|
Name |
Accession |
Description |
Interval |
E-value |
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
19-398 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 616.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAP--------GEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSS 90
Cdd:COG0626 2 GPATRAVHAGRDPDPQTGAVSPPIYLTSTFVFPSAealaarfaGEEGGYIYSRYGNPTRRALEEALAALEGGEAALAFAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 91 GVAGIDAIVKS-LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVD 169
Cdd:COG0626 82 GMAAISAVLLAlLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVVD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 170 IEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGP 249
Cdd:COG0626 162 IAAIAAIAHAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNALGAVLSP 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 250 MDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEmDKALAV 329
Cdd:COG0626 242 FDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKGGR-EAARRF 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1475498458 330 LDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:COG0626 321 LDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQALAAL 389
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
21-395 |
0e+00 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 558.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 21 GTRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVK 100
Cdd:pfam01053 1 DTLAVHAGQRPDPQTGAVSVPIYLTSTYVFDFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGMAAITAAIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 101 SL-RPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHA 179
Cdd:pfam01053 81 ALlKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIEAIAKLAKK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 180 HDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGT 259
Cdd:pfam01053 161 HGILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATGAVLSPFDAWLLLRGL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 260 KTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELaDDEMDKALAVLDAAEVFTLA 339
Cdd:pfam01053 241 KTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFEL-KGGLEAAKKFLDNLKLFSLA 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1475498458 340 ESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRAL 395
Cdd:pfam01053 320 VSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQAL 375
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
13-397 |
0e+00 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 540.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 13 EAPKADGFGTRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGE-HKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSG 91
Cdd:PRK07811 6 DHHANQGFATRAIHAGYEPDPATGAVNPPIYASSTFAQDGVGGlRGGYEYARTGNPTRTALEEQLAALEGGAYGRAFSSG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 92 VAGIDAIVKS-LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDI 170
Cdd:PRK07811 86 MAATDCLLRAvLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNPLLSITDI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 171 EALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPM 250
Cdd:PRK07811 166 AALAELAHDAGAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNGAGAVPGPF 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 251 DCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEmDKALAVL 330
Cdd:PRK07811 246 DAYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLAGGE-EAARDFC 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1475498458 331 DAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREkigLTDSLIRLSVGVESFEDLRDDLDRALSR 397
Cdd:PRK07811 325 ARTKVFTLAESLGGVESLIEHPSAMTHASTAGSQLE---VPDDLVRLSVGIEDVADLLADLEQALGQ 388
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
36-396 |
0e+00 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 513.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 36 GAVMTPIYQTSTY--------AQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKSL-RPGD 106
Cdd:cd00614 1 GAVAPPIYQTSTFvfpspaeaADLFALREGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLLALlKAGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 107 HVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAHDITVAV 186
Cdd:cd00614 81 HVVASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHGALLVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 187 DNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGTKTLHLRM 266
Cdd:cd00614 161 DNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 267 EQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEmDKALAVLDAAEVFTLAESLGGVE 346
Cdd:cd00614 241 ERHSENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELKGGL-EAAKKFLNALKLFSLAVSLGGVE 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1475498458 347 SLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALS 396
Cdd:cd00614 320 SLVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
22-396 |
1.13e-168 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 476.52 E-value: 1.13e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKS 101
Cdd:PRK07671 5 TKLIHGGIIGDPSTGAVSVPIYQVSTYKQEAVGKHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAVMML 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 102 LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAHD 181
Cdd:PRK07671 85 FSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIAKEKG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 182 ITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGTKT 261
Cdd:PRK07671 165 LLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRGLKT 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 262 LHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEmdKALAVLDAAEVFTLAES 341
Cdd:PRK07671 245 LGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDVGSEE--TANKVLERLQYFTLAES 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1475498458 342 LGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALS 396
Cdd:PRK07671 323 LGAVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
20-398 |
6.31e-153 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 437.02 E-value: 6.31e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 20 FGTRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIV 99
Cdd:PRK06176 3 MQTKLIHGGISEDTTTGAVSVPIYQTSTYRQDAIGRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHAVF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 100 KSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHA 179
Cdd:PRK06176 83 SLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 180 HDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGT 259
Cdd:PRK06176 163 HGLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQRGI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 260 KTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEmdKALAVLDAAEVFTLA 339
Cdd:PRK06176 243 KTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDS--EAVAFVESLKLFILG 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1475498458 340 ESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK06176 321 ESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKI 379
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
14-398 |
1.49e-149 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 429.83 E-value: 1.49e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 14 APKADGFGTRAVHAGQQPDPSTGAVMTPIYQTSTYA-----QAA---PGEHKGHEYSRVSNPTRTALEGNLASLEGAEHG 85
Cdd:COG2873 2 TEKKYGFETLALHAGQEPDPTTGARAVPIYQTTSYVfddaeHAAdlfALKEPGNIYTRIMNPTTDVLEKRIAALEGGVAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 86 IAFSSGVAGIDAIVKSL-RPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPL 164
Cdd:COG2873 82 LATASGQAAITLAILNLaEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 165 MRLVDIEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVC----------------TN 228
Cdd:COG2873 162 LDVLDIEAIAEIAHEHGVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIVdggnfdwaangkfpelTE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 229 SDE------WAE---------KLRFQ-IKSTGAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYP 292
Cdd:COG2873 242 PDPsyhglvYTEafgnaafitKARVQlLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWVNYP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 293 GLPSHPGHALAQKQMSD-YGGMISFELADDEmDKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLT 371
Cdd:COG2873 322 GLPSHPYHELAQKYLPKgAGGVLTFGLKGGR-EAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAGVT 400
|
410 420
....*....|....*....|....*..
