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Conserved domains on  [gi|1488020570|ref|WP_120609768|]
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FUSC family protein [Corallococcus sp. CA053C]

Protein Classification

FUSC family protein( domain architecture ID 1001339)

FUSC family protein containing a fusaric acid resistance protein (FUSC_2) domain similar to Escherichia coli inner membrane protein YeeA

Gene Ontology:  GO:0022857
TCDB:  2.A.85.7.1

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
397-644 5.48e-44

Uncharacterized membrane protein YccC [Function unknown];


:

Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 159.79  E-value: 5.48e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 397 AWWAVLGDHLTPQSVIFRHALRLGITATVATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMG 476
Cdd:COG1289    31 RRLKRLRANLSPDSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQPSYGATLSRALQRILGTLLGALAGLL 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 477 LVHVLPAKWMMLAAIVVLVCV-SVSVRPLNFTVFQVLLAPALVLLAEIQS-GDWQLAGVRILNTLLGGALALVGMRLLWP 554
Cdd:COG1289   111 LLALFPQPLLLLLALALVLGLcFFALLTRSYAFALAGITAAVVLLFALLGpGVFDVALARVLDTLIGILIALLVSYLLWP 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 555 SPEHARFPEEVASVLRADRDYLREVARTPVPTES-DLREARRKVGVALLSAEASFQRLLSEWKGPAKelEPGMALITFAR 633
Cdd:COG1289   191 RWARRRLRARLARALRANARYLRALLSQGDPADDlALRAARRRLAAALAALEALLQRALSEPPRGRR--RELRALLALNH 268

                         250
                  ....*....|.
gi 1488020570 634 RFTAAVTALAA 644
Cdd:COG1289   269 RLLSLLSALGA 279
YCCS_YHJK super family cl42872
integral membrane protein, YccS/YhfK family; This model represents two clades of putative ...
 165-710 7.19e-27

integral membrane protein, YccS/YhfK family; This model represents two clades of putative transmembrane proteins including the E. coli YccS and YhfK proteins. The YccS hypothetical equivalog (TIGR01666) is found in beta and gamma proteobacteria, while the smaller YhfK group is only found in E. coli, Salmonella and Yersinia. TMHMM on the 19 hits to this model shows a consensus of 11 transmembrane helices separated into two clusters, an N-terminal cluster of 6 and a central cluster of 5. This would indicate two non-membrane domains one on each side of the membrane


The actual alignment was detected with superfamily member TIGR01667:

Pssm-ID: 130728 [Multi-domain]  Cd Length: 701  Bit Score: 116.48  E-value: 7.19e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 165 QAAYFVAGGLWSMFLGLVLWPLRPYRPARLAIATCYEELANVAEAVAGwpLEGPSRVGTWEAVQRAARMRQSLetARATL 244
Cdd:TIGR01667 132 EPLLILAGTLWYGLLTLIWFLLFPNQPLQESLSRLYRELAEYLEAKSS--LFDPDQHTDPEKALLPLAVRNGK--VVDAL 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 245 GATRQG-----RQEESGRGEHLLV--------LLEDADALSLLLTAMAEALDEAPREGAC-RTARTEAQRaLRSLAVDLR 310
Cdd:TIGR01667 208 NQCKQQllmrlRGNRTDPLTKRMLryyfeaqdIHERASSSHHQYQELQELFEHSDVLFRIqRLLQTQAQA-CQVLARDIL 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 311 GVVGALARGSVPgPSAWDAEGVTRLLAADGGWPEPARSQYAHVAGLLGRLREYSAVALDVASRLEERTPLPERDTQPFAP 390
Cdd:TIGR01667 287 LRQPYYHRLRTE-RALEKQIAALEKIRQNQAPDDLLGQLGYLLDNLQSIDWQLARIARVLATAKPLYARDLLADKQPRGL 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 391 APGherawWAVLGDHLTPQSVIFRHALRLGITATVATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVG 470
Cdd:TIGR01667 366 KDI-----LPRLKSHLTPESPLFRHAVRLSLVVMLGYAILMGTALHLGYWILLTTLFVCQPNYGATRLRLVQRIIGTVVG 440

