|
Name |
Accession |
Description |
Interval |
E-value |
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
148-458 |
5.33e-88 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 273.74 E-value: 5.33e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 148 LFIRPDIQNQFGEMRIFLAVLLGFIVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQK 227
Cdd:COG5002 75 LLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERD 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 228 MTKsIKELDEMRQEFVSNVSHEFQSPLSSIQGFSKTLQTE-KMSEEERNYYLQIIEGESKRMSSLCKQLLTLASLDKEEK 306
Cdd:COG5002 155 ITE-LERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGaADDPEERREYLEIILEEAERLSRLVNDLLDLSRLESGEL 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 307 VLQIKEFNLQKQIKDVIFMLEWKWREKDIAVEFDVPD--ITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESS 384
Cdd:COG5002 234 KLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEdpLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQ 313
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1496527954 385 VIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:COG5002 314 VRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLPL 387
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
226-458 |
2.44e-79 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 245.97 E-value: 2.44e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 226 QKMTKSIKELDEMRQEFVSNVSHEFQSPLSSIQGFSKTLQ-TEKMSEEERNYYLQIIEGESKRMSSLCKQLLTLASLDKE 304
Cdd:COG2205 3 EEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLdEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 305 EKVLQIKEFNLQKQIKDVIFMLEWKWREKDIAVEFDVP--DITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELE 382
Cdd:COG2205 83 KLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPpeLPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREG 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1496527954 383 SSVIISISDNGIGMEQEEMDRIFDRFYKVDtaRARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:COG2205 163 DGVRISVSDNGPGIPEEELERIFERFYRGD--NSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPL 236
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
146-458 |
7.96e-75 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 237.88 E-value: 7.96e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 146 YALFIRPDIQNQFGEMRIFLAVLLGFIVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSF 225
Cdd:COG0642 17 LLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 226 QKMTKSIKELDEMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKmsEEERNYYLQIIEGESKRMSSLCKQLLTLASLDKEE 305
Cdd:COG0642 97 LALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEEL--DEEQREYLETILRSADRLLRLINDLLDLSRLEAGK 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 306 KVLQIKEFNLQKQIKDVIFMLEWKWREKDIAVEFDVPD--ITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELES 383
Cdd:COG0642 175 LELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDdlPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRREGD 254
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1496527954 384 SVIISISDNGIGMEQEEMDRIFDRFYKVDtaRARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:COG0642 255 RVRISVEDTGPGIPPEDLERIFEPFFRTD--PSRRGGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTLPL 327
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
120-458 |
1.15e-57 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 198.09 E-value: 1.15e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 120 RLFITGFFDNELINSVGVPVKHGDKQYALFIRPDIQNQFGEMRIFLAVLLGFIVLLSIIFIAIAAGYIVRPIRKFTKATQ 199
Cdd:COG4251 160 LLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLL 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 200 KIASGEYEIELDVKRKDEIGTLSTSFQKMTKSIKELDEMRQE---FVSNVSHEFQSPLSSIQGFSKTLQT---EKMSEEE 273
Cdd:COG4251 240 LLILLLLLLILVLELLELRLELEELEEELEERTAELERSNEEleqFAYVASHDLREPLRKISGFSQLLEEdygDKLDEEG 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 274 RNYyLQIIEGESKRMSSLCKQLLTLASLDKEEkvLQIKEFNLQKQIKDVIFMLEWKWREKDIAVEFDvPDITIQGDENLL 353
Cdd:COG4251 320 REY-LERIRDAAERMQALIDDLLAYSRVGRQE--LEFEPVDLNELLEEVLEDLEPRIEERGAEIEVG-PLPTVRGDPTLL 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 354 HQVWSNIFTNSIKFSNDG--GTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARarNVEGSGLGLSIVQK 431
Cdd:COG4251 396 RQVFQNLISNAIKYSRPGepPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRD--EYEGTGIGLAIVKK 473
|
330 340
....*....|....*....|....*..
gi 1496527954 432 IVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:COG4251 474 IVERHGGRIWVESEPGEGATFYFTLPK 500
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
160-458 |
1.68e-56 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 192.87 E-value: 1.68e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 160 EMRIFLAVLLGFIVLLsIIFIAIAAGY-----IVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQKMTKSIK- 233
Cdd:COG5000 2 GLQILFLLLLLLIALL-LLLLALWLALllarrLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKe 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 234 ---ELDEMR----------------------------------------------------------------------- 239
Cdd:COG5000 81 qreELEERRryletilenlpagvivldadgritlanpaaerllgipleeligkpleellpeldlaellrealergwqeei 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 240 -----------------------------------------QEFVSNVSHEFQSPLSSIQGFSKTLQ---TEKMSE--EE 273
Cdd:COG5000 161 eltrdgrrtllvrasplrddgyvivfdditellraerlaawGELARRIAHEIKNPLTPIQLSAERLRrklADKLEEdrED 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 274 RNYYLQIIEGESKRMSSLCKQLLTLASLDKeekvLQIKEFNLQKQIKDVIFMLEWKWREKDIAVEFDVPD--ITIQGDEN 351
Cdd:COG5000 241 LERALDTIIRQVDRLKRIVDEFLDFARLPE----PQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPdlPEVLADRD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 352 LLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYkvdTARArnvEGSGLGLSIVQK 431
Cdd:COG5000 317 QLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFF---TTKP---KGTGLGLAIVKK 390
|
410 420
....*....|....*....|....*..
gi 1496527954 432 IVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:COG5000 391 IVEEHGGTIELESRPGGGTTFTIRLPL 417
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
146-457 |
4.60e-51 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 176.91 E-value: 4.60e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 146 YALFIRPDIQNQFGEMRIFLAVLLGFIVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSF 225
Cdd:COG4191 37 LLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERDI 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 226 QKMTKSIKELDEMRQ------------EFVSNVSHEFQSPLSSIQGFSKTLQ---TEKMSEEERNYYLQIIEGESKRMSS 290
Cdd:COG4191 117 TELERAEEELRELQEqlvqseklaalgELAAGIAHEINNPLAAILGNAELLRrrlEDEPDPEELREALERILEGAERAAE 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 291 LCKQLLTLASLDKEEKvlqiKEFNLQKQIKDVIFMLEWKWREKDIAVEFDVPD--ITIQGDENLLHQVWSNIFTNSIK-- 366
Cdd:COG4191 197 IVRSLRAFSRRDEEER----EPVDLNELIDEALELLRPRLKARGIEVELDLPPdlPPVLGDPGQLEQVLLNLLINAIDam 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 367 FSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYkvdTARARNvEGSGLGLSIVQKIVELHNGNVSVYSTK 446
Cdd:COG4191 273 EEGEGGRITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFF---TTKPVG-KGTGLGLSISYGIVEKHGGRIEVESEP 348
|
330
....*....|.
gi 1496527954 447 GEGTTVRVELP 457
Cdd:COG4191 349 GGGTTFTITLP 359
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
168-458 |
5.12e-46 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 166.17 E-value: 5.12e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 168 LLGFIVLLSIIFIAIA-AGYIVRPIRKFTKATQKIASGEyEIELDVKRKDEIGTLStsfqkmtksiKELDEMRQE----- 241
Cdd:PRK11100 186 WAGALLLGIALLIGAGvVWWLNRSIRRLTRYADAVTEGK-PVPLPKLGSSELRELA----------QALESMRVKlegka 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 242 ----FVSNVSHEFQSPLSSIQGFSKTLQtEKMSEEERNYYLQIIEGESKRMSSLCKQLLTLASLDKEEKVLQIKEFNLQK 317
Cdd:PRK11100 255 yveqYVQTLTHELKSPLAAIRGAAELLQ-EDPPPEDRARFTGNILTQSARLQQLIDRLLELARLEQRQELEVLEPVALAA 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 318 QIKDVIFMLEWKWREKDIAVEFDVPDITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGME 397
Cdd:PRK11100 334 LLEELVEAREAQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIP 413
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1496527954 398 QEEMDRIFDRFY---KVDTARarnvEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:PRK11100 414 DYALPRIFERFYslpRPANGR----KSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPR 473
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
223-457 |
6.70e-45 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 160.40 E-value: 6.70e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 223 TSFQKMTKSIKELDEMR--QEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYyLQIIEGESKRMSSLCKQLLTLAS 300
Cdd:COG3852 117 TERKRLERELRRAEKLAavGELAAGLAHEIRNPLTGIRGAAQLLERELPDDELREY-TQLIIEEADRLNNLVDRLLSFSR 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 301 LDKEEKvlqiKEFNLQKQIKDVIFMLEwkwRE--KDIAVEFDV-PDI-TIQGDENLLHQVWSNIFTNSIKFSNDGGTIEF 376
Cdd:COG3852 196 PRPPER----EPVNLHEVLERVLELLR---AEapKNIRIVRDYdPSLpEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITI 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 377 FVEELESS----------VIISISDNGIGMEQEEMDRIFDRFYkvdTARArnvEGSGLGLSIVQKIVELHNGNVSVYSTK 446
Cdd:COG3852 269 RTRVERQVtlgglrprlyVRIEVIDNGPGIPEEILDRIFEPFF---TTKE---KGTGLGLAIVQKIVEQHGGTIEVESEP 342
|
250
....*....|.