gi 1475498458 372 DSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:COG2873 401 PDLIRLSVGIEDIDDIIADLDQALAAA 427
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
20-398 |
7.79e-136 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 393.75 E-value: 7.79e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 20 FGTRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIV 99
Cdd:PRK08064 7 IDTLLLHNQYKHDKQTGAVNVPIYHASTFHQFDFDTFGKYDYSRSGNPTREALEDIIAELEGGTKGFAFASGMAAISTAF 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 100 KSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHA 179
Cdd:PRK08064 87 LLLSKGDHVLISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGVVKLAKA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 180 HDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGT 259
Cdd:PRK08064 167 IGCLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKDEELAQKLYFLQNSFGAVLGVQDCWLVLRGL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 260 KTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEMDKALavLDAAEVFTLA 339
Cdd:PRK08064 247 KTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTLQSEEAVRQF--VSHVKLPVFA 324
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1475498458 340 ESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK08064 325 VSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYV 383
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
22-395 |
2.42e-135 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 392.27 E-value: 2.42e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPStGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKS 101
Cdd:TIGR01329 3 TLLVNTDNKNDPY-DASSMPIYQTATFKQPLAIENGPYDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAALDVITRL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 102 LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAHD 181
Cdd:TIGR01329 82 LNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRKISEMAHAQN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 182 ITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGTKT 261
Cdd:TIGR01329 162 ALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTGSGLAPFDCWLLLRGIKT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 262 LHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEMDKALavLDAAEVFTLAES 341
Cdd:TIGR01329 242 LAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKGAGSVLSFETGSVALSKRL--VEATKLFSITVS 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1475498458 342 LGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRAL 395
Cdd:TIGR01329 320 FGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAF 373
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
19-398 |
3.70e-134 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 389.96 E-value: 3.70e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPSTGAVMTPIYQTSTYA--------QAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSS 90
Cdd:PRK06234 8 GFATKAIHGGHIGDKQFGSLATPIYQTSTFIfdsaeqggRRFAGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAAS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 91 GVAGI-DAIVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVD 169
Cdd:PRK06234 88 GMGAIsSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVTD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 170 IEALAERAHAH--DITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNsDEWAEKLRFQ-IKS-TGA 245
Cdd:PRK06234 168 IKAISNIAHENnkECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGK-EEFINQVKLFgIKDmTGS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 246 APGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDeMDK 325
Cdd:PRK06234 247 VIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKGG-VEE 325
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1475498458 326 ALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK06234 326 GKVVMNNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQALDLI 398
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
19-396 |
6.01e-131 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 381.84 E-value: 6.01e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPSTGAVMTPIYQTSTYA--------QAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSS 90
Cdd:PRK07503 9 GFSTRAIHHGYDPLDHGGALVPPVYLTATFAfptaeygaECFAGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVALAS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 91 GVAGIDAIVKS-LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVD 169
Cdd:PRK07503 89 GMGAITATLWTlLRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 170 IEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTnSDEWAEKLRFQ-IKS-TGAAP 247
Cdd:PRK07503 169 IAAVAEIAHGAGAKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVG-GKALADRIRLEgLKDmTGAVM 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 248 GPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDeMDKAL 327
Cdd:PRK07503 248 SPFDAFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELKGG-IAAGR 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1475498458 328 AVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALS 396
Cdd:PRK07503 327 RFMNALQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALD 395
|
|
| O_succ_thio_ly |
TIGR02080 |
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, ... |
22-395 |
6.68e-131 |
|
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 131135 Cd Length: 382 Bit Score: 381.07 E-value: 6.68e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKS 101
Cdd:TIGR02080 6 TIAVRSGLNSDTQYGCVVPPIYLSTTYNFTGFNEPRAYDYSRSGNPTRDLLQQALAELEGGAGAVVTNTGMSAIHLVTTA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 102 -LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAH 180
Cdd:TIGR02080 86 lLGPDDLLVAPHDCYGGTYRLLNALAKKGCFRVLFVDQGDEQALRAALAQKPKLVLIETPSNPLLRVVDIAKICHLAKAV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 181 DITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGTK 260
Cdd:TIGR02080 166 GAVVVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVIAGAVIAKDPQVAEELAWWANNLGVTGGAFDSYLTLRGLR 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 261 TLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEmDKALAVLDAAEVFTLAE 340
Cdd:TIGR02080 246 TLVARMRLQQRNAQAIVEYLQTQPLVKKIYYPGLPDHPGHEIAARQQKGFGAMLSFELKGGE-QTVRRFLGGLSLFTLAE 324
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1475498458 341 SLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRAL 395
Cdd:TIGR02080 325 SLGGVESLIAHPATMTHAAMGPEARAEAGISDTLLRLSVGLEDADDLIADLEQGL 379
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
19-395 |
1.37e-129 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 378.08 E-value: 1.37e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPSTGAVMTPIYQTSTYAQAA--------PGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSS 90
Cdd:TIGR01328 3 TFATRAIHAGYPPKDQFGALTPPIYQTSTFVFDSceqggnrfAGQESGYIYSRLGNPTVSNLEGRIAFLEGTEAAVATSS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 91 GVAGIDAIVKS-LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVD 169
Cdd:TIGR01328 83 GMGAIAATLLTiLKAGDHLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKLID 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 170 IEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKS-TGAAPG 248
Cdd:TIGR01328 163 MERVCRDAHSQGVKVIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQIRMVGIKDmTGSVIS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 249 PMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEMDkALA 328
Cdd:TIGR01328 243 PFDAWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMITFELKGGFAG-AKK 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1475498458 329 VLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRAL 395
Cdd:TIGR01328 322 LLNNLKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQAL 388
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
22-398 |
3.87e-129 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 375.96 E-value: 3.87e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKS 101
Cdd:PRK08247 7 TKLAQIGNRSDERTGTVNPPVYFSTAYRHEGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQGFACSSGMAAIQLVMSL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 102 LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAHD 181
Cdd:PRK08247 87 FRSGDELIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQETDIAAIAKIAKKHG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 182 ITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGTKT 261
Cdd:PRK08247 167 LLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQELCERLAYYQNAAGAVLSPFDSWLLIRGMKT 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 262 LHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGlpshpghalaqkqmsdYGGMISFELADDEMDKALavLDAAEVFTLAES 341
Cdd:PRK08247 247 LALRMRQHEENAKAIAAFLNEQPGVTDVLYPG----------------RGGMLSFRLQDEEWVNPF--LKSLKLITFAES 308
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1475498458 342 LGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK08247 309 LGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAFKQV 365
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
20-398 |
1.38e-128 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 375.33 E-value: 1.38e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 20 FGTRAVHAGQQPDPSTGAVMTPIYQTSTYAQAA--------PGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSG 91
Cdd:PRK06767 6 METALIHHGYTSEEHKGSLTPPLFQTSTFTFETaqqgeasfAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEALAFGSG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 92 VAGIDAIVKSL-RPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDI 170
Cdd:PRK06767 86 MAAISATLIGFlKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMKLIDL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 171 EALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPM 250
Cdd:PRK06767 166 KQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDIGGIMAPF 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 251 DCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYpglpshPGHALAQKQMSDYGGMISFELADDEMDkALAVL 330
Cdd:PRK06767 246 DAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWY------PEGELASRQMKRGGGVISFSIKGGKEE-TQAFI 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1475498458 331 DAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK06767 319 NDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALKKI 386
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
19-397 |
1.65e-125 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 367.40 E-value: 1.65e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPStGAVMTPIYQTSTY-----AQAAP---GEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSS 90
Cdd:PRK08133 6 GFDTLAVRAGQLRSPF-GEHSEALFLTSSFvfesaAEAAArfaGEEPGNIYSRFTNPTVTMFQERLAALEGAEACVATAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 91 GVAGIDAIVKS-LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVD 169
Cdd:PRK08133 85 GMAAILAVVMAlLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLTELAD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 170 IEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFqIKSTGAAPGP 249
Cdd:PRK08133 165 IAALAEIAHAAGALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEVFGF-LRTAGPTLSP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 250 MDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEmDKALAV 329
Cdd:PRK08133 244 FNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQHELAKRQQKGGGAIVSFEVKGGR-EAAWRV 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1475498458 330 LDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSR 397
Cdd:PRK08133 323 IDATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVGLEDVADIKADLARGLAA 390
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
19-395 |
1.15e-123 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 363.99 E-value: 1.15e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPgEHK---------GHEYSRVSNPTRTALEGNLASLEGAEHGIAFS 89
Cdd:TIGR01326 1 HFETLQLHAGQEPDPTTGSRAVPIYQTTSYVFDST-EHAaalfglqepGNIYSRLMNPTTDVLEQRIAALEGGVAALAVA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 90 SGVAGID-AIVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLV 168
Cdd:TIGR01326 80 SGQAAITyAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 169 DIEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCT------NSDEWAE-------- 234
Cdd:TIGR01326 160 DIEAIAEVAHRHGIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVDggkfdwNNGRFPLfttpdpsy 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 235 ----------------KLRFQ-IKSTGAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSH 297
Cdd:TIGR01326 240 hglvftetlgnpafilKARVQlLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGLASH 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 298 PGHALAQKQMSD-YGGMISFELADDeMDKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIR 376
Cdd:TIGR01326 320 PHHALAKKYLPKgFGAVLSFEIKGG-REAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGLIR 398
|
410
....*....|....*....
