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Conserved domains on  [gi|1518538986|ref|WP_123396437|]
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MULTISPECIES: 50S ribosomal protein L11 methyltransferase [unclassified Muribaculum]

Protein Classification

50S ribosomal protein L11 methyltransferase( domain architecture ID 11455142)

50S ribosomal protein L11 methyltransferase is a class I SAM-dependent methyltransferase that methylates ribosomal protein L11 using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
1-280 5.84e-91

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 270.89  E-value: 5.84e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986   1 MNdYTEVRIDmspCNETMTDVMAALLCEHGYESFV--------PDENGMTAYIKLEDFDKKVLDEVTAELPFDTSVTVKC 72
Cdd:COG2264     1 MK-WIELTIT---TPEEAAEALSDALEELGAEGVEiedappglWERVGVKAYFPEDEDLEELLAALAEALGELGAPEITV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986  73 ETVEGRDWNQEWEKnYFKPITVDGKCVIHSSFHTDIP-SMPYDIVIDPKMAFGTGHHQTTTLIILRLLELPLEGSSVIDM 151
Cdd:COG2264    77 EEVEEEDWVEEWKK-YFKPIRVGDRLVIVPSWEEYEPdPGEIVIEIDPGMAFGTGTHPTTRLCLEALEKLLKPGKTVLDV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 152 GTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNR-HPEINVVLGDASAlagVEPVDLFLANINRNIIVGDLQVY 230
Cdd:COG2264   156 GCGSGILAIAAAKLGAKRVLAVDIDPVAVEAARENAELNGvEDRIEVVLGDLLE---DGPYDLVVANILANPLIELAPDL 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1518538986 231 ASRLKEGGTMLLSGFYEDDIAIVLDEARKHGLEYVGHTVLERWSCLELKK 280
Cdd:COG2264   233 AALLKPGGYLILSGILEEQADEVLAAYEAAGFELVERRERGEWVALVLRK 282
 
Name Accession Description Interval E-value
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
1-280 5.84e-91

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 270.89  E-value: 5.84e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986   1 MNdYTEVRIDmspCNETMTDVMAALLCEHGYESFV--------PDENGMTAYIKLEDFDKKVLDEVTAELPFDTSVTVKC 72
Cdd:COG2264     1 MK-WIELTIT---TPEEAAEALSDALEELGAEGVEiedappglWERVGVKAYFPEDEDLEELLAALAEALGELGAPEITV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986  73 ETVEGRDWNQEWEKnYFKPITVDGKCVIHSSFHTDIP-SMPYDIVIDPKMAFGTGHHQTTTLIILRLLELPLEGSSVIDM 151
Cdd:COG2264    77 EEVEEEDWVEEWKK-YFKPIRVGDRLVIVPSWEEYEPdPGEIVIEIDPGMAFGTGTHPTTRLCLEALEKLLKPGKTVLDV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 152 GTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNR-HPEINVVLGDASAlagVEPVDLFLANINRNIIVGDLQVY 230
Cdd:COG2264   156 GCGSGILAIAAAKLGAKRVLAVDIDPVAVEAARENAELNGvEDRIEVVLGDLLE---DGPYDLVVANILANPLIELAPDL 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1518538986 231 ASRLKEGGTMLLSGFYEDDIAIVLDEARKHGLEYVGHTVLERWSCLELKK 280
Cdd:COG2264   233 AALLKPGGYLILSGILEEQADEVLAAYEAAGFELVERRERGEWVALVLRK 282
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
47-280 2.03e-71

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 220.02  E-value: 2.03e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986  47 LEDFDKKVLDEVTAELPFD-TSVTVKCETVEGRDWNQEWEKnYFKPITVDGKCVIHSSFHTDIPSMPYDIVIDPKMAFGT 125
Cdd:PRK00517   22 LMELGALAALANLAGLGLDlGEPTYTIEEVEDEDWEREWKK-YFHPIRIGDRLWIVPSWEDPPDPDEINIELDPGMAFGT 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 126 GHHQTTTLIILRLLELPLEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRhpeinvVLGDASAL 205
Cdd:PRK00517  101 GTHPTTRLCLEALEKLVLPGKTVLDVGCGSGILAIAAAKLGAKKVLAVDIDPQAVEAARENAELNG------VELNVYLP 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1518538986 206 AGVEPVDLFLANINRNIIVGDLQVYASRLKEGGTMLLSGFYEDDIAIVLDEARKHGLEYVGHTVLERWSCLELKK 280
Cdd:PRK00517  175 QGDLKADVIVANILANPLLELAPDLARLLKPGGRLILSGILEEQADEVLEAYEEAGFTLDEVLERGEWVALVGKK 249
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 32-280 4.35e-43

