|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
6-553 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1031.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 6 TPHDVTALPAWQALNDHRKAMQDFSMREAFNADPQRFTQFTLSSCGLFLDYSKNLINAQTRDLLVGLANEVDLKGAIKSL 85
Cdd:PRK00179 1 KNINLTQTPAWQALQAHADEIKDVHLRDLFAADPDRFERFSLTAGGLLLDYSKNRITDETLALLLDLAREAGLEGARDAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 86 FEGEIVNASENRPALHTALRRPVGDKLLVNGVNVMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGP 165
Cdd:PRK00179 81 FAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGSDLGP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 166 ELVSEALLSYAQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAELYRHFI 245
Cdd:PRK00179 161 VMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVAKHFV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 246 AVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNFKELLSGAYSMDQHFQSAPFEQNMPVLLALLG 325
Cdd:PRK00179 241 AVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLLALIG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 326 VWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPA 405
Cdd:PRK00179 321 VWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTKLVPA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 406 DFIVPIVSFNPVSDHHQWLYANCLSQSQALMLGKTRAEAEAELRDKGASEEEVQKLASHKVIPGNRPSNTLVVERISPRR 485
Cdd:PRK00179 401 DFIAPAQPHNPLGDHHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLDRLTPFT 480
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1509092457 486 LGALVALYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLVGSEESPADDASTQGLINYFRGRHR 553
Cdd:PRK00179 481 LGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
11-550 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 708.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 11 TALPAWQalndhrkamqdfSMReafnadpqRFTQFTLSSCGLFLDYSKNLINAQTRDLLVGLANEvdlKGAIKSLFEGEI 90
Cdd:COG0166 2 TQTPAWQ------------HLR--------RFERFSLEAAGLLLDYSKNRITDETLELLLELAEE---EEAREALFAGEK 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 91 VNASENRPALHTALRRPVGdkllvnGVNVMPDVHKVLNQITDLVGRIHDGlwrgyteKPITDVVNIGIGGSFLGPELVSE 170
Cdd:COG0166 59 INPTEGRAVLHGALRLPEA------GEDVMPEVREELARIKAFAEKVRTG-------KRITDVVNIGIGGSDLGPRAVIE 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 171 ALLSYAQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAelYRHFIAVSSN 250
Cdd:COG0166 126 ALKPYFRDGPRVHFVSNVDPDYLAELLAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGEDA--AKHFVAVTDN 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 251 NAAAVAFGIREE-NIFPMWDWVGGRYSLWSAIGLPIALAIGMsNFKELLSGAYSMDQHFQSAPFEQNMPVLLALLGVWYG 329
Cdd:COG0166 204 AGALRAFGIDEGyNTFPFPDWVGGRYSVLSAVGLLPAAAIGI-DFEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYR 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 330 NFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPViwGGVGCNGQHAYHQLLHQGTQLIPADFIV 409
Cdd:COG0166 283 NFKGAETEAVLPYDQRLERFPAWLQQLWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIA 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 410 PIVSFNPVSDhhqWLYANClsQSQALMLGKTRAEAEAelrdkGASEEevqklASHKVIPGNRPSNTLVVERISPRRLGAL 489
Cdd:COG0166 361 VAEPHHDIPD---LLLANL--QGLALLAGKTLDEVLA-----LAAEA-----TPHALFPGNRPSNTILLPKLTPYTLGAL 425
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1509092457 490 VALYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLvGSEESPADDaSTQGLINYFRG 550
Cdd:COG0166 426 IALYEHAVFVQGVLWGINPFDQPGVELGKKLAFALLGKL-GGEEAAAGD-STEALLKRLRA 484
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
55-545 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 651.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 55 DYSKNLINAQTRDLLVGLANEVDLKGAIKSLFEGEIVNASENRPALHTALRRPVGDKLLVNGVNVMPDVHKVLNQITDLV 134
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 135 GRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELVSEALLSYAQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSF 214
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 215 NTLETLKNAQAARAWYLAQGGSEAELYRHFIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNF 294
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 295 KELLSGAYSMDQHFQSAPFEQNMPVLLALLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVST 374
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 375 DTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVPIVSFNP-VSDHHQWLYANCLSQSQALMLGKTRAEAEAELrdkga 453
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNPeNGDHHKILLSNFFAQTEALMVGKSPEEVRKEL----- 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 454 SEEEVQKLASHKVIPGNRPSNTLVVERISPRRLGALVALYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLVGSEE 533
Cdd:pfam00342 396 AAADVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSNK 475
|
490
....*....|..