gi 1496527954 447 GEGTTVRVELP 457
Cdd:COG3852 343 GKGTTFRIYLP 353
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
162-457 |
1.24e-43 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 159.09 E-value: 1.24e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 162 RIFLAVLLGfiVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYEIELDVKRK-DEIGTLSTSFQKMTKSIKELDEMRQ 240
Cdd:TIGR01386 165 WLILIAVLL--VLLTALLGWWITRLGLEPLRRLSAVAARISPESLDQRLDPSRApAELRELAQSFNAMLGRLEDAFQRLS 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 241 EFVSNVSHEFQSPLSSIQGfsktlQTEKMSEEERN--YYLQIIEG---ESKRMSSLCKQLLTLASLDKEEKVLQIKEFNL 315
Cdd:TIGR01386 243 QFSADLAHELRTPLTNLLG-----QTQVALSQPRTgeEYREVLESnleELERLSRMVSDMLFLARADNGQLALERVRLDL 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 316 QKQIKDVIFMLEWKWREKDIAVEFDVpDITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIG 395
Cdd:TIGR01386 318 AAELAKVAEYFEPLAEERGVRIRVEG-EGLVRGDPQMFRRAISNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPG 396
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1496527954 396 MEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEgTTVRVELP 457
Cdd:TIGR01386 397 IPPEHLSRLFDRFYRVDPARSNSGEGTGLGLAIVRSIMEAHGGRASAESPDGK-TRFILRFP 457
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
241-458 |
3.64e-40 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 150.51 E-value: 3.64e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 241 EFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERnyYLQIIEGESKRMSSLCKQLLTLAsldkEEKVLQIKEFNLQKQIK 320
Cdd:COG5809 272 ELAAGIAHEIRNPLTSLKGFIQLLKDTIDEEQKT--YLDIMLSELDRIESIISEFLVLA----KPQAIKYEPKDLNTLIE 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 321 DVIFMLEWKWREKDIAVEF----DVPDItiQGDENLLHQVWSNIFTNSIKFSNDGGTIefFVE---ELESSVIISISDNG 393
Cdd:COG5809 346 EVIPLLQPQALLKNVQIELeledDIPDI--LGDENQLKQVFINLLKNAIEAMPEGGNI--TIEtkaEDDDKVVISVTDEG 421
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1496527954 394 IGMEQEEMDRIFDRFYkvdtarARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:COG5809 422 CGIPEERLKKLGEPFY------TTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLPI 480
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
240-457 |
4.33e-40 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 147.24 E-value: 4.33e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 240 QEFVSNVSHEFQSPLSSIQGFSKTLQtEKMSEEERNYYLQIIEGESKRMSSLCKQLLTLASLDKeekvLQIKEFNLQKQI 319
Cdd:COG5807 148 GELAAGIAHEIRNPLTSIKGFLQLLQ-ESREDSEREEYFNIIISEIDRINTIITELLVLSKPKK----FNFKKLNLNDVL 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 320 KDVIFMLEWKWREKDIAVEFDVPD--ITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGME 397
Cdd:COG5807 223 EDVIALLSTEAILKNISIKYDLADdePVINGDKNQLKQVFINLIKNAIEAMETGGNITIKTYVEGDFVVISVKDEGIGIP 302
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 398 QEEMDRIFDRFYKVDTararnvEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:COG5807 303 EEVLEKIGEPFFTTKE------EGTGLGLSICKKIIEEHNGTIEVESKPGKGTTFTIYLP 356
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
348-458 |
1.64e-38 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 135.47 E-value: 1.64e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 348 GDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTaRARNVEGSGLGLS 427
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDK-RSRKIGGTGLGLS 79
|
90 100 110
....*....|....*....|....*....|.
gi 1496527954 428 IVQKIVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:smart00387 80 IVKKLVELHGGEISVESEPGGGTTFTITLPL 110
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
232-458 |
1.86e-37 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 141.69 E-value: 1.86e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 232 IKELDEMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYYLQIIEGESKRMSSLCKQLLTL------ASLDKEE 305
Cdd:PRK11006 197 MHQLEGARRNFFANVSHELRTPLTVLQGYLEMMQDQPLEGALREKALHTMREQTQRMEGLVKQLLTLskieaaPTIDLNE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 306 KVlqikefnlqkqikDVIFMLEWKWRE------KDIAVEFDV-PDITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFV 378
Cdd:PRK11006 277 KV-------------DVPMMLRVLEREaqtlsqGKHTITFEVdNSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRW 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 379 EELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:PRK11006 344 QRVPQGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLPE 423
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
131-458 |
4.73e-37 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 141.45 E-value: 4.73e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 131 LINSVGVPVKHGDKQYALFIRPDIQ------NQFGEMRIFLAVLLGFIVLLsIIFIAIAAGYivRPIRKFTKATQKIASG 204
Cdd:PRK09835 150 MIALPVGPLVDGKPIYTLLIALSIDfhlhyiNDLKNKLIMTASVISLLIVF-IVLLAVHKGH--APIRSVSRQIQNITSK 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 205 EYEIELDVKRKD-EIGTLSTSFQKMTKSIKELDEMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYYLQIIEG 283
Cdd:PRK09835 227 DLDVRLDPQTVPiELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLE 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 284 ESKRMSSLCKQLLTLASLDKEEKVLQIKEFNLQKQIKDVIFMLEWKWREKDIAVEFDVPDITIQGDENLLHQVWSNIFTN 363
Cdd:PRK09835 307 ELTRMAKMVSDMLFLAQADNNQLIPEKKMLDLADEVGKVFDFFEAWAEERGVELRFVGDPCQVAGDPLMLRRAISNLLSN 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 364 SIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHNGNVSVy 443
Cdd:PRK09835 387 ALRYTPAGEAITVRCQEVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAV- 465
|
330
....*....|....*
gi 1496527954 444 STKGEGTTVRVELPK 458
Cdd:PRK09835 466 TSDARGTRFVISLPR 480
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
353-456 |
9.01e-36 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 127.72 E-value: 9.01e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTarARNVEGSGLGLSIVQKI 432
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDK--SREGGGTGLGLAIVRRI 78
|
90 100
....*....|....*....|....
gi 1496527954 433 VELHNGNVSVYSTKGEGTTVRVEL 456
Cdd:cd00075 79 VEAHGGRITVESEPGGGTTFTVTL 102
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
246-458 |
2.27e-35 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 137.17 E-value: 2.27e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 246 VSHEFQSPLSSIQGFsktLQTEKMSEEERNYYLQIIEGESKRMSSLCKQLLTLAsldkEEKVLQIKEFNLQKQIKDVIFM 325
Cdd:COG5805 294 IAHEIRNPLTSIKGF---LQLLQPGIEDKEEYFDIMLSELDRIESIISEFLALA----KPQAVNKEKENINELIQDVVTL 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 326 LEWKWREKDIAVEFDV--PDITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDR 403
Cdd:COG5805 367 LETEAILHNIQIRLELldEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKK 446
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1496527954 404 IFDRFYKVDTararnvEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:COG5805 447 LGEPFFTTKE------KGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPL 495
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
171-457 |
4.59e-35 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 135.92 E-value: 4.59e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 171 FIVLLSIIFIAIAAGYIVR----PIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQKMTKSIKELDEMRQEFVSNV 246
Cdd:PRK10549 168 LIVALSTLLAALATFLLARgllaPVKRLVEGTHKLAAGDFTTRVTPTSRDELGRLAQDFNQLASTLEKNEQMRRDFMADI 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 247 SHEFQSPLSSIQGFSKTLQ--TEKMSEEErnyylqiiegeskrMSSLCKQLLTLASLdkeekVLQIKEFNL--------Q 316
Cdd:PRK10549 248 SHELRTPLAVLRGELEAIQdgVRKFTPES--------------VASLQAEVGTLTKL-----VDDLHQLSLsdegalayR 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 317 KQIKDVIFMLEW-------KWREKDIAVEFDVPD-ITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIIS 388
Cdd:PRK10549 309 KTPVDLVPLLEVaggafreRFASRGLTLQLSLPDsATVFGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQRDKTLRLT 388
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 389 ISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHNGNVSV-YSTKGeGTTVRVELP 457
Cdd:PRK10549 389 FADSAPGVSDEQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAaHSPFG-GVSITVELP 457
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
137-440 |
1.54e-33 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 131.59 E-value: 1.54e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 137 VPVKHGDKQYAL-FIRP------DIQNqfgemRIF--LAVLLGFIVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYE 207
Cdd:PRK09470 136 FSVRDGEDNYQLyLIRPanspqsDFIN-----LLFdrPLLLLLVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLR 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 208 IELDVkrkdEIGTL-----STSFQKMTKSIKELDEMRQEFVSNVSHEFQSPLSSIQgFSKTLQTEKMSEEERnyyLQIIE 282
Cdd:PRK09470 211 QHPEL----ETGPQefrqaGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQ-LATALLRRRQGESKE---LERIE 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 283 GESKRMSSLCKQLLTLAS------LDKEekVLQIKEFnLQKQIKDVIFmlEWKWREKDIAVEFDVPDITIQGDENLLHQV 356
Cdd:PRK09470 283 TEAQRLDSMINDLLVLSRnqqknhLERE--TFKANSL-WSEVLEDAKF--EAEQMGKSLTVSAPPGPWPINGNPNALASA 357
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 357 WSNIFTNSIKFSNDGGTIEFFVEEleSSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVELH 436
Cdd:PRK09470 358 LENIVRNALRYSHTKIEVAFSVDK--DGLTITVDDDGPGVPEEEREQIFRPFYRVDEARDRESGGTGLGLAIVENAIQQH 435
|
....
