|
Name |
Accession |
Description |
Interval |
E-value |
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-371 |
0e+00 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 560.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAM 80
Cdd:COG3839 1 MASLELENVSKSY-GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDRNIAM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:COG3839 80 VFQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 161 PLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFI 240
Cdd:COG3839 160 PLSNLDAKLRVEMRAEIKRLHRRLG-----TTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGFI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 241 GSPSMNLIDAVIRkaGNDIVIEidfgkQVRIPLEKQMNLLAqiNKPVCFGIRPEHIMFAsvEDKENILHGVLTNIENMGN 320
Cdd:COG3839 235 GSPPMNLLPGTVE--GGGVRLG-----GVRLPLPAALAAAA--GGEVTLGIRPEHLRLA--DEGDGGLEATVEVVEPLGS 303
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 321 EKNLYFNIGARELIMRaVAQDVTLSdIGSIYSLKIDTSFCHLFDFYTEENL 371
Cdd:COG3839 304 ETLVHVRLGGQELVAR-VPGDTRLR-PGDTVRLAFDPERLHLFDAETGRRL 352
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-364 |
9.37e-172 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 482.81 E-value: 9.37e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAM 80
Cdd:PRK11650 1 MAGLKLQAVRKSYDGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPADRDIAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:PRK11650 81 VFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 161 PLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFI 240
Cdd:PRK11650 161 PLSNLDAKLRVQMRLEIQRLHRRLK-----TTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVASFI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 241 GSPSMNLIDAVIRKAGndivIEIDFGKQVRIPLEKQMNLLAqiNKPVCFGIRPEHImfaSVEDKENILHGVLTNIENMGN 320
Cdd:PRK11650 236 GSPAMNLLDGRVSADG----AAFELAGGIALPLGGGYRQYA--GRKLTLGIRPEHI---ALSSAEGGVPLTVDTVELLGA 306
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1468311694 321 EKNLYFNIGARELIMRaVAQDVTLsDIGSIYSLKIDTSFCHLFD 364
Cdd:PRK11650 307 DNLAHGRWGGQPLVVR-LPHQERP-AAGSTLWLHLPANQLHLFD 348
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
1-363 |
2.33e-156 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 444.09 E-value: 2.33e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYSNgfkaVH---GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG 77
Cdd:PRK11000 1 MASVTLRNVTKAYGD----VViskDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 IAMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFL 157
Cdd:PRK11000 77 VGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 158 FDEPLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVA 237
Cdd:PRK11000 157 LDEPLSNLDAALRVQMRIEISRLHKRLG-----RTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVA 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 238 SFIGSPSMNLIDAVIRKAGNDIV-IEIDFGKQVRIPLEKQMnllAQINKPVCFGIRPEHimFASVEDKENILHGVLTNIE 316
Cdd:PRK11000 232 GFIGSPKMNFLPVKVTATAIEQVqVELPNRQQVWLPVEGRG---VQVGANMSLGIRPEH--LLPSDIADVTLEGEVQVVE 306
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1468311694 317 NMGNEKNLYFNIGA--RELIMRavAQDVTLSDIGSIYSLKIDTSFCHLF 363
Cdd:PRK11000 307 QLGNETQIHIQIPAirQNLVYR--QNDVVLVEEGATFAIGLPPERCHLF 353
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-363 |
2.61e-150 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 427.98 E-value: 2.61e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAM 80
Cdd:COG3842 3 MPALELENVSKRY-GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:COG3842 82 VFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 161 PLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFI 240
Cdd:COG3842 162 PLSALDAKLREEMREELRRLQRELG-----ITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 241 GspSMNLIDAVIRKAGNDIViEIDfGKQVRIPLEKQmnllAQINKPVCFGIRPEHIMFASvEDKENILHGVLTNIENMGN 320
Cdd:COG3842 237 G--EANLLPGTVLGDEGGGV-RTG-GRTLEVPADAG----LAAGGPVTVAIRPEDIRLSP-EGPENGLPGTVEDVVFLGS 307
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1468311694 321 EKNLYFNIGA-RELIMRAVAQDVTLSDIGSIYSLKIDTSFCHLF 363
Cdd:COG3842 308 HVRYRVRLGDgQELVVRVPNRAALPLEPGDRVGLSWDPEDVVVL 351
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
4-222 |
7.74e-129 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 368.12 E-value: 7.74e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNgFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQ 83
Cdd:cd03301 1 VELENVTKRFGN-VTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRDIAMVFQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLS 163
Cdd:cd03301 80 NYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLS 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 164 NLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVD 222
Cdd:cd03301 160 NLDAKLRVQMRAELKRLQQRLG-----TTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
4-332 |
8.80e-111 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 327.49 E-value: 8.80e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNgFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLPAKERGIAMVF 82
Cdd:COG1118 3 IEVRNISKRFGS-FTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLnGRDLFTNLPPRERRVGFVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:COG1118 82 QHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 163 SNLDAKLRVTMRvkiAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIGS 242
Cdd:COG1118 162 GALDAKVRKELR---RWLRRLHDELG--GTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLGC 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 243 PsmNLIDAVIRKAgndiVIEIDfgkqvRIPLEKQMNLLAQinkPVCFGIRPEHIMFASVEDKENILHGVLTNIENMGNEK 322
Cdd:COG1118 237 V--NVLRGRVIGG----QLEAD-----GLTLPVAEPLPDG---PAVAGVRPHDIEVSREPEGENTFPATVARVSELGPEV 302
|
330
....*....|
gi 1468311694 323 NLYFNIGARE 332
Cdd:COG1118 303 RVELKLEDGE 312
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
4-241 |
8.82e-111 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 323.03 E-value: 8.82e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQ 83
Cdd:cd03300 1 IELENVSKFY-GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLS 163
Cdd:cd03300 80 NYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLG 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 164 NLDAKLRVTMRVKIAQLHRTLkeeGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIG 241
Cdd:cd03300 160 ALDLKLRKDMQLELKRLQKEL---GI--TFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
4-264 |
6.40e-108 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 321.13 E-value: 6.40e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQ 83
Cdd:PRK09452 15 VELRGISKSF-DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHVNTVFQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLS 163
Cdd:PRK09452 94 SYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLS 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 164 NLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIGsp 243
Cdd:PRK09452 174 ALDYKLRKQMQNELKALQRKLG-----ITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIG-- 246
|
250 260
....*....|....*....|...
gi 1468311694 244 SMNLIDAVI--RKAGNDIVIEID 264
Cdd:PRK09452 247 EINIFDATVieRLDEQRVRANVE 269
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
4-222 |
3.88e-106 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 310.61 E-value: 3.88e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQ 83
Cdd:cd03259 1 LELKGLSKTY-GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERRNIGMVFQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLS 163
Cdd:cd03259 80 DYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLS 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 164 NLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVD 222
Cdd:cd03259 160 ALDAKLREELREELKELQRELG-----ITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| ABC_arch_GlcV |
NF040933 |
glucose ABC transporter ATP-binding protein GlcV; |
2-299 |
1.25e-103 |
|
glucose ABC transporter ATP-binding protein GlcV;
Pssm-ID: 468866 [Multi-domain] Cd Length: 357 Bit Score: 309.62 E-value: 1.25e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 2 ANVSLRKVVKSYSNGFK---AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMV-----NNLPA 73
Cdd:NF040933 1 VTVRVENVTKIFKKGKKevvALDNVNLEIKSGEFFGILGPSGHGKTTFLRIIAGLEVPTDGEIYFDDKLVaspgkIIVPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 74 KERGIAMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKP 153
Cdd:NF040933 81 EDRNIGMVFQNWALYPNMTVFDNIAFPLKIKKVPKDEIEKKVKEVAEILGISEVLDRYPRELSGGQQQRVALARALVKNP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 154 EVFLFDEPLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKN 233
Cdd:NF040933 161 QVLLLDEPFSNLDARIRDSARALVKKIQRELK-----ITTIIVSHDPADIFSLADRAGVINNGKFQQVGKPEEIYDNPAN 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 234 KFVASFIGspSMNLIDAVIRkaGNDIVIeidfGKQVRIPLekqMNLLAQINKpVCFGIRPEHIMFA 299
Cdd:NF040933 236 IFVARLIG--DINLLEGKVE--EEGLVD----GNDLKIPL---PNPKLEAGE-VIIGIRPEDIDIS 289
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
4-242 |
6.01e-90 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 270.36 E-value: 6.01e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQ 83
Cdd:cd03296 3 IEVRNVSKRF-GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERNVGFVFQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYPHKTVFDNMAFGLKM----QRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFD 159
Cdd:cd03296 82 HYALFRHMTVFDNVAFGLRVkprsERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 160 EPLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASF 239
Cdd:cd03296 162 EPFGALDAKVRKELRRWLRRLHDELH-----VTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSF 236
|
...
gi 1468311694 240 IGS 242
Cdd:cd03296 237 LGE 239
|
|
| tungstate_WtpC |
NF040840 |
tungstate ABC transporter ATP-binding protein WtpC; |
16-329 |
9.09e-89 |
|
tungstate ABC transporter ATP-binding protein WtpC;
Pssm-ID: 468779 [Multi-domain] Cd Length: 347 Bit Score: 271.18 E-value: 9.09e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 16 GFKaVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQNYALYPHKTVFD 95
Cdd:NF040840 13 EFK-LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQNYMLFPHKTVFE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 96 NMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRV 175
Cdd:NF040840 92 NIAFGLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDELIR 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 176 KIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIGSPsmNLIDAVIRKA 255
Cdd:NF040840 172 EMKRWHREFG-----FTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFE--NIIEGVAEKG 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 256 GNDIVIEIDfGKQVRIPLEKQmnllaqinKPVCFGIRPEHIMFASVEDK---ENILHGVLTNIENMGNEKNLYFNIG 329
Cdd:NF040840 245 GEGTILDTG-NIKIELPEEKK--------GKVRIGIRPEDITISTEKVKtsaRNEFKGKVEEIEDLGPLVKLTLDVG 312
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
36-305 |
2.10e-88 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 269.75 E-value: 2.10e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 36 VGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRV 115
Cdd:TIGR01187 2 LGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEIKPRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 116 EDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIY 195
Cdd:TIGR01187 82 LEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLG-----ITFVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 196 VTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIGspSMNLIDAVIRKAGNDIVIeidFGKQVRIPLEK 275
Cdd:TIGR01187 157 VTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIG--EINVFEATVIERKSEQVV---LAGVEGRRCDI 231
|
250 260 270
....*....|....*....|....*....|
gi 1468311694 276 QMNLLAQINKPVCFGIRPEHIMFASVEDKE 305
Cdd:TIGR01187 232 YTDVPVEKDQPLHVVLRPEKIVIEEEDEAN 261
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
4-355 |
2.59e-88 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 270.44 E-value: 2.59e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGfKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQ 83
Cdd:PRK11432 7 VVLKNITKRFGSN-TVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRDICMVFQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAaekLEITDLL---ERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:PRK11432 86 SYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEA---LELVDLAgfeDRYVDQISGGQQQRVALARALILKPKVLLFDE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 161 PLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFI 240
Cdd:PRK11432 163 PLSNLDANLRRSMREKIRELQQQFN-----ITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFM 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 241 GSPsmNLIDAvirKAGNDIViEIdFGKQVRIPLEKQMNLlaqiNKPVC-FGIRPEHIMFAsvEDKENILHGVLTNIENMG 319
Cdd:PRK11432 238 GDA--NIFPA---TLSGDYV-DI-YGYRLPRPAAFAFNL----PDGECtVGVRPEAITLS--EQGEESQRCTIKHVAYMG 304
|
330 340 350
....*....|....*....|....*....|....*.
gi 1468311694 320 NEKNLYFNIGARELIMRAVAQDVTlSDIGSIYSLKI 355
Cdd:PRK11432 305 PQYEVTVDWHGQELLLQVNATQLQ-PDLGEHYYLEI 339
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
4-214 |
1.51e-82 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 250.85 E-value: 1.51e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG---FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPakeRGIAM 80
Cdd:cd03293 1 LEVRNVSKTYGGGggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPG---PDRGY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:cd03293 78 VFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDE 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 161 PLSNLDAKLRVTMRvkiAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLN 214
Cdd:cd03293 158 PFSALDALTREQLQ---EELLDIWRETG--KTVLLVTHDIDEAVFLADRVVVLS 206
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
4-224 |
2.47e-82 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 251.55 E-value: 2.47e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSY---SNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKergIAM 80
Cdd:COG1116 8 LELRGVSKRFptgGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGPD---RGV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:COG1116 85 VFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLLMDE 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 161 PLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHG-----KIMQVDTP 224
Cdd:COG1116 165 PFGALDALTRERLQDELLRLWQETG-----KTVLFVTHDVDEAVFLADRVVVLSARpgrivEEIDVDLP 228
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
5-241 |
2.76e-80 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 245.71 E-value: 2.76e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYSngfkaVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQN 84
Cdd:cd03299 5 NLSKDWKEFK-----LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRDISYVPQN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 85 YALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSN 164
Cdd:cd03299 80 YALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 165 LDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIG 241
Cdd:cd03299 160 LDVRTKEKLREELKKIRKEFG-----VTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLG 231
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
6-320 |
1.45e-77 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 243.59 E-value: 1.45e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQNY 85
Cdd:PRK11607 22 IRNLTKSF-DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPINMMFQSY 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 86 ALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNL 165
Cdd:PRK11607 101 ALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGAL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 166 DAKLRVTMRVKIAQLhrtLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIGspSM 245
Cdd:PRK11607 181 DKKLRDRMQLEVVDI---LERVG--VTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIG--SV 253
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 246 NLIDAVIRKAGNDIVIEIDFGkqVRIPLEKQMNLLAQINKPVCFGIRPEHIMFAS--VEDKENILHGVLTNIENMGN 320
Cdd:PRK11607 254 NVFEGVLKERQEDGLVIDSPG--LVHPLKVDADASVVDNVPVHVALRPEKIMLCEepPADGCNFAVGEVIHIAYLGD 328
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
4-243 |
6.46e-76 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 234.89 E-value: 6.46e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMV 81
Cdd:cd03295 1 IEFENVTKRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVElrRKIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAE--KLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFD 159
Cdd:cd03295 81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLAlvGLDPAEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 160 EPLSNLDAKLRVTMRVKIAQLHRTLKEegspaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASF 239
Cdd:cd03295 161 EPFGALDPITRDQLQEEFKRLQQELGK-----TIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEF 235
|
....
gi 1468311694 240 IGSP 243
Cdd:cd03295 236 VGAD 239
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
3-253 |
4.76e-74 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 233.82 E-value: 4.76e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 3 NVSLRKVVKSYSNGfKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVF 82
Cdd:PRK10851 2 SIEIANIKKSFGRT-QVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QNYALYPHKTVFDNMAFGLKM----QRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:PRK10851 81 QHYALFRHMTVFDNIAFGLTVlprrERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 159 DEPLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVAS 238
Cdd:PRK10851 161 DEPFGALDAQVRKELRRWLRQLHEELK-----FTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLE 235
|
250
....*....|....*
gi 1468311694 239 FIGspSMNLIDAVIR 253
Cdd:PRK10851 236 FMG--EVNRLQGTIR 248
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
19-240 |
8.67e-71 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 222.52 E-value: 8.67e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE------RGIAMVFQNYALYPHKT 92
Cdd:cd03294 39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKElrelrrKKISMVFQSFALLPHRT 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 93 VFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVT 172
Cdd:cd03294 119 VLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRRE 198
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 173 MRVKIAQLHRTLKEegspaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFI 240
Cdd:cd03294 199 MQDELLRLQAELQK-----TIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFF 261
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
6-217 |
8.38e-67 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 208.97 E-value: 8.38e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN----NLPAKERGIAMV 81
Cdd:cd03229 3 LKNVSKRY-GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTdledELPPLRRRIGMV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFGLkmqrcpkdeikrrvedaaekleitdllerkpkemSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:cd03229 82 FQDFALFPHLTVLENIALGL----------------------------------SGGQQQRVALARALAMDPDVLLLDEP 127
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 162 LSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:cd03229 128 TSALDPITRREVRALLKSLQAQLG-----ITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
4-218 |
2.07e-65 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 206.96 E-value: 2.07e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG---FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG--- 77
Cdd:cd03255 1 IELKNLSKTYGGGgekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 ---IAMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:cd03255 81 rrhIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 155 VFLFDEPLSNLDAKLRVTMRVKIAQLHrtlKEEGspATMIYVTHDQTEALtLGDRICVLNHGKI 218
Cdd:cd03255 161 IILADEPTGNLDSETGKEVMELLRELN---KEAG--TTIVVVTHDPELAE-YADRIIELRDGKI 218
|
|
| proV |
TIGR01186 |
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ... |
16-276 |
4.68e-64 |
|
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130254 [Multi-domain] Cd Length: 363 Bit Score: 208.17 E-value: 4.68e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 16 GFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE------RGIAMVFQNYALYP 89
Cdd:TIGR01186 5 GKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKQSPVElrevrrKKIGMVFQQFALFP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 90 HKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKL 169
Cdd:TIGR01186 85 HMTILQNTSLGPELLGWPEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSALDPLI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 170 RVTMRVKIAQLHRTLKEegspaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIG----SPSM 245
Cdd:TIGR01186 165 RDSMQDELKKLQATLQK-----TIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIGkvdlSQVF 239
|
250 260 270
....*....|....*....|....*....|.
gi 1468311694 246 NLIDAVIRKAGNDIVIEIDFGKQVRIPLEKQ 276
Cdd:TIGR01186 240 DAERIAQRMNTGPITKTADKGPRSALQLMRD 270
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
4-228 |
4.90e-64 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 203.72 E-value: 4.90e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMV 81
Cdd:COG1122 1 IELENLSFSYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRElrRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNyalyP-----HKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVF 156
Cdd:COG1122 81 FQN----PddqlfAPTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVL 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1468311694 157 LFDEPLSNLDAKlrvtMRVKIAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIY 228
Cdd:COG1122 157 VLDEPTAGLDPR----GRRELLELLKRLNKEGK--TVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVF 222
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-218 |
2.11e-62 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 199.50 E-value: 2.11e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANV-SLRKVVKSYSNG---FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER 76
Cdd:COG1136 1 MSPLlELRNLTKSYGTGegeVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSEREL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 77 G------IAMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIV 150
Cdd:COG1136 81 ArlrrrhIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALV 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 151 RKPEVFLFDEPLSNLDAKLRvtMRVkIAQLHRTLKEEGspATMIYVTHDQtEALTLGDRICVLNHGKI 218
Cdd:COG1136 161 NRPKLILADEPTGNLDSKTG--EEV-LELLRELNRELG--TTIVMVTHDP-ELAARADRVIRLRDGRI 222
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
4-240 |
2.41e-62 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 199.82 E-value: 2.41e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RGI 78
Cdd:COG1127 6 IEVRNLTKSF-GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKElyelrRRI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHKTVFDNMAFGLKMQ-RCPKDEIKRRVEdaaEKLEITDLLE---RKPKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:COG1127 85 GMLFQGGALFDSLTVFENVAFPLREHtDLSEAEIRELVL---EKLELVGLPGaadKMPSELSGGMRKRVALARALALDPE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 155 VFLFDEPLSNLDAklrVTMRVkIAQLHRTLKEEgSPATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPkNK 234
Cdd:COG1127 162 ILLYDEPTAGLDP---ITSAV-IDELIRELRDE-LGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLASD-DP 235
|
....*.
gi 1468311694 235 FVASFI 240
Cdd:COG1127 236 WVRQFL 241
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
4-227 |
1.72e-61 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 197.59 E-value: 1.72e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLP-AKERgIAMV 81
Cdd:COG1131 1 IEVRGLTKRY-GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVlGEDVARDPAeVRRR-IGYV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:COG1131 79 PQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 162 LSNLDAKLRVTMRvkiaQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:COG1131 159 TSGLDPEARRELW----ELLRELAAEG--KTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
4-218 |
4.58e-61 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 196.04 E-value: 4.58e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RGI 78
Cdd:COG2884 2 IRFENVSKRYPGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREipylrRRI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:COG2884 82 GVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 159 DEPLSNLDAKlrvtMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:COG2884 162 DEPTGNLDPE----TSWEIMELLEEINRRG--TTVLIATHDLELVDRMPKRVLELEDGRL 215
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
5-217 |
2.57e-59 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 191.14 E-value: 2.57e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG--IAMV 81
Cdd:cd03225 1 ELKNLSFSYPDGARPAlDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRrkVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNyalyP-----HKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVF 156
Cdd:cd03225 81 FQN----PddqffGPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDIL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 157 LFDEPLSNLDAKlrvtMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:cd03225 157 LLDEPTAGLDPA----GRRELLELLKKLKAEG--KTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
23-222 |
4.36e-59 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 190.58 E-value: 4.36e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIqDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN------NLPAKERGIAMVFQNYALYPHKTVFDN 96
Cdd:cd03297 17 IDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFdsrkkiNLPPQQRKIGLVFQQYALFPHLNVREN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLKmqRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVK 176
Cdd:cd03297 96 LAFGLK--RKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPE 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1468311694 177 IAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVD 222
Cdd:cd03297 174 LKQIKKNLN-----IPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
4-232 |
5.28e-59 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 198.97 E-value: 5.28e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSY----SNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE---- 75
Cdd:COG1123 261 LEVRNLSKRYpvrgKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSlrel 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 -RGIAMVFQN--YALYPHKTVFDNMAFGLKMQR-CPKDEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIV 150
Cdd:COG1123 341 rRRVQMVFQDpySSLNPRMTVGDIIAEPLRLHGlLSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRVAIARALA 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 151 RKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEE-GSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:COG1123 421 LEPKLLILDEPTSALD----VSVQAQILNLLRDLQRElGL--TYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFA 494
|
...
gi 1468311694 230 YPK 232
Cdd:COG1123 495 NPQ 497
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
4-241 |
6.10e-59 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 190.98 E-value: 6.10e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN----NLPAKERGIA 79
Cdd:COG1126 2 IEIENLHKSF-GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTdskkDINKLRRKVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNYALYPHKTVFDNMAFGL-KMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:COG1126 81 MVFQQFNLFPHLTVLENVTLAPiKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 159 DEPLSNLDAK-----LRVtMrvkiaqlhRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKN 233
Cdd:COG1126 161 DEPTSALDPElvgevLDV-M--------RDLAKEGM--TMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQH 229
|
....*...
gi 1468311694 234 KFVASFIG 241
Cdd:COG1126 230 ERTRAFLS 237
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
4-219 |
8.79e-57 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 185.65 E-value: 8.79e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RGI 78
Cdd:COG3638 3 LELRNLSKRYPGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRAlrrlrRRI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHKTVFDNMAFG-------LK--MQRCPKDEiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAI 149
Cdd:COG3638 83 GMIFQQFNLVPRLSVLTNVLAGrlgrtstWRslLGLFPPED-RERALEALERVGLADKAYQRADQLSGGQQQRVAIARAL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 150 VRKPEVFLFDEPLSNLDAKL-RVTMRVkIAQLHRtlkEEGspATMIYVTHDQTEALTLGDRICVLNHGKIM 219
Cdd:COG3638 162 VQEPKLILADEPVASLDPKTaRQVMDL-LRRIAR---EDG--ITVVVNLHQVDLARRYADRIIGLRDGRVV 226
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
4-218 |
1.33e-56 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 185.39 E-value: 1.33e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG---FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGI 78
Cdd:COG1124 2 LEVRNLSVSYGQGgrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAfrRRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNY--ALYPHKTVFDNMAFGLKMQRcpKDEIKRRVEDAAEKLEIT-DLLERKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:COG1124 82 QMVFQDPyaSLHPRHTVDRILAEPLRIHG--LPDREERIAELLEQVGLPpSFLDRYPHQLSGGQRQRVAIARALILEPEL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 156 FLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEgSPATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:COG1124 160 LLLDEPTSALD----VSVQAEILNLLKDLREE-RGLTYLFVSHDLAVVAHLCDRVAVMQNGRI 217
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
4-227 |
4.89e-56 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 183.47 E-value: 4.89e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsnGFKAVH-GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RG 77
Cdd:cd03261 1 IELRGLTKSF--GGRTVLkGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAElyrlrRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 IAMVFQNYALYPHKTVFDNMAFGLKMQ-RCPKDEIKRRVedaAEKLE---ITDLLERKPKEMSGGQRQRVAVGRAIVRKP 153
Cdd:cd03261 79 MGMLFQSGALFDSLTVFENVAFPLREHtRLSEEEIREIV---LEKLEavgLRGAEDLYPAELSGGMKKRVALARALALDP 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 154 EVFLFDEPLSNLDAklrVTMRVkIAQLHRTLKEEgSPATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:cd03261 156 ELLLYDEPTAGLDP---IASGV-IDDLIRSLKKE-LGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
23-241 |
9.31e-56 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 182.65 E-value: 9.31e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQNYALYPHKTVFDNMAFGLK 102
Cdd:COG3840 18 FDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERPVSMLFQENNLFPHLTVAQNIGLGLR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 103 MQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVKIAQLHR 182
Cdd:COG3840 98 PGLKLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPALRQEMLDLVDELCR 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 183 TLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIG 241
Cdd:COG3840 178 ERG-----LTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLG 231
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
4-218 |
3.32e-55 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 180.42 E-value: 3.32e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNgFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN----NLPAKERGIA 79
Cdd:cd03262 1 IEIKNLHKSFGD-FHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTddkkNINELRQKVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNYALYPHKTVFDNMAFGL-KMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:cd03262 80 MVFQQFNLFPHLTVLENITLAPiKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLF 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 159 DEPLSNLDAKLrvtmrVK-IAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03262 160 DEPTSALDPEL-----VGeVLDVMKDLAEEG--MTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
23-227 |
8.15e-55 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 184.15 E-value: 8.15e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN------NLPAKERGIAMVFQNYALYPHKTVFDN 96
Cdd:COG4148 18 VDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQdsargiFLPPHRRRIGYVFQEARLFPHLSVRGN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLKmqRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVK 176
Cdd:COG4148 98 LLYGRK--RAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILPY 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 177 IAQLHRTLkeeGSPatMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:COG4148 176 LERLRDEL---DIP--ILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEV 221
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
4-240 |
4.16e-54 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 178.75 E-value: 4.16e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGfKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGI----A 79
Cdd:PRK09493 2 IEFKNVSKHFGPT-QVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIrqeaG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNYALYPHKTVFDNMAFG-LKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:PRK09493 81 MVFQQFYLFPHLTALENVMFGpLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 159 DEPLSNLDAKLrvtmRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVAS 238
Cdd:PRK09493 161 DEPTSALDPEL----RHEVLKVMQDLAEEG--MTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQE 234
|
..
