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Conserved domains on  [gi|1528361661|ref|WP_124830547|]
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MULTISPECIES: GMC family oxidoreductase [Burkholderia]

Protein Classification

GMC family oxidoreductase( domain architecture ID 11455227)

GMC (glucose-methanol-choline) family oxidoreductase is a flavoprotein that catalyzes the oxidation of an alcohol moiety to the corresponding aldehyde with the concomitant reduction of flavin adenine dinucleotide (FAD)

EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660
PubMed:  23578136|1542121
SCOP:  3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 1-540 0e+00

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 695.81  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661   1 MTYDYIIVGAGSAGCILANRLSESGRHSVLLLEAGEQDASFWFKVPVGFTKTYYNRRYNWMYYSEPEAQLDGRSLYCPRG 80
Cdd:COG2303     3 EEYDYVIVGAGSAGCVLANRLSEDAGLRVLLLEAGGRDDDPLIRMPAGYAKLLGNPRYDWRYETEPQPGLNGRRLYWPRG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  81 KVVGGSGSINAMVYVRGQRSDYDDWAAAGNAGWAYDDVLPYFRKLETHAAGATDpqHHGTSGPIHITSMKADvHPIVHEF 160
Cdd:COG2303    83 KVLGGSSSINGMIYVRGQPEDFDLWAQLGNQGWGYDDVLPYFKRAEDNERGADA--YHGRSGPLPVSDPPLP-NPLSDAF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 161 LKGCEQLNLPRTDDFNGARFEGAGIYDLNTKHGERCSSSFAYLRPALGRPNLTLRAGVLVRRVTFDGTRAAGVIVAGERG 240
Cdd:COG2303   160 IEAAEELGIPRADDFNGGACEGCGFCQVTCRNGARWSAARAYLPPALKRPNLTVRTGALVTRILFDGGRATGVEYRDDGE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 241 DETLSAAREVILAAGAVDTPKLLQLSGVGDPALLARHRVPLVHALPAVGRNLQDHLCVSFYFKANRPTlndEMGTLLGKV 320
Cdd:COG2303   240 EHTVRAAREVILAAGAINSPQLLLLSGIGPASHLREHGIPVVHDLPGVGRNLQDHLEVSVVFRFKEPV---TLNKSLRKA 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 321 KIGLRYLLTKRGPLAMSVNQAGGFFRGTADTHEPNLQLYFNPLSYRIPKSDRAsikPEPYSGFLIAFNPCRPTSRGTIEI 400
Cdd:COG2303   317 RIGLQYLLTRSGPLTSNVAEAGGFFRSDPGLERPDLQFHFLPLGLTPRWGKKA---LHDGHGFTAHVEQLRPESRGRVTL 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 401 ASNRAEDAAKIRINALTTQKDLDEAVQGSKVIRALMQAPALKAMTVEEISPGPQVDSDEAMRqYFREQSGSIYHLCGSCA 480
Cdd:COG2303   394 DSADPLGAPLIRPNYLSDENDRRVLVAGVRLAREIAAQPALAPYRGEEILPGPDVQSDEELA-FIRARAYTIYHPVGTCR 472

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 481 MGPDaATSVVDASLRVHGLKALRIVDASVFPNITSGNINAPTMMVAEKGADLILADALRG 540
Cdd:COG2303   473 MGTD-PDSVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTIMLAEKAADMILGDYLKN 531
 
Name Accession Description Interval E-value
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 1-540 0e+00