gi 1496527954 437 NGNV 440
Cdd:PRK09470 436 RGWV 439
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
348-457 |
2.56e-33 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 121.32 E-value: 2.56e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 348 GDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEElESSVIISISDNGIGMEQEEMDRIFDRFYkvdTARARNVEGSGLGLS 427
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSE-GGELTLTVEDNGIGIPPEDLPRIFEPFS---TADKRGGGGTGLGLS 76
|
90 100 110
....*....|....*....|....*....|
gi 1496527954 428 IVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:pfam02518 77 IVRKLVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
225-457 |
1.10e-30 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 123.36 E-value: 1.10e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 225 FQKMTKSIKEL-DEM-RQE-------FVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYYLQIIEGESKRMSSLCKQL 295
Cdd:PRK10364 214 YRRYLRSRQLLqDEMkRKEklvalghLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 296 LTLASLDKeekvLQIKEFNLQKQIKDVIFMLEWKWREKDIAVEFDVPDI--TIQGDENLLHQVWSNIFTNSIKFSNDGGT 373
Cdd:PRK10364 294 LELVKPTH----LALQAVDLNDLINHSLQLVSQDANSREIQLRFTANDTlpEIQADPDRLTQVLLNLYLNAIQAIGQHGV 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 374 IEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYkvdTARArnvEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVR 453
Cdd:PRK10364 370 ISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYF---TTKA---EGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFT 443
|
....
gi 1496527954 454 VELP 457
Cdd:PRK10364 444 LWLP 447
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
241-457 |
6.38e-29 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 119.69 E-value: 6.38e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 241 EFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYyLQIIEGESKRMSSLCKQLLTLASLDKEekvlQIKEFNLQKQIK 320
Cdd:PRK11360 392 ELVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQEY-LSVVLREVDRLNKVIDQLLEFSRPRES----QWQPVSLNALVE 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 321 DVIFMLEWKWREKDIAVEFDV-PDI-TIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVE-ELESSVIISISDNGIGME 397
Cdd:PRK11360 467 EVLQLFQTAGVQARVDFETELdNELpPIWADPELLKQVLLNILINAVQAISARGKIRIRTWqYSDGQVAVSIEDNGCGID 546
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 398 QEEMDRIFDRFYkvdTARARnveGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:PRK11360 547 PELLKKIFDPFF---TTKAK---GTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLP 600
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
1-457 |
4.21e-28 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 115.78 E-value: 4.21e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 1 MKSLYSRFVFMTVGIMLLSSIIGFLlTNVYYQVK--LKPYNseKILTYaeEVKSLYEKQSE-GNQ----EAYLHSI-AKL 72
Cdd:PRK09467 5 PRSSFARTLLLIVTLLFISQVVSYL-VVLNYAILpsLQQFN--KVLAY--EVRLLFTDQLEdGTQlvvpPAFRREIyREL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 73 GYEIYIVDD-QKNGkrIGNAFRKTTISDDTVRKvLNGETfngvstyptrlfitgffdnelinsvGVPVKHGDKQYALFIR 151
Cdd:PRK09467 80 GISLYSNEAaEEAG--LRWAQHYEFLSEQMSQQ-LGGPT-------------------------EVRVEVGKESPIVWIK 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 152 PDIQNQFGeMRI--------FLAVLlgFIVLLSIIFIAIAAGYI-----VRPIRKFTKATQKIASGEYEIELDVKRKDEI 218
Cdd:PRK09467 132 TPLAPNIW-VRVplteihqgDFSPL--FRYTLAIGLLSVAGGWLfiriqNRPLVALEHAALQVGKGEIPPPLREYGASEV 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 219 GTLSTSFQKMTKSIKELDEMRQEFVSNVSHEFQSPLSSIQgfsktLQTEKMSEEErNYYLQIIEGESKRMSSLCKQLLTL 298
Cdd:PRK09467 209 RSVTRAFNQMAAGIKQLEDDRTLLMAGVSHDLRTPLTRIR-----LATEMMSEED-GYLAESINKDIEECNAIIEQFIDY 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 299 ASLDKEEKVLQIkefNLQKQIKDVIfMLEWKWrEKDIAVEFDVPDITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFV 378
Cdd:PRK09467 283 LRTGQEMPMEMA---DLNALLGEVI-AAESGY-EREIETALQPGPIEVPMNPIAIKRALANLVVNAARYGNGWIKVSSGT 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 379 EEleSSVIISISDNGIGMEQEEMDRIFDRFYKVDTARarNVEGSGLGLSIVQKIVELHNGNVSV-YSTKGeGTTVRVELP 457
Cdd:PRK09467 358 EG--KRAWFQVEDDGPGIPPEQLKHLFQPFTRGDSAR--GSSGTGLGLAIVKRIVDQHNGKVELgNSEEG-GLSARAWLP 432
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
343-456 |
1.95e-27 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 105.57 E-value: 1.95e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 343 DITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIIsISDNGIGMEQEEMDRIFDRFYKVDtarARNVEGS 422
Cdd:cd16940 4 DIQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLSADDGAVIR-VEDNGPGIDEEELEALFERFYRSD---GQNYGGS 79
|
90 100 110
....*....|....*....|....*....|....
gi 1496527954 423 GLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVEL 456
Cdd:cd16940 80 GLGLSIVKRIVELHGGQIFLGNAQGGGLEAWVRL 113
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
353-457 |
4.42e-27 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 104.50 E-value: 4.42e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSIKFSNDGG---TIEFFVEELESSVI-ISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSI 428
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEGEvtlRVSLEEEEEDGVQLrFSVEDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 1496527954 429 VQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16922 81 SKKLVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
159-457 |
1.13e-24 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 105.84 E-value: 1.13e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 159 GEMRIFLAVLLGFIVL-LSI-IFIAIaagyivRP----IRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQKMTKSI 232
Cdd:PRK10604 132 HQMRLLDIALLALIGLsLAFpVFLWM------RPhwqdMLKLEAAAQRLGDGHLAERIHFDEGSSLERLGVAFNQMADNI 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 233 KELDEMRQEFVSNVSHEFQSPLSSIQgfSKTLQTEKMSEEERnyylQIIEGESKRMSSLCKQLLTLASLDKEEKVLQIKE 312
Cdd:PRK10604 206 NALIASKKQLIDGIAHELRTPLVRLR--YRLEMSDNLSAAES----QALNRDIGQLEALIEELLTYARLDRPQNELHLSE 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 313 FNLQKQIKDVIfmLEWKWREKDIAVEFDVPDI--TIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEEleSSVIISIS 390
Cdd:PRK10604 280 PDLPAWLSTHL--ADIQAVTPEKTVRLDTPHQgdYGALDMRLMERVLDNLLNNALRYAHSRVRVSLLLDG--NQACLIVE 355
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1496527954 391 DNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:PRK10604 356 DDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWP 422
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
198-457 |
1.24e-24 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 104.65 E-value: 1.24e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 198 TQKIASGEYEIELdVKRKDEIGTLSTSFQKMTKSIKELDEMrqefVSNVSHEFQSPLS-------SIQGFSKTLQTEKMS 270
Cdd:PRK09303 115 PSEIDSGRYSQEL-LQLSDELFVLRQENETLLEQLKFKDRV----LAMLAHDLRTPLTaaslaleTLELGQIDEDTELKP 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 271 EEERNYY------LQIIEgeskRMSslcKQLLTLASLDKEEKVLQIKEFNLQKQIKDVIFMLEWKWREKDIAVEFDVP-D 343
Cdd:PRK09303 190 ALIEQLQdqarrqLEEIE----RLI---TDLLEVGRTRWEALRFNPQKLDLGSLCQEVILELEKRWLAKSLEIQTDIPsD 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 344 I-TIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESS-VIISISDNGIGMEQEEMDRIFDRFYKVDtaRARNVEG 421
Cdd:PRK09303 263 LpSVYADQERIRQVLLNLLDNAIKYTPEGGTITLSMLHRTTQkVQVSICDTGPGIPEEEQERIFEDRVRLP--RDEGTEG 340
|
250 260 270
....*....|....*....|....*....|....*.
gi 1496527954 422 SGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:PRK09303 341 YGIGLSVCRRIVRVHYGQIWVDSEPGQGSCFHFTLP 376
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
121-458 |
3.50e-23 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 101.63 E-value: 3.50e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 121 LFITGFFDNELINSVGVPVKHGDKQYALFIRPDIQNQFGEMRIFLAVLLGFIVLLSIIFIAIAAGYIVRPIRKFTKATQK 200
Cdd:COG2972 115 LSILLLILGLLLIILLLLSLLGWTLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKK 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 201 IASGEYeIELDVKRKDEIGTLSTSFQKMTKSIKEL-DEMRQEFVSNVSHEFQS------P------LSSIQGFSKTLQTE 267
Cdd:COG2972 195 VEKGDL-VRLEVSGNDEIGILARSFNEMVERIKELiEEVYELELEKKEAELKAlqaqinPhflfntLNSIRWLAELEDPE 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 268 KMSE--EERNYYLQIIEGESKRMSSLCKQLLTLasldkeEKVLQIKEFNLQKQikdvifmLEWKWREKDIAVEFDVPDIT 345
Cdd:COG2972 274 EAEEmlEALSKLLRYSLSKGDELVTLEEELELI------KSYLEIQKLRFGDR-------LEVEIEIDEELLDLLIPKLI 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 346 IQgdeNLLhqvwSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDtararnvEGSGLG 425
Cdd:COG2972 341 LQ---PLV----ENAIEHGIEPKEGGGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEELSSKG-------EGRGIG 406
|
330 340 350
....*....|....*....|....*....|....*.