gi 1475498458 377 LSVGVESFEDLRDDLDRAL 395
Cdd:TIGR01326 399 LSVGIENIDDIIADLEQAL 417
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
19-398 |
7.33e-123 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 360.98 E-value: 7.33e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPSTGAVMTPIYQTSTYA--------QAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSS 90
Cdd:PRK08249 8 GVGTKAVWAGEKEYLPYGATQVPVVLSVAYGyddidewyDVALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFST 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 91 GVAGIDAIVKS-LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVD 169
Cdd:PRK08249 88 GMAAISNTLYTfLKPGDRVVSIKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 170 IEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCtNSDEWAEKLRFQIKSTGAAPGP 249
Cdd:PRK08249 168 IERLAAAAKKVGALVVVDNTFATPINQNPLALGADLVIHSATKFLSGHADALGGVVC-GSKELMEQVYHYREINGATMDP 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 250 MDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELAdDEMDKALAV 329
Cdd:PRK08249 247 MSAYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLK-GGMDTVKRL 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1475498458 330 LDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK08249 326 LPKLRYAHRAANLGAVETIYGPARTTSHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFAHL 394
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
5-397 |
1.31e-115 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 342.74 E-value: 1.31e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 5 SLHDDAVLEAPKAdgfgTRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEH 84
Cdd:PRK08776 2 SFRDPTDAPCSAA----TAAVRAGIDRDTAYGAVTPPIVLSSNFSFDGFGNKRQYDYTRSGNPTRDLLGEALAELEGGAG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 85 GIAFSSGVAGIDAIVKSL-RPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNP 163
Cdd:PRK08776 78 GVITATGMGAINLVLNALlQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 164 LMRLVDIEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKST 243
Cdd:PRK08776 158 LLRITDLRFVIEAAHKVGALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWANAL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 244 GAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEM 323
Cdd:PRK08776 238 GLTGSPFDAFLTLRGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELEGGEA 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1475498458 324 dKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSR 397
Cdd:PRK08776 318 -AVRAFVDGLRYFTLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGLAR 390
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
22-395 |
1.14e-113 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 337.20 E-value: 1.14e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDP--STGAVMtpiYQTSTY----AQAA----PGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSG 91
Cdd:TIGR01325 2 TLAVRGGMLRSGfeETAEAL---YLTSGYvydsAAVAakrfAGELPGFVYSRYGNPTVSVFEERLALLEGAEAAVATASG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 92 VAGIDAIVKSL-RPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDI 170
Cdd:TIGR01325 79 MAAIFAALMALlGAGDHVVASRSLFGSCFVVCSEILPRFGVQTVFVDGTDLSAWEAALKPNTKAVFVETPSNPLQELVDI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 171 EALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPM 250
Cdd:TIGR01325 159 AAVAELAHAAGAKVVVDNVFATPLLQQPLKLGADVVVYSATKHIDGQGRVLGGAILGSEEYMDEPVQKLLRHTGPAMSPF 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 251 DCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDemDKALAVL 330
Cdd:TIGR01325 239 NAWVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVYYPGLPSHPQHELAKRQMSGGGTVVTFDLDCR--QAAFKVL 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1475498458 331 DAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRAL 395
Cdd:TIGR01325 317 DAMRLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDGLVRLSVGLEDVDDLIADIDRAL 381
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
22-397 |
5.36e-113 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 335.71 E-value: 5.36e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKS 101
Cdd:PRK08861 8 TIAVRTGIESDSQYHAVVPPIYLSTNYGFPAFGEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSALNLWVSA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 102 -LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAH 180
Cdd:PRK08861 88 lLGPDDLIVAPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDIAELCQKAKAV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 181 DITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGTK 260
Cdd:PRK08861 168 GALVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTKEHAEELAWWGNCIGATGTPFDSYMTLRGIR 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 261 TLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELAdDEMDKALAVLDAAEVFTLAE 340
Cdd:PRK08861 248 TLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFA-GSFEQLKVFVKALALFSLAE 326
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1475498458 341 SLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSR 397
Cdd:PRK08861 327 SLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQAFAK 383
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
37-395 |
2.15e-111 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 334.30 E-value: 2.15e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 37 AVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKSLRPGDHVVATDDLYG 116
Cdd:PLN02509 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYG 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 117 GTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAHDITVAVDNTFATPYLQ 196
Cdd:PLN02509 183 GSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHAQGALVLVDNSIMSPVLS 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 197 QPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRL 276
Cdd:PLN02509 263 RPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKI 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 277 AQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEMDKALavLDAAEVFTLAESLGGVESLIEHPASMT 356
Cdd:PLN02509 343 AMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHL--VETTKYFSIAVSFGSVKSLISMPCFMS 420
|
330 340 350
....*....|....*....|....*....|....*....
gi 1475498458 357 HASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRAL 395
Cdd:PLN02509 421 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
26-396 |
7.20e-110 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 326.78 E-value: 7.20e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 26 HAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKSLRPG 105
Cdd:PRK07269 13 QAGIKSDEATGALVTPLHFSTTYQHPEFGQSTGFDYTRTKNPTRAKLEETLAAIESADYALATSSGMSAIVLAFSVFPVG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 106 DHVVATDDLYGGTYRLLREVFEPLNIqtSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAHDITVA 185
Cdd:PRK07269 93 SKVVAVRDLYGGSFRWFNQQEKEGRF--HFTYANTEEELIAAIEEDTDIVYIETPTNPLMVEFDIEKVAKLAHAKGAKVI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 186 VDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGTKTLHLR 265
Cdd:PRK07269 171 VDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLELYEKLFYNLNTTGAVLSPFDSYLLMRGLKTLSLR 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 266 MEQHCSSARRLAQMLSAHDKVGHVRYPGLpshpghalaqkqmsdyGGMISFELADDemDKALAVLDAAEVFTLAESLGGV 345
Cdd:PRK07269 251 MERSTANAQEVVAFLKKSPAVKEVLYTGK----------------GGMISFKVADE--TRIPHILNSLKVFTFAESLGGV 312
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1475498458 346 ESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALS 396
Cdd:PRK07269 313 ESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLKQALE 363
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
18-397 |
1.01e-108 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 324.55 E-value: 1.01e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 18 DGFGTRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHE--------YSRVSNPTRTALEGNLASLEGAEHGIAFS 89
Cdd:PRK06434 7 NGFNTRAVQSGELRDPRFGNVTTPIFETSTFVYPNSEKEAYMDstrgmpyiYTRWGNPTVQAFEEKYAVLENAEHALSFS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 90 SGVAGIDAIVKSL-RPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVtDAFTEDTALLWVETPTNPLMRLV 168
Cdd:PRK06434 87 SGMGAITSAILSLiKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDTDRLNSL-DFDPSNYDLIYAESITNPTLKVP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 169 DIEALAERAHAHDitVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPG 248
Cdd:PRK06434 166 DIKNVSSFCHEND--VIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERRKTLGSNPD 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 249 PMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLpshpghALAQKQMSDYGGMISFELADDEmdKALA 328
Cdd:PRK06434 244 PIQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDT------EIGKKVLRGFGGMLSFELRSME--DVHK 315
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1475498458 329 VLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSR 397
Cdd:PRK06434 316 FIRNLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENALSK 384
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
22-395 |
4.17e-108 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 323.00 E-value: 4.17e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPSTGAVMTPIYQTSTYAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKS 101
Cdd:PRK08045 7 TIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 102 -LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAH 180
Cdd:PRK08045 87 fLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAREA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 181 DITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGTK 260
Cdd:PRK08045 167 GAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLR 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 261 TLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEmDKALAVLDAAEVFTLAE 340
Cdd:PRK08045 247 TLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDE-QTLRRFLGGLSLFTLAE 325
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1475498458 341 SLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRAL 395
Cdd:PRK08045 326 SLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGF 380
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
20-395 |
6.59e-106 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 319.00 E-value: 6.59e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 20 FGTRAVHAGQQPDPSTGAVMTPIYQTSTY-------AQAAPG-EHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSG 91
Cdd:PRK07812 14 FETKQIHAGQTPDPATNARALPIYQTTSYtfddtdhAAALFGlAEPGNIYTRIMNPTQDVVEQRIAALEGGVAALLLASG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 92 VAGID-AIVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFV-DMSDPDAVTDAFTEDTALLWVETPTNPLMRLVD 169
Cdd:PRK07812 94 QAAETfAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFVeDPDDLDAWRAAVRPNTKAFFAETISNPQIDVLD 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 170 IEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVC---------------TNSD---- 230
Cdd:PRK07812 174 IPGVAEVAHEAGVPLIVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIVdggtfdwtqgrfpgfTTPDpsyh 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 231 ----------EWAEKLRFQI-KSTGAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPG 299
Cdd:PRK07812 254 gvvfaelgppAYALKARVQLlRDLGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLPSSPW 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 300 HALAQKQM-SDYGGMISFELADDeMDKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLS 378
Cdd:PRK07812 334 YERAKRLApKGTGAVLSFELAGG-VEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLVRLA 412
|
410
....*....|....*..