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 471 SVLAMGLVHVLPAKWMMLAAIVVLVCVSVSVRPLNFTVFQVLLAPALVLLAEIQSGD-WQLAGVRILNTLLGGALALVGM 549
Cdd:TIGR01667 441 LVIGVALHFLIPSLEGQLTLMVITGVAFFAFRSKNYGWATVFITLLVLLCFNLLGLDgEQYILPRLIDTLIGCLIAWGAV 520

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 550 RLLWPSPEHARFPEEVASVLRADRDYLREVAR---TPVPTESDLREARRKVGVALLSAEASFQRLLSEWKGPAKELEPGM 626
Cdd:TIGR01667 521 SYLWPDWQSRLLRKMLHDALEANQRYLRLILSqypQGKPDDLAYRIARRNAHNTDAALSTTLSNMMQEPAFNSHYLEDGF 600

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 627 ALITFARRFTAAVTALAASRAWHP----TSDLGPVVRYASDALEELSQAL------VARRVPGGLRREVPPVEG-TDALA 695
Cdd:TIGR01667 601 RLLTLSHTLLSYISALGAHRERLLnpelAAELLQACEIVAKAIQRCQARLeydeeaLAGDANIMEAQEMQPHEDaAGTLV 680

                         570
                  ....*....|....*
gi 1488020570 696 RTQVSRLVRQLGVLH 710
Cdd:TIGR01667 681 YQQLQLIIGLLPTMH 695
YccC super family cl34218
Uncharacterized membrane protein YccC [Function unknown];
24-282 4.01e-09

Uncharacterized membrane protein YccC [Function unknown];


The actual alignment was detected with superfamily member COG1289:

Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 58.48  E-value: 4.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570  24 HLPRHVAGLFRFQPGRPAVAAGLRTGLALGVPLAVSALLQLPQASWAGMAGLFVALVDKGGpYRTRAHAMGAMTVLGAVV 103
Cdd:COG1289    29 NLRRLKRLRANLSPDSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQPSYGA-TLSRALQRILGTLLGALA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 104 GLII--ALPSPFWVDVALTLCWVTACGFARSFGDTPGILGMLLANLFVVSLALPsHGPGAALMQAAYFVAGGLWSMFLGL 181
Cdd:COG1289   108 GLLLlaLFPQPLLLLLALALVLGLCFFALLTRSYAFALAGITAAVVLLFALLGP-GVFDVALARVLDTLIGILIALLVSY 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 182 VLWPLRPYRPARLAIATCYEELANVAEAVAgwplegpsRVGTWEAVQRAARMRQSLETARATLGATRQGRQEESGRGEHl 261
Cdd:COG1289   187 LLWPRWARRRLRARLARALRANARYLRALL--------SQGDPADDLALRAARRRLAAALAALEALLQRALSEPPRGRR- 257

                         250       260
                  ....*....|....*....|.
gi 1488020570 262 lVLLEDADALSLLLTAMAEAL 282
Cdd:COG1289   258 -RELRALLALNHRLLSLLSAL 277
 
Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
397-644 5.48e-44

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 159.79  E-value: 5.48e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 397 AWWAVLGDHLTPQSVIFRHALRLGITATVATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMG 476
Cdd:COG1289    31 RRLKRLRANLSPDSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQPSYGATLSRALQRILGTLLGALAGLL 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 477 LVHVLPAKWMMLAAIVVLVCV-SVSVRPLNFTVFQVLLAPALVLLAEIQS-GDWQLAGVRILNTLLGGALALVGMRLLWP 554
Cdd:COG1289   111 LLALFPQPLLLLLALALVLGLcFFALLTRSYAFALAGITAAVVLLFALLGpGVFDVALARVLDTLIGILIALLVSYLLWP 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 555 SPEHARFPEEVASVLRADRDYLREVARTPVPTES-DLREARRKVGVALLSAEASFQRLLSEWKGPAKelEPGMALITFAR 633
Cdd:COG1289   191 RWARRRLRARLARALRANARYLRALLSQGDPADDlALRAARRRLAAALAALEALLQRALSEPPRGRR--RELRALLALNH 268

