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Conserved domains on  [gi|1511333616|ref|WP_123039393|]
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sugar ABC transporter permease [Cohnella candidum]

Protein Classification

ABC transporter permease( domain architecture ID 10008345)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0055085|GO:0140359|GO:0042626|GO:0016020
PubMed:  31571164|27273632|26517919|18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 4-306 3.39e-136

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 387.91  E-value: 3.39e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616   4 QGFWGDVRKYRTLLLMLTPAVLFFILFAYVPMAGIVLAFKQFNYDGGIFGSPWNGFDNFRFFFDSGNAWMVTRNTALYNI 83
Cdd:COG4209    17 KSFLKRLKRDWQLYLMLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLISL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  84 AFILVNNLLQIFAAILLFEVAGKWFRKITQTVLFLPYFISWVVVGAIAYNLFNYDVGTVNAVLKAVGMEPIDIYNTAAYW 163
Cdd:COG4209    97 LKLVFGFPLPIILALLLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDTGLVNQLLRALGGEPINFLTEPKYF 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 164 PVILVAVAAWKTLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLAVGNIFRGDFGMYYNM 243
Cdd:COG4209   177 RPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIGNILNVGFEQIYLL 256

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1511333616 244 vgNNGLLFSSTDVIDTFVFRSLTTSNEIGMSAAAGFYQSVLGFATIMLANYAVRKYDkERALF 306
Cdd:COG4209   257 --YNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLG-EESLF 316
 
Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 4-306 3.39e-136

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 387.91  E-value: 3.39e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616   4 QGFWGDVRKYRTLLLMLTPAVLFFILFAYVPMAGIVLAFKQFNYDGGIFGSPWNGFDNFRFFFDSGNAWMVTRNTALYNI 83
Cdd:COG4209    17 KSFLKRLKRDWQLYLMLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLISL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  84 AFILVNNLLQIFAAILLFEVAGKWFRKITQTVLFLPYFISWVVVGAIAYNLFNYDVGTVNAVLKAVGMEPIDIYNTAAYW 163
Cdd:COG4209    97 LKLVFGFPLPIILALLLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDTGLVNQLLRALGGEPINFLTEPKYF 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 164 PVILVAVAAWKTLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLAVGNIFRGDFGMYYNM 243
Cdd:COG4209   177 RPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIGNILNVGFEQIYLL 256

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1511333616 244 vgNNGLLFSSTDVIDTFVFRSLTTSNEIGMSAAAGFYQSVLGFATIMLANYAVRKYDkERALF 306
Cdd:COG4209   257 --YNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLG-EESLF 316
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
18-233 1.51e-08

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 54.83  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  18 LMLTPAVLFFILFAYVPmAGIVLAFKQFNYDGGIFGSPWNGFDNF-RFFFDS---GNAWMVTRNTALYNIAFILVNNLlq 93
Cdd:PRK10561    1 LLVAPQLIITVIFFIWP-AGEALWYSLQSVDPFGFSSQFVGLDNFvALFHDSyylDSFWTTIKFSTLVTVSGLLVSLF-- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  94 iFAAILLFEVAGkwfRKITQTVLFLPYFISWVVVGAIAYNLFNYDVGTVNAVLKAVGMEPIDIYNTA-AYWPVILVAVaa 172
Cdd:PRK10561   78 -FAALVDYVVRG---SRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGqAMFLVVFASV-- 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1511333616 173 WKTLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPtvIILFLLAVGNIF 233
Cdd:PRK10561  152 WKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAP--VSFFLLVVNLVY 210
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 93-235 3.70e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.52  E-value: 3.70e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  93 QIFAAILLFEVAGKWFRKITQTVLFLPYFISWVVVGAIAYNLFNYDVgtvnavlkavgmepidiyntAAYWPVILVAVAA 172
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI--------------------LGHGILPAIILAL 60

