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Conserved domains on  [gi|1518539006|ref|WP_123396457|]
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MULTISPECIES: PepSY-like domain-containing protein [Muribaculum]

Protein Classification

PepSY-like domain-containing protein( domain architecture ID 10568455)

PepSY-like domain-containing protein similar to Bacteroides vulgatus BVU2987 that adopts a beta-lactamase inhibitor protein-like structure and may function as an inhibitory protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PepSY_like pfam11396
Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is ...
 64-142 7.39e-20

Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is probably periplasmic. Members are found predominantly in microbes of the human gut and oral cavity. Structurally, one member of this family is found to show similarity to the beta-lactamase-inhibitor PepSY proteins, so the overall function may be inhibitory. There are tandem repeats of the domain on many family members.


:

Pssm-ID: 431867  Cd Length: 83  Bit Score: 78.08  E-value: 7.39e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518539006  64 YDVKLVNGTKIEFNNAGKWTSVDCKTREVPQGLIMKPIRNYLKKN-FNDEKVVKIEKKSWGYELELSDGVELKFNLLGQF 142
Cdd:pfam11396   2 YDVDFTDGTEVEFDKKGNWKETECKYTDVPLDILPAAVAKYFKASnYPDEDVVKIERPKTGYEIELENGVELYFDPKGNL 81
 
Name Accession Description Interval E-value
PepSY_like pfam11396
Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is ...
 64-142 7.39e-20

Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is probably periplasmic. Members are found predominantly in microbes of the human gut and oral cavity. Structurally, one member of this family is found to show similarity to the beta-lactamase-inhibitor PepSY proteins, so the overall function may be inhibitory. There are tandem repeats of the domain on many family members.


Pssm-ID: 431867  Cd Length: 83  Bit Score: 78.08  E-value: 7.39e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518539006  64 YDVKLVNGTKIEFNNAGKWTSVDCKTREVPQGLIMKPIRNYLKKN-FNDEKVVKIEKKSWGYELELSDGVELKFNLLGQF 142
Cdd:pfam11396   2 YDVDFTDGTEVEFDKKGNWKETECKYTDVPLDILPAAVAKYFKASnYPDEDVVKIERPKTGYEIELENGVELYFDPKGNL 81
 
Name Accession Description Interval E-value
PepSY_like pfam11396
Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is ...
 64-142 7.39e-20

Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is probably periplasmic. Members are found predominantly in microbes of the human gut and oral cavity. Structurally, one member of this family is found to show similarity to the beta-lactamase-inhibitor PepSY proteins, so the overall function may be inhibitory. There are tandem repeats of the domain on many family members.


Pssm-ID: 431867  Cd Length: 83  Bit Score: 78.08  E-value: 7.39e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518539006  64 YDVKLVNGTKIEFNNAGKWTSVDCKTREVPQGLIMKPIRNYLKKN-FNDEKVVKIEKKSWGYELELSDGVELKFNLLGQF 142
Cdd:pfam11396   2 YDVDFTDGTEVEFDKKGNWKETECKYTDVPLDILPAAVAKYFKASnYPDEDVVKIERPKTGYEIELENGVELYFDPKGNL 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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