|
Name |
Accession |
Description |
Interval |
E-value |
| his_kin_PieS |
NF041210 |
two component system sensor histidine kinase PieS; |
1-475 |
7.07e-140 |
|
two component system sensor histidine kinase PieS;
Pssm-ID: 469114 [Multi-domain] Cd Length: 474 Bit Score: 410.33 E-value: 7.07e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 1 MRYLYQQLLAFCGMVALIL--LIVGVSFTQLTKQTIEENNYQQLFGYAESVEKTTQTYADtlpqfsQDQAFQnALLLTEQ 78
Cdd:NF041210 1 MKFKYQYQLFLTQFIILLIacLMIGLLISHFLKDYFFESQVNDLTKYGVTISRDIKYMSD------EDQTVP-VLNTYQR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 79 VLTEQNVNFIFIDKNERVIYPTNTALL--NFTLTTDQWKNLRSGrqeKFTSNKNILGQAQATSYALVPFNLNHEFYGALV 156
Cdd:NF041210 74 ILDVKNIHYTILNNNNQIIYPNNNRPLppDFKISDADMKKLEKG---ETVSIKVDNRFNQEMSVVYVPILNGDEFLGSII 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 157 VSQPARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFN 236
Cdd:NF041210 151 LNSPISGTEKVIGTINQYMFYTILLSITIALILSAILSKLQVNRINKLRKATKRVIRGNYETRLKENNFDEIGALAHDFN 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 237 KMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYE 316
Cdd:NF041210 231 KMTETLAESKEEIERQEKRRRQFIADVSHEMRTPLTTISGLTEGLVNDIIPKSETDRCIALIDTEAKRLTKLVNENLDYE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 317 KIRTNQISMVIKKFNGTETLRNIVAQLEAKAEAAEDTLILKADDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIMVTLE 396
Cdd:NF041210 311 RIRSNKIQLYKTRFGVHAFLDLIKEQLEPLASEKGNQIIVDAPLDLEVYADYDRLTQIVINIVKNSIQFTENGTITLTGR 390
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1583047749 397 KGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:NF041210 391 QDYKETILTITDTGIGMDTGELEQIWERFYKADMSRTSTAFGESGIGLSIVKQLVEYHDGSIEVESEPNKGTTFTIRLP 469
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
161-475 |
8.44e-73 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 235.22 E-value: 8.44e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 161 ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTN 240
Cdd:COG5002 70 LLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLA 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 241 SLKESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAI-PENQRENAIKLMKNETERLIRLVNENLDYEKIR 319
Cdd:COG5002 150 AVERDITELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAAdDPEERREYLEIILEEAERLSRLVNDLLDLSRLE 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 320 TNQISMVIKKFNGTETLRNIVAQLEAKAEAAEDTLILKA-DDDIDVYADYDRFVQIMVNIIQNAIQFT-ENGQIMVTLEK 397
Cdd:COG5002 230 SGELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLpEDPLLVLGDPDRLEQVLTNLLDNAIKYTpEGGTITVSLRE 309
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1583047749 398 GYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRkNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:COG5002 310 EDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSR-SRETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLP 386
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
147-475 |
1.78e-66 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 216.70 E-value: 1.78e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 147 LNHEFYGALVVSQPARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKD 226
Cdd:COG0642 1 LLLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 227 EFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEyNAIPENQREnAIKLMKNETERLI 306
Cdd:COG0642 81 LLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLL-EELDEEQRE-YLETILRSADRLL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 307 RLVNENLDYEKIRTNQISMVIKKFNGTETLRNIVAQLEAKAEAAEDTLILKADDDID-VYADYDRFVQIMVNIIQNAIQF 385
Cdd:COG0642 159 RLINDLLDLSRLEAGKLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPtVRGDPDRLRQVLLNLLSNAIKY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 386 T-ENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKntkYGESGLGLPIVQQLVRLHKGKLEVESEL 464
Cdd:COG0642 239 TpEGGTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSRR---GGGTGLGLAIVKRIVELHGGTIEVESEP 315
|
330
....*....|.
gi 1583047749 465 GKGTKFTVRLP 475
Cdd:COG0642 316 GKGTTFTVTLP 326
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
242-475 |
3.19e-64 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 207.84 E-value: 3.19e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 242 LKESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGL-EYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRT 320
Cdd:COG2205 2 LEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLlDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLES 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 321 NQISMVIKKFNGTETLRNIVAQLEAKAEAAEDTLILK-ADDDIDVYADYDRFVQIMVNIIQNAIQFT-ENGQIMVTLEKG 398
Cdd:COG2205 82 GKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDlPPELPLVYADPELLEQVLANLLDNAIKYSpPGGTITISARRE 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1583047749 399 YLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKntkYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:COG2205 162 GDGVRISVSDNGPGIPEEELERIFERFYRGDNSRG---EGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLP 235
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
180-475 |
2.38e-45 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 163.59 E-value: 2.38e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 180 IFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENR---- 255
Cdd:COG5000 16 LLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQREELEERRRYleti 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 256 -----------------------------------------------------------------------RRQFMADAS 264
Cdd:COG5000 96 lenlpagvivldadgritlanpaaerllgipleeligkpleellpeldlaellrealergwqeeieltrdgRRTLLVRAS 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 265 ----------------------------------HEMRTPLTTINGLLEGLE--YNAIPENQREN---AIKLMKNETERL 305
Cdd:COG5000 176 plrddgyvivfdditellraerlaawgelarriaHEIKNPLTPIQLSAERLRrkLADKLEEDREDlerALDTIIRQVDRL 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 306 IRLVNENLDYEKIRTNQISMVikkfNGTETLRNIVAQLEAKAEAAEDTLILK-ADDDIDVYADYDRFVQIMVNIIQNAIQ 384
Cdd:COG5000 256 KRIVDEFLDFARLPEPQLEPV----DLNELLREVLALYEPALKEKDIRLELDlDPDLPEVLADRDQLEQVLINLLKNAIE 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 385 FTE-NGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKvdpsrknTKYGESGLGLPIVQQLVRLHKGKLEVESE 463
Cdd:COG5000 332 AIEeGGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFFT-------TKPKGTGLGLAIVKKIVEEHGGTIELESR 404
|
410
....*....|..
gi 1583047749 464 LGKGTKFTVRLP 475
Cdd:COG5000 405 PGGGTTFTIRLP 416
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
248-474 |
4.38e-45 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 160.45 E-value: 4.38e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 248 EIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQREN-AIKLMKNETERLIRLVNENLDYEKIRTNQISMV 326
Cdd:TIGR02966 106 RLRRLEQMRRDFVANVSHELRTPLTVLRGYLETLADGPDEDPEEWNrALEIMLEQSQRMQSLVEDLLTLSRLESAASPLE 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 327 IKKFNGTETLRNIVAQLEAKAEAAEDTLILKADDDIDVYADYDRFVQIMVNIIQNAIQFT-ENGQIMVTLEKGYLETIIT 405
Cdd:TIGR02966 186 DEPVDMPALLDHLRDEAEALSQGKNHQITFEIDGGVDVLGDEDELRSAFSNLVSNAIKYTpEGGTITVRWRRDGGGAEFS 265
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1583047749 406 IEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKyGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRL 474
Cdd:TIGR02966 266 VTDTGIGIAPEHLPRLTERFYRVDKSRSRDT-GGTGLGLAIVKHVLSRHHARLEIESELGKGSTFSFIF 333
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
144-475 |
1.48e-42 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 156.91 E-value: 1.48e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 144 PFNLNHEFYGALVVSQPARNIDNSvrpiTLNLFKG--------FIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGN 215
Cdd:NF012163 131 PILVNGQEVGALGASPVERLTRNT----DINFDSQqkraswliVALALLLAALAAFLLARGLLAPVKRLVEATHRLAAGD 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 216 FDVQLPVHDKDEFDELADDFNKMTNSLkesqaeiEEQENRRRQFMADASHEMRTPLTTINGLLEGLEyNAIPENQRENAI 295
Cdd:NF012163 207 YTTRVTPTSNDELGKLAQDFNQLASTL-------EKNEQMRRDFMADISHELRTPLAVLRAELEAIQ-DGIRKFTPESLD 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 296 KLMKnETERLIRLVNENLDYEKIRTNQISMVIKKFNGTETLRNIVAQLEAKAEAAEDTLILKADDDIDVYADYDRFVQIM 375
Cdd:NF012163 279 SLQA-EVGTLTKLVDDLHDLSMSDEGALAYQKASVDLVPLLEVEGGAFRERFASAGLELEVSLPDSSLVFGDRDRLMQLF 357
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 376 VNIIQNAIQFTEN-GQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRkNTKYGESGLGLPIVQQLVRLH 454
Cdd:NF012163 358 NNLLENSLRYTDSgGSLHISASQRPKEVTLTVADSAPGVSDEQLARLFERFYRVEVSR-NRASGGSGLGLAISLNIVQAH 436
|
330 340
....*....|....*....|..
gi 1583047749 455 KGKLEVE-SELGkGTKFTVRLP 475
Cdd:NF012163 437 GGTLHAAhSPLG-GLRIVVTLP 457
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
144-475 |
1.39e-39 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 149.01 E-value: 1.39e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 144 PFNLNHEFYGALVVSQPAR-------NIDNSVRpITLNLFKGFifSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNF 216
Cdd:PRK10549 131 PILVNGAEVGWVIASPVERltrntdiNFDKQQR-RTSWLIVAL--STLLAALATFLLARGLLAPVKRLVEGTHKLAAGDF 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 217 DVQLPVHDKDEFDELADDFNKMTNSLkesqaeiEEQENRRRQFMADASHEMRTPLTTINGLLEgleynAIPENQRE---N 293
Cdd:PRK10549 208 TTRVTPTSRDELGRLAQDFNQLASTL-------EKNEQMRRDFMADISHELRTPLAVLRGELE-----AIQDGVRKftpE 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 294 AIKLMKNETERLIRLVNE----------NLDYEKIRTNQISMV---IKKFNGTETLRNIvaqleakaeaaedTLILKADD 360
Cdd:PRK10549 276 SVASLQAEVGTLTKLVDDlhqlslsdegALAYRKTPVDLVPLLevaGGAFRERFASRGL-------------TLQLSLPD 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 361 DIDVYADYDRFVQIMVNIIQNAIQFT-ENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRkNTKYGE 439
Cdd:PRK10549 343 SATVFGDPDRLMQLFNNLLENSLRYTdSGGSLHISAEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSR-NRASGG 421
|
330 340 350
....*....|....*....|....*....|....*..