gi 1496527954 426 LSIVQKIVELHNGN---VSVYSTKGEGTTVRVELPK 458
Cdd:COG2972 407 LRNVRERLKLYYGEeygLEIESEPGEGTTVTIRIPL 442
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-457 |
5.51e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 93.16 E-value: 5.51e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSIKFSNDGGT--IEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARArnVEGSGLGLSIVQ 430
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRPprIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHSREE--YEGTGVGLAIVR 78
|
90 100
....*....|....*....|....*..
gi 1496527954 431 KIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16921 79 KIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
168-457 |
3.73e-22 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 99.38 E-value: 3.73e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 168 LLGFIVLLSIIFIAIAAGYIVRP--IRKFTK---ATQKIASGEYEIELDVKRKDEIGTLSTSFQKMTKSIKELDEMRQEF 242
Cdd:COG4192 327 LLLAIALLSLLLAVLINYFYVRRrlVKRLNAlsdAMAAIAAGDLDVPIPVDGNDEIGRIARLLRVFRDQAIEKTQELETE 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 243 VSN------------------------------VSHEFQSPLS--SIQGFSKTLQTEKMSEEERNYYLQIIEGESKRMSS 290
Cdd:COG4192 407 IEErkrieknlrqtqdeliqaakmavvgqtmtsLAHELNQPLNamSMYLFSAKKALEQENYAQLPTSLDKIEGLIERMDK 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 291 LCKQLLTLASldKEEKVLQikEFNLQKQIKDVIFMLEWKWREKDIAVEFDvPDITIQGDENLLHQVWSNIFTNSIKFSND 370
Cdd:COG4192 487 IIKSLRQFSR--KSDTPLQ--PVDLRQVIEQAWELVESRAKPQQITLHIP-DDLMVQGDQVLLEQVLVNLLVNALDAVAT 561
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 371 GGTIEFFVEELESSVIISISDNGIGMeqEEMDRIFDRFYKVDTArarnveGSGLGLSIVQKIVELHNGNVSVYSTKGEGT 450
Cdd:COG4192 562 QPQISVDLLSNAENLRVAISDNGNGW--PLVDKLFTPFTTTKEV------GLGLGLSICRSIMQQFGGDLYLASTLERGA 633
|
....*..
gi 1496527954 451 TVRVELP 457
Cdd:COG4192 634 MVILEFN 640
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-457 |
3.90e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 90.72 E-value: 3.90e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKI 432
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVKHV 80
|
90 100
....*....|....*....|....*
gi 1496527954 433 VELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16952 81 MSRHDARLLIASELGKGSRFTCLFP 105
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
168-454 |
7.34e-22 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 97.41 E-value: 7.34e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 168 LLGFIVLLSIIFIAIaaGYIVRPIRKFTKATQKiASGEYEIELDVKR-KDEIGTLSTSFQKMTKSIKELDEMRQEFVSNV 246
Cdd:PRK10337 168 LVALPIMLIILMVLL--GRELAPLKKLALALRM-RDPDSETPLNATGvPSEVRPLVEALNQLFARTHAMMVRERRFTSDA 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 247 SHEFQSPLSSIQGFSKTLQTEKMSEEERNYYLQIIEGESKRMSSLCKQLLTLASLDKEEKVLQIKEFNLQKQIKDVIFML 326
Cdd:PRK10337 245 AHELRSPLAALKVQTEVAQLSDDDPQARKKALLQLHAGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSAVMDI 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 327 EWKWREKDIAVEFDVPD--ITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELEssviISISDNGIGMEQEEMDRI 404
Cdd:PRK10337 325 YHTAQQAGIDVRLTLNAhpVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARN----FTVRDNGPGVTPEALARI 400
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1496527954 405 FDRFYKvdtARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRV 454
Cdd:PRK10337 401 GERFYR---PPGQEATGSGLGLSIVRRIAKLHGMNVSFGNAPEGGFEAKV 447
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
172-457 |
1.49e-21 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 97.79 E-value: 1.49e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 172 IVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYEIELDVKRKDEIG-----------TLSTSF----QKMTKSIKELD 236
Cdd:PRK15347 306 LVLLTSVLFLLLRRYLAKPLWRFVDIINKTGPAALEPRLPENRLDELGsiakaynqlldTLNEQYdtleNKVAERTQALA 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 237 EMRQ----------EFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEER----------NYYLQIIegeskrmsslcKQLL 296
Cdd:PRK15347 386 EAKQraeqankrksEHLTTISHEIRTPLNGVLGALELLQNTPLTAEQMdladtarqctLSLLAII-----------NNLL 454
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 297 TLASLDKEEKVLQIKEFNLQKQIKDVIFMLEWKWREKDIA----VEFDVPdITIQGDENLLHQVWSNIFTNSIKFSNDGG 372
Cdd:PRK15347 455 DFSRIESGQMTLSLEETALLPLLDQAMLTIQGPAQSKSLTlrtfVGAHVP-LYLHLDSLRLRQILVNLLGNAVKFTETGG 533
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 373 tIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTararNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTV 452
Cdd:PRK15347 534 -IRLRVKRHEQQLCFTVEDTGCGIDIQQQQQIFTPFYQADT----HSQGTGLGLTIASSLAKMMGGELTLFSTPGVGSCF 608
|
....*
gi 1496527954 453 RVELP 457
Cdd:PRK15347 609 SLVLP 613
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
227-456 |
1.50e-21 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 98.12 E-value: 1.50e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 227 KMTKSikeLDEMRQE----------FVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEernyylqiiegeSKRM-------S 289
Cdd:PRK10841 428 KMEES---LQEMAQAaeqasqsksmFLATVSHELRTPLYGIIGNLDLLQTKELPKG------------VDRLvtamnnsS 492
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 290 SLckqLLTLAS--LD--K-EEKVLQI--KEFNLQKQIKDVI---FMLEWKwreKDIA----VEFDVPDItIQGDENLLHQ 355
Cdd:PRK10841 493 SL---LLKIISdiLDfsKiESEQLKIepREFSPREVINHITanyLPLVVK---KRLGlycfIEPDVPVA-LNGDPMRLQQ 565
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 356 VWSNIFTNSIKFSnDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVEL 435
Cdd:PRK10841 566 VISNLLSNAIKFT-DTGCIVLHVRVDGDYLSFRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLINM 644
|
250 260
....*....|....*....|...
gi 1496527954 436 HNGNVSVYSTKGEGT--TVRVEL 456
Cdd:PRK10841 645 MDGDISVDSEPGMGSqfTIRIPL 667
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
349-457 |
4.79e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 87.90 E-value: 4.79e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 349 DENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSI 428
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 1496527954 429 VQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16946 81 CHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
242-457 |
7.11e-21 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 95.90 E-value: 7.11e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 242 FVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYYLQIIEGESKRMSSLCKQLLTLASldKEEKVlqIKEFNLQKQIKD 321
Cdd:PRK13837 453 LASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGARARLIIDQILAFGR--KGERN--TKPFDLSELVTE 528
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 322 VIFMLEWKW-REKDIAVEFDVPDITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVE--------ELESSVI------ 386
Cdd:PRK13837 529 IAPLLRVSLpPGVELDFDQDQEPAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSraklrapkVLSHGVLppgryv 608
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1496527954 387 -ISISDNGIGMEQEEMDRIFDRFYkvdTARARnveGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:PRK13837 609 lLRVSDTGAGIDEAVLPHIFEPFF---TTRAG---GTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDVYLP 674
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-457 |
8.32e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 87.09 E-value: 8.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 352 LLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYkvdTARARNvEGSGLGLSIVQK 431
Cdd:cd16943 3 QLNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFF---TTKPVG-EGTGLGLSLSYR 78
|
90 100
....*....|....*....|....*.