gi 1475498458 379 VGVESFEDLRDDLDRAL 395
Cdd:PRK07812 413 VGIEGIDDILADLEAGF 429
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
21-398 |
9.33e-106 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 316.77 E-value: 9.33e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 21 GTRAVHAGQqpDPSTGAVMTPIYQTSTYAqaAPGEHKgHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVK 100
Cdd:PRK06460 4 ATRTVREDI--DEATGAITTPIYQTTAYH--YPEGEK-YRYSREANPTVLELTKKIVELENAEMGVAFSSGMGAISTTAL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 101 S-LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHA 179
Cdd:PRK06460 79 AlLKPGNSVLVHRDMFGRSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKSKRYDVVFVENITNPLLRVVDITELSKVCKE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 180 HDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSdEWAEKLRFQIKSTGAAPGPMDCFLTLRGT 259
Cdd:PRK06460 159 NGSILIVDATFSTPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYG-KLLNVIDQMRRTLGTSLDPHAAYLTLRGI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 260 KTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDeMDKALAVLDAAEVFTLA 339
Cdd:PRK06460 238 KTLKIRMDVINRNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNGG-QESALKVMKSLKLIIPA 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1475498458 340 ESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK06460 317 QTLGGVNSVISHPATMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRALSTL 375
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
21-398 |
1.66e-105 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 316.24 E-value: 1.66e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 21 GTRAVHAGQQPDPsTGAVMTPIYQTSTYAQaaPGE----HKGHE--YSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAG 94
Cdd:PRK08574 4 GTDAVRGYRGSDP-YGSLQPPIYLTALFRQ--EGEaypsDRGFDlkYSREENPTLRPLEEALAKLEGGVDALAFNSGMAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 95 IDAIVKS-LRPGDHVVATDDLYGGTYRLLREVfEPLNIQTSFVdMSDPDAVTDAFTED-TALLWVETPTNPLMRLVDIEA 172
Cdd:PRK08574 81 ISTLFFSlLKAGDRVVLPMEAYGTTLRLLKSL-EKFGVKVVLA-YPSTEDIIEAIKEGrTKLVFIETMTNPTLKVIDVPE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 173 LAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDC 252
Cdd:PRK08574 159 VAKAAKELGAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVAWSGEFLEELWEWRRRLGTIMQPFEA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 253 FLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSD--YGGMISFELADDEmDKALAVL 330
Cdd:PRK08574 239 YLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKRLFGKdlYGGVVSFRVKGGR-DAVLKFL 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1475498458 331 DAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK08574 318 RSLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQALGSI 385
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
17-396 |
1.07e-101 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 305.77 E-value: 1.07e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 17 ADGFGTRAVHAGQqPDPSTGA-VMTPIYQTSTYaQAAPGEHKG-HEYSRVSNPTRTALEGNLASLEGAEhGIAFSSGVAG 94
Cdd:PRK07582 1 AYGDGTRSVHAGG-PEAVPGEpVLPGPVFAAPY-HLSPGEPTGpDTYGRASNPTWRALEAALGELEGAE-ALVFPSGMAA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 95 IDAIVKS-LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFV---DMSDPDAvtdaftEDTALLWVETPTNPLMRLVDI 170
Cdd:PRK07582 78 ITAVLRAlLRPGDTVVVPADGYYQVRALAREYLAPLGVTVREAptaGMAEAAL------AGADLVLAETPSNPGLDVCDL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 171 EALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPM 250
Cdd:PRK07582 152 AALAAAAHAAGALLVVDNTTATPLGQRPLELGADLVVASDTKALTGHSDLLLGYVAGRDPELMAAVERWRLLAGAIPGPF 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 251 DCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDemDKALAVL 330
Cdd:PRK07582 232 EAWLAHRSLGTLGLRFARQCANALAVAELLAGHPAVRGVRYPGLPGDPAHEVAARQMRRFGGLVSFELADA--AAAERFV 309
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1475498458 331 DAAEVFTLAESLGGVesliehpasmtHASipAEEREKIG--LTDSLIRLSVGVESFEDLRDDLDRALS 396
Cdd:PRK07582 310 AASRLVVAATSFGGV-----------HTS--ADRRARWGdaVPEGFVRLSCGIEDTDDLVADLERALD 364
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
14-395 |
6.58e-100 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 303.58 E-value: 6.58e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 14 APKADGFGTRAVHAGQQPDPSTGAVMTPIYQTSTYA-----QAAP---GEHKGHEYSRVSNPTRTALEGNLASLEGAEHG 85
Cdd:PRK08134 3 GMSPPGFDTLALHAGAAPDPATGARAVPIHLTTSFVfrdsdHAAAlfnLERAGHVYSRISNPTVAVLEERVAALEGGVGA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 86 IAFSSGVAGID-AIVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPL 164
Cdd:PRK08134 83 IATASGQAALHlAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 165 MRLVDIEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCT-NSDEWAEKLRFQ---- 239
Cdd:PRK08134 163 LEVLDIPTVAAIAHEAGVPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLVDgGRFDWEASGKFPelte 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 240 ---------------------------IKSTGAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYP 292
Cdd:PRK08134 243 pyagfhgmvfaeestvaafllrarregLRDFGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 293 GLPSHPGHALAQKQMSD-YGGMISFELADDEmDKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLT 371
Cdd:PRK08134 323 ELESHPDHALAKRLLPRgAGSVFSFDLKGGR-AAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIG 401
|
410 420
....*....|....*....|....
gi 1475498458 372 DSLIRLSVGVESFEDLRDDLDRAL 395
Cdd:PRK08134 402 EGTIRLSIGLEDADDLIDDLKRAL 425
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
22-397 |
7.70e-96 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 293.29 E-value: 7.70e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPSTGAVMTPIYQTSTY--------AQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVA 93
Cdd:PRK08248 11 TLAIHAGQEIDPTTGSRAVPIYQTTSYgfrdsehaANLFSLKEFGNIYTRIMNPTTDVFEKRIAALEGGIGALAVSSGQA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 94 GID-AIVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEA 172
Cdd:PRK08248 91 AITySILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNPKGDVLDIEA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 173 LAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVC-------TNSDEWAE----------- 234
Cdd:PRK08248 171 VAAIAHEHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVdsgkfdwKGSGKFPGltepdpsyhgl 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 235 -------------KLRFQ-IKSTGAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGH 300
Cdd:PRK08248 251 vytdavgeaayitKARVQlLRDLGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSYPGLPSHPSY 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 301 ALAQKQMSD-YGGMISFELADDeMDKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSV 379
Cdd:PRK08248 331 ELAKKYLPKgQGAILTFGIKGG-VEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVTPGLVRLSV 409
|
410
....*....|....*...