gi 1583047749 440 SGLGLPIVQQLVRLHKGKLEVE-SELGkGTKFTVRLP 475
Cdd:PRK10549 422 SGLGLAICLNIVEAHNGRIIAAhSPFG-GVSITVELP 457
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
143-475 |
1.60e-39 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 149.41 E-value: 1.60e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 143 VPFNLNHEFYgaLVVSqparnIDNSVRpiTLNLFKGFIFSSIVAVIASYAFAAFQVKR-----INRLRNATKEVTNGNFD 217
Cdd:NF040691 162 LPVAGNYELY--LLFP-----LEDEQS--TLALVRGTLLLGGLALVVLLGLIAWLVTRqvvapVRSAARTAERFAAGDLS 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 218 VQLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTINgLLEGLEYNAIPE--NQRENAI 295
Cdd:NF040691 233 ERMPVKGEDDLARLARSFNQMADSLQRQIRQLEELSRLQQRFVSDVSHELRTPLTTIR-MAADVIHDSRDDfdPATARSA 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 296 KLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTETLRNIVAQLEAKAEAAEDTLILKADD-DIDVYADYDRFVQI 374
Cdd:NF040691 312 ELLHTELDRFESLLSDLLEISRFDAGAAELDVEPVDLRPLVRRVVDALRQLAERAGVELRVDAPGtPVVAEVDPRRVERV 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 375 MVNIIQNAIQFTENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKyGESGLGLPIVQQLVRLH 454
Cdd:NF040691 392 LRNLVVNAIEHGEGKPVVVTVAQDDTAVAVTVRDHGVGLKPGEVALVFDRFWRADPARARTT-GGTGLGLAIALEDARLH 470
|
330 340
....*....|....*....|.
gi 1583047749 455 KGKLEVESELGKGTKFTVRLP 475
Cdd:NF040691 471 GGWLEAWGRPGQGSQFRLTLP 491
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
249-475 |
2.78e-38 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 147.21 E-value: 2.78e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 249 IEEQE---NRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQ-RENAIKLMKNETERLIRLVNENLDYEKIRTNQIS 324
Cdd:NF033092 362 VTEQEkieQERREFVANVSHELRTPLTTMRSYLEALADGAWKDPElAPRFLGVTQNETERMIRLVNDLLQLSRMDSKDYK 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 325 MVIKKFNGTETLRNIVAQLEAKAEAAEDTLILK-ADDDIDVYADYDRFVQIMVNIIQNAIQFT-ENGQIMVTLEKGYLET 402
Cdd:NF033092 442 LNKEWVNFNEFFNYIIDRFEMILKNKNITFKREfPKRDLWVEIDTDKITQVLDNIISNAIKYSpEGGTITFRLLETHNRI 521
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1583047749 403 IITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNtKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:NF033092 522 IISISDQGLGIPKKDLDKIFDRFYRVDKARSR-KMGGTGLGLAIAKEVVEAHGGRIWAESEEGKGTTIYFTLP 593
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
251-482 |
5.30e-37 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 139.60 E-value: 5.30e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 251 EQENRRRQFMADAS-------HEMRTPLTTINGLLEGLEYNAIPENQREnAIKLMKNETERLIRLVNENLDYEKIRTNQI 323
Cdd:COG3852 123 ERELRRAEKLAAVGelaaglaHEIRNPLTGIRGAAQLLERELPDDELRE-YTQLIIEEADRLNNLVDRLLSFSRPRPPER 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 324 SMVikkfngtetlrNIVAQLE-----AKAEAAED-TLILKADDDI-DVYADYDRFVQIMVNIIQNAIQ-FTENGQIMVTL 395
Cdd:COG3852 202 EPV-----------NLHEVLErvlelLRAEAPKNiRIVRDYDPSLpEVLGDPDQLIQVLLNLVRNAAEaMPEGGTITIRT 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 396 EKGYLETI----------ITIEDTGIGMSEQQMKSIWDRYYkvdpsrkNTKYGESGLGLPIVQQLVRLHKGKLEVESELG 465
Cdd:COG3852 271 RVERQVTLgglrprlyvrIEVIDNGPGIPEEILDRIFEPFF-------TTKEKGTGLGLAIVQKIVEQHGGTIEVESEPG 343
|
250
....*....|....*..
gi 1583047749 466 KGTKFTVRLPDVEIKEE 482
Cdd:COG3852 344 KGTTFRIYLPLEQAEEE 360
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
174-475 |
4.59e-35 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 135.98 E-value: 4.59e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 174 NLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDK-DEFDELADDFNKMTNSLkesqaeiEEQ 252
Cdd:TIGR01386 165 WLILIAVLLVLLTALLGWWITRLGLEPLRRLSAVAARISPESLDQRLDPSRApAELRELAQSFNAMLGRL-------EDA 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 253 ENRRRQFMADASHEMRTPLTTINGLLE--------GLEYNAIPENQREnaiklmknETERLIRLVNENLDYEKIRTNQIS 324
Cdd:TIGR01386 238 FQRLSQFSADLAHELRTPLTNLLGQTQvalsqprtGEEYREVLESNLE--------ELERLSRMVSDMLFLARADNGQLA 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 325 MVIKKFNGTETLRNIVAQLEAKAEaaEDTLILKADDDIDVYADYDRFVQIMVNIIQNAIQFT-ENGQIMVTLEKGYLETI 403
Cdd:TIGR01386 310 LERVRLDLAAELAKVAEYFEPLAE--ERGVRIRVEGEGLVRGDPQMFRRAISNLLSNALRHTpDGGTITVRIERRSDEVR 387
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1583047749 404 ITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGeSGLGLPIVQQLVRLHKGKLEVESELGKgTKFTVRLP 475
Cdd:TIGR01386 388 VSVSNPGPGIPPEHLSRLFDRFYRVDPARSNSGEG-TGLGLAIVRSIMEAHGGRASAESPDGK-TRFILRFP 457
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
366-475 |
1.19e-34 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 125.45 E-value: 1.19e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 366 ADYDRFVQIMVNIIQNAIQFT-ENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPsrKNTKYGESGLGL 444
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTpEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDK--RSRKIGGTGLGL 78
|
90 100 110
....*....|....*....|....*....|.
gi 1583047749 445 PIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:smart00387 79 SIVKKLVELHGGEISVESEPGGGTTFTITLP 109
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
253-475 |
5.47e-33 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 129.75 E-value: 5.47e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 253 ENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNG 332
Cdd:PRK11006 201 EGARRNFFANVSHELRTPLTVLQGYLEMMQDQPLEGALREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTIDLNEKVDV 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 333 TETLRniVAQLEAKAEAAED-TLILKADDDIDVYADYDRFVQIMVNIIQNAIQFTENG-QIMVTLEKGYLETIITIEDTG 410
Cdd:PRK11006 281 PMMLR--VLEREAQTLSQGKhTITFEVDNSLKVFGNEDQLRSAISNLVYNAVNHTPEGtHITVRWQRVPQGAEFSVEDNG 358
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1583047749 411 IGMSEQQMKSIWDRYYKVDPSR-KNTkyGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:PRK11006 359 PGIAPEHIPRLTERFYRVDKARsRQT--GGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLP 422
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
102-478 |
1.24e-32 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 129.91 E-value: 1.24e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 102 TALLNFTLTTDQWKNLRSGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQPARNIDNSVRPITLNLFKGFIF 181
Cdd:COG4251 128 LLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLL 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 182 SSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMA 261
Cdd:COG4251 208 ELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAELERSNEELEQFAY 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 262 DASHEMRTPLTTINGLLEGLE---YNAIPENQRENaIKLMKNETERLIRLVNENLDYekIRTNQISMVIKKFNGTETLRN 338
Cdd:COG4251 288 VASHDLREPLRKISGFSQLLEedyGDKLDEEGREY-LERIRDAAERMQALIDDLLAY--SRVGRQELEFEPVDLNELLEE 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 339 IVAQLEAKAEAAEDTLILkaDDDIDVYADYDRFVQIMVNIIQNAIQFT---ENGQIMVTLEKGYLETIITIEDTGIGMSE 415
Cdd:COG4251 365 VLEDLEPRIEERGAEIEV--GPLPTVRGDPTLLRQVFQNLISNAIKYSrpgEPPRIEIGAEREGGEWVFSVRDNGIGIDP 442
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1583047749 416 QQMKSIWDRYYKVDPSRKntkYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLPDVE 478
Cdd:COG4251 443 EYAEKIFEIFQRLHSRDE---YEGTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTLPKAP 502
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
373-475 |
9.10e-32 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 117.59 E-value: 9.10e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 373 QIMVNIIQNAIQFTENGQIMVTLEKGYLET-----IITIEDTGIGMSEQQMKSIWDRYYKVDPSRkNTKYGESGLGLPIV 447
Cdd:cd16922 3 QILLNLLGNAIKFTEEGEVTLRVSLEEEEEdgvqlRFSVEDTGIGIPEEQQARLFEPFSQADSST-TRKYGGTGLGLAIS 81
|
90 100
....*....|....*....|....*...