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 148.57  E-value: 4.35e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986  32 ESFVPDENGMTAYIKLEDFDKKVLDEVTAELPFDTSVTVKCETVEGRDWNQEWeKNYFKPITVDGKCVIHSSfHTDIPSM 111
Cdd:pfam06325  49 EERLWDEVRVKALFDEETDALELIAQLAELIGGLDSPKVTVEEVAEEDWARAW-KKYFHPVRIGERLTIVPS-WEDYPEN 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 112 PYDIVI--DPKMAFGTGHHQTTTLIILRLLELPLEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSL 189
Cdd:pfam06325 127 PDALNIelDPGMAFGTGTHPTTKLCLEALERLVKPGESVLDVGCGSGILAIAALKLGAKKVVGVDIDPVAVRAAKENAEL 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 190 NR-HPEINVVL-GDASalagVEPVDLFLANINRNIIVGDLQVYASRLKEGGTMLLSGFYEDDIAIVLdEARKHGLEYVGH 267
Cdd:pfam06325 207 NGvEARLEVYLpGDLP----KEKADVVVANILADPLIELAPDIYALVKPGGYLILSGILKEQAQMVA-EAYSQGFELITV 281

                         250
                  ....*....|...
gi 1518538986 268 TVLERWSCLELKK 280
Cdd:pfam06325 282 EHREEWVCIVGKK 294
prmA TIGR00406
ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an ...
 78-274 4.95e-30

ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an S-adenosyl-L-methionine-dependent methyltransferase required for the modification of ribosomal protein L11. This protein is found in bacteria and (with a probable transit peptide) in Arabidopsis. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273061  Cd Length: 288  Bit Score: 114.16  E-value: 4.95e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986  78 RDWNQEWeKNYFKPITVDGKCVIHSSFHTDIPSMPYDIV-IDPKMAFGTGHHQTTTLIILRLLELPLEGSSVIDMGTGTG 156
Cdd:TIGR00406  93 KDWERAW-KDNFHPVQFGKRFWICPSWRDVPSDEDALIImLDPGLAFGTGTHPTTSLCLEWLEDLDLKDKNVIDVGCGSG 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 157 ILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPEINVVLGDASALAGVEPVDLFLANINRNIIVGDLQVYASRLKE 236
Cdd:TIGR00406 172 ILSIAALKLGAAKVVGIDIDPLAVESARKNAELNQVSDRLQVKLIYLEQPIEGKADVIVANILAEVIKELYPQFSRLVKP 251

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1518538986 237 GGTMLLSGFYEDDIAIVLDearkhgLEYVGHTVLERWS 274
Cdd:TIGR00406 252 GGWLILSGILETQAQSVCD------AYEQGFTVVEIRQ 283
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 148-246 1.64e-09

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 54.36  E-value: 1.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 148 VIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPEINVVLGDASAL--AGVEPVDLFLANINRNIIVG 225
Cdd:cd02440     2 VLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELppEADESFDVIISDPPLHHLVE 81

                          90       100
                  ....*....|....*....|....*
gi 1518538986 226 D----LQVYASRLKEGGTMLLSGFY 246
Cdd:cd02440    82 DlarfLEEARRLLKPGGVLVLTLVL 106
 
Name Accession Description Interval E-value
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
1-280 5.84e-91

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 270.89  E-value: 5.84e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986   1 MNdYTEVRIDmspCNETMTDVMAALLCEHGYESFV--------PDENGMTAYIKLEDFDKKVLDEVTAELPFDTSVTVKC 72
Cdd:COG2264     1 MK-WIELTIT---TPEEAAEALSDALEELGAEGVEiedappglWERVGVKAYFPEDEDLEELLAALAEALGELGAPEITV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986  73 ETVEGRDWNQEWEKnYFKPITVDGKCVIHSSFHTDIP-SMPYDIVIDPKMAFGTGHHQTTTLIILRLLELPLEGSSVIDM 151
Cdd:COG2264    77 EEVEEEDWVEEWKK-YFKPIRVGDRLVIVPSWEEYEPdPGEIVIEIDPGMAFGTGTHPTTRLCLEALEKLLKPGKTVLDV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 152 GTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNR-HPEINVVLGDASAlagVEPVDLFLANINRNIIVGDLQVY 230
Cdd:COG2264   156 GCGSGILAIAAAKLGAKRVLAVDIDPVAVEAARENAELNGvEDRIEVVLGDLLE---DGPYDLVVANILANPLIELAPDL 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1518538986 231 ASRLKEGGTMLLSGFYEDDIAIVLDEARKHGLEYVGHTVLERWSCLELKK 280
Cdd:COG2264   233 AALLKPGGYLILSGILEEQADEVLAAYEAAGFELVERRERGEWVALVLRK 282
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
47-280 2.03e-71