gi 1475498458 380 GVESFEDLRDDLDRALSR 397
Cdd:PRK08248 410 GTEAIDDILDDLRQAIRQ 427
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
19-398 |
8.68e-95 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 290.46 E-value: 8.68e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPSTGAVMTPIYQTSTY-------AQAAPG-EHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSS 90
Cdd:PRK05994 7 GFATLAVHAGAQPDPTTGARATPIYQTTSFvfndadhAASLFGlQAFGNIYTRITNPTNAVLEERVAALEGGTAALAVAS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 91 GVAGIDAIVKSL-RPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVD 169
Cdd:PRK05994 87 GHAAQFLVFHTLlQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVTD 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 170 IEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGA-VCTNSDEWAEKLRFQIKST----- 243
Cdd:PRK05994 167 IAAIAEVAHRAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIiVDGGTFDWSKSGKYPMLSEprpey 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 244 --------------------------GAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSH 297
Cdd:PRK05994 247 hglvlhetfgnfafaiaarvlglrdlGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGLPDD 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 298 PGHALAQKQMSDYGGMI-SFELADDeMDKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIR 376
Cdd:PRK05994 327 PYHALAQKYSPKGAGAVfTFGLKGG-YEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVVR 405
|
410 420
....*....|....*....|..
gi 1475498458 377 LSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK05994 406 LSIGIEDVDDIIADLEQALAKA 427
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
22-396 |
3.33e-91 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 281.02 E-value: 3.33e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPSTGAVMTPIYQTSTYAqAAPGEH---------KGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGV 92
Cdd:PRK06084 5 TLAIHAGYSPDPTTKAVAVPIYQTTSYA-FDDTQHgadlfdlkvPGNIYTRIMNPTNDVLEQRVAALEGGVGALAVASGM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 93 AGIDAIVKSL-RPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIE 171
Cdd:PRK06084 84 AAITYAIQTIaEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNIIDIQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 172 ALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSD-EWAE-KLRFQI--------- 240
Cdd:PRK06084 164 ALADAAHRHGVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVDSGKfPWAEhKERFALlntpdpsyh 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 241 ----------------------KSTGAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHP 298
Cdd:PRK06084 244 gvtyteafgpaafigrcrvvplRNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLPDHP 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 299 GHALAQKQMSDY-GGMISFELaDDEMDKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRL 377
Cdd:PRK06084 324 EHELARRYMGGKpASILSFGI-KGGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAGVSRDMVRL 402
|
410
....*....|....*....
gi 1475498458 378 SVGVESFEDLRDDLDRALS 396
Cdd:PRK06084 403 SIGIEHIDDIIADLAQALD 421
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
41-396 |
5.72e-91 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 279.70 E-value: 5.72e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 41 PIYQTSTY----AQAAP----GEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGI-DAIVKSLRPGDHVVAT 111
Cdd:PRK07810 36 ALYLTSGYvyesAAAAEaaftGELDRFVYSRYGNPTVSMFEERLRLIEGAEACFATASGMSAVfTALGALLGAGDRLVAA 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 112 DDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAHDITVAVDNTFA 191
Cdd:PRK07810 116 RSLFGSCFVVCNEILPRWGVETVFVDGEDLSQWEEALSVPTQAVFFETPSNPMQSLVDIAAVSELAHAAGAKVVLDNVFA 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 192 TPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGPMDCFLTLRGTKTLHLRMEQHCS 271
Cdd:PRK07810 196 TPLLQRGLPLGADVVVYSGTKHIDGQGRVLGGAILGDREYIDGPVQKLMRHTGPALSAFNAWVLLKGLETLALRVRHSNA 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 272 SARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEMD---KALAVLDAAEVFTLAESLGGVESL 348
Cdd:PRK07810 276 SALRIAEFLEGHPAVRWVRYPFLPSHPQYDLAKRQMSGGGTVVTFELDAPEDAakkRAFEVLDKLRVIDISNNLGDAKSL 355
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1475498458 349 IEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALS 396
Cdd:PRK07810 356 ITHPATTTHRAMGPEGRAAIGLGDGVVRLSVGLEDTDDLIADLDRALG 403
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
28-398 |
2.78e-89 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 276.17 E-value: 2.78e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 28 GQQPDPSTGAVMTPIYQTSTYA------------------QAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFS 89
Cdd:PRK07049 26 GYDPELSEGAVKPPVFLTSTFVfrsaedgrdffdyvsgrkEPPAGEGAGLVYSRFNHPNSEIVEDRLAVYEGAESAALFS 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 90 SGVAGIDAIVKSL-RPGDHVVATDDLYGGTYRLLREVFEPLNIQT-SFVDMSDPDAVTDAFTEDTA-----LLWVETPTN 162
Cdd:PRK07049 106 SGMSAIATTLLAFvRPGDVILHSQPLYGGTETLLAKTFRNFGVGAvGFADGLSEAAIGAAAEAAAAkgrvsLILIETPAN 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 163 PLMRLVDIEAL------AERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDewaekL 236
Cdd:PRK07049 186 PTNSLVDVAAVrrvadaIEARQGHRPIIACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAGAVLGRKA-----L 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 237 RFQIKSTGAAPG----PMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGL--PSHPGHALAQKQMSDY 310
Cdd:PRK07049 261 IRQVRALRSAIGtqldPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYLPFldPDSAYGAVYKRQCTGA 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 311 GGMISFELADDEmDKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDD 390
Cdd:PRK07049 341 GSTFSFDIKGGQ-AAAFRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHPDDLIAD 419
|
....*...
gi 1475498458 391 LDRALSRV 398
Cdd:PRK07049 420 LAQALDAA 427
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
36-396 |
2.73e-85 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 264.64 E-value: 2.73e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 36 GAVMTPIYQTS-----TYAQAAP---GEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKSL-RPGD 106
Cdd:PRK05968 24 DAVVPPIFQTSlftfdSYDEMEDvyaGEKVRPIYSRGDNPTVRAFEEMLAKLEGAEDARGFASGMAAISSTVLSFvEPGD 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 107 HVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTeDTALLWVETPTNPLMRLVDIEALAERAHAHDITVAV 186
Cdd:PRK05968 104 RIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKALP-GAKLLYLESPTSWVFELQDVAALAALAKRHGVVTMI 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 187 DNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVcTNSDEWAEKLRFQIKS-TGAAPGPMDCFLTLRGTKTLHLR 265
Cdd:PRK05968 183 DNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVV-AGSKEHIARINAEAYPyLGAKLSPFEAWLLLRGLRTLPLR 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 266 MEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALaqkqmSDYGGMISFELADDeMDKAlAVLDAAEVFTLAESLGGV 345
Cdd:PRK05968 262 MKAHEASALEIARRLKAHPVVERVCHPALANHPPAGL-----SGTSGLFSFIFREG-IDVR-AFADALKLFRLGVSWGGH 334
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1475498458 346 ESLIEhPASMThASIPAEER--EKIGLTDSLIRLSVGVESFEDLRDDLDRALS 396
Cdd:PRK05968 335 ESLVV-PAEVV-LQQKAQPNsaARFGVSPRSVRLHVGLEGTEALWADLEQALA 385
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
22-398 |
7.15e-84 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 261.23 E-value: 7.15e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAG----QQPDPSTGAVMTP--IYQTSTYAQAA-PGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAG 94
Cdd:PRK07504 13 TRLVHSGtlrsQFGETSEALFLTQgfVYDTAEAAEARfKGEDPGFIYSRYSNPTVDMFEKRMCALEGAEDARATASGMAA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 95 ID-AIVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEAL 173
Cdd:PRK07504 93 VTaAILCQVKAGDHVVAARALFGSCRYVVETLLPRYGIESTLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVIDIAAV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 174 AERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDlILGAVCTNSDEW-AEKLRFQIKSTGAAPGPMDC 252
Cdd:PRK07504 173 AKIANQAGAKLVVDNVFATPLFQKPLELGAHIVVYSATKHIDGQGR-CLGGVVLSDKAWiEEHLQDYFRHTGPSLSPFNA 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 253 FLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEmDKALAVLDA 332
Cdd:PRK07504 252 WTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVIYPGRADHPQADIIAKQMTGGSTLVAFELKGGK-EAAFRFLNA 330
