|
Name |
Accession |
Description |
Interval |
E-value |
| PBP1_ABC_ligand_binding-like |
cd06336 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
26-367 |
3.97e-137 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380559 [Multi-domain] Cd Length: 345 Bit Score: 395.06 E-value: 3.97e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLEVAGKRYKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06336 1 KIGFLGPLSGPAAAWGLPMLRGLELAADEINAAGGIKVGGKKYKVEVVSYDDKYTPAEAVAAARRLVSQDGVKFIFGPGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIARDLE 185
Cdd:cd06336 81 SAIAAAVQPVTERNKVLLLTAAFSDPILGPDNPLLFRIPPTPYEYAPPFIKWLKKNGPIKTVALIAPNDATGKDWAAAFV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 186 QAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPATAGMIVKQARELGFKGPIVRNGGPATPEIVAVAG 265
Cdd:cd06336 161 AAWKAAGGEVVAEEFYDRGTTDFYPVLTKILALKPDALDLGGSSPGPAGLIIKQARELGFKGPFVSEGGAKADEILKEVG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 266 KAATEGMMVSSLTDPD---NKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTVTDSEKVRNALEAIKNYPG 342
Cdd:cd06336 241 GEAAEGFIGVLPADDDpiaSPGAKAFVERYKKKYGEPPNSESALFYDAAYILVKAMEKAGTVDDTKKIRAALAMLSPDET 320
|
330 340
....*....|....*....|....*
gi 1567725627 343 IQGTLNWGGKAKYGINHQIESPFFI 367
Cdd:cd06336 321 LFGKLKWGGKEIYGINHQLLVPVVV 345
|
|
| LivK |
COG0683 |
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ... |
22-373 |
4.03e-72 |
|
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];
Pssm-ID: 440447 [Multi-domain] Cd Length: 314 Bit Score: 227.89 E-value: 4.03e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 22 QDTLKIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYII 101
Cdd:COG0683 1 ADPIKIGVLLPLTGPYAALGQPIKNGAELAVEEINAAGG--VLGR--KIELVVEDDASDPDTAVAAARKLIDQDKVDAIV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 102 GPMGSAPALAVQPVTEPGKVIIMTLGFTAKALSPEK--PYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQ 179
Cdd:COG0683 77 GPLSSGVALAVAPVAEEAGVPLISPSATAPALTGPEcsPYVFRTAPSDAQQAEALADYLAKKLGAKKVALLYDDYAYGQG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 180 IARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIeLDGNSPATAGMIVKQARELGFKGPIVRnggpatpe 259
Cdd:COG0683 157 LAAAFKAALKAAGGEVVGEEYYPPGTTDFSAQLTKIKAAGPDAV-FLAGYGGDAALFIKQAREAGLKGPLNK-------- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 260 ivavagkaategmmvssltdpdnkavaEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTvTDSEKVRNALEAIKn 339
Cdd:COG0683 228 ---------------------------AFVKAYKAKYGREPSSYAAAGYDAALLLAEAIEKAGS-TDREAVRDALEGLK- 278
|
330 340 350
....*....|....*....|....*....|....
gi 1567725627 340 YPGIQGTLNWGGkakygiNHQIESPFFISEVKDG 373
Cdd:COG0683 279 FDGVTGPITFDP------DGQGVQPVYIVQVKAD 306
|
|
| PBP1_ABC_LivK_ligand_binding-like |
cd06347 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-352 |
4.13e-70 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380570 [Multi-domain] Cd Length: 334 Bit Score: 223.57 E-value: 4.13e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLevagKRYKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06347 1 KIGVIGPLTGEAAAYGQPALNGAELAVDEINAAGGI----LGKKIELIVYDNKSDPTEAANAAQKLIDEDKVVAIIGPVT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALF-PNDESGQQIARDL 184
Cdd:cd06347 77 SSIALAAAPIAQKAKIPMITPSATNPLVTKGGDYIFRACFTDPFQGAALAKFAYEELGAKKAAVLYdVSSDYSKGLAKAF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 185 EQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNsPATAGMIVKQARELGFKGPIVRNGGPATPEIVAVA 264
Cdd:cd06347 157 KEAFEKLGGEIVAEETYTSGDTDFSAQLTKIKAANPDVIFLPGY-YEEAALIIKQARELGITAPILGGDGWDSPELLELG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 265 GKAAtEGMMVSSLTDPDN--KAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTvTDSEKVRNALEAIKNYPG 342
Cdd:cd06347 236 GDAV-EGVYFTTHFSPDDpsPEVQEFVKAYKAKYGEPPNAFAALGYDAVMLLADAIKRAGS-TDPEAIRDALAKTKDFEG 313
|
330
....*....|
gi 1567725627 343 IQGTLNWGGK 352
Cdd:cd06347 314 VTGTITFDPN 323
|
|
| PBP1_ABC_RPA1789-like |
cd06333 |
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, ... |
26-348 |
7.02e-70 |
|
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs; This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380556 [Multi-domain] Cd Length: 342 Bit Score: 223.19 E-value: 7.02e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06333 1 KIGAILSLTGPAASLGIPERNAVELLVEQINAAGG--INGR--KLELIVYDDESDPTKAVTNARKLIEEDKVDAIIGPST 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFRPNLTTEEtsypSIVWLVNHFK---LKKVAALFPNDESGQQIAR 182
Cdd:cd06333 77 TGESLAVAPIAEEAKVPLISLAGAAAIVEPVRKWVFKTPQSDSL----VAEAILDYMKkkgIKKVALLGDSDAYGQSGRA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 183 DLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIeLDGNSPATAGMIVKQARELGFKGPIVRNGGPATPEIVA 262
Cdd:cd06333 153 ALKKLAPEYGIEIVADERFARTDTDMTAQLTKIRAAKPDAV-LVWASGPPAALVAKNLRQLGYKGPIYQSHGAANQDFIK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 263 VAGKAAtEGMMVSSL----------TDPDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTvTDSEKVRN 332
Cdd:cd06333 232 LAGKAA-EGVILPAGkllvadqlpdSDPQKKVLLEFVKAYEAKYGEGPSTFAGHAYDALLLLVEAIEPAGG-TDRAALRD 309
|
330
....*....|....*.
gi 1567725627 333 ALEAIKNYPGIQGTLN 348
Cdd:cd06333 310 ALENTKGLVGVTGVYN 325
|
|
| PBP1_ABC_ligand_binding-like |
cd19980 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-346 |
1.99e-68 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380635 [Multi-domain] Cd Length: 334 Bit Score: 219.02 E-value: 1.99e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLevagKRYKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd19980 1 KIGVIAPLSGPVAALGQQVLNGAKLAVEEINAKGGV----LGRKLELVVEDDKCPPAEGVAAAKKLITDDKVPAIIGAWC 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTlgFTAKA---LSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIAR 182
Cdd:cd19980 77 SSVTLAVMPVAERAKVPLVV--EISSApkiTEGGNPYVFRLNPTNSMLAKAFAKYLADKGKPKKVAFLAENDDYGRGAAE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 183 DLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGnSPATAGMIVKQARELGFKGPIVRNGGPATPEIVA 262
Cdd:cd19980 155 AFKKALKAKGVKVVATEYFDQGQTDFTTQLTKLKAANPDAIFVVA-ETEDGALILKQARELGLKQQLVGTGGTTSPDLIK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 263 VAGKAAtEGMMVSSLTDP--DNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTVTDsEKVRNALEAIKNY 340
Cdd:cd19980 234 LAGDAA-EGVYGASIYAPtaDNPANKAFVAAYKKKYGEPPDKFAALGYDAVMVIAEAIKKAGSTDP-EKIRAAALKKVDY 311
|
....*.
gi 1567725627 341 PGIQGT 346
Cdd:cd19980 312 KGPGGT 317
|
|
| PBP1_ABC_HAAT-like |
cd06349 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-373 |
1.97e-63 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380572 [Multi-domain] Cd Length: 338 Bit Score: 206.27 E-value: 1.97e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKyqsGDAVTATN---RLLSDDGVKYIIG 102
Cdd:cd06349 1 KIGVSGPLTGDNAEYGQQFKNGVELAVDEINAAGG--VNGR--KLELVVYDDQ---GDPKEAVNiaqKFVSDDKVVAVIG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 103 PMGSAPALAVQPVTEPGKVIimTLGFTAKA--LSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQI 180
Cdd:cd06349 74 DFSSSCSMAAAPIYEEAGLV--QISPTASHpdFTKGGDYVFRNSPTQAVEAPFLADYAVKKLGAKKIAIIYLNTDWGVSA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 181 ARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPaTAGMIVKQARELGFKGPIVRNGGPATPEI 260
Cdd:cd06349 152 ADAFKKAAKALGGEIVATEAYLPGTKDFSAQITKIKNANPDAIYLAAYYN-DAALIAKQARQLGWDVQIFGSSSLYSPEF 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 261 VAVAGKAAtEGMMVSSLTDP--DNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGtvTDSEKVRNALEAIK 338
Cdd:cd06349 231 IELAGDAA-EGVYLSSPFFPesPDPEVKEFVKAYKAKYGEDPDDFAARAYDAVNILAEAIEKAG--TDREAIRDALANIK 307
|
330 340 350
....*....|....*....|....*....|....*
gi 1567725627 339 NYPGIQGTLnwggkaKYGINHQIESPFFISEVKDG 373
Cdd:cd06349 308 DFSGLTGTI------TFDENGDVLKSLTILVVKDG 336
|
|
| PBP1_ABC_HAAT-like |
cd06348 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-373 |
2.19e-61 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380571 [Multi-domain] Cd Length: 342 Bit Score: 201.31 E-value: 2.19e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLEVAgkryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06348 1 KIGVALSLTGPGALYGQSQKNGAQLAVEEINAAGGVGGV----KIELIVEDTAGDPEQAINAFQKLINQDKVLAILGPTL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDE----SGQQIa 181
Cdd:cd06348 77 SSEAFAADPIAQQAKVPVVGISNTAPGITDIGPYIFRNSLPEDKVIPPTVKAAKKKYGIKKVAVLYDQDDaftvSGTKV- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 182 rdLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELdGNSPATAGMIVKQARELGFKGPIVRNGGPATPEIV 261
Cdd:cd06348 156 --FPAALKKNGVEVLDTETFQTGDTDFSAQLTKIKALNPDAIVI-SALAQEGALIVKQARELGLKGPIVGGNGFNSPDLI 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 262 AVAGKAAtEGMMVSSLTDPDNK--AVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTVTDSEKVRNALEAIKN 339
Cdd:cd06348 233 KLAGKAA-EGVIVGSAWSPDNPdpKNQAFVAAYKEKYGKEPDQFAAQAYDAAYILAEAIKKAGSTTDRADLRDALARILI 311
|
330 340 350
....*....|....*....|....*....|....
gi 1567725627 340 YPGIQGTLnwgGKAKYGINHQIESPFFISEVKDG 373
Cdd:cd06348 312 AKDFEGPL---GPFSFDADRDGIQPPVVLIVKDG 342
|
|
| Peripla_BP_6 |
pfam13458 |
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ... |
24-373 |
3.70e-61 |
|
Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.