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 220.02  E-value: 2.03e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986  47 LEDFDKKVLDEVTAELPFD-TSVTVKCETVEGRDWNQEWEKnYFKPITVDGKCVIHSSFHTDIPSMPYDIVIDPKMAFGT 125
Cdd:PRK00517   22 LMELGALAALANLAGLGLDlGEPTYTIEEVEDEDWEREWKK-YFHPIRIGDRLWIVPSWEDPPDPDEINIELDPGMAFGT 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 126 GHHQTTTLIILRLLELPLEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRhpeinvVLGDASAL 205
Cdd:PRK00517  101 GTHPTTRLCLEALEKLVLPGKTVLDVGCGSGILAIAAAKLGAKKVLAVDIDPQAVEAARENAELNG------VELNVYLP 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1518538986 206 AGVEPVDLFLANINRNIIVGDLQVYASRLKEGGTMLLSGFYEDDIAIVLDEARKHGLEYVGHTVLERWSCLELKK 280
Cdd:PRK00517  175 QGDLKADVIVANILANPLLELAPDLARLLKPGGRLILSGILEEQADEVLEAYEEAGFTLDEVLERGEWVALVGKK 249
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 32-280 4.35e-43

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 148.57  E-value: 4.35e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986  32 ESFVPDENGMTAYIKLEDFDKKVLDEVTAELPFDTSVTVKCETVEGRDWNQEWeKNYFKPITVDGKCVIHSSfHTDIPSM 111
Cdd:pfam06325  49 EERLWDEVRVKALFDEETDALELIAQLAELIGGLDSPKVTVEEVAEEDWARAW-KKYFHPVRIGERLTIVPS-WEDYPEN 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 112 PYDIVI--DPKMAFGTGHHQTTTLIILRLLELPLEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSL 189
Cdd:pfam06325 127 PDALNIelDPGMAFGTGTHPTTKLCLEALERLVKPGESVLDVGCGSGILAIAALKLGAKKVVGVDIDPVAVRAAKENAEL 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 190 NR-HPEINVVL-GDASalagVEPVDLFLANINRNIIVGDLQVYASRLKEGGTMLLSGFYEDDIAIVLdEARKHGLEYVGH 267
Cdd:pfam06325 207 NGvEARLEVYLpGDLP----KEKADVVVANILADPLIELAPDIYALVKPGGYLILSGILKEQAQMVA-EAYSQGFELITV 281

                         250
                  ....*....|...
gi 1518538986 268 TVLERWSCLELKK 280
Cdd:pfam06325 282 EHREEWVCIVGKK 294
prmA TIGR00406
ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an ...
 78-274 4.95e-30

ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an S-adenosyl-L-methionine-dependent methyltransferase required for the modification of ribosomal protein L11. This protein is found in bacteria and (with a probable transit peptide) in Arabidopsis. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273061  Cd Length: 288  Bit Score: 114.16  E-value: 4.95e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986  78 RDWNQEWeKNYFKPITVDGKCVIHSSFHTDIPSMPYDIV-IDPKMAFGTGHHQTTTLIILRLLELPLEGSSVIDMGTGTG 156
Cdd:TIGR00406  93 KDWERAW-KDNFHPVQFGKRFWICPSWRDVPSDEDALIImLDPGLAFGTGTHPTTSLCLEWLEDLDLKDKNVIDVGCGSG 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 157 ILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPEINVVLGDASALAGVEPVDLFLANINRNIIVGDLQVYASRLKE 236
Cdd:TIGR00406 172 ILSIAALKLGAAKVVGIDIDPLAVESARKNAELNQVSDRLQVKLIYLEQPIEGKADVIVANILAEVIKELYPQFSRLVKP 251

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1518538986 237 GGTMLLSGFYEDDIAIVLDearkhgLEYVGHTVLERWS 274
Cdd:TIGR00406 252 GGWLILSGILETQAQSVCD------AYEQGFTVVEIRQ 283
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
143-217 7.41e-15

