVDLPGLQAGtlvPGQRVRLSFPPEACLVLPLEE 368
Cdd:PRK09452  323 TLDSVVELENGKMvmvsefFNEDDPDFDHS---LGQKVAVTWVEGWEVVLADEE 373
ABC_arch_GlcV NF040933
glucose ABC transporter ATP-binding protein GlcV;
6-348 1.91e-97

glucose ABC transporter ATP-binding protein GlcV;


Pssm-ID: 468866 [Multi-domain]  Cd Length: 357  Bit Score: 294.60  E-value: 1.91e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   6 LQELTKSFGK----TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-----PANRRP 76
Cdd:NF040933    5 VENVTKIFKKgkkeVVALDNVNLEIKSGEFFGILGPSGHGKTTFLRIIAGLEVPTDGEIYFDDKLVASPgkiivPPEDRN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  77 MGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLL 156
Cdd:NF040933   85 IGMVFQNWALYPNMTVFDNIAFPLKIKKVPKDEIEKKVKEVAEILGISEVLDRYPRELSGGQQQRVALARALVKNPQVLL 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 157 LDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGA 236
Cdd:NF040933  165 LDEPFSNLDARIRDSARALVKKIQRELKITTIIVSHDPADIFSLADRAGVINNGKFQQVGKPEEIYDNPANIFVARLIGD 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 237 STRLSARleraVEGRCRLDGILLRVPPQPELSDGSAVLLVVRPELVTLcqlneasgaaaDGGGQRQGQENVLLG--TVEL 314
Cdd:NF040933  245 INLLEGK----VEEEGLVDGNDLKIPLPNPKLEAGEVIIGIRPEDIDI-----------SESDMRLPPGFVEVGkgRVKV 309

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1424145480 315 RTFLGAVTRFRVRAAGG---QLFTVDLPGLQAGTLVP 348
Cdd:NF040933  310 SSYAGGVFRVVVSPIDDdsiEIIVNSDRPIEEGEEVN 346
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
4-284 9.43e-89

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 272.33  E-value: 9.43e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFgKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:NF040840    2 IRIENLSKDW-KEFKLRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:NF040840   81 YMLFPHKTVFENIAFGLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSAR 243
Cdd:NF040840  161 LDVQTRDELIREMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFENIIEGV 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1424145480 244 LERAVEGR-CRLDGILLRVPPQPElsdgSAVLLVVRPELVTL 284
Cdd:NF040840  241 AEKGGEGTiLDTGNIKIELPEEKK----GKVRIGIRPEDITI 278
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
9-212 3.26e-50

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 168.36  E-value: 3.26e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   9 LTKSFgKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-----RPANRRPM-GMVFQ 82
Cdd:NF038007   12 ITKTI-KTKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNlsysqKIILRRELiGYIFQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:NF038007   91 SFNLIPHLSIFDNVALPLKYRGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLADEPTG 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQlGMTVIYVTHdQEEALAISGRIAVMARGRL 212
Cdd:NF038007  171 NLDSKNARAVLQQLKYINQK-GTTIIMVTH-SDEASTYGNRIINMKDGKL 218
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-162 1.07e-48

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 162.05  E-value: 1.07e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  19 VERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMVFQSYALFPHMTAEQNV 96
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTddERKSLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  97 AFGLRLRRLPPALIRQRCEELLALVGL----AERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLgdlaDRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
12-199 4.25e-27

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 106.55  E-value: 4.25e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  12 SFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeeitTRPANRRPmGMVFQSYAL---FP 88
Cdd:NF040873    1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV--------RRAGGARV-AYVPQRSEVpdsLP 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  89 hMTAEQNVAFGL----RLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSAL 164
Cdd:NF040873   72 -LTVRDLVAMGRwarrGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGL 150

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1424145480 165 DAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALA 199
Cdd:NF040873  151 DAESRERIIALLAEEHAR-GATVVVVTHDLELVRR 184
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
5-224 1.07e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 103.28  E-value: 1.07e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP-ANRRPMGMVFQS 83
Cdd:NF033858  268 EARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGDiATRRRVGYMSQA 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:NF033858  348 FSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSG 427

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 164 LDAAVR-------VTL-REEirriqqqlGMTVIYVTHDQEEAlAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:NF033858  428 VDPVARdmfwrllIELsRED--------GVTIFISTHFMNEA-ERCDRISLMHAGRVLASDTPAALVAA 487
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
4-221 5.98e-18

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 84.40  E-value: 5.98e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVlRLVAGFEQPDAGHillDQEEITTRPANRRPMGMVFQS 83
Cdd:NF000106   14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGR---RPWRF*TWCANRRALRRTIG* 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 Y-----ALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:NF000106   90 Hrpvr*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLD 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:NF000106  170 EPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
GguA NF040905
sugar ABC transporter ATP-binding protein;
4-211 9.75e-18

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 84.84  E-value: 9.75e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAG------FEqpdaGHILLDQEEI---TTRPANR 74
Cdd:NF040905    2 LEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyphgsYE----GEILFDGEVCrfkDIRDSEA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 RPMGMVFQSYALFPHMTAEQNVAFG-LRLRRlppALI-----RQRCEELLALVGLAERARSYPHQLSGGQQQRVALARAL 148
Cdd:NF040905   78 LGIVIIHQELALIPYLSIAENIFLGnERAKR---GVIdwnetNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKAL 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 149 AVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:NF040905  155 SKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGR 216
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
5-224 2.33e-15

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 77.86  E-value: 2.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIttrpANRRPMGMVFQSY 84
Cdd:NF033858    3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDM----ADARHRRAVCPRI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  85 A---------LFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVL 155
Cdd:NF033858   79 AympqglgknLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLL 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 156 LLDEPLSALDAAVRV---TLREEIRRiqQQLGMTVIYVTHDQEEAlaisGR---IAVMARGRLEQLGTPEEIYRR 224
Cdd:NF033858  159 ILDEPTTGVDPLSRRqfwELIDRIRA--ERPGMSVLVATAYMEEA----ERfdwLVAMDAGRVLATGTPAELLAR 227
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 28-213 2.06e-10

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 58.54  E-value: 2.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   28 RGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGH-ILLDQEEITTRPANRRPMGMVFqsyalfphmtaeqnvafglrlrrlp 106
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGvIYIDGEDILEEVLDQLLLIIVG------------------------- 55

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  107 palirqrceellalvglaerarSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIR-----RIQQ 181
Cdd:smart00382  56 ----------------------GKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrlllLLKS 113

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1424145480  182 QLGMTVIYVTHDQEEalAISGRIAVMARGRLE 213
Cdd:smart00382 114 EKNLTVILTTNDEKD--LGPALLRRRFDRRIV 143
GguA NF040905
sugar ABC transporter ATP-binding protein;
134-212 2.02e-09

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 59.03  E-value: 2.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 134 LSGGQQQRVALARALAVEPKVLLLDEPLSALDaavrVTLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARG 210
Cdd:NF040905  405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGID----VGAKYEIYTIINELaaeGKGVIVISSELPELLGMCDRIYVMNEG 480


                  ..
gi 1424145480 211 RL 212
Cdd:NF040905  481 RI 482
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-365 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 524.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMV 80
Cdd:COG3842     3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:COG3842    83 FQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRL 240
Cdd:COG3842   163 LSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLL 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 241 SARLERAVEGRCRLDGILLRVPPQPELSDGSAVLLVVRPELVTLCqlneasgaaadgggqRQGQENVLLGTVELRTFLGA 320
Cdd:COG3842   243 PGTVLGDEGGGVRTGGRTLEVPADAGLAAGGPVTVAIRPEDIRLS---------------PEGPENGLPGTVEDVVFLGS 307

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1424145480 321 VTRFRVRAAGGQLFTVDLPGLQAGTLVPGQRVRLSFPPEACLVLP 365
Cdd:COG3842   308 HVRYRVRLGDGQELVVRVPNRAALPLEPGDRVGLSWDPEDVVVLP 352
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 1-363 1.73e-151

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 432.19  E-value: 1.73e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMV 80
Cdd:COG3839     1 MASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDRNIAMV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:COG3839    81 FQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGAST-- 238
Cdd:COG3839   161 LSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGFIGSPPmn 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 239 RLSARLEravEGRCRLDGILLRVPPQPELSDGSAVLLVVRPELVTLCqlneasgaaadgggqrQGQENVLLGTVELRTFL 318
Cdd:COG3839   241 LLPGTVE---GGGVRLGGVRLPLPAALAAAAGGEVTLGIRPEHLRLA----------------DEGDGGLEATVEVVEPL 301

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1424145480 319 GAVTRFRVRaAGGQLFTVDLPGLQAgtLVPGQRVRLSFPPEACLV 363
Cdd:COG3839   302 GSETLVHVR-LGGQELVARVPGDTR--LRPGDTVRLAFDPERLHL 343
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 4-359 1.91e-136

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 393.74  E-value: 1.91e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-RPANRRPMGMVFQ 82
Cdd:COG1118     3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFTnLPPRERRVGFVFQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:COG1118    83 HYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSA 242
Cdd:COG1118   163 ALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLGCVNVLRG 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 243 RLEravEGRCRLDGIllRVPPQPELSDGSAVlLVVRPELVTLcqlneasgaaadggGQRQGQENVLLGTVELRTFLGAVT 322
Cdd:COG1118   243 RVI---GGQLEADGL--TLPVAEPLPDGPAV-AGVRPHDIEV--------------SREPEGENTFPATVARVSELGPEV 302

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1424145480 323 RFRVRAAG--GQLFTVDLPGLQAGTL--VPGQRVRLSFPPE 359
Cdd:COG1118   303 RVELKLEDgeGQPLEAEVTKEAWAELglAPGDPVYLRPRPA 343
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 1-365 5.63e-133

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 385.16  E-value: 5.63e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMV 80
Cdd:TIGR03265   2 SPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQKRDYGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:TIGR03265  82 FQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDEP 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRL 240
Cdd:TIGR03265 162 LSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVNWL 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 241 SARleRAVEGRCRLDGILLRVPPQPELSdGSAVLLVVRPELVTLcqlneasgaaadggGQRQGQENVLLGTVELRTFLGA 320
Cdd:TIGR03265 242 PGT--RGGGSRARVGGLTLACAPGLAQP-GASVRLAVRPEDIRV--------------SPAGNAANLLLARVEDMEFLGA 304

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 1424145480 321 VTRFRVRAAG--GQLFTVDLP--GLQAGTLVPGQRVRLSFPPEACLVLP 365
Cdd:TIGR03265 305 FYRLRLRLEGlpGQALVADVSasEVERLGIRAGQPIWIELPAERLRAFA 353
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 4-235 1.19e-129

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 371.95  E-value: 1.19e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:cd03300     1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:cd03300    81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVG 235
Cdd:cd03300   161 LDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
4-368 8.68e-126

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 367.74  E-value: 8.68e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:PRK09452   15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHVNTVFQS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:PRK09452   95 YALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSA 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSAR 243
Cdd:PRK09452  175 LDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEINIFDAT 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 244 -LERAVEGRCR--LDGILLRVPPQPELSDGSAVLLVVRPELVTLCQLNEASgaaadgggqrqgQENVLLGTVELRTFLGA 320
Cdd:PRK09452  255 vIERLDEQRVRanVEGRECNIYVNFAVEPGQKLHVLLRPEDLRVEEINDDE------------HAEGLIGYVRERNYKGM 322

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 321 VTRFRVRAAGGQL------FTVDLPGLQAGtlvPGQRVRLSFPPEACLVLPLEE 368
Cdd:PRK09452  323 TLDSVVELENGKMvmvsefFNEDDPDFDHS---LGQKVAVTWVEGWEVVLADEE 373
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 34-364 1.86e-115

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 339.47  E-value: 1.86e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  34 LLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQR 113
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEIKPR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 114 CEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHD 193
Cdd:TIGR01187  81 VLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFVFVTHD 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 194 QEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSA-RLERAVEGRCRLDGILLRVPPQPELS--DG 270
Cdd:TIGR01187 161 QEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEAtVIERKSEQVVLAGVEGRRCDIYTDVPveKD 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 271 SAVLLVVRPELVTLCQLNEAsgaaadgggqrqGQENVLLGTVELRTFLGAVTRFRVRAAGGQLFTV------DLPglqAG 344
Cdd:TIGR01187 241 QPLHVVLRPEKIVIEEEDEA------------NSSNAIIGHVIDITYLGMTLEVHVRLETGQKVLVseffneDDP---HM 305

                         330       340
                  ....*....|....*....|
gi 1424145480 345 TLVPGQRVRLSFPPEACLVL 364
Cdd:TIGR01187 306 SPSIGDRVGLTWHPGSEVVL 325
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 4-216 2.37e-114

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 332.56  E-value: 2.37e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:cd03259     1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERRNIGMVFQD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:cd03259    81 YALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSA 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLG 216
Cdd:cd03259   161 LDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
3-286 9.05e-113

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 333.61  E-value: 9.05e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   3 FLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQ 82
Cdd:PRK11432    6 FVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRDICMVFQ 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:PRK11432   86 SYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLS 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSA 242
Cdd:PRK11432  166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDANIFPA 245

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1424145480 243 RLEravEGRCRLDGILLRVPP--QPELSDGSaVLLVVRPELVTLCQ 286
Cdd:PRK11432  246 TLS---GDYVDIYGYRLPRPAafAFNLPDGE-CTVGVRPEAITLSE 287
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
4-364 4.32e-106

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 317.55  E-value: 4.32e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:PRK11607   20 LEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPINMMFQS 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:PRK11607  100 YALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGA 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSAR 243
Cdd:PRK11607  180 LDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGV 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 244 LERAVEGRCRLD--GIL--LRVPPQPELSDGSAVLLVVRPELVTLCQlneasgaaadggGQRQGQENVLLGTVELRTFLG 319
Cdd:PRK11607  260 LKERQEDGLVIDspGLVhpLKVDADASVVDNVPVHVALRPEKIMLCE------------EPPADGCNFAVGEVIHIAYLG 327

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1424145480 320 AVTRFRVRAAGGQLFTVDLPG---LQAGTLVPGQRVRLSFPPEACLVL 364
Cdd:PRK11607  328 DLSIYHVRLKSGQMISAQLQNahrYRKGLPTWGDEVRLCWEADSCVVL 375
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 4-236 1.77e-104

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 308.50  E-value: 1.77e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:cd03296     3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERNVGFVFQH 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLR----RLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:cd03296    83 YALFRHMTVFDNVAFGLRVKprseRPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDE 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGA 236
Cdd:cd03296   163 PFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFLGE 239
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-249 4.19e-103

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 305.48  E-value: 4.19e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSF----GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITtRPANRRp 76
Cdd:COG1116     5 APALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVT-GPGPDR- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  77 mGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLL 156
Cdd:COG1116    83 -GVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 157 LDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGrleqLGTPEEIYR----RPRTVFV-- 230
Cdd:COG1116   162 MDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLSAR----PGRIVEEIDvdlpRPRDRELrt 237

                         250       260
                  ....*....|....*....|
gi 1424145480 231 -AGFVGASTRLSARLERAVE 249
Cdd:COG1116   238 sPEFAALRAEILDLLREEAE 257
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 4-216 5.24e-101

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 298.40  E-value: 5.24e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:cd03301     1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRDIAMVFQN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:cd03301    81 YALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSN 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLG 216
Cdd:cd03301   161 LDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 5-264 4.30e-99

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 297.00  E-value: 4.30e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVF 81
Cdd:COG1125     3 EFENVTKRYpDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLDPVelRRRIGYVI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 QSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGL--AERARSYPHQLSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:COG1125    83 QQIGLFPHMTVAENIATVPRLLGWDKERIRARVDELLELVGLdpEEYRDRYPHELSGGQQQRVGVARALAADPPILLMDE 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGAStR 239
Cdd:COG1125   163 PFGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPANDFVADFVGAD-R 241

                         250       260
                  ....*....|....*....|....*
gi 1424145480 240 LSARLERAvegrcRLDGILLRVPPQ 264
Cdd:COG1125   242 GLRRLSLL-----RVEDLMLPEPPT 261
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 4-240 8.13e-99

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 294.01  E-value: 8.13e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:TIGR00968   1 IEIANISKRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQDATRVHARDRKIGFVFQH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:TIGR00968  81 YALFKHLTVRDNIAFGLEIRKHPKAKIKARVEELLELVQLEGLGDRYPNQLSGGQRQRVALARALAVEPQVLLLDEPFGA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRL 240
Cdd:TIGR00968 161 LDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLGEVNVL 237
ABC_arch_GlcV NF040933
glucose ABC transporter ATP-binding protein GlcV;
6-348 1.91e-97

glucose ABC transporter ATP-binding protein GlcV;


Pssm-ID: 468866 [Multi-domain]  Cd Length: 357  Bit Score: 294.60  E-value: 1.91e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   6 LQELTKSFGK----TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-----PANRRP 76
Cdd:NF040933    5 VENVTKIFKKgkkeVVALDNVNLEIKSGEFFGILGPSGHGKTTFLRIIAGLEVPTDGEIYFDDKLVASPgkiivPPEDRN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  77 MGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLL 156
Cdd:NF040933   85 IGMVFQNWALYPNMTVFDNIAFPLKIKKVPKDEIEKKVKEVAEILGISEVLDRYPRELSGGQQQRVALARALVKNPQVLL 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 157 LDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGA 236
Cdd:NF040933  165 LDEPFSNLDARIRDSARALVKKIQRELKITTIIVSHDPADIFSLADRAGVINNGKFQQVGKPEEIYDNPANIFVARLIGD 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 237 STRLSARleraVEGRCRLDGILLRVPPQPELSDGSAVLLVVRPELVTLcqlneasgaaaDGGGQRQGQENVLLG--TVEL 314
Cdd:NF040933  245 INLLEGK----VEEEGLVDGNDLKIPLPNPKLEAGEVIIGIRPEDIDI-----------SESDMRLPPGFVEVGkgRVKV 309

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1424145480 315 RTFLGAVTRFRVRAAGG---QLFTVDLPGLQAGTLVP 348
Cdd:NF040933  310 SSYAGGVFRVVVSPIDDdsiEIIVNSDRPIEEGEEVN 346
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-360 1.70e-96

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 292.13  E-value: 1.70e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-PANRRpMG 78
Cdd:PRK11650    1 MAGLKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELePADRD-IA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEE---LLALVGLAERArsyPHQLSGGQQQRVALARALAVEPKVL 155
Cdd:PRK11650   80 MVFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEaarILELEPLLDRK---PRELSGGQRQRVAMGRAIVREPAVF 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 156 LLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVG 235
Cdd:PRK11650  157 LFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVASFIG 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 236 --ASTRLSARLERAVEGRCRLDGILLRVPPQPELSDGSAVLLVVRPELVTLCQlNEASGAAADGGGQRQGQENVLLGTVe 313
Cdd:PRK11650  237 spAMNLLDGRVSADGAAFELAGGIALPLGGGYRQYAGRKLTLGIRPEHIALSS-AEGGVPLTVDTVELLGADNLAHGRW- 314

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1424145480 314 lrtflgavtrfrvraaGGQLFTVDLPGlqAGTLVPGQRVRLSFPPEA 360
Cdd:PRK11650  315 ----------------GGQPLVVRLPH--QERPAAGSTLWLHLPANQ 343
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 4-209 5.25e-95

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 283.59  E-value: 5.25e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFG----KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITtRPANRRpmGM 79
Cdd:cd03293     1 LEVRNVSKTYGggggAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVT-GPGPDR--GY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:cd03293    78 VFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDE 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMAR 209
Cdd:cd03293   158 PFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSA 207
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 4-237 2.68e-90

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 272.25  E-value: 2.68e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTR-AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMV 80
Cdd:cd03295     1 IEFENVTKRYGGGKkAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVelRRKIGYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGL--AERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:cd03295    81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGAS 237
Cdd:cd03295   161 EPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFVGAD 239
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
4-242 1.50e-89

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 274.27  E-value: 1.50e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:PRK10851    3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQH 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRL--RRLPP--ALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:PRK10851   83 YALFRHMTVFDNIAFGLTVlpRRERPnaAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDE 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTR 239
Cdd:PRK10851  163 PFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMGEVNR 242


                  ...
gi 1424145480 240 LSA 242
Cdd:PRK10851  243 LQG 245
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
4-284 9.43e-89

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 272.33  E-value: 9.43e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFgKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:NF040840    2 IRIENLSKDW-KEFKLRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:NF040840   81 YMLFPHKTVFENIAFGLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSAR 243
Cdd:NF040840  161 LDVQTRDELIREMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFENIIEGV 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1424145480 244 LERAVEGR-CRLDGILLRVPPQPElsdgSAVLLVVRPELVTL 284
Cdd:NF040840  241 AEKGGEGTiLDTGNIKIELPEEKK----GKVRIGIRPEDITI 278
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 4-236 2.96e-88

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 266.89  E-value: 2.96e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRaVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:cd03299     1 LKVENLSKDWKEFK-LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRDISYVPQN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:cd03299    80 YALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSA 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGA 236
Cdd:cd03299   160 LDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLGF 232
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 4-227 2.22e-86

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 262.24  E-value: 2.22e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN----RRPMGM 79
Cdd:COG1126     2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKDinklRRKVGM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHMTAEQNVAFGLR-LRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:COG1126    82 VFQQFNLFPHLTVLENVTLAPIkVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLFD 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 159 EPLSALD-------AAVRVTLREEirriqqqlGMTVIYVTHDQEEALAISGRIAVMARGR-LEQlGTPEEIYRRPRT 227
Cdd:COG1126   162 EPTSALDpelvgevLDVMRDLAKE--------GMTMVVVTHEMGFAREVADRVVFMDGGRiVEE-GPPEEFFENPQH 229
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 7-234 3.71e-85

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 264.27  E-value: 3.71e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   7 QELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN------RRPMGMV 80
Cdd:COG4175    31 DEILEKTGQTVGVNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAGEVLIDGEDITKLSKKelrelrRKKMSMV 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:COG4175   111 FQHFALLPHRTVLENVAFGLEIQGVPKAERRERAREALELVGLAGWEDSYPDELSGGMQQRVGLARALATDPDILLMDEA 190

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFV 234
Cdd:COG4175   191 FSALDPLIRREMQDELLELQAKLKKTIVFITHDLDEALRLGDRIAIMKDGRIVQIGTPEEILTNPANDYVADFV 264
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 4-221 3.44e-84

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 256.44  E-value: 3.44e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-----RPANRRPMG 78
Cdd:COG1127     6 IEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGlsekeLYELRRRIG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPHMTAEQNVAFGLR-LRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:COG1127    86 MLFQGGALFDSLTVFENVAFPLReHTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEILLY 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 158 DEPLSALD---AAVRVTLreeIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:COG1127   166 DEPTAGLDpitSAVIDEL---IRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEEL 229
PhnT TIGR03258
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...
 6-359 1.31e-83

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.


Pssm-ID: 132302 [Multi-domain]  Cd Length: 362  Bit Score: 259.54  E-value: 1.31e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   6 LQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDA--GHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:TIGR03258   8 IDHLRVAYGANTVLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAAGltGRIAIADRDLTHAPPHKRGLALLFQN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:TIGR03258  88 YALFPHLKVEDNVAFGLRAQKMPKADIAERVADALKLVGLGDAAAHLPAQLSGGMQQRIAIARAIAIEPDVLLLDEPLSA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 164 LDAAVRVTLREEIRRIQQQL-GMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSA 242
Cdd:TIGR03258 168 LDANIRANMREEIAALHEELpELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAPADGFAAEFLGAANILPA 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 243 RLERAVEGRCRLD----GILLRVPPQPElSDGSAVLLVVRPELVTLcqlneasgaaadggGQRQGQENVLLGTVELRTFL 318
Cdd:TIGR03258 248 IALGITEAPGLVDvscgGAVIFAFGDGR-HDGRDKLACIRPEHLAL--------------TPRPAGEGRFHATIASVEWH 312

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 1424145480 319 GAVTRFRVRAAGGQLFTVDLPGLQAGTLVP--GQRVRLSFPPE 359
Cdd:TIGR03258 313 GAALHLLCDLDAACDEPMLVTMLRGRGPAPerGAKLALDCEAD 355
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
1-280 5.71e-82

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 255.34  E-value: 5.71e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMV 80
Cdd:PRK11000    1 MASVTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERGVGMV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCE---ELLALVGLAERArsyPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:PRK11000   81 FQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNqvaEVLQLAHLLDRK---PKALSGGQRQRVAIGRTLVAEPSVFLL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 158 DEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGAS 237
Cdd:PRK11000  158 DEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFIGSP 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1424145480 238 TR--LSARLERAVEGRCRL---DGILLRVPPQPE-LSDGSAVLLVVRPE 280
Cdd:PRK11000  238 KMnfLPVKVTATAIEQVQVelpNRQQVWLPVEGRgVQVGANMSLGIRPE 286
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 7-234 1.33e-81

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 251.02  E-value: 1.33e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   7 QELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT------RPANRRPMGMV 80
Cdd:cd03294    28 EEILKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAmsrkelRELRRKKISMV 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:cd03294   108 FQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEA 187

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFV 234
Cdd:cd03294   188 FSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFF 261
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 4-226 1.42e-79

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 253.67  E-value: 1.42e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-----GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN----- 73
Cdd:COG1123   261 LEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRslrel 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 RRPMGMVFQ--SYALFPHMTAEQNVAFGLRLRR-LPPALIRQRCEELLALVGLAERARS-YPHQLSGGQQQRVALARALA 149
Cdd:COG1123   341 RRRVQMVFQdpYSSLNPRMTVGDIIAEPLRLHGlLSRAERRERVAELLERVGLPPDLADrYPHELSGGQRQRVAIARALA 420

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 150 VEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:COG1123   421 LEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANPQ 497
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 4-221 8.16e-78

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 240.10  E-value: 8.16e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-----RPANRRPMG 78
Cdd:cd03261     1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGlseaeLYRLRRRMG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPHMTAEQNVAFGLR-LRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:cd03261    81 MLFQSGALFDSLTVFENVAFPLReHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLY 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 158 DEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:cd03261   161 DEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 11-235 2.15e-76

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 240.91  E-value: 2.15e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  11 KSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT------RPANRRPMGMVFQSY 84
Cdd:TIGR01186   1 KKTGGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKqspvelREVRRKKIGMVFQQF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  85 ALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSAL 164
Cdd:TIGR01186  81 ALFPHMTILQNTSLGPELLGWPEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSAL 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 165 DAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVG 235
Cdd:TIGR01186 161 DPLIRDSMQDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIG 231
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
4-224 2.91e-76

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 236.11  E-value: 2.91e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-RRPMGMVFQ 82
Cdd:COG1131     1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEvRRRIGYVPQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:COG1131    81 EPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTS 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:COG1131   161 GLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKAR 221
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 4-211 8.72e-76

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 232.85  E-value: 8.72e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT----RPANRRPMGM 79
Cdd:cd03229     1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDledeLPPLRRRIGM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHMTAEQNVAFGLrlrrlppalirqrceellalvglaerarsyphqlSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:cd03229    81 VFQDFALFPHLTVLENIALGL----------------------------------SGGQQQRVALARALAMDPDVLLLDE 126