gi 1468311694 239 FI 240
Cdd:PRK09493 235 FL 236
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
4-219 |
9.97e-54 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 177.31 E-value: 9.97e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG---FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG--- 77
Cdd:cd03257 2 LEVKNLSVSFPTGggsVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKirr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 --IAMVFQNY--ALYPHKTVFDNMAFGLKMQRCP--KDEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIV 150
Cdd:cd03257 82 keIQMVFQDPmsSLNPRMTIGEQIAEPLRIHGKLskKEARKEAVLLLLVGVGLpEEVLNRYPHELSGGQRQRVAIARALA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 151 RKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGSpATMIYVTHDQTEALTLGDRICVLNHGKIM 219
Cdd:cd03257 162 LNPKLLIADEPTSALD----VSVQAQILDLLKKLQEELG-LTLLFITHDLGVVAKIADRVAVMYAGKIV 225
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
4-339 |
1.19e-52 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 177.96 E-value: 1.19e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG---FKAVHGIDLDIQDGEfmVF--VGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--- 75
Cdd:COG1135 2 IELENLSKTFPTKggpVTALDDVSLTIEKGE--IFgiIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERElra 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 --RGIAMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVedaAEKLEITDLLERK---PKEMSGGQRQRVAVGRAIV 150
Cdd:COG1135 80 arRKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRV---AELLELVGLSDKAdayPSQLSGGQKQRVGIARALA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 151 RKPEVFLFDEPLSNLDAK-----LRVtmrvkIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPA 225
Cdd:COG1135 157 NNPKVLLCDEATSALDPEttrsiLDL-----LKDINRELG-----LTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVL 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 226 NIYNYPKNKFVASFIGS-----PSMNLIDAVIRKAGNDIVIEIDF-GKQVRIPlekqmnLLAQINKPvcFGIRPehimfa 299
Cdd:COG1135 227 DVFANPQSELTRRFLPTvlndeLPEELLARLREAAGGGRLVRLTFvGESADEP------LLSELARR--FGVDV------ 292
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1468311694 300 svedkeNILHGvltNIENMGNEK--NLYFNI-GARELIMRAVA 339
Cdd:COG1135 293 ------NILSG---GIEEIQGTPvgRLIVELeGDDAAIDAALA 326
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
4-217 |
1.57e-52 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 173.59 E-value: 1.57e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RGI 78
Cdd:TIGR02673 2 IEFHNVSKAYPGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRQlpllrRRI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:TIGR02673 82 GVVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 159 DEPLSNLDAklrvTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:TIGR02673 162 DEPTGNLDP----DLSERILDLLKRLNKRG--TTVIVATHDLSLVDRVAHRVIILDDGR 214
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-232 |
2.63e-52 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 181.25 E-value: 2.63e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANV-SLRKVVKSYSNG-FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDIT---TGEIYIGNTMVNNLPAKE 75
Cdd:COG1123 1 MTPLlEVRDLSVRYPGGdVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 RG--IAMVFQN--YALYPHkTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVR 151
Cdd:COG1123 81 RGrrIGMVFQDpmTQLNPV-TVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 152 KPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGSpATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYP 231
Cdd:COG1123 160 DPDLLIADEPTTALD----VTTQAEILDLLRELQRERG-TTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAP 234
|
.
gi 1468311694 232 K 232
Cdd:COG1123 235 Q 235
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
4-227 |
3.11e-52 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 173.14 E-value: 3.11e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDI-----TTGEIYIGNTMVNNLPAKE--- 75
Cdd:cd03260 1 IELRDLNVYY-GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDIYDLDVDVlel 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 -RGIAMVFQNYALYPhKTVFDNMAFGLKMQRC-PKDEIKRRVEDAAEKLEITDLLERK--PKEMSGGQRQRVAVGRAIVR 151
Cdd:cd03260 80 rRRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIkLKEELDERVEEALRKAALWDEVKDRlhALGLSGGQQQRLCLARALAN 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 152 KPEVFLFDEPLSNLDAklrvTMRVKIAQLHRTLKEEgspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:cd03260 159 EPEVLLLDEPTSALDP----ISTAKIEELIAELKKE---YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-213 |
2.59e-50 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 169.27 E-value: 2.59e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYSNGFKAVH---GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNlPAKERG 77
Cdd:COG4525 1 MSMLTVRHVSVRYPGGGQPQPalqDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTG-PGADRG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 IamVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFL 157
Cdd:COG4525 80 V--VFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 158 FDEPLSNLDAKLRVTMRVKIAQL-HRTLKeegspaTMIYVTHDQTEALTLGDRICVL 213
Cdd:COG4525 158 MDEPFGALDALTREQMQELLLDVwQRTGK------GVFLITHSVEEALFLATRLVVM 208
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
4-218 |
3.80e-49 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 164.89 E-value: 3.80e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RGI 78
Cdd:cd03292 1 IEFINVTKTYPNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAipylrRKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:cd03292 81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 159 DEPLSNLDAklrvTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03292 161 DEPTGNLDP----DTTWEIMNLLKKINKAG--TTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
5-218 |
1.28e-48 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 163.06 E-value: 1.28e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVvkSYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMV 81
Cdd:COG4619 2 ELEGL--SFRVGGKPIlSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEwrRQVAYV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPhKTVFDNMAFGLKMQRCPKDEikRRVEDAAEKLEIT-DLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:COG4619 80 PQEPALWG-GTVRDNLPFPFQLRERKFDR--ERALELLERLGLPpDILDKPVERLSGGERQRLALIRALLLQPDVLLLDE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 161 PLSNLDAKlrvtMRVKIAQL-HRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:COG4619 157 PTSALDPE----NTRRVEELlREYLAEEG--RAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
4-232 |
5.84e-48 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 162.37 E-value: 5.84e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG---FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE----- 75
Cdd:cd03258 2 IELKNVSKVFGDTggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKElrkar 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 RGIAMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:cd03258 82 RRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 156 FLFDEPLSNLDAKlrvTMRVKIAQLHRTLKEEGspATMIYVTHdQTEAL-TLGDRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:cd03258 162 LLCDEATSALDPE---TTQSILALLRDINRELG--LTIVLITH-EMEVVkRICDRVAVMEKGEVVEEGTVEEVFANPQ 233
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
4-229 |
7.61e-48 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 162.98 E-value: 7.61e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFK-AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIG--NTM-VNNLPAKERGIA 79
Cdd:TIGR04520 1 IEVENVSFSYPESEKpALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDglDTLdEENLWEIRKKVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNyalyPHK-----TVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:TIGR04520 81 MVFQN----PDNqfvgaTVEDDVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPD 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 155 VFLFDEPLSNLDAKLRVTMRVKIAQLHrtlKEEGspATMIYVTHDQTEALtLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:TIGR04520 157 IIILDEATSMLDPKGRKEVLETIRKLN---KEEG--ITVISITHDMEEAV-LADRVIVMNKGKIVAEGTPREIFS 225
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
4-225 |
7.66e-48 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 161.52 E-value: 7.66e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG-FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLPAKERGIAMV 81
Cdd:cd03263 1 LQIRNLTKTYKKGtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYInGYSIRTDRKAARQSLGYC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:cd03263 81 PQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEP 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 162 LSNLDAKLRvtmRvkiaQLHRTLKEEGSPATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPA 225
Cdd:cd03263 161 TSGLDPASR---R----AIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQ 217
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
4-227 |
1.30e-47 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 162.14 E-value: 1.30e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG--IAMV 81
Cdd:COG1120 2 LEAENLSVGY-GGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELArrIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFG----LKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFL 157
Cdd:COG1120 81 PQEPPAPFGLTVRELVALGryphLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1468311694 158 FDEPLSNLDAK--LRVtMRVkIAQLHRtlkEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:COG1120 161 LDEPTSHLDLAhqLEV-LEL-LRRLAR---ERG--RTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEV 225
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
6-227 |
1.79e-46 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 158.89 E-value: 1.79e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RGIAM 80
Cdd:cd03256 3 VENLSKTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKAlrqlrRQIGM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDN--------MAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRK 152
Cdd:cd03256 83 IFQQFNLIERLSVLENvlsgrlgrRSTWRSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALMQQ 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 153 PEVFLFDEPLSNLDAKL-RVTMRVkIAQLHRtlkEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:cd03256 163 PKLILADEPVASLDPASsRQVMDL-LKRINR---EEG--ITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
24-221 |
4.76e-46 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 156.95 E-value: 4.76e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 24 DLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQNYALYPHKTVFDNMAFGLKM 103
Cdd:TIGR01277 18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQRPVSMLFQENNLFAHLTVRQNIGLGLHP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 104 QRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVKIAQLHRT 183
Cdd:TIGR01277 98 GLKLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQLCSE 177
|
170 180 190
....*....|....*....|....*....|....*...
gi 1468311694 184 LKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQV 221
Cdd:TIGR01277 178 RQ-----RTLLMVTHHLSDARAIASQIAVVSQGKIKVV 210
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
6-232 |
2.45e-45 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 158.29 E-value: 2.45e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLED---ITTGEIYIGNTMVNNLPAKE----RG- 77
Cdd:COG0444 7 LKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPppgITSGEILFDGEDLLKLSEKElrkiRGr 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 -IAMVFQN-Y-ALYPHKTVFDNMAFGLKM-QRCPKDEIKRRVEDAAEKLEITD---LLERKPKEMSGGQRQRVAVGRAIV 150
Cdd:COG0444 87 eIQMIFQDpMtSLNPVMTVGDQIAEPLRIhGGLSKAEARERAIELLERVGLPDperRLDRYPHELSGGMRQRVMIARALA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 151 RKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEE-GSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:COG0444 167 LEPKLLIADEPTTALD----VTIQAQILNLLKDLQRElGL--AILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFE 240
|
...
gi 1468311694 230 YPK 232
Cdd:COG0444 241 NPR 243
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
20-204 |
3.14e-45 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 154.56 E-value: 3.14e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAG-LEDI--TTGEIYIGNTMVNNLPAKERGIAMVFQNYALYPHKTVFDN 96
Cdd:COG4136 17 LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGtLSPAfsASGEVLLNGRRLTALPAEQRRIGILFQDDLLFPHLSVGEN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLKmQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRvk 176
Cdd:COG4136 97 LAFALP-PTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAALRAQFR-- 173
|
170 180
....*....|....*....|....*...
gi 1468311694 177 iAQLHRTLKEEGSPATMiyVTHDQTEAL 204
Cdd:COG4136 174 -EFVFEQIRQRGIPALL--VTHDEEDAP 198
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
4-218 |
6.62e-45 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 153.80 E-value: 6.62e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsnGFKAVHgIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQ 83
Cdd:cd03298 1 VRLDKIRFSY--GEQPMH-FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSMLFQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLS 163
Cdd:cd03298 78 ENNLFAHLTVEQNVGLGLSPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 164 NLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03298 158 ALDPALRAEMLDLVLDLHAETK-----MTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
20-163 |
2.06e-44 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 150.49 E-value: 2.06e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVFQNYALYPHKTVFDNM 97
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSlrKEIGYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 98 AFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERK----PKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLS 163
Cdd:pfam00005 81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRPvgerPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
6-227 |
2.12e-44 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 153.47 E-value: 2.12e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAK-ERGIAMVFQN 84
Cdd:COG4555 4 VENLSKKY-GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREaRRQIGVLPDE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 85 YALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSN 164
Cdd:COG4555 83 RGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNG 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 165 LDAKLRVTMRvkiaQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:COG4555 163 LDVMARRLLR----EILRALKKEGK--TVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDEL 219
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
6-224 |
6.36e-44 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 152.52 E-value: 6.36e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYsnGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNlpAKERgIAMVFQN 84
Cdd:PRK11247 15 LNAVSKRY--GERTVlNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAE--ARED-TRLMFQD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 85 YALYPHKTVFDNMAFGLKMQRCPkdeikrrveDAAEKLEITDLLERK---PKEMSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:PRK11247 90 ARLLPWKKVIDNVGLGLKGQWRD---------AALQALAAVGLADRAnewPAALSGGQKQRVALARALIHRPGLLLLDEP 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 162 LSNLDAKLRVTMRVKIAQLHRtlkEEGspATMIYVTHDQTEALTLGDRICVLNHGKI---MQVDTP 224
Cdd:PRK11247 161 LGALDALTRIEMQDLIESLWQ---QHG--FTVLLVTHDVSEAVAMADRVLLIEEGKIgldLTVDLP 221
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
4-232 |
7.18e-44 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 152.99 E-value: 7.18e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG----FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE---- 75
Cdd:TIGR04521 1 IKLKNVSYIYQPGtpfeKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKlkdl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 -RGIAMVFQnyalYPHK-----TVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEIT-DLLERKPKEMSGGQRQRVAVGRA 148
Cdd:TIGR04521 81 rKKVGLVFQ----FPEHqlfeeTVYKDIAFGPKNLGLSEEEAEERVKEALELVGLDeEYLERSPFELSGGQMRRVAIAGV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 149 IVRKPEVFLFDEPLSNLDAKLRVTMRVKIAQLHrtlKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIY 228
Cdd:TIGR04521 157 LAMEPEVLILDEPTAGLDPKGRKEILDLFKRLH---KEKG--LTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVF 231
|
....
gi 1468311694 229 NYPK 232
Cdd:TIGR04521 232 SDVD 235
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
22-224 |
8.13e-44 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 151.46 E-value: 8.13e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNlPAKERGIamVFQNYALYPHKTVFDNMAFGL 101
Cdd:TIGR01184 3 GVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITE-PGPDRMV--VFQNYSLLPWLTVRENIALAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 102 K--MQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMR---VK 176
Cdd:TIGR01184 80 DrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQeelMQ 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 177 IAQLHRtlkeegspATMIYVTHDQTEALTLGDRICVLNH------GKIMQVDTP 224
Cdd:TIGR01184 160 IWEEHR--------VTVLMVTHDVDEALLLSDRVVMLTNgpaaniGQILEVPFP 205
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
4-218 |
8.72e-44 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 149.47 E-value: 8.72e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLPAKERGIAMVF 82
Cdd:cd03230 1 IEVRNLSKRY-GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVlGKDIKKEPEEVKRRIGYLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QNYALYPHKTVFDNMafglkmqrcpkdeikrrvedaaekleitdllerkpkEMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:cd03230 80 EEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPELLILDEPT 123
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 163 SNLDAKLRVTMRvkiaQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03230 124 SGLDPESRREFW----ELLRELKKEG--KTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
5-242 |
8.68e-43 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 151.88 E-value: 8.68e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RGIA 79
Cdd:PRK11153 6 NISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKElrkarRQIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFD 159
Cdd:PRK11153 86 MIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLLCD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 160 EPLSNLDAKlrvTMRV---KIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFV 236
Cdd:PRK11153 166 EATSALDPA---TTRSileLLKDINRELG-----LTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHPLT 237
|
....*.
gi 1468311694 237 ASFIGS 242
Cdd:PRK11153 238 REFIQS 243
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
5-232 |
2.49e-42 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 147.58 E-value: 2.49e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER---GIAMV 81
Cdd:cd03219 2 EVRGLTKRF-GGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIarlGIGRT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFGLKMQ----------RCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVR 151
Cdd:cd03219 81 FQIPRLFPELTVLENVMVAAQARtgsglllaraRREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALAT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 152 KPEVFLFDEPLsnldAKLRVTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYP 231
Cdd:cd03219 161 DPKLLLLDEPA----AGLNPEETEELAELIRELRERG--ITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNP 234
|
.
gi 1468311694 232 K 232
Cdd:cd03219 235 R 235
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
23-227 |
2.69e-42 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 151.03 E-value: 2.69e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNN------LPAKERGIAMVFQNYALYPHKTVFDN 96
Cdd:TIGR02142 16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDsrkgifLPPEKRRIGYVFQEARLFPHLSVRGN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLKmqRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMrvk 176
Cdd:TIGR02142 96 LRYGMK--RARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEI--- 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 177 IAQLHRTLKEEGSPatMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:TIGR02142 171 LPYLERLHAEFGIP--ILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEV 219
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
8-230 |
5.45e-42 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 147.06 E-value: 5.45e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 8 KVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RGIAMVF 82
Cdd:TIGR02315 6 NLSKVYPNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKlrklrRRIGMIF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QNYALYPHKTVFDNM---AFGLK------MQRCPKDEiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKP 153
Cdd:TIGR02315 86 QHYNLIERLTVLENVlhgRLGYKptwrslLGRFSEED-KERALSALERVGLADKAYQRADQLSGGQQQRVAIARALAQQP 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 154 EVFLFDEPLSNLDAKL-RVTMRVkiaqLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNY 230
Cdd:TIGR02315 165 DLILADEPIASLDPKTsKQVMDY----LKRINKEDG--ITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELDDE 236
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-227 |
7.02e-42 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 146.77 E-value: 7.02e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTmvnNLPAKERGIAM 80
Cdd:COG1121 4 MPAIELENLTVSY-GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGK---PPRRARRRIGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHK--TVFDNMAFGL----KMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:COG1121 80 VPQRAEVDWDFpiTVRDVVLMGRygrrGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPD 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 155 VFLFDEPLSNLDAKlrvtMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLN-----HGKIMQVDTPANI 227
Cdd:COG1121 160 LLLLDEPFAGVDAA----TEEALYELLRELRREG--KTILVVTHDLGAVREYFDRVLLLNrglvaHGPPEEVLTPENL 231
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
3-225 |
9.06e-42 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 155.38 E-value: 9.06e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 3 NVSLRKVVKSYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIA 79
Cdd:COG2274 473 DIELENVSFRYPGDSPPVlDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASlrRQIG 552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNYALYpHKTVFDNMAFGLKMqrcPKDEikrRVEDAAEKLEITDLLERKPK-------EM----SGGQRQRVAVGRA 148
Cdd:COG2274 553 VVLQDVFLF-SGTIRENITLGDPD---ATDE---EIIEAARLAGLHDFIEALPMgydtvvgEGgsnlSGGQRQRLAIARA 625
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 149 IVRKPEVFLFDEPLSNLDAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTHDqTEALTLGDRICVLNHGKIMQVDTPA 225
Cdd:COG2274 626 LLRNPRILILDEATSALDAETE-------AIILENLRRLLKGRTVIIIAHR-LSTIRLADRIIVLDKGRIVEDGTHE 694
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
3-240 |
1.17e-41 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 146.31 E-value: 1.17e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 3 NVSLRKVVKSYSNgFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN---NLPAKE---- 75
Cdd:COG4161 2 SIQLKNINCFYGS-HQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDfsqKPSEKAirll 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 -RGIAMVFQNYALYPHKTVFDNM-AFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKP 153
Cdd:COG4161 81 rQKVGMVFQQYNLWPHLTVMENLiEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 154 EVFLFDEPLSNLDAKlrVTmrVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTpANIYNYPKN 233
Cdd:COG4161 161 QVLLFDEPTAALDPE--IT--AQVVEIIRELSQTG--ITQVIVTHEVEFARKVASQVVYMEKGRIIEQGD-ASHFTQPQT 233
|
....*..
gi 1468311694 234 KFVASFI 240
Cdd:COG4161 234 EAFAHYL 240
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
19-239 |
1.87e-41 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 150.18 E-value: 1.87e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE------RGIAMVFQNYALYPHKT 92
Cdd:PRK10070 43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAElrevrrKKIAMVFQSFALMPHMT 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 93 VFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVT 172
Cdd:PRK10070 123 VLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTE 202
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 173 MRVKIAQLHRTLKEegspaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASF 239
Cdd:PRK10070 203 MQDELVKLQAKHQR-----TIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTF 264
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-241 |
2.07e-41 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 145.66 E-value: 2.07e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNN---LPAKERG 77
Cdd:PRK11264 1 MSAIEVKNLVKKF-HGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDTarsLSQQKGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 I-------AMVFQNYALYPHKTVFDNMAFG-LKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAI 149
Cdd:PRK11264 80 IrqlrqhvGFVFQNFNLFPHRTVLENIIEGpVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 150 VRKPEVFLFDEPLSNLDAKLRVTMRVKIaqlhRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:PRK11264 160 AMRPEVILFDEPTSALDPELVGEVLNTI----RQLAQEKR--TMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFA 233
|
250
....*....|....*.
gi 1468311694 230 YPKN----KFVASFIG 241
Cdd:PRK11264 234 DPQQprtrQFLEKFLL 249
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
4-229 |
1.76e-40 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 143.98 E-value: 1.76e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFK-AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN--NLPAKERGIAM 80
Cdd:PRK13632 8 IKVENVSFSYPNSENnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISkeNLKEIRKKIGI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNyalyPHK-----TVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:PRK13632 88 IFQN----PDNqfigaTVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEI 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 156 FLFDEPLSNLDAKLRVTMRVKIAQLHRTLKEegspaTMIYVTHDQTEALtLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:PRK13632 164 IIFDESTSMLDPKGKREIKKIMVDLRKTRKK-----TLISITHDMDEAI-LADKVIVFSEGKLIAQGKPKEILN 231
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1-218 |
2.11e-40 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 142.12 E-value: 2.11e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANV-SLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAK-ERGI 78
Cdd:cd03266 1 MITAdALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEaRRRL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHKTVFDNMAF-----GLKmqrcpKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKP 153
Cdd:cd03266 81 GFVSDSTGLYDRLTARENLEYfaglyGLK-----GDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDP 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 154 EVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03266 156 PVLLLDEPTTGLD----VMATRALREFIRQLRALGK--CILFSTHIMQEVERLCDRVVVLHRGRV 214
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
4-225 |
2.90e-40 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 149.52 E-value: 2.90e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMV 81
Cdd:COG4988 337 IELEDVSFSYPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASwrRQIAWV 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALyPHKTVFDNMAFGlkmQRCPKDEikrRVEDAAEKLEITDLLERKPKEM-----------SGGQRQRVAVGRAIV 150
Cdd:COG4988 417 PQNPYL-FAGTIRENLRLG---RPDASDE---ELEAALEAAGLDEFVAALPDGLdtplgeggrglSGGQAQRLALARALL 489
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 151 RKPEVFLFDEPLSNLDAKlrvTMRVKIAQLHRTLKEegspATMIYVTHDqTEALTLGDRICVLNHGKIMQVDTPA 225
Cdd:COG4988 490 RDAPLLLLDEPTAHLDAE---TEAEILQALRRLAKG----RTVILITHR-LALLAQADRILVLDDGRIVEQGTHE 556
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
4-217 |
5.85e-40 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 139.44 E-value: 5.85e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAM 80
Cdd:cd03228 1 IEFKNVSFSYPGRPKPVlKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESlrKNIAY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYpHKTVFDNmafglkmqrcpkdeikrrvedaaekleitdLLerkpkemSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:cd03228 81 VPQDPFLF-SGTIREN------------------------------IL-------SGGQRQRIAIARALLRDPPILILDE 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 161 PLSNLDAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTHDqTEALTLGDRICVLNHGK 217
Cdd:cd03228 123 ATSALDPETE-------ALILEALRALAKGKTVIVIAHR-LSTIRDADRIIVLDDGR 171
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
19-230 |
6.38e-40 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 142.85 E-value: 6.38e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVFQNyalyPHK----- 91
Cdd:PRK13635 22 ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDvrRQVGMVFQN----PDNqfvga 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 92 TVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRV 171
Cdd:PRK13635 98 TVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRR 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 172 TMRVKIaqlhRTLKEEGSpATMIYVTHDQTEALTlGDRICVLNHGKIMQVDTPANIYNY 230
Cdd:PRK13635 178 EVLETV----RQLKEQKG-ITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIFKS 230
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
4-232 |
7.53e-40 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 143.72 E-value: 7.53e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSY--SNGF--------KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPA 73
Cdd:COG4608 8 LEVRDLKKHFpvRGGLfgrtvgvvKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 74 KE-----RGIAMVFQN-YA-LYPHKTVFDNMAFGLKMQR-CPKDEIKRRVEDAAEK--LEiTDLLERKPKEMSGGQRQRV 143
Cdd:COG4608 88 RElrplrRRMQMVFQDpYAsLNPRMTVGDIIAEPLRIHGlASKAERRERVAELLELvgLR-PEHADRYPHEFSGGQRQRI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 144 AVGRAIVRKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEE-GspATMIYVTHDqtealtLG------DRICVLNHG 216
Cdd:COG4608 167 GIARALALNPKLIVCDEPVSALD----VSIQAQVLNLLEDLQDElG--LTYLFISHD------LSvvrhisDRVAVMYLG 234
|
250
....*....|....*.
gi 1468311694 217 KIMQVDTPANIYNYPK 232
Cdd:COG4608 235 KIVEIAPRDELYARPL 250
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
16-220 |
1.08e-38 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 138.68 E-value: 1.08e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 16 GFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNlPAKERGIamVFQNYALYPHKTVFD 95
Cdd:PRK11248 13 GKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEG-PGAERGV--VFQNEGLLPWRNVQD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 96 NMAFGLKMQRCPKDEikrRVEDAAEKLEITDLLE---RKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVT 172
Cdd:PRK11248 90 NVAFGLQLAGVEKMQ---RLEIAHQMLKKVGLEGaekRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQ 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1468311694 173 MRVKIAQLHRtlkEEGSPATMIyvTHDQTEALTLGDRICVL--NHGKIMQ 220
Cdd:PRK11248 167 MQTLLLKLWQ---ETGKQVLLI--THDIEEAVFMATELVLLspGPGRVVE 211
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
24-218 |
1.54e-38 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 137.79 E-value: 1.54e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 24 DLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGIAMVFQNYALYPHKTVFDNMAFGLKM 103
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNP 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 104 QRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVKIAQLHRT 183
Cdd:PRK10771 99 GLKLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVCQE 178
|
170 180 190
....*....|....*....|....*....|....*
gi 1468311694 184 LKeegspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:PRK10771 179 RQ-----LTLLMVSHSLEDAARIAPRSLVVADGRI 208
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
6-210 |
2.81e-38 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 136.21 E-value: 2.81e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYSNGfKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG------IA 79
Cdd:TIGR03608 1 LKNISKKFGDK-VILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASkfrrekLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFD 159
Cdd:TIGR03608 80 YLFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILAD 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 160 EPLSNLDAKlrvtMRVKIAQLHRTLKEEGSpaTMIYVTHDqTEALTLGDRI 210
Cdd:TIGR03608 160 EPTGSLDPK----NRDEVLDLLLELNDEGK--TIIIVTHD-PEVAKQADRV 203
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
3-225 |
5.04e-38 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 143.77 E-value: 5.04e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 3 NVSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAM 80
Cdd:COG1132 339 EIEFENVSFSYPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESlrRQIGV 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYpHKTVFDNMAFGlkmqrCPK--DEikrRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGR 147
Cdd:COG1132 419 VPQDTFLF-SGTIRENIRYG-----RPDatDE---EVEEAAKAAQAHEFIEALPDgydtvvgergvNLSGGQRQRIAIAR 489
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 148 AIVRKPEVFLFDEPLSNLDAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIMQVDTPA 225
Cdd:COG1132 490 ALLKDPPILILDEATSALDTETE-------ALIQEALERLMKGRTTIVIAH-RLSTIRNADRILVLDDGRIVEQGTHE 559
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
9-227 |
8.11e-38 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 135.58 E-value: 8.11e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 9 VVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAK-ERGIAMVFQNYAL 87
Cdd:cd03265 6 LVKKY-GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREvRRRIGIVFQDLSV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 YPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDA 167
Cdd:cd03265 85 DDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDP 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 168 KLRVTMRVKIAQLhrtLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:cd03265 165 QTRAHVWEYIEKL---KEEFG--MTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
5-217 |
1.12e-37 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 133.14 E-value: 1.12e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVF 82
Cdd:cd00267 1 EIENLSFRY-GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEElrRRIGYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QnyalyphktvfdnmafglkmqrcpkdeikrrvedaaekleitdllerkpkeMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:cd00267 80 Q---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPT 108
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 163 SNLDaklrVTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:cd00267 109 SGLD----PASRERLLELLRELAEEG--RTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
13-240 |
1.27e-37 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 135.93 E-value: 1.27e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 13 YSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDI-----TTGEIYIGNTMVN----NLPAKERGIAMVFQ 83
Cdd:COG1117 20 YYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLipgarVEGEILLDGEDIYdpdvDVVELRRRVGMVFQ 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYPhKTVFDNMAFGLKMQ-RCPKDEIKRRVEDAAEKL----EITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:COG1117 100 KPNPFP-KSIYDNVAYGLRLHgIKSKSELDEIVEESLRKAalwdEVKDRLKKSALGLSGGQQQRLCIARALAVEPEVLLM 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 159 DEPLSNLD--AklrvTMrvKIAQLHRTLKEEgspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFV 236
Cdd:COG1117 179 DEPTSALDpiS----TA--KIEELILELKKD---YTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIFTNPKDKRT 249
|
....
gi 1468311694 237 ASFI 240
Cdd:COG1117 250 EDYI 253
|
|
| ectoine_ehuA |
TIGR03005 |
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ... |
4-242 |
2.12e-37 |
|
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of a conserved four gene ABC transporter operon found next to ectoine unilization operons and ectoine biosynthesis operons. Ectoine is a compatible solute that protects enzymes from high osmolarity. It is released by some species in response to hypoosmotic shock, and it is taken up by a number of bacteria as a compatible solute or for consumption. This family shows strong sequence similiarity to a number of amino acid ABC transporter ATP-binding proteins.