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 71.47  E-value: 7.41e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1518538986 143 LEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSlNRHPEINVVLGDASALAGVEPVDLFLAN 217
Cdd:COG2263    44 IEGKTVLDLGCGTGMLAIGAALLGAKKVVGVDIDPEALEIARENAE-RLGVRVDFIRADVTRIPLGGSVDTVVMN 117
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 145-263 3.99e-12

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 64.40  E-value: 3.99e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 145 GSSVIDMGTGTGILAILAAMRGAG-PVTAIEIDEFAHVNAVENVSLNR-HPEINVVLGD---ASALAGVEPVDLFLAN-- 217
Cdd:COG4123    38 GGRVLDLGTGTGVIALMLAQRSPGaRITGVEIQPEAAELARRNVALNGlEDRITVIHGDlkeFAAELPPGSFDLVVSNpp 117

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1518538986 218 ------------INRNI----IVGDLQVY----ASRLKEGG--TMLLSGFYEDDIaivLDEARKHGLE 263
Cdd:COG4123   118 yfkagsgrkspdEARAIarheDALTLEDLiraaARLLKPGGrfALIHPAERLAEI---LAALRKYGLG 182
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
144-241 1.86e-11

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 62.36  E-value: 1.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 144 EGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPE-INVVLGDASALAGVEPVDLFLANINRNI 222
Cdd:COG4076    35 PGDVVLDIGTGSGLLSMLAARAGAKKVYAVEVNPDIAAVARRIIAANGLSDrITVINADATDLDLPEKADVIISEMLDTA 114

                          90       100
                  ....*....|....*....|....*
gi 1518538986 223 IVGDLQV----YASR--LKEGGTML 241
Cdd:COG4076   115 LLDEGQVpilnHARKrlLKPGGRII 139
PRK14967 PRK14967
putative methyltransferase; Provisional
 145-217 3.66e-11

putative methyltransferase; Provisional


Pssm-ID: 184931 [Multi-domain]  Cd Length: 223  Bit Score: 61.22  E-value: 3.66e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1518538986 145 GSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPeINVVLGDASALAGVEPVDLFLAN 217
Cdd:PRK14967   37 GRRVLDLCTGSGALAVAAAAAGAGSVTAVDISRRAVRSARLNALLAGVD-VDVRRGDWARAVEFRPFDVVVSN 108
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 104-242 7.63e-10

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 56.48  E-value: 7.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 104 FHTDIPSMPYDIVIDPKMAF--GTGHHQTTTL---------IILRLLELPlEGSSVIDMGTGTGILAILAAMRGAGPVTA 172
Cdd:COG2230     1 HHYDLGNDFYRLFLDPTMTYscAYFEDPDDTLeeaqeakldLILRKLGLK-PGMRVLDIGCGWGGLALYLARRYGVRVTG 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1518538986 173 IEIDEFAHVNAVENV-SLNRHPEINVVLGDASALAGVEPVDLFLAnINRNIIVGD------LQVYASRLKEGGTMLL 242
Cdd:COG2230    80 VTLSPEQLEYARERAaEAGLADRVEVRLADYRDLPADGQFDAIVS-IGMFEHVGPenypayFAKVARLLKPGGRLLL 155
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 148-246 1.64e-09

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 54.36  E-value: 1.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 148 VIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPEINVVLGDASAL--AGVEPVDLFLANINRNIIVG 225
Cdd:cd02440     2 VLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELppEADESFDVIISDPPLHHLVE 81

                          90       100
                  ....*....|....*....|....*
gi 1518538986 226 D----LQVYASRLKEGGTMLLSGFY 246
Cdd:cd02440    82 DlarfLEEARRLLKPGGVLVLTLVL 106
PRK14968 PRK14968
putative methyltransferase; Provisional
 144-201 7.97e-09

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 54.13  E-value: 7.97e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 144 EGSSVIDMGTGTGILAILAAMRGAgPVTAIEIDEFAHVNAVENVSLN--RHPEINVVLGD 201
Cdd:PRK14968   23 KGDRVLEVGTGSGIVAIVAAKNGK-KVVGVDINPYAVECAKCNAKLNniRNNGVEVIRSD 81
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 130-217 8.79e-09

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 55.16  E-value: 8.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 130 TTTLIILRLLELP-LEGSSVIDMGTGTGILAI-LAAMRGAGPVTAIEIDEFAHVNAVENVSLNR-HPEINVVLGDA-SAL 205
Cdd:COG2890    97 TEELVELALALLPaGAPPRVLDLGTGSGAIALaLAKERPDARVTAVDISPDALAVARRNAERLGlEDRVRFLQGDLfEPL 176