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:cd03229   127 PTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
4-213 1.18e-75

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 234.17  E-value: 1.18e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFG----KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN------ 73
Cdd:COG1136     5 LELRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERelarlr 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 RRPMGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:COG1136    85 RRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPK 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDqEEALAISGRIAVMARGRLE 213
Cdd:COG1136   165 LILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHD-PELAARADRVIRLRDGRIV 223
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 4-212 8.33e-75

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 232.00  E-value: 8.33e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFG----KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN------ 73
Cdd:cd03255     1 IELKNLSKTYGgggeKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKelaafr 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 RRPMGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:cd03255    81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEAlAISGRIAVMARGRL 212
Cdd:cd03255   161 IILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELA-EYADRIIELRDGKI 218
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 4-212 1.16e-74

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 231.26  E-value: 1.16e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN----RRPMGM 79
Cdd:cd03262     1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNinelRQKVGM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHMTAEQNVAFGLR-LRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:cd03262    81 VFQQFNLFPHLTVLENITLAPIkVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 159 EPLSALDAAvrvtLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:cd03262   161 EPTSALDPE----LVGEVLDVMKDLaeeGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
4-261 6.38e-74

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 233.82  E-value: 6.38e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF----GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT------RPAn 73
Cdd:COG1135     2 IELENLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTAlserelRAA- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 RRPMGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:COG1135    81 RRKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 154 VLLLDEPLSALD----AAVrVTLreeIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVF 229
Cdd:COG1135   161 VLLCDEATSALDpettRSI-LDL---LKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFANPQSEL 236

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1424145480 230 VAGFVGASTRLSARLERAVEGRCRL-DGILLRV 261
Cdd:COG1135   237 TRRFLPTVLNDELPEELLARLREAAgGGRLVRL 269
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 4-243 8.26e-73

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 227.76  E-value: 8.26e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGK----TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP--ANRRPM 77
Cdd:COG1124     2 LEVRNLSVSYGQggrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRrkAFRRRV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSY--ALFPHMTAEQNVAFGLRLRRLPPalIRQRCEELLALVGLAERARS-YPHQLSGGQQQRVALARALAVEPKV 154
Cdd:COG1124    82 QMVFQDPyaSLHPRHTVDRILAEPLRIHGLPD--REERIAELLEQVGLPPSFLDrYPHQLSGGQRQRVAIARALILEPEL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 155 LLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFV 234
Cdd:COG1124   160 LLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPKHPYTRELL 239


                  ....*....
gi 1424145480 235 GASTRLSAR 243
Cdd:COG1124   240 AASLAFERA 248
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-208 1.80e-72

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 227.44  E-value: 1.80e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTR----AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRrp 76
Cdd:COG4525     1 MSMLTVRHVSVRYPGGGqpqpALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGADR-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  77 mGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLL 156
Cdd:COG4525    79 -GVVFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLL 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 157 LDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMA 208
Cdd:COG4525   158 MDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVMS 209
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 4-226 1.38e-71

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 224.00  E-value: 1.38e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFG----KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT------RPAn 73
Cdd:cd03258     2 IELKNVSKVFGdtggKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLlsgkelRKA- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 RRPMGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:cd03258    81 RRRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPK 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:cd03258   161 VLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANPQ 233
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 4-227 4.54e-71

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 222.59  E-value: 4.54e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMV 80
Cdd:COG1122     1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRelRRKVGLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQS--YALFpHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:COG1122    81 FQNpdDQLF-APTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLD 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRT 227
Cdd:COG1122   160 EPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDYEL 227
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 29-216 2.90e-70

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 220.24  E-value: 2.90e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  29 GEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHI------LLDQEEITTRPANRRPMGMVFQSYALFPHMTAEQNVAFGLRl 102
Cdd:cd03297    23 EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIvlngtvLFDSRKKINLPPQQRKIGLVFQQYALFPHLNVRENLAFGLK- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 103 rRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQ 182
Cdd:cd03297   102 -RKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQIKKN 180

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1424145480 183 LGMTVIYVTHDQEEALAISGRIAVMARGRLEQLG 216
Cdd:cd03297   181 LNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 34-285 7.01e-69

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 221.51  E-value: 7.01e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  34 LLGPSGCGKTTVLRLVAGFEQPDAGHI------LLDQEEITTRPANRRPMGMVFQSYALFPHMTAEQNVAFGLRlrRLPP 107
Cdd:COG4148    30 LFGPSGSGKTTLLRAIAGLERPDSGRIrlggevLQDSARGIFLPPHRRRIGYVFQEARLFPHLSVRGNLLYGRK--RAPR 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 108 ALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTV 187
Cdd:COG4148   108 AERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILPYLERLRDELDIPI 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 188 IYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSARLERAVEG----RCRLDGILLRVpP 263
Cdd:COG4148   188 LYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLLPLAGGEEAGSVLEATVAAHDPDygltRLALGGGRLWV-P 266

                         250       260
                  ....*....|....*....|..
gi 1424145480 264 QPELSDGSAVLLVVRPELVTLC 285
Cdd:COG4148   267 RLDLPPGTRVRVRIRARDVSLA 288
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
4-236 9.95e-69

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 216.54  E-value: 9.95e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAveRISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:COG3840     2 LRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERPVSMLFQE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:COG3840    80 NNLFPHLTVAQNIGLGLRPGLKLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSA 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVGA 236
Cdd:COG3840   160 LDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLGI 232
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 4-216 1.34e-68

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 216.22  E-value: 1.34e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF----GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-----RPANR 74
Cdd:cd03257     2 LEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKlsrrlRKIRR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 RPMGMVFQSY--ALFPHMTAEQNVAFGLRLRRLP--PALIRQRCEELLALVGLAE-RARSYPHQLSGGQQQRVALARALA 149
Cdd:cd03257    82 KEIQMVFQDPmsSLNPRMTIGEQIAEPLRIHGKLskKEARKEAVLLLLVGVGLPEeVLNRYPHELSGGQRQRVAIARALA 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 150 VEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLG 216
Cdd:cd03257   162 LNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
4-225 6.20e-68

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 214.96  E-value: 6.20e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN----RRPMGM 79
Cdd:PRK09493    2 IEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDerliRQEAGM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHMTAEQNVAFG-LRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:PRK09493   82 VFQQFYLFPHLTALENVMFGpLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFD 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 159 EPLSALDAavrvTLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PRK09493  162 EPTSALDP----ELRHEVLKVMQDLaeeGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNP 227
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 1-226 6.62e-66

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 210.28  E-value: 6.62e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP-MGM 79
Cdd:COG0411     2 DPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIArLGI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 V--FQSYALFPHMTAEQNVAFGLRLR----------RLPPAL-----IRQRCEELLALVGLAERARSYPHQLSGGQQQRV 142
Cdd:COG0411    82 ArtFQNPRLFPELTVLENVLVAAHARlgrgllaallRLPRARreereARERAEELLERVGLADRADEPAGNLSYGQQRRL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 143 ALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIY 222
Cdd:COG0411   162 EIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEVR 241


                  ....
gi 1424145480 223 RRPR 226
Cdd:COG0411   242 ADPR 245
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
4-212 1.32e-64

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 205.67  E-value: 1.32e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTR-AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-----RPANRRPM 77
Cdd:COG2884     2 IRFENVSKRYPGGReALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRlkrreIPYLRRRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:COG2884    82 GVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLA 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 158 DEPLSALDAAvrvtLREEI----RRIqQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:COG2884   162 DEPTGNLDPE----TSWEImellEEI-NRRGTTVLIATHDLELVDRMPKRVLELEDGRL 215
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 4-226 1.86e-63

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 206.06  E-value: 1.86e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF----GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQP---DAGHILLDQEEITTRPANR-- 74
Cdd:COG0444     2 LEVRNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKLSEKElr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 ----RPMGMVFQ-SY-ALFPHMTAEQNVAFGLRL-RRLPPALIRQRCEELLALVGL---AERARSYPHQLSGGQQQRVAL 144
Cdd:COG0444    82 kirgREIQMIFQdPMtSLNPVMTVGDQIAEPLRIhGGLSKAEARERAIELLERVGLpdpERRLDRYPHELSGGMRQRVMI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 145 ARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:COG0444   162 ARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFEN 241


                  ..
gi 1424145480 225 PR 226
Cdd:COG0444   242 PR 243
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 4-221 5.73e-63

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 201.64  E-value: 5.73e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFE-----QPDAGHILLDQEEITTRPAN----R 74
Cdd:cd03260     1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNdlipgAPDEGEVLLDGKDIYDLDVDvlelR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 RPMGMVFQSYALFPhMTAEQNVAFGLRLRR-LPPALIRQRCEELLALVGLAERA--RSYPHQLSGGQQQRVALARALAVE 151
Cdd:cd03260    81 RRVGMVFQKPNPFP-GSIYDNVAYGLRLHGiKLKEELDERVEEALRKAALWDEVkdRLHALGLSGGQQQRLCLARALANE 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 152 PKVLLLDEPLSALDAAVRVTLREEIRRIQQQlgMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:cd03260   160 PEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 4-226 9.72e-63

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 209.76  E-value: 9.72e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF--GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDA---GHILLDQEEITTRPANRRP-- 76
Cdd:COG1123     5 LEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGrisGEVLLDGRDLLELSEALRGrr 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  77 MGMVFQS--YALFPhMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKV 154
Cdd:COG1123    85 IGMVFQDpmTQLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDL 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 155 LLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:COG1123   164 LIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQ 235
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 4-246 2.88e-62

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 201.12  E-value: 2.88e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF--GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEiTTRPAN----RRPM 77
Cdd:TIGR04520   1 IEVENVSFSYpeSEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLD-TLDEENlweiRKKV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSyalfPH-----MTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEP 152
Cdd:TIGR04520  80 GMVFQN----PDnqfvgATVEDDVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRP 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 153 KVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEAlAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAG 232
Cdd:TIGR04520 156 DIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEA-VLADRVIVMNKGKIVAEGTPREIFSQVELLKEIG 234

                         250
                  ....*....|....*
gi 1424145480 233 F-VGASTRLSARLER 246
Cdd:TIGR04520 235 LdVPFITELAKALKK 249
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 4-226 3.66e-62

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 199.97  E-value: 3.66e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP---MGMV 80
Cdd:cd03219     1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIArlgIGRT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPAL----------IRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAV 150
Cdd:cd03219    81 FQIPRLFPELTVLENVMVAAQARTGSGLLlararreereARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALAT 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 151 EPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:cd03219   161 DPKLLLLDEPAAGLNPEETEELAELIRELRER-GITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNPR 235
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 5-211 1.48e-61

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 197.69  E-value: 1.48e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSF--GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMV 80
Cdd:cd03225     1 ELKNLSFSYpdGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKelRRKVGLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQsyalFP-HM----TAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVL 155
Cdd:cd03225    81 FQ----NPdDQffgpTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDIL 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 156 LLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:cd03225   157 LLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 5-261 1.88e-61

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 201.57  E-value: 1.88e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSF-GKTRAVE---RISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-----RR 75
Cdd:PRK11153    3 ELKNISKVFpQGGRTIHalnNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKelrkaRR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  76 PMGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVL 155
Cdd:PRK11153   83 QIGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 156 LLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFVG 235
Cdd:PRK11153  163 LCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHPLTREFIQ 242

                         250       260
                  ....*....|....*....|....*....
gi 1424145480 236 ASTRLS---ARLERAVEGRCRLDGILLRV 261
Cdd:PRK11153  243 STLHLDlpeDYLARLQAEPTTGSGPLLRL 271
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 4-226 2.21e-61

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 201.11  E-value: 2.21e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-----------GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPA 72
Cdd:COG4608     8 LEVRDLKKHFpvrgglfgrtvGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  73 N-----RRPMGMVFQ-SYA-LFPHMTAEQNVAFGLRLRRL-PPALIRQRCEELLALVGL-AERARSYPHQLSGGQQQRVA 143
Cdd:COG4608    88 RelrplRRRMQMVFQdPYAsLNPRMTVGDIIAEPLRIHGLaSKAERRERVAELLELVGLrPEHADRYPHEFSGGQRQRIG 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 144 LARALAVEPKVLLLDEPLSALDAAVR---VTLreeIRRIQQQLGMTVIYVTHDqeeaLA----ISGRIAVMARGRLEQLG 216
Cdd:COG4608   168 IARALALNPKLIVCDEPVSALDVSIQaqvLNL---LEDLQDELGLTYLFISHD----LSvvrhISDRVAVMYLGKIVEIA 240

                         250
                  ....*....|
gi 1424145480 217 TPEEIYRRPR 226
Cdd:COG4608   241 PRDELYARPL 250
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 4-224 6.57e-61

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 197.00  E-value: 6.57e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP-ANRRPMGMVFQ 82
Cdd:COG4555     2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPrEARRQIGVLPD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:COG4555    82 ERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTN 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:COG4555   162 GLDVMARRLLREILRALKKE-GKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREE 222
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 19-226 7.52e-60

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 193.84  E-value: 7.52e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  19 VERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITtRPANRRPMgmVFQSYALFPHMTAEQNVAF 98
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQIT-EPGPDRMV--VFQNYSLLPWLTVRENIAL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  99 GLR--LRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEI 176
Cdd:TIGR01184  78 AVDrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEEL 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 177 RRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI-YRRPR 226
Cdd:TIGR01184 158 MQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEVpFPRPR 208
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 4-221 2.14e-59

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 193.34  E-value: 2.14e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANR--RPMGMVF 81
Cdd:COG1120     2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRElaRRIAYVP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 QSYALFPHMTAEQNVAFGL-----RLRRLPPALiRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLL 156
Cdd:COG1120    82 QEPPAPFGLTVRELVALGRyphlgLFGRPSAED-REAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 157 LDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:COG1120   161 LDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEV 225
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 4-221 2.15e-59

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 193.35  E-value: 2.15e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-----RRPM 77
Cdd:COG3638     3 LELRNLSKRYpGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRalrrlRRRI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGL--------RLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALA 149
Cdd:COG3638    83 GMIFQQFNLVPRLSVLTNVLAGRlgrtstwrSLLGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVAIARALV 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 150 VEPKVLLLDEPLSALD--AAVRVTlrEEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:COG3638   163 QEPKLILADEPVASLDpkTARQVM--DLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAEL 234
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
4-227 2.36e-59

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 193.48  E-value: 2.36e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR--------PANRR 75
Cdd:COG4598     9 LEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKpdrdgelvPADRR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  76 P-------MGMVFQSYALFPHMTAEQNVAFG-LRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARA 147
Cdd:COG4598    89 QlqrirtrLGMVFQSFNLWSHMTVLENVIEApVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAIARA 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 148 LAVEPKVLLLDEPLSALDAavrvTLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:COG4598   169 LAMEPEVMLFDEPTSALDP----ELVGEVLKVMRDLaeeGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGN 244


                  ...
gi 1424145480 225 PRT 227
Cdd:COG4598   245 PKS 247
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 4-199 2.60e-57

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 186.53  E-value: 2.60e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDA---GHILLDQEEITTRPANRRPMGMV 80
Cdd:COG4136     2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAFsasGEVLLNGRRLTALPAEQRRIGIL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRlRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:COG4136    82 FQDDLLFPHLSVGENLAFALP-PTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEP 160

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALA 199
Cdd:COG4136   161 FSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPA 199
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 4-225 3.94e-57

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 188.43  E-value: 3.94e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGK-----TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN----- 73
Cdd:TIGR04521   1 IKLKNVSYIYQPgtpfeKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKklkdl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 RRPMGMVFQ--SYALFpHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAE--RARSyPHQLSGGQQQRVALARALA 149
Cdd:TIGR04521  81 RKKVGLVFQfpEHQLF-EETVYKDIAFGPKNLGLSEEEAEERVKEALELVGLDEeyLERS-PFELSGGQMRRVAIAGVLA 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 150 VEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:TIGR04521 159 MEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDV 234
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 4-212 3.94e-57

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 184.91  E-value: 3.94e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-RRPMGMVFQ 82
Cdd:cd03230     1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEvKRRIGYLPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVafglrlrrlppalirqrceellalvglaerarsyphQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:cd03230    81 EPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPELLILDEPTS 124

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:cd03230   125 GLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 4-214 4.61e-57

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 186.49  E-value: 4.61e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAV----ERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-----RPANR 74
Cdd:COG4181     9 IELRGLTKTVGTGAGEltilKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFAldedaRARLR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 -RPMGMVFQSYALFPHMTAEQNVAFGLRLRRLPPAliRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:COG4181    89 aRHVGFVFQSFQLLPTLTALENVMLPLELAGRRDA--RARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPA 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEAlAISGRIAVMARGRLEQ 214
Cdd:COG4181   167 ILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALA-ARCDRVLRLRAGRLVE 226
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 4-211 5.50e-57

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 185.91  E-value: 5.50e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-----PANRRPM 77
Cdd:TIGR02673   2 IEFHNVSKAYpGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLrgrqlPLLRRRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:TIGR02673  82 GVVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLA 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 158 DEPLSALDAAvrvtLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:TIGR02673 162 DEPTGNLDPD----LSERILDLLKRLnkrGTTVIVATHDLSLVDRVAHRVIILDDGR 214
3a0107s01c2 TIGR00972
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ...
 4-226 1.07e-56

phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]


Pssm-ID: 273372 [Multi-domain]  Cd Length: 247  Bit Score: 186.35  E-value: 1.07e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLR-------LVAGFEQpdAGHILLDQEEITTRPAN--- 73
Cdd:TIGR00972   2 IEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRslnrmndLVPGVRI--EGKVLFDGQDIYDKKIDvve 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 -RRPMGMVFQSYALFPhMTAEQNVAFGLRLR-RLPPALIRQRCEELLALVGLAE----RARSYPHQLSGGQQQRVALARA 147
Cdd:TIGR00972  80 lRRRVGMVFQKPNPFP-MSIYDNIAYGPRLHgIKDKKELDEIVEESLKKAALWDevkdRLHDSALGLSGGQQQRLCIARA 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 148 LAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlgMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:TIGR00972 159 LAVEPEVLLLDEPTSALDPIATGKIEELIQELKKK--YTIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTNPK 235
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 4-221 1.11e-55

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 183.54  E-value: 1.11e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFG-KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP-----ANRRPM 77
Cdd:cd03256     1 IEVENLSKTYPnGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKgkalrQLRRQI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFG-------LR-LRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALA 149
Cdd:cd03256    81 GMIFQQFNLIERLSVLENVLSGrlgrrstWRsLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALM 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 150 VEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:cd03256   161 QQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
4-212 1.19e-55

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 182.32  E-value: 1.19e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVF 81
Cdd:COG4619     1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPewRRQVAYVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 QSYALFPhMTAEQNVAFGLRLRRLPPAliRQRCEELLALVGLAERARSYP-HQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:COG4619    81 QEPALWG-GTVRDNLPFPFQLRERKFD--RERALELLERLGLPPDILDKPvERLSGGERQRLALIRALLLQPDVLLLDEP 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:COG4619   158 TSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 4-221 1.55e-54

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 179.62  E-value: 1.55e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTR--AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-RPANRRPMGMV 80
Cdd:cd03263     1 LQIRNLTKTYKKGTkpAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTdRKAARQSLGYC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:cd03263    81 PQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEP 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQqlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:cd03263   161 TSGLDPASRRAIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQEL 219
ectoine_ehuA TIGR03005
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ...
 4-236 1.72e-54

ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of a conserved four gene ABC transporter operon found next to ectoine unilization operons and ectoine biosynthesis operons. Ectoine is a compatible solute that protects enzymes from high osmolarity. It is released by some species in response to hypoosmotic shock, and it is taken up by a number of bacteria as a compatible solute or for consumption. This family shows strong sequence similiarity to a number of amino acid ABC transporter ATP-binding proteins.


Pssm-ID: 132050 [Multi-domain]  Cd Length: 252  Bit Score: 180.80  E-value: 1.72e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN---------- 73
Cdd:TIGR03005   1 VRFSDVTKRFGILTVLDGLNFSVAAGEKVALIGPSGSGKSTILRILMTLEPIDEGQIQVEGEQLYHMPGRngplvpadek 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 -----RRPMGMVFQSYALFPHMTAEQNVAFG-LRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARA 147
Cdd:TIGR03005  81 hlrqmRNKIGMVFQSFNLFPHKTVLDNVTEApVLVLGMARAEAEKRAMELLDMVGLADKADHMPAQLSGGQQQRVAIARA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 148 LAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRT 227
Cdd:TIGR03005 161 LAMRPKVMLFDEVTSALDPELVGEVLNVIRRLASEHDLTMLLVTHEMGFAREFADRVCFFDKGRIVEQGKPDEIFRQPKE 240


                  ....*....
gi 1424145480 228 VFVAGFVGA 236
Cdd:TIGR03005 241 ERTREFLSK 249
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-221 5.97e-54

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 179.13  E-value: 5.97e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRpanRRPMGMV 80
Cdd:COG1121     4 MPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRA---RRRIGYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYAL---FPhMTAEQNVAFGL----RLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:COG1121    81 PQRAEVdwdFP-ITVRDVVLMGRygrrGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPD 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQlGTPEEI 221
Cdd:COG1121   160 LLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLLNRGLVAH-GPPEEV 225
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 4-212 8.48e-54

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 177.69  E-value: 8.48e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAveRISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:cd03298     1 VRLDKIRFSYGEQPM--HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSMLFQE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:cd03298    79 NNLFAHLTVEQNVGLGLSPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAA 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:cd03298   159 LDPALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 4-221 9.50e-54

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 177.56  E-value: 9.50e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-RRPMGMVFQ 82
Cdd:cd03265     1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREvRRRIGIVFQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:cd03265    81 DLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTI 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:cd03265   161 GLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 1-226 1.43e-53

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 177.91  E-value: 1.43e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP-MGM 79
Cdd:COG1137     1 MMTLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRArLGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 vfqSY-----ALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKV 154
Cdd:COG1137    81 ---GYlpqeaSIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKF 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 155 LLLDEPLSALDA-AVrvtlrEEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:COG1137   158 ILLDEPFAGVDPiAV-----ADIQKIIRHLkerGIGVLITDHNVRETLGICDRAYIISEGKVLAEGTPEEILNNPL 228
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 4-226 5.49e-52

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 174.45  E-value: 5.49e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLR-------LVAGFEQpdAGHILLDQEEITTRPAN--- 73
Cdd:COG1117    12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRclnrmndLIPGARV--EGEILLDGEDIYDPDVDvve 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 -RRPMGMVFQSYALFPhMTAEQNVAFGLRLR-RLPPALIRQRCEELLALVGL----AERARSYPHQLSGGQQQRVALARA 147
Cdd:COG1117    90 lRRRVGMVFQKPNPFP-KSIYDNVAYGLRLHgIKSKSELDEIVEESLRKAALwdevKDRLKKSALGLSGGQQQRLCIARA 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 148 LAVEPKVLLLDEPLSALD--AAVRVtlrEE-IRRIQQQlgMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:COG1117   169 LAVEPEVLLMDEPTSALDpiSTAKI---EElILELKKD--YTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIFTN 243


                  ..
gi 1424145480 225 PR 226
Cdd:COG1117   244 PK 245
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 4-222 7.80e-52

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 173.64  E-value: 7.80e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGK-TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-----RRPM 77
Cdd:TIGR02315   2 LEVENLSKVYPNgKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKklrklRRRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGlRL----------RRLPPAlIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARA 147
Cdd:TIGR02315  82 GMIFQHYNLIERLTVLENVLHG-RLgykptwrsllGRFSEE-DKERALSALERVGLADKAYQRADQLSGGQQQRVAIARA 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 148 LAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIY 222
Cdd:TIGR02315 160 LAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELD 234
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 4-212 2.41e-51

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 171.44  E-value: 2.41e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-----RRPM 77
Cdd:cd03292     1 IEFINVTKTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRaipylRRKI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:cd03292    81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 158 DEPLSALDAAvrvTLREEIRRIQQ--QLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:cd03292   161 DEPTGNLDPD---TTWEIMNLLKKinKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
4-233 4.21e-51

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 176.38  E-value: 4.21e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT------RPANRRPM 77
Cdd:PRK10070   29 LSKEQILEKTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKisdaelREVRRKKI 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:PRK10070  109 AMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLM 188

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 158 DEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGF 233
Cdd:PRK10070  189 DEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTF 264
cbiO PRK13650
energy-coupling factor transporter ATPase;
19-224 4.74e-51

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 172.61  E-value: 4.74e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  19 VERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITtrPAN----RRPMGMVFQSY-ALFPHMTAE 93
Cdd:PRK13650   23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLT--EENvwdiRHKIGMVFQNPdNQFVGATVE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  94 QNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLR 173
Cdd:PRK13650  101 DDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELI 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 174 EEIRRIQQQLGMTVIYVTHDQEEaLAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:PRK13650  181 KTIKGIRDDYQMTVISITHDLDE-VALSDRVLVMKNGQVESTSTPRELFSR 230
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
4-210 5.69e-51

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 171.81  E-value: 5.69e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRrpmGMVFQS 83
Cdd:PRK11248    2 LQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER---GVVFQN 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:PRK11248   79 EGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGA 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARG 210
Cdd:PRK11248  159 LDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPG 205
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 21-216 9.52e-51

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 169.66  E-value: 9.52e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  21 RISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQSYALFPHMTAEQNVAFGL 100
Cdd:TIGR01277  16 EFDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQRPVSMLFQENNLFAHLTVRQNIGLGL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 101 RLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQ 180
Cdd:TIGR01277  96 HPGLKLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQLC 175

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1424145480 181 QQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLG 216
Cdd:TIGR01277 176 SERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
4-233 1.00e-50

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 170.58  E-value: 1.00e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAG--HILLDQEEITTRPAN------RR 75
Cdd:COG4161     3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGqlNIAGHQFDFSQKPSEkairllRQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  76 PMGMVFQSYALFPHMTAEQN-VAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKV 154
Cdd:COG4161    83 KVGMVFQQYNLWPHLTVMENlIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQV 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 155 LLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTpEEIYRRPRTVFVAGF 233
Cdd:COG4161   163 LLFDEPTAALDPEITAQVVEIIRELSQT-GITQVIVTHEVEFARKVASQVVYMEKGRIIEQGD-ASHFTQPQTEAFAHY 239
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-226 1.04e-50

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 178.34  E-value: 1.04e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGK----TRAVERISLGVERGEFLTLLGPSGCGKT----TVLRLVAGFEQPDAGHILLDQEEITTRPA 72
Cdd:COG4172     4 MPLLSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLGLSE 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  73 NR------RPMGMVFQ--SYALFPHMTAEQNVAFGLRL-RRLPPALIRQRCEELLALVGLAE---RARSYPHQLSGGQQQ 140
Cdd:COG4172    84 RElrrirgNRIAMIFQepMTSLNPLHTIGKQIAEVLRLhRGLSGAAARARALELLERVGIPDperRLDAYPHQLSGGQRQ 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 141 RVALARALAVEPKVLLLDEPLSALDaavrVTLREEI----RRIQQQLGMTVIYVTHDqeeaLAISGRIA----VMARGRL 212
Cdd:COG4172   164 RVMIAMALANEPDLLIADEPTTALD----VTVQAQIldllKDLQRELGMALLLITHD----LGVVRRFAdrvaVMRQGEI 235