gi 1496527954 432 IVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16943 79 IIQKHGGTIRVASVPGGGTRFTIILP 104
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
171-458 |
9.38e-21 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 93.11 E-value: 9.38e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 171 FIVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYE---IELDVkrkDEIGTLSTS----FQKMTKSIkeldemRQE-- 241
Cdd:PRK10755 69 VMVSLTLLICFQAVRWITRPLAELQKELEARTADNLTpiaIHSST---LEIEAVTSAlnqlVSRLTSTL------DQErl 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 242 FVSNVSHEFQSPLSSIQgfsktLQTEKMSEeernyyLQIIEGES--KRMSSLCK---QLLTLASLDKEEKVLQIKEFNLq 316
Cdd:PRK10755 140 FTADVAHELRTPLAGIR-----LHLELLEK------QHHIDVAPliARLDQMMHtveQLLQLARAGQSFSSGHYQTVKL- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 317 kqIKDVIF--------MLEWkwREKDIAVEFDVPDITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIIS 388
Cdd:PRK10755 208 --LEDVILpsqdelseMLEQ--RQQTLLLPESAADITVQGDATLLRLLLRNLVENAHRYSPEGSTITIKLSQEDGGAVLA 283
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1496527954 389 ISDNGIGMEQEEMDRIFDRFYKVDTARArnveGSGLGLSIVQKIVELHNGNVSVYSTK-GEGTTVRVELPK 458
Cdd:PRK10755 284 VEDEGPGIDESKCGELSKAFVRMDSRYG----GIGLGLSIVSRITQLHHGQFFLQNRQeRSGTRAWVWLPK 350
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
239-457 |
3.32e-20 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 94.03 E-value: 3.32e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 239 RQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYYLQIIEGESKRMSSLCKQLLTLASLDKEEKVLQIKEFNLQKQ 318
Cdd:PRK09959 712 KSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTL 791
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 319 IKDVIFMLEWKWREKDIAVEFD--VPD-ITIQGDENLLHQVWSNIFTNSIKFSNDGG----TIEFFVEELESSVIISISD 391
Cdd:PRK09959 792 VQNTCHSFGAIAASKSIALSCSstFPDhYLVKIDPQAFKQVLSNLLSNALKFTTEGAvkitTSLGHIDDNHAVIKMTIMD 871
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1496527954 392 NGIGMEQEEMDRIFDRFYKvdTARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:PRK09959 872 SGSGLSQEEQQQLFKRYSQ--TSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIP 935
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
164-457 |
4.11e-20 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 93.38 E-value: 4.11e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 164 FLAVLLGfiVLLSIIFiaiaaGY-----IVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQKMTKSIKEL-DE 237
Cdd:PRK11107 181 FLMLLLG--IGLALLF-----AFrlmrdVTGPIRNMVNTVDRIRRGQLDSRVEGNMLGELDMLKNGINAMAMSLSAYhEE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 238 MRQ--------------------------------------EFVSNVSHEFQSPLSSIQGFSK-TLQTEkMSEEERNYyL 278
Cdd:PRK11107 254 MQQnidqatsdlretleqmeiqnveldlakkraqeaariksEFLANMSHELRTPLNGVIGFTRqTLKTP-LTPTQRDY-L 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 279 QIIEGESKRMSSLCKQLLTLASLDKEEKVLQIKEFNLQKQIKDVIFMLEWKWREKD----IAVEFDVPDITIqGDENLLH 354
Cdd:PRK11107 332 QTIERSANNLLAIINDILDFSKLEAGKLVLENIPFSLRETLDEVVTLLAHSAHEKGleltLNIDPDVPDNVI-GDPLRLQ 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 355 QVWSNIFTNSIKFSnDGGTIEFFVEELESS-----VIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIV 429
Cdd:PRK11107 411 QIITNLVGNAIKFT-ESGNIDILVELRALSntkvqLEVQIRDTGIGISERQQSQLFQAFRQADASISRRHGGTGLGLVIT 489
|
330 340
....*....|....*....|....*...
gi 1496527954 430 QKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:PRK11107 490 QKLVNEMGGDISFHSQPNRGSTFWFHLP 517
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-457 |
5.85e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 84.75 E-value: 5.85e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTarARNVEGSGLGLSIVQKI 432
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDN--SRNTEGAGLGLSIAKAI 78
|
90 100
....*....|....*....|....*
gi 1496527954 433 VELHNGNVSvYSTKGEGTTVRVELP 457
Cdd:cd16923 79 IELHGGSAS-AEYDDNHDLFKVRLP 102
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
359-457 |
7.26e-20 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 84.47 E-value: 7.26e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 359 NIFTNSIKFSNDGGTIEFFVEELESS-VIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHN 437
Cdd:cd16925 11 NLLSNAFKFTPDGGRIRCILEKFRLNrFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLSIVKEFVELHG 90
|
90 100
....*....|....*....|
gi 1496527954 438 GNVSVYSTKGEGTTVRVELP 457
Cdd:cd16925 91 GTVTVSDAPGGGALFQVELP 110
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
337-456 |
7.40e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 85.26 E-value: 7.40e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 337 VEFDVPDITI--QGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTA 414
Cdd:cd16947 3 VEINIPDRPIyaNANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDS 82
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1496527954 415 RARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVEL 456
Cdd:cd16947 83 RNSAKQGNGLGLTITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
167-457 |
1.04e-19 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 92.28 E-value: 1.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 167 VLLGFIVLLSIIFIAIAAGY--IVRPIRKFTKATQKIASGEYEIEL----DVKRKDEIGTLSTSF--------------- 225
Cdd:PRK11466 334 LLLGMVSLCALILILWRVVYrsVTRPLAEQTQALQRLLDGDIDSPFpetaGVRELDTIGRLMDAFrsnvhalnrhreqla 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 226 ---QKMTKSIKEL--------------DEMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYyLQIIEGESKRM 288
Cdd:PRK11466 414 aqvKARTAELQELviehrqaraeaekaSQAKSAFLAAMSHEIRTPLYGILGTAQLLADNPALNAQRDD-LRAITDSGESL 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 289 SSLCKQLLTLASLDKEEKVLQIKE--FNLQKQIKDVIFMLEWKWREKDIAVEFDVPDI---TIQGDENLLHQVWSNIFTN 363
Cdd:PRK11466 493 LTILNDILDYSAIEAGGKNVSVSDepFEPRPLLESTLQLMSGRVKGRPIRLATDIADDlptALMGDPRRIRQVITNLLSN 572
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 364 SIKFSnDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARArnveGSGLGLSIVQKIVELHNGNVSVY 443
Cdd:PRK11466 573 ALRFT-DEGSIVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG----GTGLGLTISSRLAQAMGGELSAT 647
|
330
....*....|....
gi 1496527954 444 STKGEGTTVRVELP 457
Cdd:PRK11466 648 STPEVGSCFCLRLP 661
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
242-457 |
1.34e-19 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 91.93 E-value: 1.34e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 242 FVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYyLQIIEGESKRMSSLCKQLLTLASLDKEEKVLQIKEFNLQKQIKD 321
Cdd:PRK11091 286 FISTISHELRTPLNGIVGLSRILLDTELTAEQRKY-LKTIHVSAITLGNIFNDIIDMDKMERRKLQLDNQPIDFTDFLAD 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 322 VI----FMLEWKWREKDIAVEFDVPDItIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGME 397
Cdd:PRK11091 365 LEnlsgLQAEQKGLRFDLEPLLPLPHK-VITDGTRLRQILWNLISNAVKFTQQGGVTVRVRYEEGDMLTFEVEDSGIGIP 443
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1496527954 398 QEEMDRIFDRFYKV-DTARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:PRK11091 444 EDELDKIFAMYYQVkDSHGGKPATGTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIH 504
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-458 |
2.54e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 82.76 E-value: 2.54e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSIKFSNdgGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKI 432
Cdd:cd16949 1 LARALENVLRNALRYSP--SKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*.
gi 1496527954 433 VELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLPA 104
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
331-458 |
2.36e-18 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 86.44 E-value: 2.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 331 REKDIAVEFD----VPDITIqgDENLLHQVWSNIFTNSI----KFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMD 402
Cdd:COG3290 258 RERGIDLTIDidsdLPDLPL--SDTDLVTILGNLLDNAIeaveKLPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLE 335
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1496527954 403 RIFDRfyKVDTARArnvEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELPK 458
Cdd:COG3290 336 KIFER--GFSTKLG---EGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLPK 386
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-457 |
1.42e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 77.87 E-value: 1.42e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSIKFSndGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARarNVEGSGLGLSIVQKI 432
Cdd:cd16950 1 LKRVLSNLVDNALRYG--GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNAR--GTSGTGLGLAIVQRI 76
|
90 100
....*....|....*....|....*
gi 1496527954 433 VELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16950 77 SDAHGGSLTLANRAGGGLCARIELP 101
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
349-457 |
1.44e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 78.10 E-value: 1.44e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 349 DENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARaRNVEGSGLGLSI 428
Cdd:cd16948 2 DAKWLSFIIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGR-NFQESTGMGLYL 80
|
90 100
....*....|....*....|....*....
gi 1496527954 429 VQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16948 81 VKKLCDKLGHKIDVESEVGEGTTFTITFP 109
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
234-457 |
6.68e-17 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 83.55 E-value: 6.68e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 234 ELDEMRQEFVSNVSHEFQSPLSSIQGFSKTLqTEKMSEEERNYYLQIIEGESKRMSS--LCKQLLTLASLdkeekvlQIK 311
Cdd:PRK10490 659 EREQLRNALLAALSHDLRTPLTVLFGQAEIL-TLDLASEGSPHARQASEIRQQVLNTtrLVNNLLDMARI-------QSG 730
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 312 EFNLQKQ-------IKDVIFMLEWKWREKDIAVEFDVPDITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESS 384
Cdd:PRK10490 731 GFNLRKEwltleevVGSALQMLEPGLSGHPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGER 810
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1496527954 385 VIISISDNGIGMEQEEMDRIFDRFYKVDTARArnVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:PRK10490 811 LQLDVWDNGPGIPPGQEQLIFDKFARGNKESA--IPGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLP 881
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
349-455 |
1.22e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 75.58 E-value: 1.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 349 DENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEgSGLGLSI 428
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGH-YGMGLYI 79
|
90 100
....*....|....*....|....*..