                          90
                  ....*....|..
gi 1518538986 206 AGVEPVDLFLAN 217
Cdd:COG2890   177 PGDGRFDLIVSN 188
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 135-279 2.43e-08

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 53.00  E-value: 2.43e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 135 ILRLLELPlEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPEINVVLGDASALAGV--EPVD 212
Cdd:COG0500    18 LALLERLP-KGGRVLDLGCGTGRNLLALAARFGGRVIGIDLSPEAIALARARAAKAGLGNVEFLVADLAELDPLpaESFD 96

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1518538986 213 LFLAN-----INRNIIVGDLQVYASRLKEGGTMLLSGFyedDIAIVLDEARKHGLEYVG---HTVLERWSCLELK 279
Cdd:COG0500    97 LVVAFgvlhhLPPEEREALLRELARALKPGGVLLLSAS---DAAAALSLARLLLLATASlleLLLLLRLLALELY 168
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 135-263 3.07e-08

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 51.53  E-value: 3.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 135 ILRLLELPlEGSSVIDMGTGTGILAILAAMRGAgPVTAIEIDEFAHVNAVENVSlNRHPEINVVLGDASALA-------- 206
Cdd:COG2226    14 LLAALGLR-PGARVLDLGCGTGRLALALAERGA-RVTGVDISPEMLELARERAA-EAGLNVEFVVGDAEDLPfpdgsfdl 90

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1518538986 207 --------GVEPVDLFLANINRniivgdlqvyasRLKEGGTMLLSGFYEDDIAIVLDEARKHGLE 263
Cdd:COG2226    91 vissfvlhHLPDPERALAEIAR------------VLKPGGRLVVVDFSPPDLAELEELLAEAGFE 143
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 138-243 4.49e-08

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 50.79  E-value: 4.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 138 LLELPLEGSSVIDMGTGTGILAILAAMRGAgPVTAIEIDEFAHVNAVENVslnRHPEINVVLGDASALA-GVEPVDLFLA 216
Cdd:COG2227    18 LARLLPAGGRVLDVGCGTGRLALALARRGA-DVTGVDISPEALEIARERA---AELNVDFVQGDLEDLPlEDGSFDLVIC 93

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1518538986 217 NinrNII--VGD----LQVYASRLKEGGTMLLS 243
Cdd:COG2227    94 S---EVLehLPDpaalLRELARLLKPGGLLLLS 123
COG3963 COG3963
Phosphatidylethanolamine N-methyltransferase [Lipid transport and metabolism];
148-241 8.03e-08

Phosphatidylethanolamine N-methyltransferase [Lipid transport and metabolism];


Pssm-ID: 443163  Cd Length: 193  Bit Score: 51.36  E-value: 8.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 148 VIDMGTGTGIL--AILAAMRGAGPVTAIEID-EFA-HVNAvenvslnRHPEINVVLGDASALA------GVEPVD----- 212
Cdd:COG3963    49 VVELGPGTGVFtrAILARGVPDARLLAVEINpEFAeHLRR-------RFPRVTVVNGDAEDLAellaehGIGKVDavvsg 121

                          90       100
                  ....*....|....*....|....*....
gi 1518538986 213 LFLANINRNIIVGDLQVYASRLKEGGTML 241
Cdd:COG3963   122 LPLLSFPPELRRAILDAAFRVLAPGGVFV 150
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 132-242 1.03e-07

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 50.96  E-value: 1.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 132 TLIILRLLELPLEGSsVIDMGTGTGILAILAAMRGAGP-VTAIEIDEFAHVNAVENVSLNRHPEINVVLGDasALAGVEP 210
Cdd:COG2813    38 TRLLLEHLPEPLGGR-VLDLGCGYGVIGLALAKRNPEArVTLVDVNARAVELARANAAANGLENVEVLWSD--GLSGVPD 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1518538986 211 --VDLFLAN--------INRNIIVGDLQVYASRLKEGGTMLL 242
Cdd:COG2813   115 gsFDLILSNppfhagraVDKEVAHALIADAARHLRPGGELWL 156
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
144-243 2.71e-07

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 47.90  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 144 EGSSVIDMGTGTGIL-AILAAMRGAGPVTAIEIDEfahvNAVEnVSLNRHPEINVVLGDASALAGVEPVDLFLANinrNI 222
Cdd:COG4106     1 PPRRVLDLGCGTGRLtALLAERFPGARVTGVDLSP----EMLA-RARARLPNVRFVVADLRDLDPPEPFDLVVSN---AA 72