                         250
                  ....*....|....
gi 1424145480 213 EQLGTPEEIYRRPR 226
Cdd:COG4172   236 VEQGPTAELFAAPQ 249
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
9-212 3.26e-50

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 168.36  E-value: 3.26e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   9 LTKSFgKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-----RPANRRPM-GMVFQ 82
Cdd:NF038007   12 ITKTI-KTKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNlsysqKIILRRELiGYIFQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:NF038007   91 SFNLIPHLSIFDNVALPLKYRGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLADEPTG 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQlGMTVIYVTHdQEEALAISGRIAVMARGRL 212
Cdd:NF038007  171 NLDSKNARAVLQQLKYINQK-GTTIIMVTH-SDEASTYGNRIINMKDGKL 218
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 4-199 4.62e-50

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 167.66  E-value: 4.62e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-RRPMGMVFQ 82
Cdd:COG4133     3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDyRRRLAYLGH 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPAliRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:COG4133    83 ADGLKPELTVRENLRFWAALYGLRAD--REAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFT 160

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1424145480 163 ALDAAVRVTLREEIRRiQQQLGMTVIYVTHDQEEALA 199
Cdd:COG4133   161 ALDAAGVALLAELIAA-HLARGGAVLLTTHQPLELAA 196
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 4-227 2.64e-49

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 174.49  E-value: 2.64e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-----------GKTRAVERISLGVERGEFLTLLGPSGCGKTT----VLRLVagfeqPDAGHILLDQEEIT 68
Cdd:COG4172   276 LEARDLKVWFpikrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTlglaLLRLI-----PSEGEIRFDGQDLD 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  69 TRPAN-----RRPMGMVFQS-YA-LFPHMTAEQNVAFGLRLRR--LPPALIRQRCEELLALVGLAERARS-YPHQLSGGQ 138
Cdd:COG4172   351 GLSRRalrplRRRMQVVFQDpFGsLSPRMTVGQIIAEGLRVHGpgLSAAERRARVAEALEEVGLDPAARHrYPHEFSGGQ 430

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 139 QQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTP 218
Cdd:COG4172   431 RQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPT 510


                  ....*....
gi 1424145480 219 EEIYRRPRT 227
Cdd:COG4172   511 EQVFDAPQH 519
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 4-217 1.06e-48

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 165.19  E-value: 1.06e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAG--HILLDQEEITTRPAN------RR 75
Cdd:PRK11124    3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGtlNIAGNHFDFSKTPSDkairelRR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  76 PMGMVFQSYALFPHMTAEQN-VAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKV 154
Cdd:PRK11124   83 NVGMVFQQYNLWPHLTVQQNlIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQV 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 155 LLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGT 217
Cdd:PRK11124  163 LLFDEPTAALDPEITAQIVSIIRELAET-GITQVIVTHEVEVARKTASRVVYMENGHIVEQGD 224
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-162 1.07e-48

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 162.05  E-value: 1.07e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  19 VERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMVFQSYALFPHMTAEQNV 96
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTddERKSLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  97 AFGLRLRRLPPALIRQRCEELLALVGL----AERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLgdlaDRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
21-221 1.14e-48

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 164.76  E-value: 1.14e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  21 RISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQSYALFPHMTAEQNVAFGL 100
Cdd:PRK10771   17 RFDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 101 RlrrlpPALI-----RQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVR---VTL 172
Cdd:PRK10771   97 N-----PGLKlnaaqREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRqemLTL 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1424145480 173 REEIRRIQQqlgMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK10771  172 VSQVCQERQ---LTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 4-212 1.37e-48

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 165.62  E-value: 1.37e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIL-----LDQEEITTRpanrrpmg 78
Cdd:PRK11247   13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLagtapLAEAREDTR-------- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPHMTAEQNVAFGLRlrrlppALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:PRK11247   85 LMFQDARLLPWKKVIDNVGLGLK------GQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLD 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:PRK11247  159 EPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 4-225 3.76e-48

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 163.48  E-value: 3.76e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP-MGMVF- 81
Cdd:cd03218     1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRArLGIGYl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 -QSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:cd03218    81 pQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEP 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 161 LSALDA-AVRvtlreEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:cd03218   161 FAGVDPiAVQ-----DIQKIIKILkdrGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANE 224
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 1-226 6.75e-48

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 163.38  E-value: 6.75e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEI-TTRPAN------ 73
Cdd:PRK11264    1 MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIdTARSLSqqkgli 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 ---RRPMGMVFQSYALFPHMTAEQNVAFG-LRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALA 149
Cdd:PRK11264   81 rqlRQHVGFVFQNFNLFPHRTVLENIIEGpVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 150 VEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIyVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:PRK11264  161 MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVI-VTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQ 236
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
15-224 1.59e-47

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 163.26  E-value: 1.59e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  15 KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAG-----HILLDQE---EIttrpanRRPMGMVFQSY-A 85
Cdd:PRK13635   19 ATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGtitvgGMVLSEEtvwDV------RRQVGMVFQNPdN 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  86 LFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALD 165
Cdd:PRK13635   93 QFVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLD 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 166 AAVRVTLREEIRRIQQQLGMTVIYVTHDQEEAlAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:PRK13635  173 PRGRREVLETVRQLKEQKGITVLSITHDLDEA-AQADRVIVMNKGEILEEGTPEEIFKS 230
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 4-216 1.62e-47

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 161.21  E-value: 1.62e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGeFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-RRPMGMVFQ 82
Cdd:cd03264     1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKlRRRIGYLPQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:cd03264    80 EFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 163 ALDAAVRVTLREEIRRIQQqlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLG 216
Cdd:cd03264   160 GLDPEERIRFRNLLSELGE--DRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1-212 1.65e-47

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 169.04  E-value: 1.65e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEI---TTRPANRRPM 77
Cdd:COG1129     2 EPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVrfrSPRDAQAAGI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGLRLRRLP---PALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKV 154
Cdd:COG1129    82 AIIHQELNLVPNLSVAENIFLGREPRRGGlidWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDARV 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 155 LLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:COG1129   162 LILDEPTASLTEREVERLFRIIRRLKAQ-GVAIIYISHRLDEVFEIADRVTVLRDGRL 218
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 4-212 9.09e-47

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 159.46  E-value: 9.09e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTR----AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-RRPMG 78
Cdd:cd03266     2 ITADALTKRFRDVKktvqAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEaRRRLG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:cd03266    82 FVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLD 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 159 EPLSALDAAVRVTLREEIRRiQQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:cd03266   162 EPTTGLDVMATRALREFIRQ-LRALGKCILFSTHIMQEVERLCDRVVVLHRGRV 214
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 5-211 9.23e-47

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 157.41  E-value: 9.23e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDqeeittrpanrrpmgmvfqsy 84
Cdd:cd00267     1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILID--------------------- 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  85 alfphmtaeqnvafGLRLRRLPPALIRQRCeellalvglaerarSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSAL 164
Cdd:cd00267    60 --------------GKDIAKLPLEELRRRI--------------GYVPQLSGGQRQRVALARALLLNPDLLLLDEPTSGL 111

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1424145480 165 DAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:cd00267   112 DPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 5-212 1.33e-46

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 157.60  E-value: 1.33e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAnrrpmgmvfqsy 84
Cdd:cd03214     1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSP------------ 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  85 alfphmtAEqnvafglRLRRLppALIRQrceeLLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSAL 164
Cdd:cd03214    69 -------KE-------LARKI--AYVPQ----ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHL 128

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1424145480 165 DAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:cd03214   129 DIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRI 176
cbiO PRK13637
energy-coupling factor transporter ATPase;
16-223 1.59e-46

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 160.98  E-value: 1.59e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  16 TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN----RRPMGMVFQ--SYALFPH 89
Cdd:PRK13637   20 KKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKlsdiRKKVGLVFQypEYQLFEE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  90 mTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAE---RARSyPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDA 166
Cdd:PRK13637  100 -TIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLDYedyKDKS-PFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDP 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 167 AVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYR 223
Cdd:PRK13637  178 KGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFK 234
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-230 1.73e-46

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 161.04  E-value: 1.73e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITtrPANRRPMGmvfqs 83
Cdd:COG4152     2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLD--PEDRRRIG----- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 Y-----ALFPHMTA-EQNVAFGlRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:COG4152    75 YlpeerGLYPKMKVgEQLVYLA-RLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLIL 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 158 DEPLSALDA-AVRVtLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRR--PRTVFV 230
Cdd:COG4152   154 DEPFSGLDPvNVEL-LKDVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQfgRNTLRL 227
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 22-284 1.78e-46

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 162.97  E-value: 1.78e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR------PANRRPMGMVFQSYALFPHMTAEQN 95
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSrkgiflPPEKRRIGYVFQEARLFPHLSVRGN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  96 VAFGLRlrRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREE 175
Cdd:TIGR02142  96 LRYGMK--RARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILPY 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 176 IRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAgFVGASTRLSARLERAVE----GR 251
Cdd:TIGR02142 174 LERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPWLA-REDQGSLIEGVVAEHDQhyglTA 252

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1424145480 252 CRLDGILLRVPPQPElSDGSAVLLVVRPELVTL 284
Cdd:TIGR02142 253 LRLGGGHLWVPENLG-PTGARLRLRVPARDVSL 284
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 6-195 5.93e-46

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 157.01  E-value: 5.93e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   6 LQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEE---ITTRPAN---RRPMGM 79
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQEtppLNSKKASkfrREKLGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:TIGR03608  81 LFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADE 160

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1424145480 160 PLSALDAAVrvtlREEIRRIQQQL---GMTVIYVTHDQE 195
Cdd:TIGR03608 161 PTGSLDPKN----RDEVLDLLLELndeGKTIIIVTHDPE 195
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 1-226 1.97e-45

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 156.30  E-value: 1.97e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP---M 77
Cdd:COG0410     1 MPMLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIArlgI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGLRLRRlPPALIRQRCEELLALV-GLAERARSYPHQLSGGQQQRVALARALAVEPKVLL 156
Cdd:COG0410    81 GYVPEGRRIFPSLTVEENLLLGAYARR-DRAEVRADLERVYELFpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLL 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 157 LDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:COG0410   160 LDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLADPE 228
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 4-221 4.45e-45

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 155.28  E-value: 4.45e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP---MGMV 80
Cdd:cd03224     1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERAragIGYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRlpPALIRQRCEELLALV-GLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:cd03224    81 PEGRRIFPELTVEENLLLGAYARR--RAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDE 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:cd03224   159 PSEGLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 4-212 6.48e-45

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 154.30  E-value: 6.48e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRPMGMVFQS 83
Cdd:cd03268     1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEALRRIGALIEA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPpaliRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:cd03268    81 PGFYPNLTARENLRLLARLLGIR----KKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNG 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1424145480 164 LDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:cd03268   157 LDPDGIKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGKL 204
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 4-212 1.15e-44

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 152.20  E-value: 1.15e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEI---TTRPANRRPMGMV 80
Cdd:cd03216     1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVsfaSPRDARRAGIAMV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 fqsyalfphmtaeqnvafglrlrrlppalirqrceellalvglaerarsypHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:cd03216    81 ---------------------------------------------------YQLSVGERQMVEIARALARNARLLILDEP 109

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:cd03216   110 TAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRV 160
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
4-239 1.74e-44

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 154.74  E-value: 1.74e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT-TRPAN--------- 73
Cdd:PRK10619    6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlVRDKDgqlkvadkn 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 -----RRPMGMVFQSYALFPHMTAEQNVAFG-LRLRRLPPALIRQRCEELLALVGLAERAR-SYPHQLSGGQQQRVALAR 146
Cdd:PRK10619   86 qlrllRTRLTMVFQHFNLWSHMTVLENVMEApIQVLGLSKQEARERAVKYLAKVGIDERAQgKYPVHLSGGQQQRVSIAR 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 147 ALAVEPKVLLLDEPLSALDAavrvTLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYR 223
Cdd:PRK10619  166 ALAMEPEVLLFDEPTSALDP----ELVGEVLRIMQQLaeeGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFG 241

                         250
                  ....*....|....*.
gi 1424145480 224 RPRTVFVAGFVGASTR 239
Cdd:PRK10619  242 NPQSPRLQQFLKGSLK 257
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 4-211 1.29e-43

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 150.89  E-value: 1.29e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRrpMGMVFQS 83
Cdd:cd03269     1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAARNR--IGYLPEE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMT-AEQNVAFGlRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:cd03269    79 RGLYPKMKvIDQLVYLA-QLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFS 157

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:cd03269   158 GLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGR 205
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
1-227 2.54e-43

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 151.91  E-value: 2.54e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSF---------GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP 71
Cdd:COG4167     2 SALLEVRNLSKTFkyrtglfrrQQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEYGD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  72 ANRRP--MGMVFQ--SYALFPHMTAEQNVAFGLRLR-RLPPALIRQRCEELLALVGL-AERARSYPHQLSGGQQQRVALA 145
Cdd:COG4167    82 YKYRCkhIRMIFQdpNTSLNPRLNIGQILEEPLRLNtDLTAEEREERIFATLRLVGLlPEHANFYPHMLSSGQKQRVALA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 146 RALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:COG4167   162 RALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVFANP 241


                  ..
gi 1424145480 226 RT 227
Cdd:COG4167   242 QH 243
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 5-210 4.53e-43

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 149.61  E-value: 4.53e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRpanRRPMGMVFQSY 84
Cdd:cd03235     1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKE---RKRIGYVPQRR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  85 AL---FPhMTAEQNVAFGL----RLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:cd03235    78 SIdrdFP-ISVRDVVLMGLyghkGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLL 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 158 DEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARG 210
Cdd:cd03235   157 DEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLLNRT 208
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 4-212 5.83e-43

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 156.73  E-value: 5.83e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT---TRPANRRPMGMV 80
Cdd:COG3845     6 LELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRirsPRDAIALGIGMV 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGL---RLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:COG3845    86 HQHFMLVPNLTVAENIVLGLeptKGGRLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARILIL 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 158 DEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:COG3845   166 DEPTAVLTPQEADELFEILRRLAAE-GKSIIFITHKLREVMAIADRVTVLRRGKV 219
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
4-220 1.77e-42

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 149.50  E-value: 1.77e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANR--RPMGMVF 81
Cdd:COG4559     2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWElaRRRAVLP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 QSYAL-FPhMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERA-RSYPhQLSGGQQQRVALARALA-------VEP 152
Cdd:COG4559    82 QHSSLaFP-FTVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAgRSYQ-TLSGGEQQRVQLARVLAqlwepvdGGP 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 153 KVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEE 220
Cdd:COG4559   160 RWLFLDEPTSALDLAHQHAVLRLARQLARR-GGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEE 226
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
4-221 6.80e-42

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 148.37  E-value: 6.80e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP-----ANRRPMG 78
Cdd:PRK11831    8 VDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSrsrlyTVRKRMS 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPHMTAEQNVAFGLRLR-RLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:PRK11831   88 MLFQSGALFTDMNVFDNVAYPLREHtQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMF 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 158 DEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK11831  168 DEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 18-222 4.99e-41

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 146.05  E-value: 4.99e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITtrPAN----RRPMGMVFQS-YALFPHMTA 92
Cdd:PRK13648   24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAIT--DDNfeklRKHIGIVFQNpDNQFVGSIV 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  93 EQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTL 172
Cdd:PRK13648  102 KYDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNL 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1424145480 173 REEIRRIQQQLGMTVIYVTHDQEEALAiSGRIAVMARGRLEQLGTPEEIY 222
Cdd:PRK13648  182 LDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIF 230
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 4-224 5.41e-41

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 153.84  E-value: 5.41e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTR--AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGM 79
Cdd:COG2274   474 IELENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPAslRRQIGV 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFpHMTAEQNVAFGLrlrrlpPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARAL 148
Cdd:COG2274   554 VLQDVFLF-SGTIRENITLGD------PDATDEEIIEAARLAGLHDFIEALPMgydtvvgeggsNLSGGQRQRLAIARAL 626

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 149 AVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQqlGMTVIYVTHDqEEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:COG2274   627 LRNPRILILDEATSALDAETEAIILENLRRLLK--GRTVIIIAHR-LSTIRLADRIIVLDKGRIVEDGTHEELLAR 699
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 5-221 5.58e-41

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 145.90  E-value: 5.58e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFG--KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMV 80
Cdd:PRK13632    9 KVENVSFSYPnsENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISkeNLKEIRKKIGII 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSY-ALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:PRK13632   89 FQNPdNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDE 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALaISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK13632  169 STSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGKPKEI 229
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
 4-212 1.07e-40

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 143.65  E-value: 1.07e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF--GK--TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP--- 76
Cdd:TIGR02211   2 LKCENLGKRYqeGKldTRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLSSNERAklr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  77 ---MGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:TIGR02211  82 nkkLGFIYQFHHLLPDFTALENVAMPLLIGKKSVKEAKERAYEMLEKVGLEHRINHRPSELSGGERQRVAIARALVNQPS 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISgRIAVMARGRL 212
Cdd:TIGR02211 162 LVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELAKKLD-RVLEMKDGQL 219
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 17-246 2.33e-40

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 145.88  E-value: 2.33e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  17 RAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEI-----TTRPANRRPMGMVFQS-YA-LFPH 89
Cdd:PRK11308   29 KALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLlkadpEAQKLLRQKIQIVFQNpYGsLNPR 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  90 MTAEQNVAFGLRLR-RLPPALIRQRCEELLALVGL-AERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAA 167
Cdd:PRK11308  109 KKVGQILEEPLLINtSLSAAERREKALAMMAKVGLrPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVS 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 168 VRVTLREEIRRIQQQLGMTVIYVTHDqeeaLAISGRIA----VMARGRLEQLGTPEEIYRRPRTVFVAGFVGASTRLSAR 243
Cdd:PRK11308  189 VQAQVLNLMMDLQQELGLSYVFISHD----LSVVEHIAdevmVMYLGRCVEKGTKEQIFNNPRHPYTQALLSATPRLNPD 264


                  ...
gi 1424145480 244 LER 246
Cdd:PRK11308  265 DRR 267
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 2-220 9.39e-40

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 142.22  E-value: 9.39e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   2 AFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP----ANRRpm 77
Cdd:PRK13548    1 AMLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSpaelARRR-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYAL-FPhMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAE-RARSYPhQLSGGQQQRVALARALA------ 149
Cdd:PRK13548   79 AVLPQHSSLsFP-FTVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHlAGRDYP-QLSGGEQQRVQLARVLAqlwepd 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 150 VEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEE 220
Cdd:PRK13548  157 GPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAE 227
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
18-222 1.32e-39

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 142.53  E-value: 1.32e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDqeEITTRPAN-----RRPMGMVFQSyalfP--HM 90
Cdd:PRK13633   25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVD--GLDTSDEEnlwdiRNKAGMVFQN----PdnQI 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  91 TA---EQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAA 167
Cdd:PRK13633   99 VAtivEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPS 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 168 VRVTLREEIRRIQQQLGMTVIYVTHDQEEAlAISGRIAVMARGRLEQLGTPEEIY 222
Cdd:PRK13633  179 GRREVVNTIKELNKKYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGTPKEIF 232
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 16-225 1.85e-39

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 142.47  E-value: 1.85e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  16 TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPM----GMVFQ--SYALF 87
Cdd:PRK13634   20 RRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITagKKNKKLKPLrkkvGIVFQfpEHQLF 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  88 PHmTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAE--RARSyPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALD 165
Cdd:PRK13634  100 EE-TVEKDICFGPMNFGVSEEDAKQKAREMIELVGLPEelLARS-PFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLD 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 166 AAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PRK13634  178 PKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP 237
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
 4-221 3.91e-39

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 140.10  E-value: 3.91e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP-MGMVF- 81
Cdd:TIGR04406   2 LVAENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLPMHERArLGIGYl 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 -QSYALFPHMTAEQNVAFGLRLR-RLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:TIGR04406  82 pQEASIFRKLTVEENIMAVLEIRkDLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDE 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:TIGR04406 162 PFAGVDPIAVGDIKKIIKHLKER-GIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEI 222
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 22-212 4.17e-39

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 140.71  E-value: 4.17e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT-----TRPANRRPMGMVFQ-SYALF-PHMTAEQ 94
Cdd:TIGR02769  30 VSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYqldrkQRRAFRRDVQLVFQdSPSAVnPRMTVRQ 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  95 NVAFGLR-LRRLPPALIRQRCEELLALVGL-AERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTL 172
Cdd:TIGR02769 110 IIGEPLRhLTSLDESEQKARIAELLDMVGLrSEDADKLPRQLSGGQLQRINIARALAVKPKLIVLDEAVSNLDMVLQAVI 189

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1424145480 173 REEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:TIGR02769 190 LELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQI 229
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 4-211 5.38e-39

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 137.51  E-value: 5.38e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFG--KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGM 79
Cdd:cd03228     1 IEFKNVSFSYPgrPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRdlDLESLRKNIAY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFpHMTAEQNVafglrlrrlppalirqrceellalvglaerarsyphqLSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:cd03228    81 VPQDPFLF-SGTIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILILDE 122

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQqlGMTVIYVTHDqEEALAISGRIAVMARGR 211
Cdd:cd03228   123 ATSALDPETEALILEALRALAK--GKTVIVIAHR-LSTIRDADRIIVLDDGR 171
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 4-228 8.12e-39

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 140.21  E-value: 8.12e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGK-TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN----RRPMG 78
Cdd:PRK13639    2 LETRDLKYSYPDgTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDKKSllevRKTVG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSY--ALF-PhmTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVL 155
Cdd:PRK13639   82 IVFQNPddQLFaP--TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEII 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 156 LLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTV 228
Cdd:PRK13639  160 VLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDIETI 231
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
14-224 1.12e-38

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 146.08  E-value: 1.12e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  14 GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFpHMT 91
Cdd:COG1132   351 GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLEslRRQIGVVPQDTFLF-SGT 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  92 AEQNVAFGLrlrrlPPALiRQRCEELLALVGLAERARSYPHQ-----------LSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:COG1132   430 IRENIRYGR-----PDAT-DEEVEEAAKAAQAHEFIEALPDGydtvvgergvnLSGGQRQRIAIARALLKDPPILILDEA 503

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQqlGMTVIYVTH--------DqeealaisgRIAVMARGRLEQLGTPEE------IYRR 224
Cdd:COG1132   504 TSALDTETEALIQEALERLMK--GRTTIVIAHrlstirnaD---------RILVLDDGRIVEQGTHEEllarggLYAR 570
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-211 1.43e-38

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 139.45  E-value: 1.43e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGK-----TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP-- 76
Cdd:COG1101     2 LELKNLSKTFNPgtvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAky 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  77 MGMVFQSYAL--FPHMTAEQNVAFGLR---LRRLPPALIRQRCE---ELLALV--GLAERARSYPHQLSGGQQQRVALAR 146
Cdd:COG1101    82 IGRVFQDPMMgtAPSMTIEENLALAYRrgkRRGLRRGLTKKRRElfrELLATLglGLENRLDTKVGLLSGGQRQALSLLM 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 147 ALAVEPKVLLLDEPLSALD--AAVRVTlrEEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:COG1101   162 ATLTKPKLLLLDEHTAALDpkTAALVL--ELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGR 226
cbiO PRK13640
energy-coupling factor transporter ATPase;
15-225 1.56e-38

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 139.94  E-value: 1.56e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  15 KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDA---GHILLDQEEITTRPA--NRRPMGMVFQSY-ALFP 88
Cdd:PRK13640   19 KKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDnpnSKITVDGITLTAKTVwdIREKVGIVFQNPdNQFV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  89 HMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAV 168
Cdd:PRK13640   99 GATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAG 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 169 RVTLREEIRRIQQQLGMTVIYVTHDQEEAlAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PRK13640  179 KEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIFSKV 234
cbiO PRK13644
energy-coupling factor transporter ATPase;
16-225 2.41e-38

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 138.97  E-value: 2.41e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  16 TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIL---LDQEEITTRPANRRPMGMVFQS-YALFPHMT 91
Cdd:PRK13644   15 TPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLvsgIDTGDFSKLQGIRKLVGIVFQNpETQFVGRT 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  92 AEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVT 171
Cdd:PRK13644   95 VEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIA 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 172 LREEIRRIQQQlGMTVIYVTHDQEEaLAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PRK13644  175 VLERIKKLHEK-GKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLSDV 226
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 4-223 5.22e-38

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 143.40  E-value: 5.22e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-----GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAG--HILLDQEEITT---RPAN 73
Cdd:TIGR03269 280 IKVRNVSKRYisvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGevNVRVGDEWVDMtkpGPDG 359

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 R----RPMGMVFQSYALFPHMTAEQNV--AFGLRLrrlPPALIRQRCEELLALVGLAE-RARS----YPHQLSGGQQQRV 142
Cdd:TIGR03269 360 RgrakRYIGILHQEYDLYPHRTVLDNLteAIGLEL---PDELARMKAVITLKMVGFDEeKAEEildkYPDELSEGERHRV 436

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 143 ALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIY 222
Cdd:TIGR03269 437 ALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIV 516


                  .
gi 1424145480 223 R 223
Cdd:TIGR03269 517 E 517
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 1-225 6.78e-38

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 138.01  E-value: 6.78e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPM 77
Cdd:PRK13652    1 MHLIETRDLCYSYsGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIRevRKFV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSY--ALFPhMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVL 155
Cdd:PRK13652   81 GLVFQNPddQIFS-PTVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVL 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 156 LLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PRK13652  160 VLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 1-221 1.87e-37

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 135.98  E-value: 1.87e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGH--ILLDQE-------EIttrp 71
Cdd:COG1119     1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNdvRLFGERrggedvwEL---- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  72 anRRPMGMVfqSYALF----PHMTAEQNVAFGL----RLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVA 143
Cdd:COG1119    77 --RKRIGLV--SPALQlrfpRDETVLDVVLSGFfdsiGLYREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVL 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 144 LARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:COG1119   153 IARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEV 230
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 17-226 1.94e-37

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 138.30  E-value: 1.94e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  17 RAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHI------LLDQEEITTRpANRRPMGMVFQS--YALFP 88
Cdd:PRK15079   35 KAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVawlgkdLLGMKDDEWR-AVRSDIQMIFQDplASLNP 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  89 HMTAEQNVAFGLRLRR--LPPALIRQRCEELLALVGLAERA-RSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALD 165
Cdd:PRK15079  114 RMTIGEIIAEPLRTYHpkLSRQEVKDRVKAMMLKVGLLPNLiNRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALD 193

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 166 AAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:PRK15079  194 VSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPL 254
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 4-224 2.45e-37

