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Conserved domains on  [gi|1441214933|ref|WP_114840058|]
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ABC transporter ATP-binding protein [Halarcobacter bivalviorum]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467437)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including Fe(3+) ions and polyamines such as spermidine and putrescine

CATH:  3.40.50.300
EC:  7.-.-.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0005524|GO:0016887
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 20-215 7.42e-82

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


:

Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 250.40  E-value: 7.42e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:COG3842    23 DVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPdSGRILLDGRDVTG----LPPEKRNVGMVFQDYALFPHLTVAENV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:COG3842    99 AFglrmrgVPKAeiRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREEL 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:COG3842   179 RRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEI 223
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 20-215 7.42e-82

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 250.40  E-value: 7.42e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:COG3842    23 DVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPdSGRILLDGRDVTG----LPPEKRNVGMVFQDYALFPHLTVAENV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:COG3842    99 AFglrmrgVPKAeiRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREEL 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:COG3842   179 RRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEI 223
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 20-210 7.44e-74

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 225.09  E-value: 7.44e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:cd03259    18 DLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERpDSGEILIDGRDVTG----VPPERRNIGMVFQDYALFPHLTVAENI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF------VNKDKELANH--LLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:cd03259    94 AFglklrgVPKAEIRARVreLLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLREELREEL 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03259   174 KELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 2-216 2.00e-58

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 190.32  E-value: 2.00e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   2 IKIEIKKELhgsnGVMNLDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQD--EKEFLPVQKRK 78
Cdd:TIGR02142   1 LSARFSKRL----GDFSLDADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDeGEIVLNGRTLFDsrKGIFLPPEKRR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  79 IGFVFQDYALFPNMTVLENLFFVNKD---KELANHLLEITELW---ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMD 152
Cdd:TIGR02142  77 IGYVFQEARLFPHLSVRGNLRYGMKRarpSERRISFERVIELLgigHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMD 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 153 EPLSALDptmrIKLQDEIL----QLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:TIGR02142 157 EPLAALD----DPRKYEILpyleRLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVW 220
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
12-215 1.42e-56

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 185.92  E-value: 1.42e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  12 GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFP 90
Cdd:PRK09452   25 DGKEVIS-NLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPdSGRIMLDGQDITH----VPAENRHVNTVFQSYALFP 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLENLFFVNKDKELANHllEITE----------LWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP 160
Cdd:PRK09452  100 HMTVFENVAFGLRMQKTPAA--EITPrvmealrmvqLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDY 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 161 TMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK09452  178 KLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREI 232
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
20-215 1.60e-50

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 169.49  E-value: 1.60e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEiwqdEKEFLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:NF040840   18 DISLEVKEGEYFIILGPSGAGKTVLLELIAGIwPPDSGKIYLDGK----DITNLPPEKRGIAYVYQNYMLFPHKTVFENI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFVNK-----DKELANHLLEITELW---ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:NF040840   94 AFGLKlrkvpKEEIERKVKEIMELLgisHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDELIREM 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:NF040840  174 KRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREV 218
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 20-156 1.89e-38

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 132.39  E-value: 1.89e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDN-EIWQDEKEFLpvqKRKIGFVFQDYALFPNMTVLEN 97
Cdd:pfam00005   3 NVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSpTEGTILLDGqDLTDDERKSL---RKEIGYVFQDPQLFPRLTVREN 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1441214933  98 LFFVNKDKEL--------ANHLLEITELWELKNRL----PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:pfam00005  80 LRLGLLLKGLskrekdarAEEALEKLGLGDLADRPvgerPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
20-191 7.86e-19

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 81.90  E-value: 7.86e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVdneiwqdekeflpVQKRKIGFVFQDYAL---FPnMTVL 95
Cdd:NF040873   10 GVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRpTSGTVRR-------------AGGARVAYVPQRSEVpdsLP-LTVR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 E----NLF--------FVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:NF040873   76 DlvamGRWarrglwrrLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESR 155

                         170       180
                  ....*....|....*....|....*...
gi 1441214933 164 IKLQDEILQLHKEfETTTILVSHDPSEI 191
Cdd:NF040873  156 ERIIALLAEEHAR-GATVVVVTHDLELV 182
GguA NF040905
sugar ABC transporter ATP-binding protein;
15-208 4.41e-14

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 71.74  E-value: 4.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  15 GVMNL-DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA---QGIIKVDNEiwqdEKEFLPV---QKRKIGFVFQDYA 87
Cdd:NF040905   13 GVKALdDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHgsyEGEILFDGE----VCRFKDIrdsEALGIVIIHQELA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  88 LFPNMTVLENLFFVNK-------DKELANH----LLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:NF040905   89 LIPYLSIAENIFLGNErakrgviDWNETNRrareLLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDEPTA 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 157 ALDPTMRIKLQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVD 208
Cdd:NF040905  169 ALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVLRDGRTIE 219
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
96-221 8.26e-13

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 67.45  E-value: 8.26e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLFFVNKDKEL--------ANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:NF000106  105 ENLYMIGR*LDLsrkdararADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVW 184

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 168 DEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKTSG 221
Cdd:NF000106  185 DEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVGG 237
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
20-219 6.86e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 62.45  E-value: 6.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDEKEFLPVQKRkIGFVFQDYA--LFPNMTVLE 96
Cdd:NF033858   19 DVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQqGRVEVLGGDMADARHRRAVCPR-IAYMPQGLGknLYPTLSVFE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NL-FFVNkdkeLANH-----------LLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:NF033858   98 NLdFFGR----LFGQdaaerrrrideLLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRR 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 165 KLQDEILQLHKEFETTTILVS---HDPSEIYklsNRVIVLKDGKIVDDGTAKSVLLKT 219
Cdd:NF033858  174 QFWELIDRIRAERPGMSVLVAtayMEEAERF---DWLVAMDAGRVLATGTPAELLART 228
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
76-163 3.96e-07

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 50.89  E-value: 3.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  76 KRKIGFVFQDYALFPNMTVLENL------FFVNKDK--ELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPK 147
Cdd:NF033858  338 RRRVGYMSQAFSLYGELTVRQNLelharlFHLPAAEiaARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPE 417

                          90
                  ....*....|....*.
gi 1441214933 148 LLLMDEPLSALDPTMR 163
Cdd:NF033858  418 LLILDEPTSGVDPVAR 433
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 27-191 8.45e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 47.75  E-value: 8.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   27 SKDFVALTGLSGSGKTTLLRSLAGLEKAQGiikvdneiwqdekeflpvqkrkigfvfqdyalfpnmtvlENLFFVNKDKE 106
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPG---------------------------------------GGVIYIDGEDI 41

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  107 LANHLLEITElwELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI-----LQLHKEFETTT 181
Cdd:smart00382  42 LEEVLDQLLL--IIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEelrllLLLKSEKNLTV 119

                          170
                   ....*....|
gi 1441214933  182 ILVSHDPSEI 191
Cdd:smart00382 120 ILTTNDEKDL 129
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 20-215 7.42e-82

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 250.40  E-value: 7.42e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:COG3842    23 DVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPdSGRILLDGRDVTG----LPPEKRNVGMVFQDYALFPHLTVAENV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:COG3842    99 AFglrmrgVPKAeiRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREEL 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:COG3842   179 RRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEI 223
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 20-216 9.10e-77

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 236.97  E-value: 9.10e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWqdeKEFLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:COG1118    20 DVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPdSGRIVLNGRDL---FTNLPPRERRVGFVFQHYALFPHMTVAENI 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:COG1118    97 AFglrvrpPSKAeiRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFGALDAKVRKELRRWL 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1118   177 RRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVY 222
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 20-210 7.44e-74

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 225.09  E-value: 7.44e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:cd03259    18 DLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERpDSGEILIDGRDVTG----VPPERRNIGMVFQDYALFPHLTVAENI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF------VNKDKELANH--LLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:cd03259    94 AFglklrgVPKAEIRARVreLLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLREELREEL 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03259   174 KELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 20-211 1.17e-73

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 229.19  E-value: 1.17e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:COG3839    21 DIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPtSGEILIGGRDVTD----LPPKDRNIAMVFQSYALYPHMTVYENI 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:COG3839    97 AFplklrkVPKAeiDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEI 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:COG3839   177 KRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGT 217
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 1-216 2.98e-73

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 228.45  E-value: 2.98e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEIKKELHGSNgvmnLDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDEKE--FLPVQKR 77
Cdd:COG4148     2 MLEVDFRLRRGGFT----LDVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPdSGRIRLGGEVLQDSARgiFLPPHRR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  78 KIGFVFQDYALFPNMTVLENLFF------VNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLM 151
Cdd:COG4148    78 RIGYVFQEARLFPHLSVRGNLLYgrkrapRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLM 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933 152 DEPLSALDPTMRiklqDEIL----QLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG4148   158 DEPLAALDLARK----AEILpyleRLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVL 222
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 20-209 1.38e-72

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 223.43  E-value: 1.38e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdekeflPVQK--RKIGFVFQDYALFPNMTVLE 96
Cdd:COG1116    29 DVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPtSGEVLVDGK---------PVTGpgPDRGVVFQEPALLPWLTVLD 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:COG1116   100 NVALglelrgVPKAerRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLLMDEPFGALDALTRERLQD 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1441214933 169 EILQLHKEFETTTILVSHDPSE-IYkLSNRVIVLKD--GKIVDD 209
Cdd:COG1116   180 ELLRLWQETGKTVLFVTHDVDEaVF-LADRVVVLSArpGRIVEE 222
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 1-210 2.78e-72

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 221.01  E-value: 2.78e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEIKKELHGsngvMNLDVNLDIrSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQD--EKEFLPVQKR 77
Cdd:cd03297     1 MLCVDIEKRLPD----FTLKIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDgGTIVLNGTVLFDsrKKINLPPQQR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  78 KIGFVFQDYALFPNMTVLENLFFV------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLM 151
Cdd:cd03297    76 KIGLVFQQYALFPHLNVRENLAFGlkrkrnREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLL 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933 152 DEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03297   156 DEPFSALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 20-211 2.46e-65

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 204.01  E-value: 2.46e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:cd03300    18 GVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPtSGEILLDGKDITN----LPPHKRPVNTVFQNYALFPHLTVFENI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:cd03300    94 AFglrlkkLPKAeiKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKLRKDMQLEL 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:cd03300   174 KRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 19-205 2.88e-65

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 202.03  E-value: 2.88e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  19 LDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIWQDEKEFLPVQKRKIGFVFQDYALFPNMTVLEN 97
Cdd:cd03229    17 NDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEpDSGSILIDGEDLTDLEDELPPLRRRIGMVFQDFALFPHLTVLEN 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFvnkdkelanhlleitelwelknrlpnSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEF 177
Cdd:cd03229    97 IAL--------------------------GLSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQL 150

                         170       180
                  ....*....|....*....|....*...
gi 1441214933 178 ETTTILVSHDPSEIYKLSNRVIVLKDGK 205
Cdd:cd03229   151 GITVVLVTHDLDEAARLADRVVVLRDGK 178
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 20-209 1.47e-63

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 198.85  E-value: 1.47e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEiwqdekeflPVQ--KRKIGFVFQDYALFPNMTVLE 96
Cdd:cd03293    22 DISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTsGEVLVDGE---------PVTgpGPDRGYVFQQDALLPWLTVLD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:cd03293    93 NVALglelqgVPKAeaRERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDEPFSALDALTREQLQE 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1441214933 169 EILQLHKEFETTTILVSHDPSE-IYkLSNRVIVL--KDGKIVDD 209
Cdd:cd03293   173 ELLDIWRETGKTVLLVTHDIDEaVF-LADRVVVLsaRPGRIVAE 215
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
20-209 1.57e-63

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 199.11  E-value: 1.57e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDN-EIWQ-DEKEFLPVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:COG1136    26 GVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPtSGEVLIDGqDISSlSERELARLRRRHIGFVFQFFNLLPELTALE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NL--------FFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:COG1136   106 NValplllagVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLE 185

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1441214933 169 EILQLHKEFETTTILVSHDPsEIYKLSNRVIVLKDGKIVDD 209
Cdd:COG1136   186 LLRELNRELGTTIVMVTHDP-ELAARADRVIRLRDGRIVSD 225
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 20-206 6.92e-62

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 194.63  E-value: 6.92e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDN-EIWQ-DEKEFLPVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:cd03255    22 GVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPtSGEVRVDGtDISKlSEKELAAFRRRHIGFVFQSFNLLPDLTALE 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 N----LFFVNK----DKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:cd03255   102 NvelpLLLAGVpkkeRRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPKIILADEPTGNLDSETGKEVME 181

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1441214933 169 EILQLHKEFETTTILVSHDPsEIYKLSNRVIVLKDGKI 206
Cdd:cd03255   182 LLRELNKEAGTTIVVVTHDP-ELAEYADRIIELRDGKI 218
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 3-216 1.24e-61

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 195.94  E-value: 1.24e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   3 KIEIKKELHGSNGVMnlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNE--IWQDEKEFLPVQKRKI 79
Cdd:cd03294    27 KEEILKKTGQTVGVN--DVSLDVREGEIFVIMGLSGSGKSTLLRCINRLiEPTSGKVLIDGQdiAAMSRKELRELRRKKI 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  80 GFVFQDYALFPNMTVLENLFF------VNKDK--ELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLM 151
Cdd:cd03294   105 SMVFQSFALLPHRTVLENVAFglevqgVPRAEreERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLM 184

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 152 DEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:cd03294   185 DEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEIL 249
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 20-229 1.34e-61

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 194.87  E-value: 1.34e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdEKEFLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:cd03296    20 DVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPdSGTILFGGE----DATDVPVQERNVGFVFQHYALFRHMTVFDNV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF----------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKL 166
Cdd:cd03296    96 AFglrvkprserPPEAeiRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKVRKEL 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 167 QDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKTSGSAKFSFEG 229
Cdd:cd03296   176 RRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFLG 238
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
20-216 1.14e-60

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 192.20  E-value: 1.14e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNE-IWQDEKEFlpvqKRKIGFVFQDYALFPNMTVLEN 97
Cdd:COG1131    18 GVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTsGEVRVLGEdVARDPAEV----RRRIGYVPQEPALYPDLTVREN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFV--------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:COG1131    94 LRFFarlyglprKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTSGLDPEARRELWEL 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1441214933 170 ILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1131   174 LRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELK 219
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 20-216 1.89e-59

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 188.70  E-value: 1.89e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQdeKEFLPVQKRKIGFVFQ--DYALFpNMTVLE 96
Cdd:COG1122    19 DVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTsGEVLVDGKDIT--KKNLRELRRKVGLVFQnpDDQLF-APTVEE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:COG1122    96 DVAFgpenlgLPREeiRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLE 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1441214933 169 EILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1122   176 LLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVF 222
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 20-207 1.68e-58

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 185.92  E-value: 1.68e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:cd03301    18 DLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPtSGRIYIGGRDVTD----LPPKDRDIAMVFQNYALYPHMTVYDNI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF-----------VNKDKELANHLLEITELWelkNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:cd03301    94 AFglklrkvpkdeIDERVREVAELLQIEHLL---DRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQMR 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1441214933 168 DEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIV 207
Cdd:cd03301   171 AELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQ 210
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 2-216 2.00e-58

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 190.32  E-value: 2.00e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   2 IKIEIKKELhgsnGVMNLDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQD--EKEFLPVQKRK 78
Cdd:TIGR02142   1 LSARFSKRL----GDFSLDADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDeGEIVLNGRTLFDsrKGIFLPPEKRR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  79 IGFVFQDYALFPNMTVLENLFFVNKD---KELANHLLEITELW---ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMD 152
Cdd:TIGR02142  77 IGYVFQEARLFPHLSVRGNLRYGMKRarpSERRISFERVIELLgigHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMD 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 153 EPLSALDptmrIKLQDEIL----QLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:TIGR02142 157 EPLAALD----DPRKYEILpyleRLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVW 220
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 1-216 7.76e-58

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 184.81  E-value: 7.76e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEikkELH---GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNE-IWQDEKEfLPVQ 75
Cdd:COG1126     1 MIEIE---NLHksfGDLEVLK-GISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDsGTITVDGEdLTDSKKD-INKL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  76 KRKIGFVFQDYALFPNMTVLENLFF-------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRP 146
Cdd:COG1126    76 RRKVGMVFQQFNLFPHLTVLENVTLapikvkkMSKAeaEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEP 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 147 KLLLMDEPLSALDPTMRiklqDEILQLHKEF---ETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1126   156 KVMLFDEPTSALDPELV----GEVLDVMRDLakeGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFF 224
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 1-216 1.58e-57

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 184.41  E-value: 1.58e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIE-IKKElHGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNE-IWQ-DEKEFLPVQk 76
Cdd:COG1127     5 MIEVRnLTKS-FGDRVVLD-GVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDsGEILVDGQdITGlSEKELYELR- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  77 RKIGFVFQDYALFPNMTVLENLFF-------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPK 147
Cdd:COG1127    82 RRIGMLFQGGALFDSLTVFENVAFplrehtdLSEAeiRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPE 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933 148 LLLMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1127   162 ILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELL 230
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
12-215 1.42e-56

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 185.92  E-value: 1.42e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  12 GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFP 90
Cdd:PRK09452   25 DGKEVIS-NLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPdSGRIMLDGQDITH----VPAENRHVNTVFQSYALFP 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLENLFFVNKDKELANHllEITE----------LWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP 160
Cdd:PRK09452  100 HMTVFENVAFGLRMQKTPAA--EITPrvmealrmvqLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDY 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 161 TMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK09452  178 KLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREI 232
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
4-215 4.47e-56

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 184.13  E-value: 4.47e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   4 IEIKK--ELHGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLE-KAQGIIKVDNeiwQDEKEfLPVQKRKIG 80
Cdd:PRK10851    3 IEIANikKSFGRTQVLN-DISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEhQTSGHIRFHG---TDVSR-LHARDRKVG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  81 FVFQDYALFPNMTVLENLFF----------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKL 148
Cdd:PRK10851   78 FVFQHYALFRHMTVFDNIAFgltvlprrerPNAAaiKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQI 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 149 LLMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK10851  158 LLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQV 224
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 20-216 4.99e-56

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 188.19  E-value: 4.99e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNE-IWQDEKEFLPVQKRKIGFVFQD--YALFPNMTV- 94
Cdd:COG1123   283 DVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPtSGSILFDGKdLTKLSRRSLRELRRRVQMVFQDpySSLNPRMTVg 362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 ------LENLFFVNKD--KELANHLLEITEL-WELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIK 165
Cdd:COG1123   363 diiaepLRLHGLLSRAerRERVAELLERVGLpPDLADRYPHELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQ 442

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 166 LQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1123   443 ILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVF 493
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 20-220 1.20e-55

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 179.45  E-value: 1.20e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGlekaqgIIKVDN-EIWQDEKEF--LPVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:cd03299    17 NVSLEVERGDYFVILGPTGSGKSVLLETIAG------FIKPDSgKILLNGKDItnLPPEKRDISYVPQNYALFPHMTVYK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF-----VNKDKELANHLLEITELW---ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:cd03299    91 NIAYglkkrKVDKKEIERKVLEIAEMLgidHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLRE 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 169 EILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKTS 220
Cdd:cd03299   171 ELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPK 222
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 20-216 1.23e-55

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 179.42  E-value: 1.23e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEiwqDEKEFLPVQ-KRKIGFVFQDYALFPNMTVLEN 97
Cdd:cd03295    19 NLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLiEPTSGEIFIDGE---DIREQDPVElRRKIGYVIQQIGLFPHMTVEEN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFV--------NKDKELANHLLEITEL--WELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:cd03295    96 IALVpkllkwpkEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGALDPITRDQLQ 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1441214933 168 DEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:cd03295   176 EEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEIL 224
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 1-210 4.96e-55

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 177.31  E-value: 4.96e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIE-IKKELHGSNGVMNL--DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDN-EIWQDEKEFLPVQ 75
Cdd:cd03257     1 LLEVKnLSVSFPTGGGSVKAldDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKpTSGSIIFDGkDLLKLSRRLRKIR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  76 KRKIGFVFQDY--ALFPNMTV-------LENLFFVNKDKELANHLLEITELWELK----NRLPNSLSGGQKQRVSLCRAL 142
Cdd:cd03257    81 RKEIQMVFQDPmsSLNPRMTIgeqiaepLRIHGKLSKKEARKEAVLLLLVGVGLPeevlNRYPHELSGGQRQRVAIARAL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 143 MNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03257   161 ALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 20-212 7.36e-54

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 175.25  E-value: 7.36e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDN-EIWQDEKEFLPVQKRKIGFVFQDYALFPNMTVLEN 97
Cdd:COG3638    21 DVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPtSGEILVDGqDVTALRGRALRRLRRRIGMIFQQFNLVPRLSVLTN 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 --------------LF--FVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP- 160
Cdd:COG3638   101 vlagrlgrtstwrsLLglFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPk 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 161 ----TMRIklqdeILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTA 212
Cdd:COG3638   181 tarqVMDL-----LRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPP 231
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 33-215 2.56e-53

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 176.14  E-value: 2.56e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  33 LTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEiwqdEKEFLPVQKRKIGFVFQDYALFPNMTVLENLFFVNKD------- 104
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQpDSGSIMLDGE----DVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMrkvprae 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 105 -KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEFETTTIL 183
Cdd:TIGR01187  77 iKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFVF 156

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1441214933 184 VSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:TIGR01187 157 VTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEI 188
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
20-210 2.72e-53

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 172.93  E-value: 2.72e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNeiwQD----EKEFLPVQKRKIGFVFQDYALFPNMTV 94
Cdd:COG2884    20 DVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPtSGQVLVNG---QDlsrlKRREIPYLRRRIGVVFQDFRLLPDRTV 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENLFFV--------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRikl 166
Cdd:COG2884    97 YENVALPlrvtgksrKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLADEPTGNLDPETS--- 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1441214933 167 qDEILQLHKEF---ETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:COG2884   174 -WEIMELLEEInrrGTTVLIATHDLELVDRMPKRVLELEDGRLVRDE 219
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 3-217 3.27e-53

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 177.60  E-value: 3.27e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   3 KIEIKKELHGSNGVMnlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNE-IWQ-DEKEFLPVQKRKI 79
Cdd:COG4175    30 KDEILEKTGQTVGVN--DASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLiEPTAGEVLIDGEdITKlSKKELRELRRKKM 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  80 GFVFQDYALFPNMTVLENLFF------VNKD--KELANHLLEITEL--WElkNRLPNSLSGGQKQRVSLCRALMNRPKLL 149
Cdd:COG4175   108 SMVFQHFALLPHRTVLENVAFgleiqgVPKAerRERAREALELVGLagWE--DSYPDELSGGMQQRVGLARALATDPDIL 185

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 150 LMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLL 217
Cdd:COG4175   186 LMDEAFSALDPLIRREMQDELLELQAKLKKTIVFITHDLDEALRLGDRIAIMKDGRIVQIGTPEEILT 253
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 4-206 4.11e-53

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 171.94  E-value: 4.11e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   4 IEIKKeLH---GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDEKEFLPVQKRKI 79
Cdd:cd03262     1 IEIKN-LHksfGDFHVLK-GIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDsGTIIIDGLKLTDDKKNINELRQKV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  80 GFVFQDYALFPNMTVLENLFF-------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLL 150
Cdd:cd03262    79 GMVFQQFNLFPHLTVLENITLapikvkgMSKAeaEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVML 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 151 MDEPLSALDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:cd03262   159 FDEPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGRI 213
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 20-274 5.72e-53

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 176.58  E-value: 5.72e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNE--IWQDEKEFLPVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:TIGR01186  11 DADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLiEPTAGQIFIDGEniMKQSPVELREVRRKKIGMVFQQFALFPHMTILQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFV--------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:TIGR01186  91 NTSLGpellgwpeQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSALDPLIRDSMQD 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 169 EILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKTSGSAKFSFEGKlLDIIKV-DVIYVAIIAi 247
Cdd:TIGR01186 171 ELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIGK-VDLSQVfDAERIAQRM- 248

                         250       260
                  ....*....|....*....|....*..
gi 1441214933 248 GQQLVEVTISSNEAKELRVGQDVRVST 274
Cdd:TIGR01186 249 NTGPITKTADKGPRSALQLMRDERVDS 275
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 4-215 7.50e-53

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 172.37  E-value: 7.50e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   4 IEIKK-ELHGSNGVMNL-DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKV-DNEIWQDEKEFLPVQKRKI 79
Cdd:cd03256     1 IEVENlSKTYPNGKKALkDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLvEPTSGSVLIdGTDINKLKGKALRQLRRQI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  80 GFVFQDYALFPNMTVLENL----------------FFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALM 143
Cdd:cd03256    81 GMIFQQFNLIERLSVLENVlsgrlgrrstwrslfgLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALM 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 144 NRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:cd03256   161 QQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 12-211 3.95e-52

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 170.38  E-value: 3.95e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  12 GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQD--EKEFLPVQKRkIGFVFQDYAL 88
Cdd:cd03261    11 GGRTVLK-GVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDsGEVLIDGEDISGlsEAELYRLRRR-MGMLFQSGAL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  89 FPNMTVLENL-FFVNKDKELANHllEITELWELK----------NRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:cd03261    89 FDSLTVFENVaFPLREHTRLSEE--EIREIVLEKleavglrgaeDLYPAELSGGMKKRVALARALALDPELLLYDEPTAG 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 158 LDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:cd03261   167 LDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGT 220
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 20-215 3.93e-51

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 167.36  E-value: 3.93e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQDEKEFLPVQ------KRKIGFVFQDYALFPnMT 93
Cdd:cd03260    18 DISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPGAPDEGEVLLDGKDIYDLDvdvlelRRRVGMVFQKPNPFP-GS 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENLFFVNKD---------KELANHLLEITELW-ELKNRL-PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTM 162
Cdd:cd03260    97 IYDNVAYGLRLhgiklkeelDERVEEALRKAALWdEVKDRLhALGLSGGQQQRLCLARALANEPEVLLLDEPTSALDPIS 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 163 RIKLQDEILQLHKefETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:cd03260   177 TAKIEELIAELKK--EYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
12-213 8.92e-51

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 170.29  E-value: 8.92e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  12 GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIWQDEKeflpVQKRKIGFVFQDYALFP 90
Cdd:PRK11432   17 GSNTVID-NLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKpTEGQIFIDGEDVTHRS----IQQRDICMVFQSYALFP 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLENLFF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTM 162
Cdd:PRK11432   92 HMSLGENVGYglkmlgVPKEerKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANL 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 163 RIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAK 213
Cdd:PRK11432  172 RRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQ 222
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 20-216 1.32e-50

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 166.90  E-value: 1.32e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEI--WQDEKEFlpvqKRKIGFVFQDY--ALFPNMTV 94
Cdd:COG1124    23 DVSLEVAPGESFGLVGESGSGKSTLLRALAGLERpWSGEVTFDGRPvtRRRRKAF----RRRVQMVFQDPyaSLHPRHTV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 -------LENLFFVNKDKELANhLLEITEL-WELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMrikl 166
Cdd:COG1124    99 drilaepLRIHGLPDREERIAE-LLEQVGLpPSFLDRYPHQLSGGQRQRVAIARALILEPELLLLDEPTSALDVSV---- 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 167 QDEIL----QLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1124   174 QAEILnllkDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLL 227
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
20-215 1.60e-50

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 169.49  E-value: 1.60e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEiwqdEKEFLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:NF040840   18 DISLEVKEGEYFIILGPSGAGKTVLLELIAGIwPPDSGKIYLDGK----DITNLPPEKRGIAYVYQNYMLFPHKTVFENI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFVNK-----DKELANHLLEITELW---ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:NF040840   94 AFGLKlrkvpKEEIERKVKEIMELLgisHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDELIREM 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:NF040840  174 KRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREV 218
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 20-216 2.78e-50

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 165.99  E-value: 2.78e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDN-EIWQ-DEKEFLpvqkRKIGFVFQDYALFPNMTVLE 96
Cdd:COG1120    19 DVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSsGEVLLDGrDLASlSRRELA----RRIAYVPQEPPAPFGLTVRE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 ----------NLFFVN--KDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:COG1120    95 lvalgryphlGLFGRPsaEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLLDEPTSHLDLAHQL 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 165 KLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1120   175 EVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVL 226
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 20-205 2.09e-49