                         250
                  ....*....|.
gi 1488020570 634 RFTAAVTALAA 644
Cdd:COG1289   269 RLLSLLSALGA 279
YCCS_YHJK TIGR01667
integral membrane protein, YccS/YhfK family; This model represents two clades of putative ...
 165-710 7.19e-27

integral membrane protein, YccS/YhfK family; This model represents two clades of putative transmembrane proteins including the E. coli YccS and YhfK proteins. The YccS hypothetical equivalog (TIGR01666) is found in beta and gamma proteobacteria, while the smaller YhfK group is only found in E. coli, Salmonella and Yersinia. TMHMM on the 19 hits to this model shows a consensus of 11 transmembrane helices separated into two clusters, an N-terminal cluster of 6 and a central cluster of 5. This would indicate two non-membrane domains one on each side of the membrane


Pssm-ID: 130728 [Multi-domain]  Cd Length: 701  Bit Score: 116.48  E-value: 7.19e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 165 QAAYFVAGGLWSMFLGLVLWPLRPYRPARLAIATCYEELANVAEAVAGwpLEGPSRVGTWEAVQRAARMRQSLetARATL 244
Cdd:TIGR01667 132 EPLLILAGTLWYGLLTLIWFLLFPNQPLQESLSRLYRELAEYLEAKSS--LFDPDQHTDPEKALLPLAVRNGK--VVDAL 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 245 GATRQG-----RQEESGRGEHLLV--------LLEDADALSLLLTAMAEALDEAPREGAC-RTARTEAQRaLRSLAVDLR 310
Cdd:TIGR01667 208 NQCKQQllmrlRGNRTDPLTKRMLryyfeaqdIHERASSSHHQYQELQELFEHSDVLFRIqRLLQTQAQA-CQVLARDIL 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 311 GVVGALARGSVPgPSAWDAEGVTRLLAADGGWPEPARSQYAHVAGLLGRLREYSAVALDVASRLEERTPLPERDTQPFAP 390
Cdd:TIGR01667 287 LRQPYYHRLRTE-RALEKQIAALEKIRQNQAPDDLLGQLGYLLDNLQSIDWQLARIARVLATAKPLYARDLLADKQPRGL 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 391 APGherawWAVLGDHLTPQSVIFRHALRLGITATVATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVG 470
Cdd:TIGR01667 366 KDI-----LPRLKSHLTPESPLFRHAVRLSLVVMLGYAILMGTALHLGYWILLTTLFVCQPNYGATRLRLVQRIIGTVVG 440

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 471 SVLAMGLVHVLPAKWMMLAAIVVLVCVSVSVRPLNFTVFQVLLAPALVLLAEIQSGD-WQLAGVRILNTLLGGALALVGM 549
Cdd:TIGR01667 441 LVIGVALHFLIPSLEGQLTLMVITGVAFFAFRSKNYGWATVFITLLVLLCFNLLGLDgEQYILPRLIDTLIGCLIAWGAV 520

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 550 RLLWPSPEHARFPEEVASVLRADRDYLREVAR---TPVPTESDLREARRKVGVALLSAEASFQRLLSEWKGPAKELEPGM 626
Cdd:TIGR01667 521 SYLWPDWQSRLLRKMLHDALEANQRYLRLILSqypQGKPDDLAYRIARRNAHNTDAALSTTLSNMMQEPAFNSHYLEDGF 600

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 627 ALITFARRFTAAVTALAASRAWHP----TSDLGPVVRYASDALEELSQAL------VARRVPGGLRREVPPVEG-TDALA 695
Cdd:TIGR01667 601 RLLTLSHTLLSYISALGAHRERLLnpelAAELLQACEIVAKAIQRCQARLeydeeaLAGDANIMEAQEMQPHEDaAGTLV 680

                         570
                  ....*....|....*
gi 1488020570 696 RTQVSRLVRQLGVLH 710
Cdd:TIGR01667 681 YQQLQLIIGLLPTMH 695
YCCS TIGR01666
TIGR01666 family membrane protein; This model represents a clade of sequences from gamma and ...
 399-646 1.10e-22

TIGR01666 family membrane protein; This model represents a clade of sequences from gamma and beta proteobacteria. These proteins are >700 amino acids long and many have been annotated as putative membrane proteins. The gene from Salmonella has been annotated as a putative efflux transporter. The gene from E. coli has the name yccS. [Cell envelope, Other]


