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Conserved domains on  [gi|1580982069|ref|WP_130574490|]
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MULTISPECIES: IS3 family transposase [Enterobacterales]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
13-377 4.50e-150

IS3 family transposase;


:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 428.52  E-value: 4.50e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  13 EFKQEAVALVTEQGYSVVEAAQAVGVNPNQIYAWKKHFE------DQASGVALSDDERAELRKLRAENKRLRMEKEILKK 86
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRgggeaaDAGRLKELLTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  87 ASGLLRqgNEINFKFIHQARQEgYPVGLSCKTLGLSRSGYYAWDKRPAQLITEDTLMLYRTAKQLFKDSRESLGSRELMK 166
Cdd:NF033516   81 ARKLLR--PAVKYALIDALRGE-YSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 167 KLNQHGFAIGRYKTRSIMQRLNLVVRQRVAYKV-TTQRDKRHLAAPNLVSMDFNPERPNQVWAGDITYLKTAQGWMYLSV 245
Cdd:NF033516  158 LLRREGIRVNHKRVYRLMRELGLLARRRRKRRPyTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 246 VMDLYSRRIVGWSISKRMTTDLVLKSLQQAYWLRKHPKGVIFHSDRGSQYTSKKLRKALVRMGIKQSMGDTGACWDNAVV 325
Cdd:NF033516  238 VLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVA 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1580982069 326 ERFFGSLKHDWILKVHHATYEEMVADVTAYMKYYNVKRLHTANGDVSPVEYE 377
Cdd:NF033516  318 ESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
13-377 4.50e-150

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 428.52  E-value: 4.50e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  13 EFKQEAVALVTEQGYSVVEAAQAVGVNPNQIYAWKKHFE------DQASGVALSDDERAELRKLRAENKRLRMEKEILKK 86
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRgggeaaDAGRLKELLTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  87 ASGLLRqgNEINFKFIHQARQEgYPVGLSCKTLGLSRSGYYAWDKRPAQLITEDTLMLYRTAKQLFKDSRESLGSRELMK 166
Cdd:NF033516   81 ARKLLR--PAVKYALIDALRGE-YSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 167 KLNQHGFAIGRYKTRSIMQRLNLVVRQRVAYKV-TTQRDKRHLAAPNLVSMDFNPERPNQVWAGDITYLKTAQGWMYLSV 245
Cdd:NF033516  158 LLRREGIRVNHKRVYRLMRELGLLARRRRKRRPyTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 246 VMDLYSRRIVGWSISKRMTTDLVLKSLQQAYWLRKHPKGVIFHSDRGSQYTSKKLRKALVRMGIKQSMGDTGACWDNAVV 325
Cdd:NF033516  238 VLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVA 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1580982069 326 ERFFGSLKHDWILKVHHATYEEMVADVTAYMKYYNVKRLHTANGDVSPVEYE 377
Cdd:NF033516  318 ESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
63-382 2.28e-97

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 292.44  E-value: 2.28e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  63 ERAELRKLRAENKRLRMEKEILKKASGLLRQGNEINFKFIHQARQEgypvglscktlgLSRSGYYAWDKRPAQLITEDTL 142
Cdd:COG2801     4 EEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRR------------RARSRRRRRLRRPRSYRADEDA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 143 MLYRTAKQLFKDSReSLGSRELMKKLNQHGFAIGRYKTRSIMQRLNLVVRQRVAYKVTTQRDKRHLAAPNLVsmdFNPER 222
Cdd:COG2801    72 ELLERIKEIFAESP-RYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYTTYSGHGGPIAPNLL---FTATA 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 223 PNQVWAGDITYLKTAQGWMYLSVVMDLYSRRIVGWSISKRMTTDLVLKSLQQAYWLRKHPKGVIFHSDRGSQYTSKKLRK 302
Cdd:COG2801   148 PNQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYTSKAYQE 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 303 ALVRMGIKQSMGDTGACWDNAVVERFFGSLKHDWILKVHHATYEEMVADVTAYMKYYNVKRLHTANGDVSPVEYENYQLK 382
Cdd:COG2801   228 LLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIEFYNHERPHSSLGYLTPAEYEKQLAA 307
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 119-384 1.05e-78