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 162.64  E-value: 2.09e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNeiwQDEKEFLPVQKRK-IGFVFQ--DYALFpNMTVL 95
Cdd:cd03225    19 DISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTsGEVLVDG---KDLTKLSLKELRRkVGLVFQnpDDQFF-GPTVE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLFF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:cd03225    95 EEVAFglenlgLPEEeiEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELL 174

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1441214933 168 DEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGK 205
Cdd:cd03225   175 ELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
20-206 4.14e-49

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 166.36  E-value: 4.14e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIWQDekefLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:PRK11000   21 DINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDiTSGDLFIGEKRMND----VPPAERGVGMVFQSYALYPHLSVAENM 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:PRK11000   97 SFglklagAKKEeiNQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEI 176

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:PRK11000  177 SRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRV 212
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 20-206 5.29e-49

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 160.26  E-value: 5.29e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNE-IWQDEKEFlpvqKRKIGFVFQDYALFPNMTVLEN 97
Cdd:cd03230    18 DISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDsGEIKVLGKdIKKEPEEV----KRRIGYLPEEPSLYENLTVREN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LffvnkdkelanhlleitelwelknrlpnSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEf 177
Cdd:cd03230    94 L----------------------------KLSGGMKQRLALAQALLHDPELLILDEPTSGLDPESRREFWELLRELKKE- 144

                         170       180
                  ....*....|....*....|....*....
gi 1441214933 178 ETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:cd03230   145 GKTILLSSHILEEAERLCDRVAILNNGRI 173
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
1-215 1.75e-48

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 164.28  E-value: 1.75e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEIKKELhgsnGVMNLDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQD--EKEFLPVQKR 77
Cdd:PRK11144    1 MLELNFKQQL----GDLCLTVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQkGRIVLNGRVLFDaeKGICLPPEKR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  78 KIGFVFQDYALFPNMTVLENLFF--VNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPL 155
Cdd:PRK11144   77 RIGYVFQDARLFPHYKVRGNLRYgmAKSMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPL 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 156 SALD-PTMRiklqdEIL----QLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK11144  157 ASLDlPRKR-----ELLpyleRLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEV 216
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
1-226 3.36e-48

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 159.92  E-value: 3.36e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEikkELHGSNGVMNLDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNeiwQDEKEfLPVQKRKI 79
Cdd:COG3840     1 MLRLD---DLTYRYGDFPLRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPpDSGRILWNG---QDLTA-LPPAERPV 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  80 GFVFQDYALFPNMTVLENLFF--------VNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRAL-MNRPkLLL 150
Cdd:COG3840    74 SMLFQENNLFPHLTVAQNIGLglrpglklTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLvRKRP-ILL 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 151 MDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAkSVLLKTSGSAKFS 226
Cdd:COG3840   153 LDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPT-AALLDGEPPPALA 227
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 20-216 7.11e-48

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 159.48  E-value: 7.11e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIwqdekefLPVQKRKIGFVFQDYAL---FPnMTVL 95
Cdd:COG1121    24 DVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPpTSGTVRLFGKP-------PRRARRRIGYVPQRAEVdwdFP-ITVR 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 E----------NLF--FVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:COG1121    96 DvvlmgrygrrGLFrrPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATE 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 164 IKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLkDGKIVDDGTAKSVL 216
Cdd:COG1121   176 EALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLL-NRGLVAHGPPEEVL 226
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 1-215 2.70e-47

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 158.23  E-value: 2.70e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEIKKELHGSNGVMNLDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDN-EIWQDEKEFLPVQKRK 78
Cdd:TIGR02315   1 MLEVENLSKVYPNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLvEPSSGSILLEGtDITKLRGKKLRKLRRR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  79 IGFVFQDYALFPNMTVLENL----------------FFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRAL 142
Cdd:TIGR02315  81 IGMIFQHYNLIERLTVLENVlhgrlgykptwrsllgRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARAL 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 143 MNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:TIGR02315 161 AQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSEL 233
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
20-206 4.08e-47

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 156.51  E-value: 4.08e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIWQDekefLPVQK--RKIGFVFQDYALFPNmTVLE 96
Cdd:COG4619    18 PVSLTLEAGECVAITGPSGSGKSTLLRALADLDPpTSGEIYLDGKPLSA----MPPPEwrRQVAYVPQEPALWGG-TVRD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFVNK------DKELANHLLE---ITElwELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:COG4619    93 NLPFPFQlrerkfDRERALELLErlgLPP--DILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPTSALDPENTRRVE 170

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1441214933 168 DEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:COG4619   171 ELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 20-216 1.21e-46

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 165.78  E-value: 1.21e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDN-EIWQDEKEFLpvqKRKIGFVFQDYALFpNMTVLEN 97
Cdd:COG2274   493 NISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTsGRILIDGiDLRQIDPASL---RRQIGVVLQDVFLF-SGTIREN 568

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNK--DKELANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:COG2274   569 ITLGDPdaTDEEIIEAARLAGLHDFIEALPMgydtvvgeggsNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEA 648

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 165 KLQDEILQLHKefETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG2274   649 IILENLRRLLK--GRTVIIIAHRLSTI-RLADRIIVLDKGRIVEDGTHEELL 697
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 1-218 1.84e-46

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 155.82  E-value: 1.84e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIE-IKKELHGSNGVMNL--DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIWQDEKEF-LPVQ 75
Cdd:cd03258     1 MIELKnVSKVFGDTGGKVTAlkDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERpTSGSVLVDGTDLTLLSGKeLRKA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  76 KRKIGFVFQDYALFPNMTVLEN------LFFVNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPK 147
Cdd:cd03258    81 RRRIGMIFQHFNLLSSRTVFENvalpleIAGVPKAeiEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPK 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 148 LLLMDEPLSALDPtmriKLQDEILQL----HKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLK 218
Cdd:cd03258   161 VLLCDEATSALDP----ETTQSILALlrdiNRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFAN 231
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 20-212 3.60e-46

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 154.90  E-value: 3.60e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNE-IWQ-DEKEFLPVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:COG4181    30 GISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPtSGTVRLAGQdLFAlDEDARARLRARHVGFVFQSFQLLPTLTALE 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 N------LFFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:COG4181   110 NvmlpleLAGRRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLL 189

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1441214933 171 LQLHKEFETTTILVSHDPsEIYKLSNRVIVLKDGKIVDDGTA 212
Cdd:COG4181   190 FELNRERGTTLVLVTHDP-ALAARCDRVLRLRAGRLVEDTAA 230
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
1-218 4.71e-46

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 157.55  E-value: 4.71e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIE-IKKELHGSNG-VMNL-DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDN-EIWQ-DEKEfLPV 74
Cdd:COG1135     1 MIELEnLSKTFPTKGGpVTALdDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPtSGSVLVDGvDLTAlSERE-LRA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  75 QKRKIGFVFQDYALFPNMTVLENLFF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRP 146
Cdd:COG1135    80 ARRKIGMIFQHFNLLSSRTVAENVALpleiagVPKAeiRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNP 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 147 KLLLMDEPLSALDP--TmriklqDEILQL----HKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLK 218
Cdd:COG1135   160 KVLLCDEATSALDPetT------RSILDLlkdiNRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFAN 231
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
20-231 5.32e-46

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 158.46  E-value: 5.32e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNeiwQDEKEFLPVQkRKIGFVFQDYALFPNMTVLENL 98
Cdd:PRK11607   37 DVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQpTAGQIMLDG---VDLSHVPPYQ-RPINMMFQSYALFPHMTVEQNI 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFVNKDKELA--------NHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:PRK11607  113 AFGLKQDKLPkaeiasrvNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEV 192

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLL--KTSGSAKF-----SFEGKL 231
Cdd:PRK11607  193 VDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEhpTTRYSAEFigsvnVFEGVL 260
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 20-216 1.52e-45

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 154.53  E-value: 1.52e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNE-IWQDEKEFLPVQKRKIGFVFQ--DYALFPNmTVL 95
Cdd:TIGR04521  23 DVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTsGTVTIDGRdITAKKKKKLKDLRKKVGLVFQfpEHQLFEE-TVY 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLFF------VNKD--KELANHLLEITELWE-LKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKL 166
Cdd:TIGR04521 102 KDIAFgpknlgLSEEeaEERVKEALELVGLDEeYLERSPFELSGGQMRRVAIAGVLAMEPEVLILDEPTAGLDPKGRKEI 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1441214933 167 QDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:TIGR04521 182 LDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVF 231
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 20-216 1.86e-45

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 160.07  E-value: 1.86e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGiiKVDNEIWQDEKE--FLPVQKR--KIGFVFQD--YALFPnMT 93
Cdd:COG1123    24 GVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGG--RISGEVLLDGRDllELSEALRgrRIGMVFQDpmTQLNP-VT 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENLFFV--NKD------KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIK 165
Cdd:COG1123   101 VGDQIAEAleNLGlsraeaRARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALDVTTQAE 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 166 LQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1123   181 ILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEIL 231
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 1-236 3.35e-45

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 152.70  E-value: 3.35e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEikkELH---GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEiwqDEKEFLPVQK 76
Cdd:COG4555     1 MIEVE---NLSkkyGKVPALK-DVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDsGSILIDGE---DVRKEPREAR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  77 RKIGFVFQDYALFPNMTVLENL-FF-------VNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKL 148
Cdd:COG4555    74 RQIGVLPDERGLYDRLTVRENIrYFaelyglfDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKV 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 149 LLMDEPLSALDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKTSGSakfSFE 228
Cdd:COG4555   154 LLLDEPTNGLDVMARRLLREILRALKKE-GKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEE---NLE 229


                  ....*...
gi 1441214933 229 GKLLDIIK 236
Cdd:COG4555   230 DAFVALIG 237
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 12-233 4.55e-45

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 152.91  E-value: 4.55e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  12 GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDEKEflpvqkrKIGFVFQDYALFP 90
Cdd:PRK11247   23 GERTVLN-QLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPsAGELLAGTAPLAEARE-------DTRLMFQDARLLP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLEN--LFFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:PRK11247   95 WKKVIDNvgLGLKGQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQD 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 169 EILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKTSGSAKFS-FEGKLLD 233
Cdd:PRK11247  175 LIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVDLPRPRRRGSARLAeLEAEVLQ 240
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-211 5.96e-44

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 152.69  E-value: 5.96e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEI---KKELHGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIWQDEKeflPVQk 76
Cdd:PRK11650    1 MAGLKLqavRKSYDGKTQVIK-GIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERiTSGEIWIGGRVVNELE---PAD- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  77 RKIGFVFQDYALFPNMTVLENLFFVNKDKELANHLLE--------ITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKL 148
Cdd:PRK11650   76 RDIAMVFQNYALYPHMSVRENMAYGLKIRGMPKAEIEervaeaarILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAV 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 149 LLMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:PRK11650  156 FLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGT 218
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 13-210 1.51e-43

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 147.64  E-value: 1.51e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  13 SNGVMNLDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEiwqdEKEFLPVQKRKIGFVFQDYALFPN 91
Cdd:cd03298     9 SYGEQPMHFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQsGRVLINGV----DVTAAPPADRPVSMLFQENNLFAH 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 MTVLEN--------LFFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:cd03298    85 LTVEQNvglglspgLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALR 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1441214933 164 IKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03298   165 AEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 20-205 3.06e-43

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 145.22  E-value: 3.06e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDN-EIWQDEKEFLPvqkRKIGFVFQDYALFpNMTVLEN 97
Cdd:cd03228    20 DVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTsGEILIDGvDLRDLDLESLR---KNIAYVPQDPFLF-SGTIREN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LffvnkdkelanhlleitelwelknrlpnsLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKef 177
Cdd:cd03228    96 I-----------------------------LSGGQRQRIAIARALLRDPPILILDEATSALDPETEALILEALRALAK-- 144

                         170       180
                  ....*....|....*....|....*...
gi 1441214933 178 ETTTILVSHDPSEIyKLSNRVIVLKDGK 205
Cdd:cd03228   145 GKTVIVIAHRLSTI-RDADRIIVLDDGR 171
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 20-216 4.03e-43

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 149.43  E-value: 4.03e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGI----IKVDNE-IWQ-DEKEFLPVQKRKIGFVFQD-Y-ALFPN 91
Cdd:COG0444    23 GVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPGItsgeILFDGEdLLKlSEKELRKIRGREIQMIFQDpMtSLNPV 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 MTV-------LENLFFVNKD--KELANHLLE---ITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALD 159
Cdd:COG0444   103 MTVgdqiaepLRIHGGLSKAeaRERAIELLErvgLPDPERRLDRYPHELSGGMRQRVMIARALALEPKLLIADEPTTALD 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 160 PTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG0444   183 VTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 20-210 5.44e-43

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 144.89  E-value: 5.44e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNeiwQDEKEFLPVQK-RKIGFVFQdyalfpnmtvlen 97
Cdd:cd03214    17 DLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSsGEILLDG---KDLASLSPKELaRKIAYVPQ------------- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 lffvnkdkelanhLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEF 177
Cdd:cd03214    81 -------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQIELLELLRRLARER 147

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1441214933 178 ETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03214   148 GKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 20-201 8.84e-43

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 145.32  E-value: 8.84e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAqgiIKVDNEIWQDEKEF--LPVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:COG4136    19 PLSLTVAPGEILTLMGPSGSGKSTLLAAIAGtLSPA---FSASGEVLLNGRRLtaLPAEQRRIGILFQDDLLFPHLSVGE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF-----VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:COG4136    96 NLAFalpptIGRAqrRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAALRAQFREF 175

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1441214933 170 ILQLHKEFETTTILVSHDPSEIyKLSNRVIVL 201
Cdd:COG4136   176 VFEQIRQRGIPALLVTHDEEDA-PAAGRVLDL 206
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 20-205 9.68e-43

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 143.54  E-value: 9.68e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIWQdeKEFLPVQKRKIGFVFQdyalfpnmtvlenl 98
Cdd:cd00267    17 NVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKpTSGEILIDGKDIA--KLPLEELRRRIGYVPQ-------------- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 ffvnkdkelanhlleitelwelknrlpnsLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEfE 178
Cdd:cd00267    81 -----------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEE-G 130

                         170       180
                  ....*....|....*....|....*..
gi 1441214933 179 TTTILVSHDPSEIYKLSNRVIVLKDGK 205
Cdd:cd00267   131 RTVIIVTHDPELAELAADRVIVLKDGK 157
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 20-205 1.34e-41

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 142.39  E-value: 1.34e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDEKE-FLPVQKRKIGFVFQDYALFPNMTVLEN 97
Cdd:TIGR02673  20 DVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPsRGQVRIAGEDVNRLRGrQLPLLRRRIGVVFQDFRLLPDRTVYEN 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFV--------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTmrikLQDE 169
Cdd:TIGR02673 100 VALPlevrgkkeREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLADEPTGNLDPD----LSER 175

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1441214933 170 ILQLHKEFE---TTTILVSHDPSEIYKLSNRVIVLKDGK 205
Cdd:TIGR02673 176 ILDLLKRLNkrgTTVIVATHDLSLVDRVAHRVIILDDGR 214
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 20-216 1.58e-41

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 143.72  E-value: 1.58e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDEKEFLPVqKRKIGFVFQDyalfP-----NMT 93
Cdd:TIGR04520  20 NVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTsGKVTVDGLDTLDEENLWEI-RKKVGMVFQN----PdnqfvGAT 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 V-------LENLFFVNKD-KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIK 165
Cdd:TIGR04520  95 VeddvafgLENLGVPREEmRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILDEATSMLDPKGRKE 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 166 LQDEILQLHKEFETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:TIGR04520 175 VLETIRKLNKEEGITVISITHDMEEA-VLADRVIVMNKGKIVAEGTPREIF 224
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
12-216 3.22e-41

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 142.15  E-value: 3.22e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  12 GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDEKeflpVQKRKI----GFVFQDY 86
Cdd:PRK09493   12 GPTQVLH-NIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITsGDLIVDGLKVNDPK----VDERLIrqeaGMVFQQF 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  87 ALFPNMTVLENLFF-------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:PRK09493   87 YLFPHLTALENVMFgplrvrgASKEeaEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSA 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 158 LDPTMRiklqDEILQLHKEFET---TTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK09493  167 LDPELR----HEVLKVMQDLAEegmTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLI 224
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
20-207 1.49e-40

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 141.15  E-value: 1.49e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEiwqdekeflPVQ----KRkiGFVFQDYALFPNMTV 94
Cdd:COG4525    25 DVSLTIESGEFVVALGASGCGKTTLLNLIAGfLAPSSGEITLDGV---------PVTgpgaDR--GVVFQKDALLPWLNV 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENLFF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKL 166
Cdd:COG4525    94 LDNVAFglrlrgVPKAerRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGALDALTREQM 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1441214933 167 QDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKD--GKIV 207
Cdd:COG4525   174 QELLLDVWQRTGKGVFLITHSVEEALFLATRLVVMSPgpGRIV 216
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 20-205 1.83e-40

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 139.15  E-value: 1.83e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNE-IWQDEKEFlpvqKRKIGFVFQDYALFPNMTVLEN 97
Cdd:COG4133    20 GLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPsAGEVLWNGEpIRDAREDY----RRRLAYLGHADGLKPELTVREN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNK------DKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQdEIL 171
Cdd:COG4133    96 LRFWAAlyglraDREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLA-ELI 174

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1441214933 172 QLHKEFETTTILVSHDPSEIykLSNRVIVLKDGK 205
Cdd:COG4133   175 AAHLARGGAVLLTTHQPLEL--AAARVLDLGDFK 206
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
12-212 3.85e-40

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 139.76  E-value: 3.85e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  12 GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQ-----DEKEFLPVqKRKIGFVFQD 85
Cdd:COG4161    13 GSHQALF-DINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDsGQLNIAGHQFDfsqkpSEKAIRLL-RQKVGMVFQQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  86 YALFPNMTVLENL-------FFVNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:COG4161    91 YNLWPHLTVMENLieapckvLGLSKEqaREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTA 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 157 ALDPTMRIKLQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTA 212
Cdd:COG4161   171 ALDPEITAQVVEIIREL-SQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDA 225
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 11-212 5.59e-40

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 138.99  E-value: 5.59e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  11 HGSNGVMnLDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQ-----DEKEFLPVqKRKIGFVFQ 84
Cdd:PRK11124   12 YGAHQAL-FDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRsGTLNIAGNHFDfsktpSDKAIREL-RRNVGMVFQ 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  85 DYALFPNMTVLENL-------FFVNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPL 155
Cdd:PRK11124   90 QYNLWPHLTVQQNLieapcrvLGLSKDqaLARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPT 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 156 SALDPTMRIKLQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTA 212
Cdd:PRK11124  170 AALDPEITAQIVSIIREL-AETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDA 225
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 1-216 6.70e-40

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 139.11  E-value: 6.70e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEIK---KELHGsNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVdNEIWQDEKEFLPVQK 76
Cdd:PRK11264    1 MSAIEVKnlvKKFHG-QTVLH-GIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEaGTIRV-GDITIDTARSLSQQK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  77 RKI-------GFVFQDYALFPNMTVLENLF----FVNKDK-----ELANHLLEITELWELKNRLPNSLSGGQKQRVSLCR 140
Cdd:PRK11264   78 GLIrqlrqhvGFVFQNFNLFPHRTVLENIIegpvIVKGEPkeeatARARELLAKVGLAGKETSYPRRLSGGQQQRVAIAR 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 141 ALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK11264  158 ALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQE-KRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALF 232
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 20-206 1.18e-39

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 137.28  E-value: 1.18e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDneiwqdeKEFLPVQKRKIGFVFQDYAL---FPnMTVL 95
Cdd:cd03235    17 DVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKpTSGSIRVF-------GKPLEKERKRIGYVPQRRSIdrdFP-ISVR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 EnlfFV---------------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP 160
Cdd:cd03235    89 D---VVlmglyghkglfrrlsKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDP 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1441214933 161 TMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:cd03235   166 KTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLLNRTVV 210
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 20-204 1.71e-39

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 137.60  E-value: 1.71e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK--AQGIIKVDNEIWQdekeflPVQKRKIgfVFQDYALFPNMTVLEN 97
Cdd:TIGR01184   3 GVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQptSGGVILEGKQITE------PGPDRMV--VFQNYSLLPWLTVREN 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFF----VNKD------KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:TIGR01184  75 IALavdrVLPDlskserRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQ 154

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1441214933 168 DEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDG 204
Cdd:TIGR01184 155 EELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 20-207 3.91e-39

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 135.85  E-value: 3.91e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEiWQDEKEFLpvqkRKIGFVFQD--YALFPNmTVLE 96
Cdd:cd03226    18 DLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKeSSGSILLNGK-PIKAKERR----KSIGYVMQDvdYQLFTD-SVRE 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFVNKD----KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQ 172
Cdd:cd03226    92 ELLLGLKEldagNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNMERVGELIRE 171

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1441214933 173 LHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIV 207
Cdd:cd03226   172 LAAQ-GKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
heterocyst_DevA TIGR02982
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...
 20-207 1.01e-38

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.


Pssm-ID: 274374 [Multi-domain]  Cd Length: 220  Bit Score: 135.15  E-value: 1.01e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKV-DNEIWQDEKEFLPVQKRKIGFVFQDYALFPNMTVLEN 97
Cdd:TIGR02982  23 DINLEINPGEIVILTGPSGSGKTTLLTLIGGLRSVQeGSLKVlGQELHGASKKQLVQLRRRIGYIFQAHNLLGFLTARQN 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 L---------FFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP-TMRIKLq 167
Cdd:TIGR02982 103 VqmalelqpnLSYQEARERARAMLEAVGLGDHLNYYPHNLSGGQKQRVAIARALVHHPKLVLADEPTAALDSkSGRDVV- 181

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1441214933 168 dEILQ-LHKEFETTTILVSHDPsEIYKLSNRVIVLKDGKIV 207
Cdd:TIGR02982 182 -ELMQkLAKEQGCTILMVTHDN-RILDVADRILQMEDGKLL 220
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 20-216 1.20e-38

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 134.87  E-value: 1.20e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqDEKEFLPVQ--KRKIGFVFQDYALFPNMTVLE 96
Cdd:cd03224    18 GVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPrSGSIRFDGR---DITGLPPHEraRAGIGYVPEGRRIFPELTVEE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NL---FFVNKDKELANHLLEITELW----ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:cd03224    95 NLllgAYARRRAKRKARLERVYELFprlkERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIVEEIFEA 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1441214933 170 ILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:cd03224   175 IRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELL 220
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 20-156 1.89e-38

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 132.39  E-value: 1.89e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDN-EIWQDEKEFLpvqKRKIGFVFQDYALFPNMTVLEN 97
Cdd:pfam00005   3 NVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSpTEGTILLDGqDLTDDERKSL---RKEIGYVFQDPQLFPRLTVREN 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1441214933  98 LFFVNKDKEL--------ANHLLEITELWELKNRL----PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:pfam00005  80 LRLGLLLKGLskrekdarAEEALEKLGLGDLADRPvgerPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 20-216 3.74e-38

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 134.44  E-value: 3.74e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGlekaqgiikvdnEIWQDEKEFLPVQ------------KRKIGFV---FQ 84
Cdd:COG1119    21 DISWTVKPGEHWAILGPNGAGKSTLLSLITG------------DLPPTYGNDVRLFgerrggedvwelRKRIGLVspaLQ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  85 DYaLFPNMTVLENL---FF---------VNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMD 152
Cdd:COG1119    89 LR-FPRDETVLDVVlsgFFdsiglyrepTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPELLILD 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 153 EPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1119   168 EPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVL 231
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 20-221 4.41e-38

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 140.66  E-value: 4.41e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNeiwQDEKEFLPVQKRK-IGFVFQDYALFPnMTVLEN 97
Cdd:COG4988   355 GLSLTIPPGERVALVGPSGAGKSTLLNLLLGfLPPYSGSILING---VDLSDLDPASWRRqIAWVPQNPYLFA-GTIREN 430

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNK---DKELAnHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:COG4988   431 LRLGRPdasDEELE-AALEAAGLDEFVAALPDgldtplgeggrGLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETE 509

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 164 IKLQDEILQLHKefETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGTAKSvLLKTSG 221
Cdd:COG4988   510 AEILQALRRLAK--GRTVILITHRLALL-AQADRILVLDDGRIVEQGTHEE-LLAKNG 563
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 20-216 4.87e-38

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 133.72  E-value: 4.87e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNE-IWQdekefLPVQKRK---IGFVFQDYALFPNMTV 94
Cdd:cd03219    18 DVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPtSGSVLFDGEdITG-----LPPHEIArlgIGRTFQIPRLFPELTV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENL---------------FFVNKDKEL---ANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:cd03219    93 LENVmvaaqartgsglllaRARREEREArerAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAA 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 157 ALDPTMRIKLQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:cd03219   173 GLNPEETEELAELIREL-RERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVR 231
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
20-221 6.16e-38

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 140.69  E-value: 6.16e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNeiwQDEKEFLPVQKRK-IGFVFQDYALFpNMTVLEN 97
Cdd:COG1132   358 DISLTIPPGETVALVGPSGSGKSTLVNLLLRFyDPTSGRILIDG---VDIRDLTLESLRRqIGVVPQDTFLF-SGTIREN 433

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNKD--KELANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:COG1132   434 IRYGRPDatDEEVEEAAKAAQAHEFIEALPDgydtvvgergvNLSGGQRQRIAIARALLKDPPILILDEATSALDTETEA 513

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 165 KLQDEILQLHKefETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGTAKSvLLKTSG 221
Cdd:COG1132   514 LIQEALERLMK--GRTTIVIAHRLSTI-RNADRILVLDDGRIVEQGTHEE-LLARGG 566
cbiO PRK13637
energy-coupling factor transporter ATPase;
20-215 2.61e-37

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 133.63  E-value: 2.61e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDEKEFLPVQKRKIGFVFQ--DYALFPNmTVLE 96
Cdd:PRK13637   25 NVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPtSGKIIIDGVDITDKKVKLSDIRKKVGLVFQypEYQLFEE-TIEK 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFVNK-----DKELANHLLEITELW-----ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKL 166
Cdd:PRK13637  104 DIAFGPInlglsEEEIENRVKRAMNIVgldyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEI 183

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1441214933 167 QDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK13637  184 LNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREV 232
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 20-211 4.32e-37

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 131.09  E-value: 4.32e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKV-DNEIWQDEKEflpvQKRKIGFVFQDYALFPNMTVLEN 97
Cdd:cd03263    20 DLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTsGTAYInGYSIRTDRKA----ARQSLGYCPQFDALFDELTVREH 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFF--------VNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:cd03263    96 LRFyarlkglpKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDL 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1441214933 170 ILQLHKefETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:cd03263   176 ILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGS 215
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 20-216 2.59e-36

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 130.16  E-value: 2.59e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GiikvdnEIWQDEKEF--LPVQKR-KIGFV--FQDYALFPNMT 93
Cdd:COG0411    22 DVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTsG------RILFDGRDItgLPPHRIaRLGIArtFQNPRLFPELT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENL--------------------FFVNKDKEL---ANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLL 150
Cdd:COG0411    96 VLENVlvaaharlgrgllaallrlpRARREEREArerAEELLERVGLADRADEPAGNLSYGQQRRLEIARALATEPKLLL 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 151 MDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG0411   176 LDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEVR 241
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 20-216 2.16e-35

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 127.02  E-value: 2.16e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdekeflPVQKRK--------IGFVFQDYALFP 90
Cdd:COG0410    21 GVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPrSGSIRFDGE---------DITGLPphriarlgIGYVPEGRRIFP 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLENL---FFVNKDKELANHLLE-ITELW----ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTM 162
Cdd:COG0410    92 SLTVEENLllgAYARRDRAEVRADLErVYELFprlkERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLI 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 163 RIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG0410   172 VEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELL 224
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 20-216 2.42e-35

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 132.89  E-value: 2.42e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQ--DEKEFLPVqKRKIGFVFQD-YA-LFPNMTVL 95
Cdd:COG4172   304 GVSLTLRRGETLGLVGESGSGKSTLGLALLRLIPSEGEIRFDGQDLDglSRRALRPL-RRRMQVVFQDpFGsLSPRMTVG 382

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 E------NLFFVNKDK----ELANHLLEITEL-WELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTmri 164
Cdd:COG4172   383 QiiaeglRVHGPGLSAaerrARVAEALEEVGLdPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVS--- 459

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 165 kLQDEILQL----HKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG4172   460 -VQAQILDLlrdlQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVF 514
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 20-210 2.66e-35