gi 1509092457 534 SPADDASTQGLI 545
Cdd:pfam00342 476 VSSHDSSTNGLI 487
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
335-524 |
3.17e-71 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 225.17 E-value: 3.17e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 335 QSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVstDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVP---- 410
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGEDY--PTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVkkpq 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 411 --IVSFNPVSDHHQWLYANCLSQSQALMlgktraeaeaelrdkgaseeevqklashkvIPGNRPSNTLVVERISPRRLGA 488
Cdd:cd05016 79 ndVLDYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 1509092457 489 LVALYEHKVFVQSVVWGINAFDQWGVELGKELGKGV 524
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
6-553 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1031.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 6 TPHDVTALPAWQALNDHRKAMQDFSMREAFNADPQRFTQFTLSSCGLFLDYSKNLINAQTRDLLVGLANEVDLKGAIKSL 85
Cdd:PRK00179 1 KNINLTQTPAWQALQAHADEIKDVHLRDLFAADPDRFERFSLTAGGLLLDYSKNRITDETLALLLDLAREAGLEGARDAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 86 FEGEIVNASENRPALHTALRRPVGDKLLVNGVNVMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGP 165
Cdd:PRK00179 81 FAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGSDLGP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 166 ELVSEALLSYAQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAELYRHFI 245
Cdd:PRK00179 161 VMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVAKHFV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 246 AVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNFKELLSGAYSMDQHFQSAPFEQNMPVLLALLG 325
Cdd:PRK00179 241 AVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLLALIG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 326 VWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPA 405
Cdd:PRK00179 321 VWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTKLVPA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 406 DFIVPIVSFNPVSDHHQWLYANCLSQSQALMLGKTRAEAEAELRDKGASEEEVQKLASHKVIPGNRPSNTLVVERISPRR 485
Cdd:PRK00179 401 DFIAPAQPHNPLGDHHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLDRLTPFT 480
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1509092457 486 LGALVALYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLVGSEESPADDASTQGLINYFRGRHR 553
Cdd:PRK00179 481 LGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
11-550 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 708.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 11 TALPAWQalndhrkamqdfSMReafnadpqRFTQFTLSSCGLFLDYSKNLINAQTRDLLVGLANEvdlKGAIKSLFEGEI 90
Cdd:COG0166 2 TQTPAWQ------------HLR--------RFERFSLEAAGLLLDYSKNRITDETLELLLELAEE---EEAREALFAGEK 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 91 VNASENRPALHTALRRPVGdkllvnGVNVMPDVHKVLNQITDLVGRIHDGlwrgyteKPITDVVNIGIGGSFLGPELVSE 170
Cdd:COG0166 59 INPTEGRAVLHGALRLPEA------GEDVMPEVREELARIKAFAEKVRTG-------KRITDVVNIGIGGSDLGPRAVIE 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 171 ALLSYAQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAelYRHFIAVSSN 250
Cdd:COG0166 126 ALKPYFRDGPRVHFVSNVDPDYLAELLAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGEDA--AKHFVAVTDN 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 251 NAAAVAFGIREE-NIFPMWDWVGGRYSLWSAIGLPIALAIGMsNFKELLSGAYSMDQHFQSAPFEQNMPVLLALLGVWYG 329
Cdd:COG0166 204 AGALRAFGIDEGyNTFPFPDWVGGRYSVLSAVGLLPAAAIGI-DFEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYR 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 330 NFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPViwGGVGCNGQHAYHQLLHQGTQLIPADFIV 409
Cdd:COG0166 283 NFKGAETEAVLPYDQRLERFPAWLQQLWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIA 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 410 PIVSFNPVSDhhqWLYANClsQSQALMLGKTRAEAEAelrdkGASEEevqklASHKVIPGNRPSNTLVVERISPRRLGAL 489
Cdd:COG0166 361 VAEPHHDIPD---LLLANL--QGLALLAGKTLDEVLA-----LAAEA-----TPHALFPGNRPSNTILLPKLTPYTLGAL 425
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1509092457 490 VALYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLvGSEESPADDaSTQGLINYFRG 550
Cdd:COG0166 426 IALYEHAVFVQGVLWGINPFDQPGVELGKKLAFALLGKL-GGEEAAAGD-STEALLKRLRA 484
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
55-545 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 651.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 55 DYSKNLINAQTRDLLVGLANEVDLKGAIKSLFEGEIVNASENRPALHTALRRPVGDKLLVNGVNVMPDVHKVLNQITDLV 134
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 135 GRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELVSEALLSYAQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSF 214
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 215 NTLETLKNAQAARAWYLAQGGSEAELYRHFIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNF 294
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 295 KELLSGAYSMDQHFQSAPFEQNMPVLLALLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVST 374
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 375 DTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVPIVSFNP-VSDHHQWLYANCLSQSQALMLGKTRAEAEAELrdkga 453
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNPeNGDHHKILLSNFFAQTEALMVGKSPEEVRKEL----- 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 454 SEEEVQKLASHKVIPGNRPSNTLVVERISPRRLGALVALYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLVGSEE 533
Cdd:pfam00342 396 AAADVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSNK 475
|
490
....*....|..