gi 1583047749 448 QQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16922 82 KKLVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
175-475 |
1.07e-31 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 124.91 E-value: 1.07e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 175 LFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQEN 254
Cdd:COG4191 52 LLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRELQE 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 255 RRRQ---------FMADASHEMRTPLTTINGLLEGLE--YNAIPENQR-ENAIKLMKNETERLIRLVNENLDYekIRTNQ 322
Cdd:COG4191 132 QLVQseklaalgeLAAGIAHEINNPLAAILGNAELLRrrLEDEPDPEElREALERILEGAERAAEIVRSLRAF--SRRDE 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 323 ISMviKKFNGTETLRNIVAQLEAKAEAAEDTLILKADDDID-VYADYDRFVQIMVNIIQNAIQFTE---NGQIMVTLEKG 398
Cdd:COG4191 210 EER--EPVDLNELIDEALELLRPRLKARGIEVELDLPPDLPpVLGDPGQLEQVLLNLLINAIDAMEegeGGRITISTRRE 287
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1583047749 399 YLETIITIEDTGIGMSEQQMKSIWDRYY--KvdPSRKNTkygesGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:COG4191 288 GDYVVISVRDNGPGIPPEVLERIFEPFFttK--PVGKGT-----GLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLP 359
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
215-481 |
1.17e-30 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 125.91 E-value: 1.17e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 215 NFDVQLPVHDKDEFDELADDFNKMTNSLKESQAEIE-----------------EQENRRR-QFMADASHEMRTPLTTING 276
Cdd:PRK15347 339 ALEPRLPENRLDELGSIAKAYNQLLDTLNEQYDTLEnkvaertqalaeakqraEQANKRKsEHLTTISHEIRTPLNGVLG 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 277 LLEGLEYNAIPENQRENAiklmknETER-----LIRLVNENLDYEKIRTNQISMVIKKfngTETLRNI-VAQLEAKAEAA 350
Cdd:PRK15347 419 ALELLQNTPLTAEQMDLA------DTARqctlsLLAIINNLLDFSRIESGQMTLSLEE---TALLPLLdQAMLTIQGPAQ 489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 351 EDTLILKA--DDDIDVYADYD--RFVQIMVNIIQNAIQFTENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYY 426
Cdd:PRK15347 490 SKSLTLRTfvGAHVPLYLHLDslRLRQILVNLLGNAVKFTETGGIRLRVKRHEQQLCFTVEDTGCGIDIQQQQQIFTPFY 569
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1583047749 427 KVDPSRKNTkygesGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLPDVEIKE 481
Cdd:PRK15347 570 QADTHSQGT-----GLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLPLNEYAP 619
|
|
| TMAO_torS |
TIGR02956 |
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the ... |
251-475 |
1.55e-28 |
|
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems]
Pssm-ID: 274362 [Multi-domain] Cd Length: 968 Bit Score: 119.88 E-value: 1.55e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 251 EQENR-RRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENAiKLMKNETERLIRLVNENLDYEKIRTNQISMVIKK 329
Cdd:TIGR02956 458 EEANRaKSAFLATMSHEIRTPLNGILGTLELLGDTGLTSQQQQYL-QVINRSGESLLDILNDILDYSKIEAGHLSISPRP 536
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 330 FNGTETLRNIVAQLEAKAEAAEDTLILKADDDIDVY--ADYDRFVQIMVNIIQNAIQFTENGQIMVTLE-KGYLETIITI 406
Cdd:TIGR02956 537 FDLNALLDDVHHLMVSRAQLKGIQLRLNIPEQLPNWwqGDGPRIRQVLINLVGNAIKFTDRGSVVLRVSlNDDSSLLFEV 616
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1583047749 407 EDTGIGMSEQQMKSIWDRYYKVDPSRKNtkyGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:TIGR02956 617 EDTGCGIAEEEQATLFDAFTQADGRRRS---GGTGLGLAISQRLVEAMDGELGVESELGVGSCFWFTLP 682
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
258-475 |
2.15e-28 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 116.51 E-value: 2.15e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 258 QFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQIsmviKKFNGTETLR 337
Cdd:COG5806 203 ELAASIAHEVRNPLTVVRGFIQLLQEPELSDEKRKQYIRIALEELDRAEAIITDYLTFAKPQPEKL----EKIDVSEELE 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 338 NIVAQLEAKAEAAEDTLILKADDDIDVYADYDRFVQIMVNIIQNAIQFTENG---QIMVTLEKGYLetIITIEDTGIGMS 414
Cdd:COG5806 279 HVIDVLSPYANMNNVEIQTELEPGLYIEGDRQKLQQCLINIIKNGIEAMPNGgtlTIDVSIDKNKV--IISIKDTGVGMT 356
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1583047749 415 EQQMKSIWDRYYkvdpsrkNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:COG5806 357 KEQLERLGEPYF-------STKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTTFTITLP 410
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
366-475 |
2.35e-28 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 108.22 E-value: 2.35e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 366 ADYDRFVQIMVNIIQNAIQFT-ENGQIMVTLEKGYlETIITIEDTGIGMSEQQMKSIWDRYYKVDpsrkNTKYGESGLGL 444
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAaKAGEITVTLSEGG-ELTLTVEDNGIGIPPEDLPRIFEPFSTAD----KRGGGGTGLGL 75
|
90 100 110
....*....|....*....|....*....|.
gi 1583047749 445 PIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:pfam02518 76 SIVRKLVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
242-475 |
3.30e-28 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 117.00 E-value: 3.30e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 242 LKESQAEIEEQE--NRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRenAIKLMKNETERLIRLVNENLDYEKIR 319
Cdd:COG5809 254 RKKLEELLRKSEklSVVGELAAGIAHEIRNPLTSLKGFIQLLKDTIDEEQKT--YLDIMLSELDRIESIISEFLVLAKPQ 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 320 tnqiSMVIKKFNGTETLRNIVAQLEAKAeaaedtlILK--------ADDDIDVYADYDRFVQIMVNIIQNAIQFTENGQi 391
Cdd:COG5809 332 ----AIKYEPKDLNTLIEEVIPLLQPQA-------LLKnvqielelEDDIPDILGDENQLKQVFINLLKNAIEAMPEGG- 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 392 MVTLEKGYLE---TIITIEDTGIGMSEQQMKSIWDRYYkvdpsrkNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGT 468
Cdd:COG5809 400 NITIETKAEDddkVVISVTDEGCGIPEERLKKLGEPFY-------TTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGT 472
|
....*..
gi 1583047749 469 KFTVRLP 475
Cdd:COG5809 473 TFSITLP 479
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
237-475 |
4.57e-27 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 115.07 E-value: 4.57e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 237 KMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQrENAIKLMKNETERLIRLVNENLDYE 316
Cdd:PRK10841 428 KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGV-DRLVTAMNNSSSLLLKIISDILDFS 506
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 317 KIRTNQISMVIKKFNGTETLRNIVAQLEAKAEAAEDTLILKADDDIDVYADYD--RFVQIMVNIIQNAIQFTENGQIM-- 392
Cdd:PRK10841 507 KIESEQLKIEPREFSPREVINHITANYLPLVVKKRLGLYCFIEPDVPVALNGDpmRLQQVISNLLSNAIKFTDTGCIVlh 586
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 393 VTLEKGYLEtiITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGeSGLGLPIVQQLVRLHKGKLEVESELGKGTKFTV 472
Cdd:PRK10841 587 VRVDGDYLS--FRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQG-TGLGLAICEKLINMMDGDISVDSEPGMGSQFTI 663
|
...
gi 1583047749 473 RLP 475
Cdd:PRK10841 664 RIP 666
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
153-475 |
6.15e-27 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 113.02 E-value: 6.15e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 153 GALVVSQPARN----IDNSVRPItlnLFKGFIFSSIVAVIASyAFAAFQVKRINRLRNATKEVTNGNfDVQLPVHDKDEF 228
Cdd:PRK11100 162 GVLSVGKPNSSmapfIKRSERRI---LWAGALLLGIALLIGA-GVVWWLNRSIRRLTRYADAVTEGK-PVPLPKLGSSEL 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 229 DELADDFNKMTNSLkESQAEIEeqenrrrQFMADASHEMRTPLTTINGLLEGLEyNAIPENQRENAIKLMKNETERLIRL 308
Cdd:PRK11100 237 RELAQALESMRVKL-EGKAYVE-------QYVQTLTHELKSPLAAIRGAAELLQ-EDPPPEDRARFTGNILTQSARLQQL 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 309 VNENLDYEKIRTNQISMVIKKFNGTETLRNIVAQLEAKAEAAEDTLILKADDdIDVYADYDRFVQIMVNIIQNAIQFT-E 387
Cdd:PRK11100 308 IDRLLELARLEQRQELEVLEPVALAALLEELVEAREAQAAAKGITLRLRPDD-ARVLGDPFLLRQALGNLLDNAIDFSpE 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 388 NGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVdpSRKNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKG 467
Cdd:PRK11100 387 GGTITLSAEVDGEQVALSVEDQGPGIPDYALPRIFERFYSL--PRPANGRKSTGLGLAFVREVARLHGGEVTLRNRPEGG 464
|
....*...
gi 1583047749 468 TKFTVRLP 475
Cdd:PRK11100 465 VLATLTLP 472
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
256-482 |
2.35e-25 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 110.21 E-value: 2.35e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 256 RRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTET 335
Cdd:PRK09959 712 KSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTL 791
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 336 LRNIVAQLEAKAEAAEDTLILKAD--DDIDVYADYDRFVQIMVNIIQNAIQFTENGQIMVT-----LEKGYLETIITIED 408
Cdd:PRK09959 792 VQNTCHSFGAIAASKSIALSCSSTfpDHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITtslghIDDNHAVIKMTIMD 871
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1583047749 409 TGIGMSEQQMKSIWDRYYKVDPSRKNTKygeSGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLPdVEIKEE 482
Cdd:PRK09959 872 SGSGLSQEEQQQLFKRYSQTSAGRQQTG---SGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIP-VEISQQ 941
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
187-475 |
3.19e-25 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 108.32 E-value: 3.19e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 187 VIASYAFAAFQVKR-INRLRNATKEVTNGNFDVQL-PVHDKDEFDELADDFNKMTnslkesqAEIEEQENRRRQFMADAS 264
Cdd:PRK09835 198 IVFIVLLAVHKGHApIRSVSRQIQNITSKDLDVRLdPQTVPIELEQLVLSFNHMI-------ERIEDVFTRQSNFSADIA 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 265 HEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTETLRNIVAQLE 344
Cdd:PRK09835 271 HEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLDLADEVGKVFDFFE 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 345 AKAEAAEDTLILKADDDIdVYADYDRFVQIMVNIIQNAIQFTENGQ-IMVTLEKGYLETIITIEDTGIGMSEQQMKSIWD 423
Cdd:PRK09835 351 AWAEERGVELRFVGDPCQ-VAGDPLMLRRAISNLLSNALRYTPAGEaITVRCQEVDHQVQLVVENPGTPIAPEHLPRLFD 429
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1583047749 424 RYYKVDPSRKNTKYGeSGLGLPIVQQLVRLHKGKLEVESELgKGTKFTVRLP 475
Cdd:PRK09835 430 RFYRVDPSRQRKGEG-SGIGLAIVKSIVVAHKGTVAVTSDA-RGTRFVISLP 479
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
252-482 |
3.38e-24 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 105.82 E-value: 3.38e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 252 QENRRRQ--------FMADASHEMRTPLTTINGLLEGL-EYNAIPENQRenAIKLMKNETERLIRLVNENLDYEkiRTNQ 322
Cdd:PRK11360 378 QRRVARQerlaalgeLVAGVAHEIRNPLTAIRGYVQIWrQQTSDPPSQE--YLSVVLREVDRLNKVIDQLLEFS--RPRE 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 323 ISMVIKKFNgteTLRNIVAQLEAKAEAAED-TLILKADDDID-VYADYDRFVQIMVNIIQNAIQ-FTENGQIMVTLEK-G 398
Cdd:PRK11360 454 SQWQPVSLN---ALVEEVLQLFQTAGVQARvDFETELDNELPpIWADPELLKQVLLNILINAVQaISARGKIRIRTWQyS 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 399 YLETIITIEDTGIGMSEQQMKSIWDRYYkvdpsrkNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLPDVE 478
Cdd:PRK11360 531 DGQVAVSIEDNGCGIDPELLKKIFDPFF-------TTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLPINP 603
|
....