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 126.16  E-value: 2.66e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDN-EIWQdekefLPVQ--KRKIGFVFQDYALFpNMTVL 95
Cdd:cd03245    22 NVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTsGSVLLDGtDIRQ-----LDPAdlRRNIGYVPQDVTLF-YGTLR 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLFFVN---KDKELANhLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPT 161
Cdd:cd03245    96 DNITLGAplaDDERILR-AAELAGVTDFVNKHPNgldlqigergrGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMN 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1441214933 162 MRIKLQDEILQLHKefETTTILVSHDPSeIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03245   175 SEERLKERLRQLLG--DKTLIIITHRPS-LLDLVDRIIVMDSGRIVADG 220
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 14-206 3.18e-35

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 125.98  E-value: 3.18e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  14 NGVMNL-DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDN-EIWQDEKEFLPVQKRKIGFVFQDYALFP 90
Cdd:cd03292    12 NGTAALdGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELpTSGTIRVNGqDVSDLRGRAIPYLRRKIGVVFQDFRLLP 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLENLFFV-----NKDKELANHLLEITELWELKNR---LPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTM 162
Cdd:cd03292    92 DRNVYENVAFAlevtgVPPREIRKRVPAALELVGLSHKhraLPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDT 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1441214933 163 riklQDEILQLHKEFE---TTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:cd03292   172 ----TWEIMNLLKKINkagTTVVVATHAKELVDTTRHRVIALERGKL 214
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 22-206 5.64e-35

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 125.36  E-value: 5.64e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  22 NLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNeiwQDEKEFLPVQkRKIGFVFQDYALFPNMTVLEN--- 97
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGfIEPASGSIKVND---QSHTGLAPYQ-RPVSMLFQENNLFAHLTVRQNigl 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 -----LFFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQ 172
Cdd:TIGR01277  94 glhpgLKLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQ 173

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1441214933 173 LHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:TIGR01277 174 LCSERQRTLLMVTHHLSDARAIASQIAVVSQGKI 207
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
2-216 7.85e-35

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 126.07  E-value: 7.85e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   2 IKIEIKkELH---GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEI--WQDEK--EFLP 73
Cdd:COG4598     7 PALEVR-DLHksfGDLEVLK-GVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPdSGEIRVGGEEirLKPDRdgELVP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  74 VQKR-------KIGFVFQDYALFPNMTVLENLFF-------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVS 137
Cdd:COG4598    85 ADRRqlqrirtRLGMVFQSFNLWSHMTVLENVIEapvhvlgRPKAeaIERAEALLAKVGLADKRDAYPAHLSGGQQQRAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 138 LCRALMNRPKLLLMDEPLSALDPtmriKLQDEIL----QLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAK 213
Cdd:COG4598   165 IARALAMEPEVMLFDEPTSALDP----ELVGEVLkvmrDLAEE-GRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPA 239


                  ...
gi 1441214933 214 SVL 216
Cdd:COG4598   240 EVF 242
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 20-215 1.11e-34

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 125.92  E-value: 1.11e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQDEKEFL-----PVQ-KRKIGFVFQDYALFPnMT 93
Cdd:COG1117    29 DINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLIPGARVEGEILLDGEDIYdpdvdVVElRRRVGMVFQKPNPFP-KS 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENLFF------VNKDKELAnhllEITE-------LW-ELKNRL---PNSLSGGQKQRvsLC--RALMNRPKLLLMDEP 154
Cdd:COG1117   108 IYDNVAYglrlhgIKSKSELD----EIVEeslrkaaLWdEVKDRLkksALGLSGGQQQR--LCiaRALAVEPEVLLMDEP 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 155 LSALDP--TMRIklQDEILQLHKEFetTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:COG1117   182 TSALDPisTAKI--EELILELKKDY--TIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQI 240
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
20-216 1.23e-34

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 129.00  E-value: 1.23e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDN-EIWQ-DEKEFLPVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:PRK10070   46 DASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLiEPTRGQVLIDGvDIAKiSDAELREVRRKKIAMVFQSFALMPHMTVLD 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF--------VNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:PRK10070  126 NTAFgmelaginAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQD 205

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1441214933 169 EILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK10070  206 ELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIL 253
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 20-210 1.58e-34

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 123.87  E-value: 1.58e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDEKEFLpvqkRKIGFVFQDYALFPNMTVLENL 98
Cdd:cd03268    18 DISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPdSGEITFDGKSYQKNIEAL----RRIGALIEAPGFYPNLTARENL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFVNK----DKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPtMRIKLQDEILQLH 174
Cdd:cd03268    94 RLLARllgiRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDP-DGIKELRELILSL 172

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1441214933 175 KEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03268   173 RDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 20-221 2.08e-34

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 130.66  E-value: 2.08e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNeiwQDEKEFLPVQKRK-IGFVFQDYALFpNMTVLEN 97
Cdd:COG4987   353 GLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQsGSITLGG---VDLRDLDEDDLRRrIAVVPQRPHLF-DTTLREN 428

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNK---DKELAnHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:COG4987   429 LRLARPdatDEELW-AALERVGLGDWLAALPDgldtwlgeggrRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATE 507

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 164 IKLQDEILQLHKefETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGTAKSvLLKTSG 221
Cdd:COG4987   508 QALLADLLEALA--GRTVLLITHRLAGL-ERMDRILVLEDGRIVEQGTHEE-LLAQNG 561
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 20-212 2.56e-34

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 123.63  E-value: 2.56e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQG--IIKVDNEIWQDEKEFlpvqKRKIGFVFQDYALFPNMTVLEN 97
Cdd:cd03265    18 GVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSgrATVAGHDVVREPREV----RRRIGIVFQDLSVDDELTGWEN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFV--------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:cd03265    94 LYIHarlygvpgAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEY 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1441214933 170 ILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTA 212
Cdd:cd03265   174 IEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTP 216
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 1-211 3.30e-34

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 126.45  E-value: 3.30e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIE-IKKELH-GSNGVMNL-DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDN-EIWQ-DEKEfLPV 74
Cdd:PRK11153    1 MIELKnISKVFPqGGRTIHALnNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERpTSGRVLVDGqDLTAlSEKE-LRK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  75 QKRKIGFVFQDYALFPNMTVLENLFF----VNKDKEL----ANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRP 146
Cdd:PRK11153   80 ARRQIGMIFQHFNLLSSRTVFDNVALplelAGTPKAEikarVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNP 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 147 KLLLMDEPLSALDP-TMRiklqdEILQLHK----EFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:PRK11153  160 KVLLCDEATSALDPaTTR-----SILELLKdinrELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGT 224
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
11-211 4.42e-34

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 124.41  E-value: 4.42e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  11 HGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKvdneiWQDE----------KEFlpvqKRKI 79
Cdd:PRK10419   22 HQHQTVLN-NVSLSLKSGETVALLGRSGCGKSTLARLLVGLESpSQGNVS-----WRGEplaklnraqrKAF----RRDI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  80 GFVFQDY--ALFPNMTV-------LENLFFVNKDKELAN--HLLEITEL-WELKNRLPNSLSGGQKQRVSLCRALMNRPK 147
Cdd:PRK10419   92 QMVFQDSisAVNPRKTVreiirepLRHLLSLDKAERLARasEMLRAVDLdDSVLDKRPPQLSGGQLQRVCLARALAVEPK 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 148 LLLMDEPLSALDptmrIKLQDEILQLHK----EFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:PRK10419  172 LLILDEAVSNLD----LVLQAGVIRLLKklqqQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQP 235
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 20-210 5.30e-34

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 122.69  E-value: 5.30e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIrSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNeiwQDEKEFLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:cd03264    18 GVSLTL-GPGMYGLLGPNGAGKTTLMRILATLTPPsSGTIRIDG---QDVLKQPQKLRRRIGYLPQEFGVYPNFTVREFL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFV--------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:cd03264    94 DYIawlkgipsKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLDPEERIRFRNLL 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1441214933 171 LQLHKefETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03264   174 SELGE--DRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 20-201 6.85e-34

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 122.34  E-value: 6.85e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK---AQGIIKVDNEIWQDEKEFLPVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:TIGR03608  16 DLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKfdsGQVYLNGQETPPLNSKKASKFRREKLGYLFQNFALIENETVEE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NL----FFVNKDK----ELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:TIGR03608  96 NLdlglKYKKLSKkekrEKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADEPTGSLDPKNRDEVLD 175

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1441214933 169 EILQLHKEfETTTILVSHDPsEIYKLSNRVIVL 201
Cdd:TIGR03608 176 LLLELNDE-GKTIIIVTHDP-EVAKQADRVIEL 206
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 1-216 7.00e-34

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 123.48  E-value: 7.00e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEIK--KELHGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQDEKEFLPVQ--- 75
Cdd:PRK14247    1 MNKIEIRdlKVSFGQVEVLD-GVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIELYPEARVSGEVYLDGQDIFKMDvie 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  76 -KRKIGFVFQDYALFPNMTVLENLFF-------VNKDKELANHL---LEITELW-ELKNRL---PNSLSGGQKQRVSLCR 140
Cdd:PRK14247   80 lRRRVQMVFQIPNPIPNLSIFENVALglklnrlVKSKKELQERVrwaLEKAQLWdEVKDRLdapAGKLSGGQQQRLCIAR 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 141 ALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEFetTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK14247  160 ALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDM--TIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVF 233
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 20-209 8.46e-34

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 123.66  E-value: 8.46e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLekaqgiIKVDN-EIWQDEKE--FLPVQKR--KIGFVFQDYAL--FPNM 92
Cdd:COG1101    24 GLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGS------LPPDSgSILIDGKDvtKLPEYKRakYIGRVFQDPMMgtAPSM 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  93 TVLENL-------------FFVNK-DKELANHLLEITELwELKNRLPN---SLSGGQKQRVSLCRALMNRPKLLLMDEPL 155
Cdd:COG1101    98 TIEENLalayrrgkrrglrRGLTKkRRELFRELLATLGL-GLENRLDTkvgLLSGGQRQALSLLMATLTKPKLLLLDEHT 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 156 SALDPtmriKLQDEILQLH----KEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDD 209
Cdd:COG1101   177 AALDP----KTAALVLELTekivEENNLTTLMVTHNMEQALDYGNRLIMMHEGRIILD 230
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 21-216 1.91e-33

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 127.61  E-value: 1.91e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVD-NEIWQDEKEFLPVQ----KRKIGFVFQDYALFPNMTV 94
Cdd:TIGR03269 303 VSLEVKEGEIFGIVGTSGAGKTTLSKIIAGvLEPTSGEVNVRvGDEWVDMTKPGPDGrgraKRYIGILHQEYDLYPHRTV 382

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENL---FFVNKDKELAN----HLLEITELWELK-----NRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTM 162
Cdd:TIGR03269 383 LDNLteaIGLELPDELARmkavITLKMVGFDEEKaeeilDKYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPIT 462

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 163 RIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:TIGR03269 463 KVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIV 516
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 11-216 5.41e-33

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 121.49  E-value: 5.41e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  11 HGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNE-------IWQDEKEFLPVqKRKIGFVF 83
Cdd:PRK14267   14 YGSNHVIK-GVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNEEARVEGEvrlfgrnIYSPDVDPIEV-RREVGMVF 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  84 QDYALFPNMTVLENLFFVNKDKELANHLLEITE----------LW-ELKNRL---PNSLSGGQKQRVSLCRALMNRPKLL 149
Cdd:PRK14267   92 QYPNPFPHLTIYDNVAIGVKLNGLVKSKKELDErvewalkkaaLWdEVKDRLndyPSNLSGGQRQRLVIARALAMKPKIL 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 150 LMDEPLSALDPTMRIKLQDEILQLHKEFetTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK14267  172 LMDEPTANIDPVGTAKIEELLFELKKEY--TIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVF 236
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 20-206 5.49e-33

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 118.86  E-value: 5.49e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNeiwQDEKEFLPVQKRK-IGFVFQDYALFPNmTVLEN 97
Cdd:cd03246    20 NVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRpTSGRVRLDG---ADISQWDPNELGDhVGYLPQDDELFSG-SIAEN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LffvnkdkelanhlleitelwelknrlpnsLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLhKEF 177
Cdd:cd03246    96 I-----------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIAAL-KAA 145

                         170       180
                  ....*....|....*....|....*....
gi 1441214933 178 ETTTILVSHDPSEIyKLSNRVIVLKDGKI 206
Cdd:cd03246   146 GATRIVIAHRPETL-ASADRILVLEDGRV 173
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 11-208 1.88e-32

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 120.30  E-value: 1.88e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  11 HGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNE-IWQDEKEFLPVQKRKIGFVFQDY-- 86
Cdd:TIGR02769  21 KQRAPVLT-NVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKpAQGTVSFRGQdLYQLDRKQRRAFRRDVQLVFQDSps 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  87 ALFPNMTV-------LENLFFVNKDKELAN--HLLEITELW-ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:TIGR02769 100 AVNPRMTVrqiigepLRHLTSLDESEQKARiaELLDMVGLRsEDADKLPRQLSGGQLQRINIARALAVKPKLIVLDEAVS 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 157 ALDptmrIKLQDEILQ----LHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVD 208
Cdd:TIGR02769 180 NLD----MVLQAVILEllrkLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVE 231
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
22-234 5.08e-32

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 118.15  E-value: 5.08e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  22 NLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNeiwQDEKEFLPVQkRKIGFVFQDYALFPNMTVLEN--- 97
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKSTLLNLIAGfLTPASGSLTLNG---QDHTTTPPSR-RPVSMLFQENNLFSHLTVAQNigl 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 -----LFFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIklqdEILQ 172
Cdd:PRK10771   95 glnpgLKLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQ----EMLT 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 173 LHKEF----ETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLlktSGSAKfsfEGKLLDI 234
Cdd:PRK10771  171 LVSQVcqerQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELL---SGKAS---ASALLGI 230
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 20-219 8.50e-32

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 118.97  E-value: 8.50e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEIWQ---DEKEFLPVQKrKIGFVFQ--DYALFPNmT 93
Cdd:PRK13634   25 DVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQpTSGTVTIGERVITagkKNKKLKPLRK-KVGIVFQfpEHQLFEE-T 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENLFF------VNKD--KELANHLLEITELWE-LKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:PRK13634  103 VEKDICFgpmnfgVSEEdaKQKAREMIELVGLPEeLLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRK 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 165 KLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKT 219
Cdd:PRK13634  183 EMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP 237
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 21-206 3.05e-31

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 116.03  E-value: 3.05e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQG--IIKVDNEIWQ-DEKEFLPVQKRKIGFVFQDYALFPNMTVLEN 97
Cdd:PRK10584   29 VELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSgeVSLVGQPLHQmDEEARAKLRAKHVGFVFQSFMLIPTLNALEN 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFV--------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:PRK10584  109 VELPallrgessRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADL 188

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1441214933 170 ILQLHKEFETTTILVSHDPsEIYKLSNRVIVLKDGKI 206
Cdd:PRK10584  189 LFSLNREHGTTLILVTHDL-QLAARCDRRLRLVNGQL 224
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
20-215 4.12e-31

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 120.89  E-value: 4.12e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdEKEFLPV---QKRKIGFVFQDYALFPNMTVL 95
Cdd:COG1129    22 GVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPdSGEILLDGE----PVRFRSPrdaQAAGIAIIHQELNLVPNLSVA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLF---------FVNKdKELANHLLEITELWELK---NRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:COG1129    98 ENIFlgreprrggLIDW-RAMRRRARELLARLGLDidpDTPVGDLSVAQQQLVEIARALSRDARVLILDEPTASLTEREV 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 164 IKLQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:COG1129   177 ERLFRIIRRL-KAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAEL 227
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 20-216 5.21e-31

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 121.51  E-value: 5.21e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDN-EIWQDEKEFLpvqKRKIGFVFQDYALFpNMTVLEN 97
Cdd:TIGR03375 483 NVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTeGSVLLDGvDIRQIDPADL---RRNIGYVPQDPRLF-YGTLRDN 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVN---KDKELANhLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPT-- 161
Cdd:TIGR03375 559 IALGApyaDDEEILR-AAELAGVTEFVRRHPDgldmqigergrSLSGGQRQAVALARALLRDPPILLLDEPTSAMDNRse 637

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 162 MRIK--LQDEILqlhkefETTTILVSHDPSeIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:TIGR03375 638 ERFKdrLKRWLA------GKTLVLVTHRTS-LLDLVDRIIVMDNGRIVADGPKDQVL 687
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 20-210 5.59e-31

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 114.19  E-value: 5.59e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL---EKAQGIIKVdNEIWQDEKEFlpvqKRKIGFVFQDYALFPNMTVLE 96
Cdd:cd03213    27 NVSGKAKPGELTAIMGPSGAGKSTLLNALAGRrtgLGVSGEVLI-NGRPLDKRSF----RKIIGYVPQDDILHPTLTVRE 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFVNKdkelanhlleitelweLKnrlpnSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKE 176
Cdd:cd03213   102 TLMFAAK----------------LR-----GLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADT 160

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1441214933 177 fETTTILVSHDPS-EIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03213   161 -GRTIICSIHQPSsEIFELFDKLLLLSQGRVIYFG 194
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 20-211 1.89e-30

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 116.34  E-value: 1.89e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEI-WQDEKEFLpvqkRKIGFVF-QDYALFPNMTVLE 96
Cdd:COG4586    40 DISFTIEPGEIVGFIGPNGAGKSTTIKMLTGiLVPTSGEVRVLGYVpFKRRKEFA----RRIGVVFgQRSQLWWDLPAID 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NlFFVNK------DKELANHLLEITELWELKNRL--P-NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:COG4586   116 S-FRLLKaiyripDAEYKKRLDELVELLDLGELLdtPvRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIR 194

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1441214933 168 DEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:COG4586   195 EFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGS 238
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 20-218 2.10e-30

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 113.86  E-value: 2.10e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDN-EIWQDEKEFLpvqKRKIGFVFQDYALFPNmTVLEN 97
Cdd:cd03254    21 DINFSIKPGETVAIVGPTGAGKTTLINLLMRFyDPQKGQILIDGiDIRDISRKSL---RSMIGVVLQDTFLFSG-TIMEN 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFF--VNKDKELANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:cd03254    97 IRLgrPNATDEEVIEAAKEAGAHDFIMKLPNgydtvlgenggNLSQGERQLLAIARAMLRDPKILILDEATSNIDTETEK 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 165 KLQDEILQLHKefETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGTAKSVLLK 218
Cdd:cd03254   177 LIQEALEKLMK--GRTSIIIAHRLSTI-KNADKILVLDDGKIIEEGTHDELLAK 227
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
 20-270 2.57e-30

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 115.57  E-value: 2.57e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK---AQGIIKVDNEIWQDEKeflpvQKRKIGFVFQDYALFPNMTVLE 96
Cdd:TIGR01188  11 GVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRptsGTARVAGYDVVREPRK-----VRRSIGIVPQYASVDEDLTGRE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:TIGR01188  86 NLEMmgrlygLPKDeaEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTRRAIWD 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 169 EILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSvlLKTSGSAKFsFEGKLLDIIKVDVIyvaiiaIG 248
Cdd:TIGR01188 166 YIRAL-KEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEE--LKRRLGKDT-LESRPRDIQSLKVE------VS 235

                         250       260
                  ....*....|....*....|..
gi 1441214933 249 QQLVEVTISSNEAKELRVGQDV 270
Cdd:TIGR01188 236 MLIAELGETGLGLLAVTVDSDR 257
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 21-211 2.62e-30

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 114.32  E-value: 2.62e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNEiwqdEKEFLPVQK--RKiGFV--FQDYALFPNMTVL 95
Cdd:PRK11300   24 VNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKpTGGTILLRGQ----HIEGLPGHQiaRM-GVVrtFQHVRLFREMTVI 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLF--------------------FVNKDKE---LANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMD 152
Cdd:PRK11300   99 ENLLvaqhqqlktglfsgllktpaFRRAESEaldRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLD 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933 153 EPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:PRK11300  179 EPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGT 237
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 20-217 2.83e-30

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 114.10  E-value: 2.83e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQDEKE-FLP----VQKRK-IGFVFQDYALFPnMT 93
Cdd:PRK14239   23 SVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNPEVTITGSIVYNGHNiYSPrtdtVDLRKeIGMVFQQPNPFP-MS 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENLFF---VN--KDKELANHLLEIT----ELW-ELKNRLPNS---LSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP 160
Cdd:PRK14239  102 IYENVVYglrLKgiKDKQVLDEAVEKSlkgaSIWdEVKDRLHDSalgLSGGQQQRVCIARVLATSPKIILLDEPTSALDP 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 161 TMRIKLQDEILQLHKEFetTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLL 217
Cdd:PRK14239  182 ISAGKIEETLLGLKDDY--TMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFM 236
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
20-204 5.28e-30

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 113.64  E-value: 5.28e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDekeflPVQKRkiGFVFQDYALFPNMTVLENL 98
Cdd:PRK11248   19 DINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQhGSITLDGKPVEG-----PGAER--GVVFQNEGLLPWRNVQDNV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF------VNKDK--ELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:PRK11248   92 AFglqlagVEKMQrlEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQMQTLL 171

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1441214933 171 LQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDG 204
Cdd:PRK11248  172 LKLWQETGKQVLLITHDIEEAVFMATELVLLSPG 205
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 20-207 6.21e-30

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 111.99  E-value: 6.21e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIWQDEKeflpvqKRKIGFVFQDYALFPNMTVLENL 98
Cdd:cd03269    18 DISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPdSGEVLFDGKPLDIAA------RNRIGYLPEERGLYPKMKVIDQL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFVNKDKEL--------ANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:cd03269    92 VYLAQLKGLkkeearrrIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVI 171

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1441214933 171 LQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIV 207
Cdd:cd03269   172 REL-ARAGKTVILSTHQMELVEELCDRVLLLNKGRAV 207
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 20-211 8.51e-30

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 112.32  E-value: 8.51e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNeiwQDEKEF-LPVQKRKIGFVFQDYALFpNMTVLEN 97
Cdd:cd03251    20 DISLDIPAGETVALVGPSGSGKSTLVNLIPRFyDVDSGRILIDG---HDVRDYtLASLRRQIGLVSQDVFLF-NDTVAEN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNKDKELAN--HLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:cd03251    96 IAYGRPGATREEveEAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAIARALLKDPPILILDEATSALDTESER 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1441214933 165 KLQDEILQLHKefETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGT 211
Cdd:cd03251   176 LVQAALERLMK--NRTTFVIAHRLSTI-ENADRIVVLEDGKIVERGT 219
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 20-216 1.42e-29

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 112.17  E-value: 1.42e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDN---EIWQDEK-----EFLPvQKRKIGFVFqdyalfp 90
Cdd:PRK13548   20 DVSLTLRPGEVVAILGPNGAGKSTLLRALSGeLSPDSGEVRLNGrplADWSPAElarrrAVLP-QHSSLSFPF------- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 nmTVLE--------NLFFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALM------NRPKLLLMDEPLS 156
Cdd:PRK13548   92 --TVEEvvamgrapHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTS 169

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 157 ALDptmrIKLQDEILQLHKEF----ETTTILVSHDpseiykL------SNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK13548  170 ALD----LAHQHHVLRLARQLaherGLAVIVVLHD------LnlaaryADRIVLLHQGRLVADGTPAEVL 229
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 20-210 1.49e-29

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 111.31  E-value: 1.49e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDN-EIWQDEKEflpvQKRKIGFVFQDYALFPNMTVLEN 97
Cdd:cd03266    23 GVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPdAGFATVDGfDVVKEPAE----ARRRLGFVSDSTGLYDRLTAREN 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFF------VNKDKELA--NHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:cd03266    99 LEYfaglygLKGDELTArlEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREF 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1441214933 170 ILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03266   179 IRQL-RALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 20-216 1.50e-29

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 117.16  E-value: 1.50e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDN-EIWQDEKEFLpvqKRKIGFVFQDYALFPNmTVLEN 97
Cdd:COG4618   350 GVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPpTAGSVRLDGaDLSQWDREEL---GRHIGYLPQDVELFDG-TIAEN 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LF-FVNKDKE-------LAN-HlleitelwELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:COG4618   426 IArFGDADPEkvvaaakLAGvH--------EMILRLPDgydtrigeggaRLSGGQRQRIGLARALYGDPRLVVLDEPNSN 497

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933 158 LDPTMRIKLQDEILQLhKEFETTTILVSHDPSeIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG4618   498 LDDEGEAALAAAIRAL-KARGATVVVITHRPS-LLAAVDKLLVLRDGRVQAFGPRDEVL 554
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
20-216 5.93e-29

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 110.59  E-value: 5.93e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNeiwQDEKEFLPVQK-RKIGFVFQDYAL-FPnMTVLE 96
Cdd:COG4559    19 DVSLTLRPGELTAIIGPNGAGKSTLLKLLTGeLTPSSGEVRLNG---RPLAAWSPWELaRRRAVLPQHSSLaFP-FTVEE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 nlfFV-----------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRAL-------MNRPKLLLMDEPLSAL 158
Cdd:COG4559    95 ---VValgraphgssaAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLaqlwepvDGGPRWLFLDEPTSAL 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 159 DptmrIKLQDEILQLHKEF---ETTTILVSHDPseiyklsN-------RVIVLKDGKIVDDGTAKSVL 216
Cdd:COG4559   172 D----LAHQHAVLRLARQLarrGGGVVAVLHDL-------NlaaqyadRILLLHQGRLVAQGTPEEVL 228
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
20-234 8.53e-29

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 110.88  E-value: 8.53e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVdNEIWQDEKEFLPVqKRKIGFVFQDY-ALFPNMTVLEN 97
Cdd:PRK13635   25 DVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLlLPEAGTITV-GGMVLSEETVWDV-RRQVGMVFQNPdNQFVGATVQDD 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFvnkdkELANHLLEITEL-----WELK--------NRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:PRK13635  103 VAF-----GLENIGVPREEMvervdQALRqvgmedflNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRR 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 165 KLQDEILQLHKEFETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGTAKSVllktsgsakFSFEGKLLDI 234
Cdd:PRK13635  178 EVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEI---------FKSGHMLQEI 237
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 20-209 1.98e-28

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 106.74  E-value: 1.98e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdEKEFLPV---QKRKIGFVFQdyalfpnmtvl 95
Cdd:cd03216    18 GVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPdSGEILVDGK----EVSFASPrdaRRAGIAMVYQ----------- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 enlffvnkdkelanhlleitelwelknrlpnsLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHK 175
Cdd:cd03216    83 --------------------------------LSVGERQMVEIARALARNARLLILDEPTAALTPAEVERLFKVIRRLRA 130

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1441214933 176 EfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDD 209
Cdd:cd03216   131 Q-GVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
20-213 2.35e-28

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 114.05  E-value: 2.35e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKV--DNEIWQDEKEFLPVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:PRK10535   26 GISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPtSGTYRVagQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAAQ 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF--------VNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP-----TMR 163
Cdd:PRK10535  106 NVEVpavyagleRKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDShsgeeVMA 185

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 164 I--KLQDeilQLHkefetTTILVSHDPsEIYKLSNRVIVLKDGKIVDDGTAK 213
Cdd:PRK10535  186 IlhQLRD---RGH-----TVIIVTHDP-QVAAQAERVIEIRDGEIVRNPPAQ 228
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 20-215 3.66e-28

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 110.21  E-value: 3.66e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNeiwQD-----EKEFLPVQkRKIGFVFQD-YA-LFPN 91
Cdd:COG4608    36 GVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPtSGEILFDG---QDitglsGRELRPLR-RRMQMVFQDpYAsLNPR 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 MTVLENL---FFVNKDKELANHLLEITELWEL-------KNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDpt 161
Cdd:COG4608   112 MTVGDIIaepLRIHGLASKAERRERVAELLELvglrpehADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALD-- 189

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 162 mrIKLQDEIL----QLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:COG4608   190 --VSIQAQVLnlleDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIAPRDEL 245
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 20-221 4.23e-28