Pssm-ID: 132050 [Multi-domain] Cd Length: 252 Bit Score: 135.34 E-value: 2.12e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNgFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNN--------LPAKE 75
Cdd:TIGR03005 1 VRFSDVTKRFGI-LTVLDGLNFSVAAGEKVALIGPSGSGKSTILRILMTLEPIDEGQIQVEGEQLYHmpgrngplVPADE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 R-------GIAMVFQNYALYPHKTVFDNMAFG-LKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGR 147
Cdd:TIGR03005 80 KhlrqmrnKIGMVFQSFNLFPHKTVLDNVTEApVLVLGMARAEAEKRAMELLDMVGLADKADHMPAQLSGGQQQRVAIAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 148 AIVRKPEVFLFDEPLSNLDAKLrvtmRVKIAQLHRTLKEEgSPATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:TIGR03005 160 ALAMRPKVMLFDEVTSALDPEL----VGEVLNVIRRLASE-HDLTMLLVTHEMGFAREFADRVCFFDKGRIVEQGKPDEI 234
|
250
....*....|....*
gi 1468311694 228 YNYPKNKFVASFIGS 242
Cdd:TIGR03005 235 FRQPKEERTREFLSK 249
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
5-218 |
3.31e-37 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 132.56 E-value: 3.31e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG--IAMVF 82
Cdd:cd03214 1 EVENLSVGY-GGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELArkIAYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QnyalyphktvfdnmafglkmqrcpkdeikrrvedAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:cd03214 80 Q----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPT 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 163 SNLDaklrVTMRVKIAQLHRTLKEEGSpATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03214 126 SHLD----IAHQIELLELLRRLARERG-KTVVMVLHDLNLAARYADRVILLKDGRI 176
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
5-227 |
6.67e-37 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 132.94 E-value: 6.67e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYSnGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER---GIAMV 81
Cdd:cd03224 2 EVENLNAGYG-KSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERaraGIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFGLkmQRCPKDEIKRRVEDAAE---KLEitDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:cd03224 81 PEGRRIFPELTVEENLLLGA--YARRRAKRKARLERVYElfpRLK--ERRKQLAGTLSGGEQQMLAIARALMSRPKLLLL 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 159 DEPLSNLDAKLrvtmrVK-IAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:cd03224 157 DEPSEGLAPKI-----VEeIFEAIRELRDEG--VTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
21-242 |
1.49e-36 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 133.39 E-value: 1.49e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 21 HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMV--------NNLPAKER-------GIAMVFQNY 85
Cdd:COG4598 25 KGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIrlkpdrdgELVPADRRqlqrirtRLGMVFQSF 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 86 ALYPHKTVFDNMAFG-LKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSN 164
Cdd:COG4598 105 NLWSHMTVLENVIEApVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAIARALAMEPEVMLFDEPTSA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 165 LDAK-----LRVtMrvkiaqlhRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASF 239
Cdd:COG4598 185 LDPElvgevLKV-M--------RDLAEEG--RTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGNPKSERLRQF 253
|
...
gi 1468311694 240 IGS 242
Cdd:COG4598 254 LSS 256
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
4-240 |
1.87e-36 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 132.45 E-value: 1.87e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGfKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN---NLPAKE----- 75
Cdd:PRK11124 3 IQLNGINCFYGAH-QALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDfskTPSDKAirelr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 RGIAMVFQNYALYPHKTVFDNMAFG-LKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:PRK11124 82 RNVGMVFQQYNLWPHLTVQQNLIEApCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQ 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 155 VFLFDEPLSNLDAKLRVTMrVKIAqlhRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTpANIYNYPKNK 234
Cdd:PRK11124 162 VLLFDEPTAALDPEITAQI-VSII---RELAETG--ITQVIVTHEVEVARKTASRVVYMENGHIVEQGD-ASCFTQPQTE 234
|
....*.
gi 1468311694 235 FVASFI 240
Cdd:PRK11124 235 AFKNYL 240
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
12-220 |
1.99e-36 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 131.50 E-value: 1.99e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 12 SYSNgFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIyignTMVNNLPAKERG-IAMVFQNYAL--- 87
Cdd:cd03235 8 SYGG-HPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSI----RVFGKPLEKERKrIGYVPQRRSIdrd 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 YPhKTVFDNMAFGL----KMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLS 163
Cdd:cd03235 83 FP-ISVRDVVLMGLyghkGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 164 NLDAKlrvtMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQ 220
Cdd:cd03235 162 GVDPK----TQEDIYELLRELRREG--MTILVVTHDLGLVLEYFDRVLLLNRTVVAS 212
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
4-225 |
2.07e-36 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 132.17 E-value: 2.07e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAV---HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLP----AKER 76
Cdd:COG4181 9 IELRGLTKTVGTGAGELtilKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDedarARLR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 77 G--IAMVFQNYALYPHKTVFDNMAFGLKMQRcpKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:COG4181 89 ArhVGFVFQSFQLLPTLTALENVMLPLELAG--RRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPA 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 155 VFLFDEPLSNLDAKlrvTmRVKIAQLHRTLKEEgSPATMIYVTHDQTEALtLGDRICVLNHGKIMQVDTPA 225
Cdd:COG4181 167 ILFADEPTGNLDAA---T-GEQIIDLLFELNRE-RGTTLVLVTHDPALAA-RCDRVLRLRAGRLVEDTAAT 231
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
5-218 |
2.56e-36 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 130.84 E-value: 2.56e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNtmvNNLPAKER--GIAMVF 82
Cdd:cd03226 1 RIENISFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNG---KPIKAKERrkSIGYVM 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QN--YALYpHKTVFDNMAFGLKmqrcPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:cd03226 78 QDvdYQLF-TDSVREELLLGLK----ELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDE 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 161 PLSNLDAKlrvTMRvKIAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03226 153 PTSGLDYK---NME-RVGELIRELAAQGK--AVIVITHDYEFLAKVCDRVLLLANGAI 204
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
4-218 |
2.80e-36 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 131.54 E-value: 2.80e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RGI 78
Cdd:PRK10908 2 IRFEHVSKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREvpflrRQI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:PRK10908 82 GMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 159 DEPLSNLDAKLrvtmRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:PRK10908 162 DEPTGNLDDAL----SEGILRLFEEFNRVG--VTVLMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
4-226 |
8.76e-36 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 137.20 E-value: 8.76e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSN-GFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAM 80
Cdd:COG4987 334 LELEDVSFRYPGaGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDlrRRIAV 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYpHKTVFDNMAFGlkmqrCPK--DEikrRVEDAAEKLEITDLLERKPK-------E----MSGGQRQRVAVGR 147
Cdd:COG4987 414 VPQRPHLF-DTTLRENLRLA-----RPDatDE---ELWAALERVGLGDWLAALPDgldtwlgEggrrLSGGERRRLALAR 484
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 148 AIVRKPEVFLFDEPLSNLDAklrVTMRvkiaQLHRTLKEEGSPATMIYVTHDQTeALTLGDRICVLNHGKIMQVDTPAN 226
Cdd:COG4987 485 ALLRDAPILLLDEPTEGLDA---ATEQ----ALLADLLEALAGRTVLLITHRLA-GLERMDRILVLEDGRIVEQGTHEE 555
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
4-264 |
3.18e-35 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 130.61 E-value: 3.18e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNgFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNN--------LPAkE 75
Cdd:COG4152 2 LELKGLTKRFGD-KTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPedrrrigyLPE-E 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 RGiamvfqnyaLYPHKTVFDNMAF-----GLkmqrcPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIV 150
Cdd:COG4152 80 RG---------LYPKMKVGEQLVYlarlkGL-----SKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 151 RKPEVFLFDEPLSNLDAklrVTMRVkIAQLHRTLKEEGspATMIYVTH--DQTEALTlgDRICVLNHGKIMQVDTPANIY 228
Cdd:COG4152 146 HDPELLILDEPFSGLDP---VNVEL-LKDVIRELAAKG--TTVIFSSHqmELVEELC--DRIVIINKGRKVLSGSVDEIR 217
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1468311694 229 N-YPKNKFVASFIGSPSMnLID----AVIRKAGNDIVIEID 264
Cdd:COG4152 218 RqFGRNTLRLEADGDAGW-LRAlpgvTVVEEDGDGAELKLE 257
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
18-229 |
3.76e-35 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 130.17 E-value: 3.76e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN----NLPAKERGIAMVFQ--NYALYpHK 91
Cdd:PRK13637 21 KALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITdkkvKLSDIRKKVGLVFQypEYQLF-EE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 92 TVFDNMAFGLKMQRCPKDEIKRRVEDAAE--KLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKL 169
Cdd:PRK13637 100 TIEKDIAFGPINLGLSEEEIENRVKRAMNivGLDYEDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKG 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 170 RVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:PRK13637 180 RDEILNKIKELHKEYN-----MTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFK 234
|
|
| LolD_lipo_ex |
TIGR02211 |
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ... |
7-218 |
3.97e-35 |
|
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 128.24 E-value: 3.97e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 7 RKVVKSYSNGFKAV---HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG------ 77
Cdd:TIGR02211 5 ENLGKRYQEGKLDTrvlKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLSSNERAklrnkk 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 IAMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFL 157
Cdd:TIGR02211 85 LGFIYQFHHLLPDFTALENVAMPLLIGKKSVKEAKERAYEMLEKVGLEHRINHRPSELSGGERQRVAIARALVNQPSLVL 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 158 FDEPLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLgDRICVLNHGKI 218
Cdd:TIGR02211 165 ADEPTGNLDNNNAKIIFDLMLELNRELN-----TSFLVVTHDLELAKKL-DRVLEMKDGQL 219
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-240 |
8.64e-35 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 128.49 E-value: 8.64e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYSNgFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGL-----EDITTGEIYIGNTMVNNLPAKE 75
Cdd:PRK14247 1 MNKIEIRDLKVSFGQ-VEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIFKMDVIE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 --RGIAMVFQNYALYPHKTVFDNMAFGLKMQRCPKD--EIKRRVEDAAEKL----EITDLLERKPKEMSGGQRQRVAVGR 147
Cdd:PRK14247 80 lrRRVQMVFQIPNPIPNLSIFENVALGLKLNRLVKSkkELQERVRWALEKAqlwdEVKDRLDAPAGKLSGGQQQRLCIAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 148 AIVRKPEVFLFDEPLSNLDAKlrvtMRVKIAQLHRTLKEEgspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:PRK14247 160 ALAFQPEVLLADEPTANLDPE----NTAKIESLFLELKKD---MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREV 232
|
250
....*....|...
gi 1468311694 228 YNYPKNKFVASFI 240
Cdd:PRK14247 233 FTNPRHELTEKYV 245
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
20-224 |
1.69e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 128.31 E-value: 1.69e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMV--NNLPAKERGIAMVFQNyalyPHK-----T 92
Cdd:PRK13650 23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLteENVWDIRHKIGMVFQN----PDNqfvgaT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 93 VFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVt 172
Cdd:PRK13650 99 VEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRL- 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 173 mrvkiaQLHRTLKE--EGSPATMIYVTHDQTEaLTLGDRICVLNHGKIMQVDTP 224
Cdd:PRK13650 178 ------ELIKTIKGirDDYQMTVISITHDLDE-VALSDRVLVMKNGQVESTSTP 224
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
18-218 |
2.15e-34 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 126.24 E-value: 2.15e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNnlPAKERGIAMVFQNYALYPHKTVFDNM 97
Cdd:cd03269 14 TALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLD--IAARNRIGYLPEERGLYPKMKVIDQL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 98 AFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVKI 177
Cdd:cd03269 92 VYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVI 171
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1468311694 178 aqlhRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03269 172 ----RELARAGK--TVILSTHQMELVEELCDRVLLLNKGRA 206
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
3-218 |
3.06e-34 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 125.78 E-value: 3.06e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 3 NVSLRKVVKSYSNG-FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIA 79
Cdd:cd03245 2 RIEFRNVSFSYPNQeIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADlrRNIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNYALYpHKTVFDNMAFGlkmqrCP--KDEikrRVEDAAEKLEITDLLERKPKEM-----------SGGQRQRVAVG 146
Cdd:cd03245 82 YVPQDVTLF-YGTLRDNITLG-----APlaDDE---RILRAAELAGVTDFVNKHPNGLdlqigergrglSGGQRQAVALA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1468311694 147 RAIVRKPEVFLFDEPLSNLDakLRVTMRVKiaqlHRtLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKI 218
Cdd:cd03245 153 RALLNDPPILLLDEPTSAMD--MNSEERLK----ER-LRQLLGDKTLIIITH-RPSLLDLVDRIIVMDSGRI 216
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
6-232 |
4.40e-34 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 132.12 E-value: 4.40e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSysngFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDiTTGEIYIGNTMVNNLPAKE-----RGIAM 80
Cdd:COG4172 292 FRRTVGH----VKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDGLSRRAlrplrRRMQV 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQN-YA-LYPHKTVFDNMAFGLKMQRCP--KDEIKRRVEDAAEKLEIT-DLLERKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:COG4172 367 VFQDpFGsLSPRMTVGQIIAEGLRVHGPGlsAAERRARVAEALEEVGLDpAARHRYPHEFSGGQRQRIAIARALILEPKL 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 156 FLFDEPLSNLDaklrVTMRVKIAQLHRTL-KEEGspATMIYVTHDQT--EALTlgDRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:COG4172 447 LVLDEPTSALD----VSVQAQILDLLRDLqREHG--LAYLFISHDLAvvRALA--HRVMVMKDGKVVEQGPTEQVFDAPQ 518
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
21-209 |
3.21e-33 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 122.97 E-value: 3.21e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 21 HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG-IAMVFQNYALYPHKTVFDNMAF 99
Cdd:COG4133 19 SGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRRrLAYLGHADGLKPELTVRENLRF 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 100 GLKMQRCPKDEikRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKlrvtMRVKIAQ 179
Cdd:COG4133 99 WAALYGLRADR--EAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAA----GVALLAE 172
|
170 180 190
....*....|....*....|....*....|....*
gi 1468311694 180 LHRTLKEEGspATMIYVTHDQTEA-----LTLGDR 209
Cdd:COG4133 173 LIAAHLARG--GAVLLTTHQPLELaaarvLDLGDF 205
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
20-240 |
4.89e-33 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 123.80 E-value: 4.89e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITT-----GEIYIGNTMVNNLPAK----ERGIAMVFQNYALYPH 90
Cdd:PRK14267 20 IKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNEearveGEVRLFGRNIYSPDVDpievRREVGMVFQYPNPFPH 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 91 KTVFDNMAFGLKMQRC--PKDEIKRRVEDAAEKL----EITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSN 164
Cdd:PRK14267 100 LTIYDNVAIGVKLNGLvkSKKELDERVEWALKKAalwdEVKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTAN 179
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 165 LDAklrVTMRvKIAQLHRTLKEEgspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFI 240
Cdd:PRK14267 180 IDP---VGTA-KIEELLFELKKE---YTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHELTEKYV 248
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
4-218 |
6.57e-33 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 120.61 E-value: 6.57e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSnGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNL-P--AKERGIAM 80
Cdd:cd03216 1 LELRGITKRFG-GVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFAsPrdARRAGIAM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQnyalyphktvfdnmafglkmqrcpkdeikrrvedaaekleitdllerkpkeMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:cd03216 80 VYQ---------------------------------------------------LSVGERQMVEIARALARNARLLILDE 108
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 161 PLSNLDAKLRVTMrvkIAQLHRtLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03216 109 PTAALTPAEVERL---FKVIRR-LRAQG--VAVIFISHRLDEVFEIADRVTVLRDGRV 160
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
3-219 |
2.08e-32 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 128.45 E-value: 2.08e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 3 NVSLRKVVKSYSN-GFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIA 79
Cdd:TIGR03375 463 EIEFRNVSFAYPGqETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPADlrRNIG 542
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNYALYpHKTVFDNMAFGlkmQRCPKDEikrRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRA 148
Cdd:TIGR03375 543 YVPQDPRLF-YGTLRDNIALG---APYADDE---EILRAAELAGVTEFVRRHPDgldmqigergrSLSGGQRQAVALARA 615
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 149 IVRKPEVFLFDEPLSNLDAklRVTMRVKiaqlhRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIM 219
Cdd:TIGR03375 616 LLRDPPILLLDEPTSAMDN--RSEERFK-----DRLKRWLAGKTLVLVTH-RTSLLDLVDRIIVMDNGRIV 678
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
4-213 |
3.44e-32 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 126.29 E-value: 3.44e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSnGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLP--AKERGIAM 80
Cdd:COG1129 5 LEMRGISKSFG-GVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLdGEPVRFRSPrdAQAAGIAI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGLKMQRCP---KDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFL 157
Cdd:COG1129 84 IHQELNLVPNLSVAENIFLGREPRRGGlidWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDARVLI 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 158 FDEPLSNLDAKlrvtmrvKIAQLH---RTLKEEGspATMIYVTHDQTEALTLGDRICVL 213
Cdd:COG1129 164 LDEPTASLTER-------EVERLFriiRRLKAQG--VAIIYISHRLDEVFEIADRVTVL 213
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
18-227 |
7.16e-32 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 125.69 E-value: 7.16e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIY--IGNTMVN--NLPAKERG-----IAMVFQNYALY 88
Cdd:TIGR03269 298 KAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNvrVGDEWVDmtKPGPDGRGrakryIGILHQEYDLY 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 89 PHKTVFDNM--AFGLKMqrcPKDEIKRRV----------EDAAEkleitDLLERKPKEMSGGQRQRVAVGRAIVRKPEVF 156
Cdd:TIGR03269 378 PHRTVLDNLteAIGLEL---PDELARMKAvitlkmvgfdEEKAE-----EILDKYPDELSEGERHRVALAQVLIKEPRIV 449
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 157 LFDEPLSNLDAKLRVTMRVKIAQLHRTLKEegspaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:TIGR03269 450 ILDEPTGTMDPITKVDVTHSILKAREEMEQ-----TFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEI 515
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
4-218 |
1.03e-31 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 118.83 E-value: 1.03e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGfKAVHGIDLDIQDGEFmVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG-IAMVF 82
Cdd:cd03264 1 LQLENLTKRYGKK-RALDGVSLTLGPGMY-GLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRrIGYLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:cd03264 79 QEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPT 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 163 SNLDAKLRVTMRvkiaqlhRTLKEEGSPATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03264 159 AGLDPEERIRFR-------NLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKL 207
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
4-227 |
1.09e-31 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 120.19 E-value: 1.09e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGfKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMV 81
Cdd:COG4604 2 IEIKNVSKRYGGK-VVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRElaKRLAIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFGlkmqRCP------KDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:COG4604 81 RQENHINSRLTVRELVAFG----RFPyskgrlTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDY 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1468311694 156 FLFDEPLSNLDAKLRVTMrvkIAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:COG4604 157 VLLDEPLNNLDMKHSVQM---MKLLRRLADELGK--TVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI 223
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
19-213 |
2.94e-31 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 117.33 E-value: 2.94e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIgntmvnnlpAKERGIAMVFQNYAL---YPhKTVFD 95
Cdd:NF040873 7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRR---------AGGARVAYVPQRSEVpdsLP-LTVRD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 96 NMAFGL----KMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRV 171
Cdd:NF040873 77 LVAMGRwarrGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRE 156
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1468311694 172 TMRVKIAQLHRtlkeEGspATMIYVTHDQtEALTLGDRICVL 213
Cdd:NF040873 157 RIIALLAEEHA----RG--ATVVVVTHDL-ELVRRADPCVLL 191
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
23-229 |
5.32e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 118.70 E-value: 5.32e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN--NLPAKERGIAMVFQNyalyPHK-----TVFD 95
Cdd:PRK13648 28 VSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITddNFEKLRKHIGIVFQN----PDNqfvgsIVKY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 96 NMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMrv 175
Cdd:PRK13648 104 DVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNL-- 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 176 kiAQLHRTLKEEGSpATMIYVTHDQTEALTlGDRICVLNHGKIMQVDTPANIYN 229
Cdd:PRK13648 182 --LDLVRKVKSEHN-ITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFD 231
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
4-245 |
6.81e-31 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 118.55 E-value: 6.81e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMV---NNLPAKERGIAM 80
Cdd:PRK13644 2 IRLENVSYSYPDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTgdfSKLQGIRKLVGI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQN-YALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFD 159
Cdd:PRK13644 82 VFQNpETQFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 160 EPLSNLDAKLRVTMRVKIAQLHRTLKeegspaTMIYVTHDqTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVAsf 239
Cdd:PRK13644 162 EVTSMLDPDSGIAVLERIKKLHEKGK------TIVYITHN-LEELHDADRIIVMDRGKIVLEGEPENVLSDVSLQTLG-- 232
|
....*.
gi 1468311694 240 IGSPSM 245
Cdd:PRK13644 233 LTPPSL 238
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
22-240 |
9.37e-31 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 117.76 E-value: 9.37e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGN---TMV------------NNLPAKERGIAMVFQNYA 86
Cdd:PRK10619 23 GVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGqtiNLVrdkdgqlkvadkNQLRLLRTRLTMVFQHFN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 87 LYPHKTVFDN-MAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERK-PKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSN 164
Cdd:PRK10619 103 LWSHMTVLENvMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKyPVHLSGGQQQRVSIARALAMEPEVLLFDEPTSA 182
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 165 LDAKLrVTMRVKIAQlhrTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFI 240
Cdd:PRK10619 183 LDPEL-VGEVLRIMQ---QLAEEGK--TMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFL 252
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
4-218 |
3.18e-30 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 116.34 E-value: 3.18e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGF----KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG-- 77
Cdd:COG1101 2 LELKNLSKTFNPGTvnekRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAky 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 IAMVFQNYAL--YPHKTVFDNMA--------FGLKMQRcpkdeIKRRVEDAAEKLEITDL-LERKPKE----MSGGQRQR 142
Cdd:COG1101 82 IGRVFQDPMMgtAPSMTIEENLAlayrrgkrRGLRRGL-----TKKRRELFRELLATLGLgLENRLDTkvglLSGGQRQA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 143 VAVGRAIVRKPEVFLFDEPLSNLDAK-----LRVTMRVkIAQLHRTlkeegspaTMIyVTHDQTEALTLGDRICVLNHGK 217
Cdd:COG1101 157 LSLLMATLTKPKLLLLDEHTAALDPKtaalvLELTEKI-VEENNLT--------TLM-VTHNMEQALDYGNRLIMMHEGR 226
|
.
gi 1468311694 218 I 218
Cdd:COG1101 227 I 227
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
5-225 |
3.47e-30 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 115.46 E-value: 3.47e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER---GIAMV 81
Cdd:COG0410 5 EVENLHAGY-GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIarlGIGYV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFGLkMQRCPKDEIKRRVEDAAE---KLEitDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:COG0410 84 PEGRRIFPSLTVEENLLLGA-YARRDRAEVRADLERVYElfpRLK--ERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 159 DEP---LSNLdaklrvtMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPA 225
Cdd:COG0410 161 DEPslgLAPL-------IVEEIFEIIRRLNREG--VTILLVEQNARFALEIADRAYVLERGRIVLEGTAA 221
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
34-231 |
1.00e-29 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 117.28 E-value: 1.00e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 34 VFvGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN------NLPAKERGIAMVFQNYALYPHKTVFDNMAFGLKmqrcP 107
Cdd:PRK11144 29 IF-GRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFdaekgiCLPPEKRRIGYVFQDARLFPHYKVRGNLRYGMA----K 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 108 KDeiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRvtmRVKIAQLHRTLKEE 187
Cdd:PRK11144 104 SM--VAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRK---RELLPYLERLAREI 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1468311694 188 GSPatMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYP 231
Cdd:PRK11144 179 NIP--ILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASS 220
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
4-218 |
1.07e-29 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 113.47 E-value: 1.07e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGfKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLPAKERgIAMVF 82
Cdd:cd03268 1 LKTNDLTKTYGKK-RVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFdGKSYQKNIEALRR-IGALI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QNYALYPHKTVFDNMAFGLKMQRCPkdeiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:cd03268 79 EAPGFYPNLTARENLRLLARLLGIR----KKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPT 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 163 SNLDAKLRVTMRvkiaQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03268 155 NGLDPDGIKELR----ELILSLRDQG--ITVLISSHLLSEIQKVADRIGIINKGKL 204
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
13-240 |
1.31e-29 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 114.88 E-value: 1.31e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 13 YSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDI-----TTGEIYIGNtmvNNLPAKE-------RGIAM 80
Cdd:PRK14243 19 YYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLipgfrVEGKVTFHG---KNLYAPDvdpvevrRRIGM 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPhKTVFDNMAFGLKMQ--RCPKDE-IKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFL 157
Cdd:PRK14243 96 VFQKPNPFP-KSIYDNIAYGARINgyKGDMDElVERSLRQAALWDEVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEVIL 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 158 FDEPLSNLDAklrvTMRVKIAQLHRTLKEEgspATMIYVTHDQTEALTLGDRICVLN---------HGKIMQVDTPANIY 228
Cdd:PRK14243 175 MDEPCSALDP----ISTLRIEELMHELKEQ---YTIIIVTHNMQQAARVSDMTAFFNveltegggrYGYLVEFDRTEKIF 247
|
250
....*....|..
gi 1468311694 229 NYPKNKFVASFI 240
Cdd:PRK14243 248 NSPQQQATRDYV 259
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
4-218 |
2.12e-29 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 113.48 E-value: 2.12e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNN--LPAKERGIAMV 81
Cdd:cd03253 1 IEFENVTFAYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREvtLDSLRRAIGVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYpHKTVFDNMAFGlkmqrCPK--DEikrRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRA 148
Cdd:cd03253 81 PQDTVLF-NDTIGYNIRYG-----RPDatDE---EVIEAAKAAQIHDKIMRFPDgydtivgerglKLSGGEKQRVAIARA 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 149 IVRKPEVFLFDEPLSNLDAklrVTMRvkiaQLHRTLKEEGSPATMIYVTHDQTEALTlGDRICVLNHGKI 218
Cdd:cd03253 152 ILKNPPILLLDEATSALDT---HTER----EIQAALRDVSKGRTTIVIAHRLSTIVN-ADKIIVLKDGRI 213
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
4-220 |
2.59e-29 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 114.13 E-value: 2.59e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG-------FKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE 75
Cdd:TIGR02769 3 LEVRDVTHTYRTGglfgakqRAPVlTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDRKQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 -----RGIAMVFQNY--ALYPHKTVFDNMAFGLK-MQRCPKDEIKRRvedAAEKLEITDL----LERKPKEMSGGQRQRV 143
Cdd:TIGR02769 83 rrafrRDVQLVFQDSpsAVNPRMTVRQIIGEPLRhLTSLDESEQKAR---IAELLDMVGLrsedADKLPRQLSGGQLQRI 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 144 AVGRAIVRKPEVFLFDEPLSNLDAKLRVTmrvkIAQLHRTLKEEGSPAtMIYVTHDQTEALTLGDRICVLNHGKIMQ 220
Cdd:TIGR02769 160 NIARALAVKPKLIVLDEAVSNLDMVLQAV----ILELLRKLQQAFGTA-YLFITHDLRLVQSFCQRVAVMDKGQIVE 231
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
20-228 |
4.14e-29 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 114.03 E-value: 4.14e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN--NLPAKERGIAMVFQNY-ALYPHKTVFDN 96
Cdd:PRK13642 23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTaeNVWNLRRKIGMVFQNPdNQFVGATVEDD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAklrvTMRVK 176
Cdd:PRK13642 103 VAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDP----TGRQE 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1468311694 177 IAQLHRTLKEEgSPATMIYVTHDQTEALTlGDRICVLNHGKIMQVDTPANIY 228
Cdd:PRK13642 179 IMRVIHEIKEK-YQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELF 228
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
18-232 |
6.40e-29 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 114.42 E-value: 6.40e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEI-YIGNTMVNNLPAKERG----IAMVFQN--YALYPH 90
Cdd:PRK15079 35 KAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVaWLGKDLLGMKDDEWRAvrsdIQMIFQDplASLNPR 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 91 KTVFDNMAFGLKMQR--CPKDEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDa 167
Cdd:PRK15079 115 MTIGEIIAEPLRTYHpkLSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALD- 193
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 168 klrVTMRVKIAQLHRTL-KEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:PRK15079 194 ---VSIQAQVVNLLQQLqREMG--LSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPL 254
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
7-232 |
7.65e-29 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 113.25 E-value: 7.65e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 7 RKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNN---LPAKERGIAMVF 82
Cdd:PRK13639 5 RDLKYSYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIkGEPIKYDkksLLEVRKTVGIVF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QN-----YAlyphKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFL 157
Cdd:PRK13639 85 QNpddqlFA----PTVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 158 FDEPLSNLDAKlrvtMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:PRK13639 161 LDEPTSGLDPM----GASQIMKLLYDLNKEG--ITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDIE 229
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
4-218 |
1.07e-28 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 111.55 E-value: 1.07e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSN-GFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAM 80
Cdd:cd03251 1 VEFKNVTFRYPGdGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASlrRQIGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYpHKTVFDNMAFGLKmqrcpkDEIKRRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAI 149
Cdd:cd03251 81 VSQDVFLF-NDTVAENIAYGRP------GATREEVEEAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAIARAL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 150 VRKPEVFLFDEPLSNLDAklrVTMRVKIAQLHRTLKEEgspaTMIYVTHDQTeALTLGDRICVLNHGKI 218
Cdd:cd03251 154 LKDPPILILDEATSALDT---ESERLVQAALERLMKNR----TTFVIAHRLS-TIENADRIVVLEDGKI 214
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
13-240 |
1.13e-28 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 112.18 E-value: 1.13e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 13 YSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDI-----TTGE-------IYIGNTMVNNLpAKErgIAM 80
Cdd:PRK14239 14 YYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLnpevtITGSivynghnIYSPRTDTVDL-RKE--IGM 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHkTVFDNMAFGLKMQRCpKDeiKRRVEDAAEKL--------EITDLLERKPKEMSGGQRQRVAVGRAIVRK 152
Cdd:PRK14239 91 VFQQPNPFPM-SIYENVVYGLRLKGI-KD--KQVLDEAVEKSlkgasiwdEVKDRLHDSALGLSGGQQQRVCIARVLATS 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 153 PEVFLFDEPLSNLDAklrvtmrVKIAQLHRTLKEEGSPATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:PRK14239 167 PKIILLDEPTSALDP-------ISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNPK 239
|
....*...