Pssm-ID: 130727 [Multi-domain]  Cd Length: 704  Bit Score: 103.40  E-value: 1.10e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 399 WAVLGDHLTPQSVIFRHALRLGITATVATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMGLV 478
Cdd:TIGR01666 367 WARIFSHFTFESPLFRHAVRLSIVLFLGYAIIQFFGFNLGYWILLTTLFVCQPNYSATKVRLRQRIIGTLLGVVIGSPLL 446

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 479 HVLPAKWMMLAAIVVLVCVSVSVRPLNFTVFQVLLAPALVLLAEIQSGDWQLAGVRILNTLLGGALALVGMRLLWPSPEH 558
Cdd:TIGR01666 447 YFNPSLELQLVLVVLTGVLFFAFRSNNYSFATFFITLLVLLCFNVLGEGAAVLLPRLLDTLIGCAIAWAAVSYIWPDWQY 526

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 559 ARFPEEVASVLRADRDYLREVARTPVPTESD---LREARRKVGVALLSAEASFQRLLSEWKGPAKELEPGMALITFARRF 635
Cdd:TIGR01666 527 LQLDKVSHQALRANAVYLLHIISQYQFGKSDdlkYRIARRNAHNYDAALSTTVSNMNNEPVKYKAYLQKGFRLLKLNHSL 606

                         250
                  ....*....|.
gi 1488020570 636 TAAVTALAASR 646
Cdd:TIGR01666 607 LSYISALGAHR 617
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
425-547 8.75e-17

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 77.28  E-value: 8.75e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 425 VATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMGLVHVLPAKWMMLAAIVVLVCVSVSVRPL 504
Cdd:pfam13515   1 LAALIAELLGLPRGYWAPIAAAIVLQPTLGATLRRAVQRILGTVLGVLLGLLLLALLPGPLQLILVVALLGFLAEYLIGR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1488020570 505 NFTVFQVLLAPALVLLAEIQS--GDWQLAGVRILNTLLGGALALV 547
Cdd:pfam13515  81 NYALAQVFVTPLALLLASLAGggGPPELALLRILDTLIGALIALL 125
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
24-282 4.01e-09

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 58.48  E-value: 4.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570  24 HLPRHVAGLFRFQPGRPAVAAGLRTGLALGVPLAVSALLQLPQASWAGMAGLFVALVDKGGpYRTRAHAMGAMTVLGAVV 103
Cdd:COG1289    29 NLRRLKRLRANLSPDSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQPSYGA-TLSRALQRILGTLLGALA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 104 GLII--ALPSPFWVDVALTLCWVTACGFARSFGDTPGILGMLLANLFVVSLALPsHGPGAALMQAAYFVAGGLWSMFLGL 181
Cdd:COG1289   108 GLLLlaLFPQPLLLLLALALVLGLCFFALLTRSYAFALAGITAAVVLLFALLGP-GVFDVALARVLDTLIGILIALLVSY 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 182 VLWPLRPYRPARLAIATCYEELANVAEAVAgwplegpsRVGTWEAVQRAARMRQSLETARATLGATRQGRQEESGRGEHl 261
Cdd:COG1289   187 LLWPRWARRRLRARLARALRANARYLRALL--------SQGDPADDLALRAARRRLAAALAALEALLQRALSEPPRGRR- 257

                         250       260
                  ....*....|....*....|.
gi 1488020570 262 lVLLEDADALSLLLTAMAEAL 282
Cdd:COG1289   258 -RELRALLALNHRLLSLLSAL 277
FUSC-like pfam12805
FUSC-like inner membrane protein yccS; This family has similarities to the fusaric acid ...
 95-269 1.18e-08

FUSC-like inner membrane protein yccS; This family has similarities to the fusaric acid resistance protein family. The proteins are lodged in the inner membrane.


Pssm-ID: 432799  Cd Length: 284  Bit Score: 56.87  E-value: 1.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570  95 AMTVLGAVVGLIIALPSPFWVDVALTLCWVTACGfarSFGD-TPGIL-GMLLANLFVVSLALPSHGpgaALMQAAYFVAG 172
Cdd:pfam12805   8 CFAIASLSVQLLFPYPWLFALGLFLSTFLFTMLG---ALGQrYATIAfATLLVAIYTMLGAFQAPV---WWQQPLLLLAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 173 GLWSMFLGLVLWPLRPYRPARLAIATCYEELANVAEAVAGwpLEGPSRVGTWEA-----VQRAARMRQSLETARATL--G 245
Cdd:pfam12805  82 ALWYGLLSLLWHLLFPNRPVQQSLAELFFALADYLDAKAS--LFDPDRADDPEAyrlalAQRNAKVVAALNAARDSLlrR 159