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 142.20  E-value: 2.45e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTR-AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMV 80
Cdd:COG4988   337 IELEDVSFSYPGGRpALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSdlDPASWRRQIAWV 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFpHMTAEQNVAFGLrlrrlpPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARALA 149
Cdd:COG4988   417 PQNPYLF-AGTIRENLRLGR------PDASDEELEAALEAAGLDEFVAALPDgldtplgeggrGLSGGQAQRLALARALL 489

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 150 VEPKVLLLDEPLSALDAAVRVTLREEIRRIQQqlGMTVIYVTHDqEEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:COG4988   490 RDAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHR-LALLAQADRILVLDDGRIVEQGTHEELLAK 561
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 4-225 3.65e-36

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 139.13  E-value: 3.65e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF--GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGM 79
Cdd:COG4987   334 LELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDdlRRRIAV 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFpHMTAEQNvafgLRLRRlpPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARAL 148
Cdd:COG4987   414 VPQRPHLF-DTTLREN----LRLAR--PDATDEELWAALERVGLGDWLAALPDgldtwlgeggrRLSGGERRRLALARAL 486

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 149 AVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQqlGMTVIYVTHDqEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:COG4987   487 LRDAPILLLDEPTEGLDAATEQALLADLLEALA--GRTVLLITHR-LAGLERMDRILVLEDGRIVEQGTHEELLAQN 560
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 2-196 6.60e-36

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 130.99  E-value: 6.60e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   2 AFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP--ANRRPMGM 79
Cdd:PRK10247    6 PLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKpeIYRQQVSY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHmTAEQNVAFGLRLRRLPPAliRQRCEELLALVGLAERARSYP-HQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:PRK10247   86 CAQTPTLFGD-TVYDNLIFPWQIRNQQPD--PAIFLDDLERFALPDTILTKNiAELSGGEKQRISLIRNLQFMPKVLLLD 162

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEE 196
Cdd:PRK10247  163 EITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDE 200
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 4-228 7.38e-36

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 132.04  E-value: 7.38e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANR-RPMGMV-- 80
Cdd:PRK11300    6 LSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQiARMGVVrt 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQN--VAFGLRLRR-------LPPALIRQRCEEL------LALVGLAERARSYPHQLSGGQQQRVALA 145
Cdd:PRK11300   86 FQHVRLFREMTVIENllVAQHQQLKTglfsgllKTPAFRRAESEALdraatwLERVGLLEHANRQAGNLAYGQQRRLEIA 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 146 RALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PRK11300  166 RCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRNNP 245


                  ...
gi 1424145480 226 RTV 228
Cdd:PRK11300  246 DVI 248
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 4-211 8.65e-36

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 131.02  E-value: 8.65e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF------GKTR-AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEE----ITTRPA 72
Cdd:COG4778     5 LEVENLSKTFtlhlqgGKRLpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGgwvdLAQASP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  73 N------RRPMGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAER-ARSYPHQLSGGQQQRVALA 145
Cdd:COG4778    85 ReilalrRRTIGYVSQFLRVIPRVSALDVVAEPLLERGVDREEARARARELLARLNLPERlWDLPPATFSGGEQQRVNIA 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 146 RALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:COG4778   165 RGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVVDVTPFS 229
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 1-221 1.34e-35

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 130.78  E-value: 1.34e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN---RRPM 77
Cdd:PRK10895    1 MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHaraRRGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGLRLRR-LPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLL 156
Cdd:PRK10895   81 GYLPQEASIFRRLSVYDNLMAVLQIRDdLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 157 LDEPLSALDAAVRVtlreEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK10895  161 LDEPFAGVDPISVI----DIKRIIEHLrdsGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEI 224
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 5-210 1.37e-35

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 129.68  E-value: 1.37e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGK-TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRpANRRPMGMVFQS 83
Cdd:cd03226     1 RIENISFSYKKgTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAK-ERRKSIGYVMQD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 --YALFphmtaEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPL 161
Cdd:cd03226    80 vdYQLF-----TDSVREELLLGLKELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPT 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1424145480 162 SALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARG 210
Cdd:cd03226   155 SGLDYKNMERVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANG 202
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
4-212 1.58e-35

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 129.99  E-value: 1.58e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-----PANRRPM 77
Cdd:PRK10908    2 IRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLknrevPFLRRQI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:PRK10908   82 GMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLA 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 158 DEPLSALDAAvrvtLREEIRRIQQQ---LGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:PRK10908  162 DEPTGNLDDA----LSEGILRLFEEfnrVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 4-221 1.48e-34

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 127.64  E-value: 1.48e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP---MGMV 80
Cdd:TIGR03410   1 LEVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERAragIAYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRrlpPALIRQRCEELLAL--VGLAERARSyPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:TIGR03410  81 PQGREIFPRLTVEENLLTGLAAL---PRRSRKIPDEIYELfpVLKEMLGRR-GGDLSGGQQQQLAIARALVTRPKLLLLD 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:TIGR03410 157 EPTEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
19-212 3.69e-34

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 127.88  E-value: 3.69e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  19 VERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-----RPANRRPMGMVFQSY--ALFPHMT 91
Cdd:PRK10419   28 LNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKlnraqRKAFRRDIQMVFQDSisAVNPRKT 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  92 AEQNVAFGLR-LRRLPPALIRQRCEELLALVGLA-ERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVR 169
Cdd:PRK10419  108 VREIIREPLRhLLSLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQ 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1424145480 170 VTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:PRK10419  188 AGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQI 230
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 16-219 8.40e-34

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 126.77  E-value: 8.40e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  16 TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSY--ALFPhMT 91
Cdd:PRK13647   18 TKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKwvRSKVGLVFQDPddQVFS-ST 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  92 AEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVT 171
Cdd:PRK13647   97 VWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQET 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1424145480 172 LREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPE 219
Cdd:PRK13647  177 LMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKS 223
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 5-221 1.16e-33

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 125.97  E-value: 1.16e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANR--RPMGMVFQ 82
Cdd:COG4604     3 EIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRElaKRLAILRQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGlrlR------RLPPAlIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLL 156
Cdd:COG4604    83 ENHINSRLTVRELVAFG---RfpyskgRLTAE-DREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVL 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 157 LDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:COG4604   159 LDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI 223
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 2-225 1.22e-33

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 126.04  E-value: 1.22e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   2 AFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLV--AGFEQPD---AGHILLDQEEITTRPAN--- 73
Cdd:PRK14239    4 PILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLNPEvtiTGSIVYNGHNIYSPRTDtvd 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 -RRPMGMVFQSYALFPhMTAEQNVAFGLRLRRLP-PALIRQRCEELLALVGLAERARSYPHQ----LSGGQQQRVALARA 147
Cdd:PRK14239   84 lRKEIGMVFQQPNPFP-MSIYENVVYGLRLKGIKdKQVLDEAVEKSLKGASIWDEVKDRLHDsalgLSGGQQQRVCIARV 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 148 LAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlgMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PRK14239  163 LATSPKIILLDEPTSALDPISAGKIEETLLGLKDD--YTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNP 238
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
 18-225 1.45e-33

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 125.17  E-value: 1.45e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDA----GHILLDQEEITTRPANRRPMGMVFQS--YALFPHMT 91
Cdd:TIGR02770   1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLtqtsGEILLDGRPLLPLSIRGRHIATIMQNprTAFNPLFT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  92 AEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERAR---SYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAV 168
Cdd:TIGR02770  81 MGNHAIETLRSLGKLSKQARALILEALEAVGLPDPEEvlkKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDLDVVN 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 169 RVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:TIGR02770 161 QARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNP 217
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
2-221 4.93e-33

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 125.69  E-value: 4.93e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   2 AFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-PANRRPMGMV 80
Cdd:PRK13537    6 APIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRaRHARQRVGVV 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:PRK13537   86 PQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEP 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK13537  166 TTGLDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHAL 225
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 9-235 8.05e-33

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 124.44  E-value: 8.05e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   9 LTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRL-------VAGFEQpdAGHILLDQEEITTRP---ANRRPMG 78
Cdd:PRK14271   27 LTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTlnrmndkVSGYRY--SGDVLLGGRSIFNYRdvlEFRRRVG 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPhMTAEQNVAFGLRLRRL-PPALIRQRCEELLALVGL----AERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:PRK14271  105 MLFQRPNPFP-MSIMDNVLAGVRAHKLvPRKEFRGVAQARLTEVGLwdavKDRLSDSPFRLSGGQQQLLCLARTLAVNPE 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQLgmTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTV----F 229
Cdd:PRK14271  184 VLLLDEPTSALDPTTTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAetarY 261


                  ....*.
gi 1424145480 230 VAGFVG 235
Cdd:PRK14271  262 VAGLSG 267
cbiO PRK13642
energy-coupling factor transporter ATPase;
4-222 8.25e-33

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 124.43  E-value: 8.25e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVER---ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPA--NRRPMG 78
Cdd:PRK13642    5 LEVENLVFKYEKESDVNQlngVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVwnLRRKIG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSY-ALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:PRK13642   85 MVFQNPdNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIIL 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 158 DEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEAlAISGRIAVMARGRLEQLGTPEEIY 222
Cdd:PRK13642  165 DESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEA-ASSDRILVMKAGEIIKEAAPSELF 228
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 1-226 8.28e-33

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 123.48  E-value: 8.28e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLR----LVAGFEQPD-AGHILLDQEEITTRPAN-- 73
Cdd:PRK14247    1 MNKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRvfnrLIELYPEARvSGEVYLDGQDIFKMDVIel 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 RRPMGMVFQSYALFPHMTAEQNVAFGLRLRRL--PPALIRQRCEELLALVGLAE----RARSYPHQLSGGQQQRVALARA 147
Cdd:PRK14247   81 RRRVQMVFQIPNPIPNLSIFENVALGLKLNRLvkSKKELQERVRWALEKAQLWDevkdRLDAPAGKLSGGQQQRLCIARA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 148 LAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlgMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:PRK14247  161 LAFQPEVLLADEPTANLDPENTAKIESLFLELKKD--MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPR 237
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 4-226 8.43e-33

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 123.80  E-value: 8.43e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQ--PDA---GHILLDQEEITTRPAN----R 74
Cdd:PRK14267    5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLElnEEArveGEVRLFGRNIYSPDVDpievR 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 RPMGMVFQSYALFPHMTAEQNVAFGLRLRRL--PPALIRQRCEELLALVGLAE----RARSYPHQLSGGQQQRVALARAL 148
Cdd:PRK14267   85 REVGMVFQYPNPFPHLTIYDNVAIGVKLNGLvkSKKELDERVEWALKKAALWDevkdRLNDYPSNLSGGQRQRLVIARAL 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 149 AVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLgmTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:PRK14267  165 AMKPKILLMDEPTANIDPVGTAKIEELLFELKKEY--TIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPE 240
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
2-197 1.27e-32

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 129.46  E-value: 1.27e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   2 AFLELQELTKSF----GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN---- 73
Cdd:PRK10535    3 ALLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADalaq 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 --RRPMGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVE 151
Cdd:PRK10535   83 lrREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNG 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1424145480 152 PKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEA 197
Cdd:PRK10535  163 GQVILADEPTGALDSHSGEEVMAILHQLRDR-GHTVIIVTHDPQVA 207
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
16-214 2.18e-32

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 121.85  E-value: 2.18e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  16 TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIL-----LDQEEITTRPANR-RPMGMVFQSYALFPH 89
Cdd:PRK11629   22 TDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIfngqpMSKLSSAAKAELRnQKLGFIYQFHHLLPD 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  90 MTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVR 169
Cdd:PRK11629  102 FTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNA 181

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1424145480 170 VTLREEIRRIQQQLGMTVIYVTHDQEEALAISgRIAVMARGRLEQ 214
Cdd:PRK11629  182 DSIFQLLGELNRLQGTAFLVVTHDLQLAKRMS-RQLEMRDGRLTA 225
cbiO PRK13649
energy-coupling factor transporter ATPase;
17-224 6.72e-32

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 122.16  E-value: 6.72e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  17 RAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN------RRPMGMVFQsyalFPHM 90
Cdd:PRK13649   21 RALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNkdikqiRKKVGLVFQ----FPES 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  91 -----TAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSY-PHQLSGGQQQRVALARALAVEPKVLLLDEPLSAL 164
Cdd:PRK13649   97 qlfeeTVLKDVAFGPQNFGVSQEEAEALAREKLALVGISESLFEKnPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGL 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 165 DAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:PRK13649  177 DPKGRKELMTLFKKLHQS-GMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
34-222 8.20e-32

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 123.45  E-value: 8.20e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  34 LLGPSGCGKTTVLRLVAGFEQPDAGHI------LLDQEEITTRPANRRPMGMVFQSYALFPHMTAEQNVAFGLRlrrlpp 107
Cdd:PRK11144   29 IFGRSGAGKTSLINAISGLTRPQKGRIvlngrvLFDAEKGICLPPEKRRIGYVFQDARLFPHYKVRGNLRYGMA------ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 108 ALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTV 187
Cdd:PRK11144  103 KSMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIPI 182

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1424145480 188 IYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIY 222
Cdd:PRK11144  183 LYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVW 217
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 4-212 1.47e-31

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 118.30  E-value: 1.47e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSfgktRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-PANRRPMGMVF- 81
Cdd:cd03215     5 LEVRGLSVK----GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRsPRDAIRAGIAYv 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 ----QSYALFPHMTAEQNVAFglrlrrlppalirqrceellalvglaerarsyPHQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:cd03215    81 pedrKREGLVLDLSVAENIAL--------------------------------SSLLSGGNQQKVVLARWLARDPRVLIL 128

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 158 DEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:cd03215   129 DEPTRGVDVGAKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
4-229 1.57e-31

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 120.12  E-value: 1.57e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRrpmgmVFQS 83
Cdd:PRK11231    3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQ-----LARR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFP--HMTAE-----QNVAFGL--------RLRRLPPALIRQRCEElLALVGLAERARSyphQLSGGQQQRVALARAL 148
Cdd:PRK11231   78 LALLPqhHLTPEgitvrELVAYGRspwlslwgRLSAEDNARVNQAMEQ-TRINHLADRRLT---DLSGGQRQRAFLAMVL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 149 AVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIY--RRPR 226
Cdd:PRK11231  154 AQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMtpGLLR 232


                  ...
gi 1424145480 227 TVF 229
Cdd:PRK11231  233 TVF 235
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 4-197 1.98e-31

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 119.11  E-value: 1.98e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVE----RGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-----RPANR 74
Cdd:PRK10584    7 VEVHHLKKSVGQGEHELSILTGVElvvkRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQmdeeaRAKLR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 -RPMGMVFQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:PRK10584   87 aKHVGFVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPD 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEA 197
Cdd:PRK10584  167 VLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLA 210
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 1-226 5.22e-31

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 122.26  E-value: 5.22e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANR--RPMG 78
Cdd:PRK09536    1 MPMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAasRRVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPHMTAEQNVAFGL-----RLRRLPPAlIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:PRK09536   81 SVPQDTSLSFEFDVRQVVEMGRtphrsRFDTWTET-DRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATP 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:PRK09536  160 VLLLDEPTASLDINHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADT 231
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 4-221 5.27e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 120.19  E-value: 5.27e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKT-----RAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHI--LLDQEEITTRPAN--- 73
Cdd:PRK13651    3 IKVKNIVKIFNKKlptelKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewIFKDEKNKKKTKEkek 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 ---------------------RRPMGMVFQ--SYALFpHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAER--AR 128
Cdd:PRK13651   83 vleklviqktrfkkikkikeiRRRVGVVFQfaEYQLF-EQTIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLDESylQR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 129 SyPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMA 208
Cdd:PRK13651  162 S-PFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLEWTKRTIFFK 239

                         250
                  ....*....|...
gi 1424145480 209 RGRLEQLGTPEEI 221
Cdd:PRK13651  240 DGKIIKDGDTYDI 252
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 18-226 8.18e-31

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 124.20  E-value: 8.18e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-----RRPMGMVFQS-YA-LFPHM 90
Cdd:PRK10261  339 AVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGklqalRRDIQFIFQDpYAsLDPRQ 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  91 TAEQNVAFGLRLRRLPPA-LIRQRCEELLALVGL-AERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAV 168
Cdd:PRK10261  419 TVGDSIMEPLRVHGLLPGkAAAARVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSI 498

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 169 RVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:PRK10261  499 RGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQ 556
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 23-220 1.51e-30

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 117.26  E-value: 1.51e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  23 SLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFPhMTAEQNVAFGl 100
Cdd:cd03249    23 SLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRwlRSQIGLVSQEPVLFD-GTIAENIRYG- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 101 rlrrLPPALIRQRcEELLALVGLAERARSYPH-----------QLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVr 169
Cdd:cd03249   101 ----KPDATDEEV-EEAAKKANIHDFIMSLPDgydtlvgergsQLSGGQKQRIAIARALLRNPKILLLDEATSALDAES- 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 170 vtlrEEIrrIQQQL-----GMTVIYVTHdqeEALAISG--RIAVMARGRLEQLGTPEE 220
Cdd:cd03249   175 ----EKL--VQEALdramkGRTTIVIAH---RLSTIRNadLIAVLQNGQVVEQGTHDE 223
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 4-192 3.90e-30

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 114.76  E-value: 3.90e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEI-TTRPANRRPMGMVFQ 82
Cdd:TIGR01189   1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLaEQRDEPHENILYLGH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPpaliRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:TIGR01189  81 LPGLKPELSALENLHFWAAIHGGA----QRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTT 156

                         170       180       190
                  ....*....|....*....|....*....|
gi 1424145480 163 ALDAAvRVTLREEIRRIQQQLGMTVIYVTH 192
Cdd:TIGR01189 157 ALDKA-GVALLAGLLRAHLARGGIVLLTTH 185
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 1-226 4.27e-30

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 118.31  E-value: 4.27e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKT----RAVERISLGVERGEFLTLLGPSGCGKT-TVLRLVAGFEQPD---AGHILLDQEEITTRPA 72
Cdd:PRK11022    1 MALLNVDKLSVHFGDEsapfRAVDRISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYPGrvmAEKLEFNGQDLQRISE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  73 NRR------PMGMVFQ--------SYAL-FPHMTAEQNVAFGLRLRRlppaliRQRCEELLALVGL---AERARSYPHQL 134
Cdd:PRK11022   81 KERrnlvgaEVAMIFQdpmtslnpCYTVgFQIMEAIKVHQGGNKKTR------RQRAIDLLNQVGIpdpASRLDVYPHQL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 135 SGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQ 214
Cdd:PRK11022  155 SGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVE 234

                         250
                  ....*....|..
gi 1424145480 215 LGTPEEIYRRPR 226
Cdd:PRK11022  235 TGKAHDIFRAPR 246
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 4-222 4.66e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 117.26  E-value: 4.66e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGK-TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN----RRPMG 78
Cdd:PRK13636    6 LKVEELNYNYSDgTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDYSRKGlmklRESVG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQS--YALFPhMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLL 156
Cdd:PRK13636   86 MVFQDpdNQLFS-ASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLV 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 157 LDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIY 222
Cdd:PRK13636  165 LDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
4-212 5.21e-30

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 120.89  E-value: 5.21e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKsfgkTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-PANRRPMGMVF- 81
Cdd:COG1129   257 LEVEGLSV----GGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRsPRDAIRAGIAYv 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 ----QSYALFPHMTAEQNVAFGL-----RLRRLPPALIRQRCEELLALVGLaeRARSyPHQ----LSGGQQQRVALARAL 148
Cdd:COG1129   333 pedrKGEGLVLDLSIRENITLASldrlsRGGLLDRRRERALAEEYIKRLRI--KTPS-PEQpvgnLSGGNQQKVVLAKWL 409

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 149 AVEPKVLLLDEPLSALDAAVRVtlreEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:COG1129   410 ATDPKVLILDEPTRGIDVGAKA----EIYRLIRELaaeGKAVIVISSELPELLGLSDRILVMREGRI 472
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 4-212 8.24e-30

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 113.08  E-value: 8.24e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRA--VERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-RPANRRPM-GM 79
Cdd:cd03246     1 LEVENVSFRYPGAEPpvLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQwDPNELGDHvGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHMTAEqNVafglrlrrlppalirqrceellalvglaerarsyphqLSGGQQQRVALARALAVEPKVLLLDE 159
Cdd:cd03246    81 LPQDDELFSGSIAE-NI-------------------------------------LSGGQRQRLGLARALYGNPRILVLDE 122

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHdQEEALAISGRIAVMARGRL 212
Cdd:cd03246   123 PNSHLDVEGERALNQAIAALKAA-GATRIVIAH-RPETLASADRILVLEDGRV 173
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
4-212 9.59e-30

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 115.88  E-value: 9.59e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLR----LVAGFEQPDAGHILLDQE-EITTRPA-----N 73
Cdd:PRK09984    5 IRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRhlsgLITGDKSAGSHIELLGRTvQREGRLArdirkS 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 RRPMGMVFQSYALFPHMTAEQNVAFGLR---------LRRLPPALiRQRCEELLALVGLAERARSYPHQLSGGQQQRVAL 144
Cdd:PRK09984   85 RANTGYIFQQFNLVNRLSVLENVLIGALgstpfwrtcFSWFTREQ-KQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAI 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 145 ARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:PRK09984  164 ARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHV 231
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 15-212 1.04e-29

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 114.22  E-value: 1.04e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  15 KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFpHMTA 92
Cdd:cd03245    16 EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPAdlRRNIGYVPQDVTLF-YGTL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  93 EQNVAFGLrlrrlpPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARALAVEPKVLLLDEPL 161
Cdd:cd03245    95 RDNITLGA------PLADDERILRAAELAGVTDFVNKHPNgldlqigergrGLSGGQRQAVALARALLNDPPILLLDEPT 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 162 SALDAAVRVTLreeIRRIQQQL-GMTVIYVTHDQeEALAISGRIAVMARGRL 212
Cdd:cd03245   169 SAMDMNSEERL---KERLRQLLgDKTLIIITHRP-SLLDLVDRIIVMDSGRI 216
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 14-216 1.20e-29

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 114.17  E-value: 1.20e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  14 GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeEITTRPANRRPMGMVFQsyalfPHMTAE 93
Cdd:cd03220    33 GEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTV-----TVRGRVSSLLGLGGGFN-----PELTGR 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  94 QNVAFGLRLRRLPPALIRQRCEELLALVGLAE----RARSYphqlSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVR 169
Cdd:cd03220   103 ENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDfidlPVKTY----SSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQ 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1424145480 170 VTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLG 216
Cdd:cd03220   179 EKCQRRLRELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 4-226 2.02e-29

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 114.88  E-value: 2.02e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLR-------LVAGFEQPDA----GHILLDQEeitTRPA 72
Cdd:PRK14243   11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRcfnrlndLIPGFRVEGKvtfhGKNLYAPD---VDPV 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  73 N-RRPMGMVFQSYALFPHMTAEqNVAFGLRL------------RRLPPALIRQRCEELLALVGLAerarsyphqLSGGQQ 139
Cdd:PRK14243   88 EvRRRIGMVFQKPNPFPKSIYD-NIAYGARIngykgdmdelveRSLRQAALWDEVKDKLKQSGLS---------LSGGQQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 140 QRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlgMTVIYVTHDQEEALAISGRIAVMA---------RG 210
Cdd:PRK14243  158 QRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQ--YTIIIVTHNMQQAARVSDMTAFFNveltegggrYG 235

                         250
                  ....*....|....*.
gi 1424145480 211 RLEQLGTPEEIYRRPR 226
Cdd:PRK14243  236 YLVEFDRTEKIFNSPQ 251
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 15-221 2.03e-29

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 120.36  E-value: 2.03e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  15 KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-RPAN-RRPMGMVFQSYALFpHMTA 92
Cdd:TIGR03375 477 ETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQiDPADlRRNIGYVPQDPRLF-YGTL 555

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  93 EQNVAFGLrlrrlpPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARALAVEPKVLLLDEPL 161
Cdd:TIGR03375 556 RDNIALGA------PYADDEEILRAAELAGVTEFVRRHPDgldmqigergrSLSGGQRQAVALARALLRDPPILLLDEPT 629

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 162 SALDAAVRVTLREEIRRIQQqlGMTVIYVTHDQeEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:TIGR03375 630 SAMDNRSEERFKDRLKRWLA--GKTLVLVTHRT-SLLDLVDRIIVMDNGRIVADGPKDQV 686
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
3-192 3.45e-29

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 112.59  E-value: 3.45e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   3 FLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-RPANRRPMGMVF 81
Cdd:PRK13538    1 MLEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRqRDEYHQDLLYLG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 QSYALFPHMTAEQNVAFGLRLRRLppaLIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPL 161
Cdd:PRK13538   81 HQPGIKTELTALENLRFYQRLHGP---GDDEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPF 157

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1424145480 162 SALDAAVRVTLREEIRRIQQQLGMtVIYVTH 192
Cdd:PRK13538  158 TAIDKQGVARLEALLAQHAEQGGM-VILTTH 187
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 11-224 3.99e-29

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 113.64  E-value: 3.99e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  11 KSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHI--------LLDqeeittrpanrrpMGMVFQ 82
Cdd:COG1134    34 TRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVevngrvsaLLE-------------LGAGFH 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 syalfPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERA----RSYphqlSGGQQQRVALARALAVEPKVLLLD 158
Cdd:COG1134   101 -----PELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIdqpvKTY----SSGMRARLAFAVATAVDPDILLVD 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:COG1134   172 EVLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAA 236
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 19-234 4.12e-29

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 113.99  E-value: 4.12e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  19 VERISLGVERGEFLTLLGPSGCGKTTVL----RLVAGFEQPDA--GHILLDQEEITTRPAN--RRPMGMVFQSYALFPHM 90
Cdd:PRK14246   26 LKDITIKIPNNSIFGIMGPSGSGKSTLLkvlnRLIEIYDSKIKvdGKVLYFGKDIFQIDAIklRKEVGMVFQQPNPFPHL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  91 TAEQNVAFGLRLRRLPPAL-IRQRCEELLALVGL----AERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALD 165
Cdd:PRK14246  106 SIYDNIAYPLKSHGIKEKReIKKIVEECLRKVGLwkevYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSMID 185

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 166 AAVRVTLREEIRRIQQQlgMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGFV 234
Cdd:PRK14246  186 IVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEKYV 252
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 4-225 4.82e-29

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 113.98  E-value: 4.82e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDA-----GHILLDQEEITTRPAN----R 74
Cdd:PRK14258    8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrveGRVEFFNQNIYERRVNlnrlR 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 RPMGMVFQSYALFPhMTAEQNVAFGLRLRRLPPAL-IRQRCEELLALVGLAERARSYPHQ----LSGGQQQRVALARALA 149
Cdd:PRK14258   88 RQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWRPKLeIDDIVESALKDADLWDEIKHKIHKsaldLSGGQQQRLCIARALA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 150 VEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMAR-----GRLEQLGTPEEIYRR 224
Cdd:PRK14258  167 VKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKKIFNS 246