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 108.01  E-value: 4.23e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLrSLagLEK----AQGIIKVDNeiwQDEKEF-LPVQKRKIGFVFQDYALFpNMTV 94
Cdd:cd03249    21 GLSLTIPPGKTVALVGSSGCGKSTVV-SL--LERfydpTSGEILLDG---VDIRDLnLRWLRSQIGLVSQEPVLF-DGTI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENLFF---------VNKDKELANHLLEITELwelknrlPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEP 154
Cdd:cd03249    94 AENIRYgkpdatdeeVEEAAKKANIHDFIMSL-------PDgydtlvgergsQLSGGQKQRIAIARALLRNPKILLLDEA 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 155 LSALDPTMRIKLQDEILQLHKefETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGTAKSvLLKTSG 221
Cdd:cd03249   167 TSALDAESEKLVQEALDRAMK--GRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGTHDE-LMAQKG 229
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
20-216 6.78e-28

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 108.00  E-value: 6.78e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdEKEFLPVQKR--KIGFVFQD--YALFPNMTV 94
Cdd:COG4167    31 PVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPtSGEILINGH----KLEYGDYKYRckHIRMIFQDpnTSLNPRLNI 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 ---LENLFFVNKD------KELANHLLEITELW-ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:COG4167   107 gqiLEEPLRLNTDltaeerEERIFATLRLVGLLpEHANFYPHMLSSGQKQRVALARALILQPKIIIADEALAALDMSVRS 186

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 165 KLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG4167   187 QIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVF 238
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 20-212 7.99e-28

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 106.86  E-value: 7.99e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGiikvdnEIWQDEKEF--LPVQKRK---IGFVFQDYALFPNMT 93
Cdd:cd03218    18 GVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPdSG------KILLDGQDItkLPMHKRArlgIGYLPQEASIFRKLT 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENLFFV----NKDK----ELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIK 165
Cdd:cd03218    92 VEENILAVleirGLSKkereEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPFAGVDPIAVQD 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1441214933 166 LQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTA 212
Cdd:cd03218   172 IQKIIKIL-KDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTP 217
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 20-218 9.05e-28

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 111.67  E-value: 9.05e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDN-EIWQDEKEFLpvqKRKIGFVFQDYALFPNmTVLEN 97
Cdd:TIGR01842 336 GISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPpTSGSVRLDGaDLKQWDRETF---GKHIGYLPQDVELFPG-TVAEN 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 L--FFVNKDKELANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:TIGR01842 412 IarFGENADPEKIIEAAKLAGVHELILRLPDgydtvigpggaTLSGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQ 491

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 165 KLQDEILQLHKEfETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGTAKSVLLK 218
Cdd:TIGR01842 492 ALANAIKALKAR-GITVVVITHRPSLL-GCVDKILVLQDGRIARFGERDEVLAK 543
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 20-210 1.60e-27

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 106.26  E-value: 1.60e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEI-WQDEKEFLpvqkRKIGFVF-QDYALFPNMTVLE 96
Cdd:cd03267    39 GISFTIEKGEIVGFIGPNGAGKTTTLKILSGlLQPTSGEVRVAGLVpWKRRKKFL----RRIGVVFgQKTQLWWDLPVID 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFVN-----KDKELANHLLEITELWELKNRLPN---SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:cd03267   115 SFYLLAaiydlPPARFKKRLDELSELLDLEELLDTpvrQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRN 194

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1441214933 169 EILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03267   195 FLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
cbiO PRK13650
energy-coupling factor transporter ATPase;
20-206 2.22e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 107.12  E-value: 2.22e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDEKEFlpVQKRKIGFVFQDY-ALFPNMTV--- 94
Cdd:PRK13650   25 DVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAEsGQIIIDGDLLTEENVW--DIRHKIGMVFQNPdNQFVGATVedd 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 ----LENLFFVNKD-KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:PRK13650  103 vafgLENKGIPHEEmKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKT 182

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1441214933 170 ILQLHKEFETTTILVSHDPSEIyKLSNRVIVLKDGKI 206
Cdd:PRK13650  183 IKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQV 218
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 20-206 2.85e-27

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 104.05  E-value: 2.85e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdEKEFLPVQ---KRKIGFVFQD---YALFPNM 92
Cdd:cd03215    18 DVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPaSGEITLDGK----PVTRRSPRdaiRAGIAYVPEDrkrEGLVLDL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  93 TVLENLFfvnkdkelanhlleitelwelknrLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDptmrIKLQDEILQ 172
Cdd:cd03215    94 SVAENIA------------------------LSSLLSGGNQQKVVLARWLARDPRVLILDEPTRGVD----VGAKAEIYR 145

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1441214933 173 LHKEFE---TTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:cd03215   146 LIRELAdagKAVLLISSELDELLGLCDRILVMYEGRI 182
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
21-216 4.96e-27

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 105.35  E-value: 4.96e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVD-NEI--WQDEKeflpVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:PRK11614   24 VSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRAtSGRIVFDgKDItdWQTAK----IMREAVAIVPEGRRVFSRMTVEE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NL----FFVNKDKelanHLLEITELWELKNRL-------PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIK 165
Cdd:PRK11614  100 NLamggFFAERDQ----FQERIKWVYELFPRLherriqrAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQ 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 166 LQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK11614  176 IFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALL 225
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 20-260 5.59e-27

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 105.84  E-value: 5.59e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQdeKEFLPVQKRKIGFVFQDY-ALFPNMTV--- 94
Cdd:PRK13632   27 NVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQsGEIKIDGITIS--KENLKEIRKKIGIIFQNPdNQFIGATVedd 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 ----LEN-LFFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:PRK13632  105 iafgLENkKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKI 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 170 ILQLHKEFETTTILVSHDPSEIYkLSNRVIVLKDGKIVDDGTAKSVLLktsgsakfsfEGKLLDIIKVDVIYVAIIAIGQ 249
Cdd:PRK13632  185 MVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGKPKEILN----------NKEILEKAKIDSPFIYKLSKKL 253

                         250
                  ....*....|.
gi 1441214933 250 QLVEVTISSNE 260
Cdd:PRK13632  254 KGIDPTYNEEE 264
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 21-216 5.86e-27

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 105.50  E-value: 5.86e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVD------NEIWQDEKEFLPVQKRKIGFVFQDYALFPnMTV 94
Cdd:PRK14258   26 VSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESEVRVEgrveffNQNIYERRVNLNRLRRQVSMVHPKPNLFP-MSV 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENLFFVNKD---------KELANHLLEITELW-ELKNRLPNS---LSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPT 161
Cdd:PRK14258  105 YDNVAYGVKIvgwrpkleiDDIVESALKDADLWdEIKHKIHKSaldLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPI 184

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 162 MRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKD-----GKIVDDGTAKSVL 216
Cdd:PRK14258  185 ASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKKIF 244
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
20-215 6.12e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 105.94  E-value: 6.12e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSL-AGLEKAQGIIKVDNEIWQDEKEFLPVqKRKIGFVFQ-------------D 85
Cdd:PRK13633   28 DVNLEVKKGEFLVILGRNGSGKSTIAKHMnALLIPSEGKVYVDGLDTSDEENLWDI-RNKAGMVFQnpdnqivativeeD 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  86 YALFPnmtvlENLFFVNKD-KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:PRK13633  107 VAFGP-----ENLGIPPEEiRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRR 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 165 KLQDEILQLHKEFETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK13633  182 EVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEI 231
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 18-215 1.92e-26

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 107.81  E-value: 1.92e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  18 NLDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdekeflPVQ--------KRKIGFVFQDYAL 88
Cdd:COG3845    21 NDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPdSGEILIDGK---------PVRirsprdaiALGIGMVHQHFML 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  89 FPNMTVLENL---------FFVNKdKELANHLLEITELWELK---NRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:COG3845    92 VPNLTVAENIvlgleptkgGRLDR-KAARARIRELSERYGLDvdpDAKVEDLSVGEQQRVEILKALYRGARILILDEPTA 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 157 ALDP--------TMRiKLQDEilqlhkefETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:COG3845   171 VLTPqeadelfeILR-RLAAE--------GKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTAET 228
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 20-218 2.24e-26

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 103.46  E-value: 2.24e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNeiwQDEKEF-LPVQKRKIGFVFQDYALFpNMTVLEN 97
Cdd:cd03253    19 DVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFyDVSSGSILIDG---QDIREVtLDSLRRAIGVVPQDTVLF-NDTIGYN 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNKD--KELANHLLEITELWELKNRLPNS-----------LSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:cd03253    95 IRYGRPDatDEEVIEAAKAAQIHDKIMRFPDGydtivgerglkLSGGEKQRVAIARAILKNPPILLLDEATSALDTHTER 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 165 KLQDEILQLHKefETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGTAKSVLLK 218
Cdd:cd03253   175 EIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEELLAK 225
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 20-201 4.28e-26

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 106.99  E-value: 4.28e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNeiwQDEKEFLPVQKRK-IGFVFQDYALFPNmTVLEN 97
Cdd:TIGR02857 340 PVSFTVPPGERVALVGPSGAGKSTLLNLLLGFvDPTEGSIAVNG---VPLADADADSWRDqIAWVPQHPFLFAG-TIAEN 415

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNKD---KELANhLLEITELWELKNRLP-----------NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:TIGR02857 416 IRLARPDasdAEIRE-ALERAGLDEFVAALPqgldtpigeggAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETE 494

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1441214933 164 IKLQDEILQLHKefETTTILVSHDPSEIYkLSNRVIVL 201
Cdd:TIGR02857 495 AEVLEALRALAQ--GRTVLLVTHRLALAA-LADRIVVL 529
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
20-215 5.56e-26

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 103.31  E-value: 5.56e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNE-IWQDEKEFLPVQKRKIGFVFQDYALFPNMTVLEN 97
Cdd:PRK11831   25 NISLTVPRGKITAIMGPSGIGKTTLLRLIGGqIAPDHGEILFDGEnIPAMSRSRLYTVRKRMSMLFQSGALFTDMNVFDN 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFF-VNKDKELANHLLEITELWELK--------NRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP-TMRI--K 165
Cdd:PRK11831  105 VAYpLREHTQLPAPLLHSTVMMKLEavglrgaaKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPiTMGVlvK 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1441214933 166 LQDEilqLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK11831  185 LISE---LNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 20-216 5.95e-26

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 106.69  E-value: 5.95e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKT----TLLRSLA-GLEKAQGIIKVDNE--IWQDEKEFLPVQKRKIGFVFQD--YALFP 90
Cdd:COG4172    28 GVSFDIAAGETLALVGESGSGKSvtalSILRLLPdPAAHPSGSILFDGQdlLGLSERELRRIRGNRIAMIFQEpmTSLNP 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTV----LENLFF---VNKD--KELANHLLEITELWELKNRL---PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSAL 158
Cdd:COG4172   108 LHTIgkqiAEVLRLhrgLSGAaaRARALELLERVGIPDPERRLdayPHQLSGGQRQRVMIAMALANEPDLLIADEPTTAL 187

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 159 DPTmrikLQDEILQL----HKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG4172   188 DVT----VQAQILDLlkdlQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAELF 245
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
21-216 7.52e-26

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 102.35  E-value: 7.52e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNE---IWQD--------EKEFLPVQKRKIGFVFQDYAL 88
Cdd:PRK10619   24 VSLQANAGDVISIIGSSGSGKSTFLRCINFLEKpSEGSIVVNGQtinLVRDkdgqlkvaDKNQLRLLRTRLTMVFQHFNL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  89 FPNMTVLENLFFV---------NKDKELANHLLE---ITElwELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:PRK10619  104 WSHMTVLENVMEApiqvlglskQEARERAVKYLAkvgIDE--RAQGKYPVHLSGGQQQRVSIARALAMEPEVLLFDEPTS 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 157 ALDPtmriKLQDEILQLHKEFE---TTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK10619  182 ALDP----ELVGEVLRIMQQLAeegKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLF 240
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 10-204 7.86e-26

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 101.74  E-value: 7.86e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  10 LHGSNG----VMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQG--IIKVDNEIWQD-----EKEFLPVQKRK 78
Cdd:COG4778    16 LHLQGGkrlpVLD-GVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSgsILVRHDGGWVDlaqasPREILALRRRT 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  79 IGFVFQdyalF----PNMT----VLENLFFVNKDKELAN-------HLLEITE-LWELKnrlPNSLSGGQKQRVSLCRAL 142
Cdd:COG4778    95 IGYVSQ----FlrviPRVSaldvVAEPLLERGVDREEARararellARLNLPErLWDLP---PATFSGGEQQRVNIARGF 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 143 MNRPKLLLMDEPLSALDPTMRIKLQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDG 204
Cdd:COG4778   168 IADPPLLLLDEPTASLDAANRAVVVELIEEA-KARGTAIIGIFHDEEVREAVADRVVDVTPF 228
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 20-215 8.46e-26

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 101.45  E-value: 8.46e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEiwqdEKEFLPVQKRK---IGFVFQDYALFPNMTVL 95
Cdd:TIGR03410  18 GVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKsGSIRLDGE----DITKLPPHERAragIAYVPQGREIFPRLTVE 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLFFV-----NKDKELANHLLEITE-LWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:TIGR03410  94 ENLLTGlaalpRRSRKIPDEIYELFPvLKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEPTEGIQPSIIKDIGRV 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1441214933 170 ILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:TIGR03410 174 IRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 20-232 2.24e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 102.09  E-value: 2.24e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL------------------EKAQGIIKVDNEIWQDEKEFLPVQK----- 76
Cdd:PRK13651   25 NVSVEINQGEFIAIIGQTGSGKTTFIEHLNALllpdtgtiewifkdeknkKKTKEKEKVLEKLVIQKTRFKKIKKikeir 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  77 RKIGFVFQ--DYALFPNmTVLENLFF------VNKD--KELANHLLEITELWE--LKnRLPNSLSGGQKQRVSLCRALMN 144
Cdd:PRK13651  105 RRVGVVFQfaEYQLFEQ-TIEKDIIFgpvsmgVSKEeaKKRAAKYIELVGLDEsyLQ-RSPFELSGGQKRRVALAGILAM 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 145 RPKLLLMDEPLSALDPTMRIKLQDEILQLHKEFEtTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKTsgsaK 224
Cdd:PRK13651  183 EPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGK-TIILVTHDLDNVLEWTKRTIFFKDGKIIKDGDTYDILSDN----K 257


                  ....*...
gi 1441214933 225 FSFEGKLL 232
Cdd:PRK13651  258 FLIENNME 265
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
21-213 2.45e-25

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 101.24  E-value: 2.45e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGL---EKAQG--IIKVDNEIWQDEKEFLPVQKRK--IGFVFQDYALFPNMT 93
Cdd:PRK09984   23 VDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgDKSAGshIELLGRTVQREGRLARDIRKSRanTGYIFQQFNLVNRLS 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENL----------------FFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:PRK09984  103 VLENVligalgstpfwrtcfsWFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARALMQQAKVILADEPIAS 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 158 LDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAK 213
Cdd:PRK09984  183 LDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQ 238
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
1-207 2.60e-25

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 100.33  E-value: 2.60e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIE--IKKELHGSNGVMNLDVNLdiRSKDFVALTGLSGSGKTTLLRSLAGLEK--AQGIIKVDNEIWQDEKEFLPVQK 76
Cdd:PRK10908    1 MIRFEhvSKAYLGGRQALQGVTFHM--RPGEMAFLTGHSGAGKSTLLKLICGIERpsAGKIWFSGHDITRLKNREVPFLR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  77 RKIGFVFQDYALFPNMTVLEN----LFFVNKDKE-----LANHLLEITELWELKNrLPNSLSGGQKQRVSLCRALMNRPK 147
Cdd:PRK10908   79 RQIGMIFQDHHLLMDRTVYDNvaipLIIAGASGDdirrrVSAALDKVGLLDKAKN-FPIQLSGGEQQRVGIARAVVNKPA 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 148 LLLMDEPLSALDPTmrikLQDEILQLHKEFE---TTTILVSHDPSEIYKLSNRVIVLKDGKIV 207
Cdd:PRK10908  158 VLLADEPTGNLDDA----LSEGILRLFEEFNrvgVTVLMATHDIGLISRRSYRMLTLSDGHLH 216
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 20-205 2.63e-25

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 99.47  E-value: 2.63e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVdneiwqdekeflpvqKRKIGFVFQdYALFPNMTVLEN- 97
Cdd:cd03250    23 DINLEVPKGELVAIVGPVGSGKSSLLSALLGeLEKLSGSVSV---------------PGSIAYVSQ-EPWIQNGTIRENi 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNKDKELANHLLEITELWE-LKNrLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIK 165
Cdd:cd03250    87 LFGKPFDEERYEKVIKACALEPdLEI-LPDgdlteigekgiNLSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGRH 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1441214933 166 LQDEILQLHKEFETTTILVSHdpsEIYKLS--NRVIVLKDGK 205
Cdd:cd03250   166 IFENCILGLLLNNKTRILVTH---QLQLLPhaDQIVVLDNGR 204
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 2-215 2.73e-25

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 104.79  E-value: 2.73e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   2 IKIEIKKELHGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQ--DEKEFLPVqKRKI 79
Cdd:PRK15134  287 IRKGILKRTVDHNVVVK-NISFTLRPGETLGLVGESGSGKSTTGLALLRLINSQGEIWFDGQPLHnlNRRQLLPV-RHRI 364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  80 GFVFQD--YALFPNMTVLE-----------NLFFVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRP 146
Cdd:PRK15134  365 QVVFQDpnSSLNPRLNVLQiieeglrvhqpTLSAAQREQQVIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILKP 444

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 147 KLLLMDEPLSALDPTmrikLQDEILQLHKEFETT----TILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK15134  445 SLIILDEPTSSLDKT----VQAQILALLKSLQQKhqlaYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERV 513
cbiO PRK13643
energy-coupling factor transporter ATPase;
19-216 3.21e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 101.73  E-value: 3.21e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  19 LDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEI---WQDEKEFLPVQKrKIGFVFQ--DYALFPNm 92
Cdd:PRK13643   23 FDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLlQPTEGKVTVGDIVvssTSKQKEIKPVRK-KVGVVFQfpESQLFEE- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  93 TVLENLFF------VNKDK--ELANHLLEIT----ELWElknRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP 160
Cdd:PRK13643  101 TVLKDVAFgpqnfgIPKEKaeKIAAEKLEMVgladEFWE---KSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDP 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 161 TMRIKLQDEILQLHKEFEtTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK13643  178 KARIEMMQLFESIHQSGQ-TVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVF 232
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 20-215 3.34e-25

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 101.72  E-value: 3.34e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdekEFLPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:COG4152    19 DVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPdSGEVLWDGE------PLDPEDRRRIGYLPEERGLYPKMKVGEQL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFV--------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:COG4152    93 VYLarlkglskAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLKDVI 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1441214933 171 LQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:COG4152   173 RELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEI 216
cbiO PRK13649
energy-coupling factor transporter ATPase;
20-215 8.38e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 100.20  E-value: 8.38e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLE-KAQGIIKVDN-EIWQDE--KEFLPVQKrKIGFVFQdyalFPNM--- 92
Cdd:PRK13649   25 DVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHvPTQGSVRVDDtLITSTSknKDIKQIRK-KVGLVFQ----FPESqlf 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  93 --TVLENLFF------VNKDK--ELAN---HLLEITElwELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALD 159
Cdd:PRK13649  100 eeTVLKDVAFgpqnfgVSQEEaeALAReklALVGISE--SLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLD 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 160 PTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK13649  178 PKGRKELMTLFKKLHQS-GMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDI 232
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 20-215 1.04e-24

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 100.95  E-value: 1.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVD-----NEIWQ-DEKEFLPVQKRKIGFVFQD--YALFPN 91
Cdd:PRK09473   34 DLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSatfngREILNlPEKELNKLRAEQISMIFQDpmTSLNPY 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 MTVLENLFFV-------NKDK--ELANHLLEITELWELKNRL---PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALD 159
Cdd:PRK09473  114 MRVGEQLMEVlmlhkgmSKAEafEESVRMLDAVKMPEARKRMkmyPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALD 193

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 160 PTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK09473  194 VTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDV 249
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 20-215 1.69e-24

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 100.17  E-value: 1.69e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA---------QGIIKVDNEIWQDekeflpvqKRK-IGFVFQD--YA 87
Cdd:PRK15079   39 GVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKAtdgevawlgKDLLGMKDDEWRA--------VRSdIQMIFQDplAS 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  88 LFPNMTVLE------NLFFVNKDKE-----LANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:PRK15079  111 LNPRMTIGEiiaeplRTYHPKLSRQevkdrVKAMMLKVGLLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVS 190

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933 157 ALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK15079  191 ALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEV 249
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 20-216 1.77e-24

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 98.43  E-value: 1.77e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEiwqdEKEFLPVQ---KRKIGFVFQDYALFPNMTVL 95
Cdd:PRK10895   21 DVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIvPRDAGNIIIDDE----DISLLPLHaraRRGIGYLPQEASIFRRLSVY 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLFFV---------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKL 166
Cdd:PRK10895   97 DNLMAVlqirddlsaEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDI 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1441214933 167 QdEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK10895  177 K-RIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEIL 225
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 20-210 2.29e-24

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 97.60  E-value: 2.29e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIwqdekeflpvqkrkIGFVFQDYALFPNMTVLENL 98
Cdd:cd03220    40 DVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPdSGTVTVRGRV--------------SSLLGLGGGFNPELTGRENI 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFV-----NKDKELANHLLEITELWELKNR--LP-NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:cd03220   106 YLNgrllgLSRKEIDEKIDEIIEFSELGDFidLPvKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRL 185

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1441214933 171 LQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:cd03220   186 RELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
cbiO PRK13641
energy-coupling factor transporter ATPase;
20-215 2.31e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 99.13  E-value: 2.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNE--IWQDEKEFLPVQKRKIGFVFQ--DYALFPNmTV 94
Cdd:PRK13641   25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKpSSGTITIAGYhiTPETGNKNLKKLRKKVSLVFQfpEAQLFEN-TV 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENLFFVNKD--------KELANHLLEITELWE-LKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPtmriK 165
Cdd:PRK13641  104 LKDVEFGPKNfgfsedeaKEKALKWLKKVGLSEdLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDP----E 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 166 LQDEILQLHKEFET---TTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK13641  180 GRKEMMQLFKDYQKaghTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEI 232
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 20-216 2.86e-24

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 97.94  E-value: 2.86e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVD-NEIWQDEKEFLpvqKRKIGFVFQDYALFpNMTVLEN 97
Cdd:cd03252    20 NISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPeNGRVLVDgHDLALADPAWL---RRQVGVVLQENVLF-NRSIRDN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNK--DKE-------LANHLLEITELWELKNRLPN----SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:cd03252    96 IALADPgmSMErvieaakLAGAHDFISELPEGYDTIVGeqgaGLSGGQRQRIAIARALIHNPRILIFDEATSALDYESEH 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 165 KLQDEILQLHKefETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:cd03252   176 AIMRNMHDICA--GRTVIIIAHRLSTV-KNADRIIVMEKGRIVEQGSHDELL 224
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 20-207 3.20e-24

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 97.34  E-value: 3.20e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKvdNEIWQDEKEFLPVQ-KRKIGFVFQDYALFPNMTVLENL 98
Cdd:cd03234    25 DVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGTTS--GQILFNGQPRKPDQfQKCVAYVRQDDILLPGLTVRETL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFV------------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTmrikL 166
Cdd:cd03234   103 TYTailrlprkssdaIRKKRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSF----T 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1441214933 167 QDEILQLHKEFETT--TILVS-HDP-SEIYKLSNRVIVLKDGKIV 207
Cdd:cd03234   179 ALNLVSTLSQLARRnrIVILTiHQPrSDLFRLFDRILLLSSGEIV 223
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 20-211 4.91e-24

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 96.79  E-value: 4.91e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEIWQDekefLPVQK--RKIGFVFQDYALFPNmTVLE 96
Cdd:cd03244    22 NISFSIKPGEKVGIVGRTGSGKSSLLLALFRLvELSSGSILIDGVDISK----IGLHDlrSRISIIPQDPVLFSG-TIRS 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFVNK--DKELaNHLLEITELWELKNRLP-----------NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTmr 163
Cdd:cd03244    97 NLDPFGEysDEEL-WQALERVGLKEFVESLPggldtvveeggENLSVGQRQLLCLARALLRKSKILVLDEATASVDPE-- 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 164 iklQDEILQ--LHKEF-ETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGT 211
Cdd:cd03244   174 ---TDALIQktIREAFkDCTVLTIAHRLDTIID-SDRILVLDKGRVVEFDS 220
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 20-216 6.35e-24

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 97.43  E-value: 6.35e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEIWQDEKEFLPVQ----KRKIGFVFQDYALFPNMTV 94
Cdd:PRK14246   28 DITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLiEIYDSKIKVDGKVLYFGKDIFQIDaiklRKEVGMVFQQPNPFPHLSI 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENLFFVNKD---------KELANHLLEITELW-ELKNRL---PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPT 161
Cdd:PRK14246  108 YDNIAYPLKShgikekreiKKIVEECLRKVGLWkEVYDRLnspASQLSGGQQQRLTIARALALKPKVLLMDEPTSMIDIV 187

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 162 MRIKLQDEILQLHKEFetTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK14246  188 NSQAIEKLITELKNEI--AIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIF 240
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 20-216 1.01e-23

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 96.25  E-value: 1.01e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdEKEFLPVQKRK---IGFVFQDYALFPNMTVL 95
Cdd:COG1137    21 DVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPdSGRIFLDGE----DITHLPMHKRArlgIGYLPQEASIFRKLTVE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENL------FFVNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:COG1137    97 DNIlavlelRKLSKKerEERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFILLDEPFAGVDPIAVADIQ 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 168 DEILQLhkefetTT----ILVS-HDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1137   177 KIIRHL------KErgigVLITdHNVRETLGICDRAYIISEGKVLAEGTPEEIL 224
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 21-211 1.12e-23

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 100.30  E-value: 1.12e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNeiwQDEKEFLPVQKRK-IGFVFQDYALFPNmTVLENLF 99
Cdd:PRK11174  369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPYQGSLKING---IELRELDPESWRKhLSWVGQNPQLPHG-TLRDNVL 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 100 FVNKD--KELANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKL 166
Cdd:PRK11174  445 LGNPDasDEQLQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQLV 524

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1441214933 167 QDEILQLHKefETTTILVSHDPSEIYKLsNRVIVLKDGKIVDDGT 211
Cdd:PRK11174  525 MQALNAASR--RQTTLMVTHQLEDLAQW-DQIWVMQDGQIVQQGD 566
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 20-187 1.37e-23

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 96.77  E-value: 1.37e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLE------KAQG-IIKVDNEIWqdEKEFLPVQ-KRKIGFVFQDYALFPN 91
Cdd:PRK14243   28 NVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNdlipgfRVEGkVTFHGKNLY--APDVDPVEvRRRIGMVFQKPNPFPK 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 mTVLENLFF---VNKDK----ELANHLLEITELW-ELKNRLPNS---LSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP 160
Cdd:PRK14243  106 -SIYDNIAYgarINGYKgdmdELVERSLRQAALWdEVKDKLKQSglsLSGGQQQRLCIARAIAVQPEVILMDEPCSALDP 184

                         170       180
                  ....*....|....*....|....*..
gi 1441214933 161 TMRIKLQDEILQLHKEFetTTILVSHD 187
Cdd:PRK14243  185 ISTLRIEELMHELKEQY--TIIIVTHN 209
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 20-208 2.02e-23

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 99.37  E-value: 2.02e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIwqdekeflpvqkrKIGFVFQDYALF-PNMTVLEN 97
Cdd:COG0488   333 DLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDsGTVKLGETV-------------KIGYFDQHQEELdPDKTVLDE 399

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LffvnkdKELANHLLEItelwELKNRL------------P-NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRi 164
Cdd:COG0488   400 L------RDGAPGGTEQ----EVRGYLgrflfsgddafkPvGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIETL- 468

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1441214933 165 klqdEIL-QLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVD 208
Cdd:COG0488   469 ----EALeEALDDFPGTVLLVSHDRYFLDRVATRILEFEDGGVRE 509
cbiO PRK13644
energy-coupling factor transporter ATPase;
20-216 2.36e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 96.21  E-value: 2.36e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQDEKEFLPVQKRKIGFVFQD-YALFPNMTVLENL 98
Cdd:PRK13644   20 NINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQGIRKLVGIVFQNpETQFVGRTVEEDL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFVNKD--------KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:PRK13644  100 AFGPENlclppieiRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVLERI 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1441214933 171 LQLHKEFEtTTILVSHDPSEIYkLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK13644  180 KKLHEKGK-TIVYITHNLEELH-DADRIIVMDRGKIVLEGEPENVL 223
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 12-188 2.66e-23