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 695.81  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661   1 MTYDYIIVGAGSAGCILANRLSESGRHSVLLLEAGEQDASFWFKVPVGFTKTYYNRRYNWMYYSEPEAQLDGRSLYCPRG 80
Cdd:COG2303     3 EEYDYVIVGAGSAGCVLANRLSEDAGLRVLLLEAGGRDDDPLIRMPAGYAKLLGNPRYDWRYETEPQPGLNGRRLYWPRG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  81 KVVGGSGSINAMVYVRGQRSDYDDWAAAGNAGWAYDDVLPYFRKLETHAAGATDpqHHGTSGPIHITSMKADvHPIVHEF 160
Cdd:COG2303    83 KVLGGSSSINGMIYVRGQPEDFDLWAQLGNQGWGYDDVLPYFKRAEDNERGADA--YHGRSGPLPVSDPPLP-NPLSDAF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 161 LKGCEQLNLPRTDDFNGARFEGAGIYDLNTKHGERCSSSFAYLRPALGRPNLTLRAGVLVRRVTFDGTRAAGVIVAGERG 240
Cdd:COG2303   160 IEAAEELGIPRADDFNGGACEGCGFCQVTCRNGARWSAARAYLPPALKRPNLTVRTGALVTRILFDGGRATGVEYRDDGE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 241 DETLSAAREVILAAGAVDTPKLLQLSGVGDPALLARHRVPLVHALPAVGRNLQDHLCVSFYFKANRPTlndEMGTLLGKV 320
Cdd:COG2303   240 EHTVRAAREVILAAGAINSPQLLLLSGIGPASHLREHGIPVVHDLPGVGRNLQDHLEVSVVFRFKEPV---TLNKSLRKA 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 321 KIGLRYLLTKRGPLAMSVNQAGGFFRGTADTHEPNLQLYFNPLSYRIPKSDRAsikPEPYSGFLIAFNPCRPTSRGTIEI 400
Cdd:COG2303   317 RIGLQYLLTRSGPLTSNVAEAGGFFRSDPGLERPDLQFHFLPLGLTPRWGKKA---LHDGHGFTAHVEQLRPESRGRVTL 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 401 ASNRAEDAAKIRINALTTQKDLDEAVQGSKVIRALMQAPALKAMTVEEISPGPQVDSDEAMRqYFREQSGSIYHLCGSCA 480
Cdd:COG2303   394 DSADPLGAPLIRPNYLSDENDRRVLVAGVRLAREIAAQPALAPYRGEEILPGPDVQSDEELA-FIRARAYTIYHPVGTCR 472

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 481 MGPDaATSVVDASLRVHGLKALRIVDASVFPNITSGNINAPTMMVAEKGADLILADALRG 540
Cdd:COG2303   473 MGTD-PDSVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTIMLAEKAADMILGDYLKN 531
PRK02106 PRK02106
choline dehydrogenase; Validated
 1-534 0e+00

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 585.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661   1 MTYDYIIVGAGSAGCILANRLSESGRHSVLLLEAGEQD--ASFWFKVPVGFTKTYYNRRYNWMYYSEPEAQLDGRSLYCP 78
Cdd:PRK02106    4 MEYDYIIIGAGSAGCVLANRLSEDPDVSVLLLEAGGPDyrWDFFIQMPAALAFPLQGKRYNWAYETEPEPHMNNRRMECP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  79 RGKVVGGSGSINAMVYVRGQRSDYDDWAAAGNAGW-AYDDVLPYFRKLETHAAGATDpqHHGTSGPIHITSMKADVHPIV 157
Cdd:PRK02106   84 RGKVLGGSSSINGMVYIRGNAMDYDNWAELPGLEGwSYADCLPYFKKAETRDGGEDD--YRGGDGPLSVTRGKPGTNPLF 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 158 HEFLKGCEQLNLPRTDDFNGARFEGAGIYDLNTKHGERCSSSFAYLRPALGRPNLTLRAGVLVRRVTFDGTRAAGVIVAG 237
Cdd:PRK02106  162 QAFVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTNGRRWSAARAYLDPALKRPNLTIVTHALTDRILFEGKRAVGVEYER 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 238 ERGDETLSAAREVILAAGAVDTPKLLQLSGVGDPALLARHRVPLVHALPAVGRNLQDHLCVSFYFKANRP-TLNDEMGtL 316
Cdd:PRK02106  242 GGGRETARARREVILSAGAINSPQLLQLSGIGPAEHLKELGIPVVHDLPGVGENLQDHLEVYIQYECKQPvSLYPALK-W 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 317 LGKVKIGLRYLLTKRGPLAMSVNQAGGFFRGTADTHEPNLQLYFNPLSYRipksDRASIKPEPYsGFLIAFNPCRPTSRG 396
Cdd:PRK02106  321 WNKPKIGAEWLFTGTGLGASNHFEAGGFIRSRAGVDWPNIQYHFLPVAIR----YDGSNAVKGH-GFQAHVGPMRSPSRG 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 397 TIEIASNRAEDAAKIRINALTTQKDLDEAVQGSKVIRALMQAPALKAMTVEEISPGPQVDSDEAMRQYFREQSGSIYHLC 476
Cdd:PRK02106  396 SVKLKSADPRAHPSILFNYMSTEQDWREFRDAIRLTREIMAQPALDPYRGREISPGADVQTDEEIDAFVREHAETAYHPS 475

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1528361661 477 GSCAMGPDaATSVVDASLRVHGLKALRIVDASVFPNITSGNINAPTMMVAEKGADLIL 534
Cdd:PRK02106  476 CTCKMGTD-PMAVVDPEGRVHGVEGLRVVDASIMPTITNGNLNAPTIMIAEKAADLIR 532
betA TIGR01810
choline dehydrogenase; Choline dehydrogenase catalyzes the conversion of exogenously supplied ...
 4-534 1.22e-151

choline dehydrogenase; Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli, Staphylococcus xylosus, and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified. [Cellular processes, Adaptations to atypical conditions]


Pssm-ID: 273814 [Multi-domain]  Cd Length: 532  Bit Score: 445.48  E-value: 1.22e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661   4 DYIIVGAGSAGCILANRLSESGRHSVLLLEAGEQDASFWF--KVPVGFTKTYYNRRYNWMYYSEPEAQLDGRSLYCPRGK 81
Cdd:TIGR01810   1 DYIIIGGGSAGSVLAGRLSEDVSNSVLVLEAGGSDYPWDLliQMPAALAYPAGNKRYNWIYETEPEPHMNNRRVGHARGK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  82 VVGGSGSINAMVYVRGQRSDYDDWAAAGNAGW-AYDDVLPYFRKLETHAAGATDpqHHGTSGPIHITSMKADvHPIVHEF 160
Cdd:TIGR01810  81 VLGGSSSINGMIYQRGNPMDYEKWAKPEGMESwDYADCLPYYKRLETTFGGEKP--YRGHDGPIKVRRGPAD-NPLFQAF 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 161 LKGCEQLNLPRTDDFNGARFEGAGIYDLNTKHGERCSSSFAYLRPALGRPNLTLRAGVLVRRVTFDGTRAAGVIVagERG 240
Cdd:TIGR01810 158 IEAGVEAGYNKTPDVNGFRQEGFGPMDSTVHNGRRVSAARAYLHPAMKRPNLEVQTRAFVTKINFEGNRATGVEF--KKG 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 241 D--ETLSAAREVILAAGAVDTPKLLQLSGVGDPALLARHRVPLVHALPAVGRNLQDHLCVSFYFKANRPTLNDEMGTLLG 318
Cdd:TIGR01810 236 GrkEHTEANKEVILSAGAINSPQLLQLSGIGDAEHLRELGIEPRIHLPGVGENLQDHLEVYVQHACKQPVSLYPSLNWLK 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 319 KVKIGLRYLLTKRGPLAMSVNQAGGFFRGTADTHEPNLQLYFNPLSYRIPKSDRASikpepYSGFLIAFNPCRPTSRGTI 398
Cdd:TIGR01810 316 QPFIGAQWLFGRKGAGASNHFEGGGFVRSNDDVDYPNIQYHFLPVAIRYDGTKAPK-----AHGFQVHVGPMYSNSRGHV 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 399 EIASNRAEDAAKIRINALTTQKDLDEAVQGSKVIRALMQAPALKAMTVEEISPGPQVDSDEAMRQYFREQSGSIYHLCGS 478
Cdd:TIGR01810 391 KIKSKDPFEKPEIVFNYMSHEEDWREFREAIRVTREILKQKALDPYRGGEISPGPEVQTDEEIDEFVRRHGETALHPCGT 470

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1528361661 479 CAMGP-DAATSVVDASLRVHGLKALRIVDASVFPNITSGNINAPTMMVAEKGADLIL 534
Cdd:TIGR01810 471 CKMGPaSDEMSVVDPETRVHGMEGLRVVDASIMPRITNGNLNAPVIMMGEKAADIIR 527
GMC_oxred_N pfam00732
GMC oxidoreductase; This family of proteins bind FAD as a cofactor.
 71-297 6.85e-48

GMC oxidoreductase; This family of proteins bind FAD as a cofactor.


Pssm-ID: 366272 [Multi-domain]  Cd Length: 218  Bit Score: 165.92  E-value: 6.85e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  71 DGRSLYCPRGKVVGGSGSINAMVYVRGQRSDYDD-WAAAGNAGWAYDDVLPYFRKLEthaagatdpqhhgtsGPIHITSM 149
Cdd:pfam00732  15 NGRRMILPAGSTVGGGSSVNWSACIRTPAAVLDEwASEFGLEGWGYDDYLPYMDKVE---------------GPLGVTTK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 150 KADVHPIVHEFLKGCEQLNLP---RTDDFNGARFEGAGIYDlnTKHGERCSSSFAYLRPALGRpNLTLRAGVLVRRVTFD 226
Cdd:pfam00732  80 GIEESPLNQALLKAAEELGYPveaVPRNSNGCHYCGFCGLG--CPTGAKQSTARTWLRPALER-NLRILTGAKAEKIIIL 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1528361661 227 GT--RAAGV-IVAGERGDETLS-AAREVILAAGAVDTPKLLQLSGVGDpallARHrvplvhalpAVGRNLQDHLC 297
Cdd:pfam00732 157 GRggRAVGVeARDGGGGIKRLItAAKEVVVAAGALNTPPLLLRSGLGK----NPH---------PVGKNLQLHPV 218
 
Name Accession Description Interval E-value
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 1-540 0e+00

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 695.81  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661   1 MTYDYIIVGAGSAGCILANRLSESGRHSVLLLEAGEQDASFWFKVPVGFTKTYYNRRYNWMYYSEPEAQLDGRSLYCPRG 80
Cdd:COG2303     3 EEYDYVIVGAGSAGCVLANRLSEDAGLRVLLLEAGGRDDDPLIRMPAGYAKLLGNPRYDWRYETEPQPGLNGRRLYWPRG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  81 KVVGGSGSINAMVYVRGQRSDYDDWAAAGNAGWAYDDVLPYFRKLETHAAGATDpqHHGTSGPIHITSMKADvHPIVHEF 160
Cdd:COG2303    83 KVLGGSSSINGMIYVRGQPEDFDLWAQLGNQGWGYDDVLPYFKRAEDNERGADA--YHGRSGPLPVSDPPLP-NPLSDAF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 161 LKGCEQLNLPRTDDFNGARFEGAGIYDLNTKHGERCSSSFAYLRPALGRPNLTLRAGVLVRRVTFDGTRAAGVIVAGERG 240
Cdd:COG2303   160 IEAAEELGIPRADDFNGGACEGCGFCQVTCRNGARWSAARAYLPPALKRPNLTVRTGALVTRILFDGGRATGVEYRDDGE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 241 DETLSAAREVILAAGAVDTPKLLQLSGVGDPALLARHRVPLVHALPAVGRNLQDHLCVSFYFKANRPTlndEMGTLLGKV 320
Cdd:COG2303   240 EHTVRAAREVILAAGAINSPQLLLLSGIGPASHLREHGIPVVHDLPGVGRNLQDHLEVSVVFRFKEPV---TLNKSLRKA 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 321 KIGLRYLLTKRGPLAMSVNQAGGFFRGTADTHEPNLQLYFNPLSYRIPKSDRAsikPEPYSGFLIAFNPCRPTSRGTIEI 400
Cdd:COG2303   317 RIGLQYLLTRSGPLTSNVAEAGGFFRSDPGLERPDLQFHFLPLGLTPRWGKKA---LHDGHGFTAHVEQLRPESRGRVTL 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 401 ASNRAEDAAKIRINALTTQKDLDEAVQGSKVIRALMQAPALKAMTVEEISPGPQVDSDEAMRqYFREQSGSIYHLCGSCA 480
Cdd:COG2303   394 DSADPLGAPLIRPNYLSDENDRRVLVAGVRLAREIAAQPALAPYRGEEILPGPDVQSDEELA-FIRARAYTIYHPVGTCR 472

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 481 MGPDaATSVVDASLRVHGLKALRIVDASVFPNITSGNINAPTMMVAEKGADLILADALRG 540
Cdd:COG2303   473 MGTD-PDSVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTIMLAEKAADMILGDYLKN 531
PRK02106 PRK02106
choline dehydrogenase; Validated
 1-534 0e+00

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 585.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661   1 MTYDYIIVGAGSAGCILANRLSESGRHSVLLLEAGEQD--ASFWFKVPVGFTKTYYNRRYNWMYYSEPEAQLDGRSLYCP 78
Cdd:PRK02106    4 MEYDYIIIGAGSAGCVLANRLSEDPDVSVLLLEAGGPDyrWDFFIQMPAALAFPLQGKRYNWAYETEPEPHMNNRRMECP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  79 RGKVVGGSGSINAMVYVRGQRSDYDDWAAAGNAGW-AYDDVLPYFRKLETHAAGATDpqHHGTSGPIHITSMKADVHPIV 157
Cdd:PRK02106   84 RGKVLGGSSSINGMVYIRGNAMDYDNWAELPGLEGwSYADCLPYFKKAETRDGGEDD--YRGGDGPLSVTRGKPGTNPLF 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 158 HEFLKGCEQLNLPRTDDFNGARFEGAGIYDLNTKHGERCSSSFAYLRPALGRPNLTLRAGVLVRRVTFDGTRAAGVIVAG 237
Cdd:PRK02106  162 QAFVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTNGRRWSAARAYLDPALKRPNLTIVTHALTDRILFEGKRAVGVEYER 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 238 ERGDETLSAAREVILAAGAVDTPKLLQLSGVGDPALLARHRVPLVHALPAVGRNLQDHLCVSFYFKANRP-TLNDEMGtL 316
Cdd:PRK02106  242 GGGRETARARREVILSAGAINSPQLLQLSGIGPAEHLKELGIPVVHDLPGVGENLQDHLEVYIQYECKQPvSLYPALK-W 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 317 LGKVKIGLRYLLTKRGPLAMSVNQAGGFFRGTADTHEPNLQLYFNPLSYRipksDRASIKPEPYsGFLIAFNPCRPTSRG 396
Cdd:PRK02106  321 WNKPKIGAEWLFTGTGLGASNHFEAGGFIRSRAGVDWPNIQYHFLPVAIR----YDGSNAVKGH-GFQAHVGPMRSPSRG 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 397 TIEIASNRAEDAAKIRINALTTQKDLDEAVQGSKVIRALMQAPALKAMTVEEISPGPQVDSDEAMRQYFREQSGSIYHLC 476
Cdd:PRK02106  396 SVKLKSADPRAHPSILFNYMSTEQDWREFRDAIRLTREIMAQPALDPYRGREISPGADVQTDEEIDAFVREHAETAYHPS 475

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1528361661 477 GSCAMGPDaATSVVDASLRVHGLKALRIVDASVFPNITSGNINAPTMMVAEKGADLIL 534
Cdd:PRK02106  476 CTCKMGTD-PMAVVDPEGRVHGVEGLRVVDASIMPTITNGNLNAPTIMIAEKAADLIR 532
betA TIGR01810
choline dehydrogenase; Choline dehydrogenase catalyzes the conversion of exogenously supplied ...
 4-534 1.22e-151

choline dehydrogenase; Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli, Staphylococcus xylosus, and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified. [Cellular processes, Adaptations to atypical conditions]


Pssm-ID: 273814 [Multi-domain]  Cd Length: 532  Bit Score: 445.48  E-value: 1.22e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661   4 DYIIVGAGSAGCILANRLSESGRHSVLLLEAGEQDASFWF--KVPVGFTKTYYNRRYNWMYYSEPEAQLDGRSLYCPRGK 81
Cdd:TIGR01810   1 DYIIIGGGSAGSVLAGRLSEDVSNSVLVLEAGGSDYPWDLliQMPAALAYPAGNKRYNWIYETEPEPHMNNRRVGHARGK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  82 VVGGSGSINAMVYVRGQRSDYDDWAAAGNAGW-AYDDVLPYFRKLETHAAGATDpqHHGTSGPIHITSMKADvHPIVHEF 160
Cdd:TIGR01810  81 VLGGSSSINGMIYQRGNPMDYEKWAKPEGMESwDYADCLPYYKRLETTFGGEKP--YRGHDGPIKVRRGPAD-NPLFQAF 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 161 LKGCEQLNLPRTDDFNGARFEGAGIYDLNTKHGERCSSSFAYLRPALGRPNLTLRAGVLVRRVTFDGTRAAGVIVagERG 240
Cdd:TIGR01810 158 IEAGVEAGYNKTPDVNGFRQEGFGPMDSTVHNGRRVSAARAYLHPAMKRPNLEVQTRAFVTKINFEGNRATGVEF--KKG 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 241 D--ETLSAAREVILAAGAVDTPKLLQLSGVGDPALLARHRVPLVHALPAVGRNLQDHLCVSFYFKANRPTLNDEMGTLLG 318
Cdd:TIGR01810 236 GrkEHTEANKEVILSAGAINSPQLLQLSGIGDAEHLRELGIEPRIHLPGVGENLQDHLEVYVQHACKQPVSLYPSLNWLK 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 319 KVKIGLRYLLTKRGPLAMSVNQAGGFFRGTADTHEPNLQLYFNPLSYRIPKSDRASikpepYSGFLIAFNPCRPTSRGTI 398
Cdd:TIGR01810 316 QPFIGAQWLFGRKGAGASNHFEGGGFVRSNDDVDYPNIQYHFLPVAIRYDGTKAPK-----AHGFQVHVGPMYSNSRGHV 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 399 EIASNRAEDAAKIRINALTTQKDLDEAVQGSKVIRALMQAPALKAMTVEEISPGPQVDSDEAMRQYFREQSGSIYHLCGS 478
Cdd:TIGR01810 391 KIKSKDPFEKPEIVFNYMSHEEDWREFREAIRVTREILKQKALDPYRGGEISPGPEVQTDEEIDEFVRRHGETALHPCGT 470

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1528361661 479 CAMGP-DAATSVVDASLRVHGLKALRIVDASVFPNITSGNINAPTMMVAEKGADLIL 534
Cdd:TIGR01810 471 CKMGPaSDEMSVVDPETRVHGMEGLRVVDASIMPRITNGNLNAPVIMMGEKAADIIR 527
Rv0697 TIGR03970
dehydrogenase, Rv0697 family; This model describes a set of dehydrogenases belonging to the ...
 4-534 2.80e-83

dehydrogenase, Rv0697 family; This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function.


Pssm-ID: 274888 [Multi-domain]  Cd Length: 487  Bit Score: 267.84  E-value: 2.80e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661   4 DYIIVGAGSAGCILANRLSESGRHSVLLLEAGE--QDASFW-------FKVPVGFTKTYYnRRYNWMYYSEPeaqldGRS 74
Cdd:TIGR03970   2 DVLIVGAGSAGSVLAARLSEDPSCTVTVLEAGPgyRDPSRLpaqltdgLRLPIGPASPVV-WRYGVELTDGP-----RRA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  75 LYCPRGKVVGGSGSINAMVYVRGQRSDYDdwaAAGNAGWAYDDVLPYFRKLETHAAGATdpQHHGTSGPIHITSmKADVH 154
Cdd:TIGR03970  76 SQIVRGRVLGGSGAVNGGYFCRALPADFD---AWPIPGWSWDDVLPHFRAIETDLDFDG--PLHGTAGPIPVRR-TAELD 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 155 PIVHEFLKGCEQLNLPRTDDFNGARFE---GAGIYDLNTKHGERCSSSFAYLRPALGRPNLTLRAGVLVRRVTFDGTRAA 231
Cdd:TIGR03970 150 GISAAFVAAALGAGFGWIADLNGSGPGlpgGVGAVPLNVDGGRRVSTAVAYLLPALKRPNLTVEADTRVVRILFSGTRAV 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 232 GVIVAGERGDETLSAAReVILAAGAVDTPKLLQLSGVGDPALLARHRVPLVHALPaVGRNLQDHlcvsfyfkanrPtlnd 311
Cdd:TIGR03970 230 GVEVLGDGGPRTLRADR-VVLCAGAVESAHLLLLSGIGPAEQLRAAGIAVVLDLP-VGSDFVDH-----------P---- 292

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 312 emgtllgkvKIGLRYLLTKrgplAMSVNQAGGFFRGTADTHEPNLQLYFNPLSYRIPKSDRasikPEPYSGFLIAfnpcR 391
Cdd:TIGR03970 293 ---------EWVLPYRWRP----THDRPPTSPVLETVLNTADIEIRPYTAGFTALVPGSPR----DDPHLGVALM----R 351

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 392 PTSRGTIEIASNRAEDAAKIRINALTTQKDLDEAVQGSKVIRALMQAPALKAMtveeISPGPQVDSDEAMRQYFreqsGS 471
Cdd:TIGR03970 352 PHSRGRIRLASADPADPPRIEHRYDSSAADRAALRAGAALAHELLGSPELGPL----LEPAVREGEASWVLARL----AT 423

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1528361661 472 IYHLCGSCAMG-PDAATSVVDASLRVHGLKALRIVDASVFPNITSGNINAPTMMVAEKGADLIL 534
Cdd:TIGR03970 424 SQHLCGSCRMGgRDDPGAVVDARCRVRGVEGLWVVDGSILPVIPSRGPHATAVMVAERAAEFLG 487
GMC_oxred_N pfam00732
GMC oxidoreductase; This family of proteins bind FAD as a cofactor.
 71-297 6.85e-48

GMC oxidoreductase; This family of proteins bind FAD as a cofactor.


Pssm-ID: 366272 [Multi-domain]  Cd Length: 218  Bit Score: 165.92  E-value: 6.85e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  71 DGRSLYCPRGKVVGGSGSINAMVYVRGQRSDYDD-WAAAGNAGWAYDDVLPYFRKLEthaagatdpqhhgtsGPIHITSM 149
Cdd:pfam00732  15 NGRRMILPAGSTVGGGSSVNWSACIRTPAAVLDEwASEFGLEGWGYDDYLPYMDKVE---------------GPLGVTTK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 150 KADVHPIVHEFLKGCEQLNLP---RTDDFNGARFEGAGIYDlnTKHGERCSSSFAYLRPALGRpNLTLRAGVLVRRVTFD 226
Cdd:pfam00732  80 GIEESPLNQALLKAAEELGYPveaVPRNSNGCHYCGFCGLG--CPTGAKQSTARTWLRPALER-NLRILTGAKAEKIIIL 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1528361661 227 GT--RAAGV-IVAGERGDETLS-AAREVILAAGAVDTPKLLQLSGVGDpallARHrvplvhalpAVGRNLQDHLC 297
Cdd:pfam00732 157 GRggRAVGVeARDGGGGIKRLItAAKEVVVAAGALNTPPLLLRSGLGK----NPH---------PVGKNLQLHPV 218
GMC_oxred_C pfam05199
GMC oxidoreductase; This domain found associated with pfam00732.
 392-528 6.66e-40

GMC oxidoreductase; This domain found associated with pfam00732.


Pssm-ID: 398739 [Multi-domain]  Cd Length: 143  Bit Score: 141.77  E-value: 6.66e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 392 PTSRGTIEIASNRAEDAAKIRINALTTQKDLDEAVQGSKVIRALMQAPALKAMT-----VEEISPGPQVDSDEAMRQYFR 466
Cdd:pfam05199   1 PRSRGRVTLSSSDPTGLPVIDPNYLSDPADLAALRAALRLARRILAAAGLVLGVeltpgPVPEVSDAAVTSDDELLAYIR 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1528361661 467 EQSGSIYHLCGSCAMGPDAATSVVDASLRVHGLKALRIVDASVFPNITSGNINAPTMMVAEK 528
Cdd:pfam05199  81 AAASTSYHPMGTCRMGADPDDAVVDPDLRVHGVDNLRVVDASVFPSSPSGNPTLTIYALAER 142
PLN02785 PLN02785
Protein HOTHEAD
 2-545 2.93e-28