gi 1468311694 233 NKFVASFI 240
Cdd:PRK14239 240 HKETEDYI 247
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
22-225 |
1.62e-28 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 111.09 E-value: 1.62e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVFQNYALYPhKTVFDNMAF 99
Cdd:cd03249 21 GLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWlrSQIGLVSQEPVLFD-GTIAENIRY 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 100 GLKmqrcpkDEIKRRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAK 168
Cdd:cd03249 100 GKP------DATDEEVEEAAKKANIHDFIMSLPDgydtlvgergsQLSGGQKQRIAIARALLRNPKILLLDEATSALDAE 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 169 lrVTMRVKIAqLHRTLKEEgspaTMIYVTHDQTeALTLGDRICVLNHGKIMQVDTPA 225
Cdd:cd03249 174 --SEKLVQEA-LDRAMKGR----TTIVIAHRLS-TIRNADLIAVLQNGQVVEQGTHD 222
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
4-217 |
1.65e-28 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 115.89 E-value: 1.65e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLP--AKERGIAM 80
Cdd:COG3845 6 LELRGITKRF-GGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIdGKPVRIRSPrdAIALGIGM 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGL---KMQRCPKDEIKRRVEDAAEK--LEItDlLERKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:COG3845 85 VHQHFMLVPNLTVAENIVLGLeptKGGRLDRKAARARIRELSERygLDV-D-PDAKVEDLSVGEQQRVEILKALYRGARI 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 156 FLFDEPLSNLD----AKLRVTMrvkiaqlhRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:COG3845 163 LILDEPTAVLTpqeaDELFEIL--------RRLAAEG--KSIIFITHKLREVMAIADRVTVLRRGK 218
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
20-227 |
2.64e-28 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 114.17 E-value: 2.64e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVFQNYAL---------- 87
Cdd:PRK09536 19 LDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAasRRVASVPQDTSLsfefdvrqvv 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 ----YPHKTVFDNMafglkmqrcpkDEIKRR-VEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:PRK09536 99 emgrTPHRSRFDTW-----------TETDRAaVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPT 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 163 SNLDaklrVTMRVKIAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:PRK09536 168 ASLD----INHQVRTLELVRRLVDDGK--TAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADV 226
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
13-219 |
3.93e-28 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 110.98 E-value: 3.93e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 13 YSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-RG-IAMVFQNyalyPH 90
Cdd:PRK13647 14 YKDGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWvRSkVGLVFQD----PD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 91 -----KTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNL 165
Cdd:PRK13647 90 dqvfsSTVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYL 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 166 DAKLRVTMRVKIAQLHRTLKeegspaTMIYVTHDQTEALTLGDRICVLNHGKIM 219
Cdd:PRK13647 170 DPRGQETLMEILDRLHNQGK------TVIVATHDVDLAAEWADQVIVLKEGRVL 217
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
2-224 |
4.46e-28 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 109.62 E-value: 4.46e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 2 ANVSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIA 79
Cdd:cd03254 1 GEIEFENVNFSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSlrSMIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNYALYPhKTVFDNMAFGlkmQRCPKDEikrRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRA 148
Cdd:cd03254 81 VVLQDTFLFS-GTIMENIRLG---RPNATDE---EVIEAAKEAGAHDFIMKLPNgydtvlgenggNLSQGERQLLAIARA 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 149 IVRKPEVFLFDEPLSNLDAKlrvtMRVKIAQLHRTLKEEgspATMIYVTHdQTEALTLGDRICVLNHGKIMQVDTP 224
Cdd:cd03254 154 MLRDPKILILDEATSNIDTE----TEKLIQEALEKLMKG---RTSIIIAH-RLSTIKNADKILVLDDGKIIEEGTH 221
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
18-228 |
7.61e-28 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 110.59 E-value: 7.61e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNL-------PAKER-GIAMVFQNYALYp 89
Cdd:PRK13643 20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTskqkeikPVRKKvGVVFQFPESQLF- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 90 HKTVFDNMAFGLKMQRCPKDEIKRRvedAAEKLEITDL----LERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNL 165
Cdd:PRK13643 99 EETVLKDVAFGPQNFGIPKEKAEKI---AAEKLEMVGLadefWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGL 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 166 DAKLRVTMRVKIAQLHRTLKeegspaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIY 228
Cdd:PRK13643 176 DPKARIEMMQLFESIHQSGQ------TVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVF 232
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
1-220 |
1.04e-27 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 109.78 E-value: 1.04e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYSNG-------FKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLP 72
Cdd:PRK10419 1 MTLLNVSGLSHHYAHGglsgkhqHQTVlNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 73 -----AKERGIAMVFQNY--ALYPHKTVFDNMAFGLK-MQRCPKDEIKRRVEDAAEKLEITD-LLERKPKEMSGGQRQRV 143
Cdd:PRK10419 81 raqrkAFRRDIQMVFQDSisAVNPRKTVREIIREPLRhLLSLDKAERLARASEMLRAVDLDDsVLDKRPPQLSGGQLQRV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 144 AVGRAIVRKPEVFLFDEPLSNLDAKLRVTMrvkIAQLHRtLKEEGSPAtMIYVTHDqteaLTLGDRIC----VLNHGKIM 219
Cdd:PRK10419 161 CLARALAVEPKLLILDEAVSNLDLVLQAGV---IRLLKK-LQQQFGTA-CLFITHD----LRLVERFCqrvmVMDNGQIV 231
|
.
gi 1468311694 220 Q 220
Cdd:PRK10419 232 E 232
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
4-232 |
1.93e-27 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 108.01 E-value: 1.93e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER---GIAM 80
Cdd:cd03218 1 LRAENLSKRY-GKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRarlGIGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:cd03218 80 LPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDE 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 161 PLSNLDAKlrvtmRVK-IAQLHRTLKEEGspaTMIYVT-HDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:cd03218 160 PFAGVDPI-----AVQdIQKIIKILKDRG---IGVLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANEL 225
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
4-213 |
2.06e-27 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 113.15 E-value: 2.06e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMV 81
Cdd:TIGR02857 322 LEFSGVSVAYPGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSwrDQIAWV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPhKTVFDNMAFGLKMQrcPKDEIKRRVEDAAEKLEITDL-------LERKPKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:TIGR02857 402 PQHPFLFA-GTIAENIRLARPDA--SDAEIREALERAGLDEFVAALpqgldtpIGEGGAGLSGGQAQRLALARAFLRDAP 478
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 155 VFLFDEPLSNLDAKLRVTMRVKIAQLHRTlkeegspATMIYVTHDqTEALTLGDRICVL 213
Cdd:TIGR02857 479 LLLLDEPTAHLDAETEAEVLEALRALAQG-------RTVLLVTHR-LALAALADRIVVL 529
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
18-231 |
2.57e-27 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 109.34 E-value: 2.57e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN------NLPAKERGIAMVFQnyalYPH- 90
Cdd:PRK13634 21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITagkknkKLKPLRKKVGIVFQ----FPEh 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 91 ----KTVFDNMAFGLKMQRCPKDEIKRRvedAAEKLEIT----DLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:PRK13634 97 qlfeETVEKDICFGPMNFGVSEEDAKQK---AREMIELVglpeELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPT 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 163 SNLDAKLRVTMRVKIAQLHRtlkEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYP 231
Cdd:PRK13634 174 AGLDPKGRKEMMEMFYKLHK---EKG--LTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP 237
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-232 |
4.19e-27 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 107.42 E-value: 4.19e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER---G 77
Cdd:COG1137 1 MMTLEAENLVKSY-GKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRarlG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 I------AMVFQNyaLyphkTVFDN-MAFgLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIV 150
Cdd:COG1137 80 IgylpqeASIFRK--L----TVEDNiLAV-LELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 151 RKPEVFLFDEPLSNLDAklrvtmrvkIA-----QLHRTLKEEGspatmIYV--T-HDQTEALTLGDRICVLNHGKIMQVD 222
Cdd:COG1137 153 TNPKFILLDEPFAGVDP---------IAvadiqKIIRHLKERG-----IGVliTdHNVRETLGICDRAYIISEGKVLAEG 218
|
250
....*....|
gi 1468311694 223 TPANIYNYPK 232
Cdd:COG1137 219 TPEEILNNPL 228
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
5-219 |
7.53e-27 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 106.65 E-value: 7.53e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNtmvnNLPAKERG-----IA 79
Cdd:cd03267 22 SLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG----LVPWKRRKkflrrIG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVF-QNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:cd03267 98 VVFgQKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFL 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 159 DEPLSNLDAKLRVTMRvkiAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIM 219
Cdd:cd03267 178 DEPTIGLDVVAQENIR---NFLKEYNRERG--TTVLLTSHYMKDIEALARRVLVIDKGRLL 233
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
19-232 |
9.37e-27 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 111.31 E-value: 9.37e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTT----LRMIAGLEDITTGEIYIGNTMVNNLPAKE----RG--IAMVFQN--YA 86
Cdd:COG4172 25 AVKGVSFDIAAGETLALVGESGSGKSVTalsiLRLLPDPAAHPSGSILFDGQDLLGLSERElrriRGnrIAMIFQEpmTS 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 87 LYPHKTVFDNMAFGLKM-QRCPKDEIKRRVEDAAEKLEITD---LLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:COG4172 105 LNPLHTIGKQIAEVLRLhRGLSGAAARARALELLERVGIPDperRLDAYPHQLSGGQRQRVMIAMALANEPDLLIADEPT 184
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 163 SNLDaklrVTMRVKIAQLHRTLKEEGSPAtMIYVTHDqtealtLG------DRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:COG4172 185 TALD----VTVQAQILDLLKDLQRELGMA-LLLITHD------LGvvrrfaDRVAVMRQGEIVEQGPTAELFAAPQ 249
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
4-231 |
1.31e-26 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 107.19 E-value: 1.31e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFK-AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGL---EDITTGEIYIGNTMVNN---LPAKER 76
Cdd:PRK13640 6 VEFKHVSFTYPDSKKpALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLllpDDNPNSKITVDGITLTAktvWDIREK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 77 gIAMVFQNyalyPHK-----TVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVR 151
Cdd:PRK13640 86 -VGIVFQN----PDNqfvgaTVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 152 KPEVFLFDEPLSNLDAKlrvtMRVKIAQLHRTLKEEGSpATMIYVTHDQTEAlTLGDRICVLNHGKIMQVDTPANIYNYP 231
Cdd:PRK13640 161 EPKIIILDESTSMLDPA----GKEQILKLIRKLKKKNN-LTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIFSKV 234
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
20-210 |
5.06e-26 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 104.51 E-value: 5.06e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGE-IYIGNTMvNNLPA------KERGIAMVFQNYALYPHKT 92
Cdd:PRK11629 25 LHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDvIFNGQPM-SKLSSaakaelRNQKLGFIYQFHHLLPDFT 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 93 VFDNMAFGLKMQRCPKDEIKRRvedAAEKLEITDLLER---KPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKL 169
Cdd:PRK11629 104 ALENVAMPLLIGKKKPAEINSR---ALEMLAAVGLEHRanhRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARN 180
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1468311694 170 RVTmrvkIAQLHRTLKEEGSPATMIyVTHDqteaLTLGDRI 210
Cdd:PRK11629 181 ADS----IFQLLGELNRLQGTAFLV-VTHD----LQLAKRM 212
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-227 |
7.67e-26 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 104.40 E-value: 7.67e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKvvksysNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTG----------------EI--Y 62
Cdd:COG1119 6 LRNVTVRR------GGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGndvrlfgerrggedvwELrkR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 63 IG---NTMVNNLPAKERGIAMV----FQNYALYPHktvfdnmafglkmqrcPKDEIKRRVEDAAEKLEITDLLERKPKEM 135
Cdd:COG1119 80 IGlvsPALQLRFPRDETVLDVVlsgfFDSIGLYRE----------------PTDEQRERARELLELLGLAHLADRPFGTL 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 136 SGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGSPaTMIYVTHDQ-------TEALTLGD 208
Cdd:COG1119 144 SQGEQRRVLIARALVKDPELLILDEPTAGLD----LGARELLLALLDKLAAEGAP-TLVLVTHHVeeippgiTHVLLLKD 218
|
250 260
....*....|....*....|
gi 1468311694 209 -RicVLNHGKIMQVDTPANI 227
Cdd:COG1119 219 gR--VVAAGPKEEVLTSENL 236
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
13-240 |
2.48e-25 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 103.20 E-value: 2.48e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 13 YSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEI-------YIGNTMVNNLPAKERG-IAMVFQN 84
Cdd:PRK14246 19 YINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIkvdgkvlYFGKDIFQIDAIKLRKeVGMVFQQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 85 YALYPHKTVFDNMAFGLKMQRCP-KDEIKRRVEDAAEKL----EITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFD 159
Cdd:PRK14246 99 PNPFPHLSIYDNIAYPLKSHGIKeKREIKKIVEECLRKVglwkEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMD 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 160 EPLSNLDaklrVTMRVKIAQLHRTLKEEgspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASF 239
Cdd:PRK14246 179 EPTSMID----IVNSQAIEKLITELKNE---IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEKY 251
|
.
gi 1468311694 240 I 240
Cdd:PRK14246 252 V 252
|
|
| anch_rpt_ABC |
TIGR03771 |
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ... |
25-229 |
2.90e-25 |
|
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 101.85 E-value: 2.90e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 25 LDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTmvnNLPAKERGIAMVFQNYAL---YP---HKTVFDNMA 98
Cdd:TIGR03771 1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGA---SPGKGWRHIGYVPQRHEFawdFPisvAHTVMSGRT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 99 FGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrVTMRVKIA 178
Cdd:TIGR03771 78 GHIGWLRRPCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLD----MPTQELLT 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 179 QLHRTLKEEGSPATMiyVTHDQTEALTLGDRICVLNhGKIMQVDTPANIYN 229
Cdd:TIGR03771 154 ELFIELAGAGTAILM--TTHDLAQAMATCDRVVLLN-GRVIADGTPQQLQD 201
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
5-218 |
3.01e-25 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 100.37 E-value: 3.01e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG--IAMV 81
Cdd:cd03246 2 EVENVSFRYPGAEPPVlRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGdhVGYL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPhKTVFDNMafglkmqrcpkdeikrrvedaaekleitdllerkpkeMSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:cd03246 82 PQDDELFS-GSIAENI-------------------------------------LSGGQRQRLGLARALYGNPRILVLDEP 123
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 162 LSNLDaklrVTMRVKIAQLHRTLKEEGspATMIYVTHdQTEALTLGDRICVLNHGKI 218
Cdd:cd03246 124 NSHLD----VEGERALNQAIAALKAAG--ATRIVIAH-RPETLASADRILVLEDGRV 173
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
19-263 |
4.49e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 102.86 E-value: 4.49e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGN---TMVNNLPAKERGIAMVFQNyalyPHKT--- 92
Cdd:PRK13633 25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGldtSDEENLWDIRNKAGMVFQN----PDNQiva 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 93 --VFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLR 170
Cdd:PRK13633 101 tiVEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGR 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 171 VTMRVKIAQLHrtlKEEGspATMIYVTHDQTEALTlGDRICVLNHGKIMQVDTPANIYnypKNKFVASFIG--SPSMNLI 248
Cdd:PRK13633 181 REVVNTIKELN---KKYG--ITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIF---KEVEMMKKIGldVPQVTEL 251
|
250
....*....|....*
gi 1468311694 249 DAVIRKAGNDIVIEI 263
Cdd:PRK13633 252 AYELKKEGVDIPSDI 266
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
20-224 |
5.37e-25 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 102.01 E-value: 5.37e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVFQNYaLYPHK-TVFDN 96
Cdd:PRK11231 18 LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQlaRRLALLPQHH-LTPEGiTVREL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGlkmqRCP--------KDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDak 168
Cdd:PRK11231 97 VAYG----RSPwlslwgrlSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLD-- 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 169 lrVTMRVKIAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTP 224
Cdd:PRK11231 171 --INHQVELMRLMRELNTQGK--TVVTVLHDLNQASRYCDHLVVLANGHVMAQGTP 222
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
18-231 |
7.22e-25 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 102.04 E-value: 7.22e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITtGEI-------YIGNTMVN---NLPAKERGIAMVFQNYAL 87
Cdd:PRK14258 21 KILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELE-SEVrvegrveFFNQNIYErrvNLNRLRRQVSMVHPKPNL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 YPhKTVFDNMAFGLKMQRC-PKDEIKRRVEDAAEKLEITDLLERK----PKEMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:PRK14258 100 FP-MSVYDNVAYGVKIVGWrPKLEIDDIVESALKDADLWDEIKHKihksALDLSGGQQQRLCIARALAVKPKVLLMDEPC 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 163 SNLD--AKLRVTMRVKIAQLHRTLkeegspaTMIYVTHDQTEALTLGDRICVL--NHGKIMQV---DTPANIYNYP 231
Cdd:PRK14258 179 FGLDpiASMKVESLIQSLRLRSEL-------TMVIVSHNLHQVSRLSDFTAFFkgNENRIGQLvefGLTKKIFNSP 247
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
4-228 |
1.32e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 101.74 E-value: 1.32e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGF----KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNlPAKERGI- 78
Cdd:PRK13649 3 INLQNVSYTYQAGTpfegRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITS-TSKNKDIk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 ------AMVFQnyalYPH-----KTVFDNMAFGLKMQRCPKDEIKRRvedAAEKLEIT----DLLERKPKEMSGGQRQRV 143
Cdd:PRK13649 82 qirkkvGLVFQ----FPEsqlfeETVLKDVAFGPQNFGVSQEEAEAL---AREKLALVgiseSLFEKNPFELSGGQMRRV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 144 AVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVKIAQLHRtlkeegSPATMIYVTHDQTEALTLGDRICVLNHGKIMQVDT 223
Cdd:PRK13649 155 AIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQ------SGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGK 228
|
....*
gi 1468311694 224 PANIY 228
Cdd:PRK13649 229 PKDIF 233
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
15-220 |
1.34e-24 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 100.17 E-value: 1.34e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 15 NGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVFQNYALYpHKT 92
Cdd:PRK10247 18 GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIyrQQVSYCAQTPTLF-GDT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 93 VFDNMAFGLKMQRCPKDEikRRVEDAAEKLEITD-LLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRV 171
Cdd:PRK10247 97 VYDNLIFPWQIRNQQPDP--AIFLDDLERFALPDtILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKH 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1468311694 172 TMRVKIaqlHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQ 220
Cdd:PRK10247 175 NVNEII---HRYVREQN--IAVLWVTHDKDEINHADKVITLQPHAGEMQ 218
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
4-228 |
6.15e-24 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 99.92 E-value: 6.15e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN----NLPAKERGIA 79
Cdd:PRK13636 6 LKVEELNYNYSDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDysrkGLMKLRESVG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQ--NYALYPhKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFL 157
Cdd:PRK13636 86 MVFQdpDNQLFS-ASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLV 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 158 FDEPLSNLDAKlrvtmrvKIAQLHRTLKE--EGSPATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIY 228
Cdd:PRK13636 165 LDEPTAGLDPM-------GVSEIMKLLVEmqKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
18-219 |
7.68e-24 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 100.16 E-value: 7.68e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIyigntMVNNL-PAKER-----GIAMVF-QNYALYPH 90
Cdd:COG4586 36 EAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEV-----RVLGYvPFKRRkefarRIGVVFgQRSQLWWD 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 91 KTVFDNmaFGL--KMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLD-- 166
Cdd:COG4586 111 LPAIDS--FRLlkAIYRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDvv 188
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 167 AKLRVtmRVKIAQLHRtlkEEGspATMIYVTHDQT--EALTlgDRICVLNHGKIM 219
Cdd:COG4586 189 SKEAI--REFLKEYNR---ERG--TTILLTSHDMDdiEALC--DRVIVIDHGRII 234
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
18-232 |
9.63e-24 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 100.04 E-value: 9.63e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLPAKE----RGIAMVFQN-YA-LYPH 90
Cdd:PRK11308 29 KALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYqGQDLLKADPEAQkllrQKIQIVFQNpYGsLNPR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 91 KTVFDNMAFGLKMQ-RCPKDEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDak 168
Cdd:PRK11308 109 KKVGQILEEPLLINtSLSAAERREKALAMMAKVGLrPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALD-- 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 169 lrVTMRVKIAQLHRTLKEEGSPAtMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:PRK11308 187 --VSVQAQVLNLMMDLQQELGLS-YVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNPR 247
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
14-254 |
1.13e-23 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 99.92 E-value: 1.13e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 14 SNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGL-----EDITTGEIYIG------NTMVNNLPAK-------E 75
Cdd:PRK13631 36 ENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLikskyGTIQVGDIYIGdkknnhELITNPYSKKiknfkelR 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 RGIAMVFQ--NYALYpHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIVRK 152
Cdd:PRK13631 116 RRVSMVFQfpEYQLF-KDTIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLdDSYLERSPFGLSGGQKRRVAIAGILAIQ 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 153 PEVFLFDEPLSNLDAKLRVTMrvkiAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:PRK13631 195 PEILIFDEPTAGLDPKGEHEM----MQLILDAKANNK--TVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTDQH 268
|
250 260
....*....|....*....|..
gi 1468311694 233 NKFVASFIGSPSMNLIDAVIRK 254
Cdd:PRK13631 269 IINSTSIQVPRVIQVINDLIKK 290
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
23-231 |
1.23e-23 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 98.68 E-value: 1.23e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNtmvNNLPAKERG--------IAMVFQNYALYPHKTVF 94
Cdd:PRK11831 26 ISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDG---ENIPAMSRSrlytvrkrMSMLFQSGALFTDMNVF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 95 DNMAFGLKMQ-RCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAklrVTM 173
Cdd:PRK11831 103 DNVAYPLREHtQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDP---ITM 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 174 RV---KIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYP 231
Cdd:PRK11831 180 GVlvkLISELNSALG-----VTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANP 235
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
12-225 |
1.59e-23 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 97.88 E-value: 1.59e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 12 SYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLP----AKERgiAMVFQNYA 86
Cdd:COG4559 8 SVRLGGRTLlDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSpwelARRR--AVLPQHSS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 87 L-YPHkTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAI------VRKPEVFLF- 158
Cdd:COG4559 86 LaFPF-TVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLaqlwepVDGGPRWLFl 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 159 DEPLSNLDaklrvtmrvkIA-QLH-----RTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPA 225
Cdd:COG4559 165 DEPTSALD----------LAhQHAvlrlaRQLARRG--GGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPE 225
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
17-229 |
2.15e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 98.31 E-value: 2.15e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 17 FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNN-------LPAKERgIAMVFQnyalYP 89
Cdd:PRK13646 20 HQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHktkdkyiRPVRKR-IGMVFQ----FP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 90 HKTVFDN-----MAFGLKMQRCPKDEIKRRVEDAAEKLEIT-DLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLS 163
Cdd:PRK13646 95 ESQLFEDtvereIIFGPKNFKMNLDEVKNYAHRLLMDLGFSrDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTA 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 164 NLDAKlrvtMRVKIAQLHRTLKEEGSpATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:PRK13646 175 GLDPQ----SKRQVMRLLKSLQTDEN-KTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFK 235
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
3-218 |
3.09e-23 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 95.70 E-value: 3.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 3 NVSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLED--ITTGEIYIGNTmvnNLPAKE--RGI 78
Cdd:cd03213 8 NLTVTVKSSPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTglGVSGEVLINGR---PLDKRSfrKII 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHKTVFDNMAFGLKMQRcpkdeikrrvedaaekleitdllerkpkeMSGGQRQRVAVGRAIVRKPEVFLF 158
Cdd:cd03213 85 GYVPQDDILHPTLTVRETLMFAAKLRG-----------------------------LSGGERKRVSIALELVSNPSLLFL 135
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 159 DEPLSNLDA----KLRVTMRvKIAQLHRTLkeegspatmIYVTHD-QTEALTLGDRICVLNHGKI 218
Cdd:cd03213 136 DEPTSGLDSssalQVMSLLR-RLADTGRTI---------ICSIHQpSSEIFELFDKLLLLSQGRV 190
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
19-235 |
3.91e-23 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 101.09 E-value: 3.91e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-----RGIAMVFQN-YA-LYPHK 91
Cdd:PRK10261 339 AVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKlqalrRDIQFIFQDpYAsLDPRQ 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 92 TVFDNMAFGLKMQRC-PKDEIKRRVedaAEKLEITDLLE----RKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLD 166
Cdd:PRK10261 419 TVGDSIMEPLRVHGLlPGKAAAARV---AWLLERVGLLPehawRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALD 495
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 167 aklrVTMRVKIAQLHRTLKEEGSPAtMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKF 235
Cdd:PRK10261 496 ----VSIRGQIINLLLDLQRDFGIA-YLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPY 559
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
18-232 |
4.46e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 97.59 E-value: 4.46e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIG------NTMVNNLPAKERGIAMVFQnyalYPHK 91
Cdd:PRK13641 21 KGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAgyhitpETGNKNLKKLRKKVSLVFQ----FPEA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 92 TVFDN-----MAFGLKMQRCPKDEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNL 165
Cdd:PRK13641 97 QLFENtvlkdVEFGPKNFGFSEDEAKEKALKWLKKVGLsEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 166 DAKLRVTMrvkiAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:PRK13641 177 DPEGRKEM----MQLFKDYQKAGH--TVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKE 237
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
17-218 |
5.68e-23 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 95.68 E-value: 5.68e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 17 FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVnnlpakergiAMVFQNYALYPHKTVFDN 96
Cdd:cd03220 35 FWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVS----------SLLGLGGGFNPELTGREN 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVK 176
Cdd:cd03220 105 IYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRR 184
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1468311694 177 IaqlhRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03220 185 L----RELLKQGK--TVILVSHDPSSIKRLCDRALVLEKGKI 220
|
|
| NHLM_micro_ABC2 |
TIGR03797 |
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ... |
1-224 |
1.26e-22 |
|
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 99.65 E-value: 1.26e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRkvvksY-SNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEI-YIGNTMVN-NLPAKERG 77
Cdd:TIGR03797 454 VDRVTFR-----YrPDGPLILDDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVfYDGQDLAGlDVQAVRRQ 528
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 IAMVFQNYALYPhKTVFDNMAFGLKMQrcpkdeikrrVEDAAEKLEITDL---LERKPKEM-----------SGGQRQRV 143
Cdd:TIGR03797 529 LGVVLQNGRLMS-GSIFENIAGGAPLT----------LDEAWEAARMAGLaedIRAMPMGMhtvisegggtlSGGQRQRL 597
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 144 AVGRAIVRKPEVFLFDEPLSNLD-----------AKLRVTmRVKIAqlHR--TLKEegspatmiyvthdqtealtlGDRI 210
Cdd:TIGR03797 598 LIARALVRKPRILLFDEATSALDnrtqaivseslERLKVT-RIVIA--HRlsTIRN--------------------ADRI 654
|
250
....*....|....