Pssm-ID: 433225 [Multi-domain] Cd Length: 342 Bit Score: 200.58 E-value: 3.70e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 24 TLKIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGP 103
Cdd:pfam13458 1 PIKIGVLTPLSGPYASSGKSSRAGARAAIEEINAAGG--VNGR--KIELVVADDQGDPDVAAAAARRLVDQDGVDAIVGG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 104 MGSAPALAVQPVTEPGKVIImtLGFTAKALSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIARD 183
Cdd:pfam13458 77 VSSAVALAVAEVLAKKGVPV--IGPAALTGEKCSPYVFSLGPTYSAQATALGRYLAKELGGKKVALIGADYAFGRALAAA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 184 LEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIeLDGNSPATAGMIVKQARELGFKGPIVRNGGPA-TPEIVA 262
Cdd:pfam13458 155 AKAAAKAAGGEVVGEVRYPLGTTDFSSQVLQIKASGADAV-LLANAGADTVNLLKQAREAGLDAKGIKLVGLGgDEPDLK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 263 VAGKAATEGMMVSS--LTDPDNKAVAEYAQRYQKKYNKKM-NGFSPAFYDGTHMLFKAMQDAGTVTdSEKVRNALEAIKn 339
Cdd:pfam13458 234 ALGGDAAEGVYATVpfFPDLDNPATRAFVAAFAAKYGEAPpTQFAAGGYIAADLLLAALEAAGSPT-REAVIAALRALP- 311
|
330 340 350
....*....|....*....|....*....|....
gi 1567725627 340 YPGIQGTLNWGGKakygiNHQIESPFFISEVKDG 373
Cdd:pfam13458 312 YDGPFGPVGFRAE-----DHQAVHCMYLVQVKAD 340
|
|
| PBP1_ABC_ligand_binding-like |
cd19984 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-325 |
1.65e-59 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380639 [Multi-domain] Cd Length: 296 Bit Score: 194.74 E-value: 1.65e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd19984 1 KIGVILPLTGDAASYGEDMKNGIELAVEEINAAGG--INGK--KIELIYEDSKCDPKKAVSAANKLINVDKVKAIIGGVC 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFRpnltteetSYPS-------IVWLVNHFKLKKVAALFPNDESGQ 178
Cdd:cd19984 77 SSETLAIAPIAEQNKVVLISPGASSPEITKAGDYIFR--------NYPSdayqgkvLAEFAYNKLYKKVAILYENNDYGV 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 179 QIARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNsPATAGMIVKQARELGFKGPIVRNGGPATP 258
Cdd:cd19984 149 GLKDVFKKEFEELGGKIVASESFEQGETDFRTQLTKIKAANPDAIFLPGY-PKEGGLILKQAKELGIKAPILGSDGFEDP 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1567725627 259 EIVAVAGKAAtEGMMVSSLTDPDN--KAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLfkamqdAGTVT 325
Cdd:cd19984 228 ELLEIAGEAA-EGVIFTYPAFDDSseKKQKFFFYRYKEKYGKEPDIYAALAYDAVMIL------AGDVV 289
|
|
| PBP1_ABC_LIVBP-like |
cd06342 |
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active ... |
26-349 |
2.65e-59 |
|
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.
Pssm-ID: 380565 [Multi-domain] Cd Length: 334 Bit Score: 195.44 E-value: 2.65e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGlevaGKRYKVQLVPYDDKYQSGDAVTATNRLLsDDGVKYIIGPMG 105
Cdd:cd06342 1 KIGVAGPLTGPNAALGQDIRNGAELAVDEINAKGG----GLGFKIELVAQDDACDPAQAVAAAQKLV-ADGVVAVIGHYN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYS-FRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIARDL 184
Cdd:cd06342 76 SGAAIAAAPIYAEAGIPMISPSATNPKLTEQGYKNfFRVVGTDDQQGPAAADYAAKTLKAKRVAVIHDGTAYGKGLADAF 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 185 EQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPAtAGMIVKQARELGFKGPIVRNGGPATPEIVAVA 264
Cdd:cd06342 156 KKALKALGGTVVGREGITPGTTDFSALLTKIKAANPDAVYFGGYYPE-AGLLLRQLREAGLKAPFMGGDGIVSPDFIKAA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 265 GKAAtEGMMVSSLTDPDNK--AVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGtVTDSEKVRNALEAIKnYPG 342
Cdd:cd06342 235 GDAA-EGVYATTPGAPPEKlpAAKAFLKAYKAKFGEPPGAYAAYAYDAAQVLLAAIEKAG-STDRAAVAAALRATD-FDG 311
|
....*..
gi 1567725627 343 IQGTLNW 349
Cdd:cd06342 312 VTGTISF 318
|
|
| PBP1_ABC_ligand_binding-like |
cd06338 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
26-373 |
3.79e-56 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380561 [Multi-domain] Cd Length: 347 Bit Score: 187.79 E-value: 3.79e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLEVAGKRYKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06338 1 KIGASLSLTGPFAGEGKAQKRGYELWVEDVNAAGGVKGGGKKRPVELVYYDDQSDPATAVRLYEKLITEDKVDLLLGPYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKAL-SPEKPYSFRPNLTTEETSYPSIVWLV-NHFKLKKVAALFPNDESGQQIARD 183
Cdd:cd06338 81 SGLTLAAAPVAEKYGIPMIAGGAASDSIfERGYKYVFGVLPPASDYAKGLLDLLAeLGPKPKTVAIVYEDDPFGKEVAEG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 184 LEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNsPATAGMIVKQARELGFKGPIVRNG-GPATPEIVA 262
Cdd:cd06338 161 AREAAKKAGLEVVYDESYPPGTTDFSPLLTKVKAANPDILLVGGY-PPDAITLVRQMKELGYNPKAFFLTvGPAFPAFRE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 263 VAGKAAtEGMMVSSLTDPD-----NKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTvTDSEKVRNALEAI 337
Cdd:cd06338 240 ALGKDA-EGVLGPSQWEPSlpykvFPGAKEFVKAYKEKFGEEPSYHAAAAYAAGQVLQQAIEKAGS-LDPEKVRDALASL 317
|
330 340 350
....*....|....*....|....*....|....*.
gi 1567725627 338 kNYPGIQGTLNWGGKakygiNHQIESPFFISEVKDG 373
Cdd:cd06338 318 -DFDTVYGPIKFDET-----GLQIGKPMVVVQWQGG 347
|
|
| PBP1_ABC_ligand_binding-like |
cd06343 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
23-373 |
1.90e-55 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however its ligand specificity has not been determined experimentally.
Pssm-ID: 380566 [Multi-domain] Cd Length: 355 Bit Score: 186.23 E-value: 1.90e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 23 DTLKIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIG 102
Cdd:cd06343 5 DEIKIGTSLPLSGPAAAYGKPVRAGAAAYFDEVNAAGG--INGR--KIELIVEDDGYDPARAVAAVRKLVEQDKVFAIVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 103 PMGSAPALAVQPVTEPGKVIIMTLGFTAKALSPE-KPYSF--RPNLTTEETSYpsIVWLVNHFKLKKVAALFPNDESGQQ 179
Cdd:cd06343 81 GLGTPTNLAVRPYLNEAGVPQLFPATGASALSPPpKPYTFgvQPSYEDEGRIL--ADYIVETLPAAKVAVLYQNDDFGKD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 180 IARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPATAGmIVKQARELGFKGPIVRNGGPATPE 259
Cdd:cd06343 159 GLEGLKEALKAYGLEVVAEETYEPGDTDFSSQVLKLKAAGADVVVLGTLPKEAAA-ALKEAAKLGWKPTFLGSSVSADPT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 260 IVAVAGKAATEGM----MVSSLTDPDNKAVAEYAQRYQKKYNK-KMNGFSPAFYDGTHMLFKAMQDAGTVTDSEKVRNAL 334
Cdd:cd06343 238 TLAKAGGDAAEGVysasYLKDPTDADDPAVKEFREAYKKYFPDdPPNAYALYGYAAAQVFVEALKRAGKDLTREGLIKAL 317
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1567725627 335 EAIKNYP--GIQGTLNWGGKakygiNHQIESPFFISEVKDG 373
Cdd:cd06343 318 ESLKDFDdgGPGPPVTFSPD-----DHRGIESMYLVQVDGG 353
|
|
| PBP1_ABC_transporter_LIVBP-like |
cd06268 |
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the ... |
26-315 |
3.10e-54 |
|
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily; Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.
Pssm-ID: 380492 [Multi-domain] Cd Length: 298 Bit Score: 181.37 E-value: 3.10e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06268 1 KIGVVVPLTGPYADYGEEILRGVALAVEEINAAGG--INGR--KLELVIADDQGDPETAVAVARKLVDDDKVLAVVGHYS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEK-PYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIARDL 184
Cdd:cd06268 77 SSVTLAAAPIYQEAGIPLISPGSTAPELTEGGgPYVFRTVPSDAMQAAALADYLAKKLKGKKVAILYDDYDYGKSLADAF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 185 EQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIeLDGNSPATAGMIVKQARELGFKGPIVRNGGPATPEIVAVA 264
Cdd:cd06268 157 KKALKALGGEIVAEEDFPLGTTDFSAQLTKIKAAGPDVL-FLAGYGADAANALKQARELGLKLPILGGDGLYSPELLKLG 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1567725627 265 GKAAtEGMMVSS--LTDPDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLF 315
Cdd:cd06268 236 GEAA-EGVVVAVpwHPDSPDPPKQAFVKAYKKKYGGPPSWRAATAYDATQALA 287
|
|
| PBP1_ABC_HAAT-like |
cd19988 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-315 |
2.23e-52 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380643 [Multi-domain] Cd Length: 302 Bit Score: 176.31 E-value: 2.23e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLevagKRYKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd19988 1 KIGVFGPLSGDAAPYGQAMLQGAELAVEEINAAGGI----LGIPIELVVEDDEGLPAASVSAAKKLIYQDKVWAIIGSIN 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPE-KPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGqQIARDL 184
Cdd:cd19988 77 SSCTLAAIRVALKAGVPQINPGSSAPTITESgNPWVFRCTPDDRQQAYALVDYAFEKLKVTKIAVLYVNDDYG-RGGIDA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 185 EQAYA-KAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNsPATAGMIVKQARELGFKGPIVRNGGPATPEIVAV 263
Cdd:cd19988 156 FKDAAkKYGIEVVVEESYNRGDKDFSPQLEKIKDSGAQAIVMWGQ-YTEGALIAKQARELGLKQPLFGSDGLVTPKFIEL 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1567725627 264 AGKAAtEGMM--VSSLTDPDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLF 315
Cdd:cd19988 235 AGDAA-EGAIatTPFLPDSDDPKVSAFVEKYKKRYGEEPDVFAAQAYDAMNILA 287
|
|
| PBP1_ABC_ligand_binding-like |
cd06335 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
26-346 |
2.94e-51 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380558 [Multi-domain] Cd Length: 348 Bit Score: 175.10 E-value: 2.94e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06335 1 KIGVIGPLTGPSAELGESARRGVELAVEEINAAGG--ILGR--KIELVERDDEANPTKAVQNAQELIDKEKVVAIIGPTN 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKAL----SPEKPYSFR--PNLTTEEtsyPSIV-WLVNHfKLKKVAALfpNDES-- 176
Cdd:cd06335 77 SGVALATIPILQEAKIPLIIPVATGTAItkppAKPRNYIFRvaASDTLQA---DFLVdYAVKK-GFKKIAIL--HDTTgy 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 177 GQQIARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPaTAGMIVKQARELGFKGPIVRNGGPA 256
Cdd:cd06335 151 GQGGLKDVEAALKKRGITPVATESFKIGDTDMTPQLLKAKDAGADVILVYGLGP-DLAQILKAMEKLGWKVPLVGSWGLS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 257 TPEIVAVAGKAATEGMMVSSLT-DPDNKAVAEYAQRYQKKYNKKMNGFSPA---FYDGTHMLFKAMQDAGTvTDSEKVRN 332
Cdd:cd06335 230 MPNFIELAGPLAEGTIMTQTFIeDYLTPRAKKFIDAYKKKYGTDRIPSPVSaaqGYDAVYLLAAAIKQAGS-TDGKKIRA 308
|
330
....*....|....
gi 1567725627 333 ALEAIKNYPGIQGT 346
Cdd:cd06335 309 ALENLKGYVGGVKT 322
|
|
| PBP1_ABC_ligand_binding-like |
cd06340 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
26-360 |
7.67e-51 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380563 [Multi-domain] Cd Length: 352 Bit Score: 173.90 E-value: 7.67e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLE-VAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPM 104
Cdd:cd06340 1 KIGVLYPLSGPLALIGQEAKRGAELAVDEINAAGGIKsLGGA--KIELVVADTQSDPEVAASEAERLITQEGVVAIIGAY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 105 GSAPALAVQPVTEPGKVIIMTLGFTAKALSpEK--PYSFRPNLTTE---ETSYPSIVWLV--NHFKLKKVAALFPNDESG 177
Cdd:cd06340 79 SSSVTLAASQVAERYGVPFVTASAVADEIT-ERgfKYVFRTAPTASqfaEDAVDFLKELAkkKGKKIKKVAIIYEDSAFG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 178 QQIARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPATAgMIVKQARELGFKGP--IVRNGGP 255
Cdd:cd06340 158 TSVAKGLKKAAKKAGLEVVLDEPYPAGATDLSSEVLKLKAAKPDVVFATSYTNDAI-LLLRTMKELGFKPKaiIGVGGGY 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 256 ATPEIVAVAGKAAtEGMMVSSLTDPDN----KAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTvTDSEKVR 331
Cdd:cd06340 237 SDPEFLKALGKDA-EGVFSVVPWSPDLakkkPGAKEVNERYKKKYGEDMTGHAARAYTAAWVLADALERAGS-TDPEAIR 314
|
330 340
....*....|....*....|....*....
gi 1567725627 332 nALEAIKNYPGIQGTLNWGGkAKYGINHQ 360
Cdd:cd06340 315 -AAAALTLDIPEGLIMPGGG-VKFDEKGQ 341
|
|
| PBP1_ABC_HAAT-like |
cd19986 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-314 |
1.96e-43 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380641 [Multi-domain] Cd Length: 297 Bit Score: 152.78 E-value: 1.96e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd19986 1 KIGVVAPLTGPAALNGEYQKNGAQLALEEINAAGG--VLGR--PLELVVEDDQGTNTGAVNAVNKLISDDKVVAVIGPHY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSF--RPNlttEETSYPSIV-WLVNHFKLKKVAALFPNDESGQQIAR 182
Cdd:cd19986 77 STQVLAVSPLVKEAKIPVITGGTSPKLTEQGNPYMFriRPS---DSVSAKALAkYAVEELGAKKIAILYDNDDFGTGGAD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 183 DLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIeLDGNSPATAGMIVKQARELGFKGPIVRNGGPATPEIVA 262
Cdd:cd19986 154 VVTAALKALGLEPVAVESYNTGDKDFTAQLLKLKNSGADVI-IAWGHDAEAALIARQIRQLGLDVPVIGSSSFATPTVLL 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1567725627 263 VAGKAAtEGMMVSS--LTDPDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHML 314
Cdd:cd19986 233 LAGEAL-EGIYSVTdfVPSDPDPKVQAFVKKYKAKYGEDPDLYSAWYYDAMYLL 285
|
|
| PBP1_ABC_ligand_binding-like |
cd06345 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-361 |
3.52e-43 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380568 [Multi-domain] Cd Length: 356 Bit Score: 153.96 E-value: 3.52e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSgagAAWGQALLYGAELAADDVNAKGGlevaGKRYKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06345 1 KIGVLGPLS---APAGEAMERGAELAVEEINAAGG----ILGRKVELVVADTQGKPEDGVAAAERLITEDKVDAIVGGFR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALS------PEK-PYSFRPNLTT----EETSYPSIVWLVNHFKLKKVAALFPND 174
Cdd:cd06345 74 SEVVLAAMEVAAEYKVPFIVTGAASPAITkkvkkdYEKyKYVFRVGPNNsylgATVAEFLKDLLVEKLGFKKVAILAEDA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 175 ESGQQIARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIeLDGNSPATAGMIVKQARELGFKGPIVRNGG 254
Cdd:cd06345 154 AWGRGIAEALKKLLPEAGLEVVGVERFPTGTTDFTPILSKIKASGADVI-VTIFSGPGGILLVKQWAELGVPAPLVGINV 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 255 PA-TPEIVAVAGKAAtEGMMVSSL----TDPDNKAVAeYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTvTDSEK 329
Cdd:cd06345 233 PAqDPEFWENTGGAG-EYEITLAFaapkAKVTPKTKP-FVDAYKKKYGEAPNYTAYTAYDAIYILAEAIERAGS-TDPDA 309
|
330 340 350
....*....|....*....|....*....|..
gi 1567725627 330 VRNALEAIkNYPGIQGTLNWGGKAKYgiNHQI 361
Cdd:cd06345 310 LVKALEKT-DYEGVRGRIKFDKKDEY--PHDV 338
|
|
| PBP1_As_SBP-like |
cd06330 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
26-370 |
2.20e-42 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.
Pssm-ID: 380553 [Multi-domain] Cd Length: 342 Bit Score: 151.17 E-value: 2.20e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLevaGKRyKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06330 1 KIGVITPLSGAAAVYGEPARNGAELAVEEINAAGGI---LGR-KIELVVRDDKGKPDEAVRAARELVLQEGVDFLIGTIS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEK--PYSFRPNLTTEETSYPSIVWLV-NHFKLKKVAALFPNDESGQQIAR 182
Cdd:cd06330 77 SGVALAVAPVAEELKVLFIATDAATDRLTEENfnPYVFRTSPNTYMDAVAAALYAAkKPPDVKRWAGIGPDYEYGRDSWA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 183 DLEQAYAKAGSSMSSKE-----FFERqrvDMVPLLTRMMAAGIDAIEldgNSPATAGMI--VKQARELG-FKGPIVRNGG 254
Cdd:cd06330 157 AFKAALKKLKPDVEVVGelwpkLGAT---DYTAYITALLAAKPDGVF---SSLWGGDLVtfVKQAKPYGlFDKTKVVSGL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 255 PATPEIVAVAGKAATEGMMVSSLTD---PDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTvTDSEKVR 331
Cdd:cd06330 231 GGGSEVLQALGKEMPEGLIGGGRYPfgwPDTPLNKAFVEAYRAKYGEYPTYWAYEAYAAVMALKAAIEKAGS-TDTDKVI 309
|
330 340 350
....*....|....*....|....*....|....*....
gi 1567725627 332 NALEAIKnYPGIQGTLNWGGKakygiNHQIESPFFISEV 370
Cdd:cd06330 310 AALEGLT-FDTPGGKITIRAE-----DHQAVQPVVVGTT 342
|
|
| PBP1_ABC_ligand_binding-like |
cd19978 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
25-370 |
9.97e-40 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380633 [Multi-domain] Cd Length: 341 Bit Score: 144.26 E-value: 9.97e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 25 LKIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGkrYKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPM 104
Cdd:cd19978 1 IRLGMSAALSGPAAELGNEMKRGIEAAFNEVNAQGG--VNG--RKIKLIALDDGYEPDRTVKNTKKLIEEDKVFALIGYV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 105 GSAPALAVQPVTEPGKVIIMTLgFT-AKAL-SPEKPYSFrpNL---TTEETSypSIV-WLVNHFKLKKVAALFPNDESGQ 178
Cdd:cd19978 77 GTPTALAALPLANEKKIPLFGP-FTgAEFLrTPFLPYVF--NLrasYADETE--ALVdYLVKTLGPKRIAIFYQNDAFGL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 179 QIARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPATAGMIvKQARELGFKGPIVrNGGPATP 258
Cdd:cd19978 152 AGLEGAKKALKKRGLTPVAEGSYTRNTLDVEEALAKILKAKPEAIILVGTYAPAAEFI-RLARAAGLNPLFA-NVSFVGS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 259 EIVAVAGKAATEGMMVS----SLTDPDNKAVAEYAQRYQKKYNKKMNGFSpAF--YDGTHMLFKAMQDAGTVTDSEKVRN 332
Cdd:cd19978 230 EALALELGDYGEGVIVSqvvpDPNDSSLPIVKEYREAMKKYGPNAPPDFV-SLegYLAARLLVEALKKAGPPLTREKLLA 308
|
330 340 350
....*....|....*....|....*....|....*...
gi 1567725627 333 ALEAIKNYPGIQGTLNWGGKakygiNHQIESPFFISEV 370
Cdd:cd19978 309 LEESLKNDLGKGLTLTFSPN-----DHQGSDKVWLTTL 341
|
|
| PBP1_AmiC-like |
cd06331 |
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system ... |
26-338 |
5.32e-39 |
|
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); This group includes the type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF), found in bacteria and Archaea. AmiC controls expression of the amidase operon by a ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon is induced. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380554 [Multi-domain] Cd Length: 333 Bit Score: 141.97 E-value: 5.32e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06331 1 KIGLLTPLSGPASVYGRAIANGAELAVEEINAAGG--VLGR--PVELVVEDDASDPATAVAAARRLIQQDKVDAIVGPIT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTlgFTAKALSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKkvAALFPNDES-GQQIARDL 184
Cdd:cd06331 77 SATRNAVAPVAERAKVPLLY--PTFYEGGECSPYLFCFGEVPNQQLDPLIPWLMEEYGKK--FYLIGSDYVwPRTMNDAA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 185 EQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIeLDGNSPATAGMIVKQARELGFKGPIVRNGGPATPEIVAVA 264
Cdd:cd06331 153 RRVIEAHGGEVVGEEYLPLGTTDFSSVIEKIKASGADVV-LSTLVGADAVTFLKQFAAAGLRRKVRIAALLFDENTLAGL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 265 GKAATEGM-----MVSSLTDPDNKAvaeYAQRYQKKYNKK---MNGFSPAFYDGTHMLFKAMQDAGTvTDSEKVRNALEA 336
Cdd:cd06331 232 GAEAAEGIysvlsYFQSLDTPENKA---FVAAYRKKFGEDappITSLSEAAYEAVHLYAAAVEKAGS-TDPEAVIAALPG 307
|
..
gi 1567725627 337 IK 338
Cdd:cd06331 308 VS 309
|
|
| PBP1_ABC_ligand_binding-like |
cd06346 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-317 |
9.35e-39 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380569 [Multi-domain] Cd Length: 314 Bit Score: 141.16 E-value: 9.35e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06346 1 KIGALLPLTGPLASLGPPMLAAAELAVEEINAAGG--VLGK--KVELVVEDSQTDPTAAVDAARKLVDVEGVPAIVGAAS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKP--YSFRpnltteetSYPS-------IVWLVNHFKLKKVAALFPNDES 176
Cdd:cd06346 77 SGVTLAVASVAVPNGVVQISPSSTSPALTTLEDkgYVFR--------TAPSdalqgvvLAQLAAERGFKKVAVIYVNNDY 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 177 GQQIARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNsPATAGMIVKQARELGF-KGPIVRNGGP 255
Cdd:cd06346 149 GQGLADAFKKAFEALGGTVTASVPYEPGQTSYRAELAQAAAGGPDALVLIGY-PEDGATILREALELGLdFTPWIGTDGL 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1567725627 256 ATPEIVAVAGKAATEGMMVSSLTDPDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKA 317
Cdd:cd06346 228 KSDDLVEAAGAEALEGMLGTAPGSPGSPAYEAFAAAYKAEYGDDPGPFAANAYDAVMLLALA 289
|
|
| PBP1_SBP-like |
cd06329 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
26-368 |
1.11e-36 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380552 [Multi-domain] Cd Length: 343 Bit Score: 136.25 E-value: 1.11e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLevAGKryKVQLVPYDDKYQSGDAVTATNRLLsDDGVKYIIGPMG 105
Cdd:cd06329 1 KIAFIDPLSGPFASVGEIYLKGLQFAIEEINAGGGL--LGR--KIELVPFDNKGSPQEALIQLKKAI-DQGIRFVLQGNS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTE------PGK-VIIMTLGFTAKALSPEK--PYSFRpnltTEETSYPSIVWLVNHFK----LKKVAALFP 172
Cdd:cd06329 76 SAVAGALIDAIEkhnqrnPDKrVLFLNYGAEAPELTGAKcsFWHFR----FDANADMKMAALADYMKkdgsIKKVYLINQ 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 173 NDESGQQIARDLEQAYAKA--GSSMSSKEFFERQRV-DMVPLLTRMMAAGIDAIeLDGNSPATAGMIVKQARELGFKGPI 249
Cdd:cd06329 152 DYSFGRDVAAAAKKNLKKKrpDIEIVGEDLHPLGKVkDFSPYIAKIKASGADTV-ITGNWGNDLTLLMKAARDSGLKAPF 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 250 VR--NGGPATPEivavAGKAATEGMMVSSLTDPDNKAVAE---YAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTv 324
Cdd:cd06329 231 YTyyADGPGAPA----AIGEAGVGRLVAVAYWHPNPKTPElekFAEAFRAKYGRYPDFNIGRTYMGVEMLAAAIKKAGS- 305
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1567725627 325 TDSEKVRNALEAIKnypgiqgTLNWGGKAKYGI-NHQIESPFFIS 368
Cdd:cd06329 306 TDPEKVAKALEGLS-------FDTPGGPVTMRAdDHQAIQPLYIS 343
|
|
| PBP1_ABC_HAAT-like |
cd19981 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-319 |
1.99e-36 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380636 [Multi-domain] Cd Length: 297 Bit Score: 134.34 E-value: 1.99e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd19981 1 KIGFFAPLTGPAAADGKSALHGAELAVEQINAAGG--INGK--KVELVVYDDQASPKQAVNIAQKLIEQDKVVAVVSGSY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIARDLE 185
Cdd:cd19981 77 SGPTRAAAPIFQEAKVPMVSAYAVHPDITKAGDYVFRVAFLGPVQGRAGAEYAVKDLGAKKVAILTIDNDFGKSLAAGFK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 186 QAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSpATAGMIVKQARELGFKGPIVRNGGPATPEIVAVAG 265
Cdd:cd19981 157 EEAKKLGAEIVSEYAYALGDRDFRPILTKIKSANPDAIYASGYY-AEAAPIVKQARELGIKVPIIGQEGYDSPKFIEIAG 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1567725627 266 KAAtEGMMV--SSLTDPDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQ 319
Cdd:cd19981 236 SAA-EGVIIttSLNRDSDRPITQKFIKEYRKRYGIDPDMVAASTYDAVMVLAGEVQ 290
|
|
| PBP1_ABC_HAAT-like |
cd19983 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-315 |
2.73e-36 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380638 [Multi-domain] Cd Length: 303 Bit Score: 134.25 E-value: 2.73e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKyQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd19983 1 RIGFVGGLTGRYSDLGVQGRNGAQLAVEEINAAGG--INGR--PVELIIRDDQ-QDPEAAKAADRELIAGGVVAIIGHMT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALF--PNDESGQQIARD 183
Cdd:cd19983 76 SAMTVAVLPVINEAKVLMISPTVSTPELSGKDDYFFRVTPTTRESAQALARYAYNRGGLRRVAVIYdlSNRAYSESWLDN 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 184 LEQAYAKAGSSMSSKEFFE-RQRVDMVPLLTRMMAAGIDAIELDGNSPATAgMIVKQARELGFKGPIVRNGGPATPEIVA 262
Cdd:cd19983 156 FRSEFEALGGRIVAEIPFSsGADVDFSDLARRLLASKPDGLLLVASAVDTA-MLAQQIRKLGSKIPLFSSAWAATEELLE 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1567725627 263 VAGKAAtEGMMVSSLTDPDNKAVA--EYAQRYQKKYNKKMNgFSPAF-YDGTHMLF 315
Cdd:cd19983 235 LGGKAV-EGMLFSQAYDRNSSNPRylAFKEAYEERFGREPS-FAAAYaYEAAMVLA 288
|
|
| PBP1_ABC_HAAT-like |
cd06344 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-348 |
9.15e-34 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380567 [Multi-domain] Cd Length: 332 Bit Score: 128.11 E-value: 9.15e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 27 IGAVVTLSGAGaawgQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMGS 106
Cdd:cd06344 4 IGVAWPFAPDG----DLFLEGVELAVEEINAAGG--VLGR--KIRLVEYDDEASVDKGLAIAQRFADNPDVVAVIGHRSS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 107 APALAVQPVTEPGKVIIMTLGFTAKALSPEK-PYSFRpNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIARDLE 185
Cdd:cd06344 76 YVAIPASIIYERAGLLMLSPGATAPKLTQHGfKYIFR-NIPSDEDIARQLARYAARQGYKRIVIYYDDDSYGKGLANAFE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 186 QAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAG-IDAIELDGNSPAtAGMIVKQARELGFKGPIVRNGGPATPEIVAVA 264
Cdd:cd06344 155 EEARELGITIVDRRSYSSDEEDFRRLLSKWKALDfFDAIFLAGSMPE-GAEFIKQARELGIKVPIIGGDGLDSPELIEIA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 265 GKAAtEGMMVSSLTDPD--NKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTvTDSEKVRNALEAIKNYPG 342
Cdd:cd06344 234 GKAA-EGVVVATVFDPDdpRPEVRAFVEAFRKKYGREPDVWAAQGYDAVKLLAEAIEKAGS-TVPAKIASALRFLENWEG 311
|
....*.
gi 1567725627 343 IQGTLN 348
Cdd:cd06344 312 VTGTYS 317
|
|
| PBP1_RPA0668_benzoate-like |
cd20014 |
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the ... |
26-338 |
7.39e-32 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380667 [Multi-domain] Cd Length: 346 Bit Score: 123.11 E-value: 7.39e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKgglevAGKRyKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd20014 1 KIGLLLPYSGVYAALGEDIRNGFQLYLDEHGGK-----LGGR-PIELVKEDDEADPDVALQKARKLIEQDKVDVLVGPVS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEK--PYSFRPNLTTEETSYPSIVWLVNHFKlKKVAALFPNDESGQQIARD 183
Cdd:cd20014 75 SGVALAIRDVVEQAKVPLIVANAGANALTRAAcsPYIFRTSFSNWQLGYALGKYAAENVG-KTVVTIASDYAAGREVVAG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 184 LEQAYAKAGSSMsSKEFFER--QRVDMVPLLTRMMAAGIDAIeLDGNSPATAGMIVKQARELGFKG--PIVRNGGPATPE 259
Cdd:cd20014 154 FKEGFEAAGGKV-VGEIWTPlgTTTDFSPYLTQIAASGPDAV-YAFFAGADAVRFVKQYAEFGLKGkiPLYGPGFLTDED 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 260 IVAVAGKAAtEGMM-----VSSLTDPDNKAvaeYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDA-GTVTDSEKVRNA 333
Cdd:cd20014 232 VLPALGEAA-EGIItvlhyAPTLDNPANRA---FVAAYQAKYGRLPDVYAVQGYDAAQVIDAALEAVgGDTSDKDILAAA 307
|
....*
gi 1567725627 334 LEAIK 338
Cdd:cd20014 308 LELGS 312
|
|
| PBP1_ABC_ligand_binding-like |
cd06326 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
25-340 |
9.01e-32 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380549 [Multi-domain] Cd Length: 339 Bit Score: 122.65 E-value: 9.01e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 25 LKIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPM 104
Cdd:cd06326 1 IVIGQSAPLSGPLAELGREYLAGAKAYFDQVNAAGG--INGR--KIRLVTLDDGYDPARTVENTRQLIEQDKVVALFGYV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 105 GSAPALAVQPVTEPGKV-IIMTLGFTAKALSPEKPYSF--RPNLTTEetsypsIVWLVNHFK---LKKVAALFPNDESGQ 178
Cdd:cd06326 77 GTANVEAVLPLLEEAGVpLVGPLTGADSLREPGNPYVFhvRASYADE------VEKIVRHLAtlgLKRIAVVYQDDPFGK 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 179 QIARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPATAGMIvKQARELGFKGPIVrNGGPATP 258
Cdd:cd06326 151 EGLAAAEAALAARGLEPVATAAVARNAADVAAAAAALAAAKPQAVVLIAAGKAAAAFI-KALRAAGGAAQFY-GLSVVGA 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 259 EIVAVAGKAATEGMMVSSLT-DPDNKA---VAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTVTDSEKVRNAL 334
Cdd:cd06326 229 AALAKALGDAARGVVVSQVVpNPWSTTlplVREYQAAMKAAGPKEPSYASLEGYIAARVLVEALRRAGRNPTRESLVAAL 308
|
....*.
gi 1567725627 335 EAIKNY 340
Cdd:cd06326 309 ESLGRL 314
|
|
| PRK15404 |
PRK15404 |
high-affinity branched-chain amino acid ABC transporter substrate-binding protein; |
1-352 |
1.87e-30 |
|
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
Pssm-ID: 237959 [Multi-domain] Cd Length: 369 Bit Score: 119.74 E-value: 1.87e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 1 MKSICTALIPAVLLLAAPAHAQ-DTLKIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKY 79
Cdd:PRK15404 1 MKSKGKTLLAGCIALALSHAALaDDIKIAIVGPMSGPVAQYGDMEFTGARQAIEDINAKGG--IKGD--KLEGVEYDDAC 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 80 QSGDAVTATNRLLSdDGVKYIIGPMGSAPALAVQPVTEPGKVIIMTLGFTAKALSPEKP-YSFRpnlTTEETSYPSIV-- 156
Cdd:PRK15404 77 DPKQAVAVANKVVN-DGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYqLIFR---TIGLDSDQGPTaa 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 157 -WLVNHFKLKKVAALFPNDESGQQIARDLEQAYAKAGSSMSskeFFERQRV---DMVPLLTRMMAAGIDAIELDGNSPAT 232
Cdd:PRK15404 153 kYILEKVKPKRIAVLHDKQQYGEGLARSVKDGLKKAGANVV---FFEGITAgdkDFSALIAKLKKENVDFVYYGGYHPEM 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 233 aGMIVKQARELGFKGPIVRNGGPATPEIVAVAGKAAtEGMMV----SSLTDPDNKAVAEYAQryQKKYNKkmngfSPAF- 307
Cdd:PRK15404 230 -GQILRQAREAGLKTQFMGPEGVGNKSLSNIAGPAS-EGMLVtlpkRYDQDPANKAIVDAFK--AKKQDP-----SGPFv 300
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1567725627 308 ---YDGTHMLFKAMQDAGTvTDSEKVRNALEAiKNYPGIQGTLNWGGK 352
Cdd:PRK15404 301 wttYAAVQSLAAGINRAGS-DDPAKVAKYLKA-NTFDTVIGPLSWDEK 346
|
|
| PBP1_SBP-like |
cd19989 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
26-320 |
4.19e-30 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380644 [Multi-domain] Cd Length: 299 Bit Score: 117.38 E-value: 4.19e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd19989 1 KIGVLTPLSGPYAALGEEARRGAQLAVEEINAAGG--ILGR--PVELVVEDTEGKPATAVQKARKLVEQDGVDFLTGAVS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEK--PYSFRPNLTTEETSYPSIVWLVNhFKLKKVAALFPNDESGQQIARD 183
Cdd:cd19989 77 SAVALAVAPKAAELKVPYLVTVAADDELTGENcnRYTFRVNTSDRMIARALAPWLAE-NGGKKWYIVYADYAWGQSSAEA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 184 LEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELdgnspATAG----MIVKQARELGFKG--PIVRNGGPAT 257
Cdd:cd19989 156 FKEAIEELGGEVVGTLFAPLGTTDFSSYITQISDSGADGLLL-----ALAGsdavNFLKQAGQFGLGKkyKIVGGILSIE 230
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1567725627 258 PEIVAVAGKAAtEGMM-----VSSLTDPDNKAVAEYaqrYQKKYNKKMNGFSPAFYDGTHMLF-KAMQD 320
Cdd:cd19989 231 PLALPALGDAA-EGVYggvryPPTLDTPANRAFVEA---YEKEYGEAPDNFAGEAYEAMQALAhQAVQP 295
|
|
| PBP1_ABC_ligand_binding-like |
cd19979 |
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes ... |
26-343 |
6.70e-28 |
|
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380634 [Multi-domain] Cd Length: 350 Bit Score: 112.32 E-value: 6.70e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLevAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd19979 1 VIGLDADLSGGSAASGEAIKRGIQLAIDEINAAGGL--LGR--KLELVAKDHRGNPARGVDNLREFAADPDVLAVFGGLH 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVtePGKVIIMTLGFTAKALS----PEKP-YSFRPNLTTEEtsypSIVWLVNHF---KLKKVAALFPNDESG 177
Cdd:cd19979 77 SPVLLAELDF--IHELKIPYLVPWAAATPitrnGYSPnYIFRLSVDDSL----AGPFLVEYAlkkGCKRPALLLENTGWG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 178 QQIARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPATAgMIVKQARELGFKGPIVRNGGPA- 256
Cdd:cd19979 151 RSNLKAMTKALAKKGLQPVGVEWFNWGDTDAKPQLRALKAAGADAILLVANAPEGA-AIVKALAALPERLPIISHWGITg 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 257 --TPEIVAVAGKAA------TegmmVSSLTDPDNKAVAEYAQRYQKKYNKK--------MNGFSPAfYDGTHMLFKAMQD 320
Cdd:cd19979 230 gdFPELPREALSKIdlrfiqT----FSFFDANQSPRGKQVLARYKRRYPVEdpesdipaPVGFAHA-YDLTHLLALAIEQ 304
|
330 340
....*....|....*....|...
gi 1567725627 321 AGTvTDSEKVRNALEAIKNYPGI 343
Cdd:cd19979 305 AGS-TDRAAVRAALELLPPHEGL 326
|
|
| PBP1_aromatic_compounds-like |
cd06332 |
type 1 periplasmic binding proteins of active transport systems predicted to be involved in ... |
26-370 |
1.31e-27 |
|
type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.
Pssm-ID: 380555 [Multi-domain] Cd Length: 336 Bit Score: 111.15 E-value: 1.31e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAkgglEVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06332 1 KIGLLAPLTGPFAALGEDMVRGFELALEEVGG----EVAGR--KVELVVEDDAGDPDTAVTKARKLVEQDKVDVLIGPLS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPV-TEPGKVIIMTLGFTAK-ALSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIARD 183
Cdd:cd06332 75 GDEGLAVAPYaKEPGVPFINPVAGADDlTQRAKAPNFFRTSFTGSQWSAPLGDYAYKELGYKKVATIGSDYAFGYEQAAG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 184 LEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGiDAIeLDGNSPATAGMIVKQARELGFKG--PIVRNGGPATPEIV 261
Cdd:cd06332 155 FKRGFEAAGGEVVQEIWVPLGTTDFSPYIAQIPSAD-DAV-FAFLGGADAVRFLKQYREFGLKDkiPLIGGGTTVDESVL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 262 AVAGKAAtEGMMVSSLT--DPDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDA-GTVTDSEKVRNALEAIK 338
Cdd:cd06332 233 PAMGDAA-LGIISASHYaeGLDNPENKKFVAAYKKKFGKLPSLYAAGGYDGAQAILEALEAVgGDVSDKQALAAALRKVK 311
|
330 340 350
....*....|....*....|....*....|..
gi 1567725627 339 nYPGIQGTLNWGGkakygiNHQIESPFFISEV 370
Cdd:cd06332 312 -FDSPRGPFSFDE------NRNPVQNVYIREV 336
|
|
| PBP1_ABC_ligand_binding-like |
cd06341 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
26-340 |
7.47e-26 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380564 [Multi-domain] Cd Length: 340 Bit Score: 106.62 E-value: 7.47e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06341 1 KIGLIYPDTGPGAASFSAARAGAEARFGLANAAGG--INGR--KVEYVWCDDQSDPATNLQAARQLVEDEKVFALVGSSS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGkviIMTLGFTAkALSPEKPYSFRPNLTTEETSYPSIV-WLVNHFKLKKVAALF-PNDESGQQIARD 183
Cdd:cd06341 77 AASGSANDYLAQAG---IPVVGGAG-VSVWCFRNMFSNFFSLGGGGSTTTYgQYAAALGGTKAAVVVtDIPAASQQLAQQ 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 184 LEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPATAGmIVKQARELGFKGPIVRNGGPATPEIVAV 263
Cdd:cd06341 153 LAASLRAAGVEVVGTAPYAAAAPDYTAVAQAAKAAGADAVVGVLDPDVAAR-VLKAARAQGLDLKVALSPSGYDPSVLAA 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 264 AGkAATEGMMVSS------LTDPDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTVTDSEKVRNALEAI 337
Cdd:cd06341 232 YG-AALAGVSVAStflpfeADTPAVKAYRAAMAKYAPELQDPLQQFALSGYIAADLFVRGLEAAGGCPTRAAFIKALRDV 310
|
...
gi 1567725627 338 KNY 340
Cdd:cd06341 311 KDY 313
|
|
| PBP1_alkylbenzenes-like |
cd06360 |
type 1 periplasmic binding component of active transport systems predicted be involved in ... |
26-338 |
2.65e-24 |
|
type 1 periplasmic binding component of active transport systems predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; This group includes the type 1 periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.
Pssm-ID: 380583 [Multi-domain] Cd Length: 357 Bit Score: 102.37 E-value: 2.65e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVnakgGLEVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06360 1 KIGVLLPLTGPLAVNGEDVRDGFELYFDEI----GNQVAGR--KIELIVEDDEGKPDVGLTKARKLVERDKVHVLAGIVS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEK--PYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIARD 183
Cdd:cd06360 75 SAVAYAVRDYVVEQKIPLVISNAGAAPLTQELasPYIFRTSFSNGQYDAPFGQYAYEKLGYRRIAVMASDYAAGHEQAGA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 184 LEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIeLDGNSPATAGMIVKQARELGFKG--PIVRNGGPATPEIV 261
Cdd:cd06360 155 FARTFKQAGGKVVQEIYPPLGTADFAPYLARIQQDAADAV-WAFFAGADAIRFVKQYDEYGLKGklPLVGIGGLVDDAIL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 262 AVAGKAATeGMMVSS-----LTDPDNKAvaeYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDA-GTVTDSEKVRNALE 335
Cdd:cd06360 234 PEQGDAAL-GIVSYLhysaaLDTPENKA---FVQAYRKKYGRDPGLYAEGGYVAARAIAEALEAVkGNVEDKEAFLEALR 309
|
...
gi 1567725627 336 AIK 338
Cdd:cd06360 310 KVR 312
|
|
| PBP1_ABC_ligand_binding-like |
cd19982 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
26-309 |
3.85e-24 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380637 [Multi-domain] Cd Length: 302 Bit Score: 101.20 E-value: 3.85e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd19982 1 KIGAILSLTGPFAPFGEMFKNGYEMALEEINAAGG--IKGK--KLELVIEDDQSKPQTALAAAEKLVSQDKVPLIVGGYS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTA-KALSPEKPYSFRPNLTTeeTSYPSIVW--LVNHFKLKKVAALFPNDESGQQIAR 182
Cdd:cd19982 77 SGITLPVAAVAERQKIPLLVPTAADdDITKPGYKYVFRLNPPA--SIYAKALFdfFKELVKPKTIAILYENTAFGTSVAK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 183 DLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSpATAGMIVKQARELGFKGPIV--RNGGPATPEI 260
Cdd:cd19982 155 AARRFAKKRGIEVVADESYDKGATDFKPLLNKVKAANPDVVYMVSYL-NDAILLMRQAKELGLNPKLFagGGAGFTIPEF 233
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1567725627 261 VAVAGKAAtEGMMVSSLTDPDNK--AVAEYAQRYQKKYnkkmnGFSPAFYD 309
Cdd:cd19982 234 LKQAGPLA-EYVVTATLWSPDVKypGAKEFYEKYKAKY-----GVEPSYHE 278
|
|
| ANF_receptor |
pfam01094 |
Receptor family ligand binding region; This family includes extracellular ligand binding ... |
48-362 |
1.57e-22 |
|
Receptor family ligand binding region; This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.
Pssm-ID: 460062 [Multi-domain] Cd Length: 347 Bit Score: 97.46 E-value: 1.57e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 48 AELAADDVNAKGGLEvagKRYKVQLVPYDDKYQSGDAVTATNRLLSDDgVKYIIGPMGSAPALAVQPVTEPGKVIIMTLG 127
Cdd:pfam01094 6 VRLAVEDINADPGLL---PGTKLEYIILDTCCDPSLALAAALDLLKGE-VVAIIGPSCSSVASAVASLANEWKVPLISYG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 128 FTAKALSPEKPYSFRPNLTTEETSY-PSIVWLVNHFKLKKVAALFPNDESGQQIARDLEQAYAKAGSSMSSKEFFERQRV 206
Cdd:pfam01094 82 STSPALSDLNRYPTFLRTTPSDTSQaDAIVDILKHFGWKRVALIYSDDDYGESGLQALEDALRERGIRVAYKAVIPPAQD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 207 D---MVPLLTRmMAAGIDAIELDGNSPaTAGMIVKQARELGFKGP----IVRNGGPATPEIVAVAGKAATEGMMVSSLTD 279
Cdd:pfam01094 162 DdeiARKLLKE-VKSRARVIVVCCSSE-TARRLLKAARELGMMGEgyvwIATDGLTTSLVILNPSTLEAAGGVLGFRLHP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 280 PDNKAVAEYAQRY---QKKYNKKMNGFSPA----FYDGTHMLFKAMQDAGTvtdSEKVRNALEAIKNYPGIQGTLNWGGK 352
Cdd:pfam01094 240 PDSPEFSEFFWEKlsdEKELYENLGGLPVSygalAYDAVYLLAHALHNLLR---DDKPGRACGALGPWNGGQKLLRYLKN 316
|
330
....*....|.
gi 1567725627 353 AKY-GINHQIE 362
Cdd:pfam01094 317 VNFtGLTGNVQ 327
|
|
| PBP1_ABC_ligand_binding-like |
cd06334 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
26-340 |
1.05e-19 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380557 [Multi-domain] Cd Length: 360 Bit Score: 89.22 E-value: 1.05e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGpMG 105
Cdd:cd06334 1 KIGLLTDLTGPTADVGKPYAQGVRDYLNYVNEEGG--INGV--KIELEECDTGYKVPRAVACYKRLKAQDGVVAILG-WG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALS-PEK-PYSFRPNltteeTSYPS-----IVWLVNHFKL----KKVAALFPND 174
Cdd:cd06334 76 TGDTEALAPRVAKDKIPYISASYGRSLADdGKVfPYNFFVG-----ATYSSqaralLKYIAQEWGGklkgPKVAFVYHDS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 175 ESGQQIARDLEqAYAKA-GSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPATAgMIVKQARELGFKGPIVRNG 253
Cdd:cd06334 151 PFGREPIPALK-AYAKElGFEVVAEQVPSPGALDATAQWLRIRRAGPDYVIIQGTGGSVA-VIIKDAKRLGLKTKFIGNI 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 254 GPATPEIVAVAGKAAtEGMMVSSLTDPDNKAVAeyAQRYQKKYNKKMNGFSPAFYDGTH---------MLFKAMQDA--- 321
Cdd:cd06334 229 WGGDEDLIKLAGDAA-EGYVGVSPFAFGTDDPP--GKEIVEEVAKKGKGDGPEEVGTVYynrgwatamLAVEAIRRAdka 305
|
330 340
....*....|....*....|
gi 1567725627 322 -GTVTDSEKVRNALEAIKNY 340
Cdd:cd06334 306 gGGTGLGNKLKAGLERLKDF 325
|
|
| PBP1_SBP-like |
cd06328 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
26-335 |
3.38e-19 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative and gram-positive bacteria. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380551 [Multi-domain] Cd Length: 336 Bit Score: 87.74 E-value: 3.38e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADdVNAKGGLEVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06328 1 KIGVITSLTGPLAAYGKQTERGFELGLE-YATDGTMEVDGR--KIEVIVKDDQGDPDTAKAAATELIGDDGVDILVGTVS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEK--PYSFRPNLTTEE--TSYPSIVWLVNHfklKKVAALFPNDESGQQIA 181
Cdd:cd06328 78 SAVALALAPVAEQNKKILIVGPAAADSITGENwnKYTFRTSRNSWQdaIAGAKALADPLG---KSVAFLAQDYAFGQDGV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 182 RDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPATAGMIvKQARELGFKGPI-VRNGGPATPeI 260
Cdd:cd06328 155 AAFKKALEAKGGKIVGEELVPVTTTDFTPYLQRILDAKPDVLFVAWAGTGALTLW-QQLADQGVLDDIkVVTGGPDIA-T 232
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1567725627 261 VAVAGKAAT--EGMMVSSLTDPDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTVTDSEKVRNALE 335
Cdd:cd06328 233 LAALGDALPgiEGLTYYYYGLPKNPVNDWLVKAHKERYNAPPDLFTAGGFAAAQAVVRALEKAGGDTDVEKLIAALE 309
|
|
| PBP1_RPA0985_benzoate-like |
cd20013 |
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the ... |
26-340 |
1.07e-18 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0985 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0985 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380666 [Multi-domain] Cd Length: 356 Bit Score: 86.54 E-value: 1.07e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAAddvnAKGGLEVAGKryKVQLVPYDDKYQSGD-AVTATNRLLSDDGVKYIIGPM 104
Cdd:cd20013 1 KVGVIGPFSGPFADYGKQFDRGIDLYL----KLHGDKVGGR--KVEVIYRDDGGPNPAvAKRLAQELIVRDKVQILIGFG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 105 GSAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFRPNLTTEETSYPSIVWLVNHfKLKKVAALFPNDESGQQIARDL 184
Cdd:cd20013 75 FTPNALAVAPVATEAKTPTVIMNAATSSITRKSPYFVRTSFTMWQVAYPMGKWAAKN-GIKKAYTAVADYAPGHDAETAF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 185 EQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDGNSPATAGMIVKQARELGFK--GPIVRNGGPATPEIVA 262
Cdd:cd20013 154 KKAFEAAGGKIVGSIRVPLATPDFAPFMQRIKDAKPDAVFVFVPAGAPSIGFLKAYAERGLKeaGIKLLGTGDATDDDDL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 263 VAGKAATEGMMVS-----SLTDPDNKAvaeYAQRYQKKYNKKM--NGFSPAFYDGTHMLFKAMQDAGTVTDSEKvrnALE 335
Cdd:cd20013 234 PAMGDAALGLITAghysaALDSPENKA---FVAAYQKAYGPDArpDFMAVAAYDGMALIYKMIKATGGKFDGDK---AMA 307
|
....*
gi 1567725627 336 AIKNY 340
Cdd:cd20013 308 AVKGL 312
|
|
| PBP1_YraM_LppC_lipoprotein-like |
cd06339 |
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup ... |
26-347 |
4.44e-18 |
|
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).
Pssm-ID: 380562 [Multi-domain] Cd Length: 331 Bit Score: 84.24 E-value: 4.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAkgglevagkrYKVQLVPYDDKyQSGDAVTATNRLLsDDGVKYIIGPMG 105
Cdd:cd06339 1 RIALLLPLSGPYAAAGQAIRDGIELALFDAGG----------SRPELRVYDTG-GPEGAAAAYQQAV-AEGADLIIGPLL 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFrpNLTTEETsypsIVWLVNHFK---LKKVAALFPNDESGQQIAR 182
Cdd:cd06339 69 KSSVAALAAAAQALGVPVLALNNDESATAGPGLFQF--GLSPEDE----ARQAARYAVqqgLRRFAVLAPDNAYGQRVAN 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 183 DLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAA----------------------GIDAIELDGNsPATAGMIVKQA 240
Cdd:cd06339 143 AFREAWQALGGTVVAVESYDPDETDFSAAIRRLLGVdqsearirqlgellefeprrrqDFDAIFLPAG-PEQARLIAPQL 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 241 RELGFKG-PIVRNGGPATPEIVAVAGKAAtEGMMvssLTDPDNKAVA-EYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAM 318
Cdd:cd06339 222 AFYGAGDvPLLGTSLWYSGKLNLLRDPDL-NGAW---FADPPWLLSPrAFPLRYRLAYGWPPPRLAALGYDAYRLAARLA 297
|
330 340
....*....|....*....|....*....
gi 1567725627 319 QDagtvtdsekvRNALEAIKNYPGIQGTL 347
Cdd:cd06339 298 RL----------GGGLTPGAGFSGLTGLL 316
|
|
| PBP1_SBP-like |
cd19987 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
26-371 |
2.68e-17 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380642 [Multi-domain] Cd Length: 353 Bit Score: 82.38 E-value: 2.68e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLEVAGKR--------YKVQLVPYDDKYQSGDAVTATNRLLSDDGV 97
Cdd:cd19987 1 TIGLNVPLSGPYAPQGEDQRRGFELAVDHLNNGGGLVDKDSRlsgdgilgKKVELVTADTETKADTAVDNAKRLIEQDGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 98 KYIIGPMGSAPALAVQPVTEPGKVIIMtLGFT-AKALSPEK--PYSFRPnLTTEETSYPSIV-WLVNHF-KLKKVAALFP 172
Cdd:cd19987 81 VMITGGSSSAVAVAAQKLAQKEGVLYF-AGLShSNDTTGKDchRYGFRE-CFNAHMSAKALApYLVEKFgKDRKYFYLTA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 173 NDESGQQIARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELD--GNSPATAgmiVKQARELGFKGPIV 250
Cdd:cd19987 159 DYTWGHSTEQSMREYTEAHGWKTVGNPATPLGETDFSAALLNAADSGADVLVLVlfGRDMVNA---LKQAKQFGLLKKMD 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 251 RNGGPATPEIVAVAGKAATEGMMVS-----SLTDPDNKAVAEyAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTVt 325
Cdd:cd19987 236 IVVPLLTAFMAESVGPEIMEGVLGTvnwhwSLPDDYSYAFGK-AEAFEKEYGAYPSQAAASAYVQVLQYAAAVERAGSF- 313
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1567725627 326 DSEKVRNALEaiknypGIQGTLNWGGKAKYGINHQIESPFFISEVK 371
Cdd:cd19987 314 DPPAVIRALE------GHEYTLLKGEQYWRACDHQSVRPVYVVRGK 353
|
|
| PBP1_SBP-like |
cd20378 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
26-371 |
5.06e-17 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380668 [Multi-domain] Cd Length: 357 Bit Score: 81.62 E-value: 5.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLevagkryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd20378 1 TLGGLVSMSGAFAAAGKLADRGMRLAVEEYGGALGR-------PLKYITRDTEGKPGTGVRKVQEAIAQDGARFFIGGTL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLG----FTAKALSpekPYSFR---PNLTTEETSYPSIVWLvnHFKLKKVAALFPNDESGQ 178
Cdd:cd20378 74 SSVALAVSEEAEKAGGVYITSGgadeITGSRCN---RSTFRwsvPTYGAIRQTVRPVIKA--MPKAKRWYTITPQYVFGE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 179 QIARDLEQAYAKAG--------SSMSSKEFFErqrvdmvpLLTRMMAAGIDAIELDgNSPATAGMIVKQARELGFKgPIV 250
Cdd:cd20378 149 SLLKNAKEVLKEKGiehvgnsyHSLGEREFSG--------YLTKAMAARPDVLLIL-NFGSQAVDALRQAVSFGLK-RKM 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 251 RNGGPATPEI--VAVAGKAATEGMMVSS-----LTDPDNKAVAEyaqRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGT 323
Cdd:cd20378 219 KILVAWSSGLdqFQELGPDICEGVYFGAqywhdVDTPANKALVK---VYQAKFKETPSYALAAGYACTRMLLDAIDKAGS 295
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1567725627 324 vTDSEKVRNALEAIKnYPGIQGTLNWGGKakygiNHQIESPFFISEVK 371
Cdd:cd20378 296 -TDPAAVIKALEGLK-YDGITGDEEVRAA-----DHQVLKPYYLLRGK 336
|
|
| PBP1_ABC_ligand_binding-like |
cd06337 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
26-357 |
3.67e-16 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380560 [Multi-domain] Cd Length: 354 Bit Score: 78.88 E-value: 3.67e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAkGGLEVAGKRYKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06337 1 KIGRVSPLTGPLAAFGEADPWVLEQIREAFAD-GGIKVGGKKYPVEIVVRDSQSDPNRAGEAARDLILRDKVDLMLASGT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKV-IIMTLG-----FTAKALSPEKP--YSFRPNLTTEETsYPSIVWLVNHFKL-KKVAALFPNDES 176
Cdd:cd06337 80 PDTVNPVADQCEANGVpCISTDApwqawFFGRGGDPAKGfkWTFHFFWGLEDI-AANFLGMWDQVPTnKVVGLLWPNDPD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 177 GQQIARDLEQAYAKAGSSMsskefferqrVD--MVPLLTRMMAAGIDAIELDGNSPATAGMIV-------KQARELGFKg 247
Cdd:cd06337 159 GTAFADAFLGLPAAAGYTL----------VDpgRFPPGTDDFSSIINAFKKAGVEIVTGVMIPpdfatfwRQAAQQGFK- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 248 PIVRNGGPAT--PEIVAVAGKAAtEGMM-----------VSSLTdpdNKAVAEYAQRYQKKYNKKMN---GFSPAFYDgt 311
Cdd:cd06337 228 PKVVTIGKALlfPSAVAALGDLG-DGLStevwwspahpfKSSLT---GQTAAELADAYEKATGKQWTqplGYAHALFE-- 301
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1567725627 312 hMLFKAMQDAGTVtDSEKVRNALEAIKnYPGIQGTLNWGGKAKYGI 357
Cdd:cd06337 302 -VAVDALKRAGSP-DDEAVRAALADTD-LDTIVGPVDFTSGPVPNV 344
|
|
| PBP1_amide_urea_BP-like |
cd06356 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
26-352 |
8.11e-16 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the type 1 periplasmic-binding proteins that are predicted to have a function similar to that of an active transport system for short chain amides and/or urea in bacteria and Archaea, by sequence comparison and phylogenetic analysis.
Pssm-ID: 380579 [Multi-domain] Cd Length: 334 Bit Score: 77.73 E-value: 8.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLEvaGKryKVQLVPYD-----DKYQSgdavtATNRLLSDDGVKYI 100
Cdd:cd06356 1 KIGSIFDLSGGLNIYGKPMVHAMKLAVEEINAAGGLL--GR--QIELVAYDtqsdmQKYTQ-----YAQQLILRDKVDVV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 101 IGPMGSAPALAVQPVTEPGKVIIM--TL---GFTAKalspekpYSFRPNLTTEETSYPSIVWLVNHFKlKKVAALFPNDE 175
Cdd:cd06356 72 FGGITSASREAIRPILRRNKILYFynTQyegGVCDK-------NTFCTGSTPEQQVSPLIEWAIKKYG-KKVYIIAADYN 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 176 SGqQIARDLEQAYAKA-GSSMSSKEFFERQRVDMVPLLTRMMAAGIDAI--ELDGNSP-------ATAGMIVKQarelgf 245
Cdd:cd06356 144 FG-QISADWVKKYAKKnGGEVVGEEFFPLDVTDFGPTIQKIQAAKPDFVvsLLVGGNHisfyrqwAAAGLKKKI------ 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 246 kgPIVRNGGPATPEIVAVAGKaATEGMMVSS--LTDPDNKAVAEYAQRYQKKYNKKMNGFSPAF--YDGTHMLFKAMQDA 321
Cdd:cd06356 217 --PIVSTVFGAGNEHKVLSPP-ELEGMYVSYsyFEELDTPANKAFVAKWRAKYGDEPYINQEAVgvYNAVYLWAEAVEKA 293
|
330 340 350
....*....|....*....|....*....|.
gi 1567725627 322 GTvTDSEKVRNALEAIKNYPGIQGTLNWGGK 352
Cdd:cd06356 294 GS-TEREAVIAALESGISFDGPSGTVTVDPK 323
|
|
| PBP1_NHase |
cd06358 |
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively ... |
26-335 |
1.63e-15 |
|
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides; This group includes the type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides, which are subsequently converted by amidases to yield free carboxylic acids and ammonia. NHases from bacteria and fungi have been purified and characterized. In Rhodococcus sp., the nitrile hydratase operon consists of six genes encoding NHase regulator 2, NHase regulator 1, amidase, NHase alpha subunit, NHase beta subunit, and NHase activator. The operon produces a constitutive hydratase that has a broad substrate spectrum: aliphatic and aromatic nitriles, mononitriles and dinitriles, hydroxynitriles and amino-nitriles, and a constitutive amidase of equally low substrate specificity. NHases are metalloenzymes containing either cobalt or iron, and therefore can be classified into two subgroups: ferric NHases and cobalt NHases.
Pssm-ID: 380581 [Multi-domain] Cd Length: 333 Bit Score: 76.86 E-value: 1.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06358 1 RIGLLIPLSGPAGLWGPSCEACAELAAAEINAAGG--ILGR--EVELVLIDAGGPPAEVAAAARRLVDDGAVDAIVGMHT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTePGKViimtlgftakalspekPYSFRPN--------------LTTEETSYPSIVWLVNHFKLKKVaALF 171
Cdd:cd06358 77 SAVRQALANAV-GGRV----------------PYVYTPLyeggertpgvyaigETPEEQLRPALRWLADERRVRRW-FLV 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 172 PNDES-GQQIARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDA--IELDGNSpatAGMIVKQARELGFKGP 248
Cdd:cd06358 139 GNDYVwPRASHAAARRYIARLGGEVVGERFVPLGEDDFERVLARIRASRPDAvlISLVGQD---AVDFNRAFAAAGLAGR 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 249 IVRNgGPATPEIVAVA-GKAATEGMMVSS-----LTDPDNKAVAEyaqRYQKKY---NKKMNGFSPAFYDGTHMLFKAMQ 319
Cdd:cd06358 216 ILRL-SPAIDENVLLAiGADATENLYSASgyfasLRTAANLAFLE---RYHAAFgdrAPPLNALGESCYEGVHFLAALAR 291
|
330
....*....|....*.
gi 1567725627 320 DAGTvTDSEKVRNALE 335
Cdd:cd06358 292 RAGS-LDVRALAAAAE 306
|
|
| PBP1_Nba-like |
cd06359 |
type 1 periplasmic binding component of active transport systems predicted to be involved in ... |
26-359 |
1.84e-15 |
|
type 1 periplasmic binding component of active transport systems predicted to be involved in 2-nitrobenzoic acid degradation pathway; This group includes the type 1 periplasmic binding component of active transport systems that are predicted to be involved in 2-nitrobenzoic acid degradation pathway; their substrate specificities are not well characterized.
Pssm-ID: 380582 [Multi-domain] Cd Length: 333 Bit Score: 76.52 E-value: 1.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAK-GGLEVagkrykvQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPM 104
Cdd:cd06359 1 KIGFITTLSGPAAVLGQDMRDGFNLALEQLGGKlGGLPV-------EVVVEDDQLKPDVAKQAAERLIERDKVDFVTGII 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 105 GSAPALAVQPVTEPGKVIIMTLGFTAKALSPEK--PYSFrpnltteETSYPSIVW------LVNHFKLKKVAALFPNDES 176
Cdd:cd06359 74 FSNVMLAVVKPVVDSKVFYISANAGPSDLAGKGcnPNFF-------VTSWQNDQLheaagkYANDKGYKRVYLLAPNYQA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 177 GQQIARDLEQAYAkagSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELdgNSPATAGM-IVKQARELGFKG--PIVRNG 253
Cdd:cd06359 147 GKDALAGFKRTYK---GEVVGEIYTPLGQLDFSAELAQIRAAKPDAVFA--FYPGGMGVnFVKQYAQAGLKKkiPLYTVG 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 254 GPATPEIVAVAGKAAtEGMMVSS-----LTDPDNKA-VAEyaqrYQKKYNKKMNGFSPAFYDGTHMLFKAMQDA-GTVTD 326
Cdd:cd06359 222 TLDDEDLLPAMGDAA-LGVLSVSqwspdLDNPENKRfVAA----FRKKYGRPPSNYAAQGYDAALLIDAAVKAVgGDLSD 296
|
330 340 350
....*....|....*....|....*....|...
gi 1567725627 327 SEKVRNALEAIkNYPGIQGTLnwggkaKYGINH 359
Cdd:cd06359 297 KDALRAALRKA-DFKSVRGAF------RFNNNQ 322
|
|
| PBP1_ABC_HAAT-like |
cd19985 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-314 |
5.16e-14 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380640 [Multi-domain] Cd Length: 321 Bit Score: 72.31 E-value: 5.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLEvaGKryKVQLVPYDDKyQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd19985 1 HIAVVGPMSGKSASKGKSMLRGAELYIDQINAAGGIN--GK--KVKLDVFDDQ-NDPDAARKAAQIIVSDKALAVIGHYY 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFRPNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIARDLE 185
Cdd:cd19985 76 SSASIAAGKIYKKAGIPAITPSATADAVTRDNPWYFRVIFNDSLQGRFLANYAKKVLKKDKVSIIYEEDSYGKSLASVFE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 186 QAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELDG-----NSPATAGMIVKQARELGFKGPIVrngGPAT--- 257
Cdd:cd19985 156 ATARALGLKVLKKWSFDTDSSQLDQNLDQIVDELKKAPDEPGviflaTHADEGAKLIKKLRDAGLKAPII---GPDSlas 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1567725627 258 ----------PEIVAVAGKaATEGMMVSS--LTDPDNKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHML 314
Cdd:cd19985 233 esfaqgfaeyPEEKEEPGY-YTDGIYATSpfIFDIANEKAQKFRDTYQKRYGEEPSWIAAFAYDAAMLA 300
|
|
| PBP1_SBP-like |
cd06327 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
26-338 |
1.08e-13 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380550 [Multi-domain] Cd Length: 336 Bit Score: 71.45 E-value: 1.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAW-GQALLYGAELAADDVnakgGLEVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPM 104
Cdd:cd06327 1 RIGVLTDLSGVYADLsGPGSVEAAKMAVEDF----GGKVLGR--PIEVVSADHQNKPDVASAIAREWYDRDGVDAIVDVP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 105 GSAPALAVQPVT-EPGKVII----MTLGFTAKALSpekPYSFRPNLTTEETSYPSIVWLVNHfKLKKVAALFPNDESGQQ 179
Cdd:cd06327 75 NSAVALAVQKLAkEKKKIAIvtgaGSSDLTGKACS---PYGVHWAYDTYALARGTVKALVKQ-GGKSWFFITADYAFGHS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 180 IARDLEQAYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIELdGNSPATAGMIVKQARELGFKGPIVRNGGPAT-- 257
Cdd:cd06327 151 LEADATAAVKAAGGKVVGSVRHPLGTTDFSSFLLQAQASGADVIAL-ANAGADLVNAVKQAREFGLTDGGQKLAALLLfi 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 258 PEIVAvAGKAATEGMMVSSLTDPD-NKAVAEYAQRYQKKYNKKMNGFSPAFYDGTHMLFKAMQDAGTvTDSEKVRNALEA 336
Cdd:cd06327 230 TDIHA-LGLDAAQGLYLTTAFYWDrDDATRAWAKRFFARTGKMPTMLQAGVYSAVLHYLKAVKAAGT-DDADAVVAKMRE 307
|
..
gi 1567725627 337 IK 338
Cdd:cd06327 308 MP 309
|
|
| PBP1_AmiC |
cd06357 |
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding ... |
26-334 |
1.30e-12 |
|
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family; This group includes the periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family. AmiC controls expression of the amidase operon by the ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon are induced.
Pssm-ID: 380580 [Multi-domain] Cd Length: 357 Bit Score: 68.37 E-value: 1.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06357 1 RVGLLFSQTGVTAIIEQSMLNGALLAIEEINAAGG--VNGR--PIEPVVYDPASDPDRYRELAERLLLEDGVRHIFGCYT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEPGKVIIM--TL--GFTAkalSPEKPYS-FRPNltteETSYPSIVWLVNHFKlKKVAAL-----FPNdE 175
Cdd:cd06357 77 SASRKAVLPVVERHNALLWypTPyeGFEY---SPNVIYTgAVPN----QHLLPLARYLLAHFG-KRVFLVgsnyvYPW-E 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 176 SgQQIARDLeqaYAKAGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAI--ELDGNSpATAgmIVKQARELGFKG---PIV 250
Cdd:cd06357 148 S-NRVAREL---IEASGGEVVGERYVPLGDTDFAEIIEEIKSLKPDVVfsTLVGDS-IYA--FYRAYAEAGLDPadmPIA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 251 rngGPAT--PEIVAVAGKAAtEGMMVS-----SLTDPDNKA-VAEYAQRYQKkyNKKMNGFSPAFYDGTHMLFKAMQDAG 322
Cdd:cd06357 221 ---SLTTseAEVAAIGAEAA-AGHYTSapyfqSIDTPENRAfVEAYRARFGD--DAVTSAVAEAAYFQVHLLARAIERAG 294
|
330
....*....|..
gi 1567725627 323 TVtDSEKVRNAL 334
Cdd:cd06357 295 SD-DPEAIRAAL 305
|
|
| PBP1_glutamate_receptors-like |
cd06269 |
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl ... |
26-310 |
1.20e-10 |
|
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as natriuretic peptide receptors (NPRs), and N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of ionotropic glutamate rece; This CD represents the ligand-binding domain of the family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs), and the N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the ionotropic glutamate receptors, all of which are structurally similar and related to the periplasmic-binding fold type 1 family. The family C GPCRs consists of metabotropic glutamate receptor (mGluR), a calcium-sensing receptor (CaSR), gamma-aminobutyric acid receptor (GABAbR), the promiscuous L-alpha-amino acid receptor GPR6A, families of taste and pheromone receptors, and orphan receptors. Truncated splicing variants of the orphan receptors are not included in this CD. The family C GPCRs are activated by endogenous agonists such as amino acids, ions, and sugar based molecules. Their amino terminal ligand-binding region is homologous to the bacterial leucine-isoleucine-valine binding protein (LIVBP) and a leucine binding protein (LBP). The ionotropic glutamate receptors (iGluRs) have an integral ion channel and are subdivided into three major groups based on their pharmacology and structural similarities: NMDA receptors, AMPA receptors, and kainate receptors. The family of membrane bound guanylyl cyclases is further divided into three subfamilies: the ANP receptor (GC-A)/C-type natriuretic peptide receptor (GC-B), the heat-stable enterotoxin receptor (GC-C)/sensory organ specific membrane GCs such as retinal receptors (GC-E, GC-F), and olfactory receptors (GC-D and GC-G).
Pssm-ID: 380493 [Multi-domain] Cd Length: 332 Bit Score: 62.05 E-value: 1.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGA---GAAWGQALlygaELAADDVNAKGGLevaGKRYKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIG 102
Cdd:cd06269 1 TIGALLPVHDYlesGAKVLPAF----ELALSDVNSRPDL---LPKTTLGLAIRDSECNPTQALLSACDLLAAAKVVAILG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 103 PMGSAPALAVQPVTEPGKVIIMTLGFTAKALS--PEKPYSFRpnlTTEETSY--PSIVWLVNHFKLKKVAALFPNDESGQ 178
Cdd:cd06269 74 PGCSASAAPVANLARHWDIPVLSYGATAPGLSdkSRYAYFLR---TVPPDSKqaDAMLALVRRLGWNKVVLIYSDDEYGE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 179 QIARDLEQAYAKAGSSMSSKEFFERQRVDMVP-LLTRMMAAGIDAIELDGnSPATAGMIVKQARELGFKGP----IVRNG 253
Cdd:cd06269 151 FGLEGLEELFQEKGGLITSRQSFDENKDDDLTkLLRNLRDTEARVIILLA-SPDTARSLMLEAKRLDMTSKdyvwFVIDG 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1567725627 254 GPATPEIVAVAGKAATEGMMVSSLTDPDNKAVAEY--------AQRYQKK-YNKKMNGFSPAFYDG 310
Cdd:cd06269 230 EASSSDEHGDEARQAAEGAITVTLIFPVVKEFLKFsmelklksSKRKQGLnEEYELNNFAAFFYDA 295
|
|
| PBP1_GABAb_receptor |
cd06366 |
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for ... |
27-310 |
3.84e-10 |
|
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA); Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380589 [Multi-domain] Cd Length: 404 Bit Score: 61.11 E-value: 3.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 27 IGAVVTLSGAGAAW-GQALLYGAELAADDVNAKGGLEvagKRYKVQLVPYDDKYQSGDAVTATNRLLS-DDGVKYIIGPM 104
Cdd:cd06366 2 IGGLFPLSGSKGWWgGAGILPAAEMALEHINNRSDIL---PGYNLELIWNDTQCDPGLGLKALYDLLYtPPPKVMLLGPG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 105 GSAPALAVQPVTEPGKVIIMTLGFTAKALSPEK--PYSFRpNLTTEETSYPSIVWLVNHFKLKKVAALFPNDESGQQIAR 182
Cdd:cd06366 79 CSSVTEPVAEASKYWNLVQLSYAATSPALSDRKryPYFFR-TVPSDTAFNPARIALLKHFGWKRVATIYQNDEVFSSTAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 183 DLEQAYAKAGSSMSSKEFFerQRVDMVPLLTRMMAAgiDA-IELDGNSPATAGMIVKQARELGFKGP------------- 248
Cdd:cd06366 158 DLEELLEEANITIVATESF--SSEDPTDQLENLKEK--DArIIIGLFYEDAARKVFCEAYKLGMYGPkyvwilpgwyddn 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1567725627 249 ---IVRNGGPATPE--IVAVAGKAATEGMMVSSLTDP--DNKAVAEYAQRYQK---KYNKKMNGFSPAFYDG 310
Cdd:cd06366 234 wwdVPDNDVNCTPEqmLEALEGHFSTELLPLNPDNTKtiSGLTAQEFLKEYLErlsNSNYTGSPYAPFAYDA 305
|
|
| PBP1_ABC_transporter_GPCR_C-like |
cd04509 |
Family C of G-protein coupled receptors and their close homologs, the type 1 ... |
26-247 |
9.34e-10 |
|
Family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems; This CD includes members of the family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems. The family C GPCR includes glutamate/glycine-gated ion channels such as the NMDA receptor, G-protein-coupled receptors, metabotropic glutamate, GABA-B, calcium sensing, pheromone receptors, and atrial natriuretic peptide-guanylate cyclase receptors. The glutamate receptors that form cation-selective ion channels, iGluR, can be classified into three different subgroups according to their binding-affinity for the agonists NMDA (N-methyl-D-asparate), AMPA (alpha-amino-3-dihydro-5-methyl-3-oxo-4-isoxazolepropionic acid), and kainate. L-glutamate is a major neurotransmitter in the brain of vertebrates and acts through either mGluRs or iGluRs. mGluRs subunits possess seven transmembrane segments and a large N-terminal extracellular domain. ABC-type leucine-isoleucine-valine binding protein (LIVBP) is a bacterial periplasmic binding protein that has homology with the amino-terminal domain of the glutamate-receptor ion channels (iGluRs). The extracellular regions of iGluRs are made of two PBP-like domains in tandem, a LIVBP-like domain that constitutes the N terminus (included in this model) followed by a domain related to lysine-arginine-ornithine-binding protein (LAOBP) that belongs to the type 2 periplasmic binding fold protein superfamily. The uncharacterized periplasmic components of various ABC-type transport systems are also included in this family.
Pssm-ID: 380490 Cd Length: 306 Bit Score: 59.24 E-value: 9.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAA----------WGQALLYGAELAADDVNAKGGLEvagKRYKVQLVPYDDKYQSGDAVTATNRLLSD- 94
Cdd:cd04509 1 KVGVLFAVHGKGPSgvpcgdivaqYGIQRFEAMEQALDDINADPNLL---PNNTLGIVIYDDCCDPKQALEQSNKFVNDl 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 95 ---------------------DGVKYIIGPMGSAPALAVQPVTEPGKVIIMTLGFTAKALSPEKPYSFRPNLTTEET-SY 152
Cdd:cd04509 78 iqkdtsdvrctngeppvfvkpEGIKGVIGHLCSSVTIPVSNILELFGIPQITYAATAPELSDDRGYQLFLRVVPLDSdQA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 153 PSIVWLVNHFKLKKVAALFPNDESGQQIARDLEQAYAKAGSSM--SSKEFFERQRVDMVPLLTRMMAA-GIDAIELDGNS 229
Cdd:cd04509 158 PAMADIVKEKVWQYVSIVHDEGQYGEGGARAFQDGLKKGGLCIafSDGITAGEKTKDFDRLVARLKKEnNIRFVVYFGYH 237
|
250
....*....|....*...
gi 1567725627 230 PaTAGMIVKQARELGFKG 247
Cdd:cd04509 238 P-EMGQILRAARRAGLVG 254
|
|
| Peripla_BP_5 |
pfam13433 |
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic ... |
25-372 |
7.22e-08 |
|
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic binding proteins.
Pssm-ID: 463875 [Multi-domain] Cd Length: 363 Bit Score: 53.75 E-value: 7.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 25 LKIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGleVAGKryKVQLVPYDDkyQSGDAVTAT--NRLLSDDGVKYIIG 102
Cdd:pfam13433 1 IKVGVLHSLTGTMAISERSLKDATLMAIEEINAAGG--VLGR--KIEPVVVDP--ASDWPLFAEkaRKLIDQDKVRVVFG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 103 PMGSAPALAVQPVTE--------P--------GKVIIMTlGFTakalspekpysfrPNltteETSYPSIVWLVNHFKlKK 166
Cdd:pfam13433 75 CWTSASRKAVLPVFErhngllfyPvqyegfesSRNIFYT-GAA-------------PN----QQAIPAVDYLLSELG-KR 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 167 VAAL-----FPNdESGqQIARDLEQA---------YAKAGSSmsskefferqrvDMVPLLTRMMAAGIDAI--ELDGNSp 230
Cdd:pfam13433 136 FFLVgsdyvYPR-TTN-RILRAYLKAkggevvgerYLPLGSS------------DWQSIVAKIKAAGPDVVfsTINGDS- 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 231 atAGMIVKQARELGFKG---PIVrnGGPATPEIVAVAGKAATEGMMVS-----SLTDPDNKAvaeYAQRYQKKYNKKM-- 300
Cdd:pfam13433 201 --NVAFYRALRAAGITAediPVM--SFSVAEEELAGMGPEPLVGHLAAwnyfqSLDTPENKA---FVAAFKARYGDDRvt 273
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1567725627 301 NGFSPAFYDGTHMLFKAMQDAGTvTDSEKVRNALEAIKnYPGIQGTLnwggkAKYGINHQIESPFFISEVKD 372
Cdd:pfam13433 274 NDPMEAAYIGVHLWAQAVEKAGT-DDPDAVRQAMLGQE-FDAPQGPV-----KIDPENHHTWKPVRIGRIRA 338
|
|
| PBP1_GABAb_receptor_plant |
cd19990 |
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close ... |
26-198 |
1.32e-05 |
|
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants; This group includes the ligand-binding domain of Arabidopsis thaliana glutamate receptors, which have sequence similarity with animal ionotropic glutamate receptor and its close homologs in other plants. The ligand-binding domain of GABAb receptors are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380645 [Multi-domain] Cd Length: 373 Bit Score: 46.84 E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTL-SGAGAAWGQALlygaELAADDVNAKGGlevaGKRYKVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPM 104
Cdd:cd19990 1 KIGAILDLnSRVGKEAKVAI----EMAVSDFNSDSS----SYGTKLVLHVRDSKGDPLQAASAALDLIKNKKVEAIIGPQ 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 105 GSAPALAVQPVTEPGKVIIMTLGFTAKALSPEK-PYSFRpnlTTEETSYP--SIVWLVNHFKLKKVAALFPNDESGQQIA 181
Cdd:cd19990 73 TSEEASFVAELGNKAQVPIISFSATSPTLSSLRwPFFIR---MTHNDSSQmkAIAAIVQSYGWRRVVLIYEDDDYGSGII 149
|
170
....*....|....*..
gi 1567725627 182 RDLEQAYAKAGSSMSSK 198
Cdd:cd19990 150 PYLSDALQEVGSRIEYR 166
|
|
| PBP1_FmdD-like |
cd06355 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
26-373 |
3.88e-04 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF), found in Methylophilus methylotrophus, and its homologs from other bacteria. FmdD, a type 1 periplasmic binding protein, is induced by short-chain amides and urea and repressed by excess ammonia, while FmdE and FmdF are hydrophobic transmembrane proteins. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380578 [Multi-domain] Cd Length: 347 Bit Score: 42.18 E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 26 KIGAVVTLSGAGAAWGQALLYGAELAADDVNAKGGLEvaGKRykVQLVPYDDKYQSGDAVTATNRLLSDDGVKYIIGPMG 105
Cdd:cd06355 1 KVGILHSLSGTMAISERPLVDATLLAIDEINAAGGLL--GRK--IEPVIEDGASDWPTFAEKAEKLITQDKVAVIFGCWT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 106 SAPALAVQPVTEpgkviimtlgfTAKAL------------SPEKPYS-FRPNLTTEetsyPSIVWLVNHFKlKKVAAL-- 170
Cdd:cd06355 77 SASRKAVLPVIE-----------KYNGLlfypvqyegleqSPNIVYTgATPNQQIL----PAIDWLLENLG-KRFFLVgs 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 171 ---FPNDESgqQIARDLEQAYakaGSSMSSKEFFERQRVDMVPLLTRMMAAGIDAIEL----DGNSPatagmIVKQAREL 243
Cdd:cd06355 141 dyvFPRTAN--KIIRDQLKAL---GGEVVGEEYVPLGGTDFDAIVAKIKAFKPDVIVNtlngDSNIA-----FFKQLAAA 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 244 GFKG---PIVrnGGPATPEIVAVAGKAATEGMMVS-----SLTDPDNKAVAEyaqRYQKKYNKKMNGFSP--AFYDGTHM 313
Cdd:cd06355 211 GITAsdlPVL--SFSVSEAELRAIGPEELAGHYAAwnyfqSLDTPENQAFVE---AFKAKYGADRVTSDPmeAAYLGVYL 285
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 314 LFKAMQDAGTvTDSEKVRNALEAIKnYPGIQGTLnwggkAKYGINHQIESPFFISEVKDG 373
Cdd:cd06355 286 WAQAVEKAGS-FDPDAVRAALKGQS-FEAPGGTV-----TVDPENHHLWKPVRIGKVQAD 338
|
|
| PBP1_NPR-like |
cd06373 |
Ligand binding domain of natriuretic peptide receptor (NPR) family; Ligand binding domain of ... |
49-346 |
3.23e-03 |
|
Ligand binding domain of natriuretic peptide receptor (NPR) family; Ligand binding domain of natriuretic peptide receptor (NPR) family which consists of three different subtypes: type A natriuretic peptide receptor (NPR-A, or GC-A), type B natriuretic peptide receptors (NPR-B, or GC-B), and type C natriuretic peptide receptor (NPR-C). There are three types of natriuretic peptide (NP) ligands specific to the receptors: atrial NP (ANP), brain or B-type NP (BNP), and C-type NP (CNP). The NP family is thought to have arisen through gene duplication during evolution and plays an essential role in cardiovascular and body fluid homeostasis. ANP and BNP bind mainly to NPR-A, while CNP binds specifically to NPR-B. Both NPR-A and NPR-B have guanylyl cyclase catalytic activity and produces intracellular secondary messenger cGMP in response to peptide-ligand binding. Consequently, the NPR-A activation results in vasodilation and inhibition of vascular smooth muscle cell proliferation. NPR-C acts as the receptor for all the three members of NP family, and functions as a clearance receptor. Unlike NPR-A and -B, NPR-C lacks an intracellular guanylyl cyclase domain and is thought to exert biological actions by sequestration of released natriuretic peptides and/or inhibition of adenylyl cyclase.
Pssm-ID: 380596 [Multi-domain] Cd Length: 394 Bit Score: 39.18 E-value: 3.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 49 ELAADDVNAKGGLEvaGKRYKVQLVpyDDKYQSGDAVTATNRLLSDDGVKYIIGPMGSAPALAVQPVTEPGKVIIMTLGF 128
Cdd:cd06373 24 ELALRRVERRGFLP--GWRFQVHYR--DTKCSDTLAPLAAVDLYCAKKVDVFLGPVCEYALAPVARYAGHWNVPVLTAGG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 129 TAKALSPEKPYsfrPNLTTEETSYPSIVWLV----NHFKLKKVAALFPNDESGQQIARD----LEQAYAKAGSSMSS--K 198
Cdd:cd06373 100 LAAGFDDKTEY---PLLTRMGGSYVKLGEFVltllRHFGWRRVALLYHDNLRRKAGNSNcyftLEGIFNALTGERDSihK 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 199 EF--FERQRVDMVPLLTRMMAAGidAIELDGNSPATAGMIVKQARELGF-------------------KGPIVRNGgpAT 257
Cdd:cd06373 177 SFdeFDETKDDFEILLKRVSNSA--RIVILCASPDTVREIMLAAHELGMingeyvffnidlfsssskgARPWYREN--DT 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 258 PEIVAVAgKAATEGMMVSSLTDPDNKavaEYAQ-------RYQKKYNK------KMNGFSPAFYDG----THMLFKAMQD 320
Cdd:cd06373 253 DERNEKA-RKAYRALLTVTLRRPDSP---EYRNfseevkeRAKEKYNYftygdeEVNSFVGAFHDAvllyALALNETLAE 328
|
330 340 350
....*....|....*....|....*....|
gi 1567725627 321 AGTVTD----SEKVRNaleaiKNYPGIQGT 346
Cdd:cd06373 329 GGSPRNgteiTERMWN-----RTFEGITGN 353
|
|
| PBP1_iGluR_Kainate |
cd06382 |
N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the kainate ... |
49-244 |
8.18e-03 |
|
N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the kainate receptors; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the kainate receptors, non-NMDA ionotropic receptors which respond to the neurotransmitter glutamate. While this N-terminal domain belongs to the periplasmic-binding fold type 1 superfamily, the glutamate-binding domain of the iGluR is structurally homologous to the periplasmic-binding fold type 2. The LIVBP-like domain of iGluRs is thought to play a role in the initial assembly of iGluR subunits, but it is not well understood how this domain is arranged and functions in intact iGluR. Kainate receptors have five subunits, GluR5, GluR6, GluR7, KA1 and KA2, which are structurally similar to AMPA and NMDA subunits of ionotropic glutamate receptors. KA1 and KA2 subunits can only form functional receptors with one of the GluR5-7 subunits. Moreover, GluR5-7 can also form functional homomeric receptor channels activated by kainate and glutamate when expressed in heterologous systems. Kainate receptors are involved in excitatory neurotransmission by activating postsynaptic receptors and in inhibitory neurotransmission by modulating release of the inhibitory neurotransmitter GABA through a presynaptic mechanism. Kainate receptors are closely related to AMAP receptors. In contrast of AMPA receptors, kainate receptors play only a minor role in signaling at synapses and their function is not well defined.
Pssm-ID: 380605 Cd Length: 335 Bit Score: 37.97 E-value: 8.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 49 ELAADDVNAKGGLEVAGKRYKVQLVPYDDKYQSGDAVTAtnrlLSDDGVKYIIGPMGSAPALAVQPVTE----PgkVIIM 124
Cdd:cd06382 18 KYAVDRINRERTLPNTKLVPDIERVPRDDSFEASKKVCE----LLEEGVAAIFGPSSPSSSDIVQSICDaleiP--HIET 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567725627 125 TLGFTakaLSPEKPYSFrpNLtteetsYPS-------IVWLVNHFKLKKVAALFPNDEsGQQIARDLEQAYAKAGSSMSS 197
Cdd:cd06382 92 RWDPK---ESNRDTFTI--NL------YPDpdalskaYADLVKSLNWKSFTILYEDDE-GLIRLQELLKLPKPKDIPITV 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1567725627 198 KEFfeRQRVDMVPLLTRMMAAGIDAIELDGnSPATAGMIVKQARELG 244
Cdd:cd06382 160 RQL--DPGDDYRPVLKEIKKSGETRIILDC-SPDRLVDVLKQAQQVG 203
|
|
| |