                  .
gi 1424145480 225 P 225
Cdd:PRK14258  247 P 247
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 17-212 6.80e-29

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 112.81  E-value: 6.80e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  17 RAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHI-LLDQEEITTRPANRRPMGMVF-QSYALFPHMTAEQ 94
Cdd:cd03267    35 EALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVrVAGLVPWKRRKKFLRRIGVVFgQKTQLWWDLPVID 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  95 NVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLRE 174
Cdd:cd03267   115 SFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRN 194

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1424145480 175 EIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:cd03267   195 FLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRL 232
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 4-222 1.03e-28

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 111.94  E-value: 1.03e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTR--AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGM 79
Cdd:cd03251     1 VEFKNVTFRYPGDGppVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRdyTLASLRRQIGL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFpHMTAEQNVAFGLrlrrlpPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARAL 148
Cdd:cd03251    81 VSQDVFLF-NDTVAENIAYGR------PGATREEVEEAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAIARAL 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 149 AVEPKVLLLDEPLSALDAavrvtlrEEIRRIQQQL-----GMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEIY 222
Cdd:cd03251   154 LKDPPILILDEATSALDT-------ESERLVQAALerlmkNRTTFVIAH-RLSTIENADRIVVLEDGKIVERGTHEELL 224
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 12-220 1.11e-28

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 111.93  E-value: 1.11e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  12 SFGKTRAVER-ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFP 88
Cdd:cd03254    11 SYDEKKPVLKdINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKslRSMIGVVLQDTFLFS 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  89 HMTAEqNVAFGlrlRRLPPaliRQRCEELLALVGLAERARSYP-----------HQLSGGQQQRVALARALAVEPKVLLL 157
Cdd:cd03254    91 GTIME-NIRLG---RPNAT---DEEVIEAAKEAGAHDFIMKLPngydtvlgengGNLSQGERQLLAIARAMLRDPKILIL 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 158 DEPLSALDAAVRVTLREEIRRIQQqlGMTVIYVTHdqeeALAI---SGRIAVMARGRLEQLGTPEE 220
Cdd:cd03254   164 DEATSNIDTETEKLIQEALEKLMK--GRTSIIIAH----RLSTiknADKILVLDDGKIIEEGTHDE 223
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
4-225 3.87e-28

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 111.42  E-value: 3.87e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF---------GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANR 74
Cdd:PRK15112    5 LEVRNLSKTFryrtgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSY 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 RP--MGMVFQ--SYALFPHMTAEQNVAFGLRLR-RLPPALIRQRCEELLALVGL-AERARSYPHQLSGGQQQRVALARAL 148
Cdd:PRK15112   85 RSqrIRMIFQdpSTSLNPRQRISQILDFPLRLNtDLEPEQREKQIIETLRQVGLlPDHASYYPHMLAPGQKQRLGLARAL 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 149 AVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PRK15112  165 ILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASP 241
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
4-221 4.65e-28

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 113.00  E-value: 4.65e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP-ANRRPMGMVFQ 82
Cdd:PRK13536   42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARArLARARIGVVPQ 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:PRK13536  122 FDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTT 201

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK13536  202 GLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 22-224 5.43e-28

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 115.62  E-value: 5.43e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMVFQSYALFPHmTAEQNVAfg 99
Cdd:COG4618   351 VSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSqwDREELGRHIGYLPQDVELFDG-TIAENIA-- 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 100 lRLRRLPPALIrqrcEELLALVGLAERARSYP-----------HQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAV 168
Cdd:COG4618   428 -RFGDADPEKV----VAAAKLAGVHEMILRLPdgydtrigeggARLSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEG 502

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 169 RVTLREEIRRIQQQlGMTVIYVTHDQeEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:COG4618   503 EAALAAAIRALKAR-GATVVVITHRP-SLLAAVDKLLVLRDGRVQAFGPRDEVLAR 556
cbiO PRK13646
energy-coupling factor transporter ATPase;
18-223 7.62e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 111.02  E-value: 7.62e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN------RRPMGMVFQsyalFPHM- 90
Cdd:PRK13646   22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDkyirpvRKRIGMVFQ----FPESq 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  91 ----TAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSY-PHQLSGGQQQRVALARALAVEPKVLLLDEPLSALD 165
Cdd:PRK13646   98 lfedTVEREIIFGPKNFKMNLDEVKNYAHRLLMDLGFSRDVMSQsPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLD 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 166 AAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYR 223
Cdd:PRK13646  178 PQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFK 235
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 18-224 1.11e-27

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 109.50  E-value: 1.11e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFPHMTAEqN 95
Cdd:cd03252    17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAwlRRQVGVVLQENVLFNRSIRD-N 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  96 VAFGlrlrrlPPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARALAVEPKVLLLDEPLSAL 164
Cdd:cd03252    96 IALA------DPGMSMERVIEAAKLAGAHDFISELPEgydtivgeqgaGLSGGQRQRIAIARALIHNPRILIFDEATSAL 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 165 DAAVRVTLREEIRRIQQqlGMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:cd03252   170 DYESEHAIMRNMHDICA--GRTVIIIAH-RLSTVKNADRIIVMEKGRIVEQGSHDELLAE 226
cbiO PRK13645
energy-coupling factor transporter ATPase;
17-222 1.66e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 110.10  E-value: 1.66e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  17 RAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIttrPAN----------RRPMGMVFQ--SY 84
Cdd:PRK13645   25 KALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAI---PANlkkikevkrlRKEIGLVFQfpEY 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  85 ALFPHmTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAER-ARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:PRK13645  102 QLFQE-TIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLPEDyVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGG 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 164 LDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIY 222
Cdd:PRK13645  181 LDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 4-211 1.83e-27

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 113.49  E-value: 1.83e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAG------FEqpdaGHILLDQEEI---TTRPANR 74
Cdd:PRK13549    6 LEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGvyphgtYE----GEIIFEGEELqasNIRDTER 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 RPMGMVFQSYALFPHMTAEQNVAFG---LRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVE 151
Cdd:PRK13549   82 AGIAIIHQELALVKELSVLENIFLGneiTPGGIMDYDAMYLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQ 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 152 PKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:PRK13549  162 ARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGR 220
NHLM_micro_ABC2 TIGR03797
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...
 20-225 2.41e-27

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274789 [Multi-domain]  Cd Length: 686  Bit Score: 114.28  E-value: 2.41e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  20 ERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT--RPANRRPMGMVFQSYALFPHmTAEQNVA 97
Cdd:TIGR03797 470 DDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDGQDLAGldVQAVRRQLGVVLQNGRLMSG-SIFENIA 548

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  98 FGLRLRrlppaliRQRCEELLALVGLAERARSYPHQ-----------LSGGQQQRVALARALAVEPKVLLLDEPLSALD- 165
Cdd:TIGR03797 549 GGAPLT-------LDEAWEAARMAGLAEDIRAMPMGmhtvisegggtLSGGQRQRLLIARALVRKPRILLFDEATSALDn 621

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 166 ---AAVRVTLreeirriqQQLGMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:TIGR03797 622 rtqAIVSESL--------ERLKVTRIVIAH-RLSTIRNADRIYVLDAGRVVQQGTYDELMARE 675
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
12-199 4.25e-27

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 106.55  E-value: 4.25e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  12 SFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeeitTRPANRRPmGMVFQSYAL---FP 88
Cdd:NF040873    1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV--------RRAGGARV-AYVPQRSEVpdsLP 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  89 hMTAEQNVAFGL----RLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSAL 164
Cdd:NF040873   72 -LTVRDLVAMGRwarrGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGL 150

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1424145480 165 DAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALA 199
Cdd:NF040873  151 DAESRERIIALLAEEHAR-GATVVVVTHDLELVRR 184
cbiO PRK13643
energy-coupling factor transporter ATPase;
16-223 6.26e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 108.67  E-value: 6.26e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  16 TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN------RRPMGMVFQsyalFPH 89
Cdd:PRK13643   19 SRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQkeikpvRKKVGVVFQ----FPE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  90 M-----TAEQNVAFGLRLRRLPPALIRQRCEELLALVGLA-ERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:PRK13643   95 SqlfeeTVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLAdEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAG 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 164 LDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYR 223
Cdd:PRK13643  175 LDPKARIEMMQLFESIHQS-GQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQ 233
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
2-221 1.00e-26

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 107.38  E-value: 1.00e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   2 AFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEI---TTRPANRRpMG 78
Cdd:PRK10253    6 ARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIqhyASKEVARR-IG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPHMTAEQNVAFGlrlrRLP--PALIRQRCEELLAL------VGLAERARSYPHQLSGGQQQRVALARALAV 150
Cdd:PRK10253   85 LLAQNATTPGDITVQELVARG----RYPhqPLFTRWRKEDEEAVtkamqaTGITHLADQSVDTLSGGQRQRAWIAMVLAQ 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 151 EPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK10253  161 ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 4-195 1.49e-26

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 111.22  E-value: 1.49e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMV 80
Cdd:TIGR02857 322 LEFSGVSVAYpGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADswRDQIAWV 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPhmtaeQNVAFGLRLRRL--PPALIRqrceELLALVGLAERARSYP-----------HQLSGGQQQRVALARA 147
Cdd:TIGR02857 402 PQHPFLFA-----GTIAENIRLARPdaSDAEIR----EALERAGLDEFVAALPqgldtpigeggAGLSGGQAQRLALARA 472

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1424145480 148 LAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQqlGMTVIYVTHDQE 195
Cdd:TIGR02857 473 FLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLA 518
cbiO PRK13641
energy-coupling factor transporter ATPase;
15-225 1.87e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 107.22  E-value: 1.87e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  15 KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN------RRPMGMVFQsyalFP 88
Cdd:PRK13641   19 EKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNknlkklRKKVSLVFQ----FP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  89 HM-----TAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAER-ARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:PRK13641   95 EAqlfenTVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSEDlISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 163 ALDAAVRVTLReEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PRK13641  175 GLDPEGRKEMM-QLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDK 236
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 22-220 1.96e-26

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 105.78  E-value: 1.96e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMVFQSYALFpHMTAEQNVAFG 99
Cdd:cd03253    20 VSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIRevTLDSLRRAIGVVPQDTVLF-NDTIGYNIRYG 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 100 lRLRRLPPALIR-----QRCEELLAL-------VGlaERARsyphQLSGGQQQRVALARALAVEPKVLLLDEPLSALDaa 167
Cdd:cd03253    99 -RPDATDEEVIEaakaaQIHDKIMRFpdgydtiVG--ERGL----KLSGGEKQRVAIARAILKNPPILLLDEATSALD-- 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 168 vrvTLREeiRRIQQQL-----GMTVIYVTHDQEEaLAISGRIAVMARGRLEQLGTPEE 220
Cdd:cd03253   170 ---THTE--REIQAALrdvskGRTTIVIAHRLST-IVNADKIIVLKDGRIVERGTHEE 221
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 17-212 3.63e-26

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 107.10  E-value: 3.63e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  17 RAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLD----QEEittRPANRRPMGMVF-QSYALFPHMT 91
Cdd:COG4586    36 EAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLgyvpFKR---RKEFARRIGVVFgQRSQLWWDLP 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  92 AEQNvaFGL--RLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVR 169
Cdd:COG4586   113 AIDS--FRLlkAIYRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSK 190

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1424145480 170 VTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:COG4586   191 EAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHGRI 233
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 4-211 4.52e-26

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 105.39  E-value: 4.52e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP------ANRRPM 77
Cdd:PRK11701    7 LSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDlyalseAERRRL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 -----GMVFQSYA--LFPHMTAEQNVafGLRLRrlppAL-------IRQRCEELLALVGL-AERARSYPHQLSGGQQQRV 142
Cdd:PRK11701   87 lrtewGFVHQHPRdgLRMQVSAGGNI--GERLM----AVgarhygdIRATAGDWLERVEIdAARIDDLPTTFSGGMQQRL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 143 ALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:PRK11701  161 QIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGR 229
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 14-221 5.76e-26

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 109.36  E-value: 5.76e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  14 GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIttRPANR----RPMGMVFQSYALFPH 89
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADL--KQWDRetfgKHIGYLPQDVELFPG 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  90 mTAEQNVAfglRLRRLPPAlirQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:TIGR01842 407 -TVAENIA---RFGENADP---EKIIEAAKLAGVHELILRLPDgydtvigpggaTLSGGQRQRIALARALYGDPKLVVLD 479

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:TIGR01842 480 EPNSNLDEEGEQALANAIKALKAR-GITVVVITH-RPSLLGCVDKILVLQDGRIARFGERDEV 540
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
34-233 6.74e-26

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 105.47  E-value: 6.74e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  34 LLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP----ANRRPMGMVFQ--SYALFpHMTAEQNVAFGLRLRRLPP 107
Cdd:PRK13638   32 LVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKrgllALRQQVATVFQdpEQQIF-YTDIDSDIAFSLRNLGVPE 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 108 ALIRQRCEELLALVGlAERARSYPHQ-LSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMT 186
Cdd:PRK13638  111 AEITRRVDEALTLVD-AQHFRHQPIQcLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIRRIVAQ-GNH 188

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1424145480 187 VIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFVAGF 233
Cdd:PRK13638  189 VIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFACTEAMEQAGL 235
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 6-212 7.10e-26

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 109.00  E-value: 7.10e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   6 LQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeeitTRPANRRpMGMVFQSYA 85
Cdd:COG0488     1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEV--------SIPKGLR-IGYLPQEPP 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  86 LFPHMTAEQNVAFGL--------RLRRLPPAL------------------------IRQRCEELLALVGLAERARSYP-H 132
Cdd:COG0488    72 LDDDLTVLDTVLDGDaelraleaELEELEAKLaepdedlerlaelqeefealggweAEARAEEILSGLGFPEEDLDRPvS 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 133 QLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQqqlgMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:COG0488   152 ELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYP----GTVLVVSHDRYFLDRVATRILELDRGKL 227
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 14-242 1.39e-25

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 108.79  E-value: 1.39e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  14 GKTRAVERISLGVERGEFLTLLGPSGCGKT-TVLRLVAGFEQPDA----GHILL-----------DQEEITTRPANRRPM 77
Cdd:PRK10261   27 QKIAAVRNLSFSLQRGETLAIVGESGSGKSvTALALMRLLEQAGGlvqcDKMLLrrrsrqvielsEQSAAQMRHVRGADM 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQS--YALFPHMTAEQNVAFGLRLRRlppALIRQR----CEELLALVGLAERA---RSYPHQLSGGQQQRVALARAL 148
Cdd:PRK10261  107 AMIFQEpmTSLNPVFTVGEQIAESIRLHQ---GASREEamveAKRMLDQVRIPEAQtilSRYPHQLSGGMRQRVMIAMAL 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 149 AVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTV 228
Cdd:PRK10261  184 SCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHP 263

                         250
                  ....*....|....
gi 1424145480 229 FVAGFVGASTRLSA 242
Cdd:PRK10261  264 YTRALLAAVPQLGA 277
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-212 1.50e-25

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 103.42  E-value: 1.50e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN---RRPM 77
Cdd:PRK11614    3 KVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAkimREAV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFGLRLRRlpPALIRQRCEELLALVG-LAERARSYPHQLSGGQQQRVALARALAVEPKVLL 156
Cdd:PRK11614   83 AIVPEGRRVFSRMTVEENLAMGGFFAE--RDQFQERIKWVYELFPrLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLL 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 157 LDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:PRK11614  161 LDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHV 215
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 18-222 1.64e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 105.32  E-value: 1.64e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILL---------DQEEITTRPAN---------RRPMGM 79
Cdd:PRK13631   41 ALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiyigdkkNNHELITNPYSkkiknfkelRRRVSM 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQ--SYALFPHmTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAER--ARSyPHQLSGGQQQRVALARALAVEPKVL 155
Cdd:PRK13631  121 VFQfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDDSylERS-PFGLSGGQKRRVAIAGILAIQPEIL 198

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 156 LLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIY 222
Cdd:PRK13631  199 IFDEPTAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIF 264
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 4-211 1.70e-25

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 107.99  E-value: 1.70e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFeQPDA---GHILLDQEEITT---RPANRRPM 77
Cdd:TIGR02633   2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGV-YPHGtwdGEIYWSGSPLKAsniRDTERAGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTAEQNVAFG----LRLRRLPPALIRQRCEELLALVGLAERARSYP-HQLSGGQQQRVALARALAVEP 152
Cdd:TIGR02633  81 VIIHQELTLVPELSVAENIFLGneitLPGGRMAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQLVEIAKALNKQA 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 153 KVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:TIGR02633 161 RLLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQ 218
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 1-211 1.70e-25

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 108.25  E-value: 1.70e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSF---GKTR-AVERISLGVERGEFLTLLGPSGCGKT----TVLRLV----AGFEQPD---AGHILLDQE 65
Cdd:PRK15134    3 QPLLAIENLSVAFrqqQTVRtVVNDVSLQIEAGETLALVGESGSGKSvtalSILRLLpsppVVYPSGDirfHGESLLHAS 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  66 EITTRPANRRPMGMVFQS--YALFPHMTAEQNVAFGLRLRRlppALIRQ--RCEELLAL--VGL---AERARSYPHQLSG 136
Cdd:PRK15134   83 EQTLRGVRGNKIAMIFQEpmVSLNPLHTLEKQLYEVLSLHR---GMRREaaRGEILNCLdrVGIrqaAKRLTDYPHQLSG 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 137 GQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:PRK15134  160 GERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGR 234
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 4-212 1.96e-25

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 107.81  E-value: 1.96e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELT-KSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-PANRRPMGMVF 81
Cdd:COG3845   258 LEVENLSvRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLsPRERRRLGVAY 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 -----QSYALFPHMTAEQNVAFGlRLRRLP--------PALIRQRCEELLA-----LVGLAERARSyphqLSGGQQQRVA 143
Cdd:COG3845   338 ipedrLGRGLVPDMSVAENLILG-RYRRPPfsrggfldRKAIRAFAEELIEefdvrTPGPDTPARS----LSGGNQQKVI 412

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 144 LARALAVEPKVLLLDEPLSALD----AAVRVTLREEIRRiqqqlGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:COG3845   413 LARELSRDPKLLIAAQPTRGLDvgaiEFIHQRLLELRDA-----GAAVLLISEDLDEILALSDRIAVMYEGRI 480
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
1-212 5.48e-25

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 106.53  E-value: 5.48e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEI---TTRPANRRPM 77
Cdd:PRK11288    2 SPYLSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMrfaSTTAALAAGV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYALFPHMTaeqnVAFGLRLRRLPP-------ALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAV 150
Cdd:PRK11288   82 AIIYQELHLVPEMT----VAENLYLGQLPHkggivnrRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALAR 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 151 EPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:PRK11288  158 NARVIAFDEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRY 218
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 18-218 1.31e-24

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 106.64  E-value: 1.31e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-PANRRPMGMVFQSYALFPHMTAEQNV 96
Cdd:TIGR01257  945 AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNlDAVRQSLGMCPQHNILFHHLTVAEHI 1024

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   97 AFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEI 176
Cdd:TIGR01257 1025 LFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLL 1104

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1424145480  177 rrIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTP 218
Cdd:TIGR01257 1105 --LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 2-226 2.06e-24

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 100.68  E-value: 2.06e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   2 AFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQE-----EITTRP-ANRR 75
Cdd:TIGR02323   2 PLLQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRsgaelELYQLSeAERR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  76 PM-----GMVFQSYALFPHMTAEQNVAFGLRLRRLPP---ALIRQRCEELLALVGL-AERARSYPHQLSGGQQQRVALAR 146
Cdd:TIGR02323  82 RLmrtewGFVHQNPRDGLRMRVSAGANIGERLMAIGArhyGNIRATAQDWLEEVEIdPTRIDDLPRAFSGGMQQRLQIAR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 147 ALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:TIGR02323 162 NLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGLTDQVLDDPQ 241
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 9-226 2.11e-24

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 104.79  E-value: 2.11e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   9 LTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTT----VLRLVAGfeqpdAGHILLDQEEITTRPAN-----RRPMGM 79
Cdd:PRK15134  292 LKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLINS-----QGEIWFDGQPLHNLNRRqllpvRHRIQV 366

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQ--SYALFPHMTAEQNVAFGLRLRR--LPPALIRQRCEELLALVGLAERARS-YPHQLSGGQQQRVALARALAVEPKV 154
Cdd:PRK15134  367 VFQdpNSSLNPRLNVLQIIEEGLRVHQptLSAAQREQQVIAVMEEVGLDPETRHrYPAEFSGGQRQRIAIARALILKPSL 446

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 155 LLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:PRK15134  447 IILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQ 518
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 14-212 4.34e-24

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 98.39  E-value: 4.34e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  14 GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAG--FEQPDAGHILLDqeEITTRPAN-RRPMGMVFQSYALFPHM 90
Cdd:cd03213    20 SGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLIN--GRPLDKRSfRKIIGYVPQDDILHPTL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  91 TAEQNVAFGLRLRrlppalirqrceellalvglaerarsyphQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRV 170
Cdd:cd03213    98 TVRETLMFAAKLR-----------------------------GLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSAL 148

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1424145480 171 TLREEIRRIQQQlGMTVIYVTHD-QEEALAISGRIAVMARGRL 212
Cdd:cd03213   149 QVMSLLRRLADT-GRTIICSIHQpSSEIFELFDKLLLLSQGRV 190
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 22-216 6.29e-24

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 98.88  E-value: 6.29e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDA---GHILLDQEEITtRPANRRPMGMVFQSYALFPHMTAEQNVAF 98
Cdd:cd03234    26 VSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGttsGQILFNGQPRK-PDQFQKCVAYVRQDDILLPGLTVRETLTY 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  99 G--LRLRRLPPALIRQRCEE--LLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDA----AVRV 170
Cdd:cd03234   105 TaiLRLPRKSSDAIRKKRVEdvLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSftalNLVS 184

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1424145480 171 TLREEIRRiqqqlGMTVIYVTHD-QEEALAISGRIAVMARGRLEQLG 216
Cdd:cd03234   185 TLSQLARR-----NRIVILTIHQpRSDLFRLFDRILLLSSGEIVYSG 226
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
5-224 1.07e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 103.28  E-value: 1.07e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP-ANRRPMGMVFQS 83
Cdd:NF033858  268 EARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGDiATRRRVGYMSQA 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:NF033858  348 FSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSG 427

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 164 LDAAVR-------VTL-REEirriqqqlGMTVIYVTHDQEEAlAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:NF033858  428 VDPVARdmfwrllIELsRED--------GVTIFISTHFMNEA-ERCDRISLMHAGRVLASDTPAALVAA 487
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 4-221 1.10e-23

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 102.57  E-value: 1.10e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQ--PDAGHIL-------------------- 61
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyePTSGRIIyhvalcekcgyverpskvge 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  62 --------LDQEEI-------TTRPANRRPMGMVFQ-SYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAE 125
Cdd:TIGR03269  81 pcpvcggtLEPEEVdfwnlsdKLRRRIRKRIAIMLQrTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEMVQLSH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 126 RARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIA 205
Cdd:TIGR03269 161 RITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAI 240

                         250
                  ....*....|....*.
gi 1424145480 206 VMARGRLEQLGTPEEI 221
Cdd:TIGR03269 241 WLENGEIKEEGTPDEV 256
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 22-225 1.82e-23

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 102.49  E-value: 1.82e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFPHmTAEQNVAFG 99
Cdd:TIGR00958 500 LTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHylHRQVALVGQEPVLFSG-SVRENIAYG 578

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 100 LRlrRLPPALIRQRCEELLALVGLAERARSY-----PH--QLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTL 172
Cdd:TIGR00958 579 LT--DTPDEEIMAAAKAANAHDFIMEFPNGYdtevgEKgsQLSGGQKQRIAIARALVRKPRVLILDEATSALDAECEQLL 656

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 173 REEirriQQQLGMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:TIGR00958 657 QES----RSRASRTVLLIAH-RLSTVERADQILVLKKGSVVEMGTHKQLMEDQ 704
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 6-237 2.19e-23

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 97.88  E-value: 2.19e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   6 LQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILldqeeittRPANRRpMGMVFQSYA 85
Cdd:PRK09544    7 LENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK--------RNGKLR-IGYVPQKLY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  86 LFPhmTAEQNVAFGLRLR------RLPPALIRQRCEELLalvglaerarSYPHQ-LSGGQQQRVALARALAVEPKVLLLD 158
Cdd:PRK09544   78 LDT--TLPLTVNRFLRLRpgtkkeDILPALKRVQAGHLI----------DAPMQkLSGGETQRVLLARALLNRPQLLVLD 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHD-------QEEALAISGRIAVMargrleqlGTPEEIYRRPRTVFVA 231
Cdd:PRK09544  146 EPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDlhlvmakTDEVLCLNHHICCS--------GTPEVVSLHPEFISMF 217


                  ....*.
gi 1424145480 232 GFVGAS 237
Cdd:PRK09544  218 GPRGAE 223
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 4-192 2.47e-23

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 96.41  E-value: 2.47e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT-TRPANRRPMGMVFQ 82
Cdd:cd03231     1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDfQRDSIARGLLYLGH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNvafglrLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLS 162
Cdd:cd03231    81 APGIKTTLSVLEN------LRFWHADHSDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTT 154

                         170       180       190
                  ....*....|....*....|....*....|
gi 1424145480 163 ALDAAVRVTLREEIRRIQQQLGMtVIYVTH 192
Cdd:cd03231   155 ALDKAGVARFAEAMAGHCARGGM-VVLTTH 183
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
22-223 5.51e-23

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 97.17  E-value: 5.51e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT--RPANRRPMGMVFQSYALFPHMTAEQNVAFG 99
Cdd:PRK10575   30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwsSKAFARKVAYLPQQLPAAEGMTVRELVAIG 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 100 lrlrRLP--------PALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVT 171
Cdd:PRK10575  110 ----RYPwhgalgrfGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVD 185

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 172 LREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYR 223
Cdd:PRK10575  186 VLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMR 237
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 4-216 6.00e-23

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 94.69  E-value: 6.00e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFG--KTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRRP-MGMV 80
Cdd:cd03247     1 LSINNVSFSYPeqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSlISVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFpHMTAEQNVafGLRLrrlppalirqrceellalvglaerarsyphqlSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:cd03247    81 NQRPYLF-DTTLRNNL--GRRF--------------------------------SGGERQRLALARILLQDAPIVLLDEP 125

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 161 LSALDaavRVTLREEIRRIQQQL-GMTVIYVTHdQEEALAISGRIAVMARGRLEQLG 216
Cdd:cd03247   126 TVGLD---PITERQLLSLIFEVLkDKTLIWITH-HLTGIEHMDKILFLENGKIIMQG 178
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 20-192 6.92e-23

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 95.33  E-value: 6.92e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  20 ERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTrPANRRPMGMVFQSYALFPHMTAEQNVAFG 99
Cdd:PRK13539   19 SGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDD-PDVAEACHYLGHRNAMKPALTVAENLEFW 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 100 LRLRRLPPALIrqrcEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRI 179
Cdd:PRK13539   98 AAFLGGEELDI----AAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRAH 173