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1511333616 173 WKTLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLAVGNIFRG 235
Cdd:pfam00528  61 LGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGG 123
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 76-235 4.12e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 43.42  E-value: 4.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  76 RNTALYNIAFILVNNLLQIFAAILLFEVaGKWFRKITQTVLFLPYFISWVVVGAIAYnlfnydvgtvnAVLKAVGMEPID 155
Cdd:cd06261     2 LNTLLLALIATLLALVLGLLLGIILARK-RGKLDRLLRRIIDLLLSLPSLVLGLLLV-----------LLFGVLLGWGIL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 156 IYNTaayWPVILVAVAAWktLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLAVGNIFRG 235
Cdd:cd06261    70 PGLG---LPALILALLLI--APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGE 144
 
Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 4-306 3.39e-136

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 387.91  E-value: 3.39e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616   4 QGFWGDVRKYRTLLLMLTPAVLFFILFAYVPMAGIVLAFKQFNYDGGIFGSPWNGFDNFRFFFDSGNAWMVTRNTALYNI 83
Cdd:COG4209    17 KSFLKRLKRDWQLYLMLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLISL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  84 AFILVNNLLQIFAAILLFEVAGKWFRKITQTVLFLPYFISWVVVGAIAYNLFNYDVGTVNAVLKAVGMEPIDIYNTAAYW 163
Cdd:COG4209    97 LKLVFGFPLPIILALLLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDTGLVNQLLRALGGEPINFLTEPKYF 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 164 PVILVAVAAWKTLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLAVGNIFRGDFGMYYNM 243
Cdd:COG4209   177 RPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIGNILNVGFEQIYLL 256

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1511333616 244 vgNNGLLFSSTDVIDTFVFRSLTTSNEIGMSAAAGFYQSVLGFATIMLANYAVRKYDkERALF 306
Cdd:COG4209   257 --YNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLG-EESLF 316
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
11-298 3.44e-52

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 173.01  E-value: 3.44e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  11 RKYRTLLLMLTPAVLFFILFAYVPMA-GIVLAFkqFNYDGGIFGSPWNGFDNFRFFFDSGNAWMVTRNTALYNIAFILVN 89
Cdd:COG1175    15 RRRLAAYLFLLPALLLLLVFVLYPLLyTLYLSF--TDWNLLGPPPEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVPLQ 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  90 NLLQIFAAILLFEvaGKWFRKITQTVLFLPYFISWVVVGAIAYNLFNYDVGTVNAVLKAVGMEPIDIYNTAAYWPVILVA 169
Cdd:COG1175    93 LVLGLLLALLLNR--KLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAVII 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 170 VAAWKTLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLAVGNIFRgDFGMYYNMvgNNGL 249
Cdd:COG1175   171 VTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQ-VFDLVYVL--TGGG 247

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1511333616 250 LFSSTDVIDTFVFRSLTTSNEIGMSAAAGFYQSVLGFATIMLANYAVRK 298
Cdd:COG1175   248 PGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRR 296
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 10-298 7.86e-16

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 75.95  E-value: 7.86e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  10 VRKYRTLLLMLTPAVLFFILFAYVPMAGIV-LAFKQFNYDGGIFGSPwnGFDNFRFFFDSGNAWMVTRNTALYNIAFILV 88
Cdd:COG1176     5 LRRRLRPLLLLLPALLWLLLFFVLPLLLLLvYSFTTRDPYGGVVPGF--TLENYARLFTDPLYLKVLLRTLWIALLTTLI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  89 NNLLQIFAAILLFEVAGKWfRKITQTVLFLPYFISwVVVGAIAYNLFNYDVGTVNAVLKAVGM--EPIDIYNTaaYWPVI 166
Cdd:COG1176    83 CLLLGYPIAYFLARAPPRW-RNLLLLLVILPFWTS-FLVRTYAWIVLLGRNGLLNSLLLALGLidEPLRLLYT--EFAVV 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 167 LVAVaaWKTLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLavgnIFRGDFGMYYN---M 243
Cdd:COG1176   159 IGLV--YVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLL----VFIPALGAFVTpalL 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1511333616 244 VGNNGLLFSstdvidTFVFRSLTTSNEIGMSAAAGFYQSVLGFATIMLANYAVRK 298
Cdd:COG1176   233 GGGKVLMIG------NLIYQQFLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRR 281
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
11-298 1.60e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 64.41  E-value: 1.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  11 RKYRTLLLMLTPAVLFFILFAYVPMAGIVLAfkqfnydggifgSPWNGFDNFRFFFDSGNAWMVTRNTALYNIAFILVNN 90
Cdd:COG1178     4 RPRRRPRLLLLLLALLLALLVLLPLLALLLR------------AFTDGLANFWALLSDPYLWRALGNTLLLALLVTLLSL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  91 LLQIFAAILL--FEVAGkwfRKITQTVLFLPYFISwVVVGAIAY-NLFNYDvGTVNAVLKAV-GMEPIDIYNtaaYWPVI 166
Cdd:COG1178    72 LLGVPLAWLLarTDFPG---RRLLRWLLLLPLALP-PYVVALAWiALFGPN-GLLNTLLRALfGLEPPDIYG---LGGII 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 167 LVAVAAwkTLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLAVGNIFrGDFGMYYnMVGN 246
Cdd:COG1178   144 LVLVLF--NYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCL-ADFGTPL-VLGG 219