                         170       180
                  ....*....|....*....|....
gi 1488020570 246 ATRQGRQEESGRGEHLLVLLEDAD 269
Cdd:pfam12805 160 LRGNRGHPDTELGRLLRLYFIAQD 183
 
Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
397-644 5.48e-44

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 159.79  E-value: 5.48e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 397 AWWAVLGDHLTPQSVIFRHALRLGITATVATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMG 476
Cdd:COG1289    31 RRLKRLRANLSPDSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQPSYGATLSRALQRILGTLLGALAGLL 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 477 LVHVLPAKWMMLAAIVVLVCV-SVSVRPLNFTVFQVLLAPALVLLAEIQS-GDWQLAGVRILNTLLGGALALVGMRLLWP 554
Cdd:COG1289   111 LLALFPQPLLLLLALALVLGLcFFALLTRSYAFALAGITAAVVLLFALLGpGVFDVALARVLDTLIGILIALLVSYLLWP 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 555 SPEHARFPEEVASVLRADRDYLREVARTPVPTES-DLREARRKVGVALLSAEASFQRLLSEWKGPAKelEPGMALITFAR 633
Cdd:COG1289   191 RWARRRLRARLARALRANARYLRALLSQGDPADDlALRAARRRLAAALAALEALLQRALSEPPRGRR--RELRALLALNH 268

                         250
                  ....*....|.
gi 1488020570 634 RFTAAVTALAA 644
Cdd:COG1289   269 RLLSLLSALGA 279
YCCS_YHJK TIGR01667
integral membrane protein, YccS/YhfK family; This model represents two clades of putative ...
 165-710 7.19e-27

integral membrane protein, YccS/YhfK family; This model represents two clades of putative transmembrane proteins including the E. coli YccS and YhfK proteins. The YccS hypothetical equivalog (TIGR01666) is found in beta and gamma proteobacteria, while the smaller YhfK group is only found in E. coli, Salmonella and Yersinia. TMHMM on the 19 hits to this model shows a consensus of 11 transmembrane helices separated into two clusters, an N-terminal cluster of 6 and a central cluster of 5. This would indicate two non-membrane domains one on each side of the membrane


Pssm-ID: 130728 [Multi-domain]  Cd Length: 701  Bit Score: 116.48  E-value: 7.19e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 165 QAAYFVAGGLWSMFLGLVLWPLRPYRPARLAIATCYEELANVAEAVAGwpLEGPSRVGTWEAVQRAARMRQSLetARATL 244
Cdd:TIGR01667 132 EPLLILAGTLWYGLLTLIWFLLFPNQPLQESLSRLYRELAEYLEAKSS--LFDPDQHTDPEKALLPLAVRNGK--VVDAL 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 245 GATRQG-----RQEESGRGEHLLV--------LLEDADALSLLLTAMAEALDEAPREGAC-RTARTEAQRaLRSLAVDLR 310
Cdd:TIGR01667 208 NQCKQQllmrlRGNRTDPLTKRMLryyfeaqdIHERASSSHHQYQELQELFEHSDVLFRIqRLLQTQAQA-CQVLARDIL 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 311 GVVGALARGSVPgPSAWDAEGVTRLLAADGGWPEPARSQYAHVAGLLGRLREYSAVALDVASRLEERTPLPERDTQPFAP 390
Cdd:TIGR01667 287 LRQPYYHRLRTE-RALEKQIAALEKIRQNQAPDDLLGQLGYLLDNLQSIDWQLARIARVLATAKPLYARDLLADKQPRGL 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 391 APGherawWAVLGDHLTPQSVIFRHALRLGITATVATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVG 470
Cdd:TIGR01667 366 KDI-----LPRLKSHLTPESPLFRHAVRLSLVVMLGYAILMGTALHLGYWILLTTLFVCQPNYGATRLRLVQRIIGTVVG 440

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 471 SVLAMGLVHVLPAKWMMLAAIVVLVCVSVSVRPLNFTVFQVLLAPALVLLAEIQSGD-WQLAGVRILNTLLGGALALVGM 549
Cdd:TIGR01667 441 LVIGVALHFLIPSLEGQLTLMVITGVAFFAFRSKNYGWATVFITLLVLLCFNLLGLDgEQYILPRLIDTLIGCLIAWGAV 520