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1475498458 333 AEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK07504 331 LKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGISEGFLRLSAGLEDTDDLIEDLAAALKKV 396
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
36-396 |
5.34e-82 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 256.54 E-value: 5.34e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 36 GAVMTPIYQTSTY--------AQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKSL-RPGD 106
Cdd:PRK05939 8 GAVHKPIHTSVTYgyedardlIDVFQGKKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFLTLlRAGD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 107 HVVATDDLYGGTYRLLREVFEpLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAERAHAHDITVAV 186
Cdd:PRK05939 88 HLVSSQFLFGNTNSLFGTLRG-LGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERGLLYVV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 187 DNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVC-TNSDEW------AEKLR---------FQIKST-----GA 245
Cdd:PRK05939 167 DNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTdTGLFDWsaypniFPAYRkgdpqqwglTQIRKKglrdmGA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 246 APGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEmdK 325
Cdd:PRK05939 247 TLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFELADGI--D 324
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1475498458 326 ALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALS 396
Cdd:PRK05939 325 CFDFLNRLKLVIKATHLGDTRTLVIPVAPTIYYEMGAERRASMGIADSLIRVSVGIEDEADLIADFEQALD 395
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
19-398 |
7.63e-82 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 257.49 E-value: 7.63e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPSTGAVMTPIYQTSTY--------AQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSS 90
Cdd:PRK05613 13 GFETRSIHAGQSVDSDTSARNLPIYQTTSYvfdsaehaKQRFALEDLGPIYSRLTNPTVEALENRIASLEGGVHAVAFAS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 91 GVAGIDAIVKSL-RPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFV-DMSDPDAVTDAFTEDTALLWVETPTNPLMRLV 168
Cdd:PRK05613 93 GQAAETAAILNLaGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVeNPDDPESWQAAVQPNTKAFFGETFANPQADVL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 169 DIEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVC--------------------TN 228
Cdd:PRK05613 173 DIPAVAEVAHRNQVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIdggkfdwtverdgkpvfpyfVT 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 229 SDEWAEKLRFQ---------------IKSTGAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPG 293
Cdd:PRK05613 253 PDPAYHGLKYAdlgapafglkaraglLRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVAKVNFAG 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 294 LPSHPGHALAQKQMSDY-GGMISFELADDEmDKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTD 372
Cdd:PRK05613 333 LKDSPWYATKEKLGLKYtGSVLSFDIKGGK-DEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGITQ 411
|
410 420
....*....|....*....|....*.
gi 1475498458 373 SLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK05613 412 ATVRLSVGIEDIDDIIADLEGGFAAI 437
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
22-398 |
6.22e-69 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 222.06 E-value: 6.22e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPSTGAVMTPIYQTST----YAQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGI-D 96
Cdd:TIGR01324 1 TRLIHSGRQPRFSQGSVNPPLQRASTvlfdSHAAQRRAKGELTYGRRGTLTHFALQDAMCELEGGAGCYLYPSGLAAVtN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 97 AIVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEALAER 176
Cdd:TIGR01324 81 SILAFVKAGDHVLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITFEIQDIPAIAKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 177 AHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWaEKLRFQIKSTGAAPGPMDCFLTL 256
Cdd:TIGR01324 161 ARNPGIVIMIDNTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIGTVVANARTW-DQLREHSYLMGQMVDADDAYTTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 257 RGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEMDKALAVLDAAEVF 336
Cdd:TIGR01324 240 RGLRTLGVRLKQHQESSLAIAKWLSEQPEVARVLHPALPSCPGHEFWKRDFSGSSGLFSFVLQRLTQKQVHAFLDHLQLF 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1475498458 337 TLAESLGGVESLI--EHPASMTHASIPAEerekigLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:TIGR01324 320 GLGYSWGGYESLAlcNQPELGHRPNIKRN------LEGPLIRVHIGLENVDDLKADLKAGFEAI 377
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
19-396 |
5.74e-67 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 217.75 E-value: 5.74e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPSTGAVMTPIYQTSTY----AQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAG 94
Cdd:PRK05967 12 GINTRLAHDGNDPGDYHGFVNPPVVHASTVlfpdAETMATRGQKYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGLAA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 95 IDA-IVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIEAL 173
Cdd:PRK05967 92 VTVpFLGFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIPAI 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 174 AERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWaEKLRFQIKSTGAAPGPMDCF 253
Cdd:PRK05967 172 AEAAHRHGAIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVSANEKCW-PQLLEAHGTLGLCAGPDDTY 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 254 LTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEMD---KALAVL 330
Cdd:PRK05967 251 QILRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVLAAGPEKgkaKAHAFL 330
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1475498458 331 DAAEVFTLAESLGGVESLiehpasMTHASIPAEEREKIGLTDSLIRLSVGVESFEDLRDDLDRALS 396
Cdd:PRK05967 331 DALEIFGLGYSWGGYESL------ALHVKLGDRTVAKAPYAGPVIRLQIGLEDVPDLKADLERGFA 390
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
22-398 |
1.16e-66 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 216.90 E-value: 1.16e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPSTGAVMTPIYQTST-----YAQAAPGEHKGHEYSRV---SNPTRTALEGNLASLEGAEHGIAFSSGVA 93
Cdd:PRK07050 12 TRIVQPDDQIPPGFRSFVTPVARASTvvfpdLATMRALDWRQDVQWRYglhATPTSLALAQRLAEIEGGRHALLQPSGLA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 94 GID----AIVKSlrpGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVD 169
Cdd:PRK07050 92 AISlvyfGLVKA---GDDVLIPDNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEVPD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 170 IEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWAEKLRFQIKSTGAAPGP 249
Cdd:PRK07050 169 VPAITAAARARGVVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARMRLGIGVSA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 250 MDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFeLADDEMDKAL-- 327
Cdd:PRK07050 249 DDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSV-VFDERYSPAQvd 327
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1475498458 328 AVLDAAEVFTLAESLGGVESL--IEHPASMTHASIPAEERekigltdsLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK07050 328 AFVEALELFAIGWSWGGACSLamPYDVASMRTAKWPHRGT--------LVRLYIGLEDEADLIADLEQALEAA 392
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
61-398 |
7.25e-64 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 210.01 E-value: 7.25e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 61 YSRVSNPTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKSL-RPGDHVVATDDLYGGTYRLLREVF-EPLNIQTSFVDM 138
Cdd:PLN02242 70 YSRHFNPTVLNLGRQMAALEGTEAAYCTASGMSAISSVLLQLcSSGGHVVASNTLYGGTHALLAHFLpRKCNITTTFVDI 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 139 SDPDAVTDAFTE-DTALLWVETPTNPLMRLVDIEALAERAHAHDITVAVDNTFAtPYLQQPLAHGADLVLHSATKYLGGH 217
Cdd:PLN02242 150 TDLEAVKKAVVPgKTKVLYFESISNPTLTVADIPELARIAHEKGVTVVVDNTFA-PMVLSPARLGADVVVHSISKFISGG 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 218 SDLILGAVCTNSDEWAEKLRFQ---IKSTGAAPGPMDCF-LTLRgTKTLHLRMEQHCSSARRLAQMLSahdKVG-HVRYP 292
Cdd:PLN02242 229 ADIIAGAVCGPAELVNSMMDLHhgaLMLLGPTMNPKVAFeLSER-LPHLSLRMKEHCRRAMEYAKRMK---ELGlKVIYP 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 293 GLPSHPGHALAQKQMSD---YGGMISFELADDEmdKALAVLDAAEVFT----LAESLGGVESLIEHPASMTHASIPAEER 365
Cdd:PLN02242 305 GLEDHPQHALLKSMANKgygFGGLLCLDMDTEE--RANRLMRYLQNSTqfgfMAVSLGYYETLMSCSGSSTSSELDPEEK 382
|
330 340 350
....*....|....*....|....*....|....