gi 1496527954 429 VQKIVELHNGNVSVYSTKGEGTTVRVE 455
Cdd:cd16975 80 AKNLVEKHGGSLIIENSQKGGAEVTVK 106
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
317-456 |
5.82e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 74.21 E-value: 5.82e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 317 KQIKDVIFMLEWKWREKDIAVEFDV-PDITIQGDENLLHQVWSNIFTNSIKFSNdgGTIEFFVEELESSVIISISDNGIG 395
Cdd:cd16954 1 PLLDSLCSALNKVYQRKGVSISLDIsPELRFPGERNDLMELLGNLLDNACKWCL--EFVEVTARQTDGGLHLIVDDDGPG 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1496527954 396 MEQEEMDRIFDRFYKVDTARarnvEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVEL 456
Cdd:cd16954 79 VPESQRSKIFQRGQRLDEQR----PGQGLGLAIAKEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-457 |
4.66e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 70.89 E-value: 4.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSIKFSNDGG------TIEFFVEELESsVIISISDNGIGMEQEEMDRIFDRFYkvdTARArnvEGSGLGL 426
Cdd:cd16920 1 IQQVLINLVRNGIEAMSEGGcerrelTIRTSPADDRA-VTISVKDTGPGIAEEVAGQLFDPFY---TTKS---EGLGMGL 73
|
90 100 110
....*....|....*....|....*....|.
gi 1496527954 427 SIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16920 74 SICRSIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
238-304 |
4.74e-15 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 69.52 E-value: 4.74e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1496527954 238 MRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNyYLQIIEGESKRMSSLCKQLLTLASLDKE 304
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEEQRE-YLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-438 |
8.75e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 70.29 E-value: 8.75e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSIKFS-NDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQK 431
Cdd:cd16953 1 LGQVLRNLIGNAISFSpPDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAFGQHSGLGLSISRQ 80
|
....*..
gi 1496527954 432 IVELHNG 438
Cdd:cd16953 81 IIEAHGG 87
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
238-304 |
1.18e-14 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 68.39 E-value: 1.18e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1496527954 238 MRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNyYLQIIEGESKRMSSLCKQLLTLASLDKE 304
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQRE-YLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
3-456 |
2.86e-14 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 75.15 E-value: 2.86e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 3 SLYSRFVFMTVGIMLLSSIIGFLLTNVYYQVKLKPYNSEKILTYAEEVKSLYEKQSEGNQEAYLHSIAKLGYEIYIVDDQ 82
Cdd:COG2770 48 ALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 83 KNGKR------IGNAFRKTTISDDTVRKVLNGETFNGVSTYPTRLFITGFFDNELINSVGVPVKHGDKQYALFIRPDIQN 156
Cdd:COG2770 128 LAALLalllalALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAA 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 157 QFGEMRIFLAVLLgfIVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQKMTKSIKELD 236
Cdd:COG2770 208 LAALLLLLLLALL--ALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLRESI 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 237 EMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYYLQIIEGESKRMSSLCKQLLTLASLDKEEKVLQIKEFNLQ 316
Cdd:COG2770 286 EEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLAL 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 317 KQIKDVIFMLEWKWREKDIAVEFDVPDITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGM 396
Cdd:COG2770 366 ELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAI 445
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 397 EQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVEL 456
Cdd:COG2770 446 AAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEEL 505
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
349-442 |
3.24e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 68.64 E-value: 3.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 349 DENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVdtARARNVEGS-GLGLS 427
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSL--PRPHSGQKStGLGLA 78
|
90
....*....|....*
gi 1496527954 428 IVQKIVELHNGNVSV 442
Cdd:cd16945 79 FVQEVAQLHGGRITL 93
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
385-457 |
4.10e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 68.56 E-value: 4.10e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1496527954 385 VIISISDNGIGMEQEEMDRIFDRFYkvdTARARNvEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16919 48 VCLEVSDTGSGMPAEVLRRAFEPFF---TTKEVG-KGTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
188-232 |
6.22e-14 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 65.54 E-value: 6.22e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1496527954 188 VRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQKMTKSI 232
Cdd:cd06225 1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
236-299 |
1.03e-13 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 65.70 E-value: 1.03e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1496527954 236 DEMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYYLQIIEGESKRMSSLCKQLLTLA 299
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLS 64
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
209-457 |
1.07e-13 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 73.17 E-value: 1.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 209 ELDV-KRKDEIGTLSTSfQKMtKSIKELdemrqefVSNVSHEFQSPLSSIQGFSKTLQTekMSEEERNYYLQI------I 281
Cdd:PRK13557 141 QLDVsRRRDAEDALRQA-QKM-EALGQL-------TGGIAHDFNNLLQVMSGYLDVIQA--ALSHPDADRGRMarsvenI 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 282 EGESKRMSSLCKQLLTLASLDKeekvLQIKEFNLQKQIKDVIFMLEWKWREkDIAVEFDV-PDI------TIQGDENLLh 354
Cdd:PRK13557 210 RAAAERAATLTQQLLAFARKQR----LEGRVLNLNGLVSGMGELAERTLGD-AVTIETDLaPDLwncridPTQAEVALL- 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 355 qvwsNIFTNSIKFSNDGGTIEFFVEELESS---------------VIISISDNGIGMEQEEMDRIFDRFYkvdTARARNv 419
Cdd:PRK13557 284 ----NVLINARDAMPEGGRVTIRTRNVEIEdedlamyhglppgryVSIAVTDTGSGMPPEILARVMDPFF---TTKEEG- 355
|
250 260 270
....*....|....*....|....*....|....*...
gi 1496527954 420 EGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:PRK13557 356 KGTGLGLSMVYGFAKQSGGAVRIYSEVGEGTTVRLYFP 393
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
164-442 |
1.25e-13 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 72.74 E-value: 1.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 164 FLAVLLGFiVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYEiELDVKRKDEIGTLSTSFQKMTKSIKELDEMRQEFV 243
Cdd:PRK10815 193 FSYVLLAN-LLLVIPLLWLAAWWSLRPIEALAKQVRELEEGERE-QLDPNPPRELTSLVRNLNRLLKNERERYTKYRTTL 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 244 SNVSHEFQSPLSSIQGFSKTLQTEK-MS-EEERNYYLQIIEgeskRMSSLCKQLLTLASLDKEEKVLQIKEFNLQKQIKD 321
Cdd:PRK10815 271 TDLTHSLKTPLAVLQSTLRSLRSGKqMSvEQAEPIMLEQIS----RISQQIGYYLHRASMRSEHNLLSRELHSVAPLLDN 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 322 VIFMLEWKWREKDIAVEFDV-PDITIQGDENLLHQVWSNIFTNSIKFSndggtIEFfVE----ELESSVIISISDNGIGM 396
Cdd:PRK10815 347 LTSALNKVYQRKGVNITLDIsPEITFVGEKNDFMEVMGNVLDNACKYC-----LEF-VEisarQTDEHLHIVVEDDGPGI 420
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1496527954 397 EQEEMDRIFDRFYKVDTARArnveGSGLGLSIVQKIVELHNGNVSV 442
Cdd:PRK10815 421 PESKRELIFDRGQRADTLRP----GQGLGLSVAREITEQYEGKISA 462
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
145-434 |
6.41e-13 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 70.30 E-value: 6.41e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 145 QYALFIRPDIQNQFGEMRIFLAVLLGFIVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTS 224
Cdd:COG3850 100 LLLLLLLLLLLLAAAINRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARA 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 225 FQKMTKSIKEL-DEMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYYLQIIEGESKRMSSLCKQLLTLASLDK 303
Cdd:COG3850 180 FNRMADELQELyAELEEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNIL 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 304 EEKVLQIKEFNLQKQIKDVIFMLEWKWREKDIAVEFDVPDITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELES 383
Cdd:COG3850 260 AGLLELLLALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAA 339
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1496527954 384 SVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKIVE 434
Cdd:COG3850 340 LLELASILALQAALEAAAAGAALAAAAAAAGLARALAQAGADAAEALGLLA 390
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
349-457 |
5.07e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 62.17 E-value: 5.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 349 DENLLHQVWSNIFTN---SIKFSNDG-GTIEFFVE-ELESSVIISISDNGIGMEQEEMDRIFDRFYkvdTARARnveGSG 423
Cdd:cd16944 1 DTTQISQVLTNILKNaaeAIEGRPSDvGEVRIRVEaDQDGRIVLIVCDNGKGFPREMRHRATEPYV---TTRPK---GTG 74
|
90 100 110
....*....|....*....|....*....|....
gi 1496527954 424 LGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16944 75 LGLAIVKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
344-457 |
8.52e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 61.53 E-value: 8.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 344 ITIQGdeNLLhqvwSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARnvegsG 423
Cdd:cd16915 2 ITIVG--NLI----DNALDALAATGAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKGQGER-----G 70
|
90 100 110
....*....|....*....|....*....|....