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 550 RLLWPSPEHARFPEEVASVLRADRDYLREVAR---TPVPTESDLREARRKVGVALLSAEASFQRLLSEWKGPAKELEPGM 626
Cdd:TIGR01667 521 SYLWPDWQSRLLRKMLHDALEANQRYLRLILSqypQGKPDDLAYRIARRNAHNTDAALSTTLSNMMQEPAFNSHYLEDGF 600

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 627 ALITFARRFTAAVTALAASRAWHP----TSDLGPVVRYASDALEELSQAL------VARRVPGGLRREVPPVEG-TDALA 695
Cdd:TIGR01667 601 RLLTLSHTLLSYISALGAHRERLLnpelAAELLQACEIVAKAIQRCQARLeydeeaLAGDANIMEAQEMQPHEDaAGTLV 680

                         570
                  ....*....|....*
gi 1488020570 696 RTQVSRLVRQLGVLH 710
Cdd:TIGR01667 681 YQQLQLIIGLLPTMH 695
YCCS TIGR01666
TIGR01666 family membrane protein; This model represents a clade of sequences from gamma and ...
 399-646 1.10e-22

TIGR01666 family membrane protein; This model represents a clade of sequences from gamma and beta proteobacteria. These proteins are >700 amino acids long and many have been annotated as putative membrane proteins. The gene from Salmonella has been annotated as a putative efflux transporter. The gene from E. coli has the name yccS. [Cell envelope, Other]


Pssm-ID: 130727 [Multi-domain]  Cd Length: 704  Bit Score: 103.40  E-value: 1.10e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 399 WAVLGDHLTPQSVIFRHALRLGITATVATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMGLV 478
Cdd:TIGR01666 367 WARIFSHFTFESPLFRHAVRLSIVLFLGYAIIQFFGFNLGYWILLTTLFVCQPNYSATKVRLRQRIIGTLLGVVIGSPLL 446

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 479 HVLPAKWMMLAAIVVLVCVSVSVRPLNFTVFQVLLAPALVLLAEIQSGDWQLAGVRILNTLLGGALALVGMRLLWPSPEH 558
Cdd:TIGR01666 447 YFNPSLELQLVLVVLTGVLFFAFRSNNYSFATFFITLLVLLCFNVLGEGAAVLLPRLLDTLIGCAIAWAAVSYIWPDWQY 526

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 559 ARFPEEVASVLRADRDYLREVARTPVPTESD---LREARRKVGVALLSAEASFQRLLSEWKGPAKELEPGMALITFARRF 635
Cdd:TIGR01666 527 LQLDKVSHQALRANAVYLLHIISQYQFGKSDdlkYRIARRNAHNYDAALSTTVSNMNNEPVKYKAYLQKGFRLLKLNHSL 606

                         250
                  ....*....|.
gi 1488020570 636 TAAVTALAASR 646
Cdd:TIGR01666 607 LSYISALGAHR 617
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
425-547 8.75e-17

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 77.28  E-value: 8.75e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 425 VATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMGLVHVLPAKWMMLAAIVVLVCVSVSVRPL 504
Cdd:pfam13515   1 LAALIAELLGLPRGYWAPIAAAIVLQPTLGATLRRAVQRILGTVLGVLLGLLLLALLPGPLQLILVVALLGFLAEYLIGR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1488020570 505 NFTVFQVLLAPALVLLAEIQS--GDWQLAGVRILNTLLGGALALV 547
Cdd:pfam13515  81 NYALAQVFVTPLALLLASLAGggGPPELALLRILDTLIGALIALL 125
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
412-595 5.65e-14

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 71.17  E-value: 5.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 412 IFRHALRLGITATVATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMGLVHVLPAKWMMLAAI 491
Cdd:COG4129    10 IGLRTLKTALAAALAWLIAELLGLPYPFFAAIAAVLCLQPTVGRSLRRALERILGVLIGALVGVLFFLLLGYGPWQLGLA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 492 VVLVCVSVSVRPLNFTVFQVLLAPALVLLAEIQSGDWQLAGVRILNTLLGGALALVGMRLLWPSPEHARFPEEVASVLRA 571
Cdd:COG4129    90 VLLAILLAVLLKLGEGIVLAAVTALLVLLLGSPDDSLGYALNRLLDTLIGVGVALLVNLLLLPPDPERRLRRAAAELLEE 169