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 243.62  E-value: 1.05e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 119 LGLSRSGYYAW-------DKRPAQLITEDtlMLYRTAKQLFKDSRESLGSRELMKKLNQHGFAIGRYKTRSIMQRLNLVV 191
Cdd:PHA02517    1 LGIAPSTYYRCqqqrhhpDKRRARAQHDD--WLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 192 RQRVAYKVTTQRDKrHLAAPNLVSMDFNPERPNQVWAGDITYLKTAQGWMYLSVVMDLYSRRIVGWSISKRMTTDLVLKS 271
Cdd:PHA02517   79 VLRGKKVRTTISRK-AVAAPDRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 272 LQQAYWLRKHPKGVIFHSDRGSQYTSKKLRKALVRMGIKQSMGDTGACWDNAVVERFFGSLKHDWILKVHHATYEEMVAD 351
Cdd:PHA02517  158 LEQALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELA 237

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1580982069 352 VTAYMKYYNVKRLHTANGDVSPVEYENYQLKVS 384
Cdd:PHA02517  238 TLEWVAWYNNRRLHERLGYTPPAEAEKAYYASI 270
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 223-319 1.75e-30

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 112.41  E-value: 1.75e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 223 PNQVWAGDITYLK--TAQGWMYLSVVMDLYSRRIVGWSISKRMTTDLVLKSLQQAYWLRkHPKGVIFHSDRGSQYTSKKL 300
Cdd:pfam00665   1 PNQLWQGDFTYIRipGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFR-GGVPLIIHSDNGSEYTSKAF 79

                          90
                  ....*....|....*....
gi 1580982069 301 RKALVRMGIKQSMGDTGAC 319
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
 99-375 7.27e-20

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 88.42  E-value: 7.27e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  99 FKFIHQARQEGYPVGLSCKTLGLSRSGYYAW------------------DKRPAQLITEDT----LMLYRTAKqlfkdsr 156
Cdd:NF033577    3 LELVRLVLEDGWSVREAARRFGISRKTVYKWlkryraggeeglidrsrrPHRSPRRTSPETeariLALRRELR------- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 157 esLGSRELMKKLNQHGFAIGRYKTRSIMQRLNLVVRQRVayKVTTQRDKRhlaapnlvsmdFNPERPNQVWAGDITYLKT 236
Cdd:NF033577   76 --LGPRRIAYELERQGPGVSRSTVHRILRRHGLSRLRAL--DRKTGKVKR-----------YERAHPGELWHIDIKKLGR 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 237 AQ--GWMYLSVVMDLYSRRIVGwSISKRMTTDLVLKSLQQAYwlRKHPKGV--IFhSDRGSQYTSKK--LRKALVRMGIK 310
Cdd:NF033577  141 IPdvGRLYLHTAIDDHSRFAYA-ELYPDETAETAADFLRRAF--AEHGIPIrrVL-TDNGSEFRSRAhgFELALAELGIE 216

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1580982069 311 QSMGDTGACWDNAVVERFFGSLKHDWILKVHHATYEEMVADVTAYMKYYNVKRLHTANGDVSPVE 375
Cdd:NF033577  217 HRRTRPYHPQTNGKVERFHRTLKDEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPAE 281
transpos_IS630 NF033545
IS630 family transposase;
15-73 8.17e-03

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 37.62  E-value: 8.17e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1580982069  15 KQEAVALVTEQGYSVVEAAQAVGVNPNQIYAWKKHFEDQasGVA-------------LSDDERAELRKLRAE 73
Cdd:NF033545    1 RRARILLLAAEGLSITEIAERLGVSRSTVYRWLKRFNEG--GLEglldkprpgrprkLLSEQQAELLALLLE 70
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
13-377 4.50e-150

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 428.52  E-value: 4.50e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  13 EFKQEAVALVTEQGYSVVEAAQAVGVNPNQIYAWKKHFE------DQASGVALSDDERAELRKLRAENKRLRMEKEILKK 86
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRgggeaaDAGRLKELLTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  87 ASGLLRqgNEINFKFIHQARQEgYPVGLSCKTLGLSRSGYYAWDKRPAQLITEDTLMLYRTAKQLFKDSRESLGSRELMK 166
Cdd:NF033516   81 ARKLLR--PAVKYALIDALRGE-YSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 167 KLNQHGFAIGRYKTRSIMQRLNLVVRQRVAYKV-TTQRDKRHLAAPNLVSMDFNPERPNQVWAGDITYLKTAQGWMYLSV 245
Cdd:NF033516  158 LLRREGIRVNHKRVYRLMRELGLLARRRRKRRPyTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 246 VMDLYSRRIVGWSISKRMTTDLVLKSLQQAYWLRKHPKGVIFHSDRGSQYTSKKLRKALVRMGIKQSMGDTGACWDNAVV 325
Cdd:NF033516  238 VLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVA 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1580982069 326 ERFFGSLKHDWILKVHHATYEEMVADVTAYMKYYNVKRLHTANGDVSPVEYE 377
Cdd:NF033516  318 ESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
63-382 2.28e-97