gi 1475498458 366 EKIGLTDSLIRLSVG-VESFEDLRDDLDRALSRV 398
Cdd:PLN02242 383 AAAGISPGLVRMSVGyTGTLEQRWSQFEKALSAM 416
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
16-397 |
7.23e-61 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 201.50 E-value: 7.23e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 16 KADGFGTRAVHAGQQPDPSTGAVMTPIYQTSTYA--------QAAPGEHKGHE-YSRVSNPTRTALEGNLASLEGAEHGI 86
Cdd:PRK09028 1 MSEKKATKIVSAGRDKKWTKGVINPPVFRASTVVfdtvaemrHAAKNRANGEMfYGRRGTPTHFAFQAAIVELEGGAGTA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 87 AFSSGVAGI-DAIVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLM 165
Cdd:PRK09028 81 LYPSGAAAIsNALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 166 RLVDIEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWaEKLRFQIKSTGA 245
Cdd:PRK09028 161 EVQDVPTLSRIAHEHDIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLGTATANEKHW-DQLREHSYLMGQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 246 APGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEMDK 325
Cdd:PRK09028 240 CTSPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKQGDPKA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1475498458 326 ALAVLDAAEVFTLAESLGGVESLIEHPASMTH-ASIPAEEREKigltdSLIRLSVGVESFEDLRDDLDRALSR 397
Cdd:PRK09028 320 VTALVEGMQHFKMGFSWGGFESLILGVFGINKlRTATNWDFSK-----PLIRLHIGLEDVDDLIADLEAGFER 387
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
19-395 |
9.23e-58 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 194.50 E-value: 9.23e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 19 GFGTRAVHAGQQPDPSTGAVMtPIYQTSTY--------AQAAPGEHKGHEYSRVSNPTRTALEGNLASLEGAEHGIAFSS 90
Cdd:PRK06702 6 GKGTICVQGGYTPKNGEPRVL-PLYQSTTYkydtsddlAALFNLEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 91 GVAGID-AIVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMS-DPDAVTDAFTEDTALLWVETPTNPLMRLV 168
Cdd:PRK06702 85 GQAAIMlAVLNICSSGDHLLCSSTVYGGTFNLFGVSLRKLGIDVTFFNPNlTADEIVALANDKTKLVYAESLGNPAMNVL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 169 DIEALAERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSD-EWAE------------- 234
Cdd:PRK06702 165 NFKEFSDAAKELEVPFIVDNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIDGGNfDWTNgkypelvepdpsy 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 235 ----------------KLRFQ-IKSTGAAPGPMDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSH 297
Cdd:PRK06702 245 hgvsyvqnfgaaayivKARVQlLRDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSN 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 298 PGHALAQKQMSD-YGGMISFELADDeMDKALAVLDAAEVFTLAESLGGVESLIEHPASMTHASIPAEEREKIGLTDSLIR 376
Cdd:PRK06702 325 ENYSLAQKYLKKgASGVLTFGIKGG-LEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIR 403
|
410
....*....|....*....
gi 1475498458 377 LSVGVESFEDLRDDLDRAL 395
Cdd:PRK06702 404 LSVGIEDVSDIIADLEAAL 422
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
22-398 |
3.57e-56 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 189.53 E-value: 3.57e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 22 TRAVHAGQQPDPSTGAVMTPIYQTSTYA--------QAAPGEHKGHE-YSRVSNPTRTALEGNLASLEGAEHGIAFSSGV 92
Cdd:PRK08114 8 TQLVNAGRSKKYTQGSVNSVIQRASSLVfdsveakkHATRNRANGELfYGRRGTLTHFSLQEAMCELEGGAGCALYPCGA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 93 AGI-DAIVKSLRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWVETPTNPLMRLVDIE 171
Cdd:PRK08114 88 AAVaNAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSITMEVHDVP 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 172 AL--AERAHAHDITVAVDNTFATPYLQQPLAHGADLVLHSATKYLGGHSDLILGAVCTNSDEWaEKLRFQIKSTGAAPGP 249
Cdd:PRK08114 168 AIvaAVRSVNPDAVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIGTAVANARCW-EQLRENSYLMGQMVDA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 250 MDCFLTLRGTKTLHLRMEQHCSSARRLAQMLSAHDKVGHVRYPGLPSHPGHALAQKQMSDYGGMISFELADDEMDKALA- 328
Cdd:PRK08114 247 DTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKKLTDEQLAn 326
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1475498458 329 VLDAAEVFTLAESLGGVESLIEHPASMTHASI-PAEEREkigLTDSLIRLSVGVESFEDLRDDLDRALSRV 398
Cdd:PRK08114 327 YLDNFSLFSMAYSWGGFESLILANQPEEIAAIrPAGEVD---FTGTLIRLHIGLEDVDDLIADLAAGFARI 394
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
69-228 |
5.32e-10 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 57.78 E-value: 5.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 69 RTALEGNLASL--EGAEHGIAFSSGVAGIDAIVKSLR-PGDHVVATDDLYGGTYRLLREVFEPlniQTSFVDMSDPDAVT 145
Cdd:cd01494 2 LEELEEKLARLlqPGNDKAVFVPSGTGANEAALLALLgPGDEVIVDANGHGSRYWVAAELAGA---KPVPVPVDDAGYGG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 146 DAF--------TEDTALLWVETPTNPLMRLVDIEALAERAHAHDITVAVDNTFATPY----LQQPLAHGADLVLHSATKY 213
Cdd:cd01494 79 LDVaileelkaKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGAspapGVLIPEGGADVVTFSLHKN 158
|
170
....*....|....*
gi 1475498458 214 LGGHsdlILGAVCTN 228
Cdd:cd01494 159 LGGE---GGGVVIVK 170
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
82-247 |
5.17e-09 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 57.35 E-value: 5.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 82 AEHGIAFSSGVAGIDAIVKSL-RPGDHVVATD---DLYGGTYRLLREVFEPLNIQTSFVDMSDPDAVTDAFTEDTALLWV 157
Cdd:cd00609 59 PEEIVVTNGAQEALSLLLRALlNPGDEVLVPDptyPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLEAAKTPKTKLLYL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 158 ETPTNP---LMRLVDIEALAERAHAHDITVAVDNTFA--------TPYLQQPLAHGADLVLHSATKYLgGHSDLILGAVC 226
Cdd:cd00609 139 NNPNNPtgaVLSEEELEELAELAKKHGILIISDEAYAelvydgepPPALALLDAYERVIVLRSFSKTF-GLPGLRIGYLI 217
|
170 180
....*....|....*....|.
