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Conserved domains on  [gi|1435803798|ref|WP_114546041|]
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CidA/LrgA family protein [Eggerthella sinensis]

Protein Classification

CidA/LrgA family protein( domain architecture ID 10003619)

CidA/LrgA family protein similar to Staphylococcus holin-like protein CidA that increases the activity of extracellular murein hydrolases, possibly by mediating their export via hole formation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YohJ COG1380
Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];
53-150 4.23e-12

Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];


:

Pssm-ID: 440990  Cd Length: 120  Bit Score: 59.74  E-value: 4.23e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435803798  53 GCALASVLPVHLPGNIVGMVLLLVLLGTGLVKARHVGDACDCLLDNMSLFFIPAGVAIMGCFSLLEGNAAKFALVCVVTT 132
Cdd:COG1380    15 GELLSRLLGLPIPGSVIGMLLLFLLLALGIIKLEWVEPGADFLLRHLSLLFVPAGVGVMNYLDLLSAEGLPILLAIVVST 94

                          90
                  ....*....|....*...
gi 1435803798 133 VLVFLATSYTVMLVSRLM 150
Cdd:COG1380    95 LLVLAVTGLVVQLLLRRK 112
 
Name Accession Description Interval E-value
YohJ COG1380
Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];
53-150 4.23e-12

Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];


Pssm-ID: 440990  Cd Length: 120  Bit Score: 59.74  E-value: 4.23e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435803798  53 GCALASVLPVHLPGNIVGMVLLLVLLGTGLVKARHVGDACDCLLDNMSLFFIPAGVAIMGCFSLLEGNAAKFALVCVVTT 132
Cdd:COG1380    15 GELLSRLLGLPIPGSVIGMLLLFLLLALGIIKLEWVEPGADFLLRHLSLLFVPAGVGVMNYLDLLSAEGLPILLAIVVST 94

                          90
                  ....*....|....*...
gi 1435803798 133 VLVFLATSYTVMLVSRLM 150
Cdd:COG1380    95 LLVLAVTGLVVQLLLRRK 112
LrgA pfam03788
LrgA family; This family is uncharacterized. It contains the protein LrgA that has been ...
 53-143 4.40e-10

LrgA family; This family is uncharacterized. It contains the protein LrgA that has been hypothesized to export murein hydrolases.


Pssm-ID: 461050  Cd Length: 94  Bit Score: 53.90  E-value: 4.40e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435803798  53 GCALASVLPVHLPGNIVGMVLLLVLLGTGLVKARHVGDACDCLLDNMSLFFIPAGVAIMGCFSLLEGNAAKFALVCVVTT 132
Cdd:pfam03788   4 GELLSRLLPLPIPGSVIGMLLLFLLLLTGIVKLEWVEEAADFLLRHMPLFFVPAGVGLMTYLDLLKAEGLPILVIIVVST 83

                          90
                  ....*....|.
gi 1435803798 133 VLVFLATSYTV 143
Cdd:pfam03788  84 VLVLAVTGLVV 94
PRK01821 PRK01821
hypothetical protein; Provisional
 53-117 1.59e-04

hypothetical protein; Provisional


Pssm-ID: 234983  Cd Length: 133  Bit Score: 39.60  E-value: 1.59e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1435803798  53 GCALASVLPVHLPGNIVGMVLLLVLLGTGLVKARHVGDACDCLLDNMSLFFIPAGVAIMGCFSLL 117
Cdd:PRK01821   25 GIFIASLLPITIPGSIIGMLILFVLLALQILPAKWVKPGCSLLIRYMALLFVPIGVGVMQYYDLL 89
 
Name Accession Description Interval E-value
YohJ COG1380
Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];
53-150 4.23e-12

Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];


Pssm-ID: 440990  Cd Length: 120  Bit Score: 59.74  E-value: 4.23e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435803798  53 GCALASVLPVHLPGNIVGMVLLLVLLGTGLVKARHVGDACDCLLDNMSLFFIPAGVAIMGCFSLLEGNAAKFALVCVVTT 132
Cdd:COG1380    15 GELLSRLLGLPIPGSVIGMLLLFLLLALGIIKLEWVEPGADFLLRHLSLLFVPAGVGVMNYLDLLSAEGLPILLAIVVST 94

                          90
                  ....*....|....*...
gi 1435803798 133 VLVFLATSYTVMLVSRLM 150
Cdd:COG1380    95 LLVLAVTGLVVQLLLRRK 112
LrgA pfam03788
LrgA family; This family is uncharacterized. It contains the protein LrgA that has been ...
 53-143 4.40e-10

LrgA family; This family is uncharacterized. It contains the protein LrgA that has been hypothesized to export murein hydrolases.


Pssm-ID: 461050  Cd Length: 94  Bit Score: 53.90  E-value: 4.40e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435803798  53 GCALASVLPVHLPGNIVGMVLLLVLLGTGLVKARHVGDACDCLLDNMSLFFIPAGVAIMGCFSLLEGNAAKFALVCVVTT 132
Cdd:pfam03788   4 GELLSRLLPLPIPGSVIGMLLLFLLLLTGIVKLEWVEEAADFLLRHMPLFFVPAGVGLMTYLDLLKAEGLPILVIIVVST 83

                          90
                  ....*....|.
gi 1435803798 133 VLVFLATSYTV 143
Cdd:pfam03788  84 VLVLAVTGLVV 94
PRK01821 PRK01821
hypothetical protein; Provisional
 53-117 1.59e-04

hypothetical protein; Provisional


Pssm-ID: 234983  Cd Length: 133  Bit Score: 39.60  E-value: 1.59e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1435803798  53 GCALASVLPVHLPGNIVGMVLLLVLLGTGLVKARHVGDACDCLLDNMSLFFIPAGVAIMGCFSLL 117
Cdd:PRK01821   25 GIFIASLLPITIPGSIIGMLILFVLLALQILPAKWVKPGCSLLIRYMALLFVPIGVGVMQYYDLL 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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