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 98.97  E-value: 2.66e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  12 GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEIWQDEKEFLPvqKRKIGFVFQDYALFp 90
Cdd:TIGR02868 346 GAPPVLD-GVSLDLPPGERVAILGPSGSGKSTLLATLAGlLDPLQGEVTLDGVPVSSLDQDEV--RRRVSVCAQDAHLF- 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLENLFFVNK---DKELANhLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:TIGR02868 422 DTTVRENLRLARPdatDEELWA-ALERVGLADWLRALPDgldtvlgeggaRLSGGERQRLALARALLADAPILLLDEPTE 500

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1441214933 157 ALDPTMRIKLQDEILQlhKEFETTTILVSHDP 188
Cdd:TIGR02868 501 HLDAETADELLEDLLA--ALSGRTVVLITHHL 530
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 7-211 7.09e-23

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 97.81  E-value: 7.09e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   7 KKELHGSNGVmnldvnldIRSKDFVALTGLSGSGKTTLL-----RSLAGLEKaQGIIKVDNEiwqdekeflPVQKRKI-- 79
Cdd:TIGR00955  38 KHLLKNVSGV--------AKPGELLAVMGSSGAGKTTLMnalafRSPKGVKG-SGSVLLNGM---------PIDAKEMra 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  80 --GFVFQDYALFPNMTVLENLFF---------VNKD--KELANHLLEITELWELKNRL---PN---SLSGGQKQRVSLCR 140
Cdd:TIGR00955 100 isAYVQQDDLFIPTLTVREHLMFqahlrmprrVTKKekRERVDEVLQALGLRKCANTRigvPGrvkGLSGGERKRLAFAS 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 141 ALMNRPKLLLMDEPLSALDPTMriklQDEILQLHKEFET---TTILVSHDPS-EIYKLSNRVIVLKDGKIVDDGT 211
Cdd:TIGR00955 180 ELLTDPPLLFCDEPTSGLDSFM----AYSVVQVLKGLAQkgkTIICTIHQPSsELFELFDKIILMAEGRVAYLGS 250
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
20-207 9.65e-23

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 97.01  E-value: 9.65e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdekeflPVQ--------KRKIGFVFQD---YA 87
Cdd:COG1129   270 DVSFSVRAGEILGIAGLVGAGRTELARALFGADPAdSGEIRLDGK---------PVRirsprdaiRAGIAYVPEDrkgEG 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  88 LFPNMTVLENL-----------FFVNKDKE--LANHLLEitelwELKNRLPN------SLSGGQKQRVSLCRALMNRPKL 148
Cdd:COG1129   341 LVLDLSIRENItlasldrlsrgGLLDRRREraLAEEYIK-----RLRIKTPSpeqpvgNLSGGNQQKVVLAKWLATDPKV 415

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 149 LLMDEplsaldPTMRIklqD-----EILQLHKEFE---TTTILVSHDPSEIYKLSNRVIVLKDGKIV 207
Cdd:COG1129   416 LILDE------PTRGI---DvgakaEIYRLIRELAaegKAVIVISSELPELLGLSDRILVMREGRIV 473
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
20-211 1.12e-22

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 93.34  E-value: 1.12e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLE---------KAQGIIKVDNEIWQDekeflpVQKRKIGFVFQDYALFP 90
Cdd:PRK11629   27 NVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDtptsgdvifNGQPMSKLSSAAKAE------LRNQKLGFIYQFHHLLP 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLENL---FFVNKDK-----ELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDptm 162
Cdd:PRK11629  101 DFTALENVampLLIGKKKpaeinSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLD--- 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 163 rIKLQDEILQLHKEFE----TTTILVSHDPSEIYKLSnRVIVLKDGKIVDDGT 211
Cdd:PRK11629  178 -ARNADSIFQLLGELNrlqgTAFLVVTHDLQLAKRMS-RQLEMRDGRLTAELS 228
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 21-216 1.36e-22

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 94.39  E-value: 1.36e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEI---------WQDEKEFlpvqKRKIGFVFQDYALFPn 91
Cdd:PRK14271   40 VSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVllggrsifnYRDVLEF----RRRVGMLFQRPNPFP- 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 MTVLENLFFVNKDKEL---------ANHLLEITELWE-LKNRLPNS---LSGGQKQRVSLCRALMNRPKLLLMDEPLSAL 158
Cdd:PRK14271  115 MSIMDNVLAGVRAHKLvprkefrgvAQARLTEVGLWDaVKDRLSDSpfrLSGGQQQLLCLARTLAVNPEVLLLDEPTSAL 194

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 159 DPTMRIKLQDEILQLHKEFetTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK14271  195 DPTTTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLF 250
cbiO PRK13642
energy-coupling factor transporter ATPase;
1-220 1.79e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 94.00  E-value: 1.79e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   1 MIKIEIKKELHGSNGVmnldvNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEIWQDEKEFlpVQKRKI 79
Cdd:PRK13642   11 VFKYEKESDVNQLNGV-----SFSITKGEWVSIIGQNGSGKSTTARLIDGLfEEFEGKVKIDGELLTAENVW--NLRRKI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  80 GFVFQDY-ALFPNMTVLENLFFVNKD---------KELANHLLEITELwELKNRLPNSLSGGQKQRVSLCRALMNRPKLL 149
Cdd:PRK13642   84 GMVFQNPdNQFVGATVEDDVAFGMENqgipreemiKRVDEALLAVNML-DFKTREPARLSGGQKQRVAVAGIIALRPEII 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 150 LMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGtAKSVLLKTS 220
Cdd:PRK13642  163 ILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEA-APSELFATS 231
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 4-217 3.02e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 93.26  E-value: 3.02e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   4 IEIKkELH-----GSNGVMNLDVNLDIRSKdfVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKV-DNEIWQDEKEFLpvqK 76
Cdd:PRK13647    5 IEVE-DLHfrykdGTKALKGLSLSIPEGSK--TALLGPNGAGKSTLLLHLNGIYLPQrGRVKVmGREVNAENEKWV---R 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  77 RKIGFVFQDY--ALFpNMTVLENLFF--VNKD------KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRP 146
Cdd:PRK13647   79 SKVGLVFQDPddQVF-SSTVWDDVAFgpVNMGldkdevERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDP 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 147 KLLLMDEPLSALDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGtAKSVLL 217
Cdd:PRK13647  158 DVIVLDEPMAYLDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEG-DKSLLT 226
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 20-216 3.52e-22

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 92.45  E-value: 3.52e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEI-WQDEkeflpvqkrkIGFVFQdyalfPNMTVLEN 97
Cdd:COG1134    44 DVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPtSGRVEVNGRVsALLE----------LGAGFH-----PELTGREN 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFV-----NKDKELANHLLEITELWELKN--RLP-NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:COG1134   109 IYLNgrllgLSRKEIDEKFDEIVEFAELGDfiDQPvKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLAR 188

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1441214933 170 ILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG1134   189 IRELRES-GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVI 234
cbiO PRK13640
energy-coupling factor transporter ATPase;
20-221 3.78e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 92.94  E-value: 3.78e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL----EKAQGIIKVDNeIWQDEKEFLPVqKRKIGFVFQDY-ALFPNMTV 94
Cdd:PRK13640   25 DISFSIPRGSWTALIGHNGSGKSTISKLINGLllpdDNPNSKITVDG-ITLTAKTVWDI-REKVGIVFQNPdNQFVGATV 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENLFF--------VNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKL 166
Cdd:PRK13640  103 GDDVAFglenravpRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQI 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 167 QDEILQLHKEFETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGT-----AKSVLLKTSG 221
Cdd:PRK13640  183 LKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSpveifSKVEMLKEIG 241
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 20-206 4.49e-22

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 95.52  E-value: 4.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIwqdekeflpvqkrKIGFVFQDYALFPNMTVLENL 98
Cdd:COG0488    16 DVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPdSGEVSIPKGL-------------RIGYLPQEPPLDDDLTVLDTV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFVNKD-------KELANHLL--------EITEL---------WELK-----------------NRLPNSLSGGQKQRVS 137
Cdd:COG0488    83 LDGDAElraleaeLEELEAKLaepdedleRLAELqeefealggWEAEaraeeilsglgfpeedlDRPVSELSGGWRRRVA 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933 138 LCRALMNRPKLLLMDEPLSALDPTMRIKLQDEIlqlhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:COG0488   163 LARALLSEPDLLLLDEPTNHLDLESIEWLEEFL----KNYPGTVLVVSHDRYFLDRVATRILELDRGKL 227
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 20-205 4.54e-22

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 89.43  E-value: 4.54e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDneiwqdekeflpvQKRKIGFVFQdyalfpnmtvlenl 98
Cdd:cd03221    18 DISLTINPGDRIGLVGRNGAGKSTLLKLIAGeLEPDEGIVTWG-------------STVKIGYFEQ-------------- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 ffvnkdkelanhlleitelwelknrlpnsLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEIlqlhKEFE 178
Cdd:cd03221    71 -----------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEALEEAL----KEYP 117

                         170       180
                  ....*....|....*....|....*..
gi 1441214933 179 TTTILVSHDPSEIYKLSNRVIVLKDGK 205
Cdd:cd03221   118 GTVILVSHDRYFLDQVATKIIELEDGK 144
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 20-216 4.81e-22

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 92.30  E-value: 4.81e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDN--EIWQDEKEFLPVQKRKI-----GFVFQDYALFPN 91
Cdd:PRK11701   24 DVSFDLYPGEVLGIVGESGSGKTTLLNALSArLAPDAGEVHYRMrdGQLRDLYALSEAERRRLlrtewGFVHQHPRDGLR 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 MTVL------ENLFFVN-----KDKELANHLLEITELWElkNR---LPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:PRK11701  104 MQVSaggnigERLMAVGarhygDIRATAGDWLERVEIDA--ARiddLPTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGG 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933 158 LDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK11701  182 LDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESGLTDQVL 240
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 32-215 5.50e-22

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 93.49  E-value: 5.50e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  32 ALTGLSGSGKTTLLRSLAGLEK-AQGIIKVD-NEIWQDEKEFLPVQKRKIGFVFQD-YA-LFPNMTV---LENLFFVNKD 104
Cdd:PRK11308   45 AVVGESGCGKSTLARLLTMIETpTGGELYYQgQDLLKADPEAQKLLRQKIQIVFQNpYGsLNPRKKVgqiLEEPLLINTS 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 105 ---KELANHLLEITELWELK----NRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEF 177
Cdd:PRK11308  125 lsaAERREKALAMMAKVGLRpehyDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQEL 204

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1441214933 178 ETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK11308  205 GLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQI 242
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 6-215 6.97e-22

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 94.92  E-value: 6.97e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   6 IKKELHGSNgvmnlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQG--IIKVDNEIWQDEKEFLPVQKRKIGFVF 83
Cdd:PRK10261  333 VTREVHAVE-----KVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGgeIIFNGQRIDTLSPGKLQALRRDIQFIF 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  84 QD-YA-LFPNMTV---------LENLFFVNKDKELANHLLEITELW-ELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLM 151
Cdd:PRK10261  408 QDpYAsLDPRQTVgdsimeplrVHGLLPGKAAAARVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIA 487

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 152 DEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK10261  488 DEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAV 551
galliderm_ABC TIGR03740
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ...
 20-206 7.37e-22

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.


Pssm-ID: 163452 [Multi-domain]  Cd Length: 223  Bit Score: 90.92  E-value: 7.37e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEIWQDEkeflpvQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:TIGR03740  18 NISLTVPKNSVYGLLGPNGAGKSTLLKMITGiLRPTSGEIIFDGHPWTRK------DLHKIGSLIESPPLYENLTARENL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFVNK----DKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPtmrIKLQD--EILQ 172
Cdd:TIGR03740  92 KVHTTllglPDSRIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLILDEPTNGLDP---IGIQElrELIR 168

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1441214933 173 LHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:TIGR03740 169 SFPEQGITVILSSHILSEVQQLADHIGIISEGVL 202
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 20-217 9.73e-22

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 94.81  E-value: 9.73e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQD-EKEFLpvqKRKIGFVFQDYALFPNmTVLEN 97
Cdd:TIGR01193 492 DISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARsGEILLNGFSLKDiDRHTL---RQFINYLPQEPYIFSG-SILEN 567

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNKDKELANHLLEITELWELKNRLPN--------------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:TIGR01193 568 LLLGAKENVSQDEIWAACEIAEIKDDIENmplgyqtelseegsSISGGQKQRIALARALLTDSKVLILDESTSNLDTITE 647

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 164 IKLQDEILQLHkefETTTILVSHDPSeIYKLSNRVIVLKDGKIVDDGTAKSVLL 217
Cdd:TIGR01193 648 KKIVNNLLNLQ---DKTIIFVAHRLS-VAKQSDKIIVLDHGKIIEQGSHDELLD 697
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 21-215 1.14e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 91.68  E-value: 1.14e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVD-NEIWQDEKEFLPVQKrKIGFVFQ--DYALFPNmTVLE 96
Cdd:PRK13639   21 INFKAEKGEMVALLGPNGAGKSTLFLHFNGiLKPTSGEVLIKgEPIKYDKKSLLEVRK-TVGIVFQnpDDQLFAP-TVEE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF------VNKD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:PRK13639   99 DVAFgplnlgLSKEevEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMK 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1441214933 169 EILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK13639  179 LLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEV 224
cbiO PRK13645
energy-coupling factor transporter ATPase;
20-211 1.21e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 91.99  E-value: 1.21e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL---EKAQGIIKvDNEIWQDEKEFLPVQ--KRKIGFVFQ--DYALFPNm 92
Cdd:PRK13645   29 NTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLiisETGQTIVG-DYAIPANLKKIKEVKrlRKEIGLVFQfpEYQLFQE- 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  93 TVLENLFF----VNKDKELA----NHLLEITEL-WELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:PRK13645  107 TIEKDIAFgpvnLGENKQEAykkvPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGE 186

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1441214933 164 IKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:PRK13645  187 EDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGS 234
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 12-201 1.64e-21

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 90.16  E-value: 1.64e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  12 GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNeiwQDEKEFLPVQKRK-IGFVFQDYALF 89
Cdd:PRK10247   18 GDAKILN-NISFSLRAGEFKLITGPSGCGKSTLLKIVASLiSPTSGTLLFEG---EDISTLKPEIYRQqVSYCAQTPTLF 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  90 PNmTVLENLFF---VNKDKELANHLLEITELWELKNRL----PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTM 162
Cdd:PRK10247   94 GD-TVYDNLIFpwqIRNQQPDPAIFLDDLERFALPDTIltknIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESN 172

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1441214933 163 RIKLQDEILQLHKEFETTTILVSHDPSEIyKLSNRVIVL 201
Cdd:PRK10247  173 KHNVNEIIHRYVREQNIAVLWVTHDKDEI-NHADKVITL 210
cbiO PRK13646
energy-coupling factor transporter ATPase;
20-237 2.12e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 90.99  E-value: 2.12e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDN-EIWQD--EKEFLPVQKRkIGFVFQ--DYALFPNMT 93
Cdd:PRK13646   25 DVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKpTTGTVTVDDiTITHKtkDKYIRPVRKR-IGMVFQfpESQLFEDTV 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENLF----F---VNKDKELANHLLeiTELWELKNRL---PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:PRK13646  104 EREIIFgpknFkmnLDEVKNYAHRLL--MDLGFSRDVMsqsPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDPQSK 181

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 164 IKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKTSGSAKFSFEgkLLDIIKV 237
Cdd:PRK13646  182 RQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKKKLADWHIG--LPEIVQL 253
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 20-204 2.43e-21

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 93.33  E-value: 2.43e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKV--DNEIWqdekeFLPvQKrkigfvfqdyALFPNMTVLE 96
Cdd:COG4178   381 DLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPyGSGRIARpaGARVL-----FLP-QR----------PYLPLGTLRE 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFVN-----KDKELAnHLLEITELWELKNRL------PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPtmriK 165
Cdd:COG4178   445 ALLYPAtaeafSDAELR-EALEAVGLGHLAERLdeeadwDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALDE----E 519

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1441214933 166 LQDEILQ-LHKEFETTTIL-VSHDPSEIyKLSNRVIVLKDG 204
Cdd:COG4178   520 NEAALYQlLREELPGTTVIsVGHRSTLA-AFHDRVLELTGD 559
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
20-216 2.90e-21

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 90.43  E-value: 2.90e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEIWQD--EKEFlpvqKRKIGFVFQDYALFPNMTVLE 96
Cdd:PRK10253   25 NLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLmTPAHGHVWLDGEHIQHyaSKEV----ARRIGLLAQNATTPGDITVQE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 ----------NLF--FVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:PRK10253  101 lvargryphqPLFtrWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQI 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 165 KLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK10253  181 DLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIV 232
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 20-221 3.17e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 90.20  E-value: 3.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNE-IWQDEKEFLpvqKRKIGFVFQD-YALFPNMTV-- 94
Cdd:PRK13648   27 DVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKsGEIFYNNQaITDDNFEKL---RKHIGIVFQNpDNQFVGSIVky 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 -----LENlFFVNKDK--ELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:PRK13648  104 dvafgLEN-HAVPYDEmhRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLL 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 168 DEILQLHKEFETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGTAKSVLLKTSG 221
Cdd:PRK13648  183 DLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDHAEE 235
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 20-236 4.25e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 90.29  E-value: 4.25e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEIWQDEKEFLPVQKRKIGFVFQ--DYALFpNMTVLE 96
Cdd:PRK13636   24 GININIKKGEVTAILGGNGAGKSTLFQNLNGiLKPSSGRILFDGKPIDYSRKGLMKLRESVGMVFQdpDNQLF-SASVYQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF--VN----KD--KELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:PRK13636  103 DVSFgaVNlklpEDevRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMK 182

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 169 EILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKT----SGSAKFSFEGKLLDIIK 236
Cdd:PRK13636  183 LLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAEKemlrKVNLRLPRIGHLMEILK 254
cbiO TIGR01166
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ...
 20-187 4.54e-21

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130234 [Multi-domain]  Cd Length: 190  Bit Score: 87.86  E-value: 4.54e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDEKEFLPVQKRKIGFVFQ--DYALFpNMTVLE 96
Cdd:TIGR01166  10 GLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQsGAVLIDGEPLDYSRKGLLERRQRVGLVFQdpDDQLF-AADVDQ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF--VN---KDKELANHL---LEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:TIGR01166  89 DVAFgpLNlglSEAEVERRVreaLTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLDPAGREQMLA 168

                         170
                  ....*....|....*....
gi 1441214933 169 EILQLHKEfETTTILVSHD 187
Cdd:TIGR01166 169 ILRRLRAE-GMTVVISTHD 186
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 20-218 4.57e-21

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 92.56  E-value: 4.57e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTL---LRSLAGLEKAQGII-------------------------------KVDNEIW 65
Cdd:TIGR03269  18 NISFTIEEGEVLGILGRSGAGKSVLmhvLRGMDQYEPTSGRIiyhvalcekcgyverpskvgepcpvcggtlePEEVDFW 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  66 Q-DEKEFLPVQKRkIGFVFQ-DYALFPNMTVLENLFFVNKD-----KELANHLLEITELWELKNR---LPNSLSGGQKQR 135
Cdd:TIGR03269  98 NlSDKLRRRIRKR-IAIMLQrTFALYGDDTVLDNVLEALEEigyegKEAVGRAVDLIEMVQLSHRithIARDLSGGEKQR 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 136 VSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:TIGR03269 177 VVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAIWLENGEIKEEGTPDEV 256


                  ...
gi 1441214933 216 LLK 218
Cdd:TIGR03269 257 VAV 259
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
20-219 8.83e-21

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 88.92  E-value: 8.83e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNE-IWQdekeFLPVQ-KRKIGFVFQDYALFPNMTVLE 96
Cdd:PRK11231   20 DLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQsGTVFLGDKpISM----LSSRQlARRLALLPQHHLTPEGITVRE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 ----------NLF--FVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDptmrI 164
Cdd:PRK11231   96 lvaygrspwlSLWgrLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLD----I 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 165 KLQDEILQLHKEFET---TTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV----LLKT 219
Cdd:PRK11231  172 NHQVELMRLMRELNTqgkTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVmtpgLLRT 233
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
9-216 1.91e-20

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 89.19  E-value: 1.91e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   9 ELHGSNG-VMNLD-VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQDeKEFL---PVQKRK----- 78
Cdd:COG4170    12 EIDTPQGrVKAVDrVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNWHVTADRFRWNG-IDLLklsPRERRKiigre 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  79 IGFVFQD--YALFPNMTVLENLFFVNKDKELANH--------------LLE---ITELWELKNRLPNSLSGGQKQRVSLC 139
Cdd:COG4170    91 IAMIFQEpsSCLDPSAKIGDQLIEAIPSWTFKGKwwqrfkwrkkraieLLHrvgIKDHKDIMNSYPHELTEGECQKVMIA 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 140 RALMNRPKLLLMDEPLSALDPTMRI---KLQDEILQLHKefeTTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG4170   171 MAIANQPRLLIADEPTNAMESTTQAqifRLLARLNQLQG---TSILLISHDLESISQWADTITVLYCGQTVESGPTEQIL 247
PLN03211 PLN03211
ABC transporter G-25; Provisional
 29-205 4.65e-20

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 89.94  E-value: 4.65e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  29 DFVALTGLSGSGKTTLLRSLAGleKAQGIIKVDNEIWQDEKEFLPVQKRkIGFVFQDYALFPNMTVLENLFFV------- 101
Cdd:PLN03211   95 EILAVLGPSGSGKSTLLNALAG--RIQGNNFTGTILANNRKPTKQILKR-TGFVTQDDILYPHLTVRETLVFCsllrlpk 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 102 --NKDKELANHLLEITELWELK-------NRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQ 172
Cdd:PLN03211  172 slTKQEKILVAESVISELGLTKcentiigNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGS 251

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1441214933 173 LHKEFETTTILVSHDPSEIYKLSNRVIVLKDGK 205
Cdd:PLN03211  252 LAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGR 284
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 21-188 4.76e-20

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 85.49  E-value: 4.76e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVDNeiwQDEKEFLPVQKRKIGFVFQDYALFPNMTVLENLF 99
Cdd:TIGR01189  19 LSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRpDSGEVRWNG---TPLAEQRDEPHENILYLGHLPGLKPELSALENLH 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 100 FVNKDKELANH----LLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTmRIKLQDEILQLHK 175
Cdd:TIGR01189  96 FWAAIHGGAQRtiedALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKA-GVALLAGLLRAHL 174

                         170
                  ....*....|...
gi 1441214933 176 EFETTTILVSHDP 188
Cdd:TIGR01189 175 ARGGIVLLTTHQD 187
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 20-203 1.29e-19

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 83.36  E-value: 1.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIK--VDNEIWqdekeFLPvQKrkigfvfqdyALFPNMTVLE 96
Cdd:cd03223    19 DLSFEIKPGDRLLITGPSGTGKSSLFRALAGLwPWGSGRIGmpEGEDLL-----FLP-QR----------PYLPLGTLRE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFvnkdkelanhlleiteLWELKnrlpnsLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMriklQDEILQLHKE 176
Cdd:cd03223    83 QLIY----------------PWDDV------LSGGEQQRLAFARLLLHKPKFVFLDEATSALDEES----EDRLYQLLKE 136

                         170       180
                  ....*....|....*....|....*..
gi 1441214933 177 FETTTILVSHDPSeIYKLSNRVIVLKD 203
Cdd:cd03223   137 LGITVISVGHRPS-LWKFHDRVLDLDG 162
NHLM_micro_ABC1 TIGR03796
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...
 20-211 1.54e-19

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274788 [Multi-domain]  Cd Length: 710  Bit Score: 88.08  E-value: 1.54e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEiwqdEKEFLP--VQKRKIGFVFQDYALFPNmTVLE 96
Cdd:TIGR03796 497 NFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLyQPWSGEILFDGI----PREEIPreVLANSVAMVDQDIFLFEG-TVRD 571

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFVN------------KDKELANHLLEI-----TELWE-LKNrlpnsLSGGQKQRVSLCRALMNRPKLLLMDEPLSAL 158
Cdd:TIGR03796 572 NLTLWDptipdadlvracKDAAIHDVITSRpggydAELAEgGAN-----LSGGQRQRLEIARALVRNPSILILDEATSAL 646

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 159 DPTMRIKLQDEIlqlhKEFETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGT 211
Cdd:TIGR03796 647 DPETEKIIDDNL----RRRGCTCIIVAHRLSTI-RDCDEIIVLERGKVVQRGT 694
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 20-207 1.94e-19

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 83.85  E-value: 1.94e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL----EKAQGIIKVDNEiwqDEKEFLPVQKRKIGFVFQDYALFPNMTVL 95
Cdd:cd03233    25 DFSGVVKPGEMVLVLGRPGSGCSTLLKALANRtegnVSVEGDIHYNGI---PYKEFAEKYPGEIIYVSEEDVHFPTLTVR 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLFFVNKDKelanhlleitelwelKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHK 175
Cdd:cd03233   102 ETLDFALRCK---------------GNEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTALEILKCIRTMAD 166

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1441214933 176 EFETTTILVSHDPS-EIYKLSNRVIVLKDGKIV 207
Cdd:cd03233   167 VLKTTTFVSLYQASdEIYDLFDKVLVLYEGRQI 199
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 19-207 2.15e-19

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 84.24  E-value: 2.15e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  19 LDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK---AQGIIKV-DNEIWQDEkeflpvqkrkigfvfqdyalfpnmTV 94
Cdd:COG2401    47 RDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtpVAGCVDVpDNQFGREA------------------------SL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENLFfVNKDKELANHLLEITELWE--LKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQ 172
Cdd:COG2401   103 IDAIG-RKGDFKDAVELLNAVGLSDavLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQK 181

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1441214933 173 LHKEFETTTILVSHDPsEIYK-LSNRVIVLKDGKIV 207
Cdd:COG2401   182 LARRAGITLVVATHHY-DVIDdLQPDLLIFVGYGGV 216
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
20-211 7.32e-19

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 86.17  E-value: 7.32e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLA-GLEKAQGIIKVD-NEIWQDEKEFLpvqKRKIGFVFQDYALFpNMTVLEN 97
Cdd:PRK13657  353 DVSFEAKPGQTVAIVGPTGAGKSTLINLLQrVFDPQSGRILIDgTDIRTVTRASL---RRNIAVVFQDAGLF-NRSIEDN 428

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LfFVNK----DKELANhLLEITELWELKNRLP-----------NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTM 162
Cdd:PRK13657  429 I-RVGRpdatDEEMRA-AAERAQAHDFIERKPdgydtvvgergRQLSGGERQRLAIARALLKDPPILILDEATSALDVET 506

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1441214933 163 RIKLQDEILQLHKefETTTILVSHDPSEIyKLSNRVIVLKDGKIVDDGT 211
Cdd:PRK13657  507 EAKVKAALDELMK--GRTTFIIAHRLSTV-RNADRILVFDNGRVVESGS 552
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
20-191 7.86e-19

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 81.90  E-value: 7.86e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVdneiwqdekeflpVQKRKIGFVFQDYAL---FPnMTVL 95
Cdd:NF040873   10 GVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRpTSGTVRR-------------AGGARVAYVPQRSEVpdsLP-LTVR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 E----NLF--------FVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:NF040873   76 DlvamGRWarrglwrrLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESR 155

                         170       180
                  ....*....|....*....|....*...
gi 1441214933 164 IKLQDEILQLHKEfETTTILVSHDPSEI 191
Cdd:NF040873  156 ERIIALLAEEHAR-GATVVVVTHDLELV 182
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
20-216 1.11e-18

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 83.30  E-value: 1.11e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNE----------------IWQDEKEFLPVQKRkIGFV 82
Cdd:PRK15112   31 PLSFTLREGQTLAIIGENGSGKSTLAKMLAGMiEPTSGELLIDDHplhfgdysyrsqrirmIFQDPSTSLNPRQR-ISQI 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  83 FqDYALFPNmTVLENlffVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTM 162
Cdd:PRK15112  110 L-DFPLRLN-TDLEP---EQREKQIIETLRQVGLLPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSM 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 163 RIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK15112  185 RSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVL 238
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 21-218 1.46e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 83.31  E-value: 1.46e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEiwQDEKEFLPVQKRKIGFVFQ--DYALFpNMTVLEN 97
Cdd:PRK13652   23 INFIAPRNSRIAVIGPNGAGKSTLFRHFNGiLKPTSGSVLIRGE--PITKENIREVRKFVGLVFQnpDDQIF-SPTVEQD 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFF----VNKDKELANH----LLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDE 169
Cdd:PRK13652  100 IAFgpinLGLDEETVAHrvssALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDF 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1441214933 170 ILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLK 218
Cdd:PRK13652  180 LNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQ 228
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 35-187 2.23e-18