                          90       100
                  ....*....|....*....|....*..
gi 1518538986 223 I--VGDLQVY----ASRLKEGGTMLLS 243
Cdd:COG4106    73 LhwLPDHAALlarlAAALAPGGVLAVQ 99
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 130-217 5.13e-07

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 49.78  E-value: 5.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 130 TTTLI--ILRLLELPlEGSSVIDMGTGTGILAI-LAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPEINVVLGDA-SAL 205
Cdd:PRK09328   93 TEELVewALEALLLK-EPLRVLDLGTGSGAIALaLAKERPDAEVTAVDISPEALAVARRNAKHGLGARVEFLQGDWfEPL 171

                          90
                  ....*....|..
gi 1518538986 206 AGvEPVDLFLAN 217
Cdd:PRK09328  172 PG-GRFDLIVSN 182
Trm5 COG2520
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ...
 136-264 7.19e-07

tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442010 [Multi-domain]  Cd Length: 333  Bit Score: 49.48  E-value: 7.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 136 LRLLELPLEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNR-HPEINVVLGDASALAgvepvDLF 214
Cdd:COG2520   172 LRIAELVKPGERVLDMFAGVGPFSIPIAKRSGAKVVAIDINPDAVEYLKENIRLNKvEDRVTPILGDAREVA-----PEL 246

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1518538986 215 LANINRnIIVGD-------LQVYASRLKEGGTMLL------SGFYEDDIAIVLDEARKHGLEY 264
Cdd:COG2520   247 EGKADR-IIMNLphsadefLDAALRALKPGGVIHYyeivpeEDPFERAEERIEEAAEEAGYEV 308
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 126-241 1.26e-06

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 47.78  E-value: 1.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 126 GHHQTTT--LIILRLLEL--PLEGSSVIDMGTGTGIL-AILAAMrgAGPVTAIEIDEFAHVNAVENVSLNRHPEINVVLG 200
Cdd:COG2518    44 GHGQTISqpYIVARMLEAldLKPGDRVLEIGTGSGYQaAVLARL--AGRVYSVERDPELAERARERLAALGYDNVTVRVG 121

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1518538986 201 DASA-LAGVEPVDLflaninrnIIVG----DL-QVYASRLKEGGTML 241
Cdd:COG2518   122 DGALgWPEHAPFDR--------IIVTaaapEVpEALLEQLAPGGRLV 160
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 148-238 5.79e-06

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 44.09  E-value: 5.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 148 VIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSlNRHPEINVVLGDASALAGV-EPVDLFLAN-----INRN 221
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAA-EAGLNVEFVQGDAEDLPFPdGSFDLVVSSgvlhhLPDP 79

                          90
                  ....*....|....*..
gi 1518538986 222 IIVGDLQVYASRLKEGG 238
Cdd:pfam13649  80 DLEAALREIARVLKPGG 96
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 132-242 1.79e-05

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 44.12  E-value: 1.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 132 TLIILRLLELPLEGSsVIDMGTGTGILAI-LAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPEINVVLGDasALAGVEP 210
Cdd:pfam05175  20 SRLLLEHLPKDLSGK-VLDLGCGAGVLGAaLAKESPDAELTMVDINARALESARENLAANGLENGEVVASD--VYSGVED 96

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1518538986 211 --VDLFLAN--------INRNIIVGDLQVYASRLKEGGTMLL 242
Cdd:pfam05175  97 gkFDLIISNppfhaglaTTYNVAQRFIADAKRHLRPGGELWI 138
RsmD COG0742
16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 139-215 3.98e-05

16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA G966 N2-methylase RsmD is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440505 [Multi-domain]  Cd Length: 183  Bit Score: 43.15  E-value: 3.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 139 LELPLEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDeFAHVNAV-ENV-SLNRHPEINVVLGDA-SALAGV--EPVDL 213
Cdd:COG0742    36 LGPDIEGARVLDLFAGSGALGLEALSRGAASVVFVEKD-RKAAAVIrKNLeKLGLEDRARVIRGDAlRFLKRLagEPFDL 114


                  ...
gi 1518538986 214 -FL 215
Cdd:COG0742   115 vFL 117
COG2521 COG2521
Predicted archaeal methyltransferase [General function prediction only];
142-205 4.39e-05

Predicted archaeal methyltransferase [General function prediction only];


Pssm-ID: 442011 [Multi-domain]  Cd Length: 285  Bit Score: 44.13  E-value: 4.39e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 142 PLEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEfahvNAVENVSLN------RHPEINVVLGDASAL 205
Cdd:COG2521   130 VRRGDRVLDTCTGLGYTAIEALKRGAREVITVEKDP----NVLELAELNpwsrelANERIKIILGDASEV 195
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 147-261 4.53e-05