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 292.44  E-value: 2.28e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  63 ERAELRKLRAENKRLRMEKEILKKASGLLRQGNEINFKFIHQARQEgypvglscktlgLSRSGYYAWDKRPAQLITEDTL 142
Cdd:COG2801     4 EEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRR------------RARSRRRRRLRRPRSYRADEDA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 143 MLYRTAKQLFKDSReSLGSRELMKKLNQHGFAIGRYKTRSIMQRLNLVVRQRVAYKVTTQRDKRHLAAPNLVsmdFNPER 222
Cdd:COG2801    72 ELLERIKEIFAESP-RYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYTTYSGHGGPIAPNLL---FTATA 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 223 PNQVWAGDITYLKTAQGWMYLSVVMDLYSRRIVGWSISKRMTTDLVLKSLQQAYWLRKHPKGVIFHSDRGSQYTSKKLRK 302
Cdd:COG2801   148 PNQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYTSKAYQE 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 303 ALVRMGIKQSMGDTGACWDNAVVERFFGSLKHDWILKVHHATYEEMVADVTAYMKYYNVKRLHTANGDVSPVEYENYQLK 382
Cdd:COG2801   228 LLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIEFYNHERPHSSLGYLTPAEYEKQLAA 307
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 119-384 1.05e-78

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 243.62  E-value: 1.05e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 119 LGLSRSGYYAW-------DKRPAQLITEDtlMLYRTAKQLFKDSRESLGSRELMKKLNQHGFAIGRYKTRSIMQRLNLVV 191
Cdd:PHA02517    1 LGIAPSTYYRCqqqrhhpDKRRARAQHDD--WLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 192 RQRVAYKVTTQRDKrHLAAPNLVSMDFNPERPNQVWAGDITYLKTAQGWMYLSVVMDLYSRRIVGWSISKRMTTDLVLKS 271
Cdd:PHA02517   79 VLRGKKVRTTISRK-AVAAPDRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 272 LQQAYWLRKHPKGVIFHSDRGSQYTSKKLRKALVRMGIKQSMGDTGACWDNAVVERFFGSLKHDWILKVHHATYEEMVAD 351
Cdd:PHA02517  158 LEQALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELA 237

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1580982069 352 VTAYMKYYNVKRLHTANGDVSPVEYENYQLKVS 384
Cdd:PHA02517  238 TLEWVAWYNNRRLHERLGYTPPAEAEKAYYASI 270
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 223-319 1.75e-30

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 112.41  E-value: 1.75e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 223 PNQVWAGDITYLK--TAQGWMYLSVVMDLYSRRIVGWSISKRMTTDLVLKSLQQAYWLRkHPKGVIFHSDRGSQYTSKKL 300
Cdd:pfam00665   1 PNQLWQGDFTYIRipGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFR-GGVPLIIHSDNGSEYTSKAF 79

                          90
                  ....*....|....*....
gi 1580982069 301 RKALVRMGIKQSMGDTGAC 319
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
1-91 5.77e-26

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 100.00  E-value: 5.77e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069   1 MNQKRKynSYTKEFKQEAVALVTEQGYSVVEAAQAVGVNPNQIYAWKKHFEDQASGVA----LSDDERAELRKLRAENKR 76
Cdd:COG2963     1 MSKKRR--RYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLGGFpgdgRTTPEQAEIRRLRKELRR 78

                          90
                  ....*....|....*
gi 1580982069  77 LRMEKEILKKASGLL 91
Cdd:COG2963    79 LEMENDILKKAAALL 93
transpos_IS481 NF033577
IS481 family transposase; null
 99-375 7.27e-20