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 84.60  E-value: 2.23e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  35 GLSGSGKTTLLRSLAGLEKaqgiiKVDNEIWqdekeflPVQKRKIGFVFQDYALFPNMTVLENLF--------------- 99
Cdd:TIGR03719  38 GLNGAGKSTLLRIMAGVDK-----DFNGEAR-------PQPGIKVGYLPQEPQLDPTKTVRENVEegvaeikdaldrfne 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 100 ----FVNKDKELANHLLEITEL---------WELKN---------RLP------NSLSGGQKQRVSLCRALMNRPKLLLM 151
Cdd:TIGR03719 106 isakYAEPDADFDKLAAEQAELqeiidaadaWDLDSqleiamdalRCPpwdadvTKLSGGERRRVALCRLLLSKPDMLLL 185

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1441214933 152 DEPLSALDPTMRIKLQdeilQLHKEFETTTILVSHD 187
Cdd:TIGR03719 186 DEPTNHLDAESVAWLE----RHLQEYPGTVVAVTHD 217
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 20-210 2.46e-18

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 80.43  E-value: 2.46e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQgiikvDNEIWQDEKEFLPVQK---RKIGFVFQDYALFpNMTVLE 96
Cdd:cd03247    20 NLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQ-----QGEITLDGVPVSDLEKalsSLISVLNQRPYLF-DTTLRN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLffvnkdkelanhlleitelwelknrlPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKe 176
Cdd:cd03247    94 NL--------------------------GRRFSGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQLLSLIFEVLK- 146

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1441214933 177 fETTTILVSHDPSEIYKLsNRVIVLKDGKIVDDG 210
Cdd:cd03247   147 -DKTLIWITHHLTGIEHM-DKILFLENGKIIMQG 178
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
20-215 2.50e-18

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 84.45  E-value: 2.50e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEIWQDEKEFLPVQkRKIGFVFQDYALFPNMTVLENL 98
Cdd:PRK09700   23 SVNLTVYPGEIHALLGENGAGKSTLMKVLSGIhEPTKGTITINNINYNKLDHKLAAQ-LGIGIIYQELSVIDELTVLENL 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF---------------VNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:PRK09700  102 YIgrhltkkvcgvniidWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEV 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 164 IKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK09700  182 DYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDV 232
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
2-210 3.94e-18

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 82.55  E-value: 3.94e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   2 IKIEIKKELHGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEiwqDEKEFLPVQKRKIG 80
Cdd:PRK13537    8 IDFRNVEKRYGDKLVVD-GLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLtHPDAGSISLCGE---PVPSRARHARQRVG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  81 FVFQDYALFPNMTVLENLFFVNK--------DKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMD 152
Cdd:PRK13537   84 VVPQFDNLDPDFTVRENLLVFGRyfglsaaaARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLD 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 153 EPLSALDPTMRiKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:PRK13537  164 EPTTGLDPQAR-HLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEG 220
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
21-219 4.14e-18

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 81.98  E-value: 4.14e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIkvdneIWQDE-----KEFLPVQKRKIGFVFQDyalfPNmtv 94
Cdd:PRK13638   20 LNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQkGAV-----LWQGKpldysKRGLLALRQQVATVFQD----PE--- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 lENLFFVNKDKELANHL-----------------LEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:PRK13638   88 -QQIFYTDIDSDIAFSLrnlgvpeaeitrrvdeaLTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAG 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 158 LDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKT 219
Cdd:PRK13638  167 LDPAGRTQMIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFACT 227
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 20-211 5.36e-18

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 83.72  E-value: 5.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNeiwQDEKEFLPVQKRK-IGFVFQDYALFpNMTVLEN 97
Cdd:COG5265   376 GVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFyDVTSGRILIDG---QDIRDVTQASLRAaIGIVPQDTVLF-NDTIAYN 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFF---------VNKDKELAnHLLE-ITEL---WE-------LKnrlpnsLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:COG5265   452 IAYgrpdaseeeVEAAARAA-QIHDfIESLpdgYDtrvgergLK------LSGGEKQRVAIARTLLKNPPILIFDEATSA 524

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933 158 LDPTMRIKLQDEILQLHKefETTTILVSHdpseiyKLS-----NRVIVLKDGKIVDDGT 211
Cdd:COG5265   525 LDSRTERAIQAALREVAR--GRTTLVIAH------RLStivdaDEILVLEAGRIVERGT 575
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 20-216 7.96e-18

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 82.83  E-value: 7.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKT----TLLRSLAG--LEKAQGIIKVDNE--IWQDEKEFLPVQKRKIGFVFQD--YALF 89
Cdd:PRK15134   27 DVSLQIEAGETLALVGESGSGKSvtalSILRLLPSppVVYPSGDIRFHGEslLHASEQTLRGVRGNKIAMIFQEpmVSLN 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  90 PNMTVLENLFFV-----NKDKELAN----HLLEITELWELKNRL---PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:PRK15134  107 PLHTLEKQLYEVlslhrGMRREAARgeilNCLDRVGIRQAAKRLtdyPHQLSGGERQRVMIAMALLTRPELLIADEPTTA 186

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 158 LDPTmrikLQDEILQLHKEFE----TTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK15134  187 LDVS----VQAQILQLLRELQqelnMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLF 245
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 35-211 1.21e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 81.05  E-value: 1.21e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  35 GLSGSGKTTLLRSLAGLEK-AQGIIKVDN-----EIWQDEKEFLPVQK---------RKIGFVFQ--DYALFPNmTVLEN 97
Cdd:PRK13631   59 GNSGSGKSTLVTHFNGLIKsKYGTIQVGDiyigdKKNNHELITNPYSKkiknfkelrRRVSMVFQfpEYQLFKD-TIEKD 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFF--------VNKDKELANHLLEITEL-WELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQD 168
Cdd:PRK13631  138 IMFgpvalgvkKSEAKKLAKFYLNKMGLdDSYLERSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQ 217

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1441214933 169 EILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:PRK13631  218 LILDAKAN-NKTVFVITHTMEHVLEVADEVIVMDKGKILKTGT 259
hmuV PRK13547
heme ABC transporter ATP-binding protein;
20-233 1.43e-17

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 80.26  E-value: 1.43e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG---LEKAQGIIKVDNEIWQD--------------EKEFLPVQKRKiGFV 82
Cdd:PRK13547   19 DLSLRIEPGRVTALLGRNGAGKSTLLKALAGdltGGGAPRGARVTGDVTLNgeplaaidaprlarLRAVLPQAAQP-AFA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  83 FQDYAL-----FPNMTVLENLffVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRAL---------MNRPKL 148
Cdd:PRK13547   98 FSAREIvllgrYPHARRAGAL--THRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLaqlwpphdaAQPPRY 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 149 LLMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKTSGSAKFSFE 228
Cdd:PRK13547  176 LLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVLTPAHIARCYGFA 255


                  ....*
gi 1441214933 229 GKLLD 233
Cdd:PRK13547  256 VRLVD 260
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
15-208 1.97e-17

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 81.88  E-value: 1.97e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  15 GVMNLD-VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEiwqdekeflPVQKRK--------IGFVFQ 84
Cdd:PRK11288   16 GVKALDdISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDaGSILIDGQ---------EMRFASttaalaagVAIIYQ 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  85 DYALFPNMTVLENLF---------FVNKdKELANHLLEitELWELKNRL-PN----SLSGGQKQRVSLCRALMNRPKLLL 150
Cdd:PRK11288   87 ELHLVPEMTVAENLYlgqlphkggIVNR-RLLNYEARE--QLEHLGVDIdPDtplkYLSIGQRQMVEIAKALARNARVIA 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 151 MDEPLSAL-----DPTMRIklqdeILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVD 208
Cdd:PRK11288  164 FDEPTSSLsareiEQLFRV-----IRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRYVA 220
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 31-199 2.49e-17

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 78.38  E-value: 2.49e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  31 VALTGLSGSGKTTLLRSLAGL-EKAQGIIKvdneiWQDEKEFLPVQKRKIGFVFQDYALFPNMTVLENL-F---FVNKDK 105
Cdd:PRK13539   31 LVLTGPNGSGKTTLLRLIAGLlPPAAGTIK-----LDGGDIDDPDVAEACHYLGHRNAMKPALTVAENLeFwaaFLGGEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 106 ELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALM-NRPkLLLMDEPLSALDPTMrIKLQDEILQLHKEFETTTILV 184
Cdd:PRK13539  106 LDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVsNRP-IWILDEPTAALDAAA-VALFAELIRAHLAQGGIVIAA 183

                         170
                  ....*....|....*
gi 1441214933 185 SHDPSEIYklSNRVI 199
Cdd:PRK13539  184 THIPLGLP--GAREL 196
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
11-210 2.75e-17

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 80.26  E-value: 2.75e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  11 HGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIwqdekefLPVQKR----KIGFVFQD 85
Cdd:PRK13536   51 YGDKAVVN-GLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPdAGKITVLGVP-------VPARARlaraRIGVVPQF 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  86 YALFPNMTVLENL-----FFVNKDKELAN---HLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:PRK13536  123 DNLDLEFTVRENLlvfgrYFGMSTREIEAvipSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTG 202

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 158 LDPTMRiKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDG 210
Cdd:PRK13536  203 LDPHAR-HLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEG 254
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 10-215 3.82e-17

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 80.84  E-value: 3.82e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  10 LHGSNGVMNL-DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDekefLPVQKR---KIGFVFQ 84
Cdd:COG3845   265 VRDDRGVPALkDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPAsGSIRLDGEDITG----LSPRERrrlGVAYIPE 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  85 D---YALFPNMTVLENL-------------FFVNKDK--ELANHLLEitelwELKNRLPN------SLSGGQKQRVSLCR 140
Cdd:COG3845   341 DrlgRGLVPDMSVAENLilgryrrppfsrgGFLDRKAirAFAEELIE-----EFDVRTPGpdtparSLSGGNQQKVILAR 415

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 141 ALMNRPKLLLMDEPLSALDP--TMRIklQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:COG3845   416 ELSRDPKLLIAAQPTRGLDVgaIEFI--HQRLLELRDA-GAAVLLISEDLDEILALSDRIAVMYEGRIVGEVPAAEA 489
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 31-215 5.15e-17

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 79.40  E-value: 5.15e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  31 VALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIW--QDEKEFLPVQKRKI-----GFVFQDyalfpNMTVLENLFFV-- 101
Cdd:PRK11022   36 VGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEFngQDLQRISEKERRNLvgaevAMIFQD-----PMTSLNPCYTVgf 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 102 ------------NKD--KELANHLLEITELWELKNRL---PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:PRK11022  111 qimeaikvhqggNKKtrRQRAIDLLNQVGIPDPASRLdvyPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQA 190

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 165 KLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK11022  191 QIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDI 241
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
20-216 7.67e-17

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 80.06  E-value: 7.67e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLlrslAGL-----EKAQGIIKVDNEIWQDEKefLPVQKRKIGFVFQDYALFpNMTV 94
Cdd:PRK11176  361 NINFKIPAGKTVALVGRSGSGKSTI----ANLltrfyDIDEGEILLDGHDLRDYT--LASLRNQVALVSQNVHLF-NDTI 433

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENLFFVNKDK---ELANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP 160
Cdd:PRK11176  434 ANNIAYARTEQysrEQIEEAARMAYAMDFINKMDNgldtvigengvLLSGGQRQRIAIARALLRDSPILILDEATSALDT 513

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 161 TMRIKLQDEILQLHKefETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK11176  514 ESERAIQAALDELQK--NRTSLVIAHRLSTIEK-ADEILVVEDGEIVERGTHAELL 566
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 20-208 8.07e-17

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 79.94  E-value: 8.07e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKvdneiWQDekeflpvqKRKIGFVFQDYAL-FPN-MTVLE 96
Cdd:PRK15064  337 NLNLLLEAGERLAIIGENGVGKTTLLRTLVGeLEPDSGTVK-----WSE--------NANIGYYAQDHAYdFENdLTLFD 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 --NLFFVNKDKELA-----NHLL----EItelwelkNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDptMR-I 164
Cdd:PRK15064  404 wmSQWRQEGDDEQAvrgtlGRLLfsqdDI-------KKSVKVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMD--MEsI 474

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1441214933 165 klqdEILQLH-KEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVD 208
Cdd:PRK15064  475 ----ESLNMAlEKYEGTLIFVSHDREFVSSLATRIIEITPDGVVD 515
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 20-215 8.52e-17

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 79.90  E-value: 8.52e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKT-TLLRSLAGLEKAQGIIKVDNEIW------------QDEKEFLPVQKRKIGFVFQD- 85
Cdd:PRK10261   34 NLSFSLQRGETLAIVGESGSGKSvTALALMRLLEQAGGLVQCDKMLLrrrsrqvielseQSAAQMRHVRGADMAMIFQEp 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  86 -YALFPNMTVLENLF-------FVNKDKEL--ANHLLE---ITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMD 152
Cdd:PRK10261  114 mTSLNPVFTVGEQIAesirlhqGASREEAMveAKRMLDqvrIPEAQTILSRYPHQLSGGMRQRVMIAMALSCRPAVLIAD 193

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 153 EPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK10261  194 EPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQI 256
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 20-230 1.27e-16

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 79.12  E-value: 1.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEiwqdekeflPVQKRKIGFVFQDYALFPNMTVLENL 98
Cdd:PRK09536   21 GVDLSVREGSLVGLVGPNGAGKTTLLRAINGtLTPTAGTVLVAGD---------DVEALSARAASRRVASVPQDTSLSFE 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFVNKDKELANH-------------------LLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALD 159
Cdd:PRK09536   92 FDVRQVVEMGRTphrsrfdtwtetdraaverAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLD 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 160 ptmrIKLQDEILQLHKEF---ETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLlkTSGSAKFSFEGK 230
Cdd:PRK09536  172 ----INHQVRTLELVRRLvddGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVL--TADTLRAAFDAR 239
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 12-187 1.47e-16

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 77.08  E-value: 1.47e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  12 GSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDneiwqdekeflpvQKRKIGFVFQDYALFP 90
Cdd:PRK09544   15 GQRRVLS-DVSLELKPGKILTLLGPNGAGKSTLVRVVLGLvAPDEGVIKRN-------------GKLRIGYVPQKLYLDT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLENLFF-----VNKDKEL-------ANHLLEITElwelknrlpNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSAL 158
Cdd:PRK09544   81 TLPLTVNRFLrlrpgTKKEDILpalkrvqAGHLIDAPM---------QKLSGGETQRVLLARALLNRPQLLVLDEPTQGV 151

                         170       180
                  ....*....|....*....|....*....
gi 1441214933 159 DPTMRIKLQDEILQLHKEFETTTILVSHD 187
Cdd:PRK09544  152 DVNGQVALYDLIDQLRRELDCAVLMVSHD 180
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
20-216 1.57e-16

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 79.38  E-value: 1.57e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEiwqdekeflPVQ-------KRKIGFVFQDyalfPn 91
Cdd:PRK10790  359 NINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTeGEIRLDGR---------PLSslshsvlRQGVAMVQQD----P- 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 mTVLENLFFVNK------DKELANHLLEITELWELKNRLP-----------NSLSGGQKQRVSLCRALMNRPKLLLMDEP 154
Cdd:PRK10790  425 -VVLADTFLANVtlgrdiSEEQVWQALETVQLAELARSLPdglytplgeqgNNLSVGQKQLLALARVLVQTPQILILDEA 503

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 155 LSALDPTMRIKLQdEILQLHKEfETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK10790  504 TANIDSGTEQAIQ-QALAAVRE-HTTLVVIAHRLSTIVE-ADTILVLHRGQAVEQGTHQQLL 562
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 20-212 2.12e-16

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 76.64  E-value: 2.12e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK---AQGIIKVDNEiwqDEKEfLPVQKRK---IGFVFQDYALFPNMT 93
Cdd:COG0396    18 GVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKyevTSGSILLDGE---DILE-LSPDERAragIFLAFQYPVEIPGVS 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 V---------------LENLFFVNKDKELANhLLEITElwELKNR-LPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:COG0396    94 VsnflrtalnarrgeeLSAREFLKLLKEKMK-ELGLDE--DFLDRyVNEGFSGGEKKRNEILQMLLLEPKLAILDETDSG 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 158 LD-PTMRIkLQDEILQLHKEfETTTILVSHDPsEI--YKLSNRVIVLKDGKIVDDGTA 212
Cdd:COG0396   171 LDiDALRI-VAEGVNKLRSP-DRGILIITHYQ-RIldYIKPDFVHVLVDGRIVKSGGK 225
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 20-213 2.22e-16

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 79.00  E-value: 2.22e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNE-IWQDEKEFLpvqKRKIGFVFQDYALFpNMTVLEN 97
Cdd:TIGR00958 499 GLTFTLHPGEVVALVGPSGSGKSTVAALLQNLyQPTGGQVLLDGVpLVQYDHHYL---HRQVALVGQEPVLF-SGSVREN 574

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNKDKELAnhllEITELWELKN------RLPNS-----------LSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP 160
Cdd:TIGR00958 575 IAYGLTDTPDE----EIMAAAKAANahdfimEFPNGydtevgekgsqLSGGQKQRIAIARALVRKPRVLILDEATSALDA 650

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 161 TMRIKLQdeilQLHKEFETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGTAK 213
Cdd:TIGR00958 651 ECEQLLQ----ESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHK 698
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 20-210 4.92e-16

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 74.49  E-value: 4.92e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK---AQGIIKVDNEiwqDEKEfLPVQKRK---IGFVFQDYALFPNMT 93
Cdd:cd03217    18 GVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKyevTEGEILFKGE---DITD-LPPEERArlgIFLAFQYPPEIPGVK 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENLFFVNKdkelanhlleitelwelknrlpnSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDpTMRIKLQDEILQL 173
Cdd:cd03217    94 NADFLRYVNE-----------------------GFSGGEKKRNEILQLLLLEPDLAILDEPDSGLD-IDALRLVAEVINK 149

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1441214933 174 HKEFETTTILVSHDPsEI--YKLSNRVIVLKDGKIVDDG 210
Cdd:cd03217   150 LREEGKSVLIITHYQ-RLldYIKPDRVHVLYDGRIVKSG 187
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 33-186 1.04e-15

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 73.83  E-value: 1.04e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  33 LTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNeiwQDEKEFLPVQKRKIGFVFQDYALFPNMTVLENLFFvnkDKELANHL 111
Cdd:PRK13540   32 LKGSNGAGKTTLLKLIAGLLNPEkGEILFER---QSIKKDLCTYQKQLCFVGHRSGINPYLTLRENCLY---DIHFSPGA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 112 LEITEL---WELKNRLP---NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEIlQLHKEFETTTILVS 185
Cdd:PRK13540  106 VGITELcrlFSLEHLIDypcGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKI-QEHRAKGGAVLLTS 184


                  .
gi 1441214933 186 H 186
Cdd:PRK13540  185 H 185
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 15-207 1.33e-15

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 76.24  E-value: 1.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  15 GVMNLD-VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNeiwQDEKEFLPVQKRKIG--FVFQDYALFP 90
Cdd:PRK15439   23 GVEVLKgIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDsGTLEIGG---NPCARLTPAKAHQLGiyLVPQEPLLFP 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLEN-LFFVNKDKELANHLLEIteLWELKNRLPNSLSGG-----QKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:PRK15439  100 NLSVKENiLFGLPKRQASMQKMKQL--LAALGCQLDLDSSAGslevaDRQIVEILRGLMRDSRILILDEPTASLTPAETE 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1441214933 165 KLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIV 207
Cdd:PRK15439  178 RLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDGTIA 219
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 15-207 1.36e-15

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 76.40  E-value: 1.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  15 GVMNLD-VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQgiiKVDNEIWQDEKEFLP-----VQKRKIGFVFQDYAL 88
Cdd:TIGR02633  13 GVKALDgIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHG---TWDGEIYWSGSPLKAsnirdTERAGIVIIHQELTL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  89 FPNMTVLENLFFVNK---------DKEL---ANHLLEITELWELKNRLPNS-LSGGQKQRVSLCRALMNRPKLLLMDEPL 155
Cdd:TIGR02633  90 VPELSVAENIFLGNEitlpggrmaYNAMylrAKNLLRELQLDADNVTRPVGdYGGGQQQLVEIAKALNKQARLLILDEPS 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 156 SALDPTMRIKLQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIV 207
Cdd:TIGR02633 170 SSLTEKETEILLDIIRDL-KAHGVACVYISHKLNEVKAVCDTICVIRDGQHV 220
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 24-234 1.97e-15

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 73.98  E-value: 1.97e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  24 DIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGiikVDNEIWQDEKEFLPvQKRKIGFvfqdyalfpNMTVLENLFFVNK 103
Cdd:cd03237    21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDE---GDIEIELDTVSYKP-QYIKADY---------EGTVRDLLSSITK 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 104 DK--------ELANHLleitELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHK 175
Cdd:cd03237    88 DFythpyfktEIAKPL----QIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFAE 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933 176 EFETTTILVSHDPSEIYKLSNRVIVLkDGKIVDDGTAKSVLLKTSGSAKFSfegKLLDI 234
Cdd:cd03237   164 NNEKTAFVVEHDIIMIDYLADRLIVF-EGEPSVNGVANPPQSLRSGMNRFL---KNLDI 218
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 20-206 1.98e-15

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 73.66  E-value: 1.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNE-IWQDEKEFLpvqKRKIGFVFQDYALFPNmTVLEN 97
Cdd:cd03248    32 DVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQgGQVLLDGKpISQYEHKYL---HSKVSLVGQEPVLFAR-SLQDN 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNKDKEL---------ANHLLEITEL----WELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:cd03248   108 IAYGLQSCSFecvkeaaqkAHAHSFISELasgyDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQ 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1441214933 165 KLQDEILQLHKefETTTILVSHDPSEIYKlSNRVIVLKDGKI 206
Cdd:cd03248   188 QVQQALYDWPE--RRTVLVIAHRLSTVER-ADQILVLDGGRI 226
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 20-206 2.72e-15

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 75.47  E-value: 2.72e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGiikvdNEIWQDEKEFL---PVQKRKIGFVF-----QDYALF-- 89
Cdd:PRK15439  281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARG-----GRIMLNGKEINalsTAQRLARGLVYlpedrQSSGLYld 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  90 -------PNMTVLENLFFVNKDKELA-----NHLLEITelWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:PRK15439  356 aplawnvCALTHNRRGFWIKPARENAvleryRRALNIK--FNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRG 433

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1441214933 158 LDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:PRK15439  434 VDVSARNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGEI 481
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 20-211 5.19e-15

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 72.06  E-value: 5.19e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSL-AGLEKAQGIIKVDNeiwQDEKEfLPVQK--RKIGFVFQDYALFPNmTVLE 96
Cdd:cd03369    26 NVSFKVKAGEKIGIVGRTGAGKSTLILALfRFLEAEEGKIEIDG---IDIST-IPLEDlrSSLTIIPQDPTLFSG-TIRS 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFFVNK--DKELANhLLEITELwelknrlPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEIlqlH 174
Cdd:cd03369   101 NLDPFDEysDEEIYG-ALRVSEG-------GLNLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTI---R 169

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1441214933 175 KEFETTTIL-VSHDPSEIYKLsNRVIVLKDGKIVDDGT 211
Cdd:cd03369   170 EEFTNSTILtIAHRLRTIIDY-DKILVMDAGEVKEYDH 206
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 20-204 5.88e-15

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 71.51  E-value: 5.88e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGlEKAQGIIKvdNEIWQDEKEFLPVQKRKIGFVFQDYALFPNMTVLENLF 99
Cdd:cd03232    25 NISGYVKPGTLTALMGESGAGKTTLLDVLAG-RKTAGVIT--GEILINGRPLDKNFQRSTGYVEQQDVHSPNLTVREALR 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 100 FvnkdkelanhlleitelwELKNRlpnSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP-----TMRI--KLQDEILq 172
Cdd:cd03232   102 F------------------SALLR---GLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSqaaynIVRFlkKLADSGQ- 159

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1441214933 173 lhkefettTILVS-HDPSE-IYKLSNRVIVLKDG 204
Cdd:cd03232   160 --------AILCTiHQPSAsIFEKFDRLLLLKRG 185
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 8-206 6.74e-15

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 74.27  E-value: 6.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   8 KELHGSnGVMNldVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEiwqdekeflPVQKRK-------- 78
Cdd:PRK10762  261 DNLSGP-GVND--VSFTLRKGEILGVSGLMGAGRTELMKVLYGaLPRTSGYVTLDGH---------EVVTRSpqdglang 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  79 IGFVFQDY---ALFPNMTVLENL------FFVNKDKELaNHLLE---ITELWELKN-RLPN------SLSGGQKQRVSLC 139
Cdd:PRK10762  329 IVYISEDRkrdGLVLGMSVKENMsltalrYFSRAGGSL-KHADEqqaVSDFIRLFNiKTPSmeqaigLLSGGNQQKVAIA 407

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 140 RALMNRPKLLLMDEPLSALDptmrIKLQDEILQLHKEFET---TTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:PRK10762  408 RGLMTRPKVLILDEPTRGVD----VGAKKEIYQLINQFKAeglSIILVSSEMPEVLGMSDRILVMHEGRI 473
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 31-201 6.86e-15

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 71.37  E-value: 6.86e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  31 VALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNeiwQDEKEFLPVQKRKIGFVFQDYALFPNMTVLENLFFVNKD--KEL 107
Cdd:cd03231    29 LQVTGPNGSGKTTLLRILAGLsPPLAGRVLLNG---GPLDFQRDSIARGLLYLGHAPGIKTTLSVLENLRFWHADhsDEQ 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 108 ANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQlHKEFETTTILVSHD 187
Cdd:cd03231   106 VEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAG-HCARGGMVVLTTHQ 184

                         170
                  ....*....|....
gi 1441214933 188 PSEIYKLSNRVIVL 201
Cdd:cd03231   185 DLGLSEAGARELDL 198
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 21-216 9.32e-15

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 72.18  E-value: 9.32e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNeiwQDEKEF-LPVQKRKIGFVFQDYALFPNMTVLENLF 99
Cdd:COG4138    15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGLLPGQGEILLNG---RPLSDWsAAELARHRAYLSQQQSPPFAMPVFQYLA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 100 F----VNKDKELANHLLEITELWELKNRLP---NSLSGGQKQRVSLCRALMN-------RPKLLLMDEPLSALDPTMRIK 165
Cdd:COG4138    92 LhqpaGASSEAVEQLLAQLAEALGLEDKLSrplTQLSGGEWQRVRLAAVLLQvwptinpEGQLLLLDEPMNSLDVAQQAA 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 166 LqdeiLQLHKEFET---TTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:COG4138   172 L----DRLLRELCQqgiTVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVM 221
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 21-216 1.25e-14

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 71.50  E-value: 1.25e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDN---EIWQdekefLPVQKRKIGFVFQDYALFPNMTVLEN 97
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLLPGSGSIQFAGqplEAWS-----AAELARHRAYLSQQQTPPFAMPVFQY 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNKDK----ELANHLLEITELWELKNRLP---NSLSGGQKQRVSLCRALM-----NRP--KLLLMDEPLSALDPTmr 163
Cdd:PRK03695   90 LTLHQPDKtrteAVASALNEVAEALGLDDKLGrsvNQLSGGEWQRVRLAAVVLqvwpdINPagQLLLLDEPMNSLDVA-- 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 164 iklQDEIL-QLHKEFETTTILV---SHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK03695  168 ---QQAALdRLLSELCQQGIAVvmsSHDLNHTLRHADRVWLLKQGKLLASGRRDEVL 221
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
20-159 1.46e-14

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 70.60  E-value: 1.46e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKvdneiWQDEkeflPVqkRKIGFVFQDYALF--------P 90
Cdd:PRK13538   19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLaRPDAGEVL-----WQGE----PI--RRQRDEYHQDLLYlghqpgikT 87

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933  91 NMTVLENLFFVNKdkelANHLLEITELWE------LKNR--LP-NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALD 159
Cdd:PRK13538   88 ELTALENLRFYQR----LHGPGDDEALWEalaqvgLAGFedVPvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAID 161
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
35-186 1.54e-14

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 70.65  E-value: 1.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  35 GLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDEKeflpvQKRKIGFVFQDYALFPNMTVLENLFFVN-----KDKELA 108
Cdd:PRK13543   44 GDNGAGKTTLLRVLAGLLHVEsGQIQIDGKTATRGD-----RSRFMAYLGHLPGLKADLSTLENLHFLCglhgrRAKQMP 118

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 109 NHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTmRIKLQDEILQLHKEFETTTILVSH 186
Cdd:PRK13543  119 GSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLE-GITLVNRMISAHLRGGGAALVTTH 195
COG4674 COG4674
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 20-215 1.68e-14

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443710 [Multi-domain]  Cd Length: 250  Bit Score: 71.30  E-value: 1.68e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQG--IIKVDNEIWQ-DEKEflpVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:COG4674    28 DLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSgsVLFGGTDLTGlDEHE---IARLGIGRKFQKPTVFEELTVFE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NL--------------FFVNKDKELA--NHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP 160
Cdd:COG4674   105 NLelalkgdrgvfaslFARLTAEERDriEEVLETIGLTDKADRLAGLLSHGQKQWLEIGMLLAQDPKLLLLDEPVAGMTD 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 161 TMRIKLQDEILQLHKefETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:COG4674   185 AETERTAELLKSLAG--KHSVVVVEHDMEFVRQIARKVTVLHQGSVLAEGSLDEV 237
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
32-216 1.97e-14

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 71.36  E-value: 1.97e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  32 ALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEI---WqDEKEFlpvqKRKIGFVFQDYALFPNMTVLENLF-------- 99
Cdd:PRK10575   41 GLIGHNGSGKSTLLKMLGRHQPPsEGEILLDAQPlesW-SSKAF----ARKVAYLPQQLPAAEGMTVRELVAigrypwhg 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 100 ----FVNKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHK 175
Cdd:PRK10575  116 algrFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQ 195

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1441214933 176 EFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK10575  196 ERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELM 236
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 21-211 3.68e-14

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 72.74  E-value: 3.68e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNeiwQDEKEFLPVQKRKIGFVFQDYALFPNMTVLENLF 99
Cdd:TIGR01257  949 LNITFYENQITAFLGHNGAGKTTTLSILTGLlPPTSGTVLVGG---KDIETNLDAVRQSLGMCPQHNILFHHLTVAEHIL 1025

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  100 FV----NKDKELAN----HLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEIL 171
Cdd:TIGR01257 1026 FYaqlkGRSWEEAQlemeAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLL 1105

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1441214933  172 QLHKefETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:TIGR01257 1106 KYRS--GRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGT 1143
GguA NF040905
sugar ABC transporter ATP-binding protein;
15-208 4.41e-14

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 71.74  E-value: 4.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  15 GVMNL-DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA---QGIIKVDNEiwqdEKEFLPV---QKRKIGFVFQDYA 87
Cdd:NF040905   13 GVKALdDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHgsyEGEILFDGE----VCRFKDIrdsEALGIVIIHQELA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  88 LFPNMTVLENLFFVNK-------DKELANH----LLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:NF040905   89 LIPYLSIAENIFLGNErakrgviDWNETNRrareLLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDEPTA 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 157 ALDPTMRIKLQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVD 208
Cdd:NF040905  169 ALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVLRDGRTIE 219
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 14-205 4.81e-14

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 71.88  E-value: 4.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  14 NGVMNLD-VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA---QGIIKVDNEiwqdEKEFLPV---QKRKIGFVFQDY 86
Cdd:PRK13549   16 GGVKALDnVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHgtyEGEIIFEGE----ELQASNIrdtERAGIAIIHQEL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  87 ALFPNMTVLENLFFVNkdkEL-ANHLLEITELW----ELKNRL-----PNS----LSGGQKQRVSLCRALMNRPKLLLMD 152
Cdd:PRK13549   92 ALVKELSVLENIFLGN---EItPGGIMDYDAMYlraqKLLAQLkldinPATpvgnLGLGQQQLVEIAKALNKQARLLILD 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 153 EPLSAL-DPTMRIKLqdEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGK 205
Cdd:PRK13549  169 EPTASLtESETAVLL--DIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGR 220
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 9-234 7.00e-14

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 71.20  E-value: 7.00e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   9 ELHGSNGV--------MNLDvNLDIRSKDFVALTGLSGSGKTTLLRSLAG--------------------LEKAQGIIkv 60
Cdd:PRK10938    3 SLQISQGTfrlsdtktLQLP-SLTLNAGDSWAFVGANGSGKSALARALAGelpllsgerqsqfshitrlsFEQLQKLV-- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  61 dNEIWQ---------DEKEFlpvqKRKIGFVFQDYAlfpnmtvlenlffvnKDKELANHLLEITELWELKNRLPNSLSGG 131
Cdd:PRK10938   80 -SDEWQrnntdmlspGEDDT----GRTTAEIIQDEV---------------KDPARCEQLAQQFGITALLDRRFKYLSTG 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 132 QKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:PRK10938  140 ETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLHQS-GITLVLVLNRFDEIPDFVQFAGVLADCTLAETGE 218

                         250       260
                  ....*....|....*....|...
gi 1441214933 212 aKSVLLKTSGSAKFSFEGKLLDI 234
Cdd:PRK10938  219 -REEILQQALVAQLAHSEQLEGV 240
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 35-187 7.76e-14

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 71.30  E-value: 7.76e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  35 GLSGSGKTTLLRSLAGlekaqgiikVDNEIwqdEKEFLPVQKRKIGFVFQDYALFPNMTVLENLFF-VNKDKELANHLLE 113
Cdd:PRK11819   40 GLNGAGKSTLLRIMAG---------VDKEF---EGEARPAPGIKVGYLPQEPQLDPEKTVRENVEEgVAEVKAALDRFNE 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 114 ITE---------------------------LWELKN---------RLP------NSLSGGQKQRVSLCRALMNRPKLLLM 151
Cdd:PRK11819  108 IYAayaepdadfdalaaeqgelqeiidaadAWDLDSqleiamdalRCPpwdakvTKLSGGERRRVALCRLLLEKPDMLLL 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1441214933 152 DEPLSALDPtmriklqdEI---LQLH-KEFETTTILVSHD 187
Cdd:PRK11819  188 DEPTNHLDA--------ESvawLEQFlHDYPGTVVAVTHD 219
PTZ00243 PTZ00243
ABC transporter; Provisional
 20-230 1.91e-13

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 70.58  E-value: 1.91e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGiikvdnEIWQDekeflpvqkRKIGFVFQDyALFPNMTVLEN- 97
Cdd:PTZ00243   678 DVSVSVPRGKLTVVLGATGSGKSTLLQSLLSqFEISEG------RVWAE---------RSIAYVPQQ-AWIMNATVRGNi 741

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   98 LFFvnkDKELANHLLEITELWELKNRLPN--------------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTM- 162
Cdd:PTZ00243   742 LFF---DEEDAARLADAVRVSQLEADLAQlgggleteigekgvNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVg 818

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  163 -RIkLQDEIL-QLHKEfetTTILVSHDpSEIYKLSNRVIVLKDGKIVDDGTAKSvLLKTSGSAKFSFEGK 230
Cdd:PTZ00243   819 eRV-VEECFLgALAGK---TRVLATHQ-VHVVPRADYVVALGDGRVEFSGSSAD-FMRTSLYATLAAELK 882
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 20-216 2.33e-13

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 70.14  E-value: 2.33e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGlEKAQGIIKVDNEIWQD---EKEFLPVQKRKIGFVFQDYALFPNMTVLE 96
Cdd:TIGR00956   79 PMDGLIKPGELTVVLGRPGSGCSTLLKTIAS-NTDGFHIGVEGVITYDgitPEEIKKHYRGDVVYNAETDVHFPHLTVGE 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   97 NLFFVNK------------DKELANHL---------LEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPL 155
Cdd:TIGR00956  158 TLDFAARcktpqnrpdgvsREEYAKHIadvymatygLSHTRNTKVGNDFVRGVSGGERKRVSIAEASLGGAKIQCWDNAT 237

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933  156 SALDPTMRIKLQdEILQLHKEFETTTILVS-HDPSE-IYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:TIGR00956  238 RGLDSATALEFI-RALKTSANILDTTPLVAiYQCSQdAYELFDKVIVLYEGYQIYFGPADKAK 299
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 82-203 2.65e-13

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 70.06  E-value: 2.65e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   82 VFQDYALFpNMTVLENLFFVNKD--KELANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKL 148
Cdd:PTZ00265  1301 VSQEPMLF-NMSIYENIKFGKEDatREDVKRACKFAAIDEFIESLPNkydtnvgpygkSLSGGQKQRIAIARALLREPKI 1379

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933  149 LLMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIyKLSNRVIVLKD 203
Cdd:PTZ00265  1380 LLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASI-KRSDKIVVFNN 1433
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 20-216 6.52e-13

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 68.31  E-value: 6.52e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLA-GLEKAQGIIKVDNeiwQDEKEFLPVQKRK-IGFVFQDYALFpNMTVLEN 97
Cdd:PRK11160  358 GLSLQIKAGEKVALLGRTGCGKSTLLQLLTrAWDPQQGEILLNG---QPIADYSEAALRQaISVVSQRVHLF-SATLRDN 433

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 LFFVNKDkelAN--HLLEITELWELKNRLPNS-------------LSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP-T 161
Cdd:PRK11160  434 LLLAAPN---ASdeALIEVLQQVGLEKLLEDDkglnawlgeggrqLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAeT 510

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 162 MRiklqdEILQLHKEF--ETTTILVSHDPSEIYKLsNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK11160  511 ER-----QILELLAEHaqNKTVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQELL 561
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
96-221 8.26e-13

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 67.45  E-value: 8.26e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLFFVNKDKEL--------ANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:NF000106  105 ENLYMIGR*LDLsrkdararADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVW 184

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 168 DEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLKTSG 221
Cdd:NF000106  185 DEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVGG 237
PLN03232 PLN03232
ABC transporter C family member; Provisional
 20-211 8.50e-13

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 68.46  E-value: 8.50e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGlekaqgiikvdnEIWQDEKEFLpVQKRKIGFVFQDYALFpNMTVLENLF 99
Cdd:PLN03232   635 DINLEIPVGSLVAIVGGTGEGKTSLISAMLG------------ELSHAETSSV-VIRGSVAYVPQVSWIF-NATVRENIL 700

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  100 FVNK----------DKELANHLLEI---TELWELKNRLPNsLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKL 166
Cdd:PLN03232   701 FGSDfeserywraiDVTALQHDLDLlpgRDLTEIGERGVN-ISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQV 779

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1441214933  167 QDEILQlHKEFETTTILVSHDpSEIYKLSNRVIVLKDGKIVDDGT 211
Cdd:PLN03232   780 FDSCMK-DELKGKTRVLVTNQ-LHFLPLMDRIILVSEGMIKEEGT 822
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 21-206 1.02e-12

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 67.69  E-value: 1.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDEKeflPVQKRK-IGFVFQDYALFPNMTVLENL 98
Cdd:PRK10522  342 INLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQsGEILLDGKPVTAEQ---PEDYRKlFSAVFTDFHLFDQLLGPEGK 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 ffvNKDKELANHLLEITEL---WELK-NRLPN-SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQL 173
Cdd:PRK10522  419 ---PANPALVEKWLERLKMahkLELEdGRISNlKLSKGQKKRLALLLALAEERDILLLDEWAADQDPHFRREFYQVLLPL 495

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1441214933 174 HKEFETTTILVSHDPSeIYKLSNRVIVLKDGKI 206
Cdd:PRK10522  496 LQEMGKTIFAISHDDH-YFIHADRLLEMRNGQL 527
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
21-216 1.07e-12

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 67.13  E-value: 1.07e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVD----NEIwqDEKEFLPVQKRK-----IGFVFQD--YALF 89
Cdd:PRK15093   26 VSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADrmrfDDI--DLLRLSPRERRKlvghnVSMIFQEpqSCLD 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  90 PNMTVLENLF--------------FVNKDKELANHLLE---ITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMD 152
Cdd:PRK15093  104 PSERVGRQLMqnipgwtykgrwwqRFGWRKRRAIELLHrvgIKDHKDAMRSFPYELTEGECQKVMIAIALANQPRLLIAD 183

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 153 EPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PRK15093  184 EPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELV 247
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 20-204 1.08e-12

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 65.82  E-value: 1.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEIwQDEKEFLPVQKRK---IGFVFQDYALFpNMTVL 95
Cdd:cd03290    19 NINIRIPTGQLTMIVGQVGCGKSSLLLAILGeMQTLEGKVHWSNKN-ESEPSFEATRSRNrysVAYAAQKPWLL-NATVE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 ENLFF---VNKDKELAN----------HLLEITELWELKNRLPNsLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTM 162
Cdd:cd03290    97 ENITFgspFNKQRYKAVtdacslqpdiDLLPFGDQTEIGERGIN-LSGGQRQRICVARALYQNTNIVFLDDPFSALDIHL 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1441214933 163 RIKL-QDEILQLHKEFETTTILVSHDPSEIYKlSNRVIVLKDG 204
Cdd:cd03290   176 SDHLmQEGILKFLQDDKRTLVLVTHKLQYLPH-ADWIIAMKDG 217
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 30-225 1.66e-12

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 67.66  E-value: 1.66e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   30 FVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEIwqdekEFLPVQkrkigfvfqdyALFPNMTVLENLFFVNKDKE-L 107
Cdd:TIGR00957  666 LVAVVGQVGCGKSSLLSALLAeMDKVEGHVHMKGSV-----AYVPQQ-----------AWIQNDSLRENILFGKALNEkY 729

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  108 ANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKE 176
Cdd:TIGR00957  730 YQQVLEACALLPDLEILPSgdrteigekgvNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFEHVIGPEGV 809

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1441214933  177 FETTT-ILVSHDPSEIYKLsNRVIVLKDGKIVDDGTAKSVLLKTSGSAKF 225
Cdd:TIGR00957  810 LKNKTrILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQRDGAFAEF 858
PLN03130 PLN03130
ABC transporter C family member; Provisional
 20-211 3.29e-12

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 66.69  E-value: 3.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG----LEKAQGIIKvdneiwqdekeflpvqkRKIGFVFQDYALFpNMTVL 95
Cdd:PLN03130   635 NINLDVPVGSLVAIVGSTGEGKTSLISAMLGelppRSDASVVIR-----------------GTVAYVPQVSWIF-NATVR 696

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   96 EN-LFFVNKDKELANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMR 163
Cdd:PLN03130   697 DNiLFGSPFDPERYERAIDVTALQHDLDLLPGgdlteigergvNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVG 776

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1441214933  164 IKLQDEILQlhKEFETTT-ILVShdpSEIYKLS--NRVIVLKDGKIVDDGT 211
Cdd:PLN03130   777 RQVFDKCIK--DELRGKTrVLVT---NQLHFLSqvDRIILVHEGMIKEEGT 822
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 31-207 3.39e-12

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 66.51  E-value: 3.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  31 VALTGLSGSGKTTLLRSLAGlekaqgiikvdnEIWQDEKEFLPVQKRKIGFVFQDyalfPNMTVLENLF-FVNKD-KELA 108
Cdd:PRK11147   32 VCLVGRNGAGKSTLMKILNG------------EVLLDDGRIIYEQDLIVARLQQD----PPRNVEGTVYdFVAEGiEEQA 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 109 NHL----------------------------LEITELWELKNRLP--------------NSLSGGQKQRVSLCRALMNRP 146
Cdd:PRK11147   96 EYLkryhdishlvetdpseknlnelaklqeqLDHHNLWQLENRINevlaqlgldpdaalSSLSGGWLRKAALGRALVSNP 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 147 KLLLMDEPLSALDptmrIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIV 207
Cdd:PRK11147  176 DVLLLDEPTNHLD----IETIEWLEGFLKTFQGSIIFISHDRSFIRNMATRIVDLDRGKLV 232
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
20-231 3.96e-12

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 64.90  E-value: 3.96e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEK-AQGIIKVdneIWQDEKEFLpvQKRKIGFVFQ----DYAlFPnmTV 94
Cdd:PRK15056   25 DASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRlASGKISI---LGQPTRQAL--QKNLVAYVPQseevDWS-FP--VL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LENLFFVN-------------KDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDpt 161
Cdd:PRK15056   97 VEDVVMMGryghmgwlrrakkRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVD-- 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 162 mrIKLQDEILQLHKEF--ETTTILVS-HDPSEIYKLSNRVIVLKdGKIVDDGTAKSVLlkTSGSAKFSFEGKL 231
Cdd:PRK15056  175 --VKTEARIISLLRELrdEGKTMLVStHNLGSVTEFCDYTVMVK-GTVLASGPTETTF--TAENLELAFSGVL 242
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 20-209 1.16e-11

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 64.46  E-value: 1.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQgiikVDNEIWQDEKEF---LPVQ--KRKIGFVFQD---YALFPN 91
Cdd:TIGR02633 278 DVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGK----FEGNVFINGKPVdirNPAQaiRAGIAMVPEDrkrHGIVPI 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 MTVLENLFF-----------VNKDKELANHLLEITELwELKNRLPN----SLSGGQKQRVSLCRALMNRPKLLLMDEPLS 156
Cdd:TIGR02633 354 LGVGKNITLsvlksfcfkmrIDAAAELQIIGSAIQRL-KVKTASPFlpigRLSGGNQQKAVLAKMLLTNPRVLILDEPTR 432

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1441214933 157 ALDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDD 209
Cdd:TIGR02633 433 GVDVGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGKLKGD 484
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 15-209 1.31e-11

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 64.25  E-value: 1.31e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  15 GVMNLD-VNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIkvdneIWQDEkeflPV--------QKRKIGFVFQ 84
Cdd:PRK10762   16 GVKALSgAALNVYPGRVMALVGENGAGKSTMMKVLTGIyTRDAGSI-----LYLGK----EVtfngpkssQEAGIGIIHQ 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  85 DYALFPNMTVLENLF----FVN--------KDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMD 152
Cdd:PRK10762   87 ELNLIPQLTIAENIFlgreFVNrfgridwkKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMD 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 153 EPLSALDPTMRIKLQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDD 209
Cdd:PRK10762  167 EPTDALTDTETESLFRVIREL-KSQGRGIVYISHRLKEIFEICDDVTVFRDGQFIAE 222
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 20-215 1.50e-11

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 63.18  E-value: 1.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKT-TLLRSL----AGLEKAQGIIKVDNEiwqdekEFLP--VQKRKIGFVFQD--YALFP 90
Cdd:PRK10418   21 GVSLTLQRGRVLALVGGSGSGKSlTCAAALgilpAGVRQTAGRVLLDGK------PVAPcaLRGRKIATIMQNprSAFNP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 --NMT--VLENLFFVNKDKELANhLLEITELWELKNRL------PNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDP 160
Cdd:PRK10418   95 lhTMHthARETCLALGKPADDAT-LTAALEAVGLENAArvlklyPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDV 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 161 TMRIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSV 215
Cdd:PRK10418  174 VAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETL 228
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 21-209 1.72e-11

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 64.05  E-value: 1.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEiwqdekeflPVQKRKIG-----F--VFQDYALFPNM 92
Cdd:COG4615   351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLyRPESGEILLDGQ---------PVTADNREayrqlFsaVFSDFHLFDRL 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  93 TVLENLFfvnkDKELANHLL---EITELWELKN-RLPN-SLSGGQKQRVSLCRALM-NRPKLLLmDEPLSALDPTMRIKL 166
Cdd:COG4615   422 LGLDGEA----DPARARELLerlELDHKVSVEDgRFSTtDLSQGQRKRLALLVALLeDRPILVF-DEWAADQDPEFRRVF 496

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1441214933 167 QDEILQLHKEFETTTILVSHDpsEIY-KLSNRVIVLKDGKIVDD 209
Cdd:COG4615   497 YTELLPELKARGKTVIAISHD--DRYfDLADRVLKMDYGKLVEL 538
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 20-206 1.97e-11

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 63.79  E-value: 1.97e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAqgiiKVDNEIWQDEKEFL---PVQ--KRKIGFVFQD---YALFPN 91
Cdd:PRK13549  280 DVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPG----RWEGEIFIDGKPVKirnPQQaiAQGIAMVPEDrkrDGIVPV 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 MTVLENLFFVNKDK----ELANHLLEIT----ELWELKNRLPN------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:PRK13549  356 MGVGKNITLAALDRftggSRIDDAAELKtileSIQRLKVKTASpelaiaRLSGGNQQKAVLAKCLLLNPKILILDEPTRG 435

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1441214933 158 LDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:PRK13549  436 IDVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGLSDRVLVMHEGKL 483
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 15-208 3.86e-11

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 62.82  E-value: 3.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  15 GVMNLD-VNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQG-IIKVDNEI-WQDEKEFLpvqKRKIGFVFQDYALFP 90
Cdd:PRK10982   10 GVKALDnVNLKVRPHSIHALMGENGAGKSTLLKCLFGIyQKDSGsILFQGKEIdFKSSKEAL---ENGISMVHQELNLVL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  91 NMTVLENL---------FFVNKDKELANHLLEITEL---WELKNRLPNsLSGGQKQRVSLCRALMNRPKLLLMDEPLSAL 158
Cdd:PRK10982   87 QRSVMDNMwlgryptkgMFVDQDKMYRDTKAIFDELdidIDPRAKVAT-LSVSQMQMIEIAKAFSYNAKIVIMDEPTSSL 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1441214933 159 DPTMRIKLQDEILQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVD 208
Cdd:PRK10982  166 TEKEVNHLFTIIRKL-KERGCGIVYISHKMEEIFQLCDEITILRDGQWIA 214
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 20-221 4.91e-11

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 63.04  E-value: 4.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNeiWQDEKEFLPVQKRKIGFVFQDYALFPNmTVLENL 98
Cdd:TIGR00957 1304 HINVTIHGGEKVGIVGRTGAGKSSLTLGLFRiNESAEGEIIIDG--LNIAKIGLHDLRFKITIIPQDPVLFSG-SLRMNL 1380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   99 --FFVNKDKELANHLlEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMrik 165
Cdd:TIGR00957 1381 dpFSQYSDEEVWWAL-ELAHLKTFVSALPDkldhecaeggeNLSVGQRQLVCLARALLRKTKILVLDEATAAVDLET--- 1456

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933  166 lqDEILQ--LHKEFETTTIL-VSHDPSEIYKLSnRVIVLKDGKIVDDGtAKSVLLKTSG 221
Cdd:TIGR00957 1457 --DNLIQstIRTQFEDCTVLtIAHRLNTIMDYT-RVIVLDKGEVAEFG-APSNLLQQRG 1511
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 25-204 4.94e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 63.11  E-value: 4.94e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   25 IRSKDFVALTGLSGSGKTTLLRSLAG---------LEKAQGIIKVDNEIWQDekeflpvqkrkIGFVFQDYALFPNMTVL 95
Cdd:TIGR01257 1962 VRPGECFGLLGVNGAGKTTTFKMLTGdttvtsgdaTVAGKSILTNISDVHQN-----------MGYCPQFDAIDDLLTGR 2030

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   96 ENLFFVNKDKELANHLLEITELWELK--------NRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQ 167
Cdd:TIGR01257 2031 EHLYLYARLRGVPAEEIEKVANWSIQslglslyaDRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLW 2110

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1441214933  168 DEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDG 204
Cdd:TIGR01257 2111 NTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKG 2146
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
20-219 6.86e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 62.45  E-value: 6.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNEIWQDEKEFLPVQKRkIGFVFQDYA--LFPNMTVLE 96
Cdd:NF033858   19 DVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQqGRVEVLGGDMADARHRRAVCPR-IAYMPQGLGknLYPTLSVFE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NL-FFVNkdkeLANH-----------LLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:NF033858   98 NLdFFGR----LFGQdaaerrrrideLLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRR 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 165 KLQDEILQLHKEFETTTILVS---HDPSEIYklsNRVIVLKDGKIVDDGTAKSVLLKT 219
Cdd:NF033858  174 QFWELIDRIRAERPGMSVLVAtayMEEAERF---DWLVAMDAGRVLATGTPAELLART 228
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 20-204 6.89e-11

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 61.41  E-value: 6.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKvdneiwqdekeflpvQKRKIGFVFQDYALFPNmTVLENL 98
Cdd:cd03291    55 NINLKIEKGEMLAITGSTGSGKTSLLMLILGeLEPSEGKIK---------------HSGRISFSSQFSWIMPG-TIKENI 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FF-VNKDKELANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDptmrIKL 166
Cdd:cd03291   119 IFgVSYDEYRYKSVVKACQLEEDITKFPEkdntvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFGYLD----VFT 194

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1441214933 167 QDEILQ--LHKEFETTTILVSHDPSEIYKLSNRVIVLKDG 204
Cdd:cd03291   195 EKEIFEscVCKLMANKTRILVTSKMEHLKKADKILILHEG 234
PLN03140 PLN03140
ABC transporter G family member; Provisional
 32-159 1.04e-10

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 62.17  E-value: 1.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   32 ALTGLSGSGKTTLLRSLAGlEKAQGIIKVDNEIwqdeKEFLPVQK---RKIGFVFQDYALFPNMTVLENLFF-------- 100
Cdd:PLN03140   910 ALMGVSGAGKTTLMDVLAG-RKTGGYIEGDIRI----SGFPKKQEtfaRISGYCEQNDIHSPQVTVRESLIYsaflrlpk 984

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933  101 -VNKDKEL--ANHLLEITELWELKNR---LP--NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALD 159
Cdd:PLN03140   985 eVSKEEKMmfVDEVMELVELDNLKDAivgLPgvTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLD 1051
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 8-206 3.24e-10

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 59.48  E-value: 3.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   8 KELHGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQDekefLPVQK-RK-IGFVFQD 85
Cdd:cd03289    11 KYTEGGNAVLE-NISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGDIQIDGVSWNS----VPLQKwRKaFGVIPQK 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  86 YALFPNmTVLENL--FFVNKDKELanhlLEITELWELK---NRLPNSL-----------SGGQKQRVSLCRALMNRPKLL 149
Cdd:cd03289    86 VFIFSG-TFRKNLdpYGKWSDEEI----WKVAEEVGLKsviEQFPGQLdfvlvdggcvlSHGHKQLMCLARSVLSKAKIL 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 150 LMDEPLSALDPtmrIKLQDEILQLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:cd03289   161 LLDEPSAHLDP---ITYQVIRKTLKQAFADCTVILSEHRIEAMLECQRFLVIEENKV 214
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
21-209 4.49e-10

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 59.92  E-value: 4.49e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEiwqdekeflPVQKRKI------GFVF------QDyA 87
Cdd:PRK11288  272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRtAGQVYLDGK---------PIDIRSPrdairaGIMLcpedrkAE-G 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  88 LFPNMTVLENL------------FFVNKDKELANHLLEITELwelKNRLPN------SLSGGQKQRVSLCRALMNRPKLL 149
Cdd:PRK11288  342 IIPVHSVADNInisarrhhlragCLINNRWEAENADRFIRSL---NIKTPSreqlimNLSGGNQQKAILGRWLSEDMKVI 418

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 150 LMDEPLSALDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKIVDD 209
Cdd:PRK11288  419 LLDEPTRGIDVGAKHEIYNVIYELAAQ-GVAVLFVSSDLPEVLGVADRIVVMREGRIAGE 477
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 126-203 5.29e-10

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 60.04  E-value: 5.29e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933  126 NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEFETTTILVSHDPSEIyKLSNRVIVLKD 203
Cdd:PTZ00265   578 SKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAHRLSTI-RYANTIFVLSN 654
PLN03130 PLN03130
ABC transporter C family member; Provisional
 10-226 5.98e-10

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 59.75  E-value: 5.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   10 LHGsngvmnldVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNeiwQDEKEFLPVQKRKI-GFVFQDYA 87
Cdd:PLN03130  1255 LHG--------LSFEISPSEKVGIVGRTGAGKSSMLNALFRIvELERGRILIDG---CDISKFGLMDLRKVlGIIPQAPV 1323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   88 LFPNmTVLENL--FFVNKDKELANHLlEITELWELKNRLPNSL-----------SGGQKQRVSLCRALMNRPKLLLMDEP 154
Cdd:PLN03130  1324 LFSG-TVRFNLdpFNEHNDADLWESL-ERAHLKDVIRRNSLGLdaevseagenfSVGQRQLLSLARALLRRSKILVLDEA 1401

