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Conserved domains on  [gi|1583032753|ref|WP_130612612|]
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iron ABC transporter permease [Fluviispira sanaruensis]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 24-336 6.39e-70

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 220.33  E-value: 6.39e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  24 SIYHGSVKLSFSEVLNSSFAFSSNEYK---ILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGGTCFL 100
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGPDGDPTAdliVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 101 ALFIILSSTQFFSdlsfqnfipFQSIFTFIGCFLSFFILIFFRKKIKSVNdeyiyPV----IGIIINSFFSSISLMIITL 176
Cdd:COG0609    81 VLAIVLGGGLSAL---------GLPLAAFLGALLAALLVYLLARRGGGLS-----PLrlvlAGVAVSALFSALTSLLLLL 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 177 ARPEQLSEIHNAMIGTLQPITLIQLFIFYTMSIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSL 256
Cdd:COG0609   147 ADPEQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGA 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 257 VVSTAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILIRKK 336
Cdd:COG0609   227 AVAVAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 24-336 6.39e-70

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 220.33  E-value: 6.39e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  24 SIYHGSVKLSFSEVLNSSFAFSSNEYK---ILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGGTCFL 100
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGPDGDPTAdliVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 101 ALFIILSSTQFFSdlsfqnfipFQSIFTFIGCFLSFFILIFFRKKIKSVNdeyiyPV----IGIIINSFFSSISLMIITL 176
Cdd:COG0609    81 VLAIVLGGGLSAL---------GLPLAAFLGALLAALLVYLLARRGGGLS-----PLrlvlAGVAVSALFSALTSLLLLL 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 177 ARPEQLSEIHNAMIGTLQPITLIQLFIFYTMSIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSL 256
Cdd:COG0609   147 ADPEQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGA 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 257 VVSTAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILIRKK 336
Cdd:COG0609   227 AVAVAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 16-334 1.07e-57

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 188.89  E-value: 1.07e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  16 IFFLSAFLSIYHGSVKLSFSEVLNSSFAFSSNEYK--ILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGIS 93
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGDDSLAAliVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  94 SGGTCFLALFIIlsstqFFSDLSFQNFIPFQSIFTFIGCFLSFFILIFFRKKiksvnDEYIYPVIGIIINSFFSSISLMI 173
Cdd:pfam01032  81 SGAALGAVLAIL-----LGGSLSLFALPLAAFIGALLAALLVYFLSRGRGGA-----SPLRLILAGIAVSALLSALTSLL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 174 ITLARPEQLSEIHNAMIGTLQPITLIQLFIFYTMSIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFL 253
Cdd:pfam01032 151 LLLLNPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLL 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 254 VSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILI 333
Cdd:pfam01032 231 TAASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLL 310


                  .
gi 1583032753 334 R 334
Cdd:pfam01032 311 R 311
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 51-336 2.37e-38

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 138.83  E-value: 2.37e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  51 ILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGGTCFLALFIILSSTQFFsdlsfqnfipfqSIFTFI 130
Cdd:TIGR03869  49 VWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVAVLL------------PVAAFA 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 131 GCFLSFFILIFFRKKIKSVNDEYIYpVIGIIINSFFSSI-SLMIITLARPEQLSEIHNAMIGTLQPITLIQLFIFYTMSI 209
Cdd:TIGR03869 117 GALLALAATLGLARTLGTLTPTRTI-LAGLAVSQLCAAVtSFVIFWSATGDSYREILSWLMGSLAGATWGSVAIAGGALL 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 210 MPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECIL 289
Cdd:TIGR03869 196 VVGLVLLASGRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRHRLLLPV 275

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1583032753 290 SMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILIRKK 336
Cdd:TIGR03869 276 SALAGAVFLVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSR 322
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
51-334 4.55e-38

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 143.44  E-value: 4.55e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  51 ILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGGTCFLALFIILSSTQFFsdlsfqnfiPFQSIFTFI 130
Cdd:PRK10577  393 LLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGF---------GWLLAAALL 463

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 131 GCFLSFFILIFFRKKiKSVNDEYIYpVIGIIINSFFSSISLMIITLARPeQLSEIHNAMIGTLQPITL--IQLFIFYTMS 208
Cdd:PRK10577  464 GALAALALILLLARR-GGFAPERLL-LTGIALSALFTALIQLLLASGDP-RAAQLLTWLSGSTYGVTWaqALPLLIVAVL 540

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 209 IMPIFFLLRNtnYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECI 288
Cdd:PRK10577  541 LLALALLLRR--WLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLV 618

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1583032753 289 LSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILIR 334
Cdd:PRK10577  619 LAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRR 664
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 59-332 1.54e-33

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 124.21  E-value: 1.54e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  59 LMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGgtcflALFIILSSTQFFSDLSFQNFIPFQSIFTFIGCFLSFFI 138
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHG-----ALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 139 LIFFRKKIKSVndeyiyPVIGIIINSFFSSIsLMIITLARPEQLSEIHNAMIGTLQPITLIQLFIFYTMSIMPIFFLLRN 218
Cdd:cd06550    76 ASRGGLSPSKL------ILIGIVLSAFFSAG-VILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLL 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 219 TNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVL 298
Cdd:cd06550   149 SRKLNLLTFDEDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILL 228

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1583032753 299 INADTLSRSLFsPAQLPLGIFTAILGAPVLAFIL 332
Cdd:cd06550   229 LLGDLLSRTLL-PSELPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 24-336 6.39e-70

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 220.33  E-value: 6.39e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  24 SIYHGSVKLSFSEVLNSSFAFSSNEYK---ILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGGTCFL 100
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGPDGDPTAdliVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 101 ALFIILSSTQFFSdlsfqnfipFQSIFTFIGCFLSFFILIFFRKKIKSVNdeyiyPV----IGIIINSFFSSISLMIITL 176
Cdd:COG0609    81 VLAIVLGGGLSAL---------GLPLAAFLGALLAALLVYLLARRGGGLS-----PLrlvlAGVAVSALFSALTSLLLLL 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 177 ARPEQLSEIHNAMIGTLQPITLIQLFIFYTMSIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSL 256
Cdd:COG0609   147 ADPEQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGA 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 257 VVSTAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILIRKK 336
Cdd:COG0609   227 AVAVAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 16-334 1.07e-57

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 188.89  E-value: 1.07e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  16 IFFLSAFLSIYHGSVKLSFSEVLNSSFAFSSNEYK--ILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGIS 93
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGDDSLAAliVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  94 SGGTCFLALFIIlsstqFFSDLSFQNFIPFQSIFTFIGCFLSFFILIFFRKKiksvnDEYIYPVIGIIINSFFSSISLMI 173
Cdd:pfam01032  81 SGAALGAVLAIL-----LGGSLSLFALPLAAFIGALLAALLVYFLSRGRGGA-----SPLRLILAGIAVSALLSALTSLL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 174 ITLARPEQLSEIHNAMIGTLQPITLIQLFIFYTMSIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFL 253
Cdd:pfam01032 151 LLLLNPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLL 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 254 VSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILI 333
Cdd:pfam01032 231 TAASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLL 310


                  .
gi 1583032753 334 R 334
Cdd:pfam01032 311 R 311
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 14-336 3.93e-43

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 151.54  E-value: 3.93e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  14 TFIFFLSAFLSIYHGSVKLSFSEVLNSSfafssNEYKILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGIS 93
Cdd:COG4139    19 LLLLLLLFVLSLCAGEVWIPPTQWLSEA-----WQLFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGIS 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  94 SGGTCFLALFIILSStQFFSDLSFqnfipfqSIFTFIGCFLSFFILIFFRKKIKSVNDEYIypvIGIIINSFFSSISLMI 173
Cdd:COG4139    94 NGAGVGLVLVVLLGG-GLLPPWLL-------SLAAIAGALLVTLLLLAFARRRLSNARLLL---IGVALGIICSAIMTWA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 174 ITLARPEQLSEIHNAMIGTLQPITLIQLFIFYTMsIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFL 253
Cdd:COG4139   163 VYFSSSLDLRQLMYWMMGSFGGVDWRQLWLLLAL-LPVLLWLCLQGKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLL 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 254 VSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILI 333
Cdd:COG4139   242 VGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALLLLADIIARLALSSAELPIGVVTATLGAPVFIWLLL 321


                  ...
gi 1583032753 334 RKK 336
Cdd:COG4139   322 RRR 324
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 51-336 2.37e-38

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 138.83  E-value: 2.37e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  51 ILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGGTCFLALFIILSSTQFFsdlsfqnfipfqSIFTFI 130
Cdd:TIGR03869  49 VWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVAVLL------------PVAAFA 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 131 GCFLSFFILIFFRKKIKSVNDEYIYpVIGIIINSFFSSI-SLMIITLARPEQLSEIHNAMIGTLQPITLIQLFIFYTMSI 209
Cdd:TIGR03869 117 GALLALAATLGLARTLGTLTPTRTI-LAGLAVSQLCAAVtSFVIFWSATGDSYREILSWLMGSLAGATWGSVAIAGGALL 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 210 MPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECIL 289
Cdd:TIGR03869 196 VVGLVLLASGRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRHRLLLPV 275

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1583032753 290 SMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILIRKK 336
Cdd:TIGR03869 276 SALAGAVFLVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSR 322
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
51-334 4.55e-38

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 143.44  E-value: 4.55e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  51 ILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGGTCFLALFIILSSTQFFsdlsfqnfiPFQSIFTFI 130
Cdd:PRK10577  393 LLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGF---------GWLLAAALL 463

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 131 GCFLSFFILIFFRKKiKSVNDEYIYpVIGIIINSFFSSISLMIITLARPeQLSEIHNAMIGTLQPITL--IQLFIFYTMS 208
Cdd:PRK10577  464 GALAALALILLLARR-GGFAPERLL-LTGIALSALFTALIQLLLASGDP-RAAQLLTWLSGSTYGVTWaqALPLLIVAVL 540

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 209 IMPIFFLLRNtnYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECI 288
Cdd:PRK10577  541 LLALALLLRR--WLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLV 618

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1583032753 289 LSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILIR 334
Cdd:PRK10577  619 LAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRR 664
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
14-336 5.20e-35

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 134.58  E-value: 5.20e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  14 TFIFFLSAFLSIYHGSVKLSFSEVLNSSFAFSSNEYKILELRFNSL---MQAALVGAILALSGCVLQRVLRNPLADPFIL 90
Cdd:PRK10577   18 ALLLLLALALTLTQLSAALPLSQWLQALWGPDADDLEQLLLHYSRLprlAIALLVGAALGLAGALLQQVLRNPLASPTTL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  91 GISSGGtcFLALFIilsSTQFFSDLSFQnfipFQSIFTFIG--CFLSFFILIFFRKKIKSVndeyiyPVI--GIIINSFF 166
Cdd:PRK10577   98 GVAAGA--QLALVL---ATLFAPALLAL----ASQLAAFAGglLAAALVFALAGGKRLSPL------RLVlaGMVVSLYL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 167 SSISLMIItLARPEQLSeihNAMI---GTLQPI---TLIQLFIFYTMSIMPIFFLLRNtnyFDLMLFGDDFSKSMGINPV 240
Cdd:PRK10577  163 GALTTLLL-LFNEQYLQ---GLFLwgaGSLAQNdwsGVQRLLPRLLVGLLLLLLLARP---LTLLGLGDDVARSLGLAVS 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 241 KLRKTSIVMICFLVSLVVSTAGSIGFIGLIIPHMIRRL--HRFSARFecILSMILGAIVLINADTLSRSL--FSPAQLPL 316
Cdd:PRK10577  236 LTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLgaRRLRARL--PLSPLIGALLLLLTDQLVRLLagVGGELLPT 313

                         330       340
                  ....*....|....*....|
gi 1583032753 317 GIFTAILGAPVLAFILIRKK 336
Cdd:PRK10577  314 GAVTALIGAPLLLWLLPRLR 333
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
23-336 3.80e-34

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 127.47  E-value: 3.80e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  23 LSIYHGSVKLSFSEVLNSSFAFSSNEYKILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGgtcflAL 102
Cdd:PRK09777   19 LSLRMGVIPLPWRALLTDWQAGDEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNHA-----AS 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 103 FIILSSTQFFSDLSFQnFIPfqsIFTFIGCFLSFFILiffrKKIKSVNDEYIYPVIGIIINSFFSSISLMIItLARPEql 182
Cdd:PRK09777   94 LASVGALLLFPSLPVM-WLP---LLAFIGGMAGLILL----KMLAGTHQPMKLALTGVALSALWASLTDYLM-LSRPQ-- 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 183 sEIHNAMI---GTLQPITLIQLFIFYTMSIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSLVVS 259
Cdd:PRK09777  163 -DINNALLwltGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVA 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1583032753 260 TAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILIRKK 336
Cdd:PRK09777  242 ACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLLVRMR 318
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 59-332 1.54e-33

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 124.21  E-value: 1.54e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  59 LMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGgtcflALFIILSSTQFFSDLSFQNFIPFQSIFTFIGCFLSFFI 138
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHG-----ALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 139 LIFFRKKIKSVndeyiyPVIGIIINSFFSSIsLMIITLARPEQLSEIHNAMIGTLQPITLIQLFIFYTMSIMPIFFLLRN 218
Cdd:cd06550    76 ASRGGLSPSKL------ILIGIVLSAFFSAG-VILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLL 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 219 TNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVL 298
Cdd:cd06550   149 SRKLNLLTFDEDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILL 228

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1583032753 299 INADTLSRSLFsPAQLPLGIFTAILGAPVLAFIL 332
Cdd:cd06550   229 LLGDLLSRTLL-PSELPVGPVTALLGAPYFLYLL 261
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
15-336 5.61e-31

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 119.03  E-value: 5.61e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  15 FIFFLSAFLsiyHGSVKLSFSEVLNSSFAFSSN---EYKILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILG 91
Cdd:PRK11228   11 GLFWLSLFC---YSAIPISAADALNALLPGHTPtlpEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  92 ISSGGTCFLALFIILSSTqFFSDLSFqnfipfqSIFTFIGCFLSFFILIFFRKKIKSVNDEYIYPVIGIIINSFFSSISL 171
Cdd:PRK11228   88 INSGAALAMALTSALSPT-PFAGYSL-------AFIAACGGGLSWLLVMTAGGGWRHTHDRNRLILAGIALSALCMALTR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 172 MIITLARpEQLSEIHNAMIGTLQPITLIQLFIFYTMSIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMIC 251
Cdd:PRK11228  160 ITLLLAE-DHAYGIFYWLAGGVSHARWQEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVL 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 252 FLVSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFi 331
Cdd:PRK11228  239 LLVGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVW- 317


                  ....*
gi 1583032753 332 LIRKK 336
Cdd:PRK11228  318 LARRR 322
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 51-336 7.88e-31

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 118.90  E-value: 7.88e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  51 ILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGGTcfLALFIILsstqffsdLSFQNFIPFQ--SIFT 128
Cdd:PRK03784   54 VWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAG--VALVAAV--------LLGQGLLPPWalSLCA 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 129 FIG--CFLSFFILIFFRKKIKSVNDEYIYPVIGIIINS-----FFSSISLmiitlarpeQLSEIHNAMIGTLQPITLIQL 201
Cdd:PRK03784  124 IAGalLITLILLRFARRHRLSTSRLLLAGVALGIICSAlmtwaVYFSTSL---------DLRQLMYWMMGGFGGVDWRQS 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 202 FIFYTMsIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSLVVSTAGSIGFIGLIIPHMIRRLHRF 281
Cdd:PRK03784  195 WLMLAL-LPVLIWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLT 273

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1583032753 282 SARFECILSMILGAIVLINADTLSRSLFSPAQLPLGIFTAILGAPVLAFILIRKK 336
Cdd:PRK03784  274 DHRVLLPGCALAGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSH 328
btuC PRK09535
cobalamin ABC transporter permease BtuC;
40-337 4.99e-25

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 103.68  E-value: 4.99e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  40 SSFAF---SSNEYKILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGISSGGTCFLALFIILSSTqffsdls 116
Cdd:PRK09535   77 SPFSFavpETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLA------- 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 117 fqnfIPFQ-SIFTFIGCFLSFFILIFfrkkIKSVNDEyiYPV-----IGIIINSFFSS-ISLMIitLARPEQLSEIHNAM 189
Cdd:PRK09535  150 ----VPFGlQAAAFAGALVAAFGVYA----IATENGR--TPVatlllAGVAVQTFLGAvISYLL--LHSGESLRRAVYWL 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 190 IGTLQPITLIQLFIFYTMSIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVKLRKTSIVMICFLVSLVVSTAGSIGFIGL 269
Cdd:PRK09535  218 MGHLHGSTWSDVEVALPVVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGL 297

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1583032753 270 IIPHMIRRL----HRfsarfecIL---SMILGAIVLINADTLSRSlfSPAQLPLGIFTAILGAPVLAFILIRKKV 337
Cdd:PRK09535  298 IVPHVMRLLvgpdHR-------ILlptSALAGASFLVATDTVARS--GPAEVPVGIVTAALGAPFFLYLLRTREV 363
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
16-336 7.90e-18

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 82.83  E-value: 7.90e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  16 IFFLSAFLSIYHGSVKLSFSEVLNSSFA--FSSNEYKILELRFNSLMQAALVGAILALSGCVLQRVLRNPLADPFILGIS 93
Cdd:PRK10441   19 LLIIATALSLLIGAKSLPASVVLEALSGtcQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVN 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  94 SGgtcflALFIILSSTQFFSDLSfqnfIPFQSIFTFIGCFLSFFILIFFRKKIKSVNDEYIYPVIGIIINSFFSSISLMI 173
Cdd:PRK10441   99 AG-----ASFAIVLGAALFGYSS----AQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLTSGI 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 174 iTLARPEQLSEIH-----NAMIGTLQPITLIQLFIFytMSIMPIFFLLRNTNYFDLmlfGDDFSKSMGINPVKLRKTSIV 248
Cdd:PRK10441  170 -ALLNPDVYDQLRfwqagSLDIRNLHTLKVVLIPVL--IAGATALLLSRALNSLSL---GSDTATALGSRVARTQLIGLL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 249 MICFLVSLVVSTAGSIGFIGLIIPHMIRRLHRFSARFECILSMILGAIVLINADTLSRsLFSPAQLPLGIFTAILGAPVL 328
Cdd:PRK10441  244 AITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGR-LLVPGELRVSVVSAFIGAPVL 322


                  ....*...
gi 1583032753 329 AFILIRKK 336
Cdd:PRK10441  323 IFLVRRKT 330
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
6-334 3.66e-16

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 78.21  E-value: 3.66e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753   6 SLKVCSIYTFIFFLSAFLSIYHGSVKLSFSEVLNSSF--AFSSNEYKILELRFNSLMQAALVGAILALSGCVLQRVLRNP 83
Cdd:PRK10440    8 LLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMgdAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753  84 LADPFILGISSGGTCFLALFIILSSTQFFSdlsfqnfIPFQSIFTFIgCFLSFFILIFFRKKIksvnDEYIYPVIGIIIN 163
Cdd:PRK10440   88 LGSPDVMGFNTGAWSGVLVAMVLFGQDLTA-------IALAAMAGGI-VTSLLVWLLAWRNGI----DTFRLIIIGIGVR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 164 SFFSSISLMIITLARPEQL--SEIHNAmiGTLQPITLIQLFIFYTMSIMPIFFLLRNTNYFDLMLFGDDFSKSMGINPVK 241
Cdd:PRK10440  156 AMLVAFNTWLLLKASLETAltAGLWNA--GSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVER 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583032753 242 LRKTSIVMICFLVSLVVSTAGSIGFIGLIIPHMIRRLHRfSARFECILSMILGAIVLINADTLSRSLFSPAQLPLGIFTA 321
Cdd:PRK10440  234 SRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLSG-TARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTV 312

                         330
                  ....*....|...
gi 1583032753 322 ILGAPVLAFILIR 334
Cdd:PRK10440  313 SLGGIYLIVLLIQ 325
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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