Protein HOTHEAD


Pssm-ID: 215420 [Multi-domain]  Cd Length: 587  Bit Score: 119.14  E-value: 2.93e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661   2 TYDYIIVGAGSAGCILANRLSEsgRHSVLLLEAGeqdASFWFKVPVGFTKTYYNRRYNWMYYSEPEAQLDGRSLYCPRGK 81
Cdd:PLN02785   55 AYDYIVVGGGTAGCPLAATLSQ--NFSVLLLERG---GVPFGNANVSFLENFHIGLADTSPTSASQAFISTDGVINARAR 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661  82 VVGGSGSINAMVYVRG-----QRSDYDdwaaagnaGWAYDDVLPYFRKLETHAAGATDPQHHGTSGpihitSMKADVHPi 156
Cdd:PLN02785  130 VLGGGTCINAGFYSRAstrfiQKAGWD--------AKLVNESYPWVERQIVHWPKVAPWQAALRDS-----LLEVGVSP- 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 157 vheflkgceqLNLPRTDDFNGARFeGAGIYDlntKHGERCSSsfAYLRPALGRPNLTLRAGVLVRRVTFDGT----RAAG 232
Cdd:PLN02785  196 ----------FNGFTYDHVYGTKV-GGTIFD---EFGRRHTA--AELLAAGNPNKLRVLLHATVQKIVFDTSgkrpRATG 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 233 VIVAGERGDET---LSAAR--EVILAAGAVDTPKLLQLSGVGDPALLARHRVPLVHALPAVGRNLQDHLCVSFYFKANRP 307
Cdd:PLN02785  260 VIFKDENGNQHqafLSNNKgsEIILSAGAIGSPQMLLLSGIGPKKELKKHKIPVVLHNEHVGKGMADNPMNSIFVPSKAP 339

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 308 TLNdemgTLLGKVKIglryllTKRGplaMSVNQAGGFFRGTADTH-------EPNLQLYFNPLSYRIPKSDRASIK---- 376
Cdd:PLN02785  340 VEQ----SLIQTVGI------TKMG---VYIEASSGFGQSPDSIHchhgimsAEIGQLSTIPPKQRTPEAIQAYIHrkkn 406

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 377 --PEPYSGFLIAFNPCRPTSRGTIEIASNRAEDAAKIRINALTTQKDLDEAVQGSKVIRALMQA--------------PA 440
Cdd:PLN02785  407 lpHEAFNGGFILEKIAGPISTGHLSLINTNVDDNPSVTFNYFKHPQDLQRCVYGIRTIEKIVKTnhftnftqcdkqtmEK 486

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1528361661 441 LKAMTVE-EISPGPQVDSD-EAMRQYFREQSGSIYHLCGSCAMGpdaatSVVDASLRVHGLKALRIVDASVFPNITSGNI 518
Cdd:PLN02785  487 VLNMSVKaNINLIPKHTNDtKSLEQFCKDTVITIWHYHGGCHVG-----KVVDQNYKVLGVSRLRVIDGSTFDESPGTNP 561

                         570       580
                  ....*....|....*....|....*..
gi 1528361661 519 NAPTMMVAEKGADLILADALrGEAGGV 545
Cdd:PLN02785  562 QATVMMMGRYMGVKILRERL-GRAAGV 587
Glf COG0562
UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];
1-33 4.69e-06

UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440328 [Multi-domain]  Cd Length: 365  Bit Score: 48.95  E-value: 4.69e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1528361661   1 MTYDYIIVGAGSAGCILANRLSESGRHSVLLLE 33
Cdd:COG0562     1 MMYDYLIVGAGFFGAVFAERLAEELGKKVLVID 33
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-36 1.77e-04

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 44.13  E-value: 1.77e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1528361661   1 MTYDYIIVGAGSAGCILANRLSESGrHSVLLLEAGE 36
Cdd:COG0665     1 ATADVVVIGGGIAGLSTAYHLARRG-LDVTVLERGR 35
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 3-36 3.24e-04

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 42.69  E-value: 3.24e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1528361661   3 YDYIIVGAGSAGCILANRLSESGRHsVLLLEAGE 36
Cdd:TIGR02032   1 YDVVVVGAGPAGASAAYRLADKGLR-VLLLEKKS 33
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 3-33 6.16e-04

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 42.53  E-value: 6.16e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1528361661   3 YDYIIVGAGSAGCILANRLSESGRhSVLLLE 33
Cdd:PTZ00367   34 YDVIIVGGSIAGPVLAKALSKQGR-KVLMLE 63
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
1-37 4.49e-03

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 39.74  E-value: 4.49e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1528361661   1 MTYDYIIVGAGSAGCILANRLSESGRHSVLLLEAGEQ 37
Cdd:COG0579     3 EMYDVVIIGAGIVGLALARELSRYEDLKVLVLEKEDD 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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