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 42.86  E-value: 4.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 147 SVIDMGTGTGI--LAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPE-INVVLGDA----SALAGvEPVDLFLANIN 219
Cdd:COG4122    19 RILEIGTGTGYstLWLARALPDDGRLTTIEIDPERAAIARENFARAGLADrIRLILGDAlevlPRLAD-GPFDLVFIDAD 97

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1518538986 220 RNIIVGDLQVYASRLKEGGTMLLsgfyeDDI---AIVLDEARKHG 261
Cdd:COG4122    98 KSNYPDYLELALPLLRPGGLIVA-----DNVlwhGRVADPARRDP 137
CobL COG2242
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part ...
 133-264 5.75e-05

Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 441843 [Multi-domain]  Cd Length: 403  Bit Score: 44.00  E-value: 5.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 133 LIILRLLELPlEGSSVIDMGTGTGILAILAAMRG-AGPVTAIEIDEFAHVNAVENVSlnRH--PEINVVLGDA-SALAGV 208
Cdd:COG2242   237 ALTLAKLALR-PGDVLWDIGAGSGSVSIEAARLApGGRVYAIERDPERAALIRANAR--RFgvPNVEVVEGEApEALADL 313

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1518538986 209 EPVDLflaninrnIIVGD--------LQVYASRLKEGGTMLLSGFYEDDIAIVLDEARKHGLEY 264
Cdd:COG2242   314 PDPDA--------VFIGGsggnlpeiLEACWARLRPGGRLVANAVTLETLALALEALAELGYGG 369
TrmA COG2265
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ...
 127-202 6.75e-05

tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441866 [Multi-domain]  Cd Length: 377  Bit Score: 43.63  E-value: 6.75e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1518538986 127 HHQTTTLI--ILRLLELpLEGSSVIDMGTGTGILAILAAmRGAGPVTAIEIDEFAHVNAVENVSLNRHPEINVVLGDA 202
Cdd:COG2265   215 PEQAEALYaaALEWLDL-TGGERVLDLYCGVGTFALPLA-RRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDL 290
TIGR00095 TIGR00095
16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; This model represents a family of ...
 143-280 8.74e-05

16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; This model represents a family of uncharacterized bacterial proteins. Members are present in nearly every complete bacterial genome, always in a single copy. PSI-BLAST analysis shows homology to several families of SAM-dependent methyltransferases, including ribosomal RNA adenine dimethylases. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 188022 [Multi-domain]  Cd Length: 190  Bit Score: 42.40  E-value: 8.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 143 LEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVS-LNRHPEINVVLGDASALAgvepvdLFLA--NIN 219
Cdd:TIGR00095  49 IVGAHFLDLFAGSGALGLEALSRGAASAVFVEQDRKVAQTLKENLStLKKSGEQATVLNDAVRAL------LFLAkkQTP 122

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1518538986 220 RNIIVGDlQVYASRLKEGGTMLL--SGFYEDDIAIVLDEARKHGLEyvghTVLERWSCLELKK 280
Cdd:TIGR00095 123 FDIIYLD-PPFNRGLLEALLELLgeNKWLNPKGLIVVEYDRENELP----TVPETWSLLRQKV 180
RsmA COG0030
16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase ...
 135-218 1.78e-04

16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity) [Translation, ribosomal structure and biogenesis]; 16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity) is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 439801 [Multi-domain]  Cd Length: 270  Bit Score: 42.03  E-value: 1.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 135 ILRLLElPLEGSSVIDMGTGTGIL--AILAAmrgAGPVTAIEIDE--FAHVNAVenvsLNRHPEINVVLGDA-----SAL 205
Cdd:COG0030    29 IVDAAG-ITPGDTVLEIGPGLGALtrALLER---AARVTAVEIDRrlAAILRET----FAAYPNLTVIEGDAlkvdlPAL 100

                          90
                  ....*....|...
gi 1518538986 206 AGVEPVDLFlANI 218
Cdd:COG0030   101 AAGEPLKVV-GNL 112
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 133-214 1.99e-04

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 41.68  E-value: 1.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 133 LIILRLLELPleGSSVIDMGTGTGIL--AILAAMRGAGPVTAIEIDEFAHVNAVENVS-LNRHPEINVVLGDASALAGVE 209
Cdd:COG2519    82 YIIARLDIFP--GARVLEAGTGSGALtlALARAVGPEGKVYSYERREDFAEIARKNLErFGLPDNVELKLGDIREGIDEG 159