                         170       180
                  ....*....|....*....|....*.
gi 1488020570 572 DRDYLREVARTPVPTESD--LREARR 595
Cdd:COG4129   170 LADILRELLRLRDASDAEeaLKRLRE 195
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
24-282 4.01e-09

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 58.48  E-value: 4.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570  24 HLPRHVAGLFRFQPGRPAVAAGLRTGLALGVPLAVSALLQLPQASWAGMAGLFVALVDKGGpYRTRAHAMGAMTVLGAVV 103
Cdd:COG1289    29 NLRRLKRLRANLSPDSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQPSYGA-TLSRALQRILGTLLGALA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 104 GLII--ALPSPFWVDVALTLCWVTACGFARSFGDTPGILGMLLANLFVVSLALPsHGPGAALMQAAYFVAGGLWSMFLGL 181
Cdd:COG1289   108 GLLLlaLFPQPLLLLLALALVLGLCFFALLTRSYAFALAGITAAVVLLFALLGP-GVFDVALARVLDTLIGILIALLVSY 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 182 VLWPLRPYRPARLAIATCYEELANVAEAVAgwplegpsRVGTWEAVQRAARMRQSLETARATLGATRQGRQEESGRGEHl 261
Cdd:COG1289   187 LLWPRWARRRLRARLARALRANARYLRALL--------SQGDPADDLALRAARRRLAAALAALEALLQRALSEPPRGRR- 257

                         250       260
                  ....*....|....*....|.
gi 1488020570 262 lVLLEDADALSLLLTAMAEAL 282
Cdd:COG1289   258 -RELRALLALNHRLLSLLSAL 277
FUSC-like pfam12805
FUSC-like inner membrane protein yccS; This family has similarities to the fusaric acid ...
 95-269 1.18e-08

FUSC-like inner membrane protein yccS; This family has similarities to the fusaric acid resistance protein family. The proteins are lodged in the inner membrane.


Pssm-ID: 432799  Cd Length: 284  Bit Score: 56.87  E-value: 1.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570  95 AMTVLGAVVGLIIALPSPFWVDVALTLCWVTACGfarSFGD-TPGIL-GMLLANLFVVSLALPSHGpgaALMQAAYFVAG 172
Cdd:pfam12805   8 CFAIASLSVQLLFPYPWLFALGLFLSTFLFTMLG---ALGQrYATIAfATLLVAIYTMLGAFQAPV---WWQQPLLLLAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 173 GLWSMFLGLVLWPLRPYRPARLAIATCYEELANVAEAVAGwpLEGPSRVGTWEA-----VQRAARMRQSLETARATL--G 245
Cdd:pfam12805  82 ALWYGLLSLLWHLLFPNRPVQQSLAELFFALADYLDAKAS--LFDPDRADDPEAyrlalAQRNAKVVAALNAARDSLlrR 159

                         170       180
                  ....*....|....*....|....
gi 1488020570 246 ATRQGRQEESGRGEHLLVLLEDAD 269
Cdd:pfam12805 160 LRGNRGHPDTELGRLLRLYFIAQD 183
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
39-211 3.37e-08

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 54.22  E-value: 3.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570  39 RPAVAAGLRTGLALGVPLAVSALLQLPQASWAGMAGLFVALVDKGGPYRTRAHAMGAmTVLGAVVGLIIA--LPSPFWVd 116
Cdd:COG4129     8 RRIGLRTLKTALAAALAWLIAELLGLPYPFFAAIAAVLCLQPTVGRSLRRALERILG-VLIGALVGVLFFllLGYGPWQ- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 117 vaLTLCWVTACGFARSFGDTPGILGMLLANLFVVSLALPSHGPGAALMQAAYFVAGGLWSMFLGLVLWPLRPYRPARLAI 196
Cdd:COG4129    86 --LGLAVLLAILLAVLLKLGEGIVLAAVTALLVLLLGSPDDSLGYALNRLLDTLIGVGVALLVNLLLLPPDPERRLRRAA 163