                         170
                  ....*....|...
gi 1424145480 180 QQQLGMtVIYVTH 192
Cdd:PRK13539  174 LAQGGI-VIAATH 185
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 4-195 1.16e-22

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 92.90  E-value: 1.16e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeeitTRPANRRPmgmvfqs 83
Cdd:cd03221     1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV--------TWGSTVKI------- 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 yalfphmtaeqnvafglrlrrlppalirqrceellalvglaerarSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:cd03221    66 ---------------------------------------------GYFEQLSGGEKMRLALAKLLLENPNLLLLDEPTNH 100

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1424145480 164 LDAAVRVTLREEIRRIQQqlgmTVIYVTHDQE 195
Cdd:cd03221   101 LDLESIEALEEALKEYPG----TVILVSHDRY 128
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
3-210 1.38e-22

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 99.47  E-value: 1.38e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   3 FLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEE---ITTRPANRRPMGM 79
Cdd:PRK09700    5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINynkLDHKLAAQLGIGI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHMTAEQNVAFGlrlrRLPP-----------ALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARAL 148
Cdd:PRK09700   85 IYQELSVIDELTVLENLYIG----RHLTkkvcgvniidwREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 149 AVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARG 210
Cdd:PRK09700  161 MLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDG 221
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 18-221 3.77e-22

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 98.25  E-value: 3.77e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMVFQSYALFPHMTAEqN 95
Cdd:TIGR02203 347 ALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLAdyTLASLRRQVALVSQDVVLFNDTIAN-N 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  96 VAFGlRLRRLPPALIRQRCEE--LLALV-----GLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAav 168
Cdd:TIGR02203 426 IAYG-RTEQADRAEIERALAAayAQDFVdklplGLDTPIGENGVLLSGGQRQRLAIARALLKDAPILILDEATSALDN-- 502

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 169 rvtlrEEIRRIQQQL-----GMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:TIGR02203 503 -----ESERLVQAALerlmqGRTTLVIAH-RLSTIEKADRIVVMDDGRIVERGTHNEL 554
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
1-225 4.03e-22

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 96.13  E-value: 4.03e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSF----GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFeQPDAGHI------LLDQEEITTR 70
Cdd:COG4170     1 MPLLDIRNLTIEIdtpqGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGI-TKDNWHVtadrfrWNGIDLLKLS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  71 PANRRP-----MGMVFQ--SYALFPHMTAEQNVAFGLRLRRLP------PALIRQRCEELLALVGLAERA---RSYPHQL 134
Cdd:COG4170    80 PRERRKiigreIAMIFQepSSCLDPSAKIGDQLIEAIPSWTFKgkwwqrFKWRKKRAIELLHRVGIKDHKdimNSYPHEL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 135 SGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQ 214
Cdd:COG4170   160 TEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVE 239

                         250
                  ....*....|.
gi 1424145480 215 LGTPEEIYRRP 225
Cdd:COG4170   240 SGPTEQILKSP 250
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 1-242 9.05e-22

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 95.18  E-value: 9.05e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSF----GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPD---AGHILLDQEEITTRPA- 72
Cdd:PRK09473   10 DALLDVKDLRVTFstpdGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANgriGGSATFNGREILNLPEk 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  73 --NR---RPMGMVFQS--YALFPHMTAEQNVAFGLRL-RRLPPALIRQRCEELLALVGLAE---RARSYPHQLSGGQQQR 141
Cdd:PRK09473   90 elNKlraEQISMIFQDpmTSLNPYMRVGEQLMEVLMLhKGMSKAEAFEESVRMLDAVKMPEarkRMKMYPHEFSGGMRQR 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 142 VALARALAVEPKVLLLDEPLSALDAAVR---VTLREEIRRiqqQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTP 218
Cdd:PRK09473  170 VMIAMALLCRPKLLIADEPTTALDVTVQaqiMTLLNELKR---EFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNA 246

                         250       260
                  ....*....|....*....|....
gi 1424145480 219 EEIYRRPRTVFVAGFVGASTRLSA 242
Cdd:PRK09473  247 RDVFYQPSHPYSIGLLNAVPRLDA 270
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 4-221 9.56e-22

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 97.78  E-value: 9.56e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480    4 LELQELTKSFGKTR--AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN-RRPMGMV 80
Cdd:TIGR01257 1938 LRLNELTKVYSGTSspAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDvHQNMGYC 2017

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   81 FQSYALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:TIGR01257 2018 PQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEP 2097

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480  161 LSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:TIGR01257 2098 TTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHL 2157
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 19-226 1.79e-21

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 92.84  E-value: 1.79e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  19 VERISLGVERGEFLTLLGPSGCGKT-----TVLRLVAGFEQPdAGHILLDQEEITTRPANRRPMGMVFQS--YALFPHMT 91
Cdd:PRK10418   19 VHGVSLTLQRGRVLALVGGSGSGKSltcaaALGILPAGVRQT-AGRVLLDGKPVAPCALRGRKIATIMQNprSAFNPLHT 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  92 AEQNVAFGLRLRRLPPAliRQRCEELLALVGLAERAR---SYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAV 168
Cdd:PRK10418   98 MHTHARETCLALGKPAD--DATLTAALEAVGLENAARvlkLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVA 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 169 RVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYRRPR 226
Cdd:PRK10418  176 QARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPK 233
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 4-210 2.19e-21

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 95.89  E-value: 2.19e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT-TRPANRRPMG--MV 80
Cdd:PRK15439   12 LCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCArLTPAKAHQLGiyLV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAFGLRLRRLPpaliRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:PRK15439   92 PQEPLLFPNLSVKENILFGLPKRQAS----MQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILILDEP 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARG 210
Cdd:PRK15439  168 TASLTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDG 216
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 4-193 2.42e-21

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 95.89  E-value: 2.42e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMV 80
Cdd:TIGR02868 335 LELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDevRRRVSVC 414

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFpHMTAEQNVAFGlrlrrlPPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARALA 149
Cdd:TIGR02868 415 AQDAHLF-DTTVRENLRLA------RPDATDEELWAALERVGLADWLRALPDgldtvlgeggaRLSGGERQRLALARALL 487

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1424145480 150 VEPKVLLLDEPLSALDAAVRVTLREEIRRIQQqlGMTVIYVTHD 193
Cdd:TIGR02868 488 ADAPILLLDEPTEHLDAETADELLEDLLAALS--GRTVVLITHH 529
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 19-192 3.04e-21

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 95.64  E-value: 3.04e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  19 VERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeeitTRPANRRPMGMVFQSYalFPHMTAEQNVAF 98
Cdd:COG4178   379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRI--------ARPAGARVLFLPQRPY--LPLGTLREALLY 448

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  99 GLRLRRLPPAlirqRCEELLALVGLAERA------RSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAvrvTL 172
Cdd:COG4178   449 PATAEAFSDA----ELREALEAVGLGHLAerldeeADWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEE---NE 521

                         170       180
                  ....*....|....*....|.
gi 1424145480 173 REEIRRIQQQL-GMTVIYVTH 192
Cdd:COG4178   522 AALYQLLREELpGTTVISVGH 542
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 4-223 5.82e-21

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 89.89  E-value: 5.82e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFE--QPDAGHILLDQEEITTRPAN---RRPMG 78
Cdd:cd03217     1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDITDLPPEeraRLGIF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPhmtaeqnvafGLRLrrlppalirqrcEELLalvglaeraRSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:cd03217    81 LAFQYPPEIP----------GVKN------------ADFL---------RYVNEGFSGGEKKRNEILQLLLLEPDLAILD 129

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 159 EPLSALDA-AVRVtLREEIRRIQQQlGMTVIYVTHDQEEALAISG-RIAVMARGRLEQLGTPE---EIYR 223
Cdd:cd03217   130 EPDSGLDIdALRL-VAEVINKLREE-GKSVLIITHYQRLLDYIKPdRVHVLYDGRIVKSGDKElalEIEK 197
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
5-221 7.03e-21

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 94.64  E-value: 7.03e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSF-GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMVF 81
Cdd:PRK13657  336 EFDDVSFSYdNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRtvTRASLRRNIAVVF 415

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  82 QSYALFpHMTAEQNVAFG--------LRL---RRLPPALIRQRCEELLALVGlaERARsyphQLSGGQQQRVALARALAV 150
Cdd:PRK13657  416 QDAGLF-NRSIEDNIRVGrpdatdeeMRAaaeRAQAHDFIERKPDGYDTVVG--ERGR----QLSGGERQRLAIARALLK 488

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 151 EPKVLLLDEPLSALDAAVRVTLREEIRRIQQqlGMTVIYVTHdqeeALAI---SGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK13657  489 DPPILILDEATSALDVETEAKVKAALDELMK--GRTTFIIAH----RLSTvrnADRILVFDNGRVVESGSFDEL 556
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 22-211 8.17e-21

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 89.45  E-value: 8.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLdqeeittrpanRRPMGMVFQSYALFPhMTAEQNVAFGLR 101
Cdd:cd03250    24 INLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSV-----------PGSIAYVSQEPWIQN-GTIRENILFGKP 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 102 LRRlppalirQRCEELL---AL--------------VGlaERARSyphqLSGGQQQRVALARALAVEPKVLLLDEPLSAL 164
Cdd:cd03250    92 FDE-------ERYEKVIkacALepdleilpdgdlteIG--EKGIN----LSGGQKQRISLARAVYSDADIYLLDDPLSAV 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1424145480 165 DAAVRVTLREEIrrIQQQL--GMTVIYVTHdQEEALAISGRIAVMARGR 211
Cdd:cd03250   159 DAHVGRHIFENC--ILGLLlnNKTRILVTH-QLQLLPHADQIVVLDNGR 204
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 22-221 1.10e-20

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 93.58  E-value: 1.10e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-PANRRPMGMVF-----QSYALFPHMTAEQN 95
Cdd:PRK15439  282 ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALsTAQRLARGLVYlpedrQSSGLYLDAPLAWN 361

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  96 VAfGLRLRRLP----PALIRQRCEELLALVGLA-ERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRV 170
Cdd:PRK15439  362 VC-ALTHNRRGfwikPARENAVLERYRRALNIKfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARN 440

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 171 TLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK15439  441 DIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGEISGALTGAAI 490
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 29-220 1.26e-20

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 93.96  E-value: 1.26e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  29 GEFLTLLGPSGCGKTTVLRLVAGFEQPD---AGHILLDQEEITtRPANRRPMGMVFQSYALFPHMTAEQNVAFGLRLR-- 103
Cdd:TIGR00955  51 GELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPID-AKEMRAISAYVQQDDLFIPTLTVREHLMFQAHLRmp 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 104 -RLPPALIRQRCEELLALVGLAERARS---YPHQ---LSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEI 176
Cdd:TIGR00955 130 rRVTKKEKRERVDEVLQALGLRKCANTrigVPGRvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVL 209

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1424145480 177 RRIQQQlGMTVIYVTHD-QEEALAISGRIAVMARGRLEQLGTPEE 220
Cdd:TIGR00955 210 KGLAQK-GKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSPDQ 253
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
20-212 1.92e-20

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 93.05  E-value: 1.92e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  20 ERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-PANRRPMGMVF-----QSYALFPHMTAE 93
Cdd:PRK11288  270 EPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRsPRDAIRAGIMLcpedrKAEGIIPVHSVA 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  94 QNVAFGLRLRRLPPA-LIRQRCEELLA---LVGLAERARSyPHQ----LSGGQQQRVALARALAVEPKVLLLDEPLSALD 165
Cdd:PRK11288  350 DNINISARRHHLRAGcLINNRWEAENAdrfIRSLNIKTPS-REQlimnLSGGNQQKAILGRWLSEDMKVILLDEPTRGID 428

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1424145480 166 aavrVTLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:PRK11288  429 ----VGAKHEIYNVIYELaaqGVAVLFVSSDLPEVLGVADRIVVMREGRI 474
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 4-219 1.96e-20

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 89.36  E-value: 1.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFE--QPDAGHILLDQEEITTRPAN---RRPMG 78
Cdd:COG0396     1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPkyEVTSGSILLDGEDILELSPDeraRAGIF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQ--------SYALFPHmTAEQNVafglRLRRLPPALIRQRCEELLALVGLAERA--RSYPHQLSGGQQQRVALARAL 148
Cdd:COG0396    81 LAFQypveipgvSVSNFLR-TALNAR----RGEELSAREFLKLLKEKMKELGLDEDFldRYVNEGFSGGEKKRNEILQML 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 149 AVEPKVLLLDEPLSALDA-AVRVtLREEIRRIQQQlGMTVIYVTHDQE--EALAISgRIAVMARGRLEQLGTPE 219
Cdd:COG0396   156 LLEPKLAILDETDSGLDIdALRI-VAEGVNKLRSP-DRGILIITHYQRilDYIKPD-FVHVLVDGRIVKSGGKE 226
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 4-221 2.77e-20

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 92.88  E-value: 2.77e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTR-AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMV 80
Cdd:TIGR01193 474 IVINDVSYSYGYGSnILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKdiDRHTLRQFINYL 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPH-------MTAEQNVAFGLRLRRLPPALIRQRCEELLalVGLAERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:TIGR01193 554 PQEPYIFSGsilenllLGAKENVSQDEIWAACEIAEIKDDIENMP--LGYQTELSEEGSSISGGQKQRIALARALLTDSK 631

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQlgmTVIYVTHDQEEAlAISGRIAVMARGRLEQLGTPEEI 221
Cdd:TIGR01193 632 VLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVA-KQSDKIIVLDHGKIIEQGSHDEL 695
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 18-220 5.75e-20

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 91.81  E-value: 5.75e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMVFQSYALFPHmTAEQN 95
Cdd:PRK11160  355 VLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIAdySEAALRQAISVVSQRVHLFSA-TLRDN 433

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  96 VAFGLrlrrlpPALIRQRCEELLALVGLAERARSYP----------HQLSGGQQQRVALARALAVEPKVLLLDEPLSALD 165
Cdd:PRK11160  434 LLLAA------PNASDEALIEVLQQVGLEKLLEDDKglnawlgeggRQLSGGEQRRLGIARALLHDAPLLLLDEPTEGLD 507

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 166 AavrvtlREEiRRIQQQL-----GMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEE 220
Cdd:PRK11160  508 A------ETE-RQILELLaehaqNKTVLMITH-RLTGLEQFDRICVMDNGQIIEQGTHQE 559
PLN03211 PLN03211
ABC transporter G-25; Provisional
 29-263 5.84e-20

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 91.86  E-value: 5.84e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  29 GEFLTLLGPSGCGKTTVLRLVAGFEQPD--AGHILLDQEEITtRPANRRpMGMVFQSYALFPHMTAEQNVAFgLRLRRLP 106
Cdd:PLN03211   94 GEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPT-KQILKR-TGFVTQDDILYPHLTVRETLVF-CSLLRLP 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 107 PALIRQR----CEELLALVGLAE-----RARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIR 177
Cdd:PLN03211  171 KSLTKQEkilvAESVISELGLTKcentiIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLG 250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 178 RIQQQlGMTVIYVTHD-QEEALAISGRIAVMARGRLEQLGTPEEiyrrprTVFVAGFVGASTRLSAR----LERAVEGRC 252
Cdd:PLN03211  251 SLAQK-GKTIVTSMHQpSSRVYQMFDSVLVLSEGRCLFFGKGSD------AMAYFESVGFSPSFPMNpadfLLDLANGVC 323

                         250
                  ....*....|.
gi 1424145480 253 RLDGILLRVPP 263
Cdd:PLN03211  324 QTDGVSEREKP 334
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
5-223 1.09e-19

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 90.61  E-value: 1.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELT-KSFGKtraVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP---ANRRPMGMV 80
Cdd:PRK09700  267 EVRNVTsRDRKK---VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSpldAVKKGMAYI 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSY---ALFPHMTAEQNVAFG--LRLRRLPPA--LIRQRCEEllalvGLAERARSYPH-----------QLSGGQQQRV 142
Cdd:PRK09700  344 TESRrdnGFFPNFSIAQNMAISrsLKDGGYKGAmgLFHEVDEQ-----RTAENQRELLAlkchsvnqnitELSGGNQQKV 418

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 143 ALARALAVEPKVLLLDEPLSALDaavrVTLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRLEQL---- 215
Cdd:PRK09700  419 LISKWLCCCPEVIIFDEPTRGID----VGAKAEIYKVMRQLaddGKVILMVSSELPEIITVCDRIAVFCEGRLTQIltnr 494

                         250
                  ....*....|
gi 1424145480 216 --GTPEEIYR 223
Cdd:PRK09700  495 ddMSEEEIMA 504
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 4-193 2.91e-19

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 89.35  E-value: 2.91e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHI---------LLDQEEITtrpanr 74
Cdd:COG0488   316 LELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVklgetvkigYFDQHQEE------ 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 rpmgmvfqsyaLFPHMTAEQNvafglrLRRLPPALIRQRCEELLALVGLA-ERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:COG0488   390 -----------LDPDKTVLDE------LRDGAPGGTEQEVRGYLGRFLFSgDDAFKPVGVLSGGEKARLALAKLLLSPPN 452

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1424145480 154 VLLLDEPLSALDAavrvtlrEEIRRIQQQL----GmTVIYVTHD 193
Cdd:COG0488   453 VLLLDEPTNHLDI-------ETLEALEEALddfpG-TVLLVSHD 488
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 22-221 4.88e-19

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 85.66  E-value: 4.88e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFeQPDAGHILLDQEEITTRP----ANRR---------PMGM-VFQSYALF 87
Cdd:COG4138    15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGL-LPGQGEILLNGRPLSDWSaaelARHRaylsqqqspPFAMpVFQYLALH 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  88 -PHMTAEQNVAfglrlrrlppALIRQRCEELlalvGLAERARSYPHQLSGGQQQRVALARAL-----AVEP--KVLLLDE 159
Cdd:COG4138    94 qPAGASSEAVE----------QLLAQLAEAL----GLEDKLSRPLTQLSGGEWQRVRLAAVLlqvwpTINPegQLLLLDE 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 160 PLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:COG4138   160 PMNSLDVAQQAALDRLLRELCQQ-GITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEV 220
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 2-210 1.08e-18

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 87.75  E-value: 1.08e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   2 AFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT---TRPANRRPMG 78
Cdd:PRK10762    3 ALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTfngPKSSQEAGIG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPHMTAEQNVAFGL----RLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKV 154
Cdd:PRK10762   83 IIHQELNLIPQLTIAENIFLGRefvnRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKV 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 155 LLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARG 210
Cdd:PRK10762  163 IIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFRDG 217
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
1-225 1.43e-18

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 86.01  E-value: 1.43e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSF----GKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQpDAGHILLDQ------EEITTR 70
Cdd:PRK15093    1 MPLLDIRNLTIEFktsdGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTK-DNWRVTADRmrfddiDLLRLS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  71 PANRRP-----MGMVFQSyalfPHMTAEQNVAFGLRLRRLPPALI------------RQRCEELLALVGLAERA---RSY 130
Cdd:PRK15093   80 PRERRKlvghnVSMIFQE----PQSCLDPSERVGRQLMQNIPGWTykgrwwqrfgwrKRRAIELLHRVGIKDHKdamRSF 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 131 PHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARG 210
Cdd:PRK15093  156 PYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCG 235

                         250
                  ....*....|....*
gi 1424145480 211 RLEQLGTPEEIYRRP 225
Cdd:PRK15093  236 QTVETAPSKELVTTP 250
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 4-215 2.12e-18

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 86.95  E-value: 2.12e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTR-AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMV 80
Cdd:PRK10522  323 LELRNVTFAYQDNGfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTaeQPEDYRKLFSAV 402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSYALFPHMTAEQNVAfglrlrrLPPALIrqrcEELLALVGLAERARSYPH-----QLSGGQQQRVALARALAVEPKVL 155
Cdd:PRK10522  403 FTDFHLFDQLLGPEGKP-------ANPALV----EKWLERLKMAHKLELEDGrisnlKLSKGQKKRLALLLALAEERDIL 471

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 156 LLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDqEEALAISGRIAVMARGRLEQL 215
Cdd:PRK10522  472 LLDEWAADQDPHFRREFYQVLLPLLQEMGKTIFAISHD-DHYFIHADRLLEMRNGQLSEL 530
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 22-221 2.59e-18

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 86.82  E-value: 2.59e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFeQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFpHMTAEQNVAFG 99
Cdd:PRK11174  369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKINGIELRELDPEswRKHLSWVGQNPQLP-HGTLRDNVLLG 446

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 100 lrlrrlPPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARALAVEPKVLLLDEPLSALDA-- 166
Cdd:PRK11174  447 ------NPDASDEQLQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLLLDEPTASLDAhs 520

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 167 --AVRVTLREEIRriqqqlGMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK11174  521 eqLVMQALNAASR------RQTTLMVTH-QLEDLAQWDQIWVMQDGQIVQQGDYAEL 570
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 19-192 2.60e-18

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 81.43  E-value: 2.60e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  19 VERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeeittrpanrrpmgmvfqsyalfpHMTAEQNVAF 98
Cdd:cd03223    17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRI----------------------------GMPEGEDLLF 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  99 glrlrrLP--PALIRQRCEELLAlvglaerarsYP--HQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVrvtlRE 174
Cdd:cd03223    69 ------LPqrPYLPLGTLREQLI----------YPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEES----ED 128

                         170
                  ....*....|....*...
gi 1424145480 175 EIRRIQQQLGMTVIYVTH 192
Cdd:cd03223   129 RLYQLLKELGITVISVGH 146
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 22-209 2.91e-18

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 82.90  E-value: 2.91e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFPHMTAEqNVAFG 99
Cdd:cd03248    33 VSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKylHSKVSLVGQEPVLFARSLQD-NIAYG 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 100 LR---LRRLPPALIRQRCEELLALV--GLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAavrvtlrE 174
Cdd:cd03248   112 LQscsFECVKEAAQKAHAHSFISELasGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDA-------E 184

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1424145480 175 EIRRIQQQLgmtviYVTHDQEEALAISGRIAVMAR 209
Cdd:cd03248   185 SEQQVQQAL-----YDWPERRTVLVIAHRLSTVER 214
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
4-221 5.98e-18

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 84.40  E-value: 5.98e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVlRLVAGFEQPDAGHillDQEEITTRPANRRPMGMVFQS 83
Cdd:NF000106   14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGR---RPWRF*TWCANRRALRRTIG* 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 Y-----ALFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:NF000106   90 Hrpvr*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLD 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:NF000106  170 EPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 4-212 6.18e-18

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 85.44  E-value: 6.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSfgktrAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTR-PANRRPMGMVFQ 82
Cdd:PRK10762  258 LKVDNLSGP-----GVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRsPQDGLANGIVYI 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SY-----ALFPHMTAEQNVA---------FGLRLRRlppALIRQRCEELLALVGLAERARSYP-HQLSGGQQQRVALARA 147
Cdd:PRK10762  333 SEdrkrdGLVLGMSVKENMSltalryfsrAGGSLKH---ADEQQAVSDFIRLFNIKTPSMEQAiGLLSGGNQQKVAIARG 409

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 148 LAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:PRK10762  410 LMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLGMSDRILVMHEGRI 473
GguA NF040905
sugar ABC transporter ATP-binding protein;
4-211 9.75e-18

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 84.84  E-value: 9.75e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAG------FEqpdaGHILLDQEEI---TTRPANR 74
Cdd:NF040905    2 LEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyphgsYE----GEILFDGEVCrfkDIRDSEA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 RPMGMVFQSYALFPHMTAEQNVAFG-LRLRRlppALI-----RQRCEELLALVGLAERARSYPHQLSGGQQQRVALARAL 148
Cdd:NF040905   78 LGIVIIHQELALIPYLSIAENIFLGnERAKR---GVIdwnetNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKAL 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 149 AVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:NF040905  155 SKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGR 216
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 22-220 7.14e-17

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 82.56  E-value: 7.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMVFQSYALFpHMTAEQNVAFG 99
Cdd:COG5265   377 VSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRdvTQASLRAAIGIVPQDTVLF-NDTIAYNIAYG 455

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 100 ------------LRLRRLPpALIRQRCEELLALVGlaERARsyphQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAA 167
Cdd:COG5265   456 rpdaseeeveaaARAAQIH-DFIESLPDGYDTRVG--ERGL----KLSGGEKQRVAIARTLLKNPPILIFDEATSALDSR 528

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 168 VRVTLREEIRRIQQqlGMTVIYVTH--------DQeealaisgrIAVMARGRLEQLGTPEE 220
Cdd:COG5265   529 TERAIQAALREVAR--GRTTLVIAHrlstivdaDE---------ILVLEAGRIVERGTHAE 578
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 22-221 2.90e-16

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 77.67  E-value: 2.90e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFeQPDAGHILLDQEEITTRPAN-------------RRPMGM-VFQSYALf 87
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAelarhraylsqqqTPPFAMpVFQYLTL- 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  88 pHMTAEQNVafglrlrrlppALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARA-LAVEP------KVLLLDEP 160
Cdd:PRK03695   93 -HQPDKTRT-----------EAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVvLQVWPdinpagQLLLLDEP 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK03695  161 MNSLDVAQQAALDRLLSELCQQ-GIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEV 220
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 23-206 4.12e-16

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 77.45  E-value: 4.12e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  23 SLGVERGEF-----LTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAnrrpmgmvfqsyalfpHMTAEQNVa 97
Cdd:cd03237    14 TLEVEGGSIsesevIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSYKPQ----------------YIKADYEG- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  98 fglRLRRLPPALIRQRCEEL---------LALVGLAERARSyphQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAV 168
Cdd:cd03237    77 ---TVRDLLSSITKDFYTHPyfkteiakpLQIEQILDREVP---ELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQ 150

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1424145480 169 RVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAV 206
Cdd:cd03237   151 RLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIV 188
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
26-165 4.21e-16

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 76.43  E-value: 4.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  26 VERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeEITTRPANR--RPMGMVFQSY--ALFPHMTAEQNVAF--- 98
Cdd:PRK13543   34 VDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQI-----QIDGKTATRgdRSRFMAYLGHlpGLKADLSTLENLHFlcg 108

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480  99 --GLRLRRLPpalirqrcEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALD 165
Cdd:PRK13543  109 lhGRRAKQMP--------GSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLD 169
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 5-195 5.10e-16

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 76.54  E-value: 5.10e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKT-RAVER-----ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFE--QPDAGHILLDQEEITtrpanrrp 76
Cdd:COG2401    26 RVAIVLEAFGVElRVVERyvlrdLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVPDNQFG-------- 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  77 mgmvfQSYALFPHMTAEQNVAFGLrlrrlppalirqrceELLALVGLAE----RARsyPHQLSGGQQQRVALARALAVEP 152
Cdd:COG2401    98 -----REASLIDAIGRKGDFKDAV---------------ELLNAVGLSDavlwLRR--FKELSTGQKFRFRLALLLAERP 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1424145480 153 KVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQE 195
Cdd:COG2401   156 KLLVIDEFCSHLDRQTAKRVARNLQKLARRAGITLVVATHHYD 198
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 4-218 1.02e-15

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 75.14  E-value: 1.02e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGK--TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRP--ANRRPMGM 79
Cdd:cd03369     7 IEVENLSVRYAPdlPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPleDLRSSLTI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHmTAEQNV-AFGlrlrrlppaliRQRCEELLALVGLAERARSyphqLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:cd03369    87 IPQDPTLFSG-TIRSNLdPFD-----------EYSDEEIYGALRVSEGGLN----LSQGQRQLLCLARALLKRPRVLVLD 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 159 EPLSAL----DAAVRVTLREEIRriqqqlGMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTP 218
Cdd:cd03369   151 EATASIdyatDALIQKTIREEFT------NSTILTIAH-RLRTIIDYDKILVMDAGEVKEYDHP 207
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
4-193 1.88e-15

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 77.93  E-value: 1.88e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKtraverISLGVE-----RGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDqEEITTRPanrrpmg 78
Cdd:PRK13409  341 VEYPDLTKKLGD------FSLEVEggeiyEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE-LKISYKP------- 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 mvfQsyalfpHMTAEQNVAFGLRLRRLPPAL----IRqrcEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKV 154
Cdd:PRK13409  407 ---Q------YIKPDYDGTVEDLLRSITDDLgssyYK---SEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADL 474

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1424145480 155 LLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHD 193
Cdd:PRK13409  475 YLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHD 513
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
5-224 2.33e-15

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 77.86  E-value: 2.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIttrpANRRPMGMVFQSY 84
Cdd:NF033858    3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDM----ADARHRRAVCPRI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  85 A---------LFPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVL 155
Cdd:NF033858   79 AympqglgknLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLL 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 156 LLDEPLSALDAAVRV---TLREEIRRiqQQLGMTVIYVTHDQEEAlaisGR---IAVMARGRLEQLGTPEEIYRR 224
Cdd:NF033858  159 ILDEPTTGVDPLSRRqfwELIDRIRA--ERPGMSVLVATAYMEEA----ERfdwLVAMDAGRVLATGTPAELLAR 227
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 4-192 3.24e-15

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 73.83  E-value: 3.24e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT-RPANRRPMGMVFQ 82
Cdd:PRK13540    2 LDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKdLCTYQKQLCFVGH 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  83 SYALFPHMTAEQNVAFGLRLRRLPPALirqrcEELLALVGLaERARSYP-HQLSGGQQQRVALARALAVEPKVLLLDEPL 161
Cdd:PRK13540   82 RSGINPYLTLRENCLYDIHFSPGAVGI-----TELCRLFSL-EHLIDYPcGLLSSGQKRQVALLRLWMSKAKLWLLDEPL 155

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1424145480 162 SALDAAVRVTLREEIRRIQQQlGMTVIYVTH 192
Cdd:PRK13540  156 VALDELSLLTIITKIQEHRAK-GGAVLLTSH 185
hmuV PRK13547
heme ABC transporter ATP-binding protein;
22-223 4.96e-15

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 74.48  E-value: 4.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAG-FEQPDA-------GHILLDQEEITTRPANRrpmgmVFQSYALFPHmTAE 93
Cdd:PRK13547   20 LSLRIEPGRVTALLGRNGAGKSTLLKALAGdLTGGGAprgarvtGDVTLNGEPLAAIDAPR-----LARLRAVLPQ-AAQ 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  94 QNVAFGLR----LRRLPPA------LIRQR--CEELLALVGLAERARSYPHQLSGGQQQRVALARALA---------VEP 152
Cdd:PRK13547   94 PAFAFSAReivlLGRYPHArragalTHRDGeiAWQALALAGATALVGRDVTTLSGGELARVQFARVLAqlwpphdaaQPP 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 153 KVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEIYR 223
Cdd:PRK13547  174 RYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVLT 244
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 17-212 8.71e-15

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 75.74  E-value: 8.71e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  17 RAVERISLGVERGEFLTLLGPSGCGKT-TVLRLVAGFEQPDAGHILLDQEEITTR---PANRRPMGMVFQS---YALFPH 89
Cdd:PRK13549  276 KRVDDVSFSLRRGEILGIAGLVGAGRTeLVQCLFGAYPGRWEGEIFIDGKPVKIRnpqQAIAQGIAMVPEDrkrDGIVPV 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  90 MTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPH------QLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:PRK13549  356 MGVGKNITLAALDRFTGGSRIDDAAELKTILESIQRLKVKTASpelaiaRLSGGNQQKAVLAKCLLLNPKILILDEPTRG 435

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 164 LDaavrVTLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:PRK13549  436 ID----VGAKYEIYKLINQLvqqGVAIIVISSELPEVLGLSDRVLVMHEGKL 483
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 15-213 1.16e-14

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 75.25  E-value: 1.16e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  15 KTRAVERISLGVERGEFLTLLGPSGCGKT-TVLRLVAGFEQPDAGHILLDQEEITTR-------------PANRRPMGMV 80
Cdd:TIGR02633 272 HRKRVDDVSFSLRRGEILGVAGLVGAGRTeLVQALFGAYPGKFEGNVFINGKPVDIRnpaqairagiamvPEDRKRHGIV 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 fqsyalfPHMTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPH------QLSGGQQQRVALARALAVEPKV 154
Cdd:TIGR02633 352 -------PILGVGKNITLSVLKSFCFKMRIDAAAELQIIGSAIQRLKVKTASpflpigRLSGGNQQKAVLAKMLLTNPRV 424

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 155 LLLDEPLSALDaavrVTLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRLE 213
Cdd:TIGR02633 425 LILDEPTRGVD----VGAKYEIYKLINQLaqeGVAIIVVSSELAEVLGLSDRVLVIGEGKLK 482
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 22-218 1.62e-14

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 72.14  E-value: 1.62e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTV----LRLVagfeQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFPHmTAEQN 95
Cdd:cd03244    23 ISFSIKPGEKVGIVGRTGSGKSSLllalFRLV----ELSSGSILIDGVDISKIGLHdlRSRISIIPQDPVLFSG-TIRSN 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  96 vafglrlrrLPPaliRQRC--EEL---LALVGLAERARSYPHQL-----------SGGQQQRVALARALAVEPKVLLLDE 159
Cdd:cd03244    98 ---------LDP---FGEYsdEELwqaLERVGLKEFVESLPGGLdtvveeggenlSVGQRQLLCLARALLRKSKILVLDE 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 160 PLSALD----AAVRVTLREEIRriqqqlGMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTP 218
Cdd:cd03244   166 ATASVDpetdALIQKTIREAFK------DCTVLTIAH-RLDTIIDSDRILVLDKGRVVEFDSP 221
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
16-223 4.60e-14

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 73.90  E-value: 4.60e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  16 TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMVFQSYALFpHMTAE 93
Cdd:PRK11176  356 VPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRdyTLASLRNQVALVSQNVHLF-NDTIA 434

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  94 QNVAFGLRLR----------RLPPAL--IRQRCEELLALVGlaERARSyphqLSGGQQQRVALARALAVEPKVLLLDEPL 161
Cdd:PRK11176  435 NNIAYARTEQysreqieeaaRMAYAMdfINKMDNGLDTVIG--ENGVL----LSGGQRQRIAIARALLRDSPILILDEAT 508

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 162 SALDAavrvtlrEEIRRIQQQL-----GMTVIYVTH------DQEEALAIS-GRIavMARGR----LEQLGTPEEIYR 223
Cdd:PRK11176  509 SALDT-------ESERAIQAALdelqkNRTSLVIAHrlstieKADEILVVEdGEI--VERGThaelLAQNGVYAQLHK 577
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
4-188 6.29e-14

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 73.21  E-value: 6.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAV-ERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITT--RPANRRPMGMV 80
Cdd:PRK10790  341 IDIDNVSFAYRDDNLVlQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSlsHSVLRQGVAMV 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  81 FQSyalfPHMTAEQ---NVAFGLRLRRlppalirQRCEELLALVGLAERARSYP-----------HQLSGGQQQRVALAR 146
Cdd:PRK10790  421 QQD----PVVLADTflaNVTLGRDISE-------EQVWQALETVQLAELARSLPdglytplgeqgNNLSVGQKQLLALAR 489

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1424145480 147 ALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVI 188
Cdd:PRK10790  490 VLVQTPQILILDEATANIDSGTEQAIQQALAAVREHTTLVVI 531
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 4-173 1.19e-13

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 72.28  E-value: 1.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQeeiTTRpanrrpMGMVFQS 83
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGE---TVK------LAYVDQS 393

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 Y-ALFPHMTAEQNVAFGLRLRRLPPALIRQRceellALVGL----AERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:TIGR03719 394 RdALDPNKTVWEEISGGLDIIKLGKREIPSR-----AYVGRfnfkGSDQQKKVGQLSGGERNRVHLAKTLKSGGNVLLLD 468

                         170
                  ....*....|....*
gi 1424145480 159 EPLSALDAAvrvTLR 173
Cdd:TIGR03719 469 EPTNDLDVE---TLR 480
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 8-193 1.34e-13

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 72.12  E-value: 1.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   8 ELTKSFGKtraverISLGVE-----RGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQE------------EITTR 70
Cdd:COG1245   346 DLTKSYGG------FSLEVEggeirEGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLKisykpqyispdyDGTVE 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  71 PANRRPMGMVFQSYALfphmtaEQNVAFGLRLRRLppaLIRQRCEellalvglaerarsyphqLSGGQQQRVALARALAV 150
Cdd:COG1245   420 EFLRSANTDDFGSSYY------KTEIIKPLGLEKL---LDKNVKD------------------LSGGELQRVAIAACLSR 472

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1424145480 151 EPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTHD 193
Cdd:COG1245   473 DADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHD 515
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 22-192 1.45e-13

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 69.28  E-value: 1.45e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIL------LDQEEITTRPANRRPMGMVFQSYALFpHMTAEQN 95
Cdd:cd03290    20 INIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHwsnkneSEPSFEATRSRNRYSVAYAAQKPWLL-NATVEEN 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  96 VAFGlrlrrlpPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARALAVEPKVLLLDEPLSAL 164
Cdd:cd03290    99 ITFG-------SPFNKQRYKAVTDACSLQPDIDLLPFgdqteigergiNLSGGQRQRICVARALYQNTNIVFLDDPFSAL 171

                         170       180
                  ....*....|....*....|....*....
gi 1424145480 165 DAAVRVTLREE-IRRIQQQLGMTVIYVTH 192
Cdd:cd03290   172 DIHLSDHLMQEgILKFLQDDKRTLVLVTH 200
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
18-225 2.02e-13

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 71.67  E-value: 2.02e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFPHMTAeQN 95
Cdd:PRK10789  330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDswRSRLAVVSQTPFLFSDTVA-NN 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  96 VAFGlrlrrlPPALIRQRCEELLALVGLAERARSYPH-----------QLSGGQQQRVALARALAVEPKVLLLDEPLSAL 164
Cdd:PRK10789  409 IALG------RPDATQQEIEHVARLASVHDDILRLPQgydtevgergvMLSGGQKQRISIARALLLNAEILILDDALSAV 482

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424145480 165 DAAVRVTLREEIRRIQQqlGMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PRK10789  483 DGRTEHQILHNLRQWGE--GRTVIISAH-RLSALTEASEILVMQHGHIAQRGNHDQLAQQS 540
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 6-193 2.39e-13

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 71.50  E-value: 2.39e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   6 LQELTKSFGKTRAV-ERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHilldqeeitTRPANRRPMGMVFQSY 84
Cdd:TIGR03719   7 MNRVSKVVPPKKEIlKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGE---------ARPQPGIKVGYLPQEP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  85 ALFPHMTAEQNVAFGLR-----LRRL---------PPA-----LIRQ-RCEELLALVGL------AERA----RSYP--- 131
Cdd:TIGR03719  78 QLDPTKTVRENVEEGVAeikdaLDRFneisakyaePDAdfdklAAEQaELQEIIDAADAwdldsqLEIAmdalRCPPwda 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 132 --HQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAavrvtlrEEIRRIQQQL----GmTVIYVTHD 193
Cdd:TIGR03719 158 dvTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDA-------ESVAWLERHLqeypG-TVVAVTHD 217
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 22-224 6.86e-13

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 70.74  E-value: 6.86e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLdqeeittrpanRRPMGMVFQSyALFPHMTAEQNVAFGLR 101
Cdd:TIGR00957  657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHM-----------KGSVAYVPQQ-AWIQNDSLRENILFGKA 724

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  102 LRRLPPALIRQRCEELLALVGLAERARSYPHQ----LSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIR 177
Cdd:TIGR00957  725 LNEKYYQQVLEACALLPDLEILPSGDRTEIGEkgvnLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFEHVI 804

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1424145480  178 RIQQQL-GMTVIYVTHDQeEALAISGRIAVMARGRLEQLGTPEEIYRR 224
Cdd:TIGR00957  805 GPEGVLkNKTRILVTHGI-SYLPQVDVIIVMSGGKISEMGSYQELLQR 851
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
18-193 9.16e-13

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 67.99  E-value: 9.16e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQeeITTRPANRRPM-GMVFQSYAL---FPhMTAE 93
Cdd:PRK15056   22 ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILG--QPTRQALQKNLvAYVPQSEEVdwsFP-VLVE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  94 QNVAFG----LRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVR 169
Cdd:PRK15056   99 DVVMMGryghMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTE 178

                         170       180
                  ....*....|....*....|....
gi 1424145480 170 VTLREEIRRIQQQlGMTVIYVTHD 193
Cdd:PRK15056  179 ARIISLLRELRDE-GKTMLVSTHN 201
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 1-212 1.03e-12

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 69.59  E-value: 1.03e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   1 MAFLELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGfEQP-DAGHILLDQEEITTR-----PanR 74
Cdd:PRK11147    1 MSLISIHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNG-EVLlDDGRIIYEQDLIVARlqqdpP--R 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 RPMGMVF--------------QSYALFPHMTA----EQNVAfglRLRRLPPALIRQ-------RCEELLALVGL-AERAR 128
Cdd:PRK11147   78 NVEGTVYdfvaegieeqaeylKRYHDISHLVEtdpsEKNLN---ELAKLQEQLDHHnlwqlenRINEVLAQLGLdPDAAL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 129 SyphQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAavrvtlrEEIRRIQQQL---GMTVIYVTHDQEEALAISGRIA 205
Cdd:PRK11147  155 S---SLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDI-------ETIEWLEGFLktfQGSIIFISHDRSFIRNMATRIV 224


                  ....*..
gi 1424145480 206 VMARGRL 212
Cdd:PRK11147  225 DLDRGKL 231
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 9-211 2.11e-12

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 68.22  E-value: 2.11e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   9 LTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEI---TTRPANRRPMGMVFQSYa 85
Cdd:PRK10982    4 ISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIdfkSSKEALENGISMVHQEL- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  86 lfpHMTAEQNVAFGLRLRRLPP-------ALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLD 158
Cdd:PRK10982   83 ---NLVLQRSVMDNMWLGRYPTkgmfvdqDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMD 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 159 EPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQEEALAISGRIAVMARGR 211
Cdd:PRK10982  160 EPTSSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQ 211
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 22-211 3.49e-12

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 64.98  E-value: 3.49e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAG----FEQPDaGHIL---LDQEEITTRPanRRPMGMVFQSYALFPHMTAEQ 94
Cdd:cd03233    26 FSGVVKPGEMVLVLGRPGSGCSTLLKALANrtegNVSVE-GDIHyngIPYKEFAEKY--PGEIIYVSEEDVHFPTLTVRE 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  95 NVAFGLRLRrlppalirqrceellalvglaerARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLRE 174
Cdd:cd03233   103 TLDFALRCK-----------------------GNEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTALEILK 159

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1424145480 175 EIRRIQQQLGMTVIyVTHDQ--EEALAISGRIAVMARGR 211
Cdd:cd03233   160 CIRTMADVLKTTTF-VSLYQasDEIYDLFDKVLVLYEGR 197
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 22-193 9.19e-12

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 66.36  E-value: 9.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEIT--TRPANRRPMGMVFQSYALFPHMTAEQNVAFg 99
Cdd:COG4615   351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTadNREAYRQLFSAVFSDFHLFDRLLGLDGEAD- 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 100 lrlrrlpPALIRqrceELLALVGLAERARSYPH-----QLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVR-VTLR 173
Cdd:COG4615   430 -------PARAR----ELLERLELDHKVSVEDGrfsttDLSQGQRKRLALLVALLEDRPILVFDEWAADQDPEFRrVFYT 498

                         170       180
                  ....*....|....*....|
gi 1424145480 174 EEIRRIQQQlGMTVIYVTHD 193
Cdd:COG4615   499 ELLPELKAR-GKTVIAISHD 517
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 56-192 1.74e-11

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 66.21  E-value: 1.74e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   56 DAGHILLDQEEITTRPAN--RRPMGMVFQSYALFpHMTAEQNVAFGLRlrrlppALIRQRCEELLALVGLAERARSYPHQ 133
Cdd:PTZ00265  1275 NSGKILLDGVDICDYNLKdlRNLFSIVSQEPMLF-NMSIYENIKFGKE------DATREDVKRACKFAAIDEFIESLPNK 1347

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  134 -----------LSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTH 192
Cdd:PTZ00265  1348 ydtnvgpygksLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAH 1417
TOBE_2 pfam08402
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the ...
 275-364 3.44e-11

TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the C-terminal strand of each domain is supplied by the partner. Probably involved in the recognition of small ligands such as molybdenum and sulphate. Found in ABC transporters immediately after the ATPase domain. In this family a strong RPE motif is found at the presumed N-terminus of the domain.


Pssm-ID: 462465 [Multi-domain]  Cd Length: 73  Bit Score: 58.79  E-value: 3.44e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 275 LVVRPELVTLCqlneasgaaadgggqrqGQENVLLGTVELRTFLGAVTRFRVRAAGGQLFTVDLPGLQAGTLVPGQRVRL 354
Cdd:pfam08402   1 LAIRPEKIRLA-----------------AAANGLSGTVTDVEYLGDHTRYHVELAGGEELVVRVPNAHARPPAPGDRVGL 63

                          90
                  ....*....|
gi 1424145480 355 SFPPEACLVL 364
Cdd:pfam08402  64 GWDPEDAHVL 73
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 4-220 4.25e-11

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 64.53  E-value: 4.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeeittRPANRRPMGMVFQS 83
Cdd:PRK15064  320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV---------KWSENANIGYYAQD 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 YA--------LFPHMTA-------EQNVafglR--LRRLppalirqrceellaLVGlAERARSYPHQLSGGQQQRVALAR 146
Cdd:PRK15064  391 HAydfendltLFDWMSQwrqegddEQAV----RgtLGRL--------------LFS-QDDIKKSVKVLSGGEKGRMLFGK 451

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 147 ALAVEPKVLLLDEPLSALDAavrvtlrEEIRRIQQQLGM---TVIYVTHDQEEALAISGRI-AVMARGRLEQLGTPEE 220
Cdd:PRK15064  452 LMMQKPNVLVMDEPTNHMDM-------ESIESLNMALEKyegTLIFVSHDREFVSSLATRIiEITPDGVVDFSGTYEE 522
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 4-212 4.54e-11

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 64.37  E-value: 4.54e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSfgKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN---------- 73
Cdd:PRK10982  251 LEVRNLTSL--RQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANeainhgfalv 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  74 ---RRPMGMV------FQSyaLFPHMTAEQNvAFGLrlrrlppaLIRQRCEELLALVGLAERARSYPHQ-----LSGGQQ 139
Cdd:PRK10982  329 teeRRSTGIYayldigFNS--LISNIRNYKN-KVGL--------LDNSRMKSDTQWVIDSMRVKTPGHRtqigsLSGGNQ 397

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480 140 QRVALARALAVEPKVLLLDEPLSALDaavrVTLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARGRL 212
Cdd:PRK10982  398 QKVIIGRWLLTQPEILMLDEPTRGID----VGAKFEIYQLIAELakkDKGIIIISSEMPELLGITDRILVMSNGLV 469
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 112-221 1.93e-10

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 62.34  E-value: 1.93e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 112 QRCEELLALVG---LAERARSYphqLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVI 188
Cdd:PRK10938  114 ARCEQLAQQFGitaLLDRRFKY---LSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLHQS-GITLV 189

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1424145480 189 YVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK10938  190 LVLNRFDEIPDFVQFAGVLADCTLAETGEREEI 222
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 19-192 1.94e-10

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 62.46  E-value: 1.94e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  19 VERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFeQPDAGHILldqeeitTRPAN-------RRP-MGM-VFQSYALFPh 89
Cdd:TIGR00954 468 IESLSFEVPSGNNLLICGPNGCGKSSLFRILGEL-WPVYGGRL-------TKPAKgklfyvpQRPyMTLgTLRDQIIYP- 538

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  90 MTAEQNVAFGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSaldaAVR 169
Cdd:TIGR00954 539 DSSEDMKRRGLSDKDLEQILDNVQLTHILEREGGWSAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTS----AVS 614

                         170       180
                  ....*....|....*....|...
gi 1424145480 170 VTLREEIRRIQQQLGMTVIYVTH 192
Cdd:TIGR00954 615 VDVEGYMYRLCREFGITLFSVSH 637
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 28-213 2.06e-10

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 58.54  E-value: 2.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   28 RGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGH-ILLDQEEITTRPANRRPMGMVFqsyalfphmtaeqnvafglrlrrlp 106
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGvIYIDGEDILEEVLDQLLLIIVG------------------------- 55

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  107 palirqrceellalvglaerarSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIR-----RIQQ 181
Cdd:smart00382  56 ----------------------GKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrlllLLKS 113

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1424145480  182 QLGMTVIYVTHDQEEalAISGRIAVMARGRLE 213
Cdd:smart00382 114 EKNLTVILTTNDEKD--LGPALLRRRFDRRIV 143
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 26-206 2.11e-10

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 59.51  E-value: 2.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  26 VERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPanrrpmgmvfqsyalfphmtaeQNVafglrlrrl 105
Cdd:cd03222    22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPVYKP----------------------QYI--------- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 106 ppalirqrceellalvglaerarsyphQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGM 185
Cdd:cd03222    71 ---------------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKK 123

                         170       180
                  ....*....|....*....|.
gi 1424145480 186 TVIYVTHDQEEALAISGRIAV 206
Cdd:cd03222   124 TALVVEHDLAVLDYLSDRIHV 144
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 29-193 2.39e-10

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 60.46  E-value: 2.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  29 GEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPANRrpmGMVFQSYalFPHMTAE--------QNVafgl 100
Cdd:cd03236    26 GQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPDWDEILDEFR---GSELQNY--FTKLLEGdvkvivkpQYV---- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 101 rlRRLPPA-------LIRQRCE--------ELLALVGLAERARSyphQLSGGQQQRVALARALAVEPKVLLLDEPLSALD 165
Cdd:cd03236    97 --DLIPKAvkgkvgeLLKKKDErgkldelvDQLELRHVLDRNID---QLSGGELQRVAIAAALARDADFYFFDEPSSYLD 171

                         170       180
                  ....*....|....*....|....*...
gi 1424145480 166 AAVRVTLREEIRRIQQQlGMTVIYVTHD 193
Cdd:cd03236   172 IKQRLNAARLIRELAED-DNYVLVVEHD 198
PTZ00243 PTZ00243
ABC transporter; Provisional
 22-225 2.50e-10

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 62.49  E-value: 2.50e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   22 ISLGVERGEFLTLLGPSGCGKTTVLRlvagfeqpdaghILLDQEEITT-RPANRRPMGMVFQSyALFPHMTAEQNVAF-- 98
Cdd:PTZ00243   679 VSVSVPRGKLTVVLGATGSGKSTLLQ------------SLLSQFEISEgRVWAERSIAYVPQQ-AWIMNATVRGNILFfd 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   99 GLRLRRLPPALirqRCEELLALV-----GLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLR 173
Cdd:PTZ00243   746 EEDAARLADAV---RVSQLEADLaqlggGLETEIGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGERVV 822

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1424145480  174 EEIrrIQQQL-GMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEIYRRP 225
Cdd:PTZ00243   823 EEC--FLGALaGKTRVLATH-QVHVVPRADYVVALGDGRVEFSGSSADFMRTS 872
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 4-173 2.65e-10

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 62.06  E-value: 2.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQeeiTTRpanrrpMGMVFQS 83
Cdd:PRK11819  325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIGE---TVK------LAYVDQS 395

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 Y-ALFPHMTAEQNVAFGLrlrrlppalirqrceELLALVGLAERARSY--------PHQ------LSGGQQQRVALARAL 148
Cdd:PRK11819  396 RdALDPNKTVWEEISGGL---------------DIIKVGNREIPSRAYvgrfnfkgGDQqkkvgvLSGGERNRLHLAKTL 460

                         170       180
                  ....*....|....*....|....*.
gi 1424145480 149 AVEPKVLLLDEPLSALDaavrV-TLR 173
Cdd:PRK11819  461 KQGGNVLLLDEPTNDLD----VeTLR 482
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 5-197 8.51e-10

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 60.41  E-value: 8.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAG-FEQPDAGHILL------DQEEITTRpanRRPM 77
Cdd:PRK10938  262 VLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGdHPQGYSNDLTLfgrrrgSGETIWDI---KKHI 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  78 GMVFQSYalfpHM-----TAEQNV-------AFGLrLRRLPPALiRQRCEELLALVGLAERARSYP-HQLSGGQQQRVAL 144
Cdd:PRK10938  339 GYVSSSL----HLdyrvsTSVRNVilsgffdSIGI-YQAVSDRQ-QKLAQQWLDILGIDKRTADAPfHSLSWGQQRLALI 412

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 145 ARALAVEPKVLLLDEPLSALDAavrvTLREEIRRIQQQL---GMT-VIYVTHDQEEA 197
Cdd:PRK10938  413 VRALVKHPTLLILDEPLQGLDP----LNRQLVRRFVDVLiseGETqLLFVSHHAEDA 465
PLN03232 PLN03232
ABC transporter C family member; Provisional
 22-223 1.72e-09

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 59.99  E-value: 1.72e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGfEQPDAGhilldqeeiTTRPANRRPMGMVFQSYALFpHMTAEQNVAFGL- 100
Cdd:PLN03232   636 INLEIPVGSLVAIVGGTGEGKTSLISAMLG-ELSHAE---------TSSVVIRGSVAYVPQVSWIF-NATVRENILFGSd 704

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  101 ----RLRRLPPALIRQRCEELLA---LVGLAERARSyphqLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAV----- 168
Cdd:PLN03232   705 feseRYWRAIDVTALQHDLDLLPgrdLTEIGERGVN----ISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVahqvf 780

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480  169 RVTLREEIRriqqqlGMTVIYVThDQEEALAISGRIAVMARGRLEQLGTPEEIYR 223
Cdd:PLN03232   781 DSCMKDELK------GKTRVLVT-NQLHFLPLMDRIILVSEGMIKEEGTFAELSK 828
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 5-195 1.72e-09