gi 1583047749 479 IKEE 482
Cdd:PRK11360 604 QGNQ 607
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
244-475 |
1.78e-23 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 102.56 E-value: 1.78e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 244 ESQAEIEEQENRRRQFMA------DASHEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLdyEK 317
Cdd:PRK10364 219 RSRQLLQDEMKRKEKLVAlghlaaGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELL--EL 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 318 IRTNQISMVIKKFNgteTLRNIVAQL-EAKAEAAEDTLILKADDDID-VYADYDRFVQIMVNIIQNAIQ-FTENGQIMVT 394
Cdd:PRK10364 297 VKPTHLALQAVDLN---DLINHSLQLvSQDANSREIQLRFTANDTLPeIQADPDRLTQVLLNLYLNAIQaIGQHGVISVT 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 395 LEKGYLETIITIEDTGIGMSEQQMKSIWDRYYkvdpsrkNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRL 474
Cdd:PRK10364 374 ASESGAGVKISVTDSGKGIAADQLEAIFTPYF-------TTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWL 446
|
.
gi 1583047749 475 P 475
Cdd:PRK10364 447 P 447
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
243-475 |
4.67e-23 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 103.06 E-value: 4.67e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 243 KESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENaIKLMKNETERLIRLVNENLDYEKIRTNQ 322
Cdd:PRK11466 431 RQARAEAEKASQAKSAFLAAMSHEIRTPLYGILGTAQLLADNPALNAQRDD-LRAITDSGESLLTILNDILDYSAIEAGG 509
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 323 ISMVI--KKFNGTETLRNIVAQLEAKAEAAEDTLILKADDDIDVY--ADYDRFVQIMVNIIQNAIQFTENGQIMVTLEKG 398
Cdd:PRK11466 510 KNVSVsdEPFEPRPLLESTLQLMSGRVKGRPIRLATDIADDLPTAlmGDPRRIRQVITNLLSNALRFTDEGSIVLRSRTD 589
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1583047749 399 YLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRkntkyGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:PRK11466 590 GEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKR-----GGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLP 661
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
258-475 |
5.20e-23 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 101.73 E-value: 5.20e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 258 QFMADASHEMRTPLTTINGLLEGLEYNaipENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQIsmviKKFNGTETLR 337
Cdd:COG5805 289 QLAAGIAHEIRNPLTSIKGFLQLLQPG---IEDKEEYFDIMLSELDRIESIISEFLALAKPQAVNK----EKENINELIQ 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 338 NIVAQLEAKAEAAEDTLILKA-DDDIDVYADYDRFVQIMVNIIQNAIQFTEN-GQIMVTLEKGYLETIITIEDTGIGMSE 415
Cdd:COG5805 362 DVVTLLETEAILHNIQIRLELlDEDPFIYCDENQIKQVFINLIKNAIEAMPNgGTITIHTEEEDNSVIIRVIDEGIGIPE 441
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 416 QQMKSIWDRYYkvdpsrkNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:COG5805 442 ERLKKLGEPFF-------TTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLP 494
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
2-475 |
2.46e-21 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 96.54 E-value: 2.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 2 RYLYQQLLAFCGMVALILLIVGVSFTQL-TKQ--TIEENNYQQLFGYAESVEKttqtyadtlpQFSQDQAFQNALLLTEQ 78
Cdd:PRK09470 7 NSLTARIFAIFWLTLALVLMLVLMLPKLdSRQmtELLDSEQRQGLMIEQHIEA----------ELANDPPNDLMWWRRLF 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 79 VLTEQ----NVNFIFIDKNERVI---YPTNTALLNFTLTTDqwkNLRSGRQEKFtSNKNILGqaqatsyalvPF-----N 146
Cdd:PRK09470 77 RAIDKwappGQRLLLVTSEGRIIgaeRSEMQAVRNFIGQSD---NADHPQKKKY-GRVEIVG----------PFsvrdgE 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 147 LNHEFYGALVVSQPARNIDNSV--RPITLnLFKGFIFSSIVAVIASYAFAafqvKRINRLRNATKEVTNGNFdvqlpVHD 224
Cdd:PRK09470 143 DNYQLYLIRPANSPQSDFINLLfdRPLLL-LLVTMLVSTPLLLWLAWSLA----KPARKLKNAADEVAQGNL-----RQH 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 225 KD------EFDELADDFNKMTNSLkesqaeiEEQENRRRQFMADASHEMRTPLTTI---NGLL-----EGleynaiPENQ 290
Cdd:PRK09470 213 PEletgpqEFRQAGASFNQMVTAL-------ERMMTSQQRLLSDISHELRTPLTRLqlaTALLrrrqgES------KELE 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 291 RenaiklMKNETERLIRLVNENLDYEKIRTNQiSMVIKKFNGTETLRNIVAqlEAKAEAAEDTLILKADDDIDVYADYDR 370
Cdd:PRK09470 280 R------IETEAQRLDSMINDLLVLSRNQQKN-HLERETFKANSLWSEVLE--DAKFEAEQMGKSLTVSAPPGPWPINGN 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 371 FVQIMV---NIIQNAIQFTENG-QIMVTLEKGYLetIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKyGESGLGLPI 446
Cdd:PRK09470 351 PNALASaleNIVRNALRYSHTKiEVAFSVDKDGL--TITVDDDGPGVPEEEREQIFRPFYRVDEARDRES-GGTGLGLAI 427
|
490 500 510
....*....|....*....|....*....|
gi 1583047749 447 VQQLVRLHKGKLEVE-SELGkGTKFTVRLP 475
Cdd:PRK09470 428 VENAIQQHRGWVKAEdSPLG-GLRLTIWLP 456
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
162-475 |
4.32e-20 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 91.57 E-value: 4.32e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 162 RNIDNSVRPITLNLfkgfIFSSIVAVIASYAFAAFQVKRINR-LRNATKEVTNGNFDVQLPVHDKDEFDELAddfnKMTN 240
Cdd:PRK10755 50 EHVMKEIREAVASL----LVPSLVMVSLTLLICFQAVRWITRpLAELQKELEARTADNLTPIAIHSSTLEIE----AVTS 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 241 SLKESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQ----RenaIKLMKNETERLIRLVnenldye 316
Cdd:PRK10755 122 ALNQLVSRLTSTLDQERLFTADVAHELRTPLAGIRLHLELLEKQHHIDVApliaR---LDQMMHTVEQLLQLA------- 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 317 kiRTNQiSMVIKKFNGTETLRNIV----AQLEAKAEAAEDTLILK-ADDDIDVYADyDRFVQIMV-NIIQNAIQFT-ENG 389
Cdd:PRK10755 192 --RAGQ-SFSSGHYQTVKLLEDVIlpsqDELSEMLEQRQQTLLLPeSAADITVQGD-ATLLRLLLrNLVENAHRYSpEGS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 390 QIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDpsrknTKYGESGLGLPIVQQLVRLHKGKLEVESEL-GKGT 468
Cdd:PRK10755 268 TITIKLSQEDGGAVLAVEDEGPGIDESKCGELSKAFVRMD-----SRYGGIGLGLSIVSRITQLHHGQFFLQNRQeRSGT 342
|
....*..
gi 1583047749 469 KFTVRLP 475
Cdd:PRK10755 343 RAWVWLP 349
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
259-475 |
5.87e-20 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 93.38 E-value: 5.87e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 259 FMADASHEMRTPLTTINGLLEGLEYNAIPENQRE--NAIklmknetER----LIRLVNENLDYEKIRTNQisMVIKK--F 330
Cdd:PRK11107 296 FLANMSHELRTPLNGVIGFTRQTLKTPLTPTQRDylQTI-------ERsannLLAIINDILDFSKLEAGK--LVLENipF 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 331 NGTETLRNIVAQLEAKAEAAEDTLILKADDDI--DVYADYDRFVQIMVNIIQNAIQFTENGQIMVTLEKGYLE----TI- 403
Cdd:PRK11107 367 SLRETLDEVVTLLAHSAHEKGLELTLNIDPDVpdNVIGDPLRLQQIITNLVGNAIKFTESGNIDILVELRALSntkvQLe 446
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1583047749 404 ITIEDTGIGMSEQQMKSIWDRYYKVDPS--RkntKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:PRK11107 447 VQIRDTGIGISERQQSQLFQAFRQADASisR---RHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHLP 517
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
243-482 |
7.62e-20 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 92.70 E-value: 7.62e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 243 KESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQReNAIKLMKNETERLIRLVNENLDYEKIRTNQ 322
Cdd:PRK11091 270 KRYQDALEKASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQR-KYLKTIHVSAITLGNIFNDIIDMDKMERRK 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 323 ISMVIKKFNGT---ETLRNIVAQLeakAEAAEDTLILKADDDID--VYADYDRFVQIMVNIIQNAIQFTENGQIMVTLEK 397
Cdd:PRK11091 349 LQLDNQPIDFTdflADLENLSGLQ---AEQKGLRFDLEPLLPLPhkVITDGTRLRQILWNLISNAVKFTQQGGVTVRVRY 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 398 GYLETI-ITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLPD 476
Cdd:PRK11091 426 EEGDMLtFEVEDSGIGIPEDELDKIFAMYYQVKDSHGGKPATGTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIHA 505
|
....*.