gi 1468311694 211 CVLNHGKIMQVDTP 224
Cdd:TIGR03797 655 YVLDAGRVVQQGTY 668
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
12-226 |
1.40e-22 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 95.61 E-value: 1.40e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 12 SYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVFQNYAL- 87
Cdd:PRK13548 9 SVRLGGRTLlDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAElaRRRAVLPQHSSLs 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 YPHkTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVR------KPEVFLFDEP 161
Cdd:PRK13548 89 FPF-TVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAQlwepdgPPRWLLLDEP 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1468311694 162 LSNLDaklrvtmrvkIAQLHRTL-------KEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPAN 226
Cdd:PRK13548 168 TSALD----------LAHQHHVLrlarqlaHERG--LAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAE 227
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
1-229 |
2.09e-22 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 94.58 E-value: 2.09e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER---G 77
Cdd:PRK10895 1 MATLTAKNLAKAY-KGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARarrG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 IAMVFQNYALYPHKTVFDNMAFGLKMQR-CPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVF 156
Cdd:PRK10895 80 IGYLPQEASIFRRLSVYDNLMAVLQIRDdLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFI 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 157 LFDEPLSNLDAklrvTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:PRK10895 160 LLDEPFAGVDP----ISVIDIKRIIEHLRDSG--LGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQ 226
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
4-223 |
3.06e-22 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 98.25 E-value: 3.06e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSY-SNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNN--LPAKERGIAM 80
Cdd:TIGR02203 331 VEFRNVTFRYpGRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADytLASLRRQVAL 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYpHKTVFDNMAFGlkmqrCPKDEIKRRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAI 149
Cdd:TIGR02203 411 VSQDVVLF-NDTIANNIAYG-----RTEQADRAEIERALAAAYAQDFVDKLPLgldtpigengvLLSGGQRQRLAIARAL 484
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 150 VRKPEVFLFDEPLSNLDAKlrvTMRVKIAQLHRTLKEEgspaTMIYVTHDQTeALTLGDRICVLNHGKIMQVDT 223
Cdd:TIGR02203 485 LKDAPILILDEATSALDNE---SERLVQAALERLMQGR----TTLVIAHRLS-TIEKADRIVVMDDGRIVERGT 550
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-220 |
4.97e-22 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 94.87 E-value: 4.97e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 2 ANVSLRKVVKSYSNGFkAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLPAKERGIAM 80
Cdd:PRK13537 6 APIDFRNVEKRYGDKL-VVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLcGEPVPSRARHARQRVGV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMA-----FGLKMQRCpkdeiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:PRK13537 85 VPQFDNLDPDFTVRENLLvfgryFGLSAAAA-----RALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 156 FLFDEPLSNLDAKLRVTMRVKIaqlhRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHG-KIMQ 220
Cdd:PRK13537 160 LVLDEPTTGLDPQARHLMWERL----RSLLARGK--TILLTTHFMEEAERLCDRLCVIEEGrKIAE 219
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
22-199 |
7.10e-22 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 96.67 E-value: 7.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIgntmvnnlPAKERgIAMVFQNYALYPHKTVFDNMAFGL 101
Cdd:COG0488 16 DVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI--------PKGLR-IGYLPQEPPLDDDLTVLDTVLDGD 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 102 ---------------KMQRCPKD-----------------EIKRRVEDAAEKLEIT-DLLERKPKEMSGGQRQRVAVGRA 148
Cdd:COG0488 87 aelraleaeleeleaKLAEPDEDlerlaelqeefealggwEAEARAEEILSGLGFPeEDLDRPVSELSGGWRRRVALARA 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 149 IVRKPEVFLFDEPLSNLDAKlrvtmrvKIAQLHRTLKeeGSPATMIYVTHD 199
Cdd:COG0488 167 LLSEPDLLLLDEPTNHLDLE-------SIEWLEEFLK--NYPGTVLVVSHD 208
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
6-235 |
1.11e-21 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 96.31 E-value: 1.11e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYSngfkAVHGIDLDIQDGEFMVFVGPSGCAKSTT----LRMIAglediTTGEIYIGNTMVNNLPAKE-----R 76
Cdd:PRK15134 292 LKRTVDHNV----VVKNISFTLRPGETLGLVGESGSGKSTTglalLRLIN-----SQGEIWFDGQPLHNLNRRQllpvrH 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 77 GIAMVFQ--NYALYPHKTVFDNMAFGLKMQR--CPKDEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIVR 151
Cdd:PRK15134 363 RIQVVFQdpNSSLNPRLNVLQIIEEGLRVHQptLSAAQREQQVIAVMEEVGLdPETRHRYPAEFSGGQRQRIAIARALIL 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 152 KPEVFLFDEPLSNLDAklrvTMRVKIAQLHRTLKEEGSPAtMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYP 231
Cdd:PRK15134 443 KPSLIILDEPTSSLDK----TVQAQILALLKSLQQKHQLA-YLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAP 517
|
....
gi 1468311694 232 KNKF 235
Cdd:PRK15134 518 QQEY 521
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
4-218 |
1.46e-21 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 92.77 E-value: 1.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLedITTGEI------YIGNT------MVNNL 71
Cdd:PRK09984 5 IRVEKLAKTF-NQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGL--ITGDKSagshieLLGRTvqregrLARDI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 72 PAKERGIAMVFQNYALYPHKTVFDNMAFGlKMQRCP---------KDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQR 142
Cdd:PRK09984 82 RKSRANTGYIFQQFNLVNRLSVLENVLIG-ALGSTPfwrtcfswfTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 143 VAVGRAIVRKPEVFLFDEPLSNLDAKlrvTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:PRK09984 161 VAIARALMQQAKVILADEPIASLDPE---SARIVMDTLRDINQNDG--ITVVVTLHQVDYALRYCERIVALRQGHV 231
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
17-229 |
1.65e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 93.15 E-value: 1.65e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 17 FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVnnlPA------------KERGIAMVFQN 84
Cdd:PRK13645 24 FKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAI---PAnlkkikevkrlrKEIGLVFQFPE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 85 YALYpHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLS 163
Cdd:PRK13645 101 YQLF-QETIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTG 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 164 NLDAKLRVTMrvkIAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:PRK13645 180 GLDPKGEEDF---INLFERLNKEYKK--RIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFS 240
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
22-203 |
2.16e-21 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 91.38 E-value: 2.16e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG------IAMVFQNYALYPHKTVFD 95
Cdd:PRK10584 28 GVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAklrakhVGFVFQSFMLIPTLNALE 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 96 NMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklRVTMRv 175
Cdd:PRK10584 108 NVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLD---RQTGD- 183
|
170 180
....*....|....*....|....*...
gi 1468311694 176 KIAQLHRTLKEEGSpATMIYVTHDQTEA 203
Cdd:PRK10584 184 KIADLLFSLNREHG-TTLILVTHDLQLA 210
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
2-227 |
2.72e-21 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 95.20 E-value: 2.72e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 2 ANVSLRKVVKSYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG--I 78
Cdd:COG4618 329 GRLSVENLTVVPPGSKRPIlRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGrhI 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPhKTVFDNMA-FGlkmqrCPKDEikrRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVG 146
Cdd:COG4618 409 GYLPQDVELFD-GTIAENIArFG-----DADPE---KVVAAAKLAGVHEMILRLPDgydtrigeggaRLSGGQRQRIGLA 479
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 147 RAIVRKPEVFLFDEPLSNLD----AKLRVTMrvkiaqlhRTLKEEGspATMIYVTHDQTeALTLGDRICVLNHGKIMQVD 222
Cdd:COG4618 480 RALYGDPRLVVLDEPNSNLDdegeAALAAAI--------RALKARG--ATVVVITHRPS-LLAAVDKLLVLRDGRVQAFG 548
|
....*
gi 1468311694 223 TPANI 227
Cdd:COG4618 549 PRDEV 553
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
6-225 |
3.59e-21 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 95.18 E-value: 3.59e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYSNGFKAV---HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGI---- 78
Cdd:PRK10535 7 LKDIRRSYPSGEEQVevlKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQlrre 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 --AMVFQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVF 156
Cdd:PRK10535 87 hfGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVI 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 157 LFDEPLSNLDAKLRVTMrvkIAQLHRtLKEEGSpaTMIYVTHDQTEAlTLGDRICVLNHGKIMQvDTPA 225
Cdd:PRK10535 167 LADEPTGALDSHSGEEV---MAILHQ-LRDRGH--TVIIVTHDPQVA-AQAERVIEIRDGEIVR-NPPA 227
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
4-219 |
4.29e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 92.46 E-value: 4.29e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG----FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEI-YIGNTMVNNLPAKE--- 75
Cdd:PRK13651 3 IKVKNIVKIFNKKlpteLKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIeWIFKDEKNKKKTKEkek 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 ----------------------RGIAMVFQ--NYALYpHKTVFDNMAFGLKMQRCPKDEIKRRvedAAEKLEITDL---- 127
Cdd:PRK13651 83 vleklviqktrfkkikkikeirRRVGVVFQfaEYQLF-EQTIEKDIIFGPVSMGVSKEEAKKR---AAKYIELVGLdesy 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 128 LERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKlrvtMRVKIAQLHRTLKEEGSpaTMIYVTHDQTEALTLG 207
Cdd:PRK13651 159 LQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQ----GVKEILEIFDNLNKQGK--TIILVTHDLDNVLEWT 232
|
250
....*....|..
gi 1468311694 208 DRICVLNHGKIM 219
Cdd:PRK13651 233 KRTIFFKDGKII 244
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-231 |
5.32e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 91.40 E-value: 5.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN--NLPAKERGI 78
Cdd:PRK13652 1 MHLIETRDLCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITkeNIREVRKFV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNyalyPHKTVFD-----NMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKP 153
Cdd:PRK13652 81 GLVFQN----PDDQIFSptveqDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEP 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 154 EVFLFDEPLSNLDAKLRVTMrvkIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYP 231
Cdd:PRK13652 157 QVLVLDEPTAGLDPQGVKEL---IDFLNDLPETYG--MTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
18-167 |
5.70e-21 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 90.41 E-value: 5.70e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLED---ITTGEIYIgntmvNNLPAK----ERGIAMVFQNYALYPH 90
Cdd:cd03234 21 RILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEgggTTSGQILF-----NGQPRKpdqfQKCVAYVRQDDILLPG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 91 KTVFDNMAFG--LKMQRCPKDEIKR-RVEDAAEK-LEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLD 166
Cdd:cd03234 96 LTVRETLTYTaiLRLPRKSSDAIRKkRVEDVLLRdLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLD 175
|
.
gi 1468311694 167 A 167
Cdd:cd03234 176 S 176
|
|
| NHLM_micro_ABC1 |
TIGR03796 |
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ... |
20-220 |
6.68e-21 |
|
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274788 [Multi-domain] Cd Length: 710 Bit Score: 94.24 E-value: 6.68e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPaKER---GIAMVFQNYALYpHKTVFDN 96
Cdd:TIGR03796 495 IENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQPWSGEILFDGIPREEIP-REVlanSVAMVDQDIFLF-EGTVRDN 572
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAfgLKMQRCPKDEIKRRVEDAAekleITDLLERKP-----------KEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNL 165
Cdd:TIGR03796 573 LT--LWDPTIPDADLVRACKDAA----IHDVITSRPggydaelaeggANLSGGQRQRLEIARALVRNPSILILDEATSAL 646
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 166 DAklrVTMRvkiaQLHRTLKEEGspATMIYVTHdQTEALTLGDRICVLNHGKIMQ 220
Cdd:TIGR03796 647 DP---ETEK----IIDDNLRRRG--CTCIIVAH-RLSTIRDCDEIIVLERGKVVQ 691
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
18-218 |
7.51e-21 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 88.64 E-value: 7.51e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER---GIAMV---FQNYALYPHK 91
Cdd:cd03215 14 GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAiraGIAYVpedRKREGLVLDL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 92 TVFDNMAfglkmqrcpkdeikrrvedaaekleITDLLerkpkemSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrV 171
Cdd:cd03215 94 SVAENIA-------------------------LSSLL-------SGGNQQKVVLARWLARDPRVLILDEPTRGVD----V 137
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1468311694 172 TMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03215 138 GAKAEIYRLIRELADAG--KAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
6-199 |
8.77e-21 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 93.58 E-value: 8.77e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVFQ 83
Cdd:TIGR02868 337 LRDLSAGYPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEvrRRVSVCAQ 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYpHKTVFDNMAFGLKmqRCPKDEikrrVEDAAEKLEITDLLERKP-----------KEMSGGQRQRVAVGRAIVRK 152
Cdd:TIGR02868 417 DAHLF-DTTVRENLRLARP--DATDEE----LWAALERVGLADWLRALPdgldtvlgeggARLSGGERQRLALARALLAD 489
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1468311694 153 PEVFLFDEPLSNLDAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTHD 199
Cdd:TIGR02868 490 APILLLDEPTEHLDAETA-------DELLEDLLAALSGRTVVLITHH 529
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
20-198 |
1.66e-20 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 92.95 E-value: 1.66e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIyigntmvnNLPAKERgiaMVF---QNY--------AL- 87
Cdd:COG4178 379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRI--------ARPAGAR---VLFlpqRPYlplgtlreALl 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 YPHKTvfdnmafglkmQRCPKDEIK---RRV--EDAAEKLeitDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPL 162
Cdd:COG4178 448 YPATA-----------EAFSDAELRealEAVglGHLAERL---DEEADWDQVLSLGEQQRLAFARLLLHKPDWLFLDEAT 513
|
170 180 190
....*....|....*....|....*....|....*.
gi 1468311694 163 SNLDAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTH 198
Cdd:COG4178 514 SALDEENE-------AALYQLLREELPGTTVISVGH 542
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
19-161 |
1.91e-20 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 88.74 E-value: 1.91e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER---GIAMVFQNYALYPHKTVFD 95
Cdd:TIGR03410 15 ILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERaraGIAYVPQGREIFPRLTVEE 94
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 96 NMAFGlkMQRCPKDEiKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:TIGR03410 95 NLLTG--LAALPRRS-RKIPDEIYELFPVlKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEP 158
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
3-240 |
3.50e-20 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 92.11 E-value: 3.50e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 3 NVSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLpakERGIAMVF 82
Cdd:TIGR01193 473 DIVINDVSYSYGYGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDI---DRHTLRQF 549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QNYAlyPHK------TVFDNMAFGLKmQRCPKDEIKRRVEDAAEKLEITDL-------LERKPKEMSGGQRQRVAVGRAI 149
Cdd:TIGR01193 550 INYL--PQEpyifsgSILENLLLGAK-ENVSQDEIWAACEIAEIKDDIENMplgyqteLSEEGSSISGGQKQRIALARAL 626
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 150 VRKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEgspaTMIYVTHDQTEAlTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:TIGR01193 627 LTDSKVLILDESTSNLD----TITEKKIVNNLLNLQDK----TIIFVAHRLSVA-KQSDKIIVLDHGKIIEQGSHDELLD 697
|
250
....*....|.
gi 1468311694 230 YpkNKFVASFI 240
Cdd:TIGR01193 698 R--NGFYASLI 706
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
35-257 |
3.63e-20 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 89.38 E-value: 3.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 35 FVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN--------NLPAKERGIAMVFQNYALYPhKTVFDNMAFGLKMQR- 105
Cdd:PRK14271 52 LMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGgrsifnyrDVLEFRRRVGMLFQRPNPFP-MSIMDNVLAGVRAHKl 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 106 CPKDEIK----RRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAklrvTMRVKIAQLH 181
Cdd:PRK14271 131 VPRKEFRgvaqARLTEVGLWDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDP----TTTEKIEEFI 206
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 182 RTLKEEgspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIGSPSMNLIDAvirKAGN 257
Cdd:PRK14271 207 RSLADR---LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAETARYVAGLSGDVKDA---KRGN 276
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
5-230 |
3.94e-20 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 88.21 E-value: 3.94e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVV----KSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIgntmvnnlpaKER---- 76
Cdd:COG1134 23 SLKELLlrrrRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEV----------NGRvsal 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 77 -GIAMVFQnyalyPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:COG1134 93 lELGAGFH-----PELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSSGMRARLAFAVATAVDPDI 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 156 FLFDEPLSNLDAKLRVTMRVKIAQlhrtLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNY 230
Cdd:COG1134 168 LLVDEVLAVGDAAFQKKCLARIRE----LRESG--RTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAA 236
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
22-228 |
4.27e-20 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 92.09 E-value: 4.27e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIyigntMVNNLPAKE-------RGIAMVFQNYALYpHKTVF 94
Cdd:TIGR00958 499 GLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQV-----LLDGVPLVQydhhylhRQVALVGQEPVLF-SGSVR 572
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 95 DNMAFGLkmQRCPKDEIKRRVEDAAEKLEITDL-------LERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDA 167
Cdd:TIGR00958 573 ENIAYGL--TDTPDEEIMAAAKAANAHDFIMEFpngydteVGEKGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDA 650
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 168 klrvtmrvKIAQLHRTLKEEGSpATMIYVTHdQTEALTLGDRICVLNHGKIMQVDTPANIY 228
Cdd:TIGR00958 651 --------ECEQLLQESRSRAS-RTVLLIAH-RLSTVERADQILVLKKGSVVEMGTHKQLM 701
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
1-241 |
5.36e-20 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 91.13 E-value: 5.36e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYSnGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMV--NNLPAKERG 77
Cdd:PRK11288 2 SPYLSFDGIGKTFP-GVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIdGQEMRfaSTTAALAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 IAMVFQNYALYPHKTVFDNMAFGlkmqRCP-------KDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIV 150
Cdd:PRK11288 81 VAIIYQELHLVPEMTVAENLYLG----QLPhkggivnRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 151 RKPEVFLFDEPLSNLDAKlrvtmrvKIAQLHRT---LKEEGspATMIYVTHDQTEALTLGDRICVLNHGKimQVDTPANI 227
Cdd:PRK11288 157 RNARVIAFDEPTSSLSAR-------EIEQLFRVireLRAEG--RVILYVSHRMEEIFALCDAITVFKDGR--YVATFDDM 225
|
250
....*....|....
gi 1468311694 228 YNYPKNKFVASFIG 241
Cdd:PRK11288 226 AQVDRDQLVQAMVG 239
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
19-216 |
6.66e-20 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 87.49 E-value: 6.66e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI--GNTMVNNLPAKERGIAMVFQNYALY-------- 88
Cdd:COG4778 26 VLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVrhDGGWVDLAQASPREILALRRRTIGYvsqflrvi 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 89 PHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLL-ERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDA 167
Cdd:COG4778 106 PRVSALDVVAEPLLERGVDREEARARARELLARLNLPERLwDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDA 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1468311694 168 KLRVTMRvkiaQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHG 216
Cdd:COG4778 186 ANRAVVV----ELIEEAKARG--TAIIGIFHDEEVREAVADRVVDVTPF 228
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
4-218 |
7.25e-20 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 87.14 E-value: 7.25e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSN--GFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAK--ERGIA 79
Cdd:cd03248 12 VKFQNVTFAYPTrpDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKylHSKVS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 MVFQNYALYPhKTVFDNMAFGLkmQRCPKDEIKrrveDAAEKLEITDLLERKPKE-----------MSGGQRQRVAVGRA 148
Cdd:cd03248 92 LVGQEPVLFA-RSLQDNIAYGL--QSCSFECVK----EAAQKAHAHSFISELASGydtevgekgsqLSGGQKQRVAIARA 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 149 IVRKPEVFLFDEPLSNLDAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKI 218
Cdd:cd03248 165 LIRNPQVLILDEATSALDAESE-------QQVQQALYDWPERRTVLVIAH-RLSTVERADQILVLDGGRI 226
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
21-227 |
8.57e-20 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 88.12 E-value: 8.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 21 HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVFQNYAL----------- 87
Cdd:PRK10253 24 ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEvaRRIGLLAQNATTpgditvqelva 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 ---YPHKTVFDNMafglkmqrcpKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSN 164
Cdd:PRK10253 104 rgrYPHQPLFTRW----------RKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTW 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 165 LDAKLRVTMRVKIAQLHRtlkEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI 227
Cdd:PRK10253 174 LDISHQIDLLELLSELNR---EKGY--TLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
16-231 |
9.49e-20 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 87.35 E-value: 9.49e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 16 GFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE---RGIAMVFQNYALYPHKT 92
Cdd:PRK11300 17 GLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQiarMGVVRTFQHVRLFREMT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 93 VFDNMAF------------GLKmqrcpKDEIKRRVEDAA--------EKLEITDLLERKPKEMSGGQRQRVAVGRAIVRK 152
Cdd:PRK11300 97 VIENLLVaqhqqlktglfsGLL-----KTPAFRRAESEAldraatwlERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQ 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 153 PEVFLFDEPLSNLDAKLRVTMRVKIAQLHRtlkEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYP 231
Cdd:PRK11300 172 PEILMLDEPAAGLNPKETKELDELIAELRN---EHN--VTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRNNP 245
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
4-219 |
9.58e-20 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 85.44 E-value: 9.58e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSY-SNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLP-AKERGIAMV 81
Cdd:cd03247 1 LSINNVSFSYpEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEkALSSLISVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNyalyPHktVFDnmafglkmqrcpkdeikrrvedaaekleiTDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:cd03247 81 NQR----PY--LFD-----------------------------TTLRNNLGRRFSGGERQRLALARILLQDAPIVLLDEP 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 162 LSNLDAKlrvTMRvkiaQLHRTLKEEGSPATMIYVTHDQTeALTLGDRICVLNHGKIM 219
Cdd:cd03247 126 TVGLDPI---TER----QLLSLIFEVLKDKTLIWITHHLT-GIEHMDKILFLENGKII 175
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-225 |
9.82e-20 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 87.24 E-value: 9.82e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSLRKVVKSYSNgFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE---RG 77
Cdd:PRK11614 3 KVMLSFDKVSAHYGK-IQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKimrEA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 IAMVFQNYALYPHKTVFDNMAFGLKMQRcpKDEIKRRVEDAAEKLeiTDLLERKPKE---MSGGQRQRVAVGRAIVRKPE 154
Cdd:PRK11614 82 VAIVPEGRRVFSRMTVEENLAMGGFFAE--RDQFQERIKWVYELF--PRLHERRIQRagtMSGGEQQMLAIGRALMSQPR 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 155 VFLFDEPLSNLDAKLRVTMRVKIAQlhrtLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPA 225
Cdd:PRK11614 158 LLLLDEPSLGLAPIIIQQIFDTIEQ----LREQG--MTIFLVEQNANQALKLADRGYVLENGHVVLEDTGD 222
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
4-217 |
2.37e-19 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 87.96 E-value: 2.37e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsnGFKA-VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVnnlPAKER----GI 78
Cdd:PRK13536 42 IDLAGVSKSY--GDKAvVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPV---PARARlaraRI 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHKTVFDNMA-----FGLKmqrcpkdeiKRRVEDAAEKLEITDLLERKP----KEMSGGQRQRVAVGRAI 149
Cdd:PRK13536 117 GVVPQFDNLDLEFTVRENLLvfgryFGMS---------TREIEAVIPSLLEFARLESKAdarvSDLSGGMKRRLTLARAL 187
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 150 VRKPEVFLFDEPLSNLDAKLRVTmrvkIAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:PRK13536 188 INDPQLLILDEPTTGLDPHARHL----IWERLRSLLARGK--TILLTTHFMEEAERLCDRLCVLEAGR 249
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
17-242 |
4.19e-19 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 88.76 E-value: 4.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 17 FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMV----------NNLPAKE----RG--IAM 80
Cdd:PRK10261 29 IAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLrrrsrqvielSEQSAAQmrhvRGadMAM 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQN--YALYPHKTVFDNMAFGLKM-QRCPKDEIKRRVEDAAEKLEITD---LLERKPKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:PRK10261 109 IFQEpmTSLNPVFTVGEQIAESIRLhQGASREEAMVEAKRMLDQVRIPEaqtILSRYPHQLSGGMRQRVMIAMALSCRPA 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 155 VFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGSPAtMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNK 234
Cdd:PRK10261 189 VLIADEPTTALD----VTIQAQILQLIKVLQKEMSMG-VIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHP 263
|
....*...
gi 1468311694 235 FVASFIGS 242
Cdd:PRK10261 264 YTRALLAA 271
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
2-199 |
4.41e-19 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 86.09 E-value: 4.41e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 2 ANVSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNlPAKERGIAMV 81
Cdd:PRK15056 5 AGIVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQ-ALQKNLVAYV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYAL---YPhKTVFDNMAFG----LKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:PRK15056 84 PQSEEVdwsFP-VLVEDVVMMGryghMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQ 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1468311694 155 VFLFDEPLSNLDAKlrvtMRVKIAQLHRTLKEEGSpaTMIYVTHD 199
Cdd:PRK15056 163 VILLDEPFTGVDVK----TEARIISLLRELRDEGK--TMLVSTHN 201
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
20-235 |
6.52e-19 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 88.22 E-value: 6.52e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTT----LRMIAGLEDI-TTGEI-YIGNTMVNNLPAKERG-----IAMVFQN--YA 86
Cdd:PRK15134 25 VNDVSLQIEAGETLALVGESGSGKSVTalsiLRLLPSPPVVyPSGDIrFHGESLLHASEQTLRGvrgnkIAMIFQEpmVS 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 87 LYPHKTVFDNMAFGLKMQRCPKDEikrrvedaAEKLEITDLLERK------------PKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:PRK15134 105 LNPLHTLEKQLYEVLSLHRGMRRE--------AARGEILNCLDRVgirqaakrltdyPHQLSGGERQRVMIAMALLTRPE 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 155 VFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGSPAtMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNK 234
Cdd:PRK15134 177 LLIADEPTTALD----VSVQAQILQLLRELQQELNMG-LLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPTHP 251
|
.