                         170
                  ....*....|....*
gi 1488020570 197 ATCYEELANVAEAVA 211
Cdd:COG4129   164 AELLEELADILRELL 178
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
 414-491 7.88e-08

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 55.75  E-value: 7.88e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1488020570 414 RHALRLGITATVATAVAEGLGLNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMGLVHVLP-AKWMMLAAI 491
Cdd:pfam04632   2 LFALKTFLAAMLALYIALRLELPQPYWAMTTVFIVSQPLSGAVLSKSFYRLLGTLVGAAAAVLLVALFVqAPLLFLLAL 80
ALMT pfam11744
Aluminium activated malate transporter;
408-480 1.53e-05

Aluminium activated malate transporter;


Pssm-ID: 432042 [Multi-domain]  Cd Length: 408  Bit Score: 48.12  E-value: 1.53e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1488020570 408 PQSVIfrHALRLGITATVATAV------AEGLGlNHGYWVTITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMGLVHV 480
Cdd:pfam11744   8 PRRVI--HSLKVGLALTLVSLLyfmrplYNGLG-VNAVWAILTVVVVFEFSVGATLSKGLNRGLATLIAGGLAFGVHHL 83
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
 46-483 1.71e-04

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 44.97  E-value: 1.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570  46 LRTGLALGVPLAVSALLQLPQASWAGMAGLFVAlvdkgGPYR--TRAHAMG--AMTVLGAVVGLII---ALPSPFWVDVA 118
Cdd:pfam04632   5 LKTFLAAMLALYIALRLELPQPYWAMTTVFIVS-----QPLSgaVLSKSFYrlLGTLVGAAAAVLLvalFVQAPLLFLLA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 119 LTLcWVTACGFARSFGDTPGILGMLLANLFVVSLALPS-----HGPGAALMQAAYFVAGGLWSMFLGLVLWPLrpyRPAR 193
Cdd:pfam04632  80 LAL-WIGLCLALSLLDRNFRSYAFVLAGYTAAIIGLPAvadpeAIFDIAVARVSEISLGILCAALVSALVFPR---SVGP 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 194 LAIATCYEELANVAEAVAGWPLEGPSRVGTWEAVQRAARMRQSLETARATLGAtrqgrqeESGRGEHLLVLLedADALSL 273
Cdd:pfam04632 156 ALRARLRARLRDALRLAAAALAGAPGAEAFEAARLRLAADILALEALRSHAAF-------ESPRGRARARAL--RRLLAR 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 274 LLTAMAEALDEAPREGACRTARTEAQRALRSLAVDLRGVVGALARGSVPGpsawDAEGVTRLLAADGGWPEPARS-QYAH 352
Cdd:pfam04632 227 MLALLPRLRSLARLLARLRTEGAGTVPELAALLDELAAWEAALAAEALQA----ALAALRARLRALRPALPLDFDtAAEL 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488020570 353 VAGLLGRLREYsavaldVASRLEERTPLPERDTQPFAPAPGHERAWWAVLgdhltpqsvifRHALRLGITATVATAVAEG 432
Cdd:pfam04632 303 LARLADLLAEL------AEALASCRALRHPIAQGARPARLARHRDHGAAL-----------LNGLRAALAILLAGAFWIA 365

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1488020570 433 LGLNHGY-WVTITVIV-VLQPYAGLTAEKGLQRVAGTLVGSVLAMGLV-HVLPA 483
Cdd:pfam04632 366 TGWPSGAtAVLLAAIVcSLFATLDNPAPAARQFLRGTLLAALAALLYLfFVLPH 419
ArAE_1 pfam06081
Aromatic acid exporter family member 1; This family consists of bacterial proteins with three ...
 417-481 5.63e-03

Aromatic acid exporter family member 1; This family consists of bacterial proteins with three transmembrane regions that are purported to be aromatic acid exporters.


Pssm-ID: 428756 [Multi-domain]  Cd Length: 141  Bit Score: 37.93  E-value: 5.63e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1488020570 417 LRLGITATVATAVAEGLGLNhgYWVT--ITVIVVLQPYAGLTAEKGLQRVAGTLVGSVLAMGLVHVL 481
Cdd:pfam06081   8 LKTAIAVTLAIIIAELLGLP--YPVSagIIAILCIQPTKKRSLRTALARFQACVIGAIIAVVFFELF 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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