gi 1583047749 477 VEIKEE 482
Cdd:PRK11091 506 PAVAEE 511
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
248-475 |
1.17e-19 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 90.68 E-value: 1.17e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 248 EIEEQENRRRQF--MADA----SHEMRTPLTTINGLLEGLEYnaipenqrENAIKLMKNETERLIRLVNENLDYEKIRTn 321
Cdd:COG3290 175 ELERLEEELEGVkeLAEAlraqRHDFRNHLHTISGLLQLGEY--------DEALEYIDEISEELQELIDSLLSRIGNPV- 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 322 qismvikkfngtetlrnIVAQLEAKAEAAED---TLILKADDDIDVY--ADYDrFVQIMVNIIQNAI-----QFTENGQI 391
Cdd:COG3290 246 -----------------LAALLLGKAARARErgiDLTIDIDSDLPDLplSDTD-LVTILGNLLDNAIeavekLPEEERRV 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 392 MVTL--EKGYLetIITIEDTGIGMSEQQMKSIWDRYYkvdpsrkNTKYGE-SGLGLPIVQQLVRLHKGKLEVESELGKGT 468
Cdd:COG3290 308 ELSIrdDGDEL--VIEVEDSGPGIPEELLEKIFERGF-------STKLGEgRGLGLALVKQIVEKYGGTIEVESEEGEGT 378
|
....*..
gi 1583047749 469 KFTVRLP 475
Cdd:COG3290 379 VFTVRLP 385
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
155-475 |
2.67e-19 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 90.08 E-value: 2.67e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 155 LVVSQPARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFdVQLPVHDKDEFDELADD 234
Cdd:COG2972 139 LVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDL-VRLEVSGNDEIGILARS 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 235 FNKMTNSLKESQAEIEEQENRRRqfmadashEMRtplttinglLEGLE--------YNAIpenqreNAIKLM--KNETER 304
Cdd:COG2972 218 FNEMVERIKELIEEVYELELEKK--------EAE---------LKALQaqinphflFNTL------NSIRWLaeLEDPEE 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 305 LIRLVNENLDYEKIRTNQISMVIKkfngtetlrnivaqLEAKAEAAEDTLILK---ADDDIDVYADYD---RFVQIMVNI 378
Cdd:COG2972 275 AEEMLEALSKLLRYSLSKGDELVT--------------LEEELELIKSYLEIQklrFGDRLEVEIEIDeelLDLLIPKLI 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 379 IQ----NAI-----QFTENGQIMVT--LEKGYLetIITIEDTGIGMSEQQMKSIWDRYykvdpsrkNTKYGESGLGLPIV 447
Cdd:COG2972 341 LQplveNAIehgiePKEGGGTIRISirKEGDRL--VITVEDNGVGMPEEKLEKLLEEL--------SSKGEGRGIGLRNV 410
|
330 340 350
....*....|....*....|....*....|.
gi 1583047749 448 QQLVRLHKGK---LEVESELGKGTKFTVRLP 475
Cdd:COG2972 411 RERLKLYYGEeygLEIESEPGEGTTVTIRIP 441
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
242-475 |
1.02e-18 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 87.70 E-value: 1.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 242 LKESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQ------RENAIKLMKNETERLIRLVNENLDY 315
Cdd:PRK09303 137 LRQENETLLEQLKFKDRVLAMLAHDLRTPLTAASLALETLELGQIDEDTelkpalIEQLQDQARRQLEEIERLITDLLEV 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 316 EKIRTNQIsmvikKFNGTET-LRNIVA----QLEAKAEAAEDTLILKADDDI-DVYADYDRFVQIMVNIIQNAIQFT-EN 388
Cdd:PRK09303 217 GRTRWEAL-----RFNPQKLdLGSLCQevilELEKRWLAKSLEIQTDIPSDLpSVYADQERIRQVLLNLLDNAIKYTpEG 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 389 GQIMVT-LEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGesgLGLPIVQQLVRLHKGKLEVESELGKG 467
Cdd:PRK09303 292 GTITLSmLHRTTQKVQVSICDTGPGIPEEEQERIFEDRVRLPRDEGTEGYG---IGLSVCRRIVRVHYGQIWVDSEPGQG 368
|
....*...
gi 1583047749 468 TKFTVRLP 475
Cdd:PRK09303 369 SCFHFTLP 376
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
373-475 |
1.17e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 81.31 E-value: 1.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 373 QIMVNIIQNAIQ-FTENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTkygesGLGLPIVQQLV 451
Cdd:cd16943 6 QVLLNLLVNAAQaMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGEGT-----GLGLSLSYRII 80
|
90 100
....*....|....*....|....
gi 1583047749 452 RLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16943 81 QKHGGTIRVASVPGGGTRFTIILP 104
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
361-474 |
7.86e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 78.99 E-value: 7.86e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 361 DIDVYADYDRFVQIMVNIIQNAIQFT-ENGQIMVTLEkGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPsrknTKYGE 439
Cdd:cd16940 4 DIQVQGDALLLFLLLRNLVDNAVRYSpQGSRVEIKLS-ADDGAVIRVEDNGPGIDEEELEALFERFYRSDG----QNYGG 78
|
90 100 110
....*....|....*....|....*....|....*
gi 1583047749 440 SGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRL 474
Cdd:cd16940 79 SGLGLSIVKRIVELHGGQIFLGNAQGGGLEAWVRL 113
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
367-475 |
2.44e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 77.50 E-value: 2.44e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 367 DYDRFVQIMVNIIQNAIQFTENG---QIMVTLEKGYLEtiITIEDTGIGMSEQQMKSIWDRYYKVDPSRkNTKYGESGLG 443
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGgklRIRAAQTPQEVR--LDVEDSAPGVSDDQLARLFERFYRVESSR-NRASGGSGLG 77
|
90 100 110
....*....|....*....|....*....|...
gi 1583047749 444 LPIVQQLVRLHKGKLEVE-SELGkGTKFTVRLP 475
Cdd:cd16946 78 LAICHNIALAHGGTISAEhSPLG-GLRLVLTLP 109
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
377-475 |
3.16e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 77.24 E-value: 3.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 377 NIIQNAIQFT-ENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGeSGLGLPIVQQLVRLHK 455
Cdd:cd16952 7 NLVSNAVKYTpPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGG-TGLGLAIVKHVMSRHD 85
|
90 100
....*....|....*....|
gi 1583047749 456 GKLEVESELGKGTKFTVRLP 475
Cdd:cd16952 86 ARLLIASELGKGSRFTCLFP 105
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
367-475 |
4.73e-17 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 76.76 E-value: 4.73e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 367 DYDRFVQIMVNIIQNAIQFT-ENGQIMVTLEKGYLETI-ITIEDTGIGMSEQQMKSIWDRYYKVDPSrKNTKYGESGLGL 444
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTpDGGRIRCILEKFRLNRFlLTVSDSGPGIPPNLREEIFERFRQGDGS-STRAHGGTGLGL 79
|
90 100 110
....*....|....*....|....*....|.
gi 1583047749 445 PIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16925 80 SIVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
371-475 |
3.50e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 74.25 E-value: 3.50e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 371 FVQIMVNIIQNAI-----QFTENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYkvdpSRKNTkyGESGLGLP 445
Cdd:cd16915 1 LITIVGNLIDNALdalaaTGAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGV----STKGQ--GERGIGLA 74
|
90 100 110
....*....|....*....|....*....|
gi 1583047749 446 IVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16915 75 LVRQSVERLGGSITVESEPGGGTTFSIRIP 104
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
372-475 |
3.78e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 73.90 E-value: 3.78e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 372 VQIMVNIIQNAIQFT---ENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPsrkNTKYGESGLGLPIVQ 448
Cdd:cd16921 2 GQVLTNLLGNAIKFRrprRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHS---REEYEGTGVGLAIVR 78
|
90 100
....*....|....*....|....*..
gi 1583047749 449 QLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16921 79 KIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| marine_sort_HK |
TIGR03785 |
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is ... |
141-475 |
6.31e-16 |
|
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is paired with an adjacent response regulator (TIGR03787) gene. It co-occurs with a variant sortase enzyme (TIGR03784), usually in the same gene neighborhood, in proteobacterial species most of which are marine, and with an LPXTG motif-containing sortase target conserved protein (TIGR03788). Sortases and LPXTG proteins are far more common in Gram-positive bacteria, where sortase systems mediate attachment to the cell wall or cross-linking of pilin structures. We give this predicted sensor histidine kinase the gene symbol psdS, for Proteobacterial Dedicated Sortase system Sensor histidine kinase.
Pssm-ID: 163497 [Multi-domain] Cd Length: 703 Bit Score: 80.56 E-value: 6.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 141 ALVPFNLNHEFYGALVVSQPARNIdNSVRPITLN-LFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEV--TNGNFD 217
Cdd:TIGR03785 374 AAYPIWIDTEVLGAVIAEQTTNGI-RTLRNSALEkLFNVILAIMSIGTLALFGFASWISWRIRRLSDDAEAAidSQGRIS 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 218 VQLPVHD-KDEFDELADDFNKMTNSLKESQAEIEEQENRrrqfmadASHEMRTPLTTINGLLEGLEYNAIpENQRENAIK 296
Cdd:TIGR03785 453 GAIPASRsRDEIGDLSRSFAQMVARLRQYTHYLENMSSR-------LSHELRTPVAVVRSSLENLELQAL-EQEKQKYLE 524
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 297 LMKNETERLIRLVN------------ENLDYEKIRTNQismVIKKFngTETLRNIVAQLEAKAEAAEDTLILKADDDIdv 364
Cdd:TIGR03785 525 RAREGTERLSMILNnmseatrleqaiQSAEVEDFDLSE---VLSGC--MQGYQMTYPPQRFELNIPETPLVMRGSPEL-- 597
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 365 yadydrFVQIMVNIIQNAIQFT-ENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYgESGLG 443
Cdd:TIGR03785 598 ------IAQMLDKLVDNAREFSpEDGLIEVGLSQNKSHALLTVSNEGPPLPEDMGEQLFDSMVSVRDQGAQDQP-HLGLG 670
|
330 340 350
....*....|....*....|....*....|...
gi 1583047749 444 LPIVQQLVRLHKGKLEVESEL-GKGTKFTVRLP 475
Cdd:TIGR03785 671 LYIVRLIADFHQGRIQAENRQqNDGVVFRISLP 703
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
372-475 |
9.84e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 72.99 E-value: 9.84e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 372 VQIMVNIIQNAIQFT--ENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPsrKNTKYGE-SGLGLPIVQ 448
Cdd:cd16953 2 GQVLRNLIGNAISFSppDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERP--ANEAFGQhSGLGLSISR 79
|
90 100 110
....*....|....*....|....*....|.