gi 1468311694 235 F 235
Cdd:PRK15134 252 Y 252
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-219 |
8.10e-19 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 87.96 E-value: 8.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 2 ANVSLRKVVKSYSNG-FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLP--AKERGI 78
Cdd:PRK11160 337 VSLTLNNVSFTYPDQpQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSeaALRQAI 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHkTVFDNMAFGlkmqrCPK--DEikrRVEDAAEKLEITDLLERKP----------KEMSGGQRQRVAVG 146
Cdd:PRK11160 417 SVVSQRVHLFSA-TLRDNLLLA-----APNasDE---ALIEVLQQVGLEKLLEDDKglnawlgeggRQLSGGEQRRLGIA 487
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 147 RAIVRKPEVFLFDEPLSNLDAKlrvTMRvKIAQLhrtLKEEGSPATMIYVTHDQTeALTLGDRICVLNHGKIM 219
Cdd:PRK11160 488 RALLHDAPLLLLDEPTEGLDAE---TER-QILEL---LAEHAQNKTVLMITHRLT-GLEQFDRICVMDNGQII 552
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
4-229 |
9.36e-19 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 88.53 E-value: 9.36e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYS-NGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMV-NNLPAKERGIAMV 81
Cdd:TIGR01257 929 VCVKNLVKIFEpSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIeTNLDAVRQSLGMC 1008
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:TIGR01257 1009 PQHNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEP 1088
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 162 LSNLDAKLRVTmrvkiaqLHRTLKEEGSPATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:TIGR01257 1089 TSGVDPYSRRS-------IWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKN 1149
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
22-228 |
1.15e-18 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 85.06 E-value: 1.15e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN----NLPAKERGIAMVFQNyalyPHKTVF--- 94
Cdd:PRK13638 19 GLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDyskrGLLALRQQVATVFQD----PEQQIFytd 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 95 --DNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVT 172
Cdd:PRK13638 95 idSDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQ 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 173 MrvkIAQLHRTLKEEGSpatMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIY 228
Cdd:PRK13638 175 M---IAIIRRIVAQGNH---VIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVF 224
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
16-217 |
1.33e-18 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 83.29 E-value: 1.33e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 16 GFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTmvnnlpakergIAMVFQNyALYPHKTVFD 95
Cdd:cd03250 17 TSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS-----------IAYVSQE-PWIQNGTIRE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 96 NMAFGLKMQrcpKDEIKRRVEDAA-----EKLEITDLLE--RKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAK 168
Cdd:cd03250 85 NILFGKPFD---EERYEKVIKACAlepdlEILPDGDLTEigEKGINLSGGQKQRISLARAVYSDADIYLLDDPLSAVDAH 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 169 LrvtmRVKIAQ--LHRTLKEEgspATMIYVTHdQTEALTLGDRICVLNHGK 217
Cdd:cd03250 162 V----GRHIFEncILGLLLNN---KTRILVTH-QLQLLPHADQIVVLDNGR 204
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
23-220 |
1.64e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 86.82 E-value: 1.64e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDittgeiYIGNTMVNNLPAKE-------RGIAMVFQNYALyPHKTVFD 95
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGFLP------YQGSLKINGIELREldpeswrKHLSWVGQNPQL-PHGTLRD 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 96 NMAFGlkmQRCPKDEikrRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAIVRKPEVFLFDEPLSN 164
Cdd:PRK11174 442 NVLLG---NPDASDE---QLQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLLLDEPTAS 515
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 165 LDAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIMQ 220
Cdd:PRK11174 516 LDAHSE-------QLVMQALNAASRRQTTLMVTH-QLEDLAQWDQIWVMQDGQIVQ 563
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
17-227 |
1.77e-18 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 87.10 E-value: 1.77e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 17 FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMV-NNLPAKERGIAMVfQNYALYPHKTVF 94
Cdd:NF033858 279 FTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLfGQPVDaGDIATRRRVGYMS-QAFSLYGELTVR 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 95 DNMA-----FGLkmqrcPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRV--AVgrAIVRKPEVFLFDEPLSNLD- 166
Cdd:NF033858 358 QNLElharlFHL-----PAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLslAV--AVIHKPELLILDEPTSGVDp 430
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 167 ----------AKL----RVTmrvkiaqlhrtlkeegspatmIYV-THDQTEALTLgDRICVLNHGKIMQVDTPANI 227
Cdd:NF033858 431 vardmfwrllIELsredGVT---------------------IFIsTHFMNEAERC-DRISLMHAGRVLASDTPAAL 484
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
19-253 |
2.29e-18 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 84.78 E-value: 2.29e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGL---EDITTGEIYIGNTMVNNLPAKE------RGIAMVFQN--YAL 87
Cdd:PRK09473 31 AVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLlaaNGRIGGSATFNGREILNLPEKElnklraEQISMIFQDpmTSL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 YPHKTVFDNMAFGL----KMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLS 163
Cdd:PRK09473 111 NPYMRVGEQLMEVLmlhkGMSKAEAFEESVRMLDAVKMPEARKRMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTT 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 164 NLDaklrVTMRVKIAQLHRTLKEEGSPAtMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFvasfigsp 243
Cdd:PRK09473 191 ALD----VTVQAQIMTLLNELKREFNTA-IIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPSHPY-------- 257
|
250
....*....|
gi 1468311694 244 SMNLIDAVIR 253
Cdd:PRK09473 258 SIGLLNAVPR 267
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
10-218 |
2.31e-18 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 86.23 E-value: 2.31e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 10 VKSYSNGfKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNL-P--AKERGIAMVFQN-- 84
Cdd:COG1129 259 VEGLSVG-GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRsPrdAIRAGIAYVPEDrk 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 85 -YALYPHKTVFDNMAFGL--KMQRCP---KDEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFL 157
Cdd:COG1129 338 gEGLVLDLSIRENITLASldRLSRGGlldRRRERALAEEYIKRLRIkTPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLI 417
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 158 FDEPLSNLD--AKlrvtmrVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:COG1129 418 LDEPTRGIDvgAK------AEIYRLIRELAAEG--KAVIVISSELPELLGLSDRILVMREGRI 472
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
4-220 |
2.98e-18 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 86.17 E-value: 2.98e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN--NLPAKERGIAMV 81
Cdd:PRK13657 335 VEFDDVSFSYDNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRtvTRASLRRNIAVV 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYpHKTVFDNMAFGlkmqrCPkDEIKRRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAIV 150
Cdd:PRK13657 415 FQDAGLF-NRSIEDNIRVG-----RP-DATDEEMRAAAERAQAHDFIERKPDgydtvvgergrQLSGGERQRLAIARALL 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 151 RKPEVFLFDEPLSNLDAKLRVtmRVKIAqlhrtLKEegspatmiyVTHDQT------------EAltlgDRICVLNHGKI 218
Cdd:PRK13657 488 KDPPILILDEATSALDVETEA--KVKAA-----LDE---------LMKGRTtfiiahrlstvrNA----DRILVFDNGRV 547
|
..
gi 1468311694 219 MQ 220
Cdd:PRK13657 548 VE 549
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
3-224 |
4.14e-18 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 82.16 E-value: 4.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 3 NVSLRKVVKSYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTT----LRMIagleDITTGEIYIGNTMVNNLPAKE-- 75
Cdd:cd03244 2 DIEFKNVSLRYRPNLPPVlKNISFSIKPGEKVGIVGRTGSGKSSLllalFRLV----ELSSGSILIDGVDISKIGLHDlr 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 RGIAMVFQNYALYPhKTVFDNMA-FGlkmqRCPKDEIKRRVEDAAEKLEITDLLERKPKEM-------SGGQRQRVAVGR 147
Cdd:cd03244 78 SRISIIPQDPVLFS-GTIRSNLDpFG----EYSDEELWQALERVGLKEFVESLPGGLDTVVeeggenlSVGQRQLLCLAR 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 148 AIVRKPEVFLFDEPLSNLDaklRVTMrvkiAQLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIMQVDTP 224
Cdd:cd03244 153 ALLRKSKILVLDEATASVD---PETD----ALIQKTIREAFKDCTVLTIAH-RLDTIIDSDRILVLDKGRVVEFDSP 221
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-218 |
5.05e-18 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 85.50 E-value: 5.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVnnlpakergIAMVFQ 83
Cdd:COG0488 316 LELEGLSKSY-GDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGETVK---------IGYFDQ 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYA-LYPHKTVFDNMafglkmqrcpkdeikRRVEDAAEKLEITDLLER---------KP-KEMSGGQRQRVAVGRAIVRK 152
Cdd:COG0488 386 HQEeLDPDKTVLDEL---------------RDGAPGGTEQEVRGYLGRflfsgddafKPvGVLSGGEKARLALAKLLLSP 450
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 153 PEVFLFDEPLSNLDaklrVTMRvkiAQLHRTLKE-EGspaTMIYVTHDQtEAL-TLGDRICVLNHGKI 218
Cdd:COG0488 451 PNVLLLDEPTNHLD----IETL---EALEEALDDfPG---TVLLVSHDR-YFLdRVATRILEFEDGGV 507
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
8-213 |
1.07e-17 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 81.64 E-value: 1.07e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 8 KVVKSYS-NGFKaVHGIDLdIQDGEFMVFVGPSGCAKSTTLRMIAGledittgeiyignTMVNNL-----PAKERGIAMV 81
Cdd:cd03236 5 EPVHRYGpNSFK-LHRLPV-PREGQVLGLVGPNGIGKSTALKILAG-------------KLKPNLgkfddPPDWDEILDE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYAL--YPHKTVFDNMAFGLKMQ---RCPK-------------DEiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRV 143
Cdd:cd03236 70 FRGSELqnYFTKLLEGDVKVIVKPQyvdLIPKavkgkvgellkkkDE-RGKLDELVDQLELRHVLDRNIDQLSGGELQRV 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 144 AVGRAIVRKPEVFLFDEPLSNLDAKLRVTMrvkiAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVL 213
Cdd:cd03236 149 AIAAALARDADFYFFDEPSSYLDIKQRLNA----ARLIRELAEDDN--YVLVVEHDLAVLDYLSDYIHCL 212
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
20-218 |
1.35e-17 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 83.94 E-value: 1.35e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERG--IAMVFQNYALYPhKTVFDNM 97
Cdd:TIGR01842 334 LRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGkhIGYLPQDVELFP-GTVAENI 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 98 AfglKMQRCPKDEikrRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLD 166
Cdd:TIGR01842 413 A---RFGENADPE---KIIEAAKLAGVHELILRLPDgydtvigpggaTLSGGQRQRIALARALYGDPKLVVLDEPNSNLD 486
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1468311694 167 AKLRVTMRVKIAQlhrtLKEEGspATMIYVTHdQTEALTLGDRICVLNHGKI 218
Cdd:TIGR01842 487 EEGEQALANAIKA----LKARG--ITVVVITH-RPSLLGCVDKILVLQDGRI 531
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
19-220 |
1.83e-17 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 80.61 E-value: 1.83e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLPAK-ERGIAMVFQNYALYpHKTVFDN 96
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVdGHDLALADPAWlRRQVGVVLQENVLF-NRSIRDN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLK-MQRcpkdeikRRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAIVRKPEVFLFDEPLSN 164
Cdd:cd03252 96 IALADPgMSM-------ERVIEAAKLAGAHDFISELPEgydtivgeqgaGLSGGQRQRIAIARALIHNPRILIFDEATSA 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 165 LDAKlrvTMRVKIAQLHRTLKEEgspaTMIYVTHdQTEALTLGDRICVLNHGKIMQ 220
Cdd:cd03252 169 LDYE---SEHAIMRNMHDICAGR----TVIIIAH-RLSTVKNADRIIVMEKGRIVE 216
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
15-168 |
2.47e-17 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 79.32 E-value: 2.47e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 15 NGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNL-PAKERGIAMVFQNYALYPHKTV 93
Cdd:TIGR01189 11 GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQrDEPHENILYLGHLPGLKPELSA 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 94 FDNMAFglkMQRCPKDEiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAK 168
Cdd:TIGR01189 91 LENLHF---WAAIHGGA-QRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKA 161
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
4-229 |
2.93e-17 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 82.93 E-value: 2.93e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDI--TTGEI-----------YI------- 63
Cdd:TIGR03269 1 IEVKNLTKKF-DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYepTSGRIiyhvalcekcgYVerpskvg 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 64 ------GNTMVN------NLPAKERG-----IAMVFQ-NYALYPHKTVFDNMAFGLKMQRCPKDEIKRRvedAAEKLEIT 125
Cdd:TIGR03269 80 epcpvcGGTLEPeevdfwNLSDKLRRrirkrIAIMLQrTFALYGDDTVLDNVLEALEEIGYEGKEAVGR---AVDLIEMV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 126 DLLERK---PKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKlrvTMRVKIAQLHRTLKEEGspATMIYVTHdQTE 202
Cdd:TIGR03269 157 QLSHRIthiARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQ---TAKLVHNALEEAVKASG--ISMVLTSH-WPE 230
|
250 260
....*....|....*....|....*...
gi 1468311694 203 ALT-LGDRICVLNHGKIMQVDTPANIYN 229
Cdd:TIGR03269 231 VIEdLSDKAIWLENGEIKEEGTPDEVVA 258
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
4-218 |
5.92e-17 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 82.02 E-value: 5.92e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSnGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNL-PAK--ERGIAM 80
Cdd:PRK15439 12 LCARSISKQYS-GVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLtPAKahQLGIYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGLkmQRCPKDeiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:PRK15439 91 VPQEPLLFPNLSVKENILFGL--PKRQAS--MQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILILDE 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 161 PLSNLDAKLRVTMRVKIaqlhRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:PRK15439 167 PTASLTPAETERLFSRI----RELLAQG--VGIVFISHKLPEIRQLADRISVMRDGTI 218
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
4-216 |
9.18e-17 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 81.37 E-value: 9.18e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSnGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAK---ERGIAM 80
Cdd:PRK09700 6 ISMAGIGKSFG-PVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKlaaQLGIGI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGL----KMQRCPKDEIKRRVEDAAEKLEITDL---LERKPKEMSGGQRQRVAVGRAIVRKP 153
Cdd:PRK09700 85 IYQELSVIDELTVLENLYIGRhltkKVCGVNIIDWREMRVRAAMMLLRVGLkvdLDEKVANLSISHKQMLEIAKTLMLDA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 154 EVFLFDEPLSNLDAKlrvtmrvKIAQLH---RTLKEEGspATMIYVTHDQTEALTLGDRICVLNHG 216
Cdd:PRK09700 165 KVIIMDEPTSSLTNK-------EVDYLFlimNQLRKEG--TAIVYISHKLAEIRRICDRYTVMKDG 221
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
4-166 |
9.40e-17 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 81.79 E-value: 9.40e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMV 81
Cdd:COG5265 358 VRFENVSFGYDPERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASlrAAIGIV 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYpHKTVFDNMAFGlkmqR--CPKDEikrrVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRA 148
Cdd:COG5265 438 PQDTVLF-NDTIAYNIAYG----RpdASEEE----VEAAARAAQIHDFIESLPDgydtrvgerglKLSGGEKQRVAIART 508
|
170
....*....|....*...
gi 1468311694 149 IVRKPEVFLFDEPLSNLD 166
Cdd:COG5265 509 LLKNPPILIFDEATSALD 526
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
27-217 |
1.58e-16 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 78.44 E-value: 1.58e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 27 IQDGEFMVFVGPSGCAKSTTLRMIAGLEDiTTGEIYIGNTMVNNLPAKE----RG---------IAM-VFQNYALYPHkt 92
Cdd:PRK03695 19 VRAGEILHLVGPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLEAWSAAElarhRAylsqqqtppFAMpVFQYLTLHQP-- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 93 vfdnmafglkmQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRV-------AVGRAIVRKPEVFLFDEPLSNL 165
Cdd:PRK03695 96 -----------DKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVrlaavvlQVWPDINPAGQLLLLDEPMNSL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1468311694 166 DaklrVTMRVKIAQLHRTLKEEGSPATMiyVTHDQTEALTLGDRICVLNHGK 217
Cdd:PRK03695 165 D----VAQQAALDRLLSELCQQGIAVVM--SSHDLNHTLRHADRVWLLKQGK 210
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
4-217 |
2.30e-16 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 80.25 E-value: 2.30e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITT--GEIYIGNT--MVNNLPAKER-GI 78
Cdd:TIGR02633 2 LEMKGIVKTF-GGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWSGSplKASNIRDTERaGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 79 AMVFQNYALYPHKTVFDNMAFG----LKMQRCPKDEIKRRVEDAAEKLEITDLLERKP-KEMSGGQRQRVAVGRAIVRKP 153
Cdd:TIGR02633 81 VIIHQELTLVPELSVAENIFLGneitLPGGRMAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQLVEIAKALNKQA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 154 EVFLFDEPLSNLDAKlRVTMRVKIAqlhRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:TIGR02633 161 RLLILDEPSSSLTEK-ETEILLDII---RDLKAHG--VACVYISHKLNEVKAVCDTICVIRDGQ 218
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
20-232 |
2.33e-16 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 77.82 E-value: 2.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTlrmIAGLEDI-------TTGEIYIGNTMVnnLPAKERG--IAMVFQN--YALY 88
Cdd:PRK10418 19 VHGVSLTLQRGRVLALVGGSGSGKSLT---CAAALGIlpagvrqTAGRVLLDGKPV--APCALRGrkIATIMQNprSAFN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 89 PHKTVFDNMAFGLKMQRCPKDEikRRVEDAAEKLEITD---LLERKPKEMSGGQRQRVAVGRAIV-RKPevFLF-DEPLS 163
Cdd:PRK10418 94 PLHTMHTHARETCLALGKPADD--ATLTAALEAVGLENaarVLKLYPFEMSGGMLQRMMIALALLcEAP--FIIaDEPTT 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 164 NLDAklrvTMRVKIAQLHRTLKEEGSPAtMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPK 232
Cdd:PRK10418 170 DLDV----VAQARILDLLESIVQKRALG-MLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPK 233
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
17-235 |
2.96e-16 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 78.63 E-value: 2.96e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 17 FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDittgeiYIGNTMVNNL----------PAKER------GIAM 80
Cdd:PRK11022 20 FRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLID------YPGRVMAEKLefngqdlqriSEKERrnlvgaEVAM 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQN--YALYPHKTVFDNMAFGLKM-QRCPKDEIKRRVEDAAEKLEITD---LLERKPKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:PRK11022 94 IFQDpmTSLNPCYTVGFQIMEAIKVhQGGNKKTRRQRAIDLLNQVGIPDpasRLDVYPHQLSGGMSQRVMIAMAIACRPK 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 155 VFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGSPAtMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNK 234
Cdd:PRK11022 174 LLIADEPTTALD----VTIQAQIIELLLELQQKENMA-LVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAPRHP 248
|
.
gi 1468311694 235 F 235
Cdd:PRK11022 249 Y 249
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
14-221 |
3.42e-16 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 79.83 E-value: 3.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 14 SNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLP--AKERGIAMVFQNY---AL 87
Cdd:PRK09700 273 SRDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLnGKDISPRSPldAVKKGMAYITESRrdnGF 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 YPHKTVFDNMAFG--LKMQRC--------PKDEiKRRVEDAAEKLEIT-DLLERKPKEMSGGQRQRVAVGRAIVRKPEVF 156
Cdd:PRK09700 353 FPNFSIAQNMAISrsLKDGGYkgamglfhEVDE-QRTAENQRELLALKcHSVNQNITELSGGNQQKVLISKWLCCCPEVI 431
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 157 LFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQV 221
Cdd:PRK09700 432 IFDEPTRGID----VGAKAEIYKVMRQLADDGK--VILMVSSELPEIITVCDRIAVFCEGRLTQI 490
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
15-219 |
7.89e-16 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 75.26 E-value: 7.89e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 15 NGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLED--ITTGEIYIGNTMVNNLPAKER---GIAMVFQNYALYP 89
Cdd:cd03217 11 GGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKyeVTEGEILFKGEDITDLPPEERarlGIFLAFQYPPEIP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 90 hktvfdnmafGLKMQrcpkdeikrrvedaaekleitDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAkl 169
Cdd:cd03217 91 ----------GVKNA---------------------DFLRYVNEGFSGGEKKRNEILQLLLLEPDLAILDEPDSGLDI-- 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 170 rVTMRVkIAQLHRTLKEEGSpaTMIYVTHDQTEALTL-GDRICVLNHGKIM 219
Cdd:cd03217 138 -DALRL-VAEVINKLREEGK--SVLIITHYQRLLDYIkPDRVHVLYDGRIV 184
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
22-167 |
9.59e-16 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 75.30 E-value: 9.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIyigntmvnNLPAKERGIAMVF--------QNyALYPHKTV 93
Cdd:PRK13539 20 GLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTI--------KLDGGDIDDPDVAeachylghRN-AMKPALTV 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 94 FDNMAF--GLKMQRCPkdeikrRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDA 167
Cdd:PRK13539 91 AENLEFwaAFLGGEEL------DIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDA 160
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
21-240 |
9.99e-16 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 78.55 E-value: 9.99e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 21 HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLedITTGEIYIGNTMVNNLPAKERGI----AMVFQNYALYPHKTVFDN 96
Cdd:TIGR00955 42 KNVSGVAKPGELLAVMGSSGAGKTTLMNALAFR--SPKGVKGSGSVLLNGMPIDAKEMraisAYVQQDDLFIPTLTVREH 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFG--LKMQR-CPKDEIKRRVEDAAEKLEITDL------LERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDA 167
Cdd:TIGR00955 120 LMFQahLRMPRrVTKKEKRERVDEVLQALGLRKCantrigVPGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLDS 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 168 klrvTMRVKIAQLHRTLKEEGSpaTMIYVTHDQT-EALTLGDRICVLNHGKIMQVDTPANI--------YNYPKNKFVAS 238
Cdd:TIGR00955 200 ----FMAYSVVQVLKGLAQKGK--TIICTIHQPSsELFELFDKIILMAEGRVAYLGSPDQAvpffsdlgHPCPENYNPAD 273
|
..
gi 1468311694 239 FI 240
Cdd:TIGR00955 274 FY 275
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
19-220 |
1.07e-15 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 78.22 E-value: 1.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE-RG-IAMVFQNYALYPhKTVFDN 96
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSwRSrLAVVSQTPFLFS-DTVANN 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGlkmqrCPkDEIKRRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNL 165
Cdd:PRK10789 409 IALG-----RP-DATQQEIEHVARLASVHDDILRLPQgydtevgergvMLSGGQKQRISIARALLLNAEILILDDALSAV 482
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 166 DAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIMQ 220
Cdd:PRK10789 483 DGRTE-------HQILHNLRQWGEGRTVIISAH-RLSALTEASEILVMQHGHIAQ 529
|
|
| type_I_sec_HlyB |
TIGR01846 |
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ... |
23-220 |
1.73e-15 |
|
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273831 [Multi-domain] Cd Length: 694 Bit Score: 77.86 E-value: 1.73e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLPAK-ERGIAMVFQNYALYpHKTVFDNMAFg 100
Cdd:TIGR01846 476 LNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLYTPQHGQVLVdGVDLAIADPAWlRRQMGVVLQENVLF-SRSIRDNIAL- 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 101 lkmqrCPKDEIKRRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKL 169
Cdd:TIGR01846 554 -----CNPGAPFEHVIHAAKLAGAHDFISELPQgyntevgekgaNLSGGQRQRIAIARALVGNPRILIFDEATSALDYES 628
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 170 RvtmrvkiAQLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIMQ 220
Cdd:TIGR01846 629 E-------ALIMRNMREICRGRTVIIIAH-RLSTVRACDRIIVLEKGQIAE 671
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
22-227 |
1.97e-15 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 75.26 E-value: 1.97e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDiTTGEIYIGNTMVNNLPAKE----RG---------IAM-VFQNYAL 87
Cdd:COG4138 14 PISAQVNAGELIHLIGPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDWSAAElarhRAylsqqqsppFAMpVFQYLAL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 YPHKTvfdnmafglkmqrCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVR-KPEV------FLFDE 160
Cdd:COG4138 93 HQPAG-------------ASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvWPTInpegqlLLLDE 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 161 PLSNLDaklrVTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIM------QVDTPANI 227
Cdd:COG4138 160 PMNSLD----VAQQAALDRLLRELCQQG--ITVVMSSHDLNHTLRHADRVWLLKQGKLVasgetaEVMTPENL 226
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
26-212 |
2.66e-15 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 74.75 E-value: 2.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 26 DIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPakergiamvfqNYALYPHKTVFDNMAFGLKMQR 105
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSYKP-----------QYIKADYEGTVRDLLSSITKDF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 106 CPKDEIKrrvEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLK 185
Cdd:cd03237 90 YTHPYFK---TEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLD----VEQRLMASKVIRRFA 162
|
170 180
....*....|....*....|....*..
gi 1468311694 186 EEgSPATMIYVTHDQTEALTLGDRICV 212
Cdd:cd03237 163 EN-NEKTAFVVEHDIIMIDYLADRLIV 188
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
6-217 |
5.60e-15 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 76.12 E-value: 5.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYSnGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITT--GEIYI-GNTMV-NNLPAKER-GIAM 80
Cdd:PRK13549 8 MKNITKTFG-GVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGTyeGEIIFeGEELQaSNIRDTERaGIAI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFGlkmqrcpkDEIKR--RVEDAAEKLEITDLLER---------KPKEMSGGQRQRVAVGRAI 149
Cdd:PRK13549 87 IHQELALVKELSVLENIFLG--------NEITPggIMDYDAMYLRAQKLLAQlkldinpatPVGNLGLGQQQLVEIAKAL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 150 VRKPEVFLFDEPLSNLDAKlrvtmrvKIAQLH---RTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:PRK13549 159 NKQARLLILDEPTASLTES-------ETAVLLdiiRDLKAHG--IACIYISHKLNEVKAISDTICVIRDGR 220
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
18-242 |
7.99e-15 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 73.67 E-value: 7.99e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN--NLPAKERGIAMVFQN--YALYPHKTV 93
Cdd:PRK15112 27 EAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHfgDYSYRSQRIRMIFQDpsTSLNPRQRI 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 94 FDNMAFGLKMQR--CPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrV 171
Cdd:PRK15112 107 SQILDFPLRLNTdlEPEQREKQIIETLRQVGLLPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLD----M 182
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 172 TMRVKIAQLHRTLKEEGSPAtMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYPKNKFVASFIGS 242
Cdd:PRK15112 183 SMRSQLINLMLELQEKQGIS-YIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASPLHELTKRLIAG 252
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
21-224 |
1.13e-14 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 72.79 E-value: 1.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 21 HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLED--ITTGEIYIGNTMVNNLPAKER---GIAMVFQNYALYPHKTVFD 95
Cdd:COG0396 17 KGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKyeVTSGSILLDGEDILELSPDERaraGIFLAFQYPVEIPGVSVSN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 96 NMAFGLKMQRCPK---DEIKRRVEDAAEKLEI-TDLLERKPKE-MSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDA-KL 169
Cdd:COG0396 97 FLRTALNARRGEElsaREFLKLLKEKMKELGLdEDFLDRYVNEgFSGGEKKRNEILQMLLLEPKLAILDETDSGLDIdAL 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 170 RVtmrvkIAQLHRTLKEEGSpaTMIYVTHdQTEALTLG--DRICVLNHGKIMQVDTP 224
Cdd:COG0396 177 RI-----VAEGVNKLRSPDR--GILIITH-YQRILDYIkpDFVHVLVDGRIVKSGGK 225
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
5-218 |
1.15e-14 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 73.04 E-value: 1.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYSNGfKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEI-YIGN----TMVNNLPAKERGIA 79
Cdd:PRK11701 8 SVRGLTKLYGPR-KGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVhYRMRdgqlRDLYALSEAERRRL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 80 M------VFQNYA--LYPHKTVFDN-----MAFGLKMQRcpkdEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAV 145
Cdd:PRK11701 87 LrtewgfVHQHPRdgLRMQVSAGGNigerlMAVGARHYG----DIRATAGDWLERVEIdAARIDDLPTTFSGGMQQRLQI 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 146 GRAIVRKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGSPATMIyVTHDQTEALTLGDRICVLNHGKI 218
Cdd:PRK11701 163 ARNLVTHPRLVFMDEPTGGLD----VSVQARLLDLLRGLVRELGLAVVI-VTHDLAVARLLAHRLLVMKQGRV 230
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
5-199 |
2.64e-14 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 74.20 E-value: 2.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIyigntmvnnLPAKERGIAMVFQN 84
Cdd:TIGR03719 6 TMNRVSKVVPPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEA---------RPQPGIKVGYLPQE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 85 YALYPHKTVFDNMAFGL-----KMQRC---------PKDEIKRRVEDAAE---KLEITDL--LERK-----------PKE 134
Cdd:TIGR03719 77 PQLDPTKTVRENVEEGVaeikdALDRFneisakyaePDADFDKLAAEQAElqeIIDAADAwdLDSQleiamdalrcpPWD 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 135 -----MSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKlrvtmrvKIAQLHRTLKEegSPATMIYVTHD 199
Cdd:TIGR03719 157 advtkLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAE-------SVAWLERHLQE--YPGTVVAVTHD 217
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
14-219 |
3.51e-14 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 73.52 E-value: 3.51e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 14 SNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER---GIAMV---FQNYAL 87
Cdd:COG3845 268 DRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERrrlGVAYIpedRLGRGL 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 YPHKTVFDNMAFGL----KMQRCP---KDEIKRRVEDAAEKLEI-TDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFD 159
Cdd:COG3845 348 VPDMSVAENLILGRyrrpPFSRGGfldRKAIRAFAEELIEEFDVrTPGPDTPARSLSGGNQQKVILARELSRDPKLLIAA 427
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 160 EPLSNLDAKlrvtmrvKIAQLHRTLKE---EGspATMIYVTHDQTEALTLGDRICVLNHGKIM 219
Cdd:COG3845 428 QPTRGLDVG-------AIEFIHQRLLElrdAG--AAVLLISEDLDEILALSDRIAVMYEGRIV 481
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
20-219 |
4.03e-14 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 73.76 E-value: 4.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLediTTGEIYIGNTMVNN-LPAKE--RGIAMVFQNYALYPHKTVFDN 96
Cdd:PLN03211 84 LNGVTGMASPGEILAVLGPSGSGKSTLLNALAGR---IQGNNFTGTILANNrKPTKQilKRTGFVTQDDILYPHLTVRET 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFgLKMQRCPKDEIKRRVEDAAE---------KLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDA 167
Cdd:PLN03211 161 LVF-CSLLRLPKSLTKQEKILVAEsviselgltKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDA 239
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 168 klrvTMRVKIAQLHRTLKEEGSpaTMIYVTHD-QTEALTLGDRICVLNHGKIM 219
Cdd:PLN03211 240 ----TAAYRLVLTLGSLAQKGK--TIVTSMHQpSSRVYQMFDSVLVLSEGRCL 286
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
23-215 |
8.48e-14 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 68.72 E-value: 8.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIgntmvnnlPAKErGIAMVFQN-YalyphktvfdnMAFG- 100
Cdd:cd03223 20 LSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM--------PEGE-DLLFLPQRpY-----------LPLGt 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 101 LKMQRC-PKDeikrrvedaaekleitdllerkpKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRvtmrvkiAQ 179
Cdd:cd03223 80 LREQLIyPWD-----------------------DVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESE-------DR 129
|
170 180 190
....*....|....*....|....*....|....*.