gi 1496527954 424 LGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16915 71 IGLALVRQSVERLGGSITVESEPGGGTTFSIRIP 104
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
387-457 |
1.27e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 61.26 E-value: 1.27e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1496527954 387 ISISDNGIGMEQEEMDRIFDRFYkvdTARarnVEGSGLGLSIVQKIVELHNGNVSVYSTKGEgTTVRVELP 457
Cdd:cd16918 46 VSVIDNGPGIPPDLQDTIFYPMV---SGR---ENGTGLGLAIAQNIVSQHGGVIECDSQPGH-TVFSVSLP 109
|
|
| HAMP |
pfam00672 |
HAMP domain; |
182-234 |
2.07e-11 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 58.79 E-value: 2.07e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1496527954 182 IAAGYIVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQKMTKSIKE 234
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
331-457 |
2.75e-11 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 63.48 E-value: 2.75e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 331 REKDIAVEFDVPDitiqGDENLLHQVWSNIF-------TNSIKFSNdGGTIEFFVEELESSVIISISDNGIGMEQEEmdr 403
Cdd:COG4585 138 RAAGIRVELDVDG----DPDRLPPEVELALYrivqealTNALKHAG-ATRVTVTLEVDDGELTLTVRDDGVGFDPEA--- 209
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1496527954 404 ifdrfykvdtararnVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:COG4585 210 ---------------APGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRATLP 248
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-457 |
3.63e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 59.75 E-value: 3.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSIKFSNDggTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTARARNVEGSGLGLSIVQKI 432
Cdd:cd16939 1 MARALDNLLRNALRYAHR--TVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRV 78
|
90 100
....*....|....*....|....*
gi 1496527954 433 VELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16939 79 ALWHGGHVECDDSELGGACFRLTWP 103
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
186-237 |
1.14e-10 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 56.87 E-value: 1.14e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1496527954 186 YIVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQKMTKSIKELDE 237
Cdd:smart00304 2 RLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
240-457 |
8.54e-10 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 60.09 E-value: 8.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 240 QEFVSNVSHEFQSPLSSIQGFSKTLqtEKM-SEEERNYYLQIIEGESKRMSSLCKQLL--------TLASLDK-EEKVLQ 309
Cdd:PRK11073 131 RDLVRGLAHEIKNPLGGLRGAAQLL--SKAlPDPALTEYTKVIIEQADRLRNLVDRLLgpqrpgthVTESIHKvAERVVQ 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 310 IKEFNLQKQIKDVifmlewkwREKDIAVefdvPDITIQGDEnlLHQVWSNIFTNSIK-FSNDGGTIEFFVEELESSVI-- 386
Cdd:PRK11073 209 LVSLELPDNVRLI--------RDYDPSL----PELAHDPDQ--IEQVLLNIVRNALQaLGPEGGTITLRTRTAFQLTLhg 274
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1496527954 387 --------ISISDNGIGMEQEEMDRIFdrfYKVDTARArnvEGSGLGLSIVQKIVELHNGNVSVYSTKGEgTTVRVELP 457
Cdd:PRK11073 275 eryrlaarIDIEDNGPGIPPHLQDTLF---YPMVSGRE---GGTGLGLSIARNLIDQHSGKIEFTSWPGH-TEFSVYLP 346
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
153-247 |
1.79e-09 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 59.65 E-value: 1.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 153 DIQNQFGEMRIFLAVLLGFIVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQKMTKSI 232
Cdd:COG0840 172 LALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIENL 251
|
90
....*....|....*
gi 1496527954 233 KELDEMRQEFVSNVS 247
Cdd:COG0840 252 RELVGQVRESAEQVA 266
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
295-457 |
1.88e-09 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 59.54 E-value: 1.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 295 LLTLASLDK-EEKVLQI-----KEFN-LQKQIKD-VI--FMLEWKWREKD------IAVEFDVPDItiqGDENLLHQ--- 355
Cdd:PRK11086 360 LLHLKSYDQlEDYILKTannyqEEIGsLLGKIKSpVIagFLLGKISRARElgitliISEDSQLPDS---GDEDQVHElit 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 356 VWSNIFTNSIKF--SNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKVDTararnvEGSGLGLSIVQKIV 433
Cdd:PRK11086 437 ILGNLIENALEAvgGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTKG------SNRGVGLYLVKQSV 510
|
170 180
....*....|....*....|....
gi 1496527954 434 ELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:PRK11086 511 ENLGGSIAVESEPGVGTQFFVQIP 534
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-456 |
2.76e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 54.39 E-value: 2.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 353 LHQVWSNIFTNSI----KFSNdgGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFYKvdtarARNV-EGSGLGLS 427
Cdd:cd16976 1 IQQVLMNLLQNALdamgKVEN--PRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFT-----TKPVgKGTGLGLS 73
|
90 100
....*....|....*....|....*....
gi 1496527954 428 IVQKIVELHNGNVSVYSTKGEGTTVRVEL 456
Cdd:cd16976 74 ISYGIVEEHGGRLSVANEEGAGARFTFDL 102
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
331-457 |
5.96e-08 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 54.91 E-value: 5.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 331 REKDIAVEFDVPDITIQGD----------EnllhqvwsnIFTNSIKF---SNDGGTIEFFVEELESSVIISISDNGIGME 397
Cdd:COG3920 377 GGRGIRIELDGPDVELPADaavplglilnE---------LVTNALKHaflSGEGGRIRVSWRREDGRLRLTVSDNGVGLP 447
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 398 QEemdrifdrfykVDTARarnveGSGLGLSIVQKIVELHNGNVSVYStkGEGTTVRVELP 457
Cdd:COG3920 448 ED-----------VDPPA-----RKGLGLRLIRALVRQLGGTLELDR--PEGTRVRITFP 489
|
|
| PRK10935 |
PRK10935 |
nitrate/nitrite two-component system sensor histidine kinase NarQ; |
157-230 |
8.00e-07 |
|
nitrate/nitrite two-component system sensor histidine kinase NarQ;
Pssm-ID: 236800 [Multi-domain] Cd Length: 565 Bit Score: 51.39 E-value: 8.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 157 QFGEMRIFLAVLLGFIVLLSIIFIAIAAGY-----IVRPIRKFTKATQKIASGEYE-IELDVKRKDEIGTLSTSFQKMTK 230
Cdd:PRK10935 141 HFAERKLILLAAISLLGLILILTLVFFTVRftrrqVVAPLNQLVTASQQIEKGQFDhIPLDTTLPNELGLLAKAFNQMSS 220
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
372-457 |
1.80e-06 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 47.96 E-value: 1.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 372 GTIEFFVEELESSVIISISDNGIG-----------------------MEQEEMDR-IFDRfyKVDTARA-RNVEGSGLGL 426
Cdd:cd16916 70 GTITLRAEHQGNQVVIEVSDDGRGidrekirekaierglitadeaatLSDDEVLNlIFAP--GFSTAEQvTDVSGRGVGM 147
|
90 100 110
....*....|....*....|....*....|.
gi 1496527954 427 SIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16916 148 DVVKRSIESLGGTIEVESEPGQGTTFTIRLP 178
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
360-457 |
3.87e-06 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 46.06 E-value: 3.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 360 IFTNSIKFSNDG---GTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRFykvdtararnvEGSGLGLSIVQKIVElh 436
Cdd:COG2172 42 AVTNAVRHAYGGdpdGPVEVELELDPDGLEIEVRDEGPGFDPEDLPDPYSTL-----------AEGGRGLFLIRRLMD-- 108
|
90 100
....*....|....*....|.
gi 1496527954 437 ngNVSVYSTKGeGTTVRVELP 457
Cdd:COG2172 109 --EVEYESDPG-GTTVRLVKR 126
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
213-458 |
8.40e-06 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 48.29 E-value: 8.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 213 KRKDEIGTLSTSFQKMTKSIKELDEMRqefvsnvsHEFQSPLSSIQGFsktLQtekMSEEERnyYLQIIEGESKRMSSLC 292
Cdd:PRK15053 320 RSKDEISTLNAQLTQIKQYVESLRTLR--------HEHLNWMSTLNGL---LQ---MKEYDR--VLEMVQGESQAQQQLI 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 293 KQLLTlasldkeekvlqikEFNlQKQIKDVIFMLEWKWREKDIAVEFdVPDITIQG-----DENLLHQVWSNIFTN---- 363
Cdd:PRK15053 384 DSLRE--------------AFA-DRQVAGLLFGKVQRARELGLKMVI-VPGSQLSQlppglDSTEFAAIVGNLLDNafea 447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 364 SIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEEMDRIFDRfyKVDTaRARNVEGSGLGLSIVQKIVELHNGNVSVY 443
Cdd:PRK15053 448 SLRSDEGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQ--GVST-RADEPGEHGIGLYLIASYVTRCGGVITLE 524
|
250
....*....|....*
gi 1496527954 444 STKGEGTTVRVELPK 458
Cdd:PRK15053 525 DNDPCGTLFSIFIPK 539
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-457 |
6.11e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 41.39 E-value: 6.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 362 TNSIKFSNdGGTIEFFVEELESSVIISISDNGIGmeqeemdrifdrFYKVDTARarnveGSGLGLSIVQKIVELHNGNVS 441
Cdd:cd16917 10 TNALKHAG-ASRVRVTLSYTADELTLTVVDDGVG------------FDGPAPPG-----GGGFGLLGMRERAELLGGTLT 71
|
90
....*....|....*.