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1441214933  155 LSALDPTMRIKLQDEIlqlHKEFETTTILV-SHDPSEIYKlSNRVIVLKDGKIVDDGTAKSvLLKTSGSAkFS 226
Cdd:PLN03130  1402 TAAVDVRTDALIQKTI---REEFKSCTMLIiAHRLNTIID-CDRILVLDAGRVVEFDTPEN-LLSNEGSA-FS 1468
PLN03232 PLN03232
ABC transporter C family member; Provisional
 31-225 1.33e-09

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 58.83  E-value: 1.33e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   31 VALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNeiwQDEKEF-LPVQKRKIGFVFQDYALFPNmTVLENL--FFVNKDKE 106
Cdd:PLN03232  1265 VGVVGRTGAGKSSMLNALFRIvELEKGRIMIDD---CDVAKFgLTDLRRVLSIIPQSPVLFSG-TVRFNIdpFSEHNDAD 1340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  107 LANhLLEITELWELKNRLP-----------NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDptMRIklqDEILQ--L 173
Cdd:PLN03232  1341 LWE-ALERAHIKDVIDRNPfgldaevseggENFSVGQRQLLSLARALLRRSKILVLDEATASVD--VRT---DSLIQrtI 1414

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1441214933  174 HKEFETTTILV-SHDPSEIYKlSNRVIVLKDGKIVDDGTAKSvLLKTSGSAKF 225
Cdd:PLN03232  1415 REEFKSCTMLViAHRLNTIID-CDKILVLSSGQVLEYDSPQE-LLSRDTSAFF 1465
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 31-206 1.48e-09

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 58.26  E-value: 1.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  31 VALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEIwqdekeflpvqkrKIGFVFQdyalfpnmtvlENLFFVNKDKELAN 109
Cdd:PRK10636  341 IGLLGRNGAGKSTLIKLLAGeLAPVSGEIGLAKGI-------------KLGYFAQ-----------HQLEFLRADESPLQ 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 110 HLLEITELwELKNRLPNSL-----------------SGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILq 172
Cdd:PRK10636  397 HLARLAPQ-ELEQKLRDYLggfgfqgdkvteetrrfSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALI- 474

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1441214933 173 lhkEFETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:PRK10636  475 ---DFEGALVVVSHDRHLLRSTTDDLYLVHDGKV 505
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
20-221 1.73e-09

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 58.19  E-value: 1.73e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLA-GLEKAQGIIKVDNEIWQDEKefLPVQKRKIGFVFQDYALFPNmTVLENL 98
Cdd:PRK10789  333 NVNFTLKPGQMLGICGPTGSGKSTLLSLIQrHFDVSEGDIRFHDIPLTKLQ--LDSWRSRLAVVSQTPFLFSD-TVANNI 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFVNKDKELAnhllEITELWELKN------RLPNS-----------LSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPt 161
Cdd:PRK10789  410 ALGRPDATQQ----EIEHVARLASvhddilRLPQGydtevgergvmLSGGQKQRISIARALLLNAEILILDDALSAVDG- 484

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1441214933 162 mriKLQDEILQLHKEF--ETTTILVSHDPSEIYKLSNrVIVLKDGKIVDDGTAKSvLLKTSG 221
Cdd:PRK10789  485 ---RTEHQILHNLRQWgeGRTVIISAHRLSALTEASE-ILVMQHGHIAQRGNHDQ-LAQQSG 541
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 20-189 2.23e-09

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 57.84  E-value: 2.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQG---IIKVDNEIWqdekeFLPvQKRKIGF-VFQDYALFPnMTVL 95
Cdd:TIGR00954 470 SLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGgrlTKPAKGKLF-----YVP-QRPYMTLgTLRDQIIYP-DSSE 542

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  96 EnlfFVNK---DKELA--------NHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMri 164
Cdd:TIGR00954 543 D---MKRRglsDKDLEqildnvqlTHILEREGGWSAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDV-- 617

                         170       180
                  ....*....|....*....|....*
gi 1441214933 165 klQDEILQLHKEFETTTILVSHDPS 189
Cdd:TIGR00954 618 --EGYMYRLCREFGITLFSVSHRKS 640
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 32-159 3.13e-09

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 57.81  E-value: 3.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   32 ALTGLSGSGKTTLLRSLAGlEKAQGIIKVDNEIwqdeKEFLPVQK---RKIGFVFQDYALFPNMTVLENLFF-------- 100
Cdd:TIGR00956  793 ALMGASGAGKTTLLNVLAE-RVTTGVITGGDRL----VNGRPLDSsfqRSIGYVQQQDLHLPTSTVRESLRFsaylrqpk 867

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933  101 -VNKdKELANHLLEITELWELKNR------LPNS-LSGGQKQRVSLCRALMNRPKLLL-MDEPLSALD 159
Cdd:TIGR00956  868 sVSK-SEKMEYVEEVIKLLEMESYadavvgVPGEgLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLD 934
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 20-204 3.78e-09

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 57.23  E-value: 3.78e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKvdneiwqdekeflpvQKRKIGFVFQDYALFPNmTVLENL 98
Cdd:TIGR01271  444 NISFKLEKGQLLAVAGSTGSGKSSLLMMIMGeLEPSEGKIK---------------HSGRISFSPQTSWIMPG-TIKDNI 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   99 FF-VNKDKELANHLLEITELWELKNRLPN-----------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDptmrIKL 166
Cdd:TIGR01271  508 IFgLSYDEYRYTSVIKACQLEEDIALFPEkdktvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFTHLD----VVT 583

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1441214933  167 QDEILQ--LHKEFETTTILVSHDPSEIYKLSNRVIVLKDG 204
Cdd:TIGR01271  584 EKEIFEscLCKLMSNKTRILVTSKLEHLKKADKILLLHEG 623
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
25-200 3.85e-09

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 57.13  E-value: 3.85e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  25 IRSKDFVALTGLSGSGKTTLLRSLAGLEKAqgiikvdneiwqDEKEFLPVQK--RKIGFVFQDYalfpNMTVLENLFFVN 102
Cdd:PRK13409  362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKP------------DEGEVDPELKisYKPQYIKPDY----DGTVEDLLRSIT 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 103 KD-------KELANHLleitELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHK 175
Cdd:PRK13409  426 DDlgssyykSEIIKPL----QLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAE 501

                         170       180
                  ....*....|....*....|....*
gi 1441214933 176 EFETTTILVSHDPSEIYKLSNRVIV 200
Cdd:PRK13409  502 EREATALVVDHDIYMIDYISDRLMV 526
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 31-200 1.05e-08

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 55.56  E-value: 1.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  31 VALTGLSGSGKTTLLRSLAGLEKAqgiikvdneiwqDEKEFLPVQK--RKIGFVFQDYalfpNMTVLENLFFVNKDK--- 105
Cdd:COG1245   369 LGIVGPNGIGKTTFAKILAGVLKP------------DEGEVDEDLKisYKPQYISPDY----DGTVEEFLRSANTDDfgs 432

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 106 -----ELANHLleitELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEFETT 180
Cdd:COG1245   433 syyktEIIKPL----GLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKT 508

                         170       180
                  ....*....|....*....|
gi 1441214933 181 TILVSHDPSEIYKLSNRVIV 200
Cdd:COG1245   509 AMVVDHDIYLIDYISDRLMV 528
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
20-206 1.23e-08

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 55.56  E-value: 1.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKaqgiiKVDNEIWQDEKEFLPVQ-----KRKIGFVFQ---DYALFPN 91
Cdd:PRK09700  281 DISFSVCRGEILGFAGLVGSGRTELMNCLFGVDK-----RAGGEIRLNGKDISPRSpldavKKGMAYITEsrrDNGFFPN 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 MTVLENLFFVNKDKE--------LANHLLEIT------ELWELK----NRLPNSLSGGQKQRVSLCRALMNRPKLLLMDE 153
Cdd:PRK09700  356 FSIAQNMAISRSLKDggykgamgLFHEVDEQRtaenqrELLALKchsvNQNITELSGGNQQKVLISKWLCCCPEVIIFDE 435

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 154 PLSALDptmrIKLQDEILQLHKEFE---TTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:PRK09700  436 PTRGID----VGAKAEIYKVMRQLAddgKVILMVSSELPEIITVCDRIAVFCEGRL 487
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 15-201 2.30e-08

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 52.57  E-value: 2.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  15 GVMNLDVNL-DIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGiikvDNEIWqdekeflpvqkrkigfvfqdyalfPNMT 93
Cdd:cd03222    11 GVFFLLVELgVVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNG----DNDEW------------------------DGIT 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENLFFVnkdkelanhlleitelwelknrlpnSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQL 173
Cdd:cd03222    63 PVYKPQYI-------------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRL 117

                         170       180
                  ....*....|....*....|....*...
gi 1441214933 174 HKEFETTTILVSHDPSEIYKLSNRVIVL 201
Cdd:cd03222   118 SEEGKKTALVVEHDLAVLDYLSDRIHVF 145
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 35-186 9.20e-08

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 52.71  E-value: 9.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  35 GLSGSGKTTLLrSLAGLEKAQGIikvDNE-------------IWQdekeflpvQKRKIGFV----FQDYALFPNM-TVLE 96
Cdd:PRK10938  293 GPNGAGKSTLL-SLITGDHPQGY---SNDltlfgrrrgsgetIWD--------IKKHIGYVssslHLDYRVSTSVrNVIL 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  97 NLFF---------VNKDKELANHLLEITELWELKNRLP-NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKL 166
Cdd:PRK10938  361 SGFFdsigiyqavSDRQQKLAQQWLDILGIDKRTADAPfHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLV 440

                         170       180
                  ....*....|....*....|
gi 1441214933 167 QDEILQLHKEFETTTILVSH 186
Cdd:PRK10938  441 RRFVDVLISEGETQLLFVSH 460
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 8-185 9.72e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 52.99  E-value: 9.72e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933    8 KELHGSNGVMNlDVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQDEKefLPVQKRKIGFVFQDYA 87
Cdd:TIGR01271 1226 KYTEAGRAVLQ-DLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTEGEIQIDGVSWNSVT--LQTWRKAFGVIPQKVF 1302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   88 LFPNmTVLENL--FFVNKDKELanhlLEITELWELKN---RLPNSL-----------SGGQKQRVSLCRALMNRPKLLLM 151
Cdd:TIGR01271 1303 IFSG-TFRKNLdpYEQWSDEEI----WKVAEEVGLKSvieQFPDKLdfvlvdggyvlSNGHKQLMCLARSILSKAKILLL 1377

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1441214933  152 DEPLSALDPtmrIKLQDEILQLHKEFETTTILVS 185
Cdd:TIGR01271 1378 DEPSAHLDP---VTLQIIRKTLKQSFSNCTVILS 1408
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 20-206 1.16e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 52.42  E-value: 1.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGL-EKAQGIIKVDNEIWQDEKEFLPVQKrkiGFVF-----QDYALFPNMT 93
Cdd:PRK10982  266 DVSFDLHKGEILGIAGLVGAKRTDIVETLFGIrEKSAGTITLHGKKINNHNANEAINH---GFALvteerRSTGIYAYLD 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  94 VLENLFFVNKDKE------LANHLLEITELW---ELKNRLPN------SLSGGQKQRVSLCRALMNRPKLLLMDEPLSAL 158
Cdd:PRK10982  343 IGFNSLISNIRNYknkvglLDNSRMKSDTQWvidSMRVKTPGhrtqigSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGI 422

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1441214933 159 DPTMRIKLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:PRK10982  423 DVGAKFEIYQLIAELAKK-DKGIIIISSEMPELLGITDRILVMSNGLV 469
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 31-187 1.60e-07

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 52.24  E-value: 1.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  31 VALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIwqdekeflpvqkrKIGFVFQDY-ALFPNMTVLEnlffvnkdkELA 108
Cdd:TIGR03719 351 VGVIGPNGAGKSTLFRMITGQEQPdSGTIEIGETV-------------KLAYVDQSRdALDPNKTVWE---------EIS 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 109 NHLLEItelwELKNRLPNS--------------------LSGGQKQRVSLCRALMNRPKLLLMDEPLSALD-PTMRiKLQ 167
Cdd:TIGR03719 409 GGLDII----KLGKREIPSrayvgrfnfkgsdqqkkvgqLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDvETLR-ALE 483

                         170       180
                  ....*....|....*....|
gi 1441214933 168 DEILqlhkEFETTTILVSHD 187
Cdd:TIGR03719 484 EALL----NFAGCAVVISHD 499
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 18-199 1.71e-07

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 50.01  E-value: 1.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  18 NLDVNLDIRSkdFVALTGLSGSGKTTLLrsLAGLEKAQGIIKVDneiwqdekeFLPvqkrkigfvfqdyALFPNMTVlen 97
Cdd:cd03238    13 NLDVSIPLNV--LVVVTGVSGSGKSTLV--NEGLYASGKARLIS---------FLP-------------KFSRNKLI--- 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  98 lfFVNKDKELANHLLEITELwelkNRLPNSLSGGQKQRVSLCRALMNRPK--LLLMDEPLSALDPTMRIKLQDEILQLHK 175
Cdd:cd03238    64 --FIDQLQFLIDVGLGYLTL----GQKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDINQLLEVIKGLID 137

                         170       180
                  ....*....|....*....|....
gi 1441214933 176 EfETTTILVSHDPSEIyKLSNRVI 199
Cdd:cd03238   138 L-GNTVILIEHNLDVL-SSADWII 159
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 21-221 1.75e-07

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 51.06  E-value: 1.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  21 VNLDIRSKDFVALTGLSGSGKTTLlrSLAGLEKA---QGIIKVDN-EIWQdekefLPVQ--KRKIGFVFQDYALFPNMTV 94
Cdd:cd03288    40 VKAYIKPGQKVGICGRTGSGKSSL--SLAFFRMVdifDGKIVIDGiDISK-----LPLHtlRSRLSIILQDPILFSGSIR 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  95 LenlffvNKDKELA---NHLLEITELWELKN---RLPNSL-----------SGGQKQRVSLCRALMNRPKLLLMDEPLSA 157
Cdd:cd03288   113 F------NLDPECKctdDRLWEALEIAQLKNmvkSLPGGLdavvteggenfSVGQRQLFCLARAFVRKSSILIMDEATAS 186

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1441214933 158 LDPTMRIKLQDEILQLHKefETTTILVSHDPSEIYKlSNRVIVLKDGKIVDDGTAKSVLLKTSG 221
Cdd:cd03288   187 IDMATENILQKVVMTAFA--DRTVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLLAQEDG 247
PLN03073 PLN03073
ABC transporter F family; Provisional
 18-206 2.61e-07

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 51.40  E-value: 2.61e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  18 NLDVNLDIRSKdfVALTGLSGSGKTTLLRSLAG-LEKAQGII----KVDNEIW-QDEKEFLPVQKRKIGFVFQDYALFPn 91
Cdd:PLN03073  527 NLNFGIDLDSR--IAMVGPNGIGKSTILKLISGeLQPSSGTVfrsaKVRMAVFsQHHVDGLDLSSNPLLYMMRCFPGVP- 603

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  92 mtvlenlffvnkDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDptmrIKLQDEIL 171
Cdd:PLN03073  604 ------------EQKLRAHLGSFGVTGNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD----LDAVEALI 667

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1441214933 172 QLHKEFETTTILVSHDPSEIYKLSNRVIVLKDGKI 206
Cdd:PLN03073  668 QGLVLFQGGVLMVSHDEHLISGSVDELWVVSEGKV 702
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 26-201 3.58e-07

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 50.06  E-value: 3.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  26 RSKDFVALTGLSGSGKTTLLRSLAGLEKAQGIIKVDNEIWQD------------------EKEFLPVQKRkigfvfQDYA 87
Cdd:cd03236    24 REGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPDWDEildefrgselqnyftkllEGDVKVIVKP------QYVD 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  88 LFPNM---TVLENLFFVNkDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRI 164
Cdd:cd03236    98 LIPKAvkgKVGELLKKKD-ERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRL 176

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1441214933 165 KLQDEILQLHKEfETTTILVSHDPSEIYKLSNRVIVL 201
Cdd:cd03236   177 NAARLIRELAED-DNYVLVVEHDLAVLDYLSDYIHCL 212
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
76-163 3.96e-07

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 50.89  E-value: 3.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  76 KRKIGFVFQDYALFPNMTVLENL------FFVNKDK--ELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPK 147
Cdd:NF033858  338 RRRVGYMSQAFSLYGELTVRQNLelharlFHLPAAEiaARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPE 417

                          90
                  ....*....|....*.
gi 1441214933 148 LLLMDEPLSALDPTMR 163
Cdd:NF033858  418 LLILDEPTSGVDPVAR 433
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 29-187 4.11e-07

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 50.72  E-value: 4.11e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  29 DFVALTGLSGSGKTTLLRSLAGLEKAQ-GIIKVDNeiwqdekeflpvqKRKIGFvFQDY--ALFPNMTVLENL------F 99
Cdd:PRK11147  346 DKIALIGPNGCGKTTLLKLMLGQLQADsGRIHCGT-------------KLEVAY-FDQHraELDPEKTVMDNLaegkqeV 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 100 FVN-KDKELANHLLEIteLWELKN-RLP-NSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDpTMRIKLQDEILQlhkE 176
Cdd:PRK11147  412 MVNgRPRHVLGYLQDF--LFHPKRaMTPvKALSGGERNRLLLARLFLKPSNLLILDEPTNDLD-VETLELLEELLD---S 485

                         170
                  ....*....|.
gi 1441214933 177 FETTTILVSHD 187
Cdd:PRK11147  486 YQGTVLLVSHD 496
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 27-191 8.45e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 47.75  E-value: 8.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   27 SKDFVALTGLSGSGKTTLLRSLAGLEKAQGiikvdneiwqdekeflpvqkrkigfvfqdyalfpnmtvlENLFFVNKDKE 106
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPG---------------------------------------GGVIYIDGEDI 41

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  107 LANHLLEITElwELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI-----LQLHKEFETTT 181
Cdd:smart00382  42 LEEVLDQLLL--IIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEelrllLLLKSEKNLTV 119

                          170
                   ....*....|
gi 1441214933  182 ILVSHDPSEI 191
Cdd:smart00382 120 ILTTNDEKDL 129
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
20-218 9.13e-07

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 49.04  E-value: 9.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAG-LEKAQGIIKVDNEIwqdekeflpvqkrkiGFVFQDYALFPNMTVLENL 98
Cdd:PRK13546   42 DISLKAYEGDVIGLVGINGSGKSTLSNIIGGsLSPTVGKVDRNGEV---------------SVIAISAGLSGQLTGIENI 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  99 FFV--------NKDKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEI 170
Cdd:PRK13546  107 EFKmlcmgfkrKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKI 186

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1441214933 171 LQLhKEFETTTILVSHDPSEIYKLSNRVIVLKDGKIVDDGTAKSVLLK 218
Cdd:PRK13546  187 YEF-KEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPK 233
PLN03073 PLN03073
ABC transporter F family; Provisional
 33-186 3.54e-06

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 47.93  E-value: 3.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  33 LTGLSGSGKTTLLRSLA-----GLEKAQGIIKVDNEIWQD--------------------EKEFLPVQKRKIGF--VFQD 85
Cdd:PLN03073  208 LVGRNGTGKTTFLRYMAmhaidGIPKNCQILHVEQEVVGDdttalqcvlntdiertqlleEEAQLVAQQRELEFetETGK 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  86 YALFPNMTVLENLffVNKDKELANHLLEITELW-----------------ELKNRLPNSLSGGQKQRVSLCRALMNRPKL 148
Cdd:PLN03073  288 GKGANKDGVDKDA--VSQRLEEIYKRLELIDAYtaearaasilaglsftpEMQVKATKTFSGGWRMRIALARALFIEPDL 365

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1441214933 149 LLMDEPLSALDPTMRIKLQDEILQLHKEFetttILVSH 186
Cdd:PLN03073  366 LLLDEPTNHLDLHAVLWLETYLLKWPKTF----IVVSH 399
PLN03140 PLN03140
ABC transporter G family member; Provisional
 33-216 4.52e-06

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 47.92  E-value: 4.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933   33 LTGLSGSGKTTLLRSLAGleKAQGIIKVDNEIWQDE---KEFLPvqKRKIGFVFQDYALFPNMTVLENLFF------VNK 103
Cdd:PLN03140   196 LLGPPSSGKTTLLLALAG--KLDPSLKVSGEITYNGyrlNEFVP--RKTSAYISQNDVHVGVMTVKETLDFsarcqgVGT 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  104 DKELANHL-----------------------------------------LEITELWELKNRLPNSLSGGQKQRVSLCRAL 142
Cdd:PLN03140   272 RYDLLSELarrekdagifpeaevdlfmkatamegvksslitdytlkilgLDICKDTIVGDEMIRGISGGQKKRVTTGEMI 351

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1441214933  143 MNRPKLLLMDEPLSALDP--TMRI-KLQDEILQLHKefetTTILVS--HDPSEIYKLSNRVIVLKDGKIVDDGTAKSVL 216
Cdd:PLN03140   352 VGPTKTLFMDEISTGLDSstTYQIvKCLQQIVHLTE----ATVLMSllQPAPETFDLFDDIILLSEGQIVYQGPRDHIL 426
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 20-191 7.79e-06

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 45.63  E-value: 7.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  20 DVNLDIRSKDFVALTGLSGSGKTTLLRSLAGLEKAQgiikvDNEIWQDEKEFLPVQKRKIGFVFQDYALFPNMTVLENLF 99
Cdd:PRK13541   18 DLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPS-----SGNIYYKNCNINNIAKPYCTYIGHNLGLKLEMTVFENLK 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 100 FVNK---DKELANHLLEITELWELKNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRiKLQDEILQLHKE 176
Cdd:PRK13541   93 FWSEiynSAETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENR-DLLNNLIVMKAN 171

                         170
                  ....*....|....*
gi 1441214933 177 FETTTILVSHDPSEI 191
Cdd:PRK13541  172 SGGIVLLSSHLESSI 186
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 127-187 2.65e-05

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 45.16  E-value: 2.65e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1441214933 127 SLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEIlqlhKEFETTTILVSHD 187
Cdd:PRK10636  149 DFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDLDAVIWLEKWL----KSYQGTLILISHD 205
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 31-187 3.69e-05

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 44.72  E-value: 3.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  31 VALTGLSGSGKTTLLRSLAGLEKA-QGIIKVDNEIwqdekeflpvqkrKIGFVFQDY-ALFPNMTVLEnlffvnkdkela 108
Cdd:PRK11819  353 VGIIGPNGAGKSTLFKMITGQEQPdSGTIKIGETV-------------KLAYVDQSRdALDPNKTVWE------------ 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933 109 nhllEIT---ELWELKNRLPNS--------------------LSGGQKQRVSLCRALMNRPKLLLMDEPLSALD-PTMRi 164
Cdd:PRK11819  408 ----EISgglDIIKVGNREIPSrayvgrfnfkggdqqkkvgvLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDvETLR- 482

                         170       180
                  ....*....|....*....|...
gi 1441214933 165 KLQDEILqlhkEFETTTILVSHD 187
Cdd:PRK11819  483 ALEEALL----EFPGCAVVISHD 501
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 18-199 5.53e-05

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 43.40  E-value: 5.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  18 NL-DVNLDIRSKDFVALTGLSGSGKTTL-------------LRSLA--------GLEKAQgiikVDN------EIWQDEK 69
Cdd:cd03270    10 NLkNVDVDIPRNKLVVITGVSGSGKSSLafdtiyaegqrryVESLSayarqflgQMDKPD----VDSieglspAIAIDQK 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  70 EFLPVQKRKIGFVFQ--DY--ALFPNMTVLENLFFvnkdkelanhLLEITELWELKNRLPNSLSGGQKQRVSLCRAL-MN 144
Cdd:cd03270    86 TTSRNPRSTVGTVTEiyDYlrLLFARVGIRERLGF----------LVDVGLGYLTLSRSAPTLSGGEAQRIRLATQIgSG 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1441214933 145 RPKLL-LMDEPLSALDPTMRIKLQdEILQLHKEFETTTILVSHDPsEIYKLSNRVI 199
Cdd:cd03270   156 LTGVLyVLDEPSIGLHPRDNDRLI-ETLKRLRDLGNTVLVVEHDE-DTIRAADHVI 209
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 128-188 3.73e-04

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 40.04  E-value: 3.73e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1441214933 128 LSGGQKQRVSLCRAL----MNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEFeTTTILVSHDP 188
Cdd:cd03227    78 LSGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQALAEAILEHLVKG-AQVIVITHLP 141
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 2-45 6.50e-04

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 41.15  E-value: 6.50e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1441214933   2 IKIEIKKELHGSNGVM---------NL-DVNLDIRSKDFVALTGLSGSGKTTLL 45
Cdd:TIGR00630 598 KKIEVPAERRPGNGKFltlkgarenNLkNITVSIPLGLFTCITGVSGSGKSTLI 651
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 131-187 1.15e-03

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 40.26  E-value: 1.15e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1441214933 131 GQKQRVSLCRALMNRPKLLLMDEPLSALD-PTMRIkLQDEIlqlhKEFETTTILVSHD 187
Cdd:PRK15064  159 GWKLRVLLAQALFSNPDILLLDEPTNNLDiNTIRW-LEDVL----NERNSTMIIISHD 211
uvrA PRK00349
excinuclease ABC subunit UvrA;
3-45 1.93e-03

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 39.67  E-value: 1.93e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1441214933   3 KIEIKKELHGSNGVM---------NL-DVNLDIRSKDFVALTGLSGSGKTTLL 45
Cdd:PRK00349  600 KIEVPKERRKGNGKFlklkgarenNLkNVDVEIPLGKFTCVTGVSGSGKSTLI 652
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
 30-49 4.03e-03

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 37.84  E-value: 4.03e-03
                          10        20
                  ....*....|....*....|
gi 1441214933  30 FVALTGLSGSGKTTLLRSLA 49
Cdd:COG3267    45 FVVLTGEVGTGKTTLLRRLL 64
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
18-44 4.40e-03

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 38.47  E-value: 4.40e-03
                          10        20
                  ....*....|....*....|....*....
gi 1441214933  18 NL-DVNLDI-RSKdFVALTGLSGSGKTTL 44
Cdd:COG0178    15 NLkNIDVDIpRNK-LVVITGLSGSGKSSL 42
uvrA PRK00349
excinuclease ABC subunit UvrA;
3-44 5.56e-03

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 38.13  E-value: 5.56e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1441214933   3 KIEIK--KElHgsngvmNL-DVNLDI-RSKdFVALTGLSGSGKTTL 44
Cdd:PRK00349    5 KIIIRgaRE-H------NLkNIDLDIpRDK-LVVFTGLSGSGKSSL 42
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 111-187 6.06e-03

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 37.84  E-value: 6.06e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1441214933 111 LLEITELWelkNRLPNSLSGGQKQRVSLCRALMNRPKLLLMDEPLSALDPTMRIKLQDEILQLHKEfETTTILVSHD 187
Cdd:COG1245   199 KLGLENIL---DRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIYQRLNVARLIRELAEE-GKYVLVVEHD 271
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
31-49 6.49e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 36.43  E-value: 6.49e-03
                          10
                  ....*....|....*....
gi 1441214933  31 VALTGLSGSGKTTLLRSLA 49
Cdd:COG0645     2 ILVCGLPGSGKSTLARALA 20
CysC COG0529
Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; ...
 33-57 9.76e-03

Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; Adenylylsulfate kinase or related kinase is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 440295 [Multi-domain]  Cd Length: 189  Bit Score: 36.22  E-value: 9.76e-03
                          10        20
                  ....*....|....*....|....*
gi 1441214933  33 LTGLSGSGKTTLLRSLAGLEKAQGI 57
Cdd:COG0529    21 FTGLSGSGKSTLANALERRLFERGR 45
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 122-225 9.95e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 37.50  E-value: 9.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1441214933  122 NRLPNSLSGGQKQRVSLCRALMNRPK--LLLMDEPLSALDPTMRIKLQDEILQLHKEfETTTILVSHDPSEIyKLSNRVI 199
Cdd:PRK00635   471 ERALATLSGGEQERTALAKHLGAELIgiTYILDEPSIGLHPQDTHKLINVIKKLRDQ-GNTVLLVEHDEQMI-SLADRII 548

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1441214933  200 VLK------DGKIVDDGTAKSVLLKT-SGSAKF 225
Cdd:PRK00635   549 DIGpgagifGGEVLFNGSPREFLAKSdSLTAKY 581
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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