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1511333616 247 NgllfssTDVIDTFVFRSLTTSNEIGMSAAAGFYQSVLGFATIMLANYAVRK 298
Cdd:COG1178   220 G------YTTLTTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRR 265
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 24-228 3.96e-10

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 59.35  E-value: 3.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  24 VLFFILFAYVPMAGIVLAfkQFNyDGGIFGSPWNGF--DNFRFFFDSGNAWMVTRNTALynIAFI--LVNNLLQIFAAIL 99
Cdd:COG1177    13 LALVLLFLYLPILVLVLY--SFN-DSWFLTFPPEGFtlRWYAELFSDPRLLDALLNSLL--IALLstLLATVLGTPAALA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 100 LFEVAGKWfRKITQTVLFLPYFISWVVVGAIAYNLFNydvgtvnavlkavgmePIDIYNTaaYWPVILVAVAawKTLGYG 179
Cdd:COG1177    88 LARYRFRG-RRLLLALLLLPLVVPGIVLGVALLLLFS----------------ALGLSGG--LWGLILAHVV--FTLPFV 146

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1511333616 180 TVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLA 228
Cdd:COG1177   147 VLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLA 195
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
18-233 1.51e-08

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 54.83  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  18 LMLTPAVLFFILFAYVPmAGIVLAFKQFNYDGGIFGSPWNGFDNF-RFFFDS---GNAWMVTRNTALYNIAFILVNNLlq 93
Cdd:PRK10561    1 LLVAPQLIITVIFFIWP-AGEALWYSLQSVDPFGFSSQFVGLDNFvALFHDSyylDSFWTTIKFSTLVTVSGLLVSLF-- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  94 iFAAILLFEVAGkwfRKITQTVLFLPYFISWVVVGAIAYNLFNYDVGTVNAVLKAVGMEPIDIYNTA-AYWPVILVAVaa 172
Cdd:PRK10561   78 -FAALVDYVVRG---SRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGqAMFLVVFASV-- 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1511333616 173 WKTLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPtvIILFLLAVGNIF 233
Cdd:PRK10561  152 WKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAP--VSFFLLVVNLVY 210
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 23-228 1.92e-07

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 51.25  E-value: 1.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  23 AVLFFILFAYVPMAGIVL-AFKQ----FNYDGGIFGSPWNgFDNFRFFFDSGNAWMVTRNTALYNIAFILVNNLLQIFAA 97
Cdd:COG0395    20 LLILLALLFLFPLYWMVVtSFKPpaeiFSGPPSLLPSEFT-LENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLAA 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  98 ILL--FEVAGkwfRKITQTVLFLPYFISwVVVGAIA-YNLFNYdvgtvnavlkavgmepIDIYNTaaYWPVILVAVAAwk 174
Cdd:COG0395    99 YALarFRFRG---RKLLFLLILATLMIP-GQVLLIPlYLLFRQ----------------LGLLNT--YWGLILPYLAF-- 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1511333616 175 TLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLA 228
Cdd:COG0395   155 GLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFT 208
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
23-298 3.01e-07