gi 1583047749 449 QLVRLHKGKLEVES----ELGKGTKFTVRLP 475
Cdd:cd16953 80 QIIEAHGGISVAENhnqpGQVIGARFTVQLP 110
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
253-317 |
3.72e-15 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 69.93 E-value: 3.72e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1583047749 253 ENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEK 317
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
231-475 |
6.43e-15 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 77.38 E-value: 6.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 231 LADDFNKMTNSLKESQAEIE-EQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPEN----QRENAIKlmkNETERL 305
Cdd:PRK10490 638 IANALERLTLTASEEQARLAsEREQLRNALLAALSHDLRTPLTVLFGQAEILTLDLASEGsphaRQASEIR---QQVLNT 714
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 306 IRLVNENLDYEKIRTNQISMViKKFNgteTLRNIV----AQLEAKAEAAEDTLILKADDDIdVYADYDRFVQIMVNIIQN 381
Cdd:PRK10490 715 TRLVNNLLDMARIQSGGFNLR-KEWL---TLEEVVgsalQMLEPGLSGHPINLSLPEPLTL-IHVDGPLFERVLINLLEN 789
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 382 AIQFTENGQ---IMVTLEKGYLEtiITIEDTGIGMSEQQMKSIWDRYykvdpSRKNTkygES-----GLGLPIVQQLVRL 453
Cdd:PRK10490 790 AVKYAGAQAeigIDAHVEGERLQ--LDVWDNGPGIPPGQEQLIFDKF-----ARGNK---ESaipgvGLGLAICRAIVEV 859
|
250 260
....*....|....*....|..
gi 1583047749 454 HKGKLEVESELGKGTKFTVRLP 475
Cdd:PRK10490 860 HGGTIWAENRPEGGACFRVTLP 881
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
255-321 |
1.10e-14 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 68.36 E-value: 1.10e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1583047749 255 RRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQREnAIKLMKNETERLIRLVNENLDYEKIRTN 321
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEEQRE-YLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
255-321 |
1.33e-14 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 68.39 E-value: 1.33e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1583047749 255 RRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQREnAIKLMKNETERLIRLVNENLDYEKIRTN 321
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQRE-YLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
371-475 |
1.98e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 68.89 E-value: 1.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 371 FVQIMVNIIQNAIQFTeNGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRkNTKYGESGLGLPIVQQL 450
Cdd:cd16949 1 LARALENVLRNALRYS-PSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSAR-DRESGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*
gi 1583047749 451 VRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
361-474 |
2.56e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 69.46 E-value: 2.56e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 361 DIDVYA--DYDRFVQIMVNIIQNAIQFTENGQIM-VTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKY 437
Cdd:cd16947 9 DRPIYAnaNTEALQRILKNLISNAIKYGSDGKFLgMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSRNSAKQ 88
|
90 100 110
....*....|....*....|....*....|....*..
gi 1583047749 438 GeSGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRL 474
Cdd:cd16947 89 G-NGLGLTITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
367-473 |
4.51e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 68.26 E-value: 4.51e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 367 DYDRFVQIMVNIIQNAIQFTENG---QIMVTLEKGYLEtiITIEDTGIGMSEQQMKSIWDRYYKVDPSRknTKYGESGLG 443
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGgtvSISIYDEEEYLY--FEIWDNGHGFSEQDLKKALELFYRDDTSR--RSGGHYGMG 76
|
90 100 110
....*....|....*....|....*....|
gi 1583047749 444 LPIVQQLVRLHKGKLEVESELGKGTKFTVR 473
Cdd:cd16975 77 LYIAKNLVEKHGGSLIIENSQKGGAEVTVK 106
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
179-412 |
1.28e-13 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 72.61 E-value: 1.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 179 FIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQ 258
Cdd:COG3850 124 LLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELYAELEEEEELEAE 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 259 FMADASHEMRTPLTTINGLLEGLEynaIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTETLRN 338
Cdd:COG3850 204 LELLALLDELLLLAALLLLLALLL---ALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLASALLL 280
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1583047749 339 IVAQLEAKAEAAEDTLILKADDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIMVTLEKGYLETIITIEDTGIG 412
Cdd:COG3850 281 LELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAALE 354
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
350-475 |
1.35e-13 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 73.02 E-value: 1.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 350 AEDTLILKADDDiDVYADydrFVQIMVNIIQNAIQF---TENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYY 426
Cdd:PRK11086 417 SEDSQLPDSGDE-DQVHE---LITILGNLIENALEAvggEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGY 492
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1583047749 427 kvdpsrkNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:PRK11086 493 -------STKGSNRGVGLYLVKQSVENLGGSIAVESEPGVGTQFFVQIP 534
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
301-475 |
2.27e-13 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 72.40 E-value: 2.27e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 301 ETERLIRLVNENLDYEKIRtnqiSMVIKKFNGTETLRNIVAQLEAkAEAAEDTLILKADDDID-VYADYDRFVQIMVNII 379
Cdd:PRK13837 495 AGARARLIIDQILAFGRKG----ERNTKPFDLSELVTEIAPLLRV-SLPPGVELDFDQDQEPAvVEGNPAELQQVLMNLC 569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 380 QNAIQ-FTENGQIMVTLEKGYLET---------------IITIEDTGIGMSEQQMKSIWDRYYkvdpsrkNTKYGESGLG 443
Cdd:PRK13837 570 SNAAQaMDGAGRVDISLSRAKLRApkvlshgvlppgryvLLRVSDTGAGIDEAVLPHIFEPFF-------TTRAGGTGLG 642
|
170 180 190
....*....|....*....|....*....|..
gi 1583047749 444 LPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:PRK13837 643 LATVHGIVSAHAGYIDVQSTVGRGTRFDVYLP 674
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
203-475 |
2.74e-13 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 71.56 E-value: 2.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 203 RLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSlkesqaeIEEQENRRRQFMADASHEMRTPLTTINGLLEGLE 282
Cdd:PRK10604 166 KLEAAAQRLGDGHLAERIHFDEGSSLERLGVAFNQMADN-------INALIASKKQLIDGIAHELRTPLVRLRYRLEMSD 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 283 YNAIPENQRENaiklmkNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTETLRNIVAQLEAKAEAAEDTLILKADDDI 362
Cdd:PRK10604 239 NLSAAESQALN------RDIGQLEALIEELLTYARLDRPQNELHLSEPDLPAWLSTHLADIQAVTPEKTVRLDTPHQGDY 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 363 dVYADYDRFVQIMVNIIQNAIQFTEnGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRkNTKYGESGL 442
Cdd:PRK10604 313 -GALDMRLMERVLDNLLNNALRYAH-SRVRVSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSR-DRATGGCGL 389
|
250 260 270
....*....|....*....|....*....|....
gi 1583047749 443 GLPIVQQLVRLHKGKLEVE-SELGkGTKFTVRLP 475
Cdd:PRK10604 390 GLAIVHSIALAMGGSVNCDeSELG-GARFSFSWP 422
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
240-454 |
9.77e-13 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 70.06 E-value: 9.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 240 NSLKESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMKNETERLIRLVNE-----NLD 314
Cdd:PRK10337 221 EALNQLFARTHAMMVRERRFTSDAAHELRSPLAALKVQTEVAQLSDDDPQARKKALLQLHAGIDRATRLVDQlltlsRLD 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 315 YEKIR--TNQISMvikkfngTETLRNIVAQLEAKAEAAEDTLILKADDDIDVYADYDRFVQIMV-NIIQNAIQFTENG-Q 390
Cdd:PRK10337 301 SLDNLqdVAEIPL-------EDLLQSAVMDIYHTAQQAGIDVRLTLNAHPVIRTGQPLLLSLLVrNLLDNAIRYSPQGsV 373
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1583047749 391 IMVTLEKGYLetiiTIEDTGIGMSEQQMKSIWDRYYKvDPSRKNTKygeSGLGLPIVQQLVRLH 454
Cdd:PRK10337 374 VDVTLNARNF----TVRDNGPGVTPEALARIGERFYR-PPGQEATG---SGLGLSIVRRIAKLH 429
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
378-475 |
1.10e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 64.23 E-value: 1.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 378 IIQNAIQFT-ENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKygESGLGLPIVQQLV-RLHK 455
Cdd:cd16948 13 IVSNALKYSkQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRNFQE--STGMGLYLVKKLCdKLGH 90
|
90 100
....*....|....*....|
gi 1583047749 456 gKLEVESELGKGTKFTVRLP 475
Cdd:cd16948 91 -KIDVESEVGEGTTFTITFP 109
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
373-460 |
1.16e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 64.02 E-value: 1.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 373 QIMVNIIQNAIQFT-ENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVdpSRKNTKYGESGLGLPIVQQLV 451
Cdd:cd16945 7 QAINNLLDNAIDFSpEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSL--PRPHSGQKSTGLGLAFVQEVA 84
|
....*....