gi 1509092457 534 SPADDASTQGLI 545
Cdd:pfam00342 476 VSSHDSSTNGLI 487
|
|
| PLN02649 |
PLN02649 |
glucose-6-phosphate isomerase |
9-548 |
0e+00 |
|
glucose-6-phosphate isomerase
Pssm-ID: 215351 [Multi-domain] Cd Length: 560 Bit Score: 583.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 9 DVTALPAWQALNDHRKAMQDFSMREAFNaDPQRFTQFTLSSCGLFLDYSKNLINAQTRDLLVGLANEVDLKGAIKSLFEG 88
Cdd:PLN02649 7 LISDTPAWKRLVAHVYQIKKTHLRELLN-DAERCQSMIAEFDGIYLDYSRQRVTDETMELLFPLAEAANLFEKIEAMFSG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 89 EIVNASENRPALHTALRRPVGDKLLVNGVNVMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELV 168
Cdd:PLN02649 86 EIINSTEDRAVLHVALRAPRLAPILVDGKNVVPEVWEVLDKIKAFSEDVRSGKWKGATGKRFTNVVSIGIGGSFLGPLFV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 169 SEALLSY-----AQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAeLYRH 243
Cdd:PLN02649 166 HEALATDpealkSAKGRKLRFLANVDPVDIARQIAQLDPETTLVVVVSKTFTTAETMLNARTVRKWLRDALGGLA-VAKH 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 244 FIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIG-LPIALAIGMSNFKELLSGAYSMDQHFQSAPFEQNMPVLLA 322
Cdd:PLN02649 245 MVAVSTNLLLVNKFGIDPWNAFPFWDWVGGRYSVCSAVGlLPLSLQYGFDVVEEFLEGAASMDEHFRTAPLKENIPVLLG 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 323 LLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYHQLLHQGtQL 402
Cdd:PLN02649 325 LLSVWNSSFLGYPARAILPYSQALLKFAPHIQQLDMESNGKGVDLDGNPLPVNTGEIDFGEPGTNGQHSFYQLIHQG-RN 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 403 IPADFIVPIVSFNPVSD-------HHQWLYANCLSQSQALMLGKTRAEAEAelrdkgasEEEVQKLASHKVIPGNRPSNT 475
Cdd:PLN02649 404 IPCDFIGVVRSQQPVHLwlgegvsNHDELMSNFFAQPDALAYGKTPEQLRA--------EGVPEELIPHKVFAGNRPSLS 475
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1509092457 476 LVVERISPRRLGALVALYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLVGS--EESPAD--DASTQGLINYF 548
Cdd:PLN02649 476 ILLPELTAYTVGQLLALYEHRVAVQGFIWNINSFDQWGVELGKALAKRVRAVLNEArtKGEPVEgfNSSTTALLNHY 552
|
|
| PTZ00430 |
PTZ00430 |
glucose-6-phosphate isomerase; Provisional |
9-549 |
0e+00 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 185612 Cd Length: 552 Bit Score: 547.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 9 DVTALPAWQALNDHRKAMQDFSMREAFNaDPQRFTQFTLSSCGLFLDYSKNLINAQTRDLLVGLANEVDLKGAIKSLFEG 88
Cdd:PTZ00430 2 DLESLKSYKNLLSLAEKLKKVHLRDLLK-DEERNKSLIKEFKGVTLDLSRQRLDEETLKLLIELAEEAKLKEKIKDMFNG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 89 EIVNASENRPALHTALRRPVGDKLLVNGVNVMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELV 168
Cdd:PTZ00430 81 EKINTTENRAVLHTALRAPRGEKVVVDGKNVLEDVHEVLDRIKKFSDKIRSGEILGSTGKKLKNVICIGIGGSYLGTEFV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 169 SEALLSY-----AQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAELYRH 243
Cdd:PTZ00430 161 YEALRTYgeareASKGRKLRFLANVDPIDVRRATEGLDPEETLVVIISKTFTTAETMLNAKTVRQWLLDNIKSKEALSKH 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 244 FIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIG-LPIALAIGMSNFKELLSGAYSMDQHFQSAPFEQNMPVLLA 322
Cdd:PTZ00430 241 LCAVSTNLKLTSEFGIPDENVFGFWDWVGGRFSVTSAVGiLPLSIQFGYDIVQQFLNGCHDMDEHFRTAPLEENLPVLLG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 323 LLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYHQLLHQGtQL 402
Cdd:PTZ00430 321 LTSFYNSTFLGYNCVAILPYCQALLKFPAHVQQLLMESNGKSVTLDGNTLDYNTGEIYFGEPGTNGQHSFYQLLHQG-RV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 403 IPADFI------VPIVSFNPVSDHHQWLYANCLSQSQALMLGKTRAEAEAElrdkGASEEevqkLASHKVIPGNRPSNTL 476
Cdd:PTZ00430 400 VPSEFIgfaksqNPIKLLGEPVSNHDELMSNFFAQPDALAFGKTYEELEKE----GVPEE----LIPHKVFPGNRPSLLL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 477 VVERISPRRLGALVALYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRL-VGSEESPADDA------STQGLINYFR 549
Cdd:PTZ00430 472 LFPELNPYTIGQLLALYEHRTVVEGFLWNINSFDQWGVELGKVLAKDVRNLFkDNRSNSSPHAKeskfngSTKRLLSYYL 551
|
|
| pgi |
PRK14095 |
glucose-6-phosphate isomerase; Provisional |
1-548 |
1.01e-132 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237608 Cd Length: 533 Bit Score: 397.08 E-value: 1.01e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 1 MAYYRtphDVTALPAWQALNDHRKAMQDFSMREAFNADpqRFTQFTLSSCGLFLDYSKNLINAQTRDLLVGLANEVDLKG 80
Cdd:PRK14095 1 MMNYK---NFLDLESFKILQELAPEPLDLTLPGVLSEE--RIKKYSLSGEGFTYNYATERVDDRILAALQNLADEAELIE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 81 AIKSLFEGEIVN-----ASENRPALHTALRRPVGDKLLV-NGVNVMPDVHKVLNQITDLVGRIHDGLWRGYTEKPITDVV 154
Cdd:PRK14095 76 KMKAMQNGAVINriegfPSENRPVLHTATRGQVGDSVLTdEAEDMAEFSKRELERLAEFLKKVRSGEIKNSNGKKFTTVV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 155 NIGIGGSFLGPELVSEALLSYAQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQG 234
Cdd:PRK14095 156 QIGIGGSDLGPKALYLALKNYAKKDKRVHFISNVDPDDAAEVLSEIDLAKTLFIVVSKSGTTLETAANEEFVRDALKKAG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 235 GSEAelyRHFIAVSSNNAAaVAFGIREENIFPMWDWVGGRYSLWSAIGLP-IALAIGMSNFKELLSGAYSMDQHFQSAPF 313
Cdd:PRK14095 236 LDYK---KHFIAVTSEGSP-MDDESGYLEVFHMWDSIGGRFSSTSMVGGVvLGFAFGFEVFKEFLKGAAAMDKAALNPNI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 314 EQNMPVLLALLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYH 393
Cdd:PRK14095 312 RENLPLLAALIGIWNRNFLGYPTTAVIPYSQALERFPAHLQQLDMESNGKSVNRFGEPINFKTGPIIWGEPGTNGQHSFF 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 394 QLLHQGTQLIPADFI--------VPIVSFNPVSdhHQWLYANCLSQSQALMLGKTRAEAeaelrdkgaseeevqklasHK 465
Cdd:PRK14095 392 QLLHQGTDIVPVEFIgfkesqlgQDIVIQGSTS--QQKLFANLIAQIIALACGKENTNP-------------------NK 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 466 VIPGNRPSNTLVVERISPRRLGALVALYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLVGseESPADDASTQGLI 545
Cdd:PRK14095 451 NFKGNRPSSLLVAKQLTPYTLGALLAHYENKVMFQGFCWNINSFDQEGVQLGKVLANQILGIMKG--EAPGEFPEADGLL 528
|
...
gi 1509092457 546 NYF 548
Cdd:PRK14095 529 KLF 531
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
335-524 |
3.17e-71 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 225.17 E-value: 3.17e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 335 QSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVstDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVP---- 410
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGEDY--PTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVkkpq 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 411 --IVSFNPVSDHHQWLYANCLSQSQALMlgktraeaeaelrdkgaseeevqklashkvIPGNRPSNTLVVERISPRRLGA 488
Cdd:cd05016 79 ndVLDYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 1509092457 489 LVALYEHKVFVQSVVWGINAFDQWGVELGKELGKGV 524
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| SIS_PGI_1 |
cd05015 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
124-288 |
1.12e-67 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240146 Cd Length: 158 Bit Score: 215.85 E-value: 1.12e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 124 HKVLNQITDLVGRIHDGlwrgyteKPITDVVNIGIGGSFLGPELVSEALLSYAQKGVRCHYLANIDGSEFHELTMKLRAE 203
Cdd:cd05015 1 RAELERIKEFAEKVRSG-------KKITDVVVIGIGGSDLGPRAVYEALKPYFKGGLRLHFVSNVDPDDLAELLKKLDPE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 204 TTLFIVSSKSFNTLETLKNAQAARAWYLAQGGseAELYRHFIAVSSNNAAAVA-FGIREENIFPMWDWVGGRYS-LWSAI 281
Cdd:cd05015 74 TTLFIVISKSGTTLETLANARLAREWLEEAGG--DDLAKHFVAITDNGSGLLKkAGIEGLNTFEIPDWVGGRFSvLSSVG 151
|
....*..
gi 1509092457 282 GLPIALA 288
Cdd:cd05015 152 GLPLALA 158
|
|
| pgi |
PRK14096 |
glucose-6-phosphate isomerase; Provisional |
81-518 |
1.22e-58 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237609 [Multi-domain] Cd Length: 528 Bit Score: 203.58 E-value: 1.22e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 81 AIKSLFEGEIVNASENRPALHTALRRPvgdkllvngvNVMPD------VHKVLNQITDLVGRIHDGLWRGYTEKPITDVV 154
Cdd:PRK14096 49 AMAALEAGAIANPDEGRMVGHYWLRNP----------ELAPTpeiraeITETLAQIEAFAAKVHSGTIKPPNGEKFTDVL 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 155 NIGIGGSFLGPELVSEALLSyAQKGVRCHYLANID----GSEFHELTMKLRaeTTLFIVSSKSFNTLETLKNAQAARAWY 230
Cdd:PRK14096 119 WIGIGGSALGPQFVAEALQP-NSDGLNIHFIDNTDpdgiDRVLAELGDRLA--TTLVVVISKSGGTPETRNGMLEAKAAY 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 231 LAQGGSEAelyRHFIAVSSNNA--AAVAfgiREEN---IFPMWDWVGGRYSLWSAIGL-PIALaIGmSNFKELLSGAYSM 304
Cdd:PRK14096 196 EAAGLDFA---SHAVAITMKGSklDQLA---QSEGwlaRFPMWDWVGGRTSETSAVGLlPAAL-QG-IDIRAFLAGAKQM 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 305 DQHFQSAPFEQNMPVLLALlgVWY--GNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVstDTGPVIWG 382
Cdd:PRK14096 268 DEATRVPDLKNNPAALLAL--AWYyaGDGKGKKDMVVLPYKDRLLLFSRYLQQLVMESLGKELDLDGNVV--HQGIAVYG 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 383 GVGCNGQHAYHQLLHQGtqlIPADFivpiVSFNPVsdhhqwlyanclsqsqalmlgktraeaeaeLRDKGASEEEVQKla 462
Cdd:PRK14096 344 NKGSTDQHAYVQQLRDG---VDNFF----VTFIEV------------------------------LEDRQGSSIEVEP-- 384
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1509092457 463 shKVIPG-----------------NRPSNTLVVERISPRRLGALVALYEHKV-FVQSVVwGINAFDQWGVELGK 518
Cdd:PRK14096 385 --GVTSGdylsgflqgtrqalyenGRQSITITIPEVNPRTLGALIALFERAVgLYASLV-NINAYHQPGVEAGK 455
|
|
| PRK00973 |
PRK00973 |
glucose-6-phosphate isomerase; Provisional |
151-518 |
2.67e-30 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 179193 [Multi-domain] Cd Length: 446 Bit Score: 123.56 E-value: 2.67e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 151 TDVVNIGIGGSFLGPELVSEALL--------SYAQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKN 222
Cdd:PRK00973 72 DNVVVLGIGGSALGNLALHYALNplnwnelsKEERNGPRVFVLDNVDPEKTASILDVIDLEKTLFNVISKSGNTAETLAN 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 223 AQAARAWYLAQGGSEAElyrHFIAVSSNNAAAVAFGIREENI--FPMWDWVGGRYSLWSAIGLPIALAIGMsNFKELLSG 300
Cdd:PRK00973 152 YLIIRGILEKLGLDPKK---HLVFTTDPEKGKLKKIAEKEGYrtLEIPENVGGRFSVLTPVGLAPAAALGI-DIEELLEG 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 301 AYSMDQHFQSAPFEQNMPVLLALLGVWYGNFwGAQSHAILPYDHYLRNITKHLQQLDMESNGKsvRQDG-TPVstdtgpv 379
Cdd:PRK00973 228 AKEMDKICEKEDIFKNPALLNALIHYLYYNR-GKNISVMMPYSERLKYFGDWYRQLWAESLGK--KGVGqTPV------- 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 380 iwGGVGCNGQHAYHQLLHQGtqliPADFIVPIVSFNP-------VSDHHQWLYANCLSqsqalmlGKTRAEA-EAELRdk 451
Cdd:PRK00973 298 --KALGATDQHSQLQLYMEG----PKDKIITFLKVEKyrrdveiPYEYEDIEELSYLG-------GHKLSELiNSEQK-- 362
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1509092457 452 gASEEEVQKlashkvipGNRPSNTLVVERISPRRLGALVALYEHKVFVQSVVWGINAFDQWGVELGK 518
Cdd:PRK00973 363 -GTEIALTE--------NGRPNVKITLDELNEYTVGQLFYMYEMQTAFMGELLNINAFDQPGVELGK 420
|
|
| PRK03868 |
PRK03868 |
glucose-6-phosphate isomerase; Provisional |
150-518 |
3.29e-26 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 235168 Cd Length: 410 Bit Score: 110.79 E-value: 3.29e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 150 ITDVVNIGIGGSFLGPELVSEALLSYAQKGVRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETLKNAQAARAW 229
Cdd:PRK03868 58 IKNIVVIGIGGSSLGVKAIYSFLKNEKNNKKELHFLENTDPISINKTLSKINLENTLFIVISKSGTTIETISIFKYLLSH 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 230 YlaqgGSEAELYRHFIAV----SSNNAAAVAFGIREENIFPMwdwVGGRYSLWSAIGLpIALAIGMSNFKELLSGAYSMD 305
Cdd:PRK03868 138 F----KLDQELKKNFLFItdpdSKLEQFAKENNIKCFNIPKN---VGGRFSVLSAVGI-VPLALCGYDIKALLEGAKACK 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 306 QHFqsapFEQNMPVLL--ALlgvWYGNFWGAQS-HAILPYDHYLRNITKHLQQLDMESNGK----SVRQDGTPVstdtgp 378
Cdd:PRK03868 210 DSF----FEQKEDHILkkAY---FYATHKNAYNiNVLFSYSDALKGFNDWYVQLWGESLGKkqgyKTRVGLTPI------ 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 379 viwGGVGCNGQHAYHQLLHQGTQ------LIPADF----IVPIVSFNPVSDHHqwlYANCLSQSQALmlgktRAEAEAEL 448
Cdd:PRK03868 277 ---GLIGSRDQHSFLQLIMEGPRdktvtfIKIKDFqnapKIPNISLKGLESLD---FVNGVSFNELI-----NAQCDATM 345
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1509092457 449 rdkgaseeevqklasHKVIPGNRPSNTLVVERISPRRLGALVALYEhkvFVQSVV---WGINAFDQWGVELGK 518
Cdd:PRK03868 346 ---------------EALIAEDIPVDVITLEKLDEFSIGYLIYYYE---LLTSAVgkmLGINTYDQPGVEVGK 400
|
|
| PRK09533 |
PRK09533 |
bifunctional transaldolase/phosoglucose isomerase; Validated |
150-326 |
6.52e-16 |
|
bifunctional transaldolase/phosoglucose isomerase; Validated
Pssm-ID: 236551 [Multi-domain] Cd Length: 948 Bit Score: 81.17 E-value: 6.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 150 ITDVVNIGIGGSFLGPELVSEallSYAQKG--VRCHYLANIDGSEFHELTMKLRAETTLFIVSSKSFNTLETlkNAQAAR 227
Cdd:PRK09533 455 FTDAVVLGMGGSSLGPEVLAE---TFGQRDgfPKLHVLDSTDPAQVRALEAAVDLARTLFIVSSKSGGTLEP--NIFKDY 529
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 228 AWYLAQGGSEAELYRHFIAV----SSNNAAAVAFGIREenIFPMWDWVGGRYSLWSAIGLPIALAIGMsNFKELLSGAYS 303
Cdd:PRK09533 530 FFARVKEVLGAKAGRHFVAVtdpgSSLEKVAKEDGFRK--IFHGDPDIGGRYSVLSPFGLVPAAAAGI-DVRALLDSALA 606
|
170 180
....*....|....*....|....*
gi 1509092457 304 M-DQHFQSAPFEQNMPVLLAL-LGV 326
Cdd:PRK09533 607 MvRSCGPSVPPADNPGVQLGLaLGV 631
|
|
| pgi |
PRK14097 |
glucose-6-phosphate isomerase; Provisional |
151-316 |
3.55e-09 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 184504 Cd Length: 448 Bit Score: 59.08 E-value: 3.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 151 TDVVNIGIGGSFLGPELVSEALLS--------YAQKGVRCHYLAN-IDGSEFHELTMKLRAETTLFIVSSKSFNTLETLK 221
Cdd:PRK14097 74 DVLVVIGIGGSYLGARAAIEFLNHsfynllpkEQRKAPQIIFAGNsISSTYLADLLEYLKDKDFSINVISKSGTTTEPAI 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509092457 222 NAQAARAWYLAQGGseAELYRHFIAVSSNNAAAVAFGIREEN---IFPMWDWVGGRYSLWSAIGL-PIALAiGMsNFKEL 297
Cdd:PRK14097 154 AFRIFKELLEKKYG--KEEAKKRIYATTDKAKGALKTLADAEgyeTFVIPDDVGGRFSVLTAVGLlPIAVA-GI-DIDAL 229
|
170
....*....|....*....
gi 1509092457 298 LSGAYSMDQHFQSAPFEQN 316
Cdd:PRK14097 230 MKGAADARKDYSSSDLSEN 248
|
|
| SIS_PGI_PMI_1 |
cd05017 |
The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the ... |
152-227 |
1.09e-03 |
|
The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the phosphoglucose isomerase (PGI) and the phosphomannose isomerase (PMI) functions. These functions catalyze the reversible reactions of glucose 6-phosphate to fructose 6-phosphate, and mannose 6-phosphate to fructose 6-phosphate, respectively at an equal rate. This protein contains two SIS domains. This alignment is based on the first SIS domain.
Pssm-ID: 240148 [Multi-domain] Cd Length: 119 Bit Score: 39.17 E-value: 1.09e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1509092457 152 DVVNIGIGGSFLGPELVSEALLSYAQKGVRCHYLANIDGSefheltmklRAETTLFIVSSKSFNTLETLKNAQAAR 227
Cdd:cd05017 1 NIVILGMGGSGIGGDLLESLLLDEAKIPVYVVKDYTLPAF---------VDRKTLVIAVSYSGNTEETLSAVEQAK 67
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