NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1495510451|ref|WP_121731317|]
View 

MULTISPECIES: CS1 type fimbrial major subunit [Pseudomonas]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Fimbrial_CS1 super family cl04524
CS1 type fimbrial major subunit; Fimbriae, also known as pili, form filaments radiating from ...
 31-140 1.48e-04

CS1 type fimbrial major subunit; Fimbriae, also known as pili, form filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometres. They enable the cell to colonize host epithelia. This family constitutes the major subunits of CS1 like pili, including CS2 and CFA1 from Escherichia coli, and also the Cable type II pilin major subunit from Burkholderia cepacia. The major subunit of CS1 pili is called CooA. Periplasmic CooA is mostly complexed with the assembly protein CooB. In addition, a small pool of CooA multimers, and CooA-CooD complexes exists, but the functional significance is unknown. A member of this family has also been identified in Salmonella typhi and Salmonella enterica.


The actual alignment was detected with superfamily member pfam04449:

Pssm-ID: 446415  Cd Length: 134  Bit Score: 39.73  E-value: 1.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1495510451  31 INIKAEIPTKQFHAQPRDPNFGQDETMTYNTVTG-KLSNLRQTYDLKNTDGSINAYIEGGT--AALYNGASAIPLTISIG 107
Cdd:pfam04449   5 ITVTANIDTTMDMTRADGSALPTPIKLQYNPGTGlKPVKLSTKIESNAATKKVTVYLANPPqlANQTNGSDNIPLSVSLG 84

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1495510451 108 GVVLDGVSKEIAGDVPSNPGMQADMLIVAAAPT 140
Cdd:pfam04449  85 GVALSTASTTTLIGDAKTGSVLKELVVSQKTPG 117
 
Name Accession Description Interval E-value
Fimbrial_CS1 pfam04449
CS1 type fimbrial major subunit; Fimbriae, also known as pili, form filaments radiating from ...
 31-140 1.48e-04

CS1 type fimbrial major subunit; Fimbriae, also known as pili, form filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometres. They enable the cell to colonize host epithelia. This family constitutes the major subunits of CS1 like pili, including CS2 and CFA1 from Escherichia coli, and also the Cable type II pilin major subunit from Burkholderia cepacia. The major subunit of CS1 pili is called CooA. Periplasmic CooA is mostly complexed with the assembly protein CooB. In addition, a small pool of CooA multimers, and CooA-CooD complexes exists, but the functional significance is unknown. A member of this family has also been identified in Salmonella typhi and Salmonella enterica.


Pssm-ID: 427955  Cd Length: 134  Bit Score: 39.73  E-value: 1.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1495510451  31 INIKAEIPTKQFHAQPRDPNFGQDETMTYNTVTG-KLSNLRQTYDLKNTDGSINAYIEGGT--AALYNGASAIPLTISIG 107
Cdd:pfam04449   5 ITVTANIDTTMDMTRADGSALPTPIKLQYNPGTGlKPVKLSTKIESNAATKKVTVYLANPPqlANQTNGSDNIPLSVSLG 84

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1495510451 108 GVVLDGVSKEIAGDVPSNPGMQADMLIVAAAPT 140
Cdd:pfam04449  85 GVALSTASTTTLIGDAKTGSVLKELVVSQKTPG 117
 
Name Accession Description Interval E-value
Fimbrial_CS1 pfam04449
CS1 type fimbrial major subunit; Fimbriae, also known as pili, form filaments radiating from ...
 31-140 1.48e-04

CS1 type fimbrial major subunit; Fimbriae, also known as pili, form filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometres. They enable the cell to colonize host epithelia. This family constitutes the major subunits of CS1 like pili, including CS2 and CFA1 from Escherichia coli, and also the Cable type II pilin major subunit from Burkholderia cepacia. The major subunit of CS1 pili is called CooA. Periplasmic CooA is mostly complexed with the assembly protein CooB. In addition, a small pool of CooA multimers, and CooA-CooD complexes exists, but the functional significance is unknown. A member of this family has also been identified in Salmonella typhi and Salmonella enterica.


Pssm-ID: 427955  Cd Length: 134  Bit Score: 39.73  E-value: 1.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1495510451  31 INIKAEIPTKQFHAQPRDPNFGQDETMTYNTVTG-KLSNLRQTYDLKNTDGSINAYIEGGT--AALYNGASAIPLTISIG 107
Cdd:pfam04449   5 ITVTANIDTTMDMTRADGSALPTPIKLQYNPGTGlKPVKLSTKIESNAATKKVTVYLANPPqlANQTNGSDNIPLSVSLG 84

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1495510451 108 GVVLDGVSKEIAGDVPSNPGMQADMLIVAAAPT 140
Cdd:pfam04449  85 GVALSTASTTTLIGDAKTGSVLKELVVSQKTPG 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH