|
Name |
Accession |
Description |
Interval |
E-value |
| PBP1_ABC_LIVBP-like |
cd06342 |
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active ... |
29-365 |
1.71e-146 |
|
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.
Pssm-ID: 380565 [Multi-domain] Cd Length: 334 Bit Score: 418.08 E-value: 1.71e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtspKIGGKPVKFVLETQDDQADPRTGTTVAQKLVDDGIKGMLGHFNSG 108
Cdd:cd06342 1 KIGVAGPLTGPNAALGQDIRNGAELAVDEINA---KGGGLGFKIELVAQDDACDPAQAVAAAQKLVADGVVAVIGHYNSG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 109 TTIPASRIYANAGIPQIA-MATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFEK 187
Cdd:cd06342 78 AAIAAAPIYAEAGIPMISpSATNPKLTEQGYKNFFRVVGTDDQQGPAAADYAAKTLKAKRVAVIHDGTAYGKGLADAFKK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 188 AAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAGNA 267
Cdd:cd06342 158 ALKALGGTVVGREGITPGTTDFSALLTKIKAANPDAVYFGGYYPEAGLLLRQLREAGLKAPFMGGDGIVSPDFIKAAGDA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 268 ADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKYLPVLAKTDMAGVTsSHV 347
Cdd:cd06342 238 AEGVYATTPGAPPEKLPAAKAFLKAYKAKFGEPPGAYAAYAYDAAQVLLAAIEKAGSTDRAAVAAALRATDFDGVT-GTI 316
|
330
....*....|....*...
gi 1525863046 348 AYDAKGDLKNGGITMYKV 365
Cdd:cd06342 317 SFDAKGDLTGPAFTVYQV 334
|
|
| LivK |
COG0683 |
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ... |
25-375 |
2.47e-86 |
|
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];
Pssm-ID: 440447 [Multi-domain] Cd Length: 314 Bit Score: 264.10 E-value: 2.47e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 25 ADDVKIGYAGPMTGAQAHYGKDMQNGIALALEDFNATsPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLVD-DGIKGMLG 103
Cdd:COG0683 1 ADPIKIGVLLPLTGPYAALGQPIKNGAELAVEEINAA-GGVLGRKIELVVE--DDASDPDTAVAAARKLIDqDKVDAIVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 104 HFNSGTTIPASRIYANAGIPQIAM-ATAPEYTQQ-GYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGL 181
Cdd:COG0683 78 PLSSGVALAVAPVAEEAGVPLISPsATAPALTGPeCSPYVFRTAPSDAQQAEALADYLAKKLGAKKVALLYDDYAYGQGL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 182 ADQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMsgemvktptfl 261
Cdd:COG0683 158 AAAFKAALKAAGGEVVGEEYYPPGTTDFSAQLTKIKAAGPDAVFLAGYGGDAALFIKQAREAGLKGPLN----------- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 262 kiagnaadgtiaslaglpleempggKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKYLPVLAKTDMAG 341
Cdd:COG0683 227 -------------------------KAFVKAYKAKYGREPSSYAAAGYDAALLLAEAIEKAGSTDREAVRDALEGLKFDG 281
|
330 340 350
....*....|....*....|....*....|....*
gi 1525863046 342 VTSShVAYDAKGDLKNgGITMYKVEK-GEWKPLKS 375
Cdd:COG0683 282 VTGP-ITFDPDGQGVQ-PVYIVQVKAdGKFVVVET 314
|
|
| PBP1_ABC_HAAT-like |
cd06349 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-370 |
2.28e-83 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380572 [Multi-domain] Cd Length: 338 Bit Score: 257.11 E-value: 2.28e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKfvLETQDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd06349 1 KIGVSGPLTGDNAEYGQQFKNGVELAVDEINA-AGGVNGRKLE--LVVYDDQGDPKEAVNIAQKFVsDDKVVAVIGDFSS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFEK 187
Cdd:cd06349 78 SCSMAAAPIYEEAGLVQISPTASHPDFTKGGDYVFRNSPTQAVEAPFLADYAVKKLGAKKIAIIYLNTDWGVSAADAFKK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 188 AAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAGNA 267
Cdd:cd06349 158 AAKALGGEIVATEAYLPGTKDFSAQITKIKNANPDAIYLAAYYNDAALIAKQARQLGWDVQIFGSSSLYSPEFIELAGDA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 268 ADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADsTDPAKYLPVLAKTDMAGVTSSHV 347
Cdd:cd06349 238 AEGVYLSSPFFPESPDPEVKEFVKAYKAKYGEDPDDFAARAYDAVNILAEAIEKAG-TDREAIRDALANIKDFSGLTGTI 316
|
330 340
....*....|....*....|...
gi 1525863046 348 AYDAKGDLKNgGITMYKVEKGEW 370
Cdd:cd06349 317 TFDENGDVLK-SLTILVVKDGKF 338
|
|
| PBP1_ABC_LivK_ligand_binding-like |
cd06347 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-354 |
1.99e-81 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380570 [Multi-domain] Cd Length: 334 Bit Score: 252.08 E-value: 1.99e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLVD-DGIKGMLGHFNS 107
Cdd:cd06347 1 KIGVIGPLTGEAAAYGQPALNGAELAVDEINA-AGGILGKKIELIVY--DNKSDPTEAANAAQKLIDeDKVVAIIGPVTS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIA-MATAPEYTQQGyKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRT-AYGQGLADQF 185
Cdd:cd06347 78 SIALAAAPIAQKAKIPMITpSATNPLVTKGG-DYIFRACFTDPFQGAALAKFAYEELGAKKAAVLYDVSsDYSKGLAKAF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAG 265
Cdd:cd06347 157 KEAFEKLGGEIVAEETYTSGDTDFSAQLTKIKAANPDVIFLPGYYEEAALIIKQARELGITAPILGGDGWDSPELLELGG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 266 NAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKYLPVLAKT-DMAGVTs 344
Cdd:cd06347 237 DAVEGVYFTTHFSPDDPSPEVQEFVKAYKAKYGEPPNAFAALGYDAVMLLADAIKRAGSTDPEAIRDALAKTkDFEGVT- 315
|
330
....*....|
gi 1525863046 345 SHVAYDAKGD 354
Cdd:cd06347 316 GTITFDPNGN 325
|
|
| PBP1_ABC_ligand_binding-like |
cd19984 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-315 |
2.64e-77 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380639 [Multi-domain] Cd Length: 296 Bit Score: 240.20 E-value: 2.64e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLVD-DGIKGMLGHFNS 107
Cdd:cd19984 1 KIGVILPLTGDAASYGEDMKNGIELAVEEINA-AGGINGKKIELIYE--DSKCDPKKAVSAANKLINvDKVKAIIGGVCS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQI-AMATAPEYTQQG-YktTFRMMTSDTQQGSVAGTFASKDLgMKKIAIVDDRTAYGQGLADQF 185
Cdd:cd19984 78 SETLAIAPIAEQNKVVLIsPGASSPEITKAGdY--IFRNYPSDAYQGKVLAEFAYNKL-YKKVAILYENNDYGVGLKDVF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAG 265
Cdd:cd19984 155 KKEFEELGGKIVASESFEQGETDFRTQLTKIKAANPDAIFLPGYPKEGGLILKQAKELGIKAPILGSDGFEDPELLEIAG 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1525863046 266 NAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAM 315
Cdd:cd19984 235 EAAEGVIFTYPAFDDSSEKKQKFFFYRYKEKYGKEPDIYAALAYDAVMIL 284
|
|
| PBP1_ABC_HAAT-like |
cd06344 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-356 |
4.72e-75 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380567 [Multi-domain] Cd Length: 332 Bit Score: 235.58 E-value: 4.72e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 27 DVKIGYAGPMTGAqahyGKDMQNGIALALEDFNAtSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLVDD-GIKGMLGHF 105
Cdd:cd06344 1 DIVIGVAWPFAPD----GDLFLEGVELAVEEINA-AGGVLGRKIRLVEY--DDEASVDKGLAIAQRFADNpDVVAVIGHR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 106 NSGTTIPASRIYANAGIPQIA-MATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFAsKDLGMKKIAIVDDRTAYGQGLADQ 184
Cdd:cd06344 74 SSYVAIPASIIYERAGLLMLSpGATAPKLTQHGFKYIFRNIPSDEDIARQLARYA-ARQGYKRIVIYYDDDSYGKGLANA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 185 FEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAA-KPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKI 263
Cdd:cd06344 153 FEEEARELGITIVDRRSYSSDEEDFRRLLSKWKALdFFDAIFLAGSMPEGAEFIKQARELGIKVPIIGGDGLDSPELIEI 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 264 AGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKYLPVL-AKTDMAGV 342
Cdd:cd06344 233 AGKAAEGVVVATVFDPDDPRPEVRAFVEAFRKKYGREPDVWAAQGYDAVKLLAEAIEKAGSTVPAKIASALrFLENWEGV 312
|
330
....*....|....
gi 1525863046 343 TSSHVaYDAKGDLK 356
Cdd:cd06344 313 TGTYS-FDANGDVV 325
|
|
| PBP1_ABC_transporter_LIVBP-like |
cd06268 |
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the ... |
29-323 |
7.73e-75 |
|
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily; Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.
Pssm-ID: 380492 [Multi-domain] Cd Length: 298 Bit Score: 234.14 E-value: 7.73e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd06268 1 KIGVVVPLTGPYADYGEEILRGVALAVEEINA-AGGINGRKLELVIA--DDQGDPETAVAVARKLVdDDKVLAVVGHYSS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIA-MATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFE 186
Cdd:cd06268 78 SVTLAAAPIYQEAGIPLISpGSTAPELTEGGGPYVFRTVPSDAMQAAALADYLAKKLKGKKVAILYDDYDYGKSLADAFK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 187 KAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAGN 266
Cdd:cd06268 158 KALKALGGEIVAEEDFPLGTTDFSAQLTKIKAAGPDVLFLAGYGADAANALKQARELGLKLPILGGDGLYSPELLKLGGE 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1525863046 267 AADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKAD 323
Cdd:cd06268 238 AAEGVVVAVPWHPDSPDPPKQAFVKAYKKKYGGPPSWRAATAYDATQALAGDRVQQP 294
|
|
| PBP1_ABC_ligand_binding-like |
cd19980 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-354 |
2.60e-69 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380635 [Multi-domain] Cd Length: 334 Bit Score: 220.94 E-value: 2.60e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVleTQDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd19980 1 KIGVIAPLSGPVAALGQQVLNGAKLAVEEINA-KGGVLGRKLELV--VEDDKCPPAEGVAAAKKLItDDKVPAIIGAWCS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQI-AMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFE 186
Cdd:cd19980 78 SVTLAVMPVAERAKVPLVvEISSAPKITEGGNPYVFRLNPTNSMLAKAFAKYLADKGKPKKVAFLAENDDYGRGAAEAFK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 187 KAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAGN 266
Cdd:cd19980 158 KALKAKGVKVVATEYFDQGQTDFTTQLTKLKAANPDAIFVVAETEDGALILKQARELGLKQQLVGTGGTTSPDLIKLAGD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 267 AADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKYLPVLAKTDMAGVTSSH 346
Cdd:cd19980 238 AAEGVYGASIYAPTADNPANKAFVAAYKKKYGEPPDKFAALGYDAVMVIAEAIKKAGSTDPEKIRAAALKKVDYKGPGGT 317
|
....*...
gi 1525863046 347 VAYDAKGD 354
Cdd:cd19980 318 IKFDEKGQ 325
|
|
| PRK15404 |
PRK15404 |
high-affinity branched-chain amino acid ABC transporter substrate-binding protein; |
1-357 |
9.64e-65 |
|
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
Pssm-ID: 237959 [Multi-domain] Cd Length: 369 Bit Score: 210.26 E-value: 9.64e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 1 MQHTMKKLAGAtfVAVMSLAGTAHADDVKIGYAGPMTGAQAHYGkDMQ-NGIALALEDFNATSpKIGGKpvKFVLETQDD 79
Cdd:PRK15404 1 MKSKGKTLLAG--CIALALSHAALADDIKIAIVGPMSGPVAQYG-DMEfTGARQAIEDINAKG-GIKGD--KLEGVEYDD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 80 QADPRTGTTVAQKLVDDGIKGMLGHFNSGTTIPASRIYANAGIPQI-AMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTF 158
Cdd:PRK15404 75 ACDPKQAVAVANKVVNDGIKYVIGHLCSSSTQPASDIYEDEGILMItPAATAPELTARGYQLIFRTIGLDSDQGPTAAKY 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 159 ASKDLGMKKIAIVDDRTAYGQGLADQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVK 238
Cdd:PRK15404 155 ILEKVKPKRIAVLHDKQQYGEGLARSVKDGLKKAGANVVFFEGITAGDKDFSALIAKLKKENVDFVYYGGYHPEMGQILR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 239 QMKTLGITAPLMSGEMVKTPTFLKIAGNAADGTiasLAGLP--LEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAML 316
Cdd:PRK15404 235 QAREAGLKTQFMGPEGVGNKSLSNIAGPASEGM---LVTLPkrYDQDPANKAIVDAFKAKKQDPSGPFVWTTYAAVQSLA 311
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1525863046 317 NAMKKADSTDPAKYLPVLAKTDMAGVTSShVAYDAKGDLKN 357
Cdd:PRK15404 312 AGINRAGSDDPAKVAKYLKANTFDTVIGP-LSWDEKGDLKG 351
|
|
| PBP1_ABC_ligand_binding-like |
cd06340 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-363 |
4.87e-64 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380563 [Multi-domain] Cd Length: 352 Bit Score: 207.80 E-value: 4.87e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNA--TSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKGMLGHF 105
Cdd:cd06340 1 KIGVLYPLSGPLALIGQEAKRGAELAVDEINAagGIKSLGGAKIELVVA--DTQSDPEVAASEAERLItQEGVVAIIGAY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 106 NSGTTIPASRIYANAGIPQI-AMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTF-----ASKDLGMKKIAIVDDRTAYGQ 179
Cdd:cd06340 79 SSSVTLAASQVAERYGVPFVtASAVADEITERGFKYVFRTAPTASQFAEDAVDFlkelaKKKGKKIKKVAIIYEDSAFGT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 180 GLADQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLM--SGEMVKT 257
Cdd:cd06340 159 SVAKGLKKAAKKAGLEVVLDEPYPAGATDLSSEVLKLKAAKPDVVFATSYTNDAILLLRTMKELGFKPKAIigVGGGYSD 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 258 PTFLKIAGNAADG--TIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKYLPVLA 335
Cdd:cd06340 239 PEFLKALGKDAEGvfSVVPWSPDLAKKKPGAKEVNERYKKKYGEDMTGHAARAYTAAWVLADALERAGSTDPEAIRAAAA 318
|
330 340 350
....*....|....*....|....*....|..
gi 1525863046 336 KTDMAG----VTSSHVAYDAKGDLKNGGITMY 363
Cdd:cd06340 319 LTLDIPegliMPGGGVKFDEKGQNVLARPVVV 350
|
|
| PBP1_ABC_HAAT-like |
cd19988 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-317 |
8.65e-64 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380643 [Multi-domain] Cd Length: 302 Bit Score: 205.59 E-value: 8.65e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSpKIGGKPVKFVLEtqDDQADPRTGTTVAQKLVD-DGIKGMLGHFNS 107
Cdd:cd19988 1 KIGVFGPLSGDAAPYGQAMLQGAELAVEEINAAG-GILGIPIELVVE--DDEGLPAASVSAAKKLIYqDKVWAIIGSINS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQI-AMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFE 186
Cdd:cd19988 78 SCTLAAIRVALKAGVPQInPGSSAPTITESGNPWVFRCTPDDRQQAYALVDYAFEKLKVTKIAVLYVNDDYGRGGIDAFK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 187 KAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPD-LVYYGGADsQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAG 265
Cdd:cd19988 158 DAAKKYGIEVVVEESYNRGDKDFSPQLEKIKDSGAQaIVMWGQYT-EGALIAKQARELGLKQPLFGSDGLVTPKFIELAG 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1525863046 266 NAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLN 317
Cdd:cd19988 237 DAAEGAIATTPFLPDSDDPKVSAFVEKYKKRYGEEPDVFAAQAYDAMNILAG 288
|
|
| PBP1_ABC_ligand_binding-like |
cd06335 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-329 |
4.15e-60 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380558 [Multi-domain] Cd Length: 348 Bit Score: 197.83 E-value: 4.15e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSpKIGGKPVKfvLETQDDQADPRTGTTVAQKLVD-DGIKGMLGHFNS 107
Cdd:cd06335 1 KIGVIGPLTGPSAELGESARRGVELAVEEINAAG-GILGRKIE--LVERDDEANPTKAVQNAQELIDkEKVVAIIGPTNS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIA-MATAPEYTQQGYKT---TFRMMTSDTQQGSVAGTFAsKDLGMKKIAIVDDRTAYGQGLAD 183
Cdd:cd06335 78 GVALATIPILQEAKIPLIIpVATGTAITKPPAKPrnyIFRVAASDTLQADFLVDYA-VKKGFKKIAILHDTTGYGQGGLK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 184 QFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKI 263
Cdd:cd06335 157 DVEAALKKRGITPVATESFKIGDTDMTPQLLKAKDAGADVILVYGLGPDLAQILKAMEKLGWKVPLVGSWGLSMPNFIEL 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1525863046 264 AGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYA---YDGAMAMLNAMKKADSTDPAK 329
Cdd:cd06335 237 AGPLAEGTIMTQTFIEDYLTPRAKKFIDAYKKKYGTDRIPSPVSAaqgYDAVYLLAAAIKQAGSTDGKK 305
|
|
| PBP1_ABC_ligand_binding-like |
cd06336 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-363 |
1.12e-57 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380559 [Multi-domain] Cd Length: 345 Bit Score: 191.29 E-value: 1.12e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSP-KIGGKPVKFVLETQDDQADPRTGTTVAQKLVD-DGIKGMLGhFN 106
Cdd:cd06336 1 KIGFLGPLSGPAAAWGLPMLRGLELAADEINAAGGiKVGGKKYKVEVVSYDDKYTPAEAVAAARRLVSqDGVKFIFG-PG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 107 SGTTIPASRIYAN-AGIPQIAMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQF 185
Cdd:cd06336 80 GSAIAAAVQPVTErNKVLLLTAAFSDPILGPDNPLLFRIPPTPYEYAPPFIKWLKKNGPIKTVALIAPNDATGKDWAAAF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGAD-SQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIA 264
Cdd:cd06336 160 VAAWKAAGGEVVAEEFYDRGTTDFYPVLTKILALKPDALDLGGSSpGPAGLIIKQARELGFKGPFVSEGGAKADEILKEV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 265 G-NAADGTIASL-AGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKylpvLAKTDMAGV 342
Cdd:cd06336 240 GgEAAEGFIGVLpADDDPIASPGAKAFVERYKKKYGEPPNSESALFYDAAYILVKAMEKAGTVDDTK----KIRAALAML 315
|
330 340
....*....|....*....|.
gi 1525863046 343 TSSHVAYdakGDLKNGGITMY 363
Cdd:cd06336 316 SPDETLF---GKLKWGGKEIY 333
|
|
| PBP1_ABC_RPA1789-like |
cd06333 |
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, ... |
29-329 |
1.37e-57 |
|
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs; This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380556 [Multi-domain] Cd Length: 342 Bit Score: 190.84 E-value: 1.37e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd06333 1 KIGAILSLTGPAASLGIPERNAVELLVEQINA-AGGINGRKLELIVY--DDESDPTKAVTNARKLIeEDKVDAIIGPSTT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAMATAPEYTQQGYKTTFRMMTSDTQqgSVAGTFA-SKDLGMKKIAIVDDRTAYGQGLADQFE 186
Cdd:cd06333 78 GESLAVAPIAEEAKVPLISLAGAAAIVEPVRKWVFKTPQSDSL--VAEAILDyMKKKGIKKVALLGDSDAYGQSGRAALK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 187 KAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAGN 266
Cdd:cd06333 156 KLAPEYGIEIVADERFARTDTDMTAQLTKIRAAKPDAVLVWASGPPAALVAKNLRQLGYKGPIYQSHGAANQDFIKLAGK 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1525863046 267 AADGTI-ASLAGLPLEEMPGG-------KTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAK 329
Cdd:cd06333 236 AAEGVIlPAGKLLVADQLPDSdpqkkvlLEFVKAYEAKYGEGPSTFAGHAYDALLLLVEAIEPAGGTDRAA 306
|
|
| PBP1_ABC_ligand_binding-like |
cd06345 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-343 |
2.61e-57 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380568 [Multi-domain] Cd Length: 356 Bit Score: 190.55 E-value: 2.61e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTgaqAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd06345 1 KIGVLGPLS---APAGEAMERGAELAVEEINA-AGGILGRKVELVVA--DTQGKPEDGVAAAERLItEDKVDAIVGGFRS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAM-ATAPEYTQQ------GYKTTFRMM-TSDTQQGSVAGTFAS---KDLGMKKIAIVDDRTA 176
Cdd:cd06345 75 EVVLAAMEVAAEYKVPFIVTgAASPAITKKvkkdyeKYKYVFRVGpNNSYLGATVAEFLKDllvEKLGFKKVAILAEDAA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 177 YGQGLADQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLM--SGEM 254
Cdd:cd06345 155 WGRGIAEALKKLLPEAGLEVVGVERFPTGTTDFTPILSKIKASGADVIVTIFSGPGGILLVKQWAELGVPAPLVgiNVPA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 255 VKtPTFLKIAGNAADGTIASLAGLPLEEM-PGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKYLPV 333
Cdd:cd06345 235 QD-PEFWENTGGAGEYEITLAFAAPKAKVtPKTKPFVDAYKKKYGEAPNYTAYTAYDAIYILAEAIERAGSTDPDALVKA 313
|
330
....*....|
gi 1525863046 334 LAKTDMAGVT 343
Cdd:cd06345 314 LEKTDYEGVR 323
|
|
| PBP1_ABC_HAAT-like |
cd19981 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-321 |
1.11e-56 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380636 [Multi-domain] Cd Length: 297 Bit Score: 187.11 E-value: 1.11e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSpKIGGKPVKFVLEtqDDQADPRTGTTVAQKLVD-DGIKGMLGHFNS 107
Cdd:cd19981 1 KIGFFAPLTGPAAADGKSALHGAELAVEQINAAG-GINGKKVELVVY--DDQASPKQAVNIAQKLIEqDKVVAVVSGSYS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQI-AMATAPEYTQQGyKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFE 186
Cdd:cd19981 78 GPTRAAAPIFQEAKVPMVsAYAVHPDITKAG-DYVFRVAFLGPVQGRAGAEYAVKDLGAKKVAILTIDNDFGKSLAAGFK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 187 KAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAGN 266
Cdd:cd19981 157 EEAKKLGAEIVSEYAYALGDRDFRPILTKIKSANPDAIYASGYYAEAAPIVKQARELGIKVPIIGQEGYDSPKFIEIAGS 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1525863046 267 AADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKK 321
Cdd:cd19981 237 AAEGVIITTSLNRDSDRPITQKFIKEYRKRYGIDPDMVAASTYDAVMVLAGEVQK 291
|
|
| PBP1_ABC_HAAT-like |
cd19986 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-319 |
4.65e-56 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380641 [Multi-domain] Cd Length: 297 Bit Score: 185.52 E-value: 4.65e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSpKIGGKPVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd19986 1 KIGVVAPLTGPAALNGEYQKNGAQLALEEINAAG-GVLGRPLELVVE--DDQGTNTGAVNAVNKLIsDDKVVAVIGPHYS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFEK 187
Cdd:cd19986 78 TQVLAVSPLVKEAKIPVITGGTSPKLTEQGNPYMFRIRPSDSVSAKALAKYAVEELGAKKIAILYDNDDFGTGGADVVTA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 188 AAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAGNA 267
Cdd:cd19986 158 ALKALGLEPVAVESYNTGDKDFTAQLLKLKNSGADVIIAWGHDAEAALIARQIRQLGLDVPVIGSSSFATPTVLLLAGEA 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1525863046 268 ADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAM 319
Cdd:cd19986 238 LEGIYSVTDFVPSDPDPKVQAFVKKYKAKYGEDPDLYSAWYYDAMYLLAGDG 289
|
|
| PBP1_ABC_ligand_binding-like |
cd06338 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-368 |
2.10e-54 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380561 [Multi-domain] Cd Length: 347 Bit Score: 182.78 E-value: 2.10e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSP-KIGGK--PVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKGMLGH 104
Cdd:cd06338 1 KIGASLSLTGPFAGEGKAQKRGYELWVEDVNAAGGvKGGGKkrPVELVYY--DDQSDPATAVRLYEKLItEDKVDLLLGP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 105 FNSGTTIPASRIYANAGIPQIAM-ATAPEYTQQGYKTTFRM-MTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLA 182
Cdd:cd06338 79 YSSGLTLAAAPVAEKYGIPMIAGgAASDSIFERGYKYVFGVlPPASDYAKGLLDLLAELGPKPKTVAIVYEDDPFGKEVA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 183 DQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEM-VKTPTFL 261
Cdd:cd06338 159 EGAREAAKKAGLEVVYDESYPPGTTDFSPLLTKVKAANPDILLVGGYPPDAITLVRQMKELGYNPKAFFLTVgPAFPAFR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 262 KIAGNAADGTIAS---LAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKYLPVLAKTD 338
Cdd:cd06338 239 EALGKDAEGVLGPsqwEPSLPYKVFPGAKEFVKAYKEKFGEEPSYHAAAAYAAGQVLQQAIEKAGSLDPEKVRDALASLD 318
|
330 340 350
....*....|....*....|....*....|
gi 1525863046 339 MAGVTsSHVAYDAKGDLKNGGITMYKVEKG 368
Cdd:cd06338 319 FDTVY-GPIKFDETGLQIGKPMVVVQWQGG 347
|
|
| Peripla_BP_6 |
pfam13458 |
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ... |
28-343 |
2.05e-50 |
|
Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.
Pssm-ID: 433225 [Multi-domain] Cd Length: 342 Bit Score: 172.07 E-value: 2.05e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 28 VKIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSpKIGGKPVKFVleTQDDQADPRTGTTVAQKLVD-DGIKGMLGHFN 106
Cdd:pfam13458 2 IKIGVLTPLSGPYASSGKSSRAGARAAIEEINAAG-GVNGRKIELV--VADDQGDPDVAAAAARRLVDqDGVDAIVGGVS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 107 SGTTIPASRIYANAGIPqiAMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFE 186
Cdd:pfam13458 79 SAVALAVAEVLAKKGVP--VIGPAALTGEKCSPYVFSLGPTYSAQATALGRYLAKELGGKKVALIGADYAFGRALAAAAK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 187 KAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGIT-------APLMSGEMVKTpt 259
Cdd:pfam13458 157 AAAKAAGGEVVGEVRYPLGTTDFSSQVLQIKASGADAVLLANAGADTVNLLKQAREAGLDakgiklvGLGGDEPDLKA-- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 260 flkIAGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEV-QTYSPYAYDGAMAMLNAMKKADSTDPAKYLPVLAKTD 338
Cdd:pfam13458 235 ---LGGDAAEGVYATVPFFPDLDNPATRAFVAAFAAKYGEAPpTQFAAGGYIAADLLLAALEAAGSPTREAVIAALRALP 311
|
....*
gi 1525863046 339 MAGVT 343
Cdd:pfam13458 312 YDGPF 316
|
|
| PBP1_ABC_ligand_binding-like |
cd06346 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-316 |
3.60e-50 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380569 [Multi-domain] Cd Length: 314 Bit Score: 170.82 E-value: 3.60e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLVD-DGIKGMLGHFNS 107
Cdd:cd06346 1 KIGALLPLTGPLASLGPPMLAAAELAVEEINA-AGGVLGKKVELVVE--DSQTDPTAAVDAARKLVDvEGVPAIVGAASS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAM-ATAPEYTQ-QGYKTTFRMMTSDTQQGSVAGTFAsKDLGMKKIAIVDDRTAYGQGLADQF 185
Cdd:cd06346 78 GVTLAVASVAVPNGVVQISPsSTSPALTTlEDKGYVFRTAPSDALQGVVLAQLA-AERGFKKVAVIYVNNDYGQGLADAF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITA-PLMSGEMVKTPTFLK-I 263
Cdd:cd06346 157 KKAFEALGGTVTASVPYEPGQTSYRAELAQAAAGGPDALVLIGYPEDGATILREALELGLDFtPWIGTDGLKSDDLVEaA 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1525863046 264 AGNAADGTIASLAGLPleEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAML 316
Cdd:cd06346 237 GAEALEGMLGTAPGSP--GSPAYEAFAAAYKAEYGDDPGPFAANAYDAVMLLA 287
|
|
| PBP1_ABC_HAAT-like |
cd19985 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-316 |
4.87e-49 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380640 [Multi-domain] Cd Length: 321 Bit Score: 167.84 E-value: 4.87e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKfvLETQDDQADPRTGTTVAQKLVDDGIKGMLGHFNSG 108
Cdd:cd19985 1 HIAVVGPMSGKSASKGKSMLRGAELYIDQINA-AGGINGKKVK--LDVFDDQNDPDAARKAAQIIVSDKALAVIGHYYSS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 109 TTIPASRIYANAGIPQI-AMATAPEYTQ--QGYkttFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQF 185
Cdd:cd19985 78 ASIAAGKIYKKAGIPAItPSATADAVTRdnPWY---FRVIFNDSLQGRFLANYAKKVLKKDKVSIIYEEDSYGKSLASVF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKAGGATIVDREFTNDKA----VDFKAILTKLKAAK--PDLVYYGGADSQAAPMVKQMKTLGITAPLMSGE------ 253
Cdd:cd19985 155 EATARALGLKVLKKWSFDTDSsqldQNLDQIVDELKKAPdePGVIFLATHADEGAKLIKKLRDAGLKAPIIGPDslases 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1525863046 254 ----MVKTPTFLKIAGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAML 316
Cdd:cd19985 235 faqgFAEYPEEKEEPGYYTDGIYATSPFIFDIANEKAQKFRDTYQKRYGEEPSWIAAFAYDAAMLAI 301
|
|
| PBP1_ABC_ligand_binding-like |
cd19982 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-317 |
6.45e-48 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380637 [Multi-domain] Cd Length: 302 Bit Score: 164.38 E-value: 6.45e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd19982 1 KIGAILSLTGPFAPFGEMFKNGYEMALEEINA-AGGIKGKKLELVIE--DDQSKPQTALAAAEKLVsQDKVPLIVGGYSS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQ-IAMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFE 186
Cdd:cd19982 78 GITLPVAAVAERQKIPLlVPTAADDDITKPGYKYVFRLNPPASIYAKALFDFFKELVKPKTIAILYENTAFGTSVAKAAR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 187 KAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMV--KTPTFLKIA 264
Cdd:cd19982 158 RFAKKRGIEVVADESYDKGATDFKPLLNKVKAANPDVVYMVSYLNDAILLMRQAKELGLNPKLFAGGGAgfTIPEFLKQA 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1525863046 265 GNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLN 317
Cdd:cd19982 238 GPLAEYVVTATLWSPDVKYPGAKEFYEKYKAKYGVEPSYHEAEAYAALYVAAN 290
|
|
| PBP1_ABC_HAAT-like |
cd06348 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-368 |
2.70e-45 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380571 [Multi-domain] Cd Length: 342 Bit Score: 158.94 E-value: 2.70e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVleTQDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd06348 1 KIGVALSLTGPGALYGQSQKNGAQLAVEEINA-AGGVGGVKIELI--VEDTAGDPEQAINAFQKLInQDKVLAILGPTLS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAM-ATAPEYTQQGyKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIV----DDRTAYGqglA 182
Cdd:cd06348 78 SEAFAADPIAQQAKVPVVGIsNTAPGITDIG-PYIFRNSLPEDKVIPPTVKAAKKKYGIKKVAVLydqdDAFTVSG---T 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 183 DQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLK 262
Cdd:cd06348 154 KVFPAALKKNGVEVLDTETFQTGDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGPIVGGNGFNSPDLIK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 263 IAGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADST-DPAKYLPVLAKTDMAG 341
Cdd:cd06348 234 LAGKAAEGVIVGSAWSPDNPDPKNQAFVAAYKEKYGKEPDQFAAQAYDAAYILAEAIKKAGSTtDRADLRDALARILIAK 313
|
330 340 350
....*....|....*....|....*....|
gi 1525863046 342 VTSS---HVAYDAKGDLKnGGITMYKVEKG 368
Cdd:cd06348 314 DFEGplgPFSFDADRDGI-QPPVVLIVKDG 342
|
|
| PBP1_aromatic_compounds-like |
cd06332 |
type 1 periplasmic binding proteins of active transport systems predicted to be involved in ... |
29-343 |
1.49e-44 |
|
type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.
Pssm-ID: 380555 [Multi-domain] Cd Length: 336 Bit Score: 156.60 E-value: 1.49e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATspkIGGKPVKFVLEtqDDQADPRTGTTVAQKLVD-DGIKGMLGHFNS 107
Cdd:cd06332 1 KIGLLAPLTGPFAALGEDMVRGFELALEEVGGE---VAGRKVELVVE--DDAGDPDTAVTKARKLVEqDKVDVLIGPLSG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAMATAPEYTQQ--GYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQF 185
Cdd:cd06332 76 DEGLAVAPYAKEPGVPFINPVAGADDLTQraKAPNFFRTSFTGSQWSAPLGDYAYKELGYKKVATIGSDYAFGYEQAAGF 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKpDLVYYGGADSQAAPMVKQMKTLGI--TAPLMSGEMVKTPTFLKI 263
Cdd:cd06332 156 KRGFEAAGGEVVQEIWVPLGTTDFSPYIAQIPSAD-DAVFAFLGGADAVRFLKQYREFGLkdKIPLIGGGTTVDESVLPA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 264 AGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKA--DSTDPAKYLPVLAKTDMAG 341
Cdd:cd06332 235 MGDAALGIISASHYAEGLDNPENKKFVAAYKKKFGKLPSLYAAGGYDGAQAILEALEAVggDVSDKQALAAALRKVKFDS 314
|
..
gi 1525863046 342 VT 343
Cdd:cd06332 315 PR 316
|
|
| PBP1_ABC_ligand_binding-like |
cd06343 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
25-322 |
1.03e-42 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however its ligand specificity has not been determined experimentally.
Pssm-ID: 380566 [Multi-domain] Cd Length: 355 Bit Score: 152.34 E-value: 1.03e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 25 ADDVKIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSPkIGGKPVKFVLEtqDDQADPRTGTTVAQKLVD-DGIKGMLG 103
Cdd:cd06343 4 DDEIKIGTSLPLSGPAAAYGKPVRAGAAAYFDEVNAAGG-INGRKIELIVE--DDGYDPARAVAAVRKLVEqDKVFAIVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 104 HFNSGTTIPASRIYANAGIPQIAMAT-APEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLA 182
Cdd:cd06343 81 GLGTPTNLAVRPYLNEAGVPQLFPATgASALSPPPKPYTFGVQPSYEDEGRILADYIVETLPAAKVAVLYQNDDFGKDGL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 183 DQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFL- 261
Cdd:cd06343 161 EGLKEALKAYGLEVVAEETYEPGDTDFSSQVLKLKAAGADVVVLGTLPKEAAAALKEAAKLGWKPTFLGSSVSADPTTLa 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1525863046 262 KIAGNAADGTIASLAGLPLEEM--PGGKTYADKYKKRFGEE-VQTYSPYAYDGAMAMLNAMKKA 322
Cdd:cd06343 241 KAGGDAAEGVYSASYLKDPTDAddPAVKEFREAYKKYFPDDpPNAYALYGYAAAQVFVEALKRA 304
|
|
| PBP1_ABC_HAAT-like |
cd19983 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-316 |
1.17e-38 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380638 [Multi-domain] Cd Length: 303 Bit Score: 140.03 E-value: 1.17e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSpKIGGKPVKFVleTQDDQADPRTGTTVAQKLVDDGIKGMLGHFNSG 108
Cdd:cd19983 1 RIGFVGGLTGRYSDLGVQGRNGAQLAVEEINAAG-GINGRPVELI--IRDDQQDPEAAKAADRELIAGGVVAIIGHMTSA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 109 TTIPASRIYANAGIPQI-AMATAPEYT-QQGYktTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRT--AYGQGLADQ 184
Cdd:cd19983 78 MTVAVLPVINEAKVLMIsPTVSTPELSgKDDY--FFRVTPTTRESAQALARYAYNRGGLRRVAVIYDLSnrAYSESWLDN 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 185 FEKAAKAGGATIV-DREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKI 263
Cdd:cd19983 156 FRSEFEALGGRIVaEIPFSSGADVDFSDLARRLLASKPDGLLLVASAVDTAMLAQQIRKLGSKIPLFSSAWAATEELLEL 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1525863046 264 AGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAML 316
Cdd:cd19983 236 GGKAVEGMLFSQAYDRNSSNPRYLAFKEAYEERFGREPSFAAAYAYEAAMVLA 288
|
|
| PBP1_As_SBP-like |
cd06330 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
29-329 |
1.22e-36 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.
Pssm-ID: 380553 [Multi-domain] Cd Length: 342 Bit Score: 135.77 E-value: 1.22e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSPkIGGKPVKFVleTQDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd06330 1 KIGVITPLSGAAAVYGEPARNGAELAVEEINAAGG-ILGRKIELV--VRDDKGKPDEAVRAARELVlQEGVDFLIGTISS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAM-ATAPEYT-QQGYKTTFRM-MTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQ 184
Cdd:cd06330 78 GVALAVAPVAEELKVLFIATdAATDRLTeENFNPYVFRTsPNTYMDAVAAALYAAKKPPDVKRWAGIGPDYEYGRDSWAA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 185 FEKAAKA--GGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYG--GADSQAapMVKQMKTLGITA--PLMSGEMVKTP 258
Cdd:cd06330 158 FKAALKKlkPDVEVVGELWPKLGATDYTAYITALLAAKPDGVFSSlwGGDLVT--FVKQAKPYGLFDktKVVSGLGGGSE 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1525863046 259 TFLKIAGNAADGTIASLAGLP-LEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAK 329
Cdd:cd06330 236 VLQALGKEMPEGLIGGGRYPFgWPDTPLNKAFVEAYRAKYGEYPTYWAYEAYAAVMALKAAIEKAGSTDTDK 307
|
|
| PBP1_alkylbenzenes-like |
cd06360 |
type 1 periplasmic binding component of active transport systems predicted be involved in ... |
29-367 |
1.40e-34 |
|
type 1 periplasmic binding component of active transport systems predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; This group includes the type 1 periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.
Pssm-ID: 380583 [Multi-domain] Cd Length: 357 Bit Score: 130.49 E-value: 1.40e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtspKIGGKPVKFVLEtqDDQADPRTGTTVAQKLVD-DGIKGMLGHFNS 107
Cdd:cd06360 1 KIGVLLPLTGPLAVNGEDVRDGFELYFDEIGN---QVAGRKIELIVE--DDEGKPDVGLTKARKLVErDKVHVLAGIVSS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIpASRIYANA-GIPQIAM-ATAPEYTQ-QGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQ 184
Cdd:cd06360 76 AVAY-AVRDYVVEqKIPLVISnAGAAPLTQeLASPYIFRTSFSNGQYDAPFGQYAYEKLGYRRIAVMASDYAAGHEQAGA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 185 FEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITA--PLMSGEMVKTPTFLK 262
Cdd:cd06360 155 FARTFKQAGGKVVQEIYPPLGTADFAPYLARIQQDAADAVWAFFAGADAIRFVKQYDEYGLKGklPLVGIGGLVDDAILP 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 263 IAGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMK--KADSTDPAKYLPVLAKTDMA 340
Cdd:cd06360 235 EQGDAALGIVSYLHYSAALDTPENKAFVQAYRKKYGRDPGLYAEGGYVAARAIAEALEavKGNVEDKEAFLEALRKVRFE 314
|
330 340
....*....|....*....|....*....
gi 1525863046 341 GvTSSHVAYDAKGdlkNGGITMY--KVEK 367
Cdd:cd06360 315 A-PRGPFRFDPYQ---QAVVTTYirRVEK 339
|
|
| PBP1_RPA0668_benzoate-like |
cd20014 |
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the ... |
29-329 |
7.08e-32 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380667 [Multi-domain] Cd Length: 346 Bit Score: 123.11 E-value: 7.08e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtspKIGGKPVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd20014 1 KIGLLLPYSGVYAALGEDIRNGFQLYLDEHGG---KLGGRPIELVKE--DDEADPDVALQKARKLIeQDKVDVLVGPVSS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQI-AMATAPEYTQQ-GYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAyGQGLADQF 185
Cdd:cd20014 76 GVALAIRDVVEQAKVPLIvANAGANALTRAaCSPYIFRTSFSNWQLGYALGKYAAENVGKTVVTIASDYAA-GREVVAGF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKAGGATIVDREFTN-DKAVDFKAILTKLKAAKPDLVY--YGGADsqAAPMVKQMKTLGITA--PLMSGEMVKTPTF 260
Cdd:cd20014 155 KEGFEAAGGKVVGEIWTPlGTTTDFSPYLTQIAASGPDAVYafFAGAD--AVRFVKQYAEFGLKGkiPLYGPGFLTDEDV 232
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1525863046 261 LKIAGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKA--DSTDPAK 329
Cdd:cd20014 233 LPALGEAAEGIITVLHYAPTLDNPANRAFVAAYQAKYGRLPDVYAVQGYDAAQVIDAALEAVggDTSDKDI 303
|
|
| PBP1_AmiC-like |
cd06331 |
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system ... |
29-341 |
4.72e-30 |
|
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); This group includes the type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF), found in bacteria and Archaea. AmiC controls expression of the amidase operon by a ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon is induced. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380554 [Multi-domain] Cd Length: 333 Bit Score: 117.70 E-value: 4.72e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSpKIGGKPVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd06331 1 KIGLLTPLSGPASVYGRAIANGAELAVEEINAAG-GVLGRPVELVVE--DDASDPATAVAAARRLIqQDKVDAIVGPITS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIamaTAPEYT-QQGYKTTFRMMTSDTQQGSVAGTFASKDLGmKKIAIVDDRTAYGQGLADQFE 186
Cdd:cd06331 78 ATRNAVAPVAERAKVPLL---YPTFYEgGECSPYLFCFGEVPNQQLDPLIPWLMEEYG-KKFYLIGSDYVWPRTMNDAAR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 187 KAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYG--GADsqAAPMVKQMKTLGITAPLMSGEMVKTPTFL-KI 263
Cdd:cd06331 154 RVIEAHGGEVVGEEYLPLGTTDFSSVIEKIKASGADVVLSTlvGAD--AVTFLKQFAAAGLRRKVRIAALLFDENTLaGL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 264 AGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQT---YSPYAYDGAMAMLNAMKKADSTDPAKYLPVLAKTDMA 340
Cdd:cd06331 232 GAEAAEGIYSVLSYFQSLDTPENKAFVAAYRKKFGEDAPPitsLSEAAYEAVHLYAAAVEKAGSTDPEAVIAALPGVSFD 311
|
.
gi 1525863046 341 G 341
Cdd:cd06331 312 G 312
|
|
| PBP1_SBP-like |
cd19989 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
29-313 |
5.33e-27 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380644 [Multi-domain] Cd Length: 299 Bit Score: 108.52 E-value: 5.33e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVkfVLETQDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd19989 1 KIGVLTPLSGPYAALGEEARRGAQLAVEEINA-AGGILGRPV--ELVVEDTEGKPATAVQKARKLVeQDGVDFLTGAVSS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAMATAPEYT--QQGYKTTFRMMTSDTQQGSVAGTFAsKDLGMKKIAIVDDRTAYGQGLADQF 185
Cdd:cd19989 78 AVALAVAPKAAELKVPYLVTVAADDELtgENCNRYTFRVNTSDRMIARALAPWL-AENGGKKWYIVYADYAWGQSSAEAF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPD--LVYYGGAD-----SQAAP--MVKQMKTLGITAPLmsgemvk 256
Cdd:cd19989 157 KEAIEELGGEVVGTLFAPLGTTDFSSYITQISDSGADglLLALAGSDavnflKQAGQfgLGKKYKIVGGILSI------- 229
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1525863046 257 TPTFLKIAGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEevqtySPYAYDGAM 313
Cdd:cd19989 230 EPLALPALGDAAEGVYGGVRYPPTLDTPANRAFVEAYEKEYGE-----APDNFAGEA 281
|
|
| PBP1_ABC_ligand_binding-like |
cd06326 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
28-274 |
1.34e-26 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380549 [Multi-domain] Cd Length: 339 Bit Score: 108.40 E-value: 1.34e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 28 VKIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSpKIGGKPVKFVleTQDDQADPRTGTTVAQKLVD-DGIKGMLGHFN 106
Cdd:cd06326 1 IVIGQSAPLSGPLAELGREYLAGAKAYFDQVNAAG-GINGRKIRLV--TLDDGYDPARTVENTRQLIEqDKVVALFGYVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 107 SGTTIPASRIYANAGIPQIAMAT-APEYTQQGYKTTFRMMTSDTQQ-GSVAGTFASkdLGMKKIAIVDDRTAYGQGLADQ 184
Cdd:cd06326 78 TANVEAVLPLLEEAGVPLVGPLTgADSLREPGNPYVFHVRASYADEvEKIVRHLAT--LGLKRIAVVYQDDPFGKEGLAA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 185 FEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIA 264
Cdd:cd06326 156 AEAALAARGLEPVATAAVARNAADVAAAAAALAAAKPQAVVLIAAGKAAAAFIKALRAAGGAAQFYGLSVVGAAALAKAL 235
|
250
....*....|
gi 1525863046 265 GNAADGTIAS 274
Cdd:cd06326 236 GDAARGVVVS 245
|
|
| PBP1_SBP-like |
cd06328 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
29-334 |
1.93e-26 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative and gram-positive bacteria. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380551 [Multi-domain] Cd Length: 336 Bit Score: 107.77 E-value: 1.93e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd06328 1 KIGVITSLTGPLAAYGKQTERGFELGLEYATDGTMEVDGRKIEVIVK--DDQGDPDTAKAAATELIgDDGVDILVGTVSS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAM-ATAPEYTQQGY-KTTFRMMTSDTQQGSVAGTFASKDLGmKKIAIVDDRTAYGQGLADQF 185
Cdd:cd06328 79 AVALALAPVAEQNKKILIVGpAAADSITGENWnKYTFRTSRNSWQDAIAGAKALADPLG-KSVAFLAQDYAFGQDGVAAF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAG 265
Cdd:cd06328 158 KKALEAKGGKIVGEELVPVTTTDFTPYLQRILDAKPDVLFVAWAGTGALTLWQQLADQGVLDDIKVVTGGPDIATLAALG 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1525863046 266 NAADGTIASL---AGLPLEEMpgGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKA-DSTDPAKYLPVL 334
Cdd:cd06328 238 DALPGIEGLTyyyYGLPKNPV--NDWLVKAHKERYNAPPDLFTAGGFAAAQAVVRALEKAgGDTDVEKLIAAL 308
|
|
| PBP1_ABC_transporter_GPCR_C-like |
cd04509 |
Family C of G-protein coupled receptors and their close homologs, the type 1 ... |
29-272 |
2.80e-26 |
|
Family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems; This CD includes members of the family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems. The family C GPCR includes glutamate/glycine-gated ion channels such as the NMDA receptor, G-protein-coupled receptors, metabotropic glutamate, GABA-B, calcium sensing, pheromone receptors, and atrial natriuretic peptide-guanylate cyclase receptors. The glutamate receptors that form cation-selective ion channels, iGluR, can be classified into three different subgroups according to their binding-affinity for the agonists NMDA (N-methyl-D-asparate), AMPA (alpha-amino-3-dihydro-5-methyl-3-oxo-4-isoxazolepropionic acid), and kainate. L-glutamate is a major neurotransmitter in the brain of vertebrates and acts through either mGluRs or iGluRs. mGluRs subunits possess seven transmembrane segments and a large N-terminal extracellular domain. ABC-type leucine-isoleucine-valine binding protein (LIVBP) is a bacterial periplasmic binding protein that has homology with the amino-terminal domain of the glutamate-receptor ion channels (iGluRs). The extracellular regions of iGluRs are made of two PBP-like domains in tandem, a LIVBP-like domain that constitutes the N terminus (included in this model) followed by a domain related to lysine-arginine-ornithine-binding protein (LAOBP) that belongs to the type 2 periplasmic binding fold protein superfamily. The uncharacterized periplasmic components of various ABC-type transport systems are also included in this family.
Pssm-ID: 380490 Cd Length: 306 Bit Score: 107.01 E-value: 2.80e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGA----------QAHYGKDMQNGIALALEDFNATSPKIGGkpVKFVLETQDDQADPRTGTTVAQKLVDD-- 96
Cdd:cd04509 1 KVGVLFAVHGKgpsgvpcgdiVAQYGIQRFEAMEQALDDINADPNLLPN--NTLGIVIYDDCCDPKQALEQSNKFVNDli 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 97 ---------------------GIKGMLGHFNSGTTIPASRIYANAGIPQIA-MATAPEYT-QQGYKTTFRMMTSDTQQGS 153
Cdd:cd04509 79 qkdtsdvrctngeppvfvkpeGIKGVIGHLCSSVTIPVSNILELFGIPQITyAATAPELSdDRGYQLFLRVVPLDSDQAP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 154 VAGTFAsKDLGMKKIAIVDDRTAYGQGLADQFEKAAKAGGATIV--DREFTNDKAVDFKAILTKLKAAKP-DLVYYGGAD 230
Cdd:cd04509 159 AMADIV-KEKVWQYVSIVHDEGQYGEGGARAFQDGLKKGGLCIAfsDGITAGEKTKDFDRLVARLKKENNiRFVVYFGYH 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1525863046 231 SQAAPMVKQMKTLGITAP--LMSGEMVKTPTF-LKIAGNAADGTI 272
Cdd:cd04509 238 PEMGQILRAARRAGLVGKfqFMGSDGWANVSLsLNIAEESAEGLI 282
|
|
| PBP1_Nba-like |
cd06359 |
type 1 periplasmic binding component of active transport systems predicted to be involved in ... |
29-338 |
1.71e-25 |
|
type 1 periplasmic binding component of active transport systems predicted to be involved in 2-nitrobenzoic acid degradation pathway; This group includes the type 1 periplasmic binding component of active transport systems that are predicted to be involved in 2-nitrobenzoic acid degradation pathway; their substrate specificities are not well characterized.
Pssm-ID: 380582 [Multi-domain] Cd Length: 333 Bit Score: 105.03 E-value: 1.71e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtspKIGGKPVKFVLEtqDDQADPRTGTTVAQKLVD-DGIKGMLGHFNS 107
Cdd:cd06359 1 KIGFITTLSGPAAVLGQDMRDGFNLALEQLGG---KLGGLPVEVVVE--DDQLKPDVAKQAAERLIErDKVDFVTGIIFS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAMATAPEYT--QQGYKTTFRMMTSDTQQGSVAGTFASkDLGMKKIAIVDDRTAYGQGLADQF 185
Cdd:cd06359 76 NVMLAVVKPVVDSKVFYISANAGPSDLagKGCNPNFFVTSWQNDQLHEAAGKYAN-DKGYKRVYLLAPNYQAGKDALAGF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKaggATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITA--PLMSGEMVKTPTFLKI 263
Cdd:cd06359 155 KRTYK---GEVVGEIYTPLGQLDFSAELAQIRAAKPDAVFAFYPGGMGVNFVKQYAQAGLKKkiPLYTVGTLDDEDLLPA 231
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1525863046 264 AGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKA--DSTDPAKYLPVLAKTD 338
Cdd:cd06359 232 MGDAALGVLSVSQWSPDLDNPENKRFVAAFRKKYGRPPSNYAAQGYDAALLIDAAVKAVggDLSDKDALRAALRKAD 308
|
|
| PBP1_ABC_ligand_binding-like |
cd06341 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-323 |
3.67e-21 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380564 [Multi-domain] Cd Length: 340 Bit Score: 93.14 E-value: 3.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVkfVLETQDDQADPRTGTTVAQKLVD-DGIKGMLGhFNS 107
Cdd:cd06341 1 KIGLIYPDTGPGAASFSAARAGAEARFGLANA-AGGINGRKV--EYVWCDDQSDPATNLQAARQLVEdEKVFALVG-SSS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAMATAPeytQQGYKTTFRMMTSDTQQGSV--AGTFASKDLGMKKIAIVDDRTAYGQGLADQF 185
Cdd:cd06341 77 AASGSANDYLAQAGIPVVGGAGVS---VWCFRNMFSNFFSLGGGGSTttYGQYAAALGGTKAAVVVTDIPAASQQLAQQL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 186 EKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTPTFLKIAG 265
Cdd:cd06341 154 AASLRAAGVEVVGTAPYAAAAPDYTAVAQAAKAAGADAVVGVLDPDVAARVLKAARAQGLDLKVALSPSGYDPSVLAAYG 233
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1525863046 266 NAADGTIASLAGLPLEE-MPGGKTYAD---KYKKRFGEEVQTYSPYAYDGAMAMLNAMKKAD 323
Cdd:cd06341 234 AALAGVSVASTFLPFEAdTPAVKAYRAamaKYAPELQDPLQQFALSGYIAADLFVRGLEAAG 295
|
|
| PBP1_YraM_LppC_lipoprotein-like |
cd06339 |
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup ... |
29-318 |
7.88e-20 |
|
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).
Pssm-ID: 380562 [Multi-domain] Cd Length: 331 Bit Score: 89.25 E-value: 7.88e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSPKIggkpvKFVletqdDQADPRTGTTVAQKLVDDGIKGMLGHFNSG 108
Cdd:cd06339 1 RIALLLPLSGPYAAAGQAIRDGIELALFDAGGSRPEL-----RVY-----DTGGPEGAAAAYQQAVAEGADLIIGPLLKS 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 109 TTIPASRIYANAGIPQIAMATAPEYTQQGYktTFRMMTSDTQQGSVAGTFASKDlGMKKIAIVDDRTAYGQGLADQFEKA 188
Cdd:cd06339 71 SVAALAAAAQALGVPVLALNNDESATAGPG--LFQFGLSPEDEARQAARYAVQQ-GLRRFAVLAPDNAYGQRVANAFREA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 189 AKAGGATIVDREFTNDKAVDFKAILTKLKAA----------------------KPDLVYYGGADSQAAPMVKQMKTLGIT 246
Cdd:cd06339 148 WQALGGTVVAVESYDPDETDFSAAIRRLLGVdqsearirqlgellefeprrrqDFDAIFLPAGPEQARLIAPQLAFYGAG 227
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1525863046 247 -APLMSGEMVKTPTFLKIAGNAADGTIASlaglpleEMP---GGKTYADKYKKRFGEEVQTYSPYAYDgAMAMLNA 318
Cdd:cd06339 228 dVPLLGTSLWYSGKLNLLRDPDLNGAWFA-------DPPwllSPRAFPLRYRLAYGWPPPRLAALGYD-AYRLAAR 295
|
|
| ANF_receptor |
pfam01094 |
Receptor family ligand binding region; This family includes extracellular ligand binding ... |
47-358 |
1.64e-19 |
|
Receptor family ligand binding region; This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.
Pssm-ID: 460062 [Multi-domain] Cd Length: 347 Bit Score: 88.60 E-value: 1.64e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 47 MQNGIALALEDFNATSPKIGGkpVKFVLETQDDQADPRTGTTVAQKLVDDGIKGMLGHFNSGTTIPASRIYANAGIPQIA 126
Cdd:pfam01094 2 VLLAVRLAVEDINADPGLLPG--TKLEYIILDTCCDPSLALAAALDLLKGEVVAIIGPSCSSVASAVASLANEWKVPLIS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 127 -MATAPEYT-QQGYKTTFRMMTSDTQQGSVAGTFAsKDLGMKKIAIVDDRTAYGQGLADQFEKAAKAGGATIVDREFTnD 204
Cdd:pfam01094 80 yGSTSPALSdLNRYPTFLRTTPSDTSQADAIVDIL-KHFGWKRVALIYSDDDYGESGLQALEDALRERGIRVAYKAVI-P 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 205 KAVDFKAI---LTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAP---------LMSGEMVKTPTFLKIAGNA----- 267
Cdd:pfam01094 158 PAQDDDEIarkLLKEVKSRARVIVVCCSSETARRLLKAARELGMMGEgyvwiatdgLTTSLVILNPSTLEAAGGVlgfrl 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 268 ADGTIASLAGLPLEEMPGGKTYADKYkkrfGEEVQTYSPYAYDGAMAMLNAMKKADSTDP--------------AKYLPV 333
Cdd:pfam01094 238 HPPDSPEFSEFFWEKLSDEKELYENL----GGLPVSYGALAYDAVYLLAHALHNLLRDDKpgracgalgpwnggQKLLRY 313
|
330 340
....*....|....*....|....*
gi 1525863046 334 LAKTDMAGVTsSHVAYDAKGDLKNG 358
Cdd:pfam01094 314 LKNVNFTGLT-GNVQFDENGDRINP 337
|
|
| PBP1_RPA0985_benzoate-like |
cd20013 |
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the ... |
29-322 |
4.19e-19 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0985 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0985 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380666 [Multi-domain] Cd Length: 356 Bit Score: 87.31 E-value: 4.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFnatSPKIGGKPVKFVLetQDDQA-DPRTGTTVAQKL-VDDGIKGMLGHFN 106
Cdd:cd20013 1 KVGVIGPFSGPFADYGKQFDRGIDLYLKLH---GDKVGGRKVEVIY--RDDGGpNPAVAKRLAQELiVRDKVQILIGFGF 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 107 SGTTIPASRIYANAGIPQIAM-ATAPEYTQqgyKTTFRMMTSDT--QQGSVAGTFASKDlGMKKIAIVDDRTAYGQGLAD 183
Cdd:cd20013 76 TPNALAVAPVATEAKTPTVIMnAATSSITR---KSPYFVRTSFTmwQVAYPMGKWAAKN-GIKKAYTAVADYAPGHDAET 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 184 QFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYY---GGADSQAapMVKQMKTLGITAP---LMSGEMVKT 257
Cdd:cd20013 152 AFKKAFEAAGGKIVGSIRVPLATPDFAPFMQRIKDAKPDAVFVfvpAGAPSIG--FLKAYAERGLKEAgikLLGTGDATD 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1525863046 258 PTFLKIAGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQ--TYSPYAYDGaMAMLNAMKKA 322
Cdd:cd20013 230 DDDLPAMGDAALGLITAGHYSAALDSPENKAFVAAYQKAYGPDARpdFMAVAAYDG-MALIYKMIKA 295
|
|
| PBP1_ABC_ligand_binding-like |
cd06334 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-340 |
8.58e-19 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380557 [Multi-domain] Cd Length: 360 Bit Score: 86.53 E-value: 8.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSpKIGGKpvKFVLETQDDQADPRTGTTVAQKLVD-DGIKGMLGHfns 107
Cdd:cd06334 1 KIGLLTDLTGPTADVGKPYAQGVRDYLNYVNEEG-GINGV--KIELEECDTGYKVPRAVACYKRLKAqDGVVAILGW--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIP---ASRIyANAGIPQIAMATAPEYTQQGYKT--TFRMMTSDTQQGSVAGTFASKDLGM----KKIAIVDDRTAYG 178
Cdd:cd06334 75 GTGDTealAPRV-AKDKIPYISASYGRSLADDGKVFpyNFFVGATYSSQARALLKYIAQEWGGklkgPKVAFVYHDSPFG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 179 QGLADQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLM-----SGE 253
Cdd:cd06334 154 REPIPALKAYAKELGFEVVAEQVPSPGALDATAQWLRIRRAGPDYVIIQGTGGSVAVIIKDAKRLGLKTKFIgniwgGDE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 254 MVktptfLKIAGNAADGTIASLAGLPLEEMPGGKT----YADKYKKRFGEEVQTySPYAYDGAMAMLN--AMKKADSTDP 327
Cdd:cd06334 234 DL-----IKLAGDAAEGYVGVSPFAFGTDDPPGKEiveeVAKKGKGDGPEEVGT-VYYNRGWATAMLAveAIRRADKAGG 307
|
330
....*....|...
gi 1525863046 328 AKYLPVLAKTDMA 340
Cdd:cd06334 308 GTGLGNKLKAGLE 320
|
|
| PBP1_SBP-like |
cd20378 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
29-343 |
2.05e-18 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380668 [Multi-domain] Cd Length: 357 Bit Score: 85.47 E-value: 2.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSpkigGKPVKFVleTQDDQADPRTGTTVAQKLVD-DGIKGMLGHFNS 107
Cdd:cd20378 1 TLGGLVSMSGAFAAAGKLADRGMRLAVEEYGGAL----GRPLKYI--TRDTEGKPGTGVRKVQEAIAqDGARFFIGGTLS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAMATAPEYT-QQGYKTTFRMmtSDTQQGSVAGT---FASKDLGMKKIAIVDDRTAYGQGLAD 183
Cdd:cd20378 75 SVALAVSEEAEKAGGVYITSGGADEITgSRCNRSTFRW--SVPTYGAIRQTvrpVIKAMPKAKRWYTITPQYVFGESLLK 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 184 QFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLG------ITAPLMSGemvkT 257
Cdd:cd20378 153 NAKEVLKEKGIEHVGNSYHSLGEREFSGYLTKAMAARPDVLLILNFGSQAVDALRQAVSFGlkrkmkILVAWSSG----L 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 258 PTFLKIAGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEeVQTYSP-YAYDGAMAMLNAMKKADSTDPAKYLPVLAK 336
Cdd:cd20378 229 DQFQELGPDICEGVYFGAQYWHDVDTPANKALVKVYQAKFKE-TPSYALaAGYACTRMLLDAIDKAGSTDPAAVIKALEG 307
|
....*..
gi 1525863046 337 TDMAGVT 343
Cdd:cd20378 308 LKYDGIT 314
|
|
| PBP1_ABC_ligand_binding-like |
cd19978 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
28-324 |
2.38e-18 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380633 [Multi-domain] Cd Length: 341 Bit Score: 84.93 E-value: 2.38e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 28 VKIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVleTQDDQADPRTGTTVAQKLV-DDGIKGMLGHFN 106
Cdd:cd19978 1 IRLGMSAALSGPAAELGNEMKRGIEAAFNEVNA-QGGVNGRKIKLI--ALDDGYEPDRTVKNTKKLIeEDKVFALIGYVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 107 SGTTIPASRIYANAGIPQIAMAT-APEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIV--DDrtAYGQGLAD 183
Cdd:cd19978 78 TPTALAALPLANEKKIPLFGPFTgAEFLRTPFLPYVFNLRASYADETEALVDYLVKTLGPKRIAIFyqND--AFGLAGLE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 184 QFEKAAKAGGATIV-----DREftndkAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMSGEMVKTP 258
Cdd:cd19978 156 GAKKALKKRGLTPVaegsyTRN-----TLDVEEALAKILKAKPEAIILVGTYAPAAEFIRLARAAGLNPLFANVSFVGSE 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1525863046 259 TFLKIAGNAADGTIASLAgLPL---EEMPGGKTYADKYKKRFGEEvqTYSPYAYDG---AMAMLNAMKKADS 324
Cdd:cd19978 231 ALALELGDYGEGVIVSQV-VPDpndSSLPIVKEYREAMKKYGPNA--PPDFVSLEGylaARLLVEALKKAGP 299
|
|
| PBP1_SBP-like |
cd19987 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
29-329 |
5.95e-18 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380642 [Multi-domain] Cd Length: 353 Bit Score: 83.92 E-value: 5.95e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNA-------TSPKIG----GKPVKFVleTQDDQADPRTGTTVAQKLVD-D 96
Cdd:cd19987 1 TIGLNVPLSGPYAPQGEDQRRGFELAVDHLNNggglvdkDSRLSGdgilGKKVELV--TADTETKADTAVDNAKRLIEqD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 97 GIKGMLGHFNSGTTIPASRIYANAGIPQIA-MATAPEYT-QQGYKTTFRMMTSDTQQGSVAGTFASKDLG--MKKIAIVD 172
Cdd:cd19987 79 GAVMITGGSSSAVAVAAQKLAQKEGVLYFAgLSHSNDTTgKDCHRYGFRECFNAHMSAKALAPYLVEKFGkdRKYFYLTA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 173 DrTAYGQGLADQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPD---LVYYGGADSQAAPMVKQMKTLG---IT 246
Cdd:cd19987 159 D-YTWGHSTEQSMREYTEAHGWKTVGNPATPLGETDFSAALLNAADSGADvlvLVLFGRDMVNALKQAKQFGLLKkmdIV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 247 APLMSGEMVKTPtflkiAGNAADGTIASLA---GLPlEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKAD 323
Cdd:cd19987 238 VPLLTAFMAESV-----GPEIMEGVLGTVNwhwSLP-DDYSYAFGKAEAFEKEYGAYPSQAAASAYVQVLQYAAAVERAG 311
|
....*.
gi 1525863046 324 STDPAK 329
Cdd:cd19987 312 SFDPPA 317
|
|
| PBP1_SBP-like |
cd06329 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
29-329 |
2.03e-16 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380552 [Multi-domain] Cd Length: 343 Bit Score: 79.63 E-value: 2.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtspKIGGKPVKFVLETQDDQADPRTGTTVAQKLVDDGIKGMLGHFNSG 108
Cdd:cd06329 1 KIAFIDPLSGPFASVGEIYLKGLQFAIEEINA---GGGLLGRKIELVPFDNKGSPQEALIQLKKAIDQGIRFVLQGNSSA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 109 TTI-------------PASR-IYANAGipqiamATAPEYTqqGYKTTFRMMTSDTQQGSVAGTFA---SKDLGMKKIAIV 171
Cdd:cd06329 78 VAGalidaiekhnqrnPDKRvLFLNYG------AEAPELT--GAKCSFWHFRFDANADMKMAALAdymKKDGSIKKVYLI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 172 DDRTAYGQGLADQFEKAAKA--GGATIVDREFTN-DKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAP 248
Cdd:cd06329 150 NQDYSFGRDVAAAAKKNLKKkrPDIEIVGEDLHPlGKVKDFSPYIAKIKASGADTVITGNWGNDLTLLMKAARDSGLKAP 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 249 LMSGEMVKtPTFLKIAGNAADGTI-ASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDP 327
Cdd:cd06329 230 FYTYYADG-PGAPAAIGEAGVGRLvAVAYWHPNPKTPELEKFAEAFRAKYGRYPDFNIGRTYMGVEMLAAAIKKAGSTDP 308
|
..
gi 1525863046 328 AK 329
Cdd:cd06329 309 EK 310
|
|
| PBP1_amide_urea_BP-like |
cd06356 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
29-329 |
3.06e-16 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the type 1 periplasmic-binding proteins that are predicted to have a function similar to that of an active transport system for short chain amides and/or urea in bacteria and Archaea, by sequence comparison and phylogenetic analysis.
Pssm-ID: 380579 [Multi-domain] Cd Length: 334 Bit Score: 78.88 E-value: 3.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVleTQDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd06356 1 KIGSIFDLSGGLNIYGKPMVHAMKLAVEEINA-AGGLLGRQIELV--AYDTQSDMQKYTQYAQQLIlRDKVDVVFGGITS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 gttipASR-----IYANAGIPQIamatapeYTQQGY-----KTTFRMMTSDTQQGSVAGTFASKDLGmKKIAIVDDRTAY 177
Cdd:cd06356 78 -----ASReairpILRRNKILYF-------YNTQYEggvcdKNTFCTGSTPEQQVSPLIEWAIKKYG-KKVYIIAADYNF 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 178 GQGLADQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYY---GGADSQ------AAPMVKQMKtlgitap 248
Cdd:cd06356 145 GQISADWVKKYAKKNGGEVVGEEFFPLDVTDFGPTIQKIQAAKPDFVVSllvGGNHISfyrqwaAAGLKKKIP------- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 249 lmsgemVKTPTFlkIAGN--------AADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSP--YAYDGAMAMLNA 318
Cdd:cd06356 218 ------IVSTVF--GAGNehkvlsppELEGMYVSYSYFEELDTPANKAFVAKWRAKYGDEPYINQEavGVYNAVYLWAEA 289
|
330
....*....|.
gi 1525863046 319 MKKADSTDPAK 329
Cdd:cd06356 290 VEKAGSTEREA 300
|
|
| PBP1_ABC_ligand_binding-like |
cd19979 |
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes ... |
29-329 |
1.22e-14 |
|
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380634 [Multi-domain] Cd Length: 350 Bit Score: 74.18 E-value: 1.22e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKfvLETQDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd19979 1 VIGLDADLSGGSAASGEAIKRGIQLAIDEINA-AGGLLGRKLE--LVAKDHRGNPARGVDNLREFAaDPDVLAVFGGLHS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 gTTIPASRIYANA-GIPQ-IAMATAPEYTQQGYKT--TFRMMTSDTQQGSVAGTFASKDlGMKKIAIVDDRTAYGQGLAD 183
Cdd:cd19979 78 -PVLLAELDFIHElKIPYlVPWAAATPITRNGYSPnyIFRLSVDDSLAGPFLVEYALKK-GCKRPALLLENTGWGRSNLK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 184 QFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAPLMS--Gemvktptfl 261
Cdd:cd19979 156 AMTKALAKKGLQPVGVEWFNWGDTDAKPQLRALKAAGADAILLVANAPEGAAIVKALAALPERLPIIShwG--------- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 262 kIAGN---AADGTIASLAGL---------PLEEMPGGKTYADKYKKRFGEEVQT---YSP----YAYDGAMAMLNAMKKA 322
Cdd:cd19979 227 -ITGGdfpELPREALSKIDLrfiqtfsffDANQSPRGKQVLARYKRRYPVEDPEsdiPAPvgfaHAYDLTHLLALAIEQA 305
|
....*..
gi 1525863046 323 DSTDPAK 329
Cdd:cd19979 306 GSTDRAA 312
|
|
| PBP1_ABC_ligand_binding-like |
cd06337 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-339 |
9.33e-13 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380560 [Multi-domain] Cd Length: 354 Bit Score: 68.48 E-value: 9.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHYGKDMQNGIALALEDFNATSPKIGGKPVKFVLETQDDQADPRTGTTVAQKLV-DDGIKGMLGHFNS 107
Cdd:cd06337 1 KIGRVSPLTGPLAAFGEADPWVLEQIREAFADGGIKVGGKKYPVEIVVRDSQSDPNRAGEAARDLIlRDKVDLMLASGTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIaMATAPEYT---------QQGYKTTFRMMTSdtqqgsvAGTFASKDLGM-------KKIAIV 171
Cdd:cd06337 81 DTVNPVADQCEANGVPCI-STDAPWQAwffgrggdpAKGFKWTFHFFWG-------LEDIAANFLGMwdqvptnKVVGLL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 172 DDRTAYGQGLADQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAK----------PDLVYYGGADSQAAPMVKqMK 241
Cdd:cd06337 153 WPNDPDGTAFADAFLGLPAAAGYTLVDPGRFPPGTDDFSSIINAFKKAGveivtgvmipPDFATFWRQAAQQGFKPK-VV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 242 TLGItAPLMsgemvktPTFLKIAGNAADGtIASLAG----LPLEEMPGGKT---YADKYKKRFGEEVQTYSPYAYDGAMA 314
Cdd:cd06337 232 TIGK-ALLF-------PSAVAALGDLGDG-LSTEVWwspaHPFKSSLTGQTaaeLADAYEKATGKQWTQPLGYAHALFEV 302
|
330 340
....*....|....*....|....*
gi 1525863046 315 MLNAMKKADSTDPAKYLPVLAKTDM 339
Cdd:cd06337 303 AVDALKRAGSPDDEAVRAALADTDL 327
|
|
| PBP1_SBP-like |
cd06327 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
29-336 |
6.11e-12 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380550 [Multi-domain] Cd Length: 336 Bit Score: 66.06 E-value: 6.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQAHY-GKDMQNGIALALEDFNatsPKIGGKPVKFVleTQDDQADPRTGTTVAQKLVD-DGIKGMLGHFN 106
Cdd:cd06327 1 RIGVLTDLSGVYADLsGPGSVEAAKMAVEDFG---GKVLGRPIEVV--SADHQNKPDVASAIAREWYDrDGVDAIVDVPN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 107 SGTTIPASRIYANAGIpqIAMATAPEYTQQGYK----TTFRMMTSDTQQGSVAGTFASKDLGmKKIAIVDDRTAYGQGLA 182
Cdd:cd06327 76 SAVALAVQKLAKEKKK--IAIVTGAGSSDLTGKacspYGVHWAYDTYALARGTVKALVKQGG-KSWFFITADYAFGHSLE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 183 DQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYY--GGADSQAApmVKQMKTLGITAPLMsgemvktptf 260
Cdd:cd06327 153 ADATAAVKAAGGKVVGSVRHPLGTTDFSSFLLQAQASGADVIALanAGADLVNA--VKQAREFGLTDGGQ---------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 261 lKIAGNAAdgTIASLAGLPLEEM--------------PGGKTYADKYKKRFGE---EVQTyspYAYDGAMAMLNAMKKAD 323
Cdd:cd06327 221 -KLAALLL--FITDIHALGLDAAqglylttafywdrdDATRAWAKRFFARTGKmptMLQA---GVYSAVLHYLKAVKAAG 294
|
330
....*....|...
gi 1525863046 324 STDPAKylpVLAK 336
Cdd:cd06327 295 TDDADA---VVAK 304
|
|
| PBP1_GPCR_family_C-like |
cd06350 |
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory ... |
91-246 |
6.86e-12 |
|
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate; categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (m; Ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate and are categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs). The metabotropic glutamate receptors (mGluR) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. The mGluRs are coupled to G proteins and are thus distinct from the iGluRs which internally contain ligand-gated ion channels. The mGluR structure is divided into three regions: the extracellular region, the seven-spanning transmembrane region and the cytoplasmic region. The extracellular region is further divided into the ligand-binding domain (LBD) and the cysteine-rich domain. The LBD has sequence similarity to the LIVBP, which is a bacterial periplasmic protein (PBP), as well as to the extracellular region of both iGluR and the gamma-aminobutyric acid (GABA)b receptor. iGluRs are divided into three main subtypes based on pharmacological profile: NMDA, AMPA, and kainate receptors. All family C GPCRs have a large extracellular N terminus that contain a domain with homology to bacterial periplasmic amino acid-binding proteins.
Pssm-ID: 380573 Cd Length: 350 Bit Score: 66.16 E-value: 6.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 91 QKLVDDGIKGMLGHFNSGTTIPASRIYANAGIPQIA-MATAPEYT-QQGYKTTFRMMTSDTQQGS-VAGTFasKDLGMKK 167
Cdd:cd06350 88 QNIGPPNIVAVIGAASSSVSIAVANLLGLFKIPQISyASTSPELSdKIRYPYFLRTVPSDTLQAKaIADLL--KHFNWNY 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 168 IAIVDDRTAYGQGLADQFEKAAKAGGATI-VDREFT-NDKAVDFKAILTKLKAA-KPDLVYYGGADSQAAPMVKQMKTLG 244
Cdd:cd06350 166 VSTVYSDDDYGRSGIEAFEREAKERGICIaQTIVIPeNSTEDEIKRIIDKLKSSpNAKVVVLFLTESDARELLKEAKRRN 245
|
..
gi 1525863046 245 IT 246
Cdd:cd06350 246 LT 247
|
|
| PBP1_AmiC |
cd06357 |
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding ... |
37-340 |
8.32e-10 |
|
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family; This group includes the periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family. AmiC controls expression of the amidase operon by the ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon are induced.
Pssm-ID: 380580 [Multi-domain] Cd Length: 357 Bit Score: 59.51 E-value: 8.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 37 TGAQAHYGKDMQNGIALALEDFNAtSPKIGGKPVKFVLEtqDDQADPRTGTTVAQKLV-DDGIKgmlgHFNSGTTiPASR 115
Cdd:cd06357 9 TGVTAIIEQSMLNGALLAIEEINA-AGGVNGRPIEPVVY--DPASDPDRYRELAERLLlEDGVR----HIFGCYT-SASR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 116 iyaNAGIPQIAMATAPE-YTQQ--GYKTTFRMM---TSDTQQGSVAGTFASKDLGmKKIAIVDDRTAYGQGLADQFEKAA 189
Cdd:cd06357 81 ---KAVLPVVERHNALLwYPTPyeGFEYSPNVIytgAVPNQHLLPLARYLLAHFG-KRVFLVGSNYVYPWESNRVARELI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 190 KAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITA---PLMSgeMVKTPTFLK-IAG 265
Cdd:cd06357 157 EASGGEVVGERYVPLGDTDFAEIIEEIKSLKPDVVFSTLVGDSIYAFYRAYAEAGLDPadmPIAS--LTTSEAEVAaIGA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 266 NAADGTIASL---AGLPLEEmpgGKTYADKYKKRFGEEVQTYSPY--AYDGAMAMLNAMKKADSTDPAKYLPVLAKTDMA 340
Cdd:cd06357 235 EAAAGHYTSApyfQSIDTPE---NRAFVEAYRARFGDDAVTSAVAeaAYFQVHLLARAIERAGSDDPEAIRAALYGQEFD 311
|
|
| PBP1_GABAb_receptor |
cd06366 |
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for ... |
30-354 |
2.20e-08 |
|
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA); Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380589 [Multi-domain] Cd Length: 404 Bit Score: 55.33 E-value: 2.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 30 IGYAGPMTGAQAHY-GKDMQNGIALALEDFNaTSPKIGgKPVKFVLETQDDQADPRTGTTVAQKLVDDG--IKGMLGHFN 106
Cdd:cd06366 2 IGGLFPLSGSKGWWgGAGILPAAEMALEHIN-NRSDIL-PGYNLELIWNDTQCDPGLGLKALYDLLYTPppKVMLLGPGC 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 107 SGTTIP---ASRIYAnagIPQIAM-ATAPEYT-QQGYKTTFRMMTSDTQQGSVAGTFAsKDLGMKKIAIVDDRTAYGQGL 181
Cdd:cd06366 80 SSVTEPvaeASKYWN---LVQLSYaATSPALSdRKRYPYFFRTVPSDTAFNPARIALL-KHFGWKRVATIYQNDEVFSST 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 182 ADQFEKAAKAGGATIVDRE-FTNDkavDFKAILTKLKAAKPDLVYYGGADSQAAPMVKQMKTLGITAP----LMSGEMvk 256
Cdd:cd06366 156 AEDLEELLEEANITIVATEsFSSE---DPTDQLENLKEKDARIIIGLFYEDAARKVFCEAYKLGMYGPkyvwILPGWY-- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 257 TPTFLKIAGN-----------AADGTIaSLAGLPL----EEMPGGKTyADKYKKRFGEEVQT-------YSPYAYDG--- 311
Cdd:cd06366 231 DDNWWDVPDNdvnctpeqmleALEGHF-STELLPLnpdnTKTISGLT-AQEFLKEYLERLSNsnytgspYAPFAYDAvwa 308
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1525863046 312 -AMAMLNAMKKADST----DPAKY---------LPVLAKTDMAGVtSSHVAYDAKGD 354
Cdd:cd06366 309 iALALNKTIEKLAEYnktlEDFTYndkemadlfLEAMNSTSFEGV-SGPVSFDSKGD 364
|
|
| PBP1_FmdD-like |
cd06355 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
189-341 |
3.19e-08 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF), found in Methylophilus methylotrophus, and its homologs from other bacteria. FmdD, a type 1 periplasmic binding protein, is induced by short-chain amides and urea and repressed by excess ammonia, while FmdE and FmdF are hydrophobic transmembrane proteins. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380578 [Multi-domain] Cd Length: 347 Bit Score: 54.89 E-value: 3.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 189 AKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVYYG-GADSQAApMVKQMKTLGITA---PLMS---GEmvktPTFL 261
Cdd:cd06355 156 LKALGGEVVGEEYVPLGGTDFDAIVAKIKAFKPDVIVNTlNGDSNIA-FFKQLAAAGITAsdlPVLSfsvSE----AELR 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 262 KIAGNAADGTIASLAGLPLEEMPGGKTYADKYKKRFGEEVQTYSPY--AYDGAMAMLNAMKKADSTDPAKYLPVLAKTDM 339
Cdd:cd06355 231 AIGPEELAGHYAAWNYFQSLDTPENQAFVEAFKAKYGADRVTSDPMeaAYLGVYLWAQAVEKAGSFDPDAVRAALKGQSF 310
|
..
gi 1525863046 340 AG 341
Cdd:cd06355 311 EA 312
|
|
| PBP1_GABAb_receptor_plant |
cd19990 |
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close ... |
44-343 |
2.43e-06 |
|
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants; This group includes the ligand-binding domain of Arabidopsis thaliana glutamate receptors, which have sequence similarity with animal ionotropic glutamate receptor and its close homologs in other plants. The ligand-binding domain of GABAb receptors are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380645 [Multi-domain] Cd Length: 373 Bit Score: 49.15 E-value: 2.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 44 GKDMQNGIALALEDFNATSPkigGKPVKFVLETQDDQADPRTGTTVAQKLV-DDGIKGMLGHFNSGTTIPASRIYANAGI 122
Cdd:cd19990 13 GKEAKVAIEMAVSDFNSDSS---SYGTKLVLHVRDSKGDPLQAASAALDLIkNKKVEAIIGPQTSEEASFVAELGNKAQV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 123 PQIAM-ATAPEYTQQGYKTTFRMMTSDTQQ-GSVAGTFASkdLGMKKIAIVDDRTAYGQGLADQFEKAAKAGGATIVDR- 199
Cdd:cd19990 90 PIISFsATSPTLSSLRWPFFIRMTHNDSSQmKAIAAIVQS--YGWRRVVLIYEDDDYGSGIIPYLSDALQEVGSRIEYRv 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 200 ---EFTNDKAVDfkAILTKLKAAK---------PDLvyyggadsqAAPMVKQMKTLGitapLMSGEMVktptflKIAGNA 267
Cdd:cd19990 168 alpPSSPEDSIE--EELIKLKSMQsrvfvvhmsSLL---------ASRLFQEAKKLG----MMEKGYV------WIVTDG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 268 ADGTIASLAGLPLEEMPG--G-KTY----------ADKYKKRFGEE--------VQTYSPYAYDGAMAMLNAMKKADSTD 326
Cdd:cd19990 227 ITNLLDSLDSSTISSMQGviGiKTYipessefqdfKARFRKKFRSEypeeenaePNIYALRAYDAIWALAHAVEKLNSSG 306
|
330 340
....*....|....*....|....*
gi 1525863046 327 PA--------KYLPVLAKTDMAGVT 343
Cdd:cd19990 307 GNisvsdsgkKLLEEILSTKFKGLS 331
|
|
| RbsB |
COG1879 |
ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH ... |
6-246 |
3.21e-05 |
|
ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain [Carbohydrate transport and metabolism];
Pssm-ID: 441483 [Multi-domain] Cd Length: 307 Bit Score: 45.30 E-value: 3.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 6 KKLAGATFVAVMSLA-----------GTAHADDVKIGYAGPMTGAQahYGKDMQNGIALALEDFNATspkiggkpvkfvL 74
Cdd:COG1879 1 KRLALLAAVLALALAlaacgsaaaeaAAAAAKGKTIGFVVKTLGNP--FFVAVRKGAEAAAKELGVE------------L 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 75 ETQDDQADPRTGTTVAQKLVDDGIKG-MLGHFNSGTTIPASRIYANAGIPQIAMATAPEYTQQgyktTFRMMTSDTQQGS 153
Cdd:COG1879 67 IVVDAEGDAAKQISQIEDLIAQGVDAiIVSPVDPDALAPALKKAKAAGIPVVTVDSDVDGSDR----VAYVGSDNYAAGR 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 154 VAGTFASKDLGMK-KIAIVD-DRTAYGQGL-ADQFEKA-AKAGGATIVDREFTNDKAVDFKAILTKLKAAKPDLVY-YGG 228
Cdd:COG1879 143 LAAEYLAKALGGKgKVAILTgSPGAPAANErTDGFKEAlKEYPGIKVVAEQYADWDREKALEVMEDLLQAHPDIDGiFAA 222
|
250
....*....|....*...
gi 1525863046 229 ADSQAAPMVKQMKTLGIT 246
Cdd:COG1879 223 NDGMALGAAQALKAAGRK 240
|
|
| PBP1_mGluR |
cd06362 |
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of ... |
98-220 |
6.67e-03 |
|
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of the metabotropic glutamate receptors (mGluR), which are members of the family C of G-protein-coupled receptors that transduce extracellular signals into G-protein activation and ultimately into cellular responses. mGluRs bind to glutamate and function as an excitatory neurotransmitter; they are involved in learning, memory, anxiety, and the perception of pain. Eight subtypes of mGluRs have been cloned so far, and are classified into three groups according to their sequence similarities, transduction mechanisms, and pharmacological profiles. Group I is composed of mGlu1R and mGlu5R that both stimulate PLC hydrolysis. Group II includes mGlu2R and mGlu3R, which inhibit adenylyl cyclase, as do mGlu4R, mGlu6R, mGlu7R, and mGlu8R, which form group III.
Pssm-ID: 380585 [Multi-domain] Cd Length: 460 Bit Score: 38.43 E-value: 6.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 98 IKGMLGHFNSGTTIPAS---RIYanaGIPQIA-MATAPEYTQQG-YKTTFRMMTSDTQQgsvAGTFAS--KDLGMKKIAI 170
Cdd:cd06362 108 VVGVIGAESSSVSIQVAnllRLF---KIPQISyASTSDELSDKErYPYFLRTVPSDSFQ---AKAIVDilLHFNWTYVSV 181
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1525863046 171 VDDRTAYGQGLADQFEKAAKA-----GGATIVDREFTNDkavDFKAILTKLKAAK 220
Cdd:cd06362 182 VYSEGSYGEEGYKAFKKLARKagiciAESERISQDSDEK---DYDDVIQKLLQKK 233
|
|
| PBP1_ABC_sugar_binding-like |
cd01536 |
periplasmic sugar-binding domain of active transport systems that are members of the type 1 ... |
29-246 |
7.11e-03 |
|
periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily; Periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily. The members of this family function as the primary receptors for chemotaxis and transport of many sugar based solutes in bacteria and archaea. The sugar binding domain is also homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR. Moreover, this periplasmic binding domain, also known as Venus flytrap domain, undergoes transition from an open to a closed conformational state upon the binding of ligands such as lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. This family also includes the periplasmic binding domain of autoinducer-2 (AI-2) receptors such as LsrB and LuxP which are highly homologous to periplasmic pentose/hexose sugar-binding proteins.
Pssm-ID: 380478 [Multi-domain] Cd Length: 268 Bit Score: 37.93 E-value: 7.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 29 KIGYAGPMTGAQahYGKDMQNGIALALEDFNATspkiggkpvkfvLETQDDQADPRTGTTVAQKLVDDGIKG-MLGHFNS 107
Cdd:cd01536 1 KIGVVVKDLTNP--FWVAVKKGAEAAAKELGVE------------LVVLDAQGDVAKQISQIEDLIAQGVDAiIIAPVDS 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525863046 108 GTTIPASRIYANAGIPQIAMATAPEytQQGYKTTFrMMTSDTQQGSVAGTFASKDLGMK-KIAIV---------DDRTAY 177
Cdd:cd01536 67 EALVPAVKKANAAGIPVVAVDTDID--GGGDVVAF-VGTDNYEAGKLAGEYLAEALGGKgKVAILegppgsstaIDRTKG 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1525863046 178 gqgladqFEKA-AKAGGATIVDREFTN---DKAVD-FKAILTklkaAKPDL-VYYGGADSQAAPMVKQMKTLGIT 246
Cdd:cd01536 144 -------FKEAlKKYPDIEIVAEQPANwdrAKALTvTENLLQ----ANPDIdAVFAANDDMALGAAEALKAAGRT 207
|
|
| |