gi 1468311694 180 LHRTLKEEGspATMIYVTHdQTEALTLGDRICVLNH 215
Cdd:cd03223 130 LYQLLKELG--ITVISVGH-RPSLWKFHDRVLDLDG 162
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
4-220 |
8.81e-14 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 72.44 E-value: 8.81e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLP--AKERGIAMV 81
Cdd:PRK10790 341 IDIDNVSFAYRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLShsVLRQGVAMV 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPhKTVFDNMAFGlkmqrcpKDEIKRRVEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAIV 150
Cdd:PRK10790 421 QQDPVVLA-DTFLANVTLG-------RDISEEQVWQALETVQLAELARSLPDglytplgeqgnNLSVGQKQLLALARVLV 492
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 151 RKPEVFLFDEPLSNLDAKLRVTmrvkIAQLHRTLKEEgspATMIYVTHdQTEALTLGDRICVLNHGKIMQ 220
Cdd:PRK10790 493 QTPQILILDEATANIDSGTEQA----IQQALAAVREH---TTLVVIAH-RLSTIVEADTILVLHRGQAVE 554
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
19-166 |
1.11e-13 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 72.36 E-value: 1.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 19 AVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNN--LPAKERGIAMVFQNYALYpHKTVFDN 96
Cdd:PRK11176 358 ALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDytLASLRNQVALVSQNVHLF-NDTIANN 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLKmQRCPKDEIkrrvEDAAEKLEITDLLERKPK-----------EMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNL 165
Cdd:PRK11176 437 IAYART-EQYSREQI----EEAARMAYAMDFINKMDNgldtvigengvLLSGGQRQRIAIARALLRDSPILILDEATSAL 511
|
.
gi 1468311694 166 D 166
Cdd:PRK11176 512 D 512
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
37-170 |
1.14e-13 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 69.13 E-value: 1.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 37 GPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKERGiaMVFQNYALYPHKTVFDNMAFGlkmqrcpkDEIKRRVE 116
Cdd:PRK13541 33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAKPYCT--YIGHNLGLKLEMTVFENLKFW--------SEIYNSAE 102
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 117 D---AAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLR 170
Cdd:PRK13541 103 TlyaAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENR 159
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
109-199 |
1.17e-13 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 72.12 E-value: 1.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 109 DEiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEG 188
Cdd:COG1245 188 DE-RGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLD----IYQRLNVARLIRELAEEG 262
|
90
....*....|.
gi 1468311694 189 SPatMIYVTHD 199
Cdd:COG1245 263 KY--VLVVEHD 271
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
20-221 |
1.84e-13 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 71.90 E-value: 1.84e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTmvnnlpakergIAMVFQNyALYPHKTVFDNMAF 99
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS-----------VAYVPQQ-AWIQNDSLRENILF 721
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 100 GLKMQrcpKDEIKRRVEDAA--EKLEI------TDLLErKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRV 171
Cdd:TIGR00957 722 GKALN---EKYYQQVLEACAllPDLEIlpsgdrTEIGE-KGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGK 797
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1468311694 172 TMRVKIAQLHRTLKEEgspaTMIYVTHDQTeALTLGDRICVLNHGKIMQV 221
Cdd:TIGR00957 798 HIFEHVIGPEGVLKNK----TRILVTHGIS-YLPQVDVIIVMSGGKISEM 842
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
1-217 |
4.41e-13 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 70.14 E-value: 4.41e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 1 MANVSlrkvvKSYSnGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE---RG 77
Cdd:PRK10982 1 MSNIS-----KSFP-GVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEaleNG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 IAMVFQNYALYPHKTVFDNMAFGlkmqRCPK-------DEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIV 150
Cdd:PRK10982 75 ISMVHQELNLVLQRSVMDNMWLG----RYPTkgmfvdqDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFS 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 151 RKPEVFLFDEPLSNLDAKlRVTMRVKIAqlhRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:PRK10982 151 YNAKIVIMDEPTSSLTEK-EVNHLFTII---RKLKERG--CGIVYISHKMEEIFQLCDEITILRDGQ 211
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
23-223 |
7.18e-13 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 70.15 E-value: 7.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLrmiagledittgeiyigNTMVNNLPAKERGIAMVFQNYALYP------HKTVFDN 96
Cdd:PLN03130 636 INLDVPVGSLVAIVGSTGEGKTSLI-----------------SAMLGELPPRSDASVVIRGTVAYVPqvswifNATVRDN 698
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLKMQRcPKDEIKRRVEDAAEKLEI------TDLLERKPKeMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAklR 170
Cdd:PLN03130 699 ILFGSPFDP-ERYERAIDVTALQHDLDLlpggdlTEIGERGVN-ISGGQKQRVSMARAVYSNSDVYIFDDPLSALDA--H 774
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 171 VTMRVkiaqLHRTLKEEGSPATMIYVThDQTEALTLGDRICVLNHGKIMQVDT 223
Cdd:PLN03130 775 VGRQV----FDKCIKDELRGKTRVLVT-NQLHFLSQVDRIILVHEGMIKEEGT 822
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
3-218 |
1.24e-12 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 66.13 E-value: 1.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 3 NVSLRKvvKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGledITTGEIYI-GNTMVNNLPAKE------ 75
Cdd:cd03233 8 NISFTT--GKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALAN---RTEGNVSVeGDIHYNGIPYKEfaekyp 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 RGIAMVFQNYALYPHKTVFDNMAFGLkmqRCPKDEIKRRVedaaekleitdllerkpkemSGGQRQRVAVGRAIVRKPEV 155
Cdd:cd03233 83 GEIIYVSEEDVHFPTLTVRETLDFAL---RCKGNEFVRGI--------------------SGGERKRVSIAEALVSRASV 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 156 FLFDEPLSNLDAKlrVTMRvkIAQLHRTLKEEGSPATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:cd03233 140 LCWDNSTRGLDSS--TALE--ILKCIRTMADVLKTTTFVSLYQASDEIYDLFDKVLVLYEGRQ 198
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
22-167 |
2.10e-12 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 65.59 E-value: 2.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNL-PAKERGIAMVFQNYALYPHKTVFDNMAFg 100
Cdd:cd03231 18 GLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQrDSIARGLLYLGHAPGIKTTLSVLENLRF- 96
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 101 lkmqRCPkDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDA 167
Cdd:cd03231 97 ----WHA-DHSDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDK 158
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
8-199 |
2.29e-12 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 68.30 E-value: 2.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 8 KVVKSYsNGFK-AVHGidLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEI-----------YIGntmvnnlpAKE 75
Cdd:PRK13409 345 DLTKKL-GDFSlEVEG--GEIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVdpelkisykpqYIK--------PDY 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 76 RGIAMVFqnyaLYPHKTVFDNMAFglkmqrcpKDEIkrrvedaAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:PRK13409 414 DGTVEDL----LRSITDDLGSSYY--------KSEI-------IKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADL 474
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1468311694 156 FLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEgSPATMIYVTHD 199
Cdd:PRK13409 475 YLLDEPSAHLD----VEQRLAVAKAIRRIAEE-REATALVVDHD 513
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
20-231 |
3.24e-12 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 65.96 E-value: 3.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAK--ERGIAMVFQNYALYPHKTVFDNM 97
Cdd:PRK10575 27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKafARKVAYLPQQLPAAEGMTVRELV 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 98 AFGlkmqRCP--------KDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKL 169
Cdd:PRK10575 107 AIG----RYPwhgalgrfGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAH 182
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 170 RVTMrvkIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGK---------IMQVDTPANIYNYP 231
Cdd:PRK10575 183 QVDV---LALVHRLSQERG--LTVIAVLHDINMAARYCDYLVALRGGEmiaqgtpaeLMRGETLEQIYGIP 248
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
24-230 |
3.68e-12 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 67.67 E-value: 3.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 24 DLDIQDGEFMVFVGPSGCAKSTTLRMIAG---LEDittGEI-YIGNTMVNNL----PAKERGiamvfqnyalyphkTVFD 95
Cdd:PRK11147 23 ELHIEDNERVCLVGRNGAGKSTLMKILNGevlLDD---GRIiYEQDLIVARLqqdpPRNVEG--------------TVYD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 96 NMAFGLK---------------MQRCPKDEIKRRVEDAAEKLE----------ITDLLER-------KPKEMSGGQRQRV 143
Cdd:PRK11147 86 FVAEGIEeqaeylkryhdishlVETDPSEKNLNELAKLQEQLDhhnlwqlenrINEVLAQlgldpdaALSSLSGGWLRKA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 144 AVGRAIVRKPEVFLFDEPLSNLDAKlrvtmrvKIAQLHRTLKE-EGSpatMIYVTHDQTEALTLGDRICVLNHGKImqVD 222
Cdd:PRK11147 166 ALGRALVSNPDVLLLDEPTNHLDIE-------TIEWLEGFLKTfQGS---IIFISHDRSFIRNMATRIVDLDRGKL--VS 233
|
....*...
gi 1468311694 223 TPANIYNY 230
Cdd:PRK11147 234 YPGNYDQY 241
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
4-199 |
4.33e-12 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 67.50 E-value: 4.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYsNGFK--AVHGidlDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEI-----------YIGNTMvnn 70
Cdd:COG1245 342 VEYPDLTKSY-GGFSleVEGG---EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVdedlkisykpqYISPDY--- 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 71 lpakergiamvfqnyalypHKTVFDNMafglkmqrcpKDEIKRRVEDA------AEKLEITDLLERKPKEMSGGQRQRVA 144
Cdd:COG1245 415 -------------------DGTVEEFL----------RSANTDDFGSSyykteiIKPLGLEKLLDKNVKDLSGGELQRVA 465
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 145 VGRAIVRKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGSPATMIyVTHD 199
Cdd:COG1245 466 IAACLSRDADLYLLDEPSAHLD----VEQRLAVAKAIRRFAENRGKTAMV-VDHD 515
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
4-235 |
4.42e-12 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 67.69 E-value: 4.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNN--LPAKERGIAM 80
Cdd:PLN03232 1235 IKFEDVHLRYRPGLPPVlHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKfgLTDLRRVLSI 1314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 81 VFQNYALYPHKTVFDNMAFglkmqrcpKDEIKRRVEDAAEKLEITDLLERKP-----------KEMSGGQRQRVAVGRAI 149
Cdd:PLN03232 1315 IPQSPVLFSGTVRFNIDPF--------SEHNDADLWEALERAHIKDVIDRNPfgldaevseggENFSVGQRQLLSLARAL 1386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 150 VRKPEVFLFDEPLSNLDAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:PLN03232 1387 LRRSKILVLDEATASVDVRTD-------SLIQRTIREEFKSCTMLVIAH-RLNTIIDCDKILVLSSGQVLEYDSPQELLS 1458
|
....*.
gi 1468311694 230 YPKNKF 235
Cdd:PLN03232 1459 RDTSAF 1464
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
21-184 |
5.58e-12 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 64.44 E-value: 5.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 21 HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAkERGIAMVF---QNyALYPHKTVFDNM 97
Cdd:PRK13538 18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRD-EYHQDLLYlghQP-GIKTELTALENL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 98 AFGLKMQRCPKDeikrrvEDAAEKLEITDLLERK--P-KEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKlrvtmr 174
Cdd:PRK13538 96 RFYQRLHGPGDD------EALWEALAQVGLAGFEdvPvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQ------ 163
|
170
....*....|
gi 1468311694 175 vKIAQLHRTL 184
Cdd:PRK13538 164 -GVARLEALL 172
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
12-216 |
9.33e-12 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 63.89 E-value: 9.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 12 SYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVN-----NLPAKERG-IAMVFQNY 85
Cdd:cd03290 9 SWGSGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESepsfeATRSRNRYsVAYAAQKP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 86 ALYpHKTVFDNMAFG--LKMQRcpkdeiKRRVEDAAEKLEITDLLE--------RKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:cd03290 89 WLL-NATVEENITFGspFNKQR------YKAVTDACSLQPDIDLLPfgdqteigERGINLSGGQRQRICVARALYQNTNI 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1468311694 156 FLFDEPLSNLDAKLR-VTMRVKIAQLHRTLKEegspaTMIYVTHdQTEALTLGDRICVLNHG 216
Cdd:cd03290 162 VFLDDPFSALDIHLSdHLMQEGILKFLQDDKR-----TLVLVTH-KLQYLPHADWIIAMKDG 217
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
4-217 |
9.84e-12 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 62.08 E-value: 9.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG--FKavhGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMvnnlpakergiamv 81
Cdd:cd03221 1 IELENLSKTYGGKllLK---DISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTV-------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 fqNYALYPHktvfdnmafglkmqrcpkdeikrrvedaaekleitdllerkpkeMSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:cd03221 64 --KIGYFEQ--------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEP 97
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 162 LSNLDAKlrvtmrvKIAQLHRTLKEEgsPATMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:cd03221 98 TNHLDLE-------SIEALEEALKEY--PGTVILVSHDRYFLDQVATKIIELEDGK 144
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
109-199 |
1.37e-11 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 65.60 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 109 DEiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEg 188
Cdd:PRK13409 188 DE-RGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD----IRQRLNVARLIRELAEG- 261
|
90
....*....|.
gi 1468311694 189 spATMIYVTHD 199
Cdd:PRK13409 262 --KYVLVVEHD 270
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
18-224 |
1.52e-11 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 63.20 E-value: 1.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE--RGIAMVFQNYALYpHKTVFD 95
Cdd:cd03369 22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDlrSSLTIIPQDPTLF-SGTIRS 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 96 NMAfglkmqrcPKDEIKRrvEDAAEKLEITDllerKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRvtmrv 175
Cdd:cd03369 101 NLD--------PFDEYSD--EEIYGALRVSE----GGLNLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATD----- 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1468311694 176 kiAQLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIMQVDTP 224
Cdd:cd03369 162 --ALIQKTIREEFTNSTILTIAH-RLRTIIDYDKILVMDAGEVKEYDHP 207
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
36-174 |
2.53e-11 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 64.96 E-value: 2.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 36 VGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVnnlpakergIAMVFQNY-ALYPHKTVFDNMAFGLKMQRCPKDEIKRR 114
Cdd:TIGR03719 354 IGPNGAGKSTLFRMITGQEQPDSGTIEIGETVK---------LAYVDQSRdALDPNKTVWEEISGGLDIIKLGKREIPSR 424
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 115 VEDAAEKLEITDlLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKlrvTMR 174
Cdd:TIGR03719 425 AYVGRFNFKGSD-QQKKVGQLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVE---TLR 480
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
7-168 |
2.87e-11 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 65.05 E-value: 2.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 7 RKVVKSYSNgfkavhgIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIG---NTMVNNLPAKERGIAMVFQ 83
Cdd:PTZ00265 395 RKDVEIYKD-------LNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINdshNLKDINLKWWRSKIGVVSQ 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 N-------------YALYPHKTV--------------FDNM------------AFGLKMQRCPKDEI-----------KR 113
Cdd:PTZ00265 468 DpllfsnsiknnikYSLYSLKDLealsnyynedgndsQENKnkrnscrakcagDLNDMSNTTDSNELiemrknyqtikDS 547
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 114 RVEDAAEKLEITDLLERKP-----------KEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAK 168
Cdd:PTZ00265 548 EVVDVSKKVLIHDFVSALPdkyetlvgsnaSKLSGGQKQRISIARAIIRNPKILILDEATSSLDNK 613
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
20-218 |
3.27e-11 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 65.19 E-value: 3.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYigntmvnnlpaKERGIAMVFQNyALYPHKTVFDNMAF 99
Cdd:PTZ00243 676 LRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVW-----------AERSIAYVPQQ-AWIMNATVRGNILF 743
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 100 GlkmqrcpKDEIKRRVEDAAE--KLEiTDL------LERKPKEM----SGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDA 167
Cdd:PTZ00243 744 F-------DEEDAARLADAVRvsQLE-ADLaqlgggLETEIGEKgvnlSGGQKARVSLARAVYANRDVYLLDDPLSALDA 815
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 168 KL--RVTMRVKIAQLHrtlkeegsPATMIYVTHdQTEALTLGDRICVLNHGKI 218
Cdd:PTZ00243 816 HVgeRVVEECFLGALA--------GKTRVLATH-QVHVVPRADYVVALGDGRV 859
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
12-166 |
3.42e-11 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 62.17 E-value: 3.42e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 12 SYSNGFKAVHG-IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIgNTMVNNLPAKERGIAMVFQNYALYPH 90
Cdd:PRK13543 18 AFSRNEEPVFGpLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQI-DGKTATRGDRSRFMAYLGHLPGLKAD 96
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 91 KTVFDNMAFGLKMQRCpkdEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLD 166
Cdd:PRK13543 97 LSTLENLHFLCGLHGR---RAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLD 169
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
4-239 |
4.43e-11 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 62.44 E-value: 4.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGfKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIyigntmvnNLPAKERgIAMVFQ 83
Cdd:PRK09544 5 VSLENVSVSFGQR-RVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI--------KRNGKLR-IGYVPQ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYPHK--TV--FDNMAFGLKmqrcpkdeiKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFD 159
Cdd:PRK09544 75 KLYLDTTLplTVnrFLRLRPGTK---------KEDILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLD 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 160 EPLSNLDAKLRVTMRVKIAQLHRTLKeegspATMIYVTHDQTEALTLGDRICVLNHgKIMQVDTPANIYNYPknKFVASF 239
Cdd:PRK09544 146 EPTQGVDVNGQVALYDLIDQLRRELD-----CAVLMVSHDLHLVMAKTDEVLCLNH-HICCSGTPEVVSLHP--EFISMF 217
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
22-222 |
5.19e-11 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 61.90 E-value: 5.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIgntmvnnlpakergiamVFQNYALYPHKTVFDNMAfgl 101
Cdd:COG2401 48 DLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCV-----------------DVPDNQFGREASLIDAIG--- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 102 kmqrcpkdeikrRVEDAAEKLEITD--------LLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklRVTM 173
Cdd:COG2401 108 ------------RKGDFKDAVELLNavglsdavLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLD---RQTA 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 174 RVKIAQLHRTLKEEGspATMIYVTH--DQTEALTlGDRICVLNHGKIMQVD 222
Cdd:COG2401 173 KRVARNLQKLARRAG--ITLVVATHhyDVIDDLQ-PDLLIFVGYGGVPEEK 220
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
4-218 |
6.79e-11 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 63.45 E-value: 6.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMV--NNLPAKERGIAMV 81
Cdd:PRK10522 323 LELRNVTFAYQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVtaEQPEDYRKLFSAV 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPH-----------KTVFDNMAFgLKMQRcpkdeiKRRVEDAaeklEITDLlerkpkEMSGGQRQRVAVGRAIV 150
Cdd:PRK10522 403 FTDFHLFDQllgpegkpanpALVEKWLER-LKMAH------KLELEDG----RISNL------KLSKGQKKRLALLLALA 465
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 151 RKPEVFLFDEPLSNLDAKLRvtmRVKIAQLHRTLKEEGSpaTMIYVTHDQtEALTLGDRICVLNHGKI 218
Cdd:PRK10522 466 EERDILLLDEWAADQDPHFR---REFYQVLLPLLQEMGK--TIFAISHDD-HYFIHADRLLEMRNGQL 527
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
6-248 |
1.21e-10 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 63.49 E-value: 1.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 6 LRKVVKSYS-NGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNlpakergIAMVFQ 83
Cdd:TIGR01257 1940 LNELTKVYSgTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVaGKSILTN-------ISDVHQ 2012
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 84 NYALYPHKTVFDNMAFG-------LKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVF 156
Cdd:TIGR01257 2013 NMGYCPQFDAIDDLLTGrehlylyARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLV 2092
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 157 LFDEPLSNLDAKLRVTMRVKIAQLHRtlkeEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANI-YNYPKNKF 235
Cdd:TIGR01257 2093 LLDEPTTGMDPQARRMLWNTIVSIIR----EGR--AVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLkSKFGDGYI 2166
|
250
....*....|...
gi 1468311694 236 VASFIGSPSMNLI 248
Cdd:TIGR01257 2167 VTMKIKSPKDDLL 2179
|
|
| OB_MalK |
pfam17912 |
MalK OB fold domain; This entry corresponds to one of two OB-fold domains found in the MalK ... |
241-296 |
1.38e-10 |
|
MalK OB fold domain; This entry corresponds to one of two OB-fold domains found in the MalK transport protein.
Pssm-ID: 465563 [Multi-domain] Cd Length: 53 Bit Score: 56.05 E-value: 1.38e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1468311694 241 GSPSMNLIDAVIRkaGNDIVIEIDfGKQVRIPLEKQMNLLAQINKPVCFGIRPEHI 296
Cdd:pfam17912 1 GSPPMNFLPATVV--EDGLLVLGG-GVTLPLPEGQVLALKLYVGKEVILGIRPEHI 53
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
36-199 |
1.61e-10 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 62.44 E-value: 1.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 36 VGPSGCAKSTTLRMIAGLEDITTGEIYigntmvnnlPAKERGIAMVFQNYALYPHKTVFDN------------------- 96
Cdd:PRK11819 39 LGLNGAGKSTLLRIMAGVDKEFEGEAR---------PAPGIKVGYLPQEPQLDPEKTVRENveegvaevkaaldrfneiy 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGL-----------------KMQRCPKDEIKRRVEDAAEKL-------EITDLlerkpkemSGGQRQRVAVGRAIVRK 152
Cdd:PRK11819 110 AAYAEpdadfdalaaeqgelqeIIDAADAWDLDSQLEIAMDALrcppwdaKVTKL--------SGGERRRVALCRLLLEK 181
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1468311694 153 PEVFLFDEPLSNLDAKlrvtmrvKIAQLHRTLKEegSPATMIYVTHD 199
Cdd:PRK11819 182 PDMLLLDEPTNHLDAE-------SVAWLEQFLHD--YPGTVVAVTHD 219
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
20-218 |
1.81e-10 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 62.33 E-value: 1.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 20 VHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLPAK--ERGIAMVFQNY---ALYPHKTV 93
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLdGHEVVTRSPQDglANGIVYISEDRkrdGLVLGMSV 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 94 FDNMAFglkmqrCPKDEIKR---RVEDAAEKLEITDLLE----RKP------KEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:PRK10762 348 KENMSL------TALRYFSRaggSLKHADEQQAVSDFIRlfniKTPsmeqaiGLLSGGNQQKVAIARGLMTRPKVLILDE 421
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 161 PLSNLDaklrVTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:PRK10762 422 PTRGVD----VGAKKEIYQLINQFKAEG--LSIILVSSEMPEVLGMSDRILVMHEGRI 473
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
15-218 |
2.73e-10 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 60.04 E-value: 2.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 15 NGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLE--DITTGEIYIGNTMVNNLPAKER---GIAMVFQnyalYP 89
Cdd:CHL00131 18 NENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPayKILEGDILFKGESILDLEPEERahlGIFLAFQ----YP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 90 HK-TVFDNMAF-------GLKMQRCPKDEIKRRVEDAAEKLEITDL----LERKPKE-MSGGQRQRVAVGRAIVRKPEVF 156
Cdd:CHL00131 94 IEiPGVSNADFlrlaynsKRKFQGLPELDPLEFLEIINEKLKLVGMdpsfLSRNVNEgFSGGEKKRNEILQMALLDSELA 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 157 LFDEPLSNLDAK-LRVtmrvkIAQLHRTLKeeGSPATMIYVTHDQtealTLGDRIC-----VLNHGKI 218
Cdd:CHL00131 174 ILDETDSGLDIDaLKI-----IAEGINKLM--TSENSIILITHYQ----RLLDYIKpdyvhVMQNGKI 230
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
23-220 |
7.03e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 60.76 E-value: 7.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLR-MIAGLEDITTGEIYIGNTmvnnlpakergIAMVFQNYALYpHKTVFDNMAFGL 101
Cdd:PLN03232 636 INLEIPVGSLVAIVGGTGEGKTSLISaMLGELSHAETSSVVIRGS-----------VAYVPQVSWIF-NATVRENILFGS 703
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 102 KMQrcpKDEIKRRVEDAAEKLEI--------TDLLERKPKeMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAklRVTM 173
Cdd:PLN03232 704 DFE---SERYWRAIDVTALQHDLdllpgrdlTEIGERGVN-ISGGQKQRVSMARAVYSNSDIYIFDDPLSALDA--HVAH 777
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1468311694 174 RVkiaqLHRTLKEEGSPATMIYVThDQTEALTLGDRICVLNHGKIMQ 220
Cdd:PLN03232 778 QV----FDSCMKDELKGKTRVLVT-NQLHFLPLMDRIILVSEGMIKE 819
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
5-217 |
1.35e-09 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 59.63 E-value: 1.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 5 SLRKVVKSYSnGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEI-YIGNTMVNNLP--AKERGIAMV 81
Cdd:PRK10762 6 QLKGIDKAFP-GVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSIlYLGKEVTFNGPksSQEAGIGII 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 82 FQNYALYPHKTVFDNMAFGL----KMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFL 157
Cdd:PRK10762 85 HQELNLIPQLTIAENIFLGRefvnRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVII 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 158 FDEPLSNL-DAKLRVTMRVkIaqlhRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGK 217
Cdd:PRK10762 165 MDEPTDALtDTETESLFRV-I----RELKSQG--RGIVYISHRLKEIFEICDDVTVFRDGQ 218
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
92-215 |
2.03e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 59.27 E-value: 2.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 92 TVFDNMAFGlkMQRCPKDEIKRRVEDAAekleITDLLERKP-----------KEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:PTZ00265 1311 SIYENIKFG--KEDATREDVKRACKFAA----IDEFIESLPnkydtnvgpygKSLSGGQKQRIAIARALLREPKILLLDE 1384
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 161 PLSNLDAKLRVTMRVKIAQLhrtlkEEGSPATMIYVTHdQTEALTLGDRICVLNH 215
Cdd:PTZ00265 1385 ATSSLDSNSEKLIEKTIVDI-----KDKADKTIITIAH-RIASIKRSDKIVVFNN 1433
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
23-216 |
2.29e-09 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 59.15 E-value: 2.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIyigntmvnnlpaKERG-IAMVFQNYALYPhKTVFDNMAFGL 101
Cdd:TIGR01271 445 ISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI------------KHSGrISFSPQTSWIMP-GTIKDNIIFGL 511
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 102 KMqrcpkDEIK-RRVEDAAEKLEITDLLERKPK--------EMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrVT 172
Cdd:TIGR01271 512 SY-----DEYRyTSVIKACQLEEDIALFPEKDKtvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFTHLD----VV 582
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1468311694 173 MRVKIaqLHRTLKEEGSPATMIYVThDQTEALTLGDRICVLNHG 216
Cdd:TIGR01271 583 TEKEI--FESCLCKLMSNKTRILVT-SKLEHLKKADKILLLHEG 623
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
4-219 |
3.08e-09 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 57.82 E-value: 3.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNgFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTlRMIAGLEDITTGE-IYIGNTMVNNLPAKERGIAMvf 82
Cdd:NF000106 14 VEVRGLVKHFGE-VKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRrPWRF*TWCANRRALRRTIG*-- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QNYALYPHKTVF---DNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFD 159
Cdd:NF000106 90 HRPVR*GRRESFsgrENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLD 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 160 EPLSNLDAKLRVTMRVKIaqlhRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKIM 219
Cdd:NF000106 170 EPTTGLDPRTRNEVWDEV----RSMVRDG--ATVLLTTQYMEEAEQLAHELTVIDRGRVI 223
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
17-231 |
7.87e-09 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 56.45 E-value: 7.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 17 FKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLED----ITTGEIYIGNTMVNNLPAKER------GIAMVFQN-- 84
Cdd:COG4170 20 VKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKdnwhVTADRFRWNGIDLLKLSPRERrkiigrEIAMIFQEps 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 85 YALYPHKTVFDNMafglkMQRCPKDEIKR--------RVEDAAE---KLEITD---LLERKPKEMSGGQRQRVAVGRAIV 150
Cdd:COG4170 100 SCLDPSAKIGDQL-----IEAIPSWTFKGkwwqrfkwRKKRAIEllhRVGIKDhkdIMNSYPHELTEGECQKVMIAMAIA 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 151 RKPEVFLFDEPLSNLDAKLRvtmrvkiAQLHRTLKE--EGSPATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIY 228
Cdd:COG4170 175 NQPRLLIADEPTNAMESTTQ-------AQIFRLLARlnQLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQIL 247
|
...