gi 1475498458 227 TNSDEWAEKLRFQIKSTGAAP 247
Cdd:cd00609 218 APPEELLERLKKLLPYTTSGP 238
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
71-238 |
3.64e-07 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 51.61 E-value: 3.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 71 ALEGNLASLEGAEHGIAFSSGVAGIDAIVKSL--RPGDHVVATD----------DLYGGTyrllrEVF---EP--LNIqt 133
Cdd:COG0399 34 EFEEEFAAYLGVKHAVAVSSGTAALHLALRALgiGPGDEVITPAftfvatanaiLYVGAT-----PVFvdiDPdtYNI-- 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 134 sfvdmsDPDAVTDAFTEDT-ALLwvetPTNPLMRLVDIEALAERAHAHDITVAVDNTfatpylqQplAHGADLvlhsATK 212
Cdd:COG0399 107 ------DPEALEAAITPRTkAII----PVHLYGQPADMDAIMAIAKKHGLKVIEDAA-------Q--ALGATY----KGK 163
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1475498458 213 YLGGHSDL---------IL-----GAVCTNSDEWAEKLRF 238
Cdd:COG0399 164 KVGTFGDAgcfsfyptkNLttgegGAVVTNDEELAERARS 203
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
67-279 |
2.03e-06 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 49.20 E-value: 2.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 67 PTRTALEGNLASLEGAEHGIAFSSGVAGIDAIVKSL--RPGDHVVATDDLYGGTYRLLREvfepLNIQTSFVDMS----- 139
Cdd:pfam01041 24 PYVREFERAFAAYLGVKHAIAVSSGTAALHLALRALgvGPGDEVITPSFTFVATANAALR----LGAKPVFVDIDpdtyn 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 140 -DPDAVTDAFTEDT-ALLWVETPTNPlmrlVDIEALAERAHAHDITVAVD--NTFATPYLQQPLAHGADLVLHS--ATKY 213
Cdd:pfam01041 100 iDPEAIEAAITPRTkAIIPVHLYGQP----ADMDAIRAIAARHGLPVIEDaaHALGATYQGKKVGTLGDAATFSfhPTKN 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1475498458 214 L----GghsdlilGAVCTNSDEWAEKLRfQIKSTGAAPGPMDCFLT-LRGTKTlhlRMEQhCSSARRLAQM 279
Cdd:pfam01041 176 LttgeG-------GAVVTNDPELAEKAR-VLRNHGMVRKADKRYWHeVLGYNY---RMTE-IQAAIGLAQL 234
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
86-188 |
3.18e-06 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 48.97 E-value: 3.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 86 IAFSSGVA-GIDAIVKSL-RPGDHVVATD----------DLYGGTYRLLrevfePLNIQTSFvdMSDPDAVTDAFTEDTA 153
Cdd:COG0436 93 ILVTNGAKeALALALLALlNPGDEVLVPDpgypsyraavRLAGGKPVPV-----PLDEENGF--LPDPEALEAAITPRTK 165
|
90 100 110
....*....|....*....|....*....|....*...
gi 1475498458 154 LLWVETPTNP---LMRLVDIEALAERAHAHDITVAVDN 188
Cdd:COG0436 166 AIVLNSPNNPtgaVYSREELEALAELAREHDLLVISDE 203
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
97-230 |
7.71e-05 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 44.36 E-value: 7.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 97 AIVKSLRPGDHVVATDDLY----GGTYRLLREVFEpLNIQTSFVDMS-DPDAVTDAFTEDTALLWVETPTNPL---MRLV 168
Cdd:PRK06225 99 VMRAFLSPGDNAVTPDPGYliidNFASRFGAEVIE-VPIYSEECNYKlTPELVKENMDENTRLIYLIDPLNPLgssYTEE 177
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1475498458 169 DIEALAERAHAHDITVAVDNTFATPYLQQPLAHGAD----LVLHSATKYLgGHSDLILGAVCTNSD 230
Cdd:PRK06225 178 EIKEFAEIARDNDAFLLHDCTYRDFAREHTLAAEYApehtVTSYSFSKIF-GMAGLRIGAVVATPD 242
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
86-187 |
1.14e-04 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 43.97 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 86 IAFSSGV-AGIDAIVKS---LRPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVDMS-----DPDAVTDAFTEDTALL- 155
Cdd:COG0520 80 IIFTRGTtEAINLVAYGlgrLKPGDEILITEMEHHSNIVPWQELAERTGAEVRVIPLDedgelDLEALEALLTPRTKLVa 159
|
90 100 110
....*....|....*....|....*....|....
gi 1475498458 156 --WVetpTNPLMRLVDIEALAERAHAHDITVAVD 187
Cdd:COG0520 160 vtHV---SNVTGTVNPVKEIAALAHAHGALVLVD 190
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
67-187 |
3.10e-04 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 42.60 E-value: 3.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 67 PTRTALEGNLASLEG----AEHGIAFSSGV--AGIDAIVKSLRPGDHVVATD---DLYGGTYRLL--REVFEPLNIQTSF 135
Cdd:PRK09082 71 ALREAIAAKTARLYGrqydADSEITVTAGAteALFAAILALVRPGDEVIVFDpsyDSYAPAIELAggRAVRVALQPPDFR 150
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1475498458 136 VDMsdpDAVTDAFTEDTALLWVETPTNP---LMRLVDIEALAERAHAHDITVAVD 187
Cdd:PRK09082 151 VDW---QRFAAAISPRTRLIILNTPHNPsgtVWSAADMRALWQLIAGTDIYVLSD 202
|
|
| SelA |
COG1921 |
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis]; |
146-216 |
3.19e-04 |
|
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441524 Cd Length: 399 Bit Score: 42.42 E-value: 3.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 146 DAFTEDTA-LLWVET-------PTnplmRLVDIEALAERAHAHDITVAVD------------NTFATPYLQQPLAHGADL 205
Cdd:COG1921 149 AAITENTAaLLKVHTsnyrivgFT----EEVSLAELAELAHEHGLPVIVDlgsgslvdlskyGLPHEPTVQEYLAAGADL 224
|
90
....*....|.
gi 1475498458 206 VLHSATKYLGG 216
Cdd:COG1921 225 VTFSGDKLLGG 235
|
|
| avtA |
PRK09440 |
valine--pyruvate transaminase; Provisional |
147-194 |
2.15e-03 |
|
valine--pyruvate transaminase; Provisional
Pssm-ID: 236517 Cd Length: 416 Bit Score: 39.84 E-value: 2.15e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1475498458 147 AFTEDTALLWVETPTNPLMRLV---DIEALAERAHAHDITVAVDNTFATPY 194
Cdd:PRK09440 175 HIDEDTGAICVSRPTNPTGNVLtdeELEKLDALARQHNIPLLIDNAYGPPF 225
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
81-187 |
3.46e-03 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 39.25 E-value: 3.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 81 GAEHGIAfssgvAGIDAIVKslrPGDHVVATD---DLYGGTYRLLREVFEPLNIQTSFVDMS-DPDAVTDAFTEDTALLW 156
Cdd:PRK07777 93 GATEAIA-----AAVLGLVE---PGDEVLLIEpyyDSYAAVIAMAGAHRVPVPLVPDGRGFAlDLDALRAAVTPRTRALI 164
|
90 100 110
....*....|....*....|....*....|....
gi 1475498458 157 VETPTNP---LMRLVDIEALAERAHAHDITVAVD 187
Cdd:PRK07777 165 VNSPHNPtgtVLTAAELAAIAELAVEHDLLVITD 198
|
|
| GcvP1 |
COG0403 |
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport ... |
103-187 |
4.49e-03 |
|
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain is part of the Pathway/BioSystem: Glycine cleavage
Pssm-ID: 440172 [Multi-domain] Cd Length: 442 Bit Score: 38.86 E-value: 4.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475498458 103 RPGDHVVATDDLYGGTYRLLREVFEPLNIQTSFVD----MSDPDAVTDAFTEDTALLWVETPtNPLMRLVDIEALAERAH 178
Cdd:COG0403 153 KRSNKVLVSEDVHPQTRAVLKTYAEPLGIEVVEVPdedgVTDLEALKALLDDDVAGVLVQYP-NFFGVIEDLRAIAEAAH 231
|
90
....*....|.
gi 1475498458 179 AHDI--TVAVD 187
Cdd:COG0403 232 AAGAlvIVAAD 242
|
|
| PRK00451 |
PRK00451 |
aminomethyl-transferring glycine dehydrogenase subunit GcvPA; |
137-206 |
4.85e-03 |
|
aminomethyl-transferring glycine dehydrogenase subunit GcvPA;
Pssm-ID: 234769 [Multi-domain] Cd Length: 447 Bit Score: 38.97 E-value: 4.85e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1475498458 137 DMSDPDAVTDAFTEDTALLWVETPtNPLMRLVDIEALAERAHAHD-ITVAVDNTFATPYLQQPLAHGADLV 206
Cdd:PRK00451 190 GVTDLEALEAAVDDDTAAVVVQYP-NFFGVIEDLEEIAEIAHAGGaLFIVGVDPVSLGLLKPPGEYGADIV 259
|
|
| |