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 88.42  E-value: 7.27e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  99 FKFIHQARQEGYPVGLSCKTLGLSRSGYYAW------------------DKRPAQLITEDT----LMLYRTAKqlfkdsr 156
Cdd:NF033577    3 LELVRLVLEDGWSVREAARRFGISRKTVYKWlkryraggeeglidrsrrPHRSPRRTSPETeariLALRRELR------- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 157 esLGSRELMKKLNQHGFAIGRYKTRSIMQRLNLVVRQRVayKVTTQRDKRhlaapnlvsmdFNPERPNQVWAGDITYLKT 236
Cdd:NF033577   76 --LGPRRIAYELERQGPGVSRSTVHRILRRHGLSRLRAL--DRKTGKVKR-----------YERAHPGELWHIDIKKLGR 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069 237 AQ--GWMYLSVVMDLYSRRIVGwSISKRMTTDLVLKSLQQAYwlRKHPKGV--IFhSDRGSQYTSKK--LRKALVRMGIK 310
Cdd:NF033577  141 IPdvGRLYLHTAIDDHSRFAYA-ELYPDETAETAADFLRRAF--AEHGIPIrrVL-TDNGSEFRSRAhgFELALAELGIE 216

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1580982069 311 QSMGDTGACWDNAVVERFFGSLKHDWILKVHHATYEEMVADVTAYMKYYNVKRLHTANGDVSPVE 375
Cdd:NF033577  217 HRRTRPYHPQTNGKVERFHRTLKDEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPAE 281
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 1-80 5.95e-15

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 69.30  E-value: 5.95e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069   1 MNQKRKYnsyTKEFKQEAVALVTEQGYSVVEAAQAVGVNPNQIYAWKKhfedQASGVALSDDERAELRKLRAENKRLRME 80
Cdd:pfam01527   1 MKKRRRF---SEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRR----QYEGGMGASPARPRLTALEEENRRLKRE 73
rve_3 pfam13683
Integrase core domain;
307-373 1.55e-09

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 53.76  E-value: 1.55e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1580982069 307 MGIKQSMGDTGACWDNAVVERFFGSLKHDWILKVHHATYEEMVADVTAYMKYYNVKRLHTANGDVSP 373
Cdd:pfam13683   1 LGIEISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWREDYNTERPHSSLGYRTP 67
rve_2 pfam13333
Integrase core domain;
326-381 1.95e-06

Integrase core domain;


Pssm-ID: 372570 [Multi-domain]  Cd Length: 52  Bit Score: 44.56  E-value: 1.95e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1580982069 326 ERFFGSLKHDWILKVHHATYEEMVADVTAYMKYYNVKRLHtangDVSPVEYENYQL 381
Cdd:pfam13333   1 ESFFGSLKTEMVYGEHFKTLEELELAIFDYIEWYNNKRLK----GLSPVQYRNQSL 52
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
 15-73 6.06e-04

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 41.38  E-value: 6.06e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1580982069  15 KQEAVALVtEQGYSVVEAAQAVGVNPNQIYAWKKHFEDQ-ASGVA----------LSDDERAELRKLRAE 73
Cdd:COG3415    28 RLRAVLLL-AEGLSVREIAERLGVSRSTVYRWLKRYREGgLAGLKdrprggrpskLSDEQRERLLELLRE 96
HTH_28 pfam13518
Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is ...
 14-51 4.30e-03

Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.


Pssm-ID: 463908 [Multi-domain]  Cd Length: 52  Bit Score: 34.88  E-value: 4.30e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1580982069  14 FKQEAVALVTEqGYSVVEAAQAVGVNPNQIYAWKKHFE 51
Cdd:pfam13518   1 ERLKIVLLALE-GESIKEAARLFGISRSTVYRWIRRYR 37
Terminase_5 pfam06056
Putative ATPase subunit of terminase (gpP-like); This family of proteins are annotated as ...
 25-64 6.96e-03

Putative ATPase subunit of terminase (gpP-like); This family of proteins are annotated as ATPase subunits of phage terminase after. Terminases are viral proteins that are involved in packaging viral DNA into the capsid.


Pssm-ID: 428745 [Multi-domain]  Cd Length: 58  Bit Score: 34.67  E-value: 6.96e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1580982069  25 QGYSVVEAAQAVGVNPNQIYAWKKHFE----DQASGVALSDDER 64
Cdd:pfam06056  12 QGYRPAEIAEMLGLKEATVYSWKQRDEwdglDPLSRIESSIAAR 55
transpos_IS630 NF033545
IS630 family transposase;
15-73 8.17e-03

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 37.62  E-value: 8.17e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1580982069  15 KQEAVALVTEQGYSVVEAAQAVGVNPNQIYAWKKHFEDQasGVA-------------LSDDERAELRKLRAE 73
Cdd:NF033545    1 RRARILLLAAEGLSITEIAERLGVSRSTVYRWLKRFNEG--GLEglldkprpgrprkLLSEQQAELLALLLE 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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