gi 1583047749 452 RLHKGKLEV 460
Cdd:cd16945 85 QLHGGRITL 93
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
170-475 |
1.75e-12 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 69.17 E-value: 1.75e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 170 PITLNLfkgfIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKEsqaei 249
Cdd:PRK09467 154 PLFRYT----LAIGLLSVAGGWLFIRIQNRPLVALEHAALQVGKGEIPPPLREYGASEVRSVTRAFNQMAAGIKQ----- 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 250 eeQENRRRQFMADASHEMRTPLTTINGLLEGLeynaIPENQ--RENAIKlmknETERLIRLVNENLDYekIRTNQ-ISMV 326
Cdd:PRK09467 225 --LEDDRTLLMAGVSHDLRTPLTRIRLATEMM----SEEDGylAESINK----DIEECNAIIEQFIDY--LRTGQeMPME 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 327 IKKFNgteTLRNIVAQLEAKAEAAEDTLILKADDDIDVYAdydrfVQI---MVNIIQNAIQFTeNGQIMVTL--EKGYLe 401
Cdd:PRK09467 293 MADLN---ALLGEVIAAESGYEREIETALQPGPIEVPMNP-----IAIkraLANLVVNAARYG-NGWIKVSSgtEGKRA- 362
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1583047749 402 tIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKygeSGLGLPIVQQLVRLHKGKLEV-ESELGkGTKFTVRLP 475
Cdd:PRK09467 363 -WFQVEDDGPGIPPEQLKHLFQPFTRGDSARGSSG---TGLGLAIVKRIVDQHNGKVELgNSEEG-GLSARAWLP 432
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
180-467 |
3.76e-12 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 68.56 E-value: 3.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 180 IFSSIVAVIASYAFAAFQV-----KRINRLRNATKEVTNGNFDVQLPVHDKDEFDELA---DDFNKMTNSLKES-QAEIE 250
Cdd:COG4192 329 LAIALLSLLLAVLINYFYVrrrlvKRLNALSDAMAAIAAGDLDVPIPVDGNDEIGRIArllRVFRDQAIEKTQElETEIE 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 251 EQ---ENRRR----------------QFMADASHEMRTPLTTINGLLEGLEYNAIPEN--QRENAIKLMKNETERLIRLV 309
Cdd:COG4192 409 ERkriEKNLRqtqdeliqaakmavvgQTMTSLAHELNQPLNAMSMYLFSAKKALEQENyaQLPTSLDKIEGLIERMDKII 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 310 NeNLDYEKIRTNQiSMVIKKFNGTETLRNIVAQLEAKAEAAedtlILKADDDIDVYADYDRFVQIMVNIIQNAIQ-FTEN 388
Cdd:COG4192 489 K-SLRQFSRKSDT-PLQPVDLRQVIEQAWELVESRAKPQQI----TLHIPDDLMVQGDQVLLEQVLVNLLVNALDaVATQ 562
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1583047749 389 GQIMVTLEKGYLETIITIEDTGIGmseqqmksiWDRYYKVDPSRKNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKG 467
Cdd:COG4192 563 PQISVDLLSNAENLRVAISDNGNG---------WPLVDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLYLASTLERG 632
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
198-242 |
9.29e-12 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 59.77 E-value: 9.29e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1583047749 198 VKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSL 242
Cdd:cd06225 1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
373-475 |
9.88e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 61.26 E-value: 9.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 373 QIMVNIIQNAIQ-----FTENGQIMVTLE---KGYLetIITIEDTGIGMSEQQMKSIWDRYYkvdpsrkNTKYGESGLGL 444
Cdd:cd16920 3 QVLINLVRNGIEamsegGCERRELTIRTSpadDRAV--TISVKDTGPGIAEEVAGQLFDPFY-------TTKSEGLGMGL 73
|
90 100 110
....*....|....*....|....*....|.
gi 1583047749 445 PIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16920 74 SICRSIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
13-482 |
1.19e-11 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 67.06 E-value: 1.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 13 GMVALILLIVGVSFTQLTKQTIEENNYQQLFGYAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDK 92
Cdd:COG2770 56 LLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 93 NERVIYPTNTALLNFTLTTDQWKNLRSGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQPARNIDNSVRpit 172
Cdd:COG2770 136 LALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALL--- 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 173 lNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQ 252
Cdd:COG2770 213 -LLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEE 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 253 ENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNG 332
Cdd:COG2770 292 EELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEA 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 333 TETLRNIVAQLEAKAEAAEDTLILKADDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIMVTLEKGYLETIITIEDTGIG 412
Cdd:COG2770 372 ELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAIAAAAAA 451
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 413 MSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLPDVEIKEE 482
Cdd:COG2770 452 EAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEELAEELLLLEGLLLLLLL 521
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
373-475 |
3.07e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 59.77 E-value: 3.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 373 QIMVNIIQNAIQFTeNGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNtkyGESGLGLPIVQQLVR 452
Cdd:cd16950 3 RVLSNLVDNALRYG-GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARGT---SGTGLGLAIVQRISD 78
|
90 100
....*....|....*....|...
gi 1583047749 453 LHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16950 79 AHGGSLTLANRAGGGLCARIELP 101
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
373-474 |
1.21e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 58.24 E-value: 1.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 373 QIMVNIIQNA---IQFTENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTkygesGLGLPIVQQ 449
Cdd:cd16976 3 QVLMNLLQNAldaMGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPVGKGT-----GLGLSISYG 77
|
90 100
....*....|....*....|....*
gi 1583047749 450 LVRLHKGKLEVESELGKGTKFTVRL 474
Cdd:cd16976 78 IVEEHGGRLSVANEEGAGARFTFDL 102
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
372-475 |
3.11e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 57.41 E-value: 3.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 372 VQIMVNIIQNAIQFT--ENGQIM--------VTL--EKGYLETIITIEDTGIGMSEQQMKSIwdrYYKVDPSRKNTkyge 439
Cdd:cd16918 2 IQVFLNLVRNAAQALagSGGEIIlrtrtqrqVTLghPRHRLALRVSVIDNGPGIPPDLQDTI---FYPMVSGRENG---- 74
|
90 100 110
....*....|....*....|....*....|....*.
gi 1583047749 440 SGLGLPIVQQLVRLHKGKLEVESELGKgTKFTVRLP 475
Cdd:cd16918 75 TGLGLAIAQNIVSQHGGVIECDSQPGH-TVFSVSLP 109
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
198-247 |
4.16e-10 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 55.33 E-value: 4.16e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1583047749 198 VKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKESQA 247
Cdd:smart00304 4 LRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
404-475 |
4.67e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 57.00 E-value: 4.67e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1583047749 404 ITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTkygesGLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16919 50 LEVSDTGSGMPAEVLRRAFEPFFTTKEVGKGT-----GLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
237-475 |
5.86e-10 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 60.87 E-value: 5.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 237 KMTNSLKESQAEIEE-QENRRRQFMADASHEMRTPLTTINGLLEGLEyNAIPENQRENAIKLMKNETERLIRLVNENLDY 315
Cdd:PRK11073 110 PMDNQRRLSQEQLQHaQQVAARDLVRGLAHEIKNPLGGLRGAAQLLS-KALPDPALTEYTKVIIEQADRLRNLVDRLLGP 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 316 EKIRTNQ---ISMVIkkfngtETLRNIVAqLEAkaeaaEDTLILKADDDI---DVYADYDRFVQIMVNIIQNAIQF--TE 387
Cdd:PRK11073 189 QRPGTHVtesIHKVA------ERVVQLVS-LEL-----PDNVRLIRDYDPslpELAHDPDQIEQVLLNIVRNALQAlgPE 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 388 NGQIMVTLEKGYLETI----------ITIEDTGIGMSEQQMKSIwdrYYKVDPSRKntkyGESGLGLPIVQQLVRLHKGK 457
Cdd:PRK11073 257 GGTITLRTRTAFQLTLhgeryrlaarIDIEDNGPGIPPHLQDTL---FYPMVSGRE----GGTGLGLSIARNLIDQHSGK 329
|
250
....*....|....*...
gi 1583047749 458 LEVESELGKgTKFTVRLP 475
Cdd:PRK11073 330 IEFTSWPGH-TEFSVYLP 346
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
377-475 |
9.35e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 55.90 E-value: 9.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 377 NIIQNAIQFTENG-QIMVTLEKGYLetIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKyGESGLGLPIVQQLVRLHK 455
Cdd:cd16939 7 NLLRNALRYAHRTvRIALLVSGGRL--TLIVEDDGPGIPAAARERVFEPFVRLDPSRDRAT-GGFGLGLAIVHRVALWHG 83
|
90 100
....*....|....*....|.
gi 1583047749 456 GKLEV-ESELGkGTKFTVRLP 475
Cdd:cd16939 84 GHVECdDSELG-GACFRLTWP 103
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
377-475 |
9.45e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 55.86 E-value: 9.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 377 NIIQNAIQFT-ENGQIMVT--LEKGYLEtiITIEDTGIGMSEQQMKSIWDRYYKVDPSRkNTkyGESGLGLPIVQQLVRL 453
Cdd:cd16923 7 NLLSNAIKYSpENTRIYITsfLTDDVVN--IMFKNPSSHPLDFKLEKLFERFYRGDNSR-NT--EGAGLGLSIAKAIIEL 81
|
90 100
....*....|....*....|..
gi 1583047749 454 HKGKLEVESElGKGTKFTVRLP 475
Cdd:cd16923 82 HGGSASAEYD-DNHDLFKVRLP 102
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
238-475 |
1.94e-09 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 59.95 E-value: 1.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 238 MTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMkNETERLIRLVNENLDYEK 317
Cdd:PRK10618 432 VNKKLQQAQREYEKNQQARKAFLQNIGDELKQPLQSLAQLAAQLRQTSDEEQQQPELDQLA-EQSDVLVRLVDNIQLLNM 510
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 318 IRTNQISMVIKKFNGTETLRNIVAQLEAKAEAAEDTLI----LKADDDIdvYADYDRFVQIMVNIIQNAIQFTENGQIM- 392
Cdd:PRK10618 511 LETQDWKPEQELFSLQDLIDEVLPEVLPAIKRKGLQLLihnhLKAEQLR--IGDRDALRKILLLLLNYAITTTAYGKITl 588
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 393 -VTLEKGYLETI-ITIEDTGIGMSEQQMKSI---------WDRYYKvdpsrkntkygESGLGLPIVQQLVRLHKGKLEVE 461
Cdd:PRK10618 589 eVDQDESSPDRLtIRILDTGAGVSIKELDNLhfpflnqtqGDRYGK-----------ASGLTFFLCNQLCRKLGGHLTIK 657
|
250
....*....|....
gi 1583047749 462 SELGKGTKFTVRLP 475
Cdd:PRK10618 658 SREGLGTRYSIHLK 671
|
|
| HAMP |
pfam00672 |
HAMP domain; |
193-244 |
1.98e-09 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 53.40 E-value: 1.98e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1583047749 193 FAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKE 244
Cdd:pfam00672 2 LARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
14-269 |
5.61e-09 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 58.49 E-value: 5.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 14 MVALILLIVGVSFTQLTKQTIEENNYQQLFGYAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKN 93
Cdd:COG0840 23 ALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 94 ERVIYPTNTALLNFTLTTDQWKNLRSGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQPARNIDNSVRPITL 173
Cdd:COG0840 103 LALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALA 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 174 NLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQE 253
Cdd:COG0840 183 LLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVGQVRESA 262
|
250
....*....|....*.