                  ....*
gi 1518538986 210 PVDLF 214
Cdd:COG2519   160 DVDAV 164
PLN02585 PLN02585
magnesium protoporphyrin IX methyltransferase
 125-175 3.82e-04

magnesium protoporphyrin IX methyltransferase


Pssm-ID: 215319 [Multi-domain]  Cd Length: 315  Bit Score: 41.38  E-value: 3.82e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1518538986 125 TGHHQTTTLIiLRLL--ELPLEGSSVIDMGTGTGILAILAAMRGAGpVTAIEI 175
Cdd:PLN02585  124 LGHAQTVEKV-LLWLaeDGSLAGVTVCDAGCGTGSLAIPLALEGAI-VSASDI 174
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 126-177 4.25e-04

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 40.59  E-value: 4.25e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1518538986 126 GHHQTTTLIILRLLELP-LEGSSVIDMGTGTGILAILAAMRGAGpVTAIEIDE 177
Cdd:PRK07580   44 GHQRMRDTVLSWLPADGdLTGLRILDAGCGVGSLSIPLARRGAK-VVASDISP 95
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 134-196 6.24e-04

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 39.33  E-value: 6.24e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1518538986 134 IILRLLELPLEGSSVIDMGTGTGILAILAAMRGAgPVTAIEIDEFAHVNAVENVSLNRHPEIN 196
Cdd:pfam13489  12 LLLRLLPKLPSPGRVLDFGCGTGIFLRLLRAQGF-SVTGVDPSPIAIERALLNVRFDQFDEQE 73
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
135-270 9.43e-04

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 39.21  E-value: 9.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 135 ILRLLeLPLEGSSVIDMGTGTGILAILAAMRGaGPVTAIEIDEfahvNAVEnVSLNRHPEINVVLGDASALAGV-EPVDL 213
Cdd:COG4976    38 LLARL-PPGPFGRVLDLGCGTGLLGEALRPRG-YRLTGVDLSE----EMLA-KAREKGVYDRLLVADLADLAEPdGRFDL 110

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1518538986 214 FLANinrNII--VGDLQ-----VYASrLKEGGTMLLS-------GFYEDDIAIVLDEARKHGLEYVGHTVL 270
Cdd:COG4976   111 IVAA---DVLtyLGDLAavfagVARA-LKPGGLFIFSvedadgsGRYAHSLDYVRDLLAAAGFEVPGLLVV 177
Cons_hypoth95 pfam03602
Conserved hypothetical protein 95;
143-205 1.03e-03

Conserved hypothetical protein 95;


Pssm-ID: 427391 [Multi-domain]  Cd Length: 179  Bit Score: 39.14  E-value: 1.03e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1518538986 143 LEGSSVIDMGTGTGILAILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPEINVVLGDASAL 205
Cdd:pfam03602  40 IEGARVLDLFAGSGALGLEALSRGAKRVTLVEKDKRAVQILKENLQLLGLPGAVLVMDALLAL 102
YtxK COG0827
Adenine-specific DNA N6-methylase [Replication, recombination and repair];
126-249 1.05e-03

Adenine-specific DNA N6-methylase [Replication, recombination and repair];


Pssm-ID: 440589 [Multi-domain]  Cd Length: 327  Bit Score: 39.93  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518538986 126 GHHQTT----TLIILRLLE--LPLEGSSVIDMGTGTGIL--AILAAMRGAGPVTAIEIDEFAHVNAVENVSLNRHPeINV 197
Cdd:COG0827    91 PNHQMTpdaiGLLIGYLVEkfTKKEGLRILDPAVGTGNLltTVLNQLKKKVNAYGVEVDDLLIRLAAVLANLQGHP-VEL 169

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1518538986 198 VLGDASALAGVEPVDLflaninrniIVGDLQVyasrlkeggtmllsGFYEDD 249
Cdd:COG0827   170 FHQDALQPLLIDPVDV---------VISDLPV--------------GYYPND 198
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 144-205 5.08e-03

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 36.85  E-value: 5.08e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1518538986 144 EGSSVID--MGTGTgiLAILAAMRGAgPVTAIEIDEFAHVNAVENVSLNRHPEINVVLGDASAL 205
Cdd:COG1041    26 EGDTVLDpfCGTGT--ILIEAGLLGR-RVIGSDIDPKMVEGARENLEHYGYEDADVIRGDARDL 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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