gi 1468311694 229 NYP 231
Cdd:COG4170 248 KSP 250
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
26-213 |
8.09e-09 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 54.50 E-value: 8.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 26 DIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGeiyigntmvnnlpakergiamvfqnyalyphKTVFDNMAFGLKMQR 105
Cdd:cd03222 21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGD-------------------------------NDEWDGITPVYKPQY 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 106 CpkdeikrrvedaaekleitdllerkpkEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLK 185
Cdd:cd03222 70 I---------------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLD----IEQRLNAARAIRRLS 118
|
170 180
....*....|....*....|....*...
gi 1468311694 186 EEGSpATMIYVTHDQTEALTLGDRICVL 213
Cdd:cd03222 119 EEGK-KTALVVEHDLAVLDYLSDRIHVF 145
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
23-182 |
1.15e-08 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 54.57 E-value: 1.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEI-YIGNTMVNNLPAKERGIAMVFQNYALYPHKTVFDNMAFGL 101
Cdd:PRK13540 20 ISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEIlFERQSIKKDLCTYQKQLCFVGHRSGINPYLTLRENCLYDI 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 102 KMQRCPKDeikrrVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVKIaQLH 181
Cdd:PRK13540 100 HFSPGAVG-----ITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKI-QEH 173
|
.
gi 1468311694 182 R 182
Cdd:PRK13540 174 R 174
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
30-168 |
2.15e-08 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 56.27 E-value: 2.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 30 GEFMVFVGPSGCAKSTTLRMIAglEDITTGEIYIGNTMVNNLPAKE---RGIAMVFQNYALYPHKTVFDNMAFGLKMQR- 105
Cdd:TIGR00956 789 GTLTALMGASGAGKTTLLNVLA--ERVTTGVITGGDRLVNGRPLDSsfqRSIGYVQQQDLHLPTSTVRESLRFSAYLRQp 866
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 106 --CPKDEIKRRVEDAAEKLEITDLLER---KPKE-MSGGQRQRVAVGRAIVRKPEVFLF-DEPLSNLDAK 168
Cdd:TIGR00956 867 ksVSKSEKMEYVEEVIKLLEMESYADAvvgVPGEgLNVEQRKRLTIGVELVAKPKLLLFlDEPTSGLDSQ 936
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
36-166 |
2.68e-08 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 55.51 E-value: 2.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 36 VGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVnnlpakergIAMVFQNY-ALYPHKTVFDNMAFGLKMQRCPKDEIKRR 114
Cdd:PRK11819 356 IGPNGAGKSTLFKMITGQEQPDSGTIKIGETVK---------LAYVDQSRdALDPNKTVWEEISGGLDIIKVGNREIPSR 426
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1468311694 115 VEDAAEKLEITDlLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLD 166
Cdd:PRK11819 427 AYVGRFNFKGGD-QQKKVGVLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLD 477
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
22-166 |
6.08e-08 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 54.48 E-value: 6.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQdgefMVFVGPSGCAKSTTLRMIAGLEDITTGEIYigntmvnnLPAKERgIAMVFQNYAlyphktvfDNMAFG- 100
Cdd:PLN03073 531 GIDLDSR----IAMVGPNGIGKSTILKLISGELQPSSGTVF--------RSAKVR-MAVFSQHHV--------DGLDLSs 589
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 101 ---LKMQRCPKDEIKRRVEDAAEKLEITDLLERKPK-EMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLD 166
Cdd:PLN03073 590 nplLYMMRCFPGVPEQKLRAHLGSFGVTGNLALQPMyTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD 659
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
4-227 |
7.82e-08 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 54.36 E-value: 7.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLpakerGIAMVF 82
Cdd:PLN03130 1238 IKFEDVVLRYRPELPPVlHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKF-----GLMDLR 1312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 83 QNYALYPHKTVF--DNMAFGLKmqrcPKDEIKRrvEDAAEKLE---ITDLLERKPKEM-----------SGGQRQRVAVG 146
Cdd:PLN03130 1313 KVLGIIPQAPVLfsGTVRFNLD----PFNEHND--ADLWESLErahLKDVIRRNSLGLdaevseagenfSVGQRQLLSLA 1386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 147 RAIVRKPEVFLFDEPLSNLDAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIMQVDTPAN 226
Cdd:PLN03130 1387 RALLRRSKILVLDEATAAVDVRTD-------ALIQKTIREEFKSCTMLIIAH-RLNTIIDCDRILVLDAGRVVEFDTPEN 1458
|
.
gi 1468311694 227 I 227
Cdd:PLN03130 1459 L 1459
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
24-188 |
2.04e-07 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 52.71 E-value: 2.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 24 DLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAK--ERGIAMVFQ---NYALYPhktvfDNMA 98
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSFEqlQKLVSDEWQrnnTDMLSP-----GEDD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 99 FGLKMQRCPKDEIKR--RVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrVTMRVK 176
Cdd:PRK10938 98 TGRTTAEIIQDEVKDpaRCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLD----VASRQQ 173
|
170
....*....|..
gi 1468311694 177 IAQLHRTLKEEG 188
Cdd:PRK10938 174 LAELLASLHQSG 185
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
27-199 |
2.17e-07 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 52.65 E-value: 2.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 27 IQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMvnnlpakerGIAMvFQNY--ALYPHKTVFDNMAFGlkmq 104
Cdd:PRK11147 342 VQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTKL---------EVAY-FDQHraELDPEKTVMDNLAEG---- 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 105 rcpKDEI-----KRRVedaaekLE-ITDLL-----ERKP-KEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrvt 172
Cdd:PRK11147 408 ---KQEVmvngrPRHV------LGyLQDFLfhpkrAMTPvKALSGGERNRLLLARLFLKPSNLLILDEPTNDLD------ 472
|
170 180
....*....|....*....|....*....
gi 1468311694 173 mrVKIAQLhrtLKE--EGSPATMIYVTHD 199
Cdd:PRK11147 473 --VETLEL---LEEllDSYQGTVLLVSHD 496
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
23-166 |
2.33e-07 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 51.78 E-value: 2.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIyigntmvnnlpaKERG-IAMVFQNYALYPhKTVFDNMAFGL 101
Cdd:cd03291 56 INLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI------------KHSGrISFSSQFSWIMP-GTIKENIIFGV 122
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 102 KMqrcpkDEIKRRVEDAAEKLE--ITDLLERKPKEM-------SGGQRQRVAVGRAIVRKPEVFLFDEPLSNLD 166
Cdd:cd03291 123 SY-----DEYRYKSVVKACQLEedITKFPEKDNTVLgeggitlSGGQRARISLARAVYKDADLYLLDSPFGYLD 191
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
22-166 |
2.80e-07 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 50.95 E-value: 2.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 22 GIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLED--ITTGEIYIGNTMVNNLPAKER---GIAMVFQnyalYPHKTVFDN 96
Cdd:PRK09580 19 GLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDyeVTGGTVEFKGKDLLELSPEDRageGIFMAFQ----YPVEIPGVS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLkmQRCPKDEIKRRVEDAAEKLEITDLLERK------PKEM---------SGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:PRK09580 95 NQFFL--QTALNAVRSYRGQEPLDRFDFQDLMEEKiallkmPEDLltrsvnvgfSGGEKKRNDILQMAVLEPELCILDES 172
|
....*
gi 1468311694 162 LSNLD 166
Cdd:PRK09580 173 DSGLD 177
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
2-161 |
5.27e-07 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 51.66 E-value: 5.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 2 ANVSLR--KVVksysngfkAVHGIDLDIQDGEfMV-FVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNnlpAKERG 77
Cdd:NF033858 5 EGVSHRygKTV--------ALDDVSLDIPAGC-MVgLIGPDGVGKSSLLSLIAGARKIQQGRVEVlGGDMAD---ARHRR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 -----IAMVFQ----NyaLYPHKTVFDNMAF-----GLkmqrcPKDEIKRRVedaAEKLEITDL---LERKPKEMSGGQR 140
Cdd:NF033858 73 avcprIAYMPQglgkN--LYPTLSVFENLDFfgrlfGQ-----DAAERRRRI---DELLRATGLapfADRPAGKLSGGMK 142
|
170 180
....*....|....*....|.
gi 1468311694 141 QRVAVGRAIVRKPEVFLFDEP 161
Cdd:NF033858 143 QKLGLCCALIHDPDLLILDEP 163
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
18-218 |
6.56e-07 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 50.98 E-value: 6.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGL-EDITTGEIYIGNTMV---NNLPAKERGIAMVFQN---YALYPH 90
Cdd:TIGR02633 274 KRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAyPGKFEGNVFINGKPVdirNPAQAIRAGIAMVPEDrkrHGIVPI 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 91 KTVFDNMAFGLKMQRCpkdeIKRRVEDAAEKLEITDLLER-KPK---------EMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:TIGR02633 354 LGVGKNITLSVLKSFC----FKMRIDAAAELQIIGSAIQRlKVKtaspflpigRLSGGNQQKAVLAKMLLTNPRVLILDE 429
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1468311694 161 PLSNLDaklrVTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:TIGR02633 430 PTRGVD----VGAKYEIYKLINQLAQEG--VAIIVVSSELAEVLGLSDRVLVIGEGKL 481
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
30-215 |
7.97e-07 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 48.14 E-value: 7.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 30 GEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTmvnnlpakergiamvfqnyalyphktvfdnmafglkmqrcpkd 109
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDG------------------------------------------- 38
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 110 eikRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLRVTMRVKIAQLHRTLKEEGS 189
Cdd:smart00382 39 ---EDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELRLLLLLKSEK 115
|
170 180
....*....|....*....|....*.
gi 1468311694 190 PATMIYVTHDQTEALTLGDRICVLNH 215
Cdd:smart00382 116 NLTVILTTNDEKDLGPALLRRRFDRR 141
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
23-218 |
1.18e-06 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 50.29 E-value: 1.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYI-GNTMVNNLP--AKERGIAMVFQNY---ALYPHKTVFDN 96
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLdGKPIDIRSPrdAIRAGIMLCPEDRkaeGIIPVHSVADN 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 97 MAFGLKMQRCP-KDEIKRRVEDAAEKLEITDLLERKP------KEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDakl 169
Cdd:PRK11288 352 INISARRHHLRaGCLINNRWEAENADRFIRSLNIKTPsreqliMNLSGGNQQKAILGRWLSEDMKVILLDEPTRGID--- 428
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1468311694 170 rVTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:PRK11288 429 -VGAKHEIYNVIYELAAQG--VAVLFVSSDLPEVLGVADRIVVMREGRI 474
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
18-218 |
2.37e-06 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 49.72 E-value: 2.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIdldIQDGEFMVFVGPSGCAKSTTLRMIAGLED----ITTGEI-YIGNTMVNNLPAKERGIAMVFQNYALYPHKT 92
Cdd:TIGR00956 78 KPMDGL---IKPGELTVVLGRPGSGCSTLLKTIASNTDgfhiGVEGVItYDGITPEEIKKHYRGDVVYNAETDVHFPHLT 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 93 VFDNMAFGLKMqRCP--------KDEIKRRVED---AAEKLEIT-------DLLerkpKEMSGGQRQRVAVGRAIVRKPE 154
Cdd:TIGR00956 155 VGETLDFAARC-KTPqnrpdgvsREEYAKHIADvymATYGLSHTrntkvgnDFV----RGVSGGERKRVSIAEASLGGAK 229
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 155 VFLFDEPLSNLDAKLRVtmrvkiaQLHRTLKE-----EGSPATMIYvtHDQTEALTLGDRICVLNHGKI 218
Cdd:TIGR00956 230 IQCWDNATRGLDSATAL-------EFIRALKTsanilDTTPLVAIY--QCSQDAYELFDKVIVLYEGYQ 289
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
23-218 |
3.40e-06 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 48.96 E-value: 3.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKE---RGIAMVFQN------YALYP--HK 91
Cdd:PRK10982 267 VSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEainHGFALVTEErrstgiYAYLDigFN 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 92 TVFDNM-----AFGLKMQRCPKDEIK-----RRVEDAAEKLEITDLlerkpkemSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:PRK10982 347 SLISNIrnyknKVGLLDNSRMKSDTQwvidsMRVKTPGHRTQIGSL--------SGGNQQKVIIGRWLLTQPEILMLDEP 418
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1468311694 162 LSNLDaklrVTMRVKIAQLHRTLKEEGSPATMIyvTHDQTEALTLGDRICVLNHGKI 218
Cdd:PRK10982 419 TRGID----VGAKFEIYQLIAELAKKDKGIIII--SSEMPELLGITDRILVMSNGLV 469
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
10-229 |
3.97e-06 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 49.14 E-value: 3.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 10 VKSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDiTTGEIYIGNTMVNNLPAKERGIAmvfqnYALYP 89
Cdd:TIGR01271 1225 AKYTEAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSWNSVTLQTWRKA-----FGVIP 1298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 90 HKTVFDNMAFGLKM---QRCPKDEIKRrvedAAEKLEITDLLERKPKEM-----------SGGQRQRVAVGRAIVRKPEV 155
Cdd:TIGR01271 1299 QKVFIFSGTFRKNLdpyEQWSDEEIWK----VAEEVGLKSVIEQFPDKLdfvlvdggyvlSNGHKQLMCLARSILSKAKI 1374
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1468311694 156 FLFDEPLSNLDAklrVTMRVkiaqLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIMQVDTPANIYN 229
Cdd:TIGR01271 1375 LLLDEPSAHLDP---VTLQI----IRKTLKQSFSNCTVILSEH-RVEALLECQQFLVIEGSSVKQYDSIQKLLN 1440
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
18-240 |
4.62e-06 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 47.87 E-value: 4.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 18 KAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLED----ITTGEIYIGNTMVNNLPAKER------GIAMVFQ--NY 85
Cdd:PRK15093 21 KAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKdnwrVTADRMRFDDIDLLRLSPRERrklvghNVSMIFQepQS 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 86 ALYPHKTVFDNMafglkMQRCPKDEIK-----------RRVEDAAEKLEITD---LLERKPKEMSGGQRQRVAVGRAIVR 151
Cdd:PRK15093 101 CLDPSERVGRQL-----MQNIPGWTYKgrwwqrfgwrkRRAIELLHRVGIKDhkdAMRSFPYELTEGECQKVMIAIALAN 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 152 KPEVFLFDEPLSNLDAklrvTMRVKIAQLHRTLKEEGSpATMIYVTHDQTEALTLGDRICVLNHGKIMQVDTPANIYNYP 231
Cdd:PRK15093 176 QPRLLIADEPTNAMEP----TTQAQIFRLLTRLNQNNN-TTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTP 250
|
....*....
gi 1468311694 232 KNKFVASFI 240
Cdd:PRK15093 251 HHPYTQALI 259
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
16-227 |
9.96e-06 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 47.35 E-value: 9.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 16 GFKavhGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAKER-GIAMVF-----QNYALYP 89
Cdd:PRK15439 278 GFR---NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRlARGLVYlpedrQSSGLYL 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 90 HKT--------VFDNMAFGLKmqrcPKDEiKRRVEDAAEKLEIT-DLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDE 160
Cdd:PRK15439 355 DAPlawnvcalTHNRRGFWIK----PARE-NAVLERYRRALNIKfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDE 429
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 161 PLSNLDaklrVTMRVKIAQLHRTLKEEGspATMIYVTHDQTEALTLGDRICVLNHGKI--------MQVDTPANI 227
Cdd:PRK15439 430 PTRGVD----VSARNDIYQLIRSIAAQN--VAVLFISSDLEEIEQMADRVLVMHQGEIsgaltgaaINVDTIMRL 498
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
13-240 |
1.50e-05 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 46.06 E-value: 1.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 13 YSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLPAK--ERGIAMVFQNYALYP 89
Cdd:cd03288 29 YENNLKPVlKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHtlRSRLSIILQDPILFS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 90 hktvfDNMAFGLKMQR-CPKDEIKRRVEDAAEKLEITDL-------LERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEP 161
Cdd:cd03288 109 -----GSIRFNLDPECkCTDDRLWEALEIAQLKNMVKSLpggldavVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 162 LSNLDAKLRVTMR--VKIAQLHRTLkeegspATMIYVTHDQTEAltlgDRICVLNHGKIMQVDTPANIYNYpKNKFVASF 239
Cdd:cd03288 184 TASIDMATENILQkvVMTAFADRTV------VTIAHRVSTILDA----DLVLVLSRGILVECDTPENLLAQ-EDGVFASL 252
|
.
gi 1468311694 240 I 240
Cdd:cd03288 253 V 253
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
108-198 |
2.00e-05 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 46.39 E-value: 2.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 108 KDEIKRRVEDAAEKLEITD--------------------LLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDa 167
Cdd:PLN03073 298 KDAVSQRLEEIYKRLELIDaytaearaasilaglsftpeMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD- 376
|
90 100 110
....*....|....*....|....*....|....*
gi 1468311694 168 klrvtmrvkiaqLHRTLKEEGS----PATMIYVTH 198
Cdd:PLN03073 377 ------------LHAVLWLETYllkwPKTFIVVSH 399
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
58-218 |
2.53e-05 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 46.08 E-value: 2.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 58 TGEIYIGNTMV---NNLPAKERGIAMV---------------FQNYAL-----YPHKTVFDNMAfglkMQRCPKDEIKR- 113
Cdd:PRK13549 317 EGEIFIDGKPVkirNPQQAIAQGIAMVpedrkrdgivpvmgvGKNITLaaldrFTGGSRIDDAA----ELKTILESIQRl 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 114 RVEDAAEKLEITDLlerkpkemSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDaklrVTMRVKIAQLHRTLKEEGspATM 193
Cdd:PRK13549 393 KVKTASPELAIARL--------SGGNQQKAVLAKCLLLNPKILILDEPTRGID----VGAKYEIYKLINQLVQQG--VAI 458
|
170 180
....*....|....*....|....*
gi 1468311694 194 IYVTHDQTEALTLGDRICVLNHGKI 218
Cdd:PRK13549 459 IVISSELPEVLGLSDRVLVMHEGKL 483
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
4-210 |
4.53e-05 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 45.27 E-value: 4.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 4 VSLRKVVKSYSNG--FKavhGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEI-YIGNTMVNNLP---AKErg 77
Cdd:PRK15064 320 LEVENLTKGFDNGplFK---NLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVkWSENANIGYYAqdhAYD-- 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 78 iamvFQNyalypHKTVFDNMAfglkmQ-RCPKDEIKRrVEDAAEKLEIT-DLLERKPKEMSGGQRQRVAVGRAIVRKPEV 155
Cdd:PRK15064 395 ----FEN-----DLTLFDWMS-----QwRQEGDDEQA-VRGTLGRLLFSqDDIKKSVKVLSGGEKGRMLFGKLMMQKPNV 459
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 156 FLFDEPLSNLDaklrvtMRvKIAQLHRTLkeEGSPATMIYVTHDQTEALTLGDRI 210
Cdd:PRK15064 460 LVMDEPTNHMD------ME-SIESLNMAL--EKYEGTLIFVSHDREFVSSLATRI 505
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
17-199 |
6.17e-05 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 43.75 E-value: 6.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 17 FKAVHGIDLDiqdGEFMVFVGPSGCAKSTTlrmIAGLEDITTGEIYIGNTMVNNLP-----AKERG-IAMVFQN-----Y 85
Cdd:cd03240 12 FHERSEIEFF---SPLTLIVGQNGAGKTTI---IEALKYALTGELPPNSKGGAHDPklireGEVRAqVKLAFENangkkY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 86 ALYPHKTVFDNMAFglkmqrCPKDEIKrrvedaaekleitDLLERKPKEMSGGQRQ------RVAVGRAIVRKPEVFLFD 159
Cdd:cd03240 86 TITRSLAILENVIF------CHQGESN-------------WPLLDMRGRCSGGEKVlasliiRLALAETFGSNCGILALD 146
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1468311694 160 EPLSNLDAKLRvtmRVKIAQLHRTLKEEGSPaTMIYVTHD 199
Cdd:cd03240 147 EPTTNLDEENI---EESLAEIIEERKSQKNF-QLIVITHD 182
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
30-174 |
1.78e-04 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 43.68 E-value: 1.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 30 GEFMVFVGPSGCAKSTTLRMIAGLEditTGEIYIGNTMVNNLPAKERGIAMVF----QNYALYPHKTVFDNMAFGLKMqR 105
Cdd:PLN03140 906 GVLTALMGVSGAGKTTLMDVLAGRK---TGGYIEGDIRISGFPKKQETFARISgyceQNDIHSPQVTVRESLIYSAFL-R 981
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1468311694 106 CP----KDEIKRRVEDAAEKLEITDLLER-----KPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAK-LRVTMR 174
Cdd:PLN03140 982 LPkevsKEEKMMFVDEVMELVELDNLKDAivglpGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARaAAIVMR 1060
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
11-220 |
1.83e-04 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 42.88 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 11 KSYSNGFKAVHGIDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIyigntmvnnlpAKERGIAMVFQNYALYPH 90
Cdd:PRK13546 31 KHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKV-----------DRNGEVSVIAISAGLSGQ 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 91 KTVFDNMAFGLKMQRCPKDEIKRRVEDAAEKLEITDLLERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKLR 170
Cdd:PRK13546 100 LTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFA 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1468311694 171 VTMRVKIAQlhrtLKEEGSpaTMIYVTHDQTEALTLGDRICVLNHGKIMQ 220
Cdd:PRK13546 180 QKCLDKIYE----FKEQNK--TIFFVSHNLGQVRQFCTKIAWIEGGKLKD 223
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
13-235 |
8.78e-04 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 41.69 E-value: 8.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 13 YSNGFKAV-HGIDLDIQDGEFMVFVGPSGCAKSTTL----RMIagleDITTGEIyigntMVNNLPAKERGIAMVFQNYAL 87
Cdd:PTZ00243 1318 YREGLPLVlRGVSFRIAPREKVGIVGRTGSGKSTLLltfmRMV----EVCGGEI-----RVNGREIGAYGLRELRRQFSM 1388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 88 YPHKTV-FDNmafglkmqrcpkdEIKRRVE-----DAAE---KLEITDLLERKPKEMSG--------------GQRQRVA 144
Cdd:PTZ00243 1389 IPQDPVlFDG-------------TVRQNVDpfleaSSAEvwaALELVGLRERVASESEGidsrvleggsnysvGQRQLMC 1455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 145 VGRAIVRKPEVF-LFDEPLSNLDAKLRvtmrvkiAQLHRTLKEEGSPATMIYVTHdQTEALTLGDRICVLNHGKIMQVDT 223
Cdd:PTZ00243 1456 MARALLKKGSGFiLMDEATANIDPALD-------RQIQATVMSAFSAYTVITIAH-RLHTVAQYDKIIVMDHGAVAEMGS 1527
|
250
....*....|..
gi 1468311694 224 PANIYNYPKNKF 235
Cdd:PTZ00243 1528 PRELVMNRQSIF 1539
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
23-227 |
1.32e-03 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 41.08 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 23 IDLDIQDGEFMVFVGPSGCAKSTTLRMIAGLEDITTGEIYIGNTMVNNLpakerGIAMVFQNYALYPHKTVFdnMAFGLK 102
Cdd:TIGR00957 1305 INVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKI-----GLHDLRFKITIIPQDPVL--FSGSLR 1377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1468311694 103 MQRCPKDEIKRrvEDAAEKLEITDL----------LERKPKE----MSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAK 168
Cdd:TIGR00957 1378 MNLDPFSQYSD--EEVWWALELAHLktfvsalpdkLDHECAEggenLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1455
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1468311694 169 LRVTMRVKIaqlhRTLKEEgspATMIYVTHDQTealTLGD--RICVLNHGKIMQVDTPANI 227
Cdd:TIGR00957 1456 TDNLIQSTI----RTQFED---CTVLTIAHRLN---TIMDytRVIVLDKGEVAEFGAPSNL 1506
|
|
| TOBE_2 |
pfam08402 |
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the ... |
290-363 |
2.14e-03 |
|
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the C-terminal strand of each domain is supplied by the partner. Probably involved in the recognition of small ligands such as molybdenum and sulphate. Found in ABC transporters immediately after the ATPase domain. In this family a strong RPE motif is found at the presumed N-terminus of the domain.
Pssm-ID: 462465 [Multi-domain] Cd Length: 73 Bit Score: 36.44 E-value: 2.14e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1468311694 290 GIRPEHImfaSVEDKENILHGVLTNIENMGNEKNLYFNIGARELIMRAVA-QDVTLSDIGSIYSLKIDTSFCHLF 363
Cdd:pfam08402 2 AIRPEKI---RLAAAANGLSGTVTDVEYLGDHTRYHVELAGGEELVVRVPnAHARPPAPGDRVGLGWDPEDAHVL 73
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
128-200 |
6.88e-03 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 38.61 E-value: 6.88e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1468311694 128 LERKPKEMSGGQRQRVAVGRAIVRKPEVFLFDEPLSNLDAKlrvtmrvKIAQLHRTLKeeGSPATMIYVTHDQ 200
Cdd:PRK10636 143 LERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDLD-------AVIWLEKWLK--SYQGTLILISHDR 206
|
|
| |