gi 1583047749 254 NRrrqfMADASHEMRT 269
Cdd:COG0840 263 EQ----VASASEELAA 274
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
356-474 |
5.61e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 51.48 E-value: 5.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 356 LKADDDIDVYADYDRFVQIMVNIIQNAIQFTeNGQIMVTLEK--GYLEtiITIEDTGIGMSEQQMKSIWDRYYKVDPSRK 433
Cdd:cd16954 23 LDISPELRFPGERNDLMELLGNLLDNACKWC-LEFVEVTARQtdGGLH--LIVDDDGPGVPESQRSKIFQRGQRLDEQRP 99
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1583047749 434 NtkygeSGLGLPIVQQLVRLHKGKLEVE-SELGkGTKFTVRL 474
Cdd:cd16954 100 G-----QGLGLAIAKEIVEQYGGELSLSdSPLG-GARFEVVF 135
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
184-475 |
9.10e-08 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 54.53 E-value: 9.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 184 IVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADA 263
Cdd:COG3920 223 LLVLLAALLRLRAAVLEELERRRRARGLGRLLLLLLLLLLLLRALLLLAAGIRLVITERKRAEEELEASLEEKELLLREL 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 264 SHEMRTPLTTINGLLeGLEYNAIPENQRENAIKLMKNeteRL--IRLVNENLdYEKIRTNQISMvikkfngTETLRNIVA 341
Cdd:COG3920 303 HHRVKNNLQVVSSLL-RLQARRADDPEAREALEESQN---RIqaLALVHELL-YQSEDWEGVDL-------RDYLRELLE 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 342 QLEAKAEAAEDTLILKADDdidVYADYDRFVQI--MVN-IIQNAIQF----TENGQIMVTLEKGYLETIITIEDTGIGMS 414
Cdd:COG3920 371 PLRDSYGGRGIRIELDGPD---VELPADAAVPLglILNeLVTNALKHaflsGEGGRIRVSWRREDGRLRLTVSDNGVGLP 447
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1583047749 415 EQqmksiwdryykVDPSRKntkygeSGLGLPIVQQLVRLHKGKLEVESElgKGTKFTVRLP 475
Cdd:COG3920 448 ED-----------VDPPAR------KGLGLRLIRALVRQLGGTLELDRP--EGTRVRITFP 489
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
373-475 |
2.01e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 49.46 E-value: 2.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 373 QIMVNIIQNAIQFTEN-----GQIMVTLEKGYLETI-ITIEDTGIGMSEQQMKSIWDRYykVDPSRKNTkygesGLGLPI 446
Cdd:cd16944 7 QVLTNILKNAAEAIEGrpsdvGEVRIRVEADQDGRIvLIVCDNGKGFPREMRHRATEPY--VTTRPKGT-----GLGLAI 79
|
90 100
....*....|....*....|....*....
gi 1583047749 447 VQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16944 80 VKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
245-475 |
3.11e-06 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 48.46 E-value: 3.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 245 SQAEIEEQENRRRQFMAD----ASHEmrtpLTTINGLLEGLEYNAIPENQRenaiklMKNETERLIRLVNENLdyEKIRT 320
Cdd:COG4585 43 AARAEEAREEERRRIARElhdgVGQS----LSAIKLQLEAARRLLDADPEA------AREELEEIRELAREAL--AELRR 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 321 ---NQISMVIKKFNGTETLRNIVAQLEAKA------EAAEDTLILKADDDIDVYadydRFVQ-IMVNIIQNAiqftENGQ 390
Cdd:COG4585 111 lvrGLRPPALDDLGLAAALEELAERLLRAAgirvelDVDGDPDRLPPEVELALY----RIVQeALTNALKHA----GATR 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 391 IMVTLEKGYLETIITIEDTGIGMSEQQMKSiwdryykvdpsrkntkygeSGLGLPIVQQLVRLHKGKLEVESELGKGTKF 470
Cdd:COG4585 183 VTVTLEVDDGELTLTVRDDGVGFDPEAAPG-------------------GGLGLRGMRERAEALGGTLTIGSAPGGGTRV 243
|
....*
gi 1583047749 471 TVRLP 475
Cdd:COG4585 244 RATLP 248
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
441-475 |
1.22e-05 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 45.65 E-value: 1.22e-05
10 20 30
....*....|....*....|....*....|....*
gi 1583047749 441 GLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16916 144 GVGMDVVKRSIESLGGTIEVESEPGQGTTFTIRLP 178
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
378-475 |
2.08e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 42.93 E-value: 2.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 378 IIQ----NAIQFTENGQIMVTLEKGYLETIITIEDTGIGmseqqmksiwdryyKVDPSRKntkyGESGLGLPIVQQLVRL 453
Cdd:cd16917 4 IVQealtNALKHAGASRVRVTLSYTADELTLTVVDDGVG--------------FDGPAPP----GGGGFGLLGMRERAEL 65
|
90 100
....*....|....*....|..
gi 1583047749 454 HKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16917 66 LGGTLTIGSRPGGGTRVTARLP 87
|
|
| HATPase_YehU-like |
cd16956 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
378-475 |
7.24e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YehU; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Escherichia coli YehU, a HK of the two-component system (TCS) YehU-YehT which is involved in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase); some have a GAF sensor domain while some have a cupin domain.
Pssm-ID: 340432 [Multi-domain] Cd Length: 101 Bit Score: 41.65 E-value: 7.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 378 IIQNAI-----QFTENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIwdryykvdPSRKNtkygeSGLGLPIVQQLVR 452
Cdd:cd16956 9 IVENAVkhglsGLLDGGRVEITARLDGQHLLLEVEDNGGGMDPDTLARI--------LIRSS-----NGLGLNLVDKRLR 75
|
90 100
....*....|....*....|....*.
gi 1583047749 453 LHKGK---LEVESELGKGTKFTVRLP 475
Cdd:cd16956 76 QAFGNdygLDIECAPGEGTRITIRLP 101
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
441-475 |
1.46e-04 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 44.40 E-value: 1.46e-04
10 20 30
....*....|....*....|....*....|....*
gi 1583047749 441 GLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:COG0643 383 GVGMDVVKTNIEALGGTIEIESEPGKGTTFTLRLP 417
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
367-482 |
2.45e-04 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 43.67 E-value: 2.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 367 DYDRFVQIMVNIIQNAIQFT-----ENGQIMVTLEKGYLETIITIEDTGIGMSEQQMKSIWDRyykvDPSRKNTKYGESG 441
Cdd:PRK15053 429 DSTEFAAIVGNLLDNAFEASlrsdeGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQ----GVSTRADEPGEHG 504
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1583047749 442 LGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLPDVEIKEE 482
Cdd:PRK15053 505 IGLYLIASYVTRCGGVITLEDNDPCGTLFSIFIPKVKPNDS 545
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
360-475 |
2.73e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 40.86 E-value: 2.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 360 DDIDVYADYDRFVQIMVN-IIQNAIQ--FT--ENGQIMVTLEKGYLETIITIEDTGIGMSEQQmksiwdryykvDPSRKN 434
Cdd:cd16951 28 DTGPVSSEVATAIGLVVNeLLQNALKhaFSdrEGGTITIRSVVDGDYLRITVIDDGVGLPQDE-----------DWPNKG 96
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1583047749 435 TkygesgLGLPIVQQLVRLHKGKLEVESELGKGTKFTVRLP 475
Cdd:cd16951 97 S------LGLQIVRSLVEGELKAFLEVQSAENGTRVNIDIP 131
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
374-475 |
2.78e-04 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 40.67 E-value: 2.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 374 IMVNIIQNAIQFTENGQIMVTLE--KGYLEtiITIEDTGIGMseqqmksiwdryykvDPSRKNTKY---GESGLGLPIVQ 448
Cdd:COG2172 42 AVTNAVRHAYGGDPDGPVEVELEldPDGLE--IEVRDEGPGF---------------DPEDLPDPYstlAEGGRGLFLIR 104
|
90 100
....*....|....*....|....*..
gi 1583047749 449 QLVRlhkgKLEVESELGkGTKFTVRLP 475
Cdd:COG2172 105 RLMD----EVEYESDPG-GTTVRLVKR 126
|
|
| PRK10935 |
PRK10935 |
nitrate/nitrite two-component system sensor histidine kinase NarQ; |
180-319 |
3.93e-04 |
|
nitrate/nitrite two-component system sensor histidine kinase NarQ;
Pssm-ID: 236800 [Multi-domain] Cd Length: 565 Bit Score: 42.92 E-value: 3.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 180 IFSSIVAVIASYAFAAFQVKRINR--------LRNATKEVTNGNFD-VQLPVHDKDEFDELADDFNKMTNSLKESQAEIE 250
Cdd:PRK10935 151 AAISLLGLILILTLVFFTVRFTRRqvvaplnqLVTASQQIEKGQFDhIPLDTTLPNELGLLAKAFNQMSSELHKLYRSLE 230
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1583047749 251 E----------QENRRRQFMADASHEMRTPLTTINGLLEGLEYnaipenqrenaikLMKNETERLIRLVNENLDYEKIR 319
Cdd:PRK10935 231 AsveektrkltQANRSLEVLYQCSQALNASQIDVHCFRHILQI-------------VRDHEGLDYLELEVGENEHWRIS 296
|
|
| HATPase_YpdA-YehU-LytS-like |
cd16924 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
378-475 |
4.68e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA, YehU, Bacillus subtilis LytS, and some hybrid sensor histidine kinases; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. It also includes the HATPase domains of Escherichia coli YpdA and YehU, HKs of YpdA-YpdB and YehU-YehTCSs, which are involved together in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), some having accessory sensor domain(s) such as Cache, HAMP or GAF; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340401 [Multi-domain] Cd Length: 103 Bit Score: 39.35 E-value: 4.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1583047749 378 IIQNAIQ-----FTENG--QIMVTLEKGYLEtiITIEDTGIGMSEqqmksiwdryyKVDPSRKNTKYGESGLGLPIVQQL 450
Cdd:cd16924 9 LVENAIQhglspLTDKGvvTISALKEDNHVM--IEVEDNGRGIDP-----------KVLNILGKKPKEGNGIGLYNVHQR 75
|
90 100
....*....|....*....|....*...
gi 1583047749 451 VRLHKGK---LEVESELGKGTKFTVRLP 475
Cdd:cd16924 76 LILLFGEdygIHIASEPDKGTRITFTIP 103
|
|
| |