gi 1496527954 442 VYSTKGEGTTVRVELP 457
Cdd:cd16917 72 IGSRPGGGTRVTARLP 87
|
|
| HATPase_ETR2_ERS2-EIN4-like |
cd16938 |
Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related ... |
341-456 |
7.43e-05 |
|
Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related domains; This family includes the histidine kinase-like ATPase domains (HATPase) of three out of the five receptors that recognize the plant hormone ethylene in Arabidopsis thaliana. These three proteins have been classified as belonging to subfamily 2: ETR2, ERS2, and EIN4. They lack most of the motifs characteristic of histidine kinases, and EIN4 is the only one in this group containing the conserved histidine that is phosphorylated in two-component and phosphorelay systems. This family also includes the HATPase domains of Escherichia coli RcsD phosphotransferase which is a component of the Rcs-signaling system, a complex multistep phosphorelay involving five proteins, and is involved in many transcriptional networks such as cell division, biofilm formation, and virulence, among others. Also included is Schizosaccharomyces pombe Mak3 (Phk1) which participates in a multi-step two-component related system which regulates H2O2-induced activation of the Sty1 stress-activated protein kinase pathway. Most proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a GAF sensor domain; most are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340415 [Multi-domain] Cd Length: 133 Bit Score: 42.45 E-value: 7.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 341 VPDITIqGDENLLHQVWSNIFTNSIKFSNDGGTIEFFV---------EELESSVIISISDN---------GIGMEQEEMD 402
Cdd:cd16938 1 LPDVVV-GDERRVFQVLLHMLGNLLKMRNGGGNITFRVfleggsedrSDRDWGPWRPSMSDesveirfevEINDSGSPSI 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1496527954 403 RIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVEL 456
Cdd:cd16938 80 ESASMRNSLNRRYNLSELGEHLSFSICKQLVQLMGGNIWIVPGSGLGTTMSLLL 133
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
372-457 |
8.65e-05 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 44.79 E-value: 8.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 372 GTIEFFVEELESSVIISISDNGIGM------------------EQEEMDR------IF-------DrfyKVDtararNVE 420
Cdd:COG0643 309 GTITLSAYHEGGRVVIEVSDDGRGLdlekirakaiekglitaeEAAALSDeellelIFapgfstaE---EVT-----DLS 380
|
90 100 110
....*....|....*....|....*....|....*..
gi 1496527954 421 GSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:COG0643 381 GRGVGMDVVKTNIEALGGTIEIESEPGKGTTFTLRLP 417
|
|
| HATPase_PDK-like |
cd16929 |
Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain ... |
339-457 |
2.53e-04 |
|
Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of all four PDK isoforms (pyruvate dehydrogenase kinases 1-4) that have been described in mammals, and other PDKs including Saccharomyces Pkp1p and Pkp2p. PDKs and phosphatases tightly regulate the mitochondrial pyruvate dehydrogenase complex (PDC) by reversible phosphorylation. PDC catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA, connecting glycolysis and the TCA acid cycle. Also included in this family is mammalian branched-chain alpha-ketoacid dehydrogenase kinase (BDK), a mitochondrial protein kinase that phosphorylates a subunit of the branched-chain a-ketoacid dehydrogenase (BCKD) complex, which catalyzes the oxidative decarboxylation of branched-chain alpha-ketoacids derived from leucine, isoleucine, and valine, a rate-limiting step in the oxidative degradation of these branched-chain amino acids.
Pssm-ID: 340406 [Multi-domain] Cd Length: 169 Bit Score: 41.56 E-value: 2.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 339 FDVPDITIQGDENL--------LHQVWSNIFTNSIKfsndgGTIEFFVEELES-------------SVIISISDNGIGME 397
Cdd:cd16929 22 LSSPELEIEGDPSIrfpyvpshLYYILFELLKNAMR-----ATVESHGDDSDDlppikvtvakgdeDLTIKISDRGGGIP 96
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1496527954 398 QEEMDRIFdrFYKVDTARAR---------------NVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16929 97 REDLARLF--SYMYSTAPQPslddfsdlisgtqpsPLAGFGYGLPMSRLYAEYFGGDLDLQSMEGYGTDVYIYLK 169
|
|
| HATPase_YehU-like |
cd16956 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
351-457 |
1.44e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YehU; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Escherichia coli YehU, a HK of the two-component system (TCS) YehU-YehT which is involved in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase); some have a GAF sensor domain while some have a cupin domain.
Pssm-ID: 340432 [Multi-domain] Cd Length: 101 Bit Score: 38.19 E-value: 1.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 351 NLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESSVIISISDNGIGMEQEemdrifdrfykvDTARARNVEGSGLGLSIV- 429
Cdd:cd16956 4 LTLQPIVENAVKHGLSGLLDGGRVEITARLDGQHLLLEVEDNGGGMDPD------------TLARILIRSSNGLGLNLVd 71
|
90 100 110
....*....|....*....|....*....|
gi 1496527954 430 QKIVEL--HNGNVSVYSTKGEGTTVRVELP 457
Cdd:cd16956 72 KRLRQAfgNDYGLDIECAPGEGTRITIRLP 101
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
226-457 |
3.24e-03 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 39.92 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 226 QKMTKSIKELD---EMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSEEERNYYLQIIEgESKRMSSLCKQLLTLASLD 302
Cdd:PRK10618 434 KKLQQAQREYEknqQARKAFLQNIGDELKQPLQSLAQLAAQLRQTSDEEQQQPELDQLAE-QSDVLVRLVDNIQLLNMLE 512
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 303 KEEKVLQIKEFNLQKQIKDVIFMLEWKWREKD----IAVEFDvPDITIQGDENLLHQVWSNIFTNSIKfSNDGGTIEFFV 378
Cdd:PRK10618 513 TQDWKPEQELFSLQDLIDEVLPEVLPAIKRKGlqllIHNHLK-AEQLRIGDRDALRKILLLLLNYAIT-TTAYGKITLEV 590
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 379 EELESS---VIISISDNGIGMEQEEMDRI---------FDRFYKvdtararnveGSGLGLSIVQKIVELHNGNVSVYSTK 446
Cdd:PRK10618 591 DQDESSpdrLTIRILDTGAGVSIKELDNLhfpflnqtqGDRYGK----------ASGLTFFLCNQLCRKLGGHLTIKSRE 660
|
250
....*....|.
gi 1496527954 447 GEGTTVRVELP 457
Cdd:PRK10618 661 GLGTRYSIHLK 671
|
|
| HATPase_SpoIIAB-like |
cd16942 |
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein ... |
356-452 |
3.49e-03 |
|
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of SpoIIAB, an anti sigma-F factor and a serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli where, early in sporulation, the cell divides into two unequal compartments: a larger mother cell and a smaller forespore. Sigma-F transcription factor is activated in the forespore directly after the asymmetric septum forms, and its spatial and temporal activation is required for sporulation. Free sigma-F can associate with the RNA polymerase core and activate transcription of the sigma-F regulon, its regulation may comprise a partner-switching mechanism involving SpoIIAB, SpoIIAA, and sigma-F as follows: SpoIIAB can form alternative complexes with either: i) sigma-F, holding it in an inactive form and preventing its association with RNA polymerase, or ii) unphosphorylated SpoIIAA and a nucleotide, either ATP or ADP. In the presence of ATP, SpoIIAB acts as a kinase to specifically phosphorylate a serine residue of SpoIIAA; this phosphorylated form has low affinity for SpoIIAB and dissociates, making SpoIIAB available to capture sigma-F. SpoIIAA may then be dephosphorylated by a SpoIIE serine phosphatase and be free to attack the SpoIIAB sigma-F complex to induce the release of sigma-F.
Pssm-ID: 340418 [Multi-domain] Cd Length: 135 Bit Score: 37.52 E-value: 3.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 356 VWSNIFTNSI--KFSNDGGTIEFFVEELESSVI-ISISDNGIGME--QEEMDRIFdrfykvdTARARnVEGSGLGLSIVQ 430
Cdd:cd16942 42 VVSEAVTNAIihGYNNDPNGIVSISVIIEDGVVhLTVRDEGVGIPdiEEARQPLF-------TTKPE-LERSGMGFTIME 113
|
90 100
....*....|....*....|..
gi 1496527954 431 KIVElhngNVSVYSTKGEGTTV 452
Cdd:cd16942 114 NFMD----EVIVESEVNKGTTV 131
|
|
| HATPase_AgrC-ComD-like |
cd16935 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
331-448 |
8.62e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Staphylococcus aureus AgrC which is an HK of the accessory gene regulator (agr) quorum sensing two-component regulatory system (TCS) AgrC-AgrA. The agr system plays a part in the transition from persistent to virulent phenotype. This family also includes Streptococcus pneumoniae ComD HK of the ComD-ComE TCS, involved in quorum sensing and genetic competence.
Pssm-ID: 340412 [Multi-domain] Cd Length: 134 Bit Score: 36.40 E-value: 8.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1496527954 331 REKDIAVEFDVPDITIQGDENL-LHQVWSNIFTNSI----KFSNDGGTIEFFVEELESSVIISISdNGIgmeQEEMDRIF 405
Cdd:cd16935 14 REKGIEFTIEIDIPILLPISPLdLCIIFGNLLDNAIeacaKIDKENRFIHLKIRQKKGFLIISIE-NSY---EGELKKKN 89
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90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1496527954 406 DRFY--KVDTARarnvegsGLGLSIVQKIVELHNGNVSVYSTKGE 448
Cdd:cd16935 90 GLFLstKKDKNH-------GIGLKSIREIVKKYNGNLSIEYENGI 127
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