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 51.32  E-value: 3.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  23 AVLFFILFAYVPMAGIVLAFKQFNYDGGIfgspwnGFDNFRFFFDSGNAWMVTRNTALYNI--AFILVnnllqIFAAILL 100
Cdd:COG1178   294 CLLLVLLGLLLPLLALLLWSLTKALDDNL------TLDNYRFVLLDPSLLRALLNSLLLALlaALLAV-----LLALLLA 362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 101 FEVA--GKWFRKITQTVLFLPYFISWVVVGaIAYNLFnydvgtvnavlkAVGMEPIDIYNTAAywpvILVAVAAWKTLGY 178
Cdd:COG1178   363 YLVRrrRGRLARLLDRLAMLPYAVPGIVLG-LGLLLL------------FNRPLPLLLYGTLA----ILVLAYVVRFLPF 425

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 179 GTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLAVGNIFrGDFGMyynmvgnnGLLFSS--TDV 256
Cdd:COG1178   426 ALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSM-KELSA--------TLLLRPpgFET 496

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1511333616 257 IDTFVFRsLTTSNEIGMSAAAGFYQSVLGFATIMLANYAVRK 298
Cdd:COG1178   497 LAVLIYQ-LASSGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
malF PRK10999
maltose ABC transporter permease MalF;
109-219 8.82e-07

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 49.96  E-value: 8.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 109 RKITQTVLFLPY----FISWVVVGAiaynLFNYDVGTVNAVLKAV-GMEPiDIYNTAAYWPVILVAVAAWktLGYGTVMY 183
Cdd:PRK10999  320 KAVYRVLLILPYavpsFISILIFKG----LFNQSFGEINMMLSALfGIKP-AWFSDPTLAKTMILIVNTW--LGYPYMMI 392

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1511333616 184 LAA--ITSIDTEMYEAAEIDGANVFQRIMRITVPNLFP 219
Cdd:PRK10999  393 LCMglLKAIPDDLYEASAMDGAGPFQNFFKITLPLLIK 430
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 93-235 3.70e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.52  E-value: 3.70e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  93 QIFAAILLFEVAGKWFRKITQTVLFLPYFISWVVVGAIAYNLFNYDVgtvnavlkavgmepidiyntAAYWPVILVAVAA 172
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI--------------------LGHGILPAIILAL 60

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1511333616 173 WKTLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLAVGNIFRG 235
Cdd:pfam00528  61 LGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGG 123
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 76-235 4.12e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 43.42  E-value: 4.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  76 RNTALYNIAFILVNNLLQIFAAILLFEVaGKWFRKITQTVLFLPYFISWVVVGAIAYnlfnydvgtvnAVLKAVGMEPID 155
Cdd:cd06261     2 LNTLLLALIATLLALVLGLLLGIILARK-RGKLDRLLRRIIDLLLSLPSLVLGLLLV-----------LLFGVLLGWGIL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616 156 IYNTaayWPVILVAVAAWktLGYGTVMYLAAITSIDTEMYEAAEIDGANVFQRIMRITVPNLFPTVIILFLLAVGNIFRG 235
Cdd:cd06261    70 PGLG---LPALILALLLI--APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGE 144
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 11-229 2.47e-03

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 38.83  E-value: 2.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  11 RKYRTLLLMLTPAVLFFILFAYvPMAGIVLAfkqfnydgGIFGSPWNGFDNFRFFFDSGnawmVTRnTALYNIAFILVNN 90
Cdd:PRK15050   20 RRLRPLLWLLLPLLVLAPLVVY-PLVRVVLQ--------SLTGEHGLGLATYRAVLGSP----DFR-GALLTTLQIAFAS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1511333616  91 -----LLQIFAAILLFEV---AGKWFRKITQTVLFLPYFIswvvvgaIAYNL-FNY-DVGTVNAVLKAV---GMEPIDIY 157
Cdd:PRK15050   86 tagclVLGVLLALVLAFVpfpGASLVGRFIDTFVAFPSFL-------ITLAFtFLYgSAGSVNIALQRLfglEAPPLDFL 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1511333616 158 NTAayWPVILVAVAAWKTLgygtVM--YLAAITSIDTEMYEAAEIDGAN----VFQRIMRITVPNLFPTVIILFLLAV 229
Cdd:PRK15050  159 YSP--GGVILAEITFYTPF----VVrpLLAAFAQLDARQLEAAASLGASpwrvARRVILPEAWPALAAGGSLCLLLTL 230
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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