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 59.58  E-value: 1.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   5 ELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQE-EITtrpanrrpmgmVFQS 83
Cdd:PRK11147  321 EMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTKlEVA-----------YFDQ 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  84 Y--ALFPHMTAEQNVAFGL-------RLRRL---------PPalirqrceellalvglaERARSYPHQLSGGQQQRVALA 145
Cdd:PRK11147  390 HraELDPEKTVMDNLAEGKqevmvngRPRHVlgylqdflfHP-----------------KRAMTPVKALSGGERNRLLLA 452

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1424145480 146 RALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQqlgmTVIYVTHDQE 195
Cdd:PRK11147  453 RLFLKPSNLLILDEPTNDLDVETLELLEELLDSYQG----TVLLVSHDRQ 498
PLN03130 PLN03130
ABC transporter C family member; Provisional
 22-221 1.75e-09

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 59.75  E-value: 1.75e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGfEQP---DAGHILldqeeittrpanRRPMGMVFQSYALFpHMTAEQNVAF 98
Cdd:PLN03130   636 INLDVPVGSLVAIVGSTGEGKTSLISAMLG-ELPprsDASVVI------------RGTVAYVPQVSWIF-NATVRDNILF 701

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   99 GL-----RLRRLPPALIRQRCEELLA---LVGLAERARSyphqLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAV-- 168
Cdd:PLN03130   702 GSpfdpeRYERAIDVTALQHDLDLLPggdLTEIGERGVN----ISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVgr 777

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480  169 ---RVTLREEIRriqqqlGMTVIYVThDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PLN03130   778 qvfDKCIKDELR------GKTRVLVT-NQLHFLSQVDRIILVHEGMIKEEGTYEEL 826
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 22-167 1.79e-09

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 58.33  E-value: 1.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeeittRPANRrpMGMVFQSYALFPHmTAEQNVAFGLR 101
Cdd:cd03291    56 INLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI---------KHSGR--ISFSSQFSWIMPG-TIKENIIFGVS 123

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 102 LRRLPPALIRQRCEELLALVGLAERARSYPHQ----LSGGQQQRVALARALAVEPKVLLLDEPLSALDAA 167
Cdd:cd03291   124 YDEYRYKSVVKACQLEEDITKFPEKDNTVLGEggitLSGGQRARISLARAVYKDADLYLLDSPFGYLDVF 193
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 9-193 1.87e-09

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 59.36  E-value: 1.87e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   9 LTKSFGKTRAV-ERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGhilldqeeiTTRPANRRPMGMVFQSYALF 87
Cdd:PRK11819   12 VSKVVPPKKQIlKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEG---------EARPAPGIKVGYLPQEPQLD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  88 PHMTAEQNVAFGLR-----LRRL---------PPA----LI-RQ-RCEELLALVGLA------ERA----RSYP-----H 132
Cdd:PRK11819   83 PEKTVRENVEEGVAevkaaLDRFneiyaayaePDAdfdaLAaEQgELQEIIDAADAWdldsqlEIAmdalRCPPwdakvT 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1424145480 133 QLSGGQQQRVALARALAVEPKVLLLDEPLSALDAavrvtlrEEIRRIQQQL----GmTVIYVTHD 193
Cdd:PRK11819  163 KLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDA-------ESVAWLEQFLhdypG-TVVAVTHD 219
GguA NF040905
sugar ABC transporter ATP-binding protein;
134-212 2.02e-09

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 59.03  E-value: 2.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 134 LSGGQQQRVALARALAVEPKVLLLDEPLSALDaavrVTLREEIRRIQQQL---GMTVIYVTHDQEEALAISGRIAVMARG 210
Cdd:NF040905  405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGID----VGAKYEIYTIINELaaeGKGVIVISSELPELLGMCDRIYVMNEG 480


                  ..
gi 1424145480 211 RL 212
Cdd:NF040905  481 RI 482
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 16-176 2.64e-09

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 59.15  E-value: 2.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   16 TRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIlldqeeittRPANRrpMGMVFQSYALFPHmTAEQN 95
Cdd:TIGR01271  439 TPVLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI---------KHSGR--ISFSPQTSWIMPG-TIKDN 506

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   96 VAFGLRLRRLPPALIRQRC--EELLALvgLAERARSYPHQ----LSGGQQQRVALARALAVEPKVLLLDEPLSALDaavr 169
Cdd:TIGR01271  507 IIFGLSYDEYRYTSVIKACqlEEDIAL--FPEKDKTVLGEggitLSGGQRARISLARAVYKDADLYLLDSPFTHLD---- 580


                   ....*..
gi 1424145480  170 VTLREEI 176
Cdd:TIGR01271  581 VVTEKEI 587
PLN03232 PLN03232
ABC transporter C family member; Provisional
 22-229 2.95e-09

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 59.22  E-value: 2.95e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFPHMT-------A 92
Cdd:PLN03232  1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTdlRRVLSIIPQSPVLFSGTVrfnidpfS 1334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   93 EQNVAfglrlrRLPPALIRQRCEELLAL--VGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSAL----DA 166
Cdd:PLN03232  1335 EHNDA------DLWEALERAHIKDVIDRnpFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVdvrtDS 1408

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480  167 AVRVTLREEIRriqqqlGMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVF 229
Cdd:PLN03232  1409 LIQRTIREEFK------SCTMLVIAH-RLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAF 1464
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 134-193 1.07e-08

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 54.25  E-value: 1.07e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 134 LSGGQQQRVALARALAVEPK--VLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHD 193
Cdd:cd03238    88 LSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDINQLLEVIKGLIDL-GNTVILIEHN 148
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 36-183 2.28e-08

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 53.72  E-value: 2.28e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  36 GPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPanrRP-MGMVFQSYALFPHMTAEQNVAFGLRL----RRLPPALI 110
Cdd:PRK13541   33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIA---KPyCTYIGHNLGLKLEMTVFENLKFWSEIynsaETLYAAIH 109

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 111 RQRCEELlalvgLAERARSyphqLSGGQQQRVALARALAVEPKVLLLDEplsaldaaVRVTLREEIRRIQQQL 183
Cdd:PRK13541  110 YFKLHDL-----LDEKCYS----LSSGMQKIVAIARLIACQSDLWLLDE--------VETNLSKENRDLLNNL 165
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 22-192 2.29e-08

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 56.19  E-value: 2.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEiTTRPAN----RRPMGMVFQSYALFPHmTAEQNVA 97
Cdd:PTZ00265   404 LNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDSH-NLKDINlkwwRSKIGVVSQDPLLFSN-SIKNNIK 481

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   98 FGLRLRRLPPAL--------------------IRQRCEELLALV-------GLAERARSY-------------------- 130
Cdd:PTZ00265   482 YSLYSLKDLEALsnyynedgndsqenknkrnsCRAKCAGDLNDMsnttdsnELIEMRKNYqtikdsevvdvskkvlihdf 561

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480  131 ---------------PHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQLGMTVIYVTH 192
Cdd:PTZ00265   562 vsalpdkyetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAH 638
PLN03073 PLN03073
ABC transporter F family; Provisional
 22-165 2.79e-08

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 55.64  E-value: 2.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILldqeeittRPANRRpmgmvfqsYALFphmtaEQNVAFGLR 101
Cdd:PLN03073  528 LNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVF--------RSAKVR--------MAVF-----SQHHVDGLD 586

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 102 LRRLP--------PALIRQRCEELLALVGLAERARSYP-HQLSGGQQQRVALARALAVEPKVLLLDEPLSALD 165
Cdd:PLN03073  587 LSSNPllymmrcfPGVPEQKLRAHLGSFGVTGNLALQPmYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD 659
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 27-200 3.12e-08

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 55.56  E-value: 3.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  27 ERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHIL--LDQEEITTRpanrrpmgmvFQSYALFPHMtaeQNVAFGlRLR- 103
Cdd:COG1245    97 KKGKVTGILGPNGIGKSTALKILSGELKPNLGDYDeePSWDEVLKR----------FRGTELQDYF---KKLANG-EIKv 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 104 --------RLPPAL---IRQRCE------------ELLALVGLAERARSyphQLSGGQQQRVALARALAVEPKVLLLDEP 160
Cdd:COG1245   163 ahkpqyvdLIPKVFkgtVRELLEkvdergkldelaEKLGLENILDRDIS---ELSGGELQRVAIAAALLRDADFYFFDEP 239

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1424145480 161 LSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDqeeaLAI 200
Cdd:COG1245   240 SSYLDIYQRLNVARLIRELAEE-GKYVLVVEHD----LAI 274
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 32-195 3.21e-08

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 53.38  E-value: 3.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  32 LTLL-GPSGCGKTTVLR--LVAGF-EQP---DAGHILLD---------QEEITTRPANRRPMgMVFQSYALFphmtaeQN 95
Cdd:cd03240    24 LTLIvGQNGAGKTTIIEalKYALTgELPpnsKGGAHDPKliregevraQVKLAFENANGKKY-TITRSLAIL------EN 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  96 VAFglrlrrlppalIRQrcEELLALVgLAERARsyphqLSGGQQQ------RVALARALAVEPKVLLLDEPLSALDAA-V 168
Cdd:cd03240    97 VIF-----------CHQ--GESNWPL-LDMRGR-----CSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEEnI 157

                         170       180
                  ....*....|....*....|....*..
gi 1424145480 169 RVTLREEIRRIQQQLGMTVIYVTHDQE 195
Cdd:cd03240   158 EESLAEIIEERKSQKNFQLIVITHDEE 184
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
18-221 1.10e-07

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 52.51  E-value: 1.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  18 AVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEeittrpanrrpMGMVFQSYALFPHMTAEQNVA 97
Cdd:PRK13546   39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE-----------VSVIAISAGLSGQLTGIENIE 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  98 FGLRLRRLPPALIRQRCEELLALVGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIR 177
Cdd:PRK13546  108 FKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIY 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1424145480 178 RIQQQlGMTVIYVTHDQEEALAISGRIAVMARGRLEQLGTPEEI 221
Cdd:PRK13546  188 EFKEQ-NKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDV 230
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 26-192 1.36e-07

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 51.48  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  26 VERGEFLTLLGPSGCGKTTVLRLVAGfeQPDAGHI----LLDQEEITtrPANRRPMGMVFQSYALFPHMTAEQNVAFGLR 101
Cdd:cd03232    30 VKPGTLTALMGESGAGKTTLLDVLAG--RKTAGVItgeiLINGRPLD--KNFQRSTGYVEQQDVHSPNLTVREALRFSAL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 102 LRrlppalirqrceellalvglaerarsyphQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQ 181
Cdd:cd03232   106 LR-----------------------------GLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKLAD 156

                         170
                  ....*....|.
gi 1424145480 182 QlGMTVIYVTH 192
Cdd:cd03232   157 S-GQAILCTIH 166
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 4-194 1.66e-07

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 51.95  E-value: 1.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGfeQPD----AGHILLDQEEITTRPANRRPMGM 79
Cdd:CHL00131    8 LEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG--HPAykilEGDILFKGESILDLEPEERAHLG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  80 VFQSYALFPHMTAEQNVAFgLRL----RR-------LPPALIRQRCEELLALVGLAER--ARSYPHQLSGGQQQRVALAR 146
Cdd:CHL00131   86 IFLAFQYPIEIPGVSNADF-LRLaynsKRkfqglpeLDPLEFLEIINEKLKLVGMDPSflSRNVNEGFSGGEKKRNEILQ 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1424145480 147 ALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQ 194
Cdd:CHL00131  165 MALLDSELAILDETDSGLDIDALKIIAEGINKLMTS-ENSIILITHYQ 211
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
133-200 2.50e-07

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 52.50  E-value: 2.50e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 133 QLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQqlGMTVIYVTHDqeeaLAI 200
Cdd:PRK13409  212 ELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQRLNVARLIRELAE--GKYVLVVEHD----LAV 273
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 29-211 3.86e-07

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 52.42  E-value: 3.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   29 GEFLTLLGPSGCGKTTVLRLVA----GFEQPDAGHIL---LDQEEIttRPANRRPMGMVFQSYALFPHMTAEQNVAFGLR 101
Cdd:TIGR00956   87 GELTVVLGRPGSGCSTLLKTIAsntdGFHIGVEGVITydgITPEEI--KKHYRGDVVYNAETDVHFPHLTVGETLDFAAR 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  102 LR----RlPPALIRQRCEELLALVGLAERARSYPHQ----------LSGGQQQRVALARALAVEPKVLLLDEPLSALDAA 167
Cdd:TIGR00956  165 CKtpqnR-PDGVSREEYAKHIADVYMATYGLSHTRNtkvgndfvrgVSGGERKRVSIAEASLGGAKIQCWDNATRGLDSA 243

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1424145480  168 vrvTLREEIRRIQQQ---LGMTVIyVTHDQ--EEALAISGRIAVMARGR 211
Cdd:TIGR00956  244 ---TALEFIRALKTSaniLDTTPL-VAIYQcsQDAYELFDKVIVLYEGY 288
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 4-194 1.19e-06

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 50.55  E-value: 1.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLD---------QEEITTRPANR 74
Cdd:PRK10636  313 LKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAkgiklgyfaQHQLEFLRADE 392

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  75 RPMgmvfqsyalfPHMTaeqnvafglrlrRLPPALIRQRCEELLALVGL-AERARSYPHQLSGGQQQRVALARALAVEPK 153
Cdd:PRK10636  393 SPL----------QHLA------------RLAPQELEQKLRDYLGGFGFqGDKVTEETRRFSGGEKARLVLALIVWQRPN 450

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1424145480 154 VLLLDEPLSALDAAVRVTLREEIRRIQQQLgmtvIYVTHDQ 194
Cdd:PRK10636  451 LLLLDEPTNHLDLDMRQALTEALIDFEGAL----VVVSHDR 487
PLN03130 PLN03130
ABC transporter C family member; Provisional
 22-229 1.74e-06

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 50.51  E-value: 1.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFPHMT-------A 92
Cdd:PLN03130  1258 LSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMdlRKVLGIIPQAPVLFSGTVrfnldpfN 1337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   93 EQNVAfglrlrRLPPALIRQRCEELLAL--VGLAERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSAL----DA 166
Cdd:PLN03130  1338 EHNDA------DLWESLERAHLKDVIRRnsLGLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVdvrtDA 1411

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480  167 AVRVTLREEIRriqqqlGMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVF 229
Cdd:PLN03130  1412 LIQKTIREEFK------SCTMLIIAH-RLNTIIDCDRILVLDAGRVVEFDTPENLLSNEGSAF 1467
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 132-195 3.24e-06

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 46.97  E-value: 3.24e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480 132 HQLSGGQQQRVALARALA---VEPKVL-LLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDQE 195
Cdd:cd03227    76 LQLSGGEKELSALALILAlasLKPRPLyILDEIDRGLDPRDGQALAEAILEHLVK-GAQVIVITHLPE 142
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 4-214 6.08e-06

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 47.54  E-value: 6.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSF--GKTRAVERISLGVERGEFLTLLGPSGCGKTTV----LRLVAgfeqpDAGHILLDQEEITTRPAN--RR 75
Cdd:cd03289     3 MTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLlsafLRLLN-----TEGDIQIDGVSWNSVPLQkwRK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  76 PMGMVFQSYALFPhmtaeqnvafGLRLRRLPPaLIRQRCEELLAL---VGLAERARSYPHQL-----------SGGQQQR 141
Cdd:cd03289    78 AFGVIPQKVFIFS----------GTFRKNLDP-YGKWSDEEIWKVaeeVGLKSVIEQFPGQLdfvlvdggcvlSHGHKQL 146

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480 142 VALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRriQQQLGMTVIYVTHdQEEALAISGRIAVMARGRLEQ 214
Cdd:cd03289   147 MCLARSVLSKAKILLLDEPSAHLDPITYQVIRKTLK--QAFADCTVILSEH-RIEAMLECQRFLVIEENKVRQ 216
PLN03073 PLN03073
ABC transporter F family; Provisional
 120-195 6.70e-06

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 48.32  E-value: 6.70e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1424145480 120 LVGL---AERARSYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSALDAAVRVTLREEIRRIQQqlgmTVIYVTHDQE 195
Cdd:PLN03073  328 LAGLsftPEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLLKWPK----TFIVVSHARE 402
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 22-229 1.11e-05

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 47.63  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFP---HMT----- 91
Cdd:TIGR00957 1305 INVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHdlRFKITIIPQDPVLFSgslRMNldpfs 1384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   92 --AEQNVAFGLRLRRLP------PALIRQRCEEllalvglaerarsYPHQLSGGQQQRVALARALAVEPKVLLLDEPLSA 163
Cdd:TIGR00957 1385 qySDEEVWWALELAHLKtfvsalPDKLDHECAE-------------GGENLSVGQRQLVCLARALLRKTKILVLDEATAA 1451

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1424145480  164 LDAAVRVTLREEIRriQQQLGMTVIYVTHDQEEALAISgRIAVMARGRLEQLGTPEEIYRRpRTVF 229
Cdd:TIGR00957 1452 VDLETDNLIQSTIR--TQFEDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNLLQQ-RGIF 1513
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 26-166 1.24e-05

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 47.41  E-value: 1.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   26 VERGEFLTLLGPSGCGKTTVLRLVAgfEQPDAGHILLDQEEITTRPAN---RRPMGMVFQSYALFPHMTAEQNVAFGLRL 102
Cdd:TIGR00956  786 VKPGTLTALMGASGAGKTTLLNVLA--ERVTTGVITGGDRLVNGRPLDssfQRSIGYVQQQDLHLPTSTVRESLRFSAYL 863

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1424145480  103 RRLPPALIRQRCE------ELL-------ALVGLAERArsyphqLSGGQQQRVALARALAVEPKVLL-LDEPLSALDA 166
Cdd:TIGR00956  864 RQPKSVSKSEKMEyveeviKLLemesyadAVVGVPGEG------LNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLDS 935
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 9-193 1.44e-05

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 47.19  E-value: 1.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   9 LTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEE-----------------ITTRP 71
Cdd:PRK15064    7 ITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNErlgklrqdqfafeeftvLDTVI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  72 ANRRPMGMVFQS----YALfPHMTAEQnvafGLRLRRLPPAL-------IRQRCEELLALVGLAERARSYP-HQLSGGQQ 139
Cdd:PRK15064   87 MGHTELWEVKQErdriYAL-PEMSEED----GMKVADLEVKFaemdgytAEARAGELLLGVGIPEEQHYGLmSEVAPGWK 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1424145480 140 QRVALARALAVEPKVLLLDEPLSALDAavrvtlrEEIRRIQQQLGM---TVIYVTHD 193
Cdd:PRK15064  162 LRVLLAQALFSNPDILLLDEPTNNLDI-------NTIRWLEDVLNErnsTMIIISHD 211
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 4-198 2.96e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 46.44  E-value: 2.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480    4 LELQELTKSFGKT-RAV-ERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDaGHILLD--QEEITTRPANRRPMGM 79
Cdd:TIGR01271 1218 MDVQGLTAKYTEAgRAVlQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDgvSWNSVTLQTWRKAFGV 1296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   80 VFQSYALFPhmtaeqnvafGLRLRRLPPaLIRQRCEELLAL---VGLAERARSYPHQL-----------SGGQQQRVALA 145
Cdd:TIGR01271 1297 IPQKVFIFS----------GTFRKNLDP-YEQWSDEEIWKVaeeVGLKSVIEQFPDKLdfvlvdggyvlSNGHKQLMCLA 1365

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1424145480  146 RALAVEPKVLLLDEPLSALDAAVRVTLREEIRriQQQLGMTVIYVTHDQEEAL 198
Cdd:TIGR01271 1366 RSILSKAKILLLDEPSAHLDPVTLQIIRKTLK--QSFSNCTVILSEHRVEALL 1416
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 4-194 3.65e-05

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 44.78  E-value: 3.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   4 LELQELTKSFGKTRAVERISLGVERGEFLTLLGPSGCGKTTVLRLVAGFE--QPDAGHILLDQEEITT-RPANRRPMG-- 78
Cdd:PRK09580    2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLElSPEDRAGEGif 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  79 MVFQSYALFPHMTAE---QNVAFGLRLRRLPPALIR----QRCEELLALVGLAER--ARSYPHQLSGGQQQRVALARALA 149
Cdd:PRK09580   82 MAFQYPVEIPGVSNQfflQTALNAVRSYRGQEPLDRfdfqDLMEEKIALLKMPEDllTRSVNVGFSGGEKKRNDILQMAV 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1424145480 150 VEPKVLLLDEPLSALDA-AVRV------TLREEIRriqqqlgmTVIYVTHDQ 194
Cdd:PRK09580  162 LEPELCILDESDSGLDIdALKIvadgvnSLRDGKR--------SFIIVTHYQ 205
PLN03140 PLN03140
ABC transporter G family member; Provisional
 25-192 3.67e-05

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 45.99  E-value: 3.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   25 GVERGEFLT-LLGPSGCGKTTVLRLVAGfeQPDAGHILLDQEeITTRPANR----RPMGMVFQSYALFPHMTAEQNVAFG 99
Cdd:PLN03140   901 GAFRPGVLTaLMGVSGAGKTTLMDVLAG--RKTGGYIEGDIR-ISGFPKKQetfaRISGYCEQNDIHSPQVTVRESLIYS 977

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  100 LRLRrLPPALIRQ-------RCEELLALVGLAERARSYP--HQLSGGQQQRVALARALAVEPKVLLLDEPLSALDA-AVR 169
Cdd:PLN03140   978 AFLR-LPKEVSKEekmmfvdEVMELVELDNLKDAIVGLPgvTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDArAAA 1056

                          170       180
                   ....*....|....*....|...
gi 1424145480  170 VTLREEirRIQQQLGMTVIYVTH 192
Cdd:PLN03140  1057 IVMRTV--RNTVDTGRTVVCTIH 1077
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 29-195 1.00e-04

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 44.39  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  29 GEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILL---------DQEEittrPANRRP-MGMVFQSYALFPHMTAEQNVA- 97
Cdd:PRK10636   27 GQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFpgnwqlawvNQET----PALPQPaLEYVIDGDREYRQLEAQLHDAn 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  98 ----------FGLRLRRLPPALIRQRCEELLALVGLAERARSYP-HQLSGGQQQRVALARALAVEPKVLLLDEPLSALDA 166
Cdd:PRK10636  103 erndghaiatIHGKLDAIDAWTIRSRAASLLHGLGFSNEQLERPvSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDL 182

                         170       180
                  ....*....|....*....|....*....
gi 1424145480 167 AVRVTLREEIRRIQQqlgmTVIYVTHDQE 195
Cdd:PRK10636  183 DAVIWLEKWLKSYQG----TLILISHDRD 207
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 117-195 1.72e-04

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 42.63  E-value: 1.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 117 LLALVGLAER--------------ARSYPhQLSGGQQQRVALARALAVEPKVLL--LDEPLSALDAAVRVTLREEIRRIq 180
Cdd:cd03270   108 LFARVGIRERlgflvdvglgyltlSRSAP-TLSGGEAQRIRLATQIGSGLTGVLyvLDEPSIGLHPRDNDRLIETLKRL- 185

                          90
                  ....*....|....*
gi 1424145480 181 QQLGMTVIYVTHDQE 195
Cdd:cd03270   186 RDLGNTVLVVEHDED 200
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 29-229 4.31e-04

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 41.82  E-value: 4.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  29 GEFLTLLGPSGCGKTTV----LRLVAGFEqpdaGHILLDQEEITTRPAN--RRPMGMVFQSYALFphmtaEQNVAFGLRL 102
Cdd:cd03288    47 GQKVGICGRTGSGKSSLslafFRMVDIFD----GKIVIDGIDISKLPLHtlRSRLSIILQDPILF-----SGSIRFNLDP 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 103 RRlppALIRQRCEELLALVGLAERARSYPHQL-----------SGGQQQRVALARALAVEPKVLLLDEPLSALDAAVrvt 171
Cdd:cd03288   118 EC---KCTDDRLWEALEIAQLKNMVKSLPGGLdavvteggenfSVGQRQLFCLARAFVRKSSILIMDEATASIDMAT--- 191

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424145480 172 lreeiRRIQQQLGM------TVIYVTHDQEEALAiSGRIAVMARGRLEQLGTPEEIYRRPRTVF 229
Cdd:cd03288   192 -----ENILQKVVMtafadrTVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLLAQEDGVF 249
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 134-204 4.77e-04

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 42.51  E-value: 4.77e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1424145480  134 LSGGQQQRVALARALAVEPK--VLLLDEPLSALDAAVRVTLREEIRRIQQQlGMTVIYVTHDqEEALAISGRI 204
Cdd:PRK00635   477 LSGGEQERTALAKHLGAELIgiTYILDEPSIGLHPQDTHKLINVIKKLRDQ-GNTVLLVEHD-EQMISLADRI 547
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 134-228 1.77e-03

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 40.77  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480 134 LSGGQQQRVALARALAVE-PKVL-LLDEPLSALDAAVRVTLREEIRRIqQQLGMTVIYVTHDqEEALAISGRIAVMAR-- 209
Cdd:TIGR00630 489 LSGGEAQRIRLATQIGSGlTGVLyVLDEPSIGLHQRDNRRLINTLKRL-RDLGNTLIVVEHD-EDTIRAADYVIDIGPga 566

                          90       100
                  ....*....|....*....|...
gi 1424145480 210 ----GRLEQLGTPEEIYRRPRTV 228
Cdd:TIGR00630 567 gehgGEVVASGTPEEILANPDSL 589
PTZ00243 PTZ00243
ABC transporter; Provisional
 22-251 5.78e-03

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 38.99  E-value: 5.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480   22 ISLGVERGEFLTLLGPSGCGKTTVLRLVAGFEQPDAGHILLDQEEITTRPAN--RRPMGMVFQSYALFPHmTAEQNVafg 99
Cdd:PTZ00243  1329 VSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRelRRQFSMIPQDPVLFDG-TVRQNV--- 1404

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  100 lrlrrlPPALIRQRCE--ELLALVGLAERARSYPHQL-----------SGGQQQRVALARALAVE-PKVLLLDEPLSALD 165
Cdd:PTZ00243  1405 ------DPFLEASSAEvwAALELVGLRERVASESEGIdsrvleggsnySVGQRQLMCMARALLKKgSGFILMDEATANID 1478

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424145480  166 AAVRvtlreeiRRIQQQL-----GMTVIYVTHdQEEALAISGRIAVMARGRLEQLGTPEEIYRRPRTVFvAGFVGASTRL 240
Cdd:PTZ00243  1479 PALD-------RQIQATVmsafsAYTVITIAH-RLHTVAQYDKIIVMDHGAVAEMGSPRELVMNRQSIF-HSMVEALGRS 1549

                          250
                   ....*....|.
gi 1424145480  241 SARLERAVEGR 251
Cdd:PTZ00243  1550 EAKRFLQLVGR 1560
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 36-68 6.42e-03

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 36.70  E-value: 6.42e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1424145480  36 GPSGCGKTTVLRLVA---GFEQPDAGhiLLDQEEIT 68
Cdd:cd02020     6 GPAGSGKSTVAKLLAkklGLPYLDTG--GIRTEEVG 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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