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Conserved domains on  [gi|1584997598|ref|WP_131067022|]
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ribonuclease P protein component, partial [Clostridioides difficile]

Protein Classification

ribonuclease P protein component( domain architecture ID 10001764)

ribonuclease P catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus, and can also cleave other RNA substrates such as 4.5S RNA

CATH:  3.30.230.10
EC:  3.1.26.5
Gene Ontology:  GO:0004526|GO:0042781|GO:0000049|GO:0030677|GO:0008033|GO:0001682
PubMed:  12831883|1689306|21076397
SCOP:  4000954

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RnpA COG0594
RNase P protein component [Translation, ribosomal structure and biogenesis];
1-67 6.23e-23

RNase P protein component [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 440359  Cd Length: 99  Bit Score: 83.25  E-value: 6.23e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1584997598  1 SRVGISVSKKVGKAITRNRVRRLIKEAYRLNIDEkIKPGYDIVFIARVSIKDATFKDIDKSIKNLVK 67
Cdd:COG0594   34 PRLGFSVSKKVGNAVVRNRIKRRLREAFRLNKPE-LPPGYDIVVIARPGAAELDFAELEKELEKLLK 99
 
Name Accession Description Interval E-value
RnpA COG0594
RNase P protein component [Translation, ribosomal structure and biogenesis];
1-67 6.23e-23

RNase P protein component [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440359  Cd Length: 99  Bit Score: 83.25  E-value: 6.23e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1584997598  1 SRVGISVSKKVGKAITRNRVRRLIKEAYRLNIDEkIKPGYDIVFIARVSIKDATFKDIDKSIKNLVK 67
Cdd:COG0594   34 PRLGFSVSKKVGNAVVRNRIKRRLREAFRLNKPE-LPPGYDIVVIARPGAAELDFAELEKELEKLLK 99
Ribonuclease_P pfam00825
Ribonuclease P;
1-68 1.82e-20

Ribonuclease P;


Pssm-ID: 425888  Cd Length: 107  Bit Score: 77.23  E-value: 1.82e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1584997598   1 SRVGISVSKKVGKAITRNRVRRLIKEAYRLNIDEkIKPGYDIVFIARVSIKDATFKDIDKSIKNLVKR 68
Cdd:pfam00825  39 PRLGISVSKKVGKAVVRNRIKRLIREAFRLNKDE-LPPGLDIVVIARPGAADADFAELLKELEKLLKK 105
rnpA TIGR00188
ribonuclease P protein component, eubacterial; This peptide is the protein component of a ...
 1-68 1.40e-10

ribonuclease P protein component, eubacterial; This peptide is the protein component of a ribonucleoprotein that cleaves the leader sequence from each tRNA precursor to leave the mature 5'-terminus. The catalytic site is in the RNA component, M1 RNA. The yeast mitochondrial RNase P protein component gene RPM2 has no obvious sequence similarity to rnpA, but resembles eukaryotic nuclear RNase P instead. [Transcription, RNA processing]


Pssm-ID: 211560  Cd Length: 111  Bit Score: 52.32  E-value: 1.40e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1584997598   1 SRVGISVSKK-VGKAITRNRVRRLIKEAYRLNIDEkiKPGYDIVFIARVSIKDATFKDIDKSIKNLVKR 68
Cdd:TIGR00188  40 PRVGLSVSKKkVKNAVERNRIKRLIREVFRERQEE--LKALDVVVIVRKGFSELTYEALLKLLLQLFLR 106
rnpA PRK01903
ribonuclease P protein component;
1-31 9.48e-06

ribonuclease P protein component;


Pssm-ID: 234989  Cd Length: 133  Bit Score: 40.38  E-value: 9.48e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1584997598   1 SRVGISVSKK-VGKAITRNRVRRLIKEAYRLN 31
Cdd:PRK01903   50 ASVLFSVSKKrVPRAVKRNRIKRLMREAYRLE 81
 
Name Accession Description Interval E-value
RnpA COG0594
RNase P protein component [Translation, ribosomal structure and biogenesis];
1-67 6.23e-23

RNase P protein component [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440359  Cd Length: 99  Bit Score: 83.25  E-value: 6.23e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1584997598  1 SRVGISVSKKVGKAITRNRVRRLIKEAYRLNIDEkIKPGYDIVFIARVSIKDATFKDIDKSIKNLVK 67
Cdd:COG0594   34 PRLGFSVSKKVGNAVVRNRIKRRLREAFRLNKPE-LPPGYDIVVIARPGAAELDFAELEKELEKLLK 99
Ribonuclease_P pfam00825
Ribonuclease P;
1-68 1.82e-20

Ribonuclease P;


Pssm-ID: 425888  Cd Length: 107  Bit Score: 77.23  E-value: 1.82e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1584997598   1 SRVGISVSKKVGKAITRNRVRRLIKEAYRLNIDEkIKPGYDIVFIARVSIKDATFKDIDKSIKNLVKR 68
Cdd:pfam00825  39 PRLGISVSKKVGKAVVRNRIKRLIREAFRLNKDE-LPPGLDIVVIARPGAADADFAELLKELEKLLKK 105
rnpA TIGR00188
ribonuclease P protein component, eubacterial; This peptide is the protein component of a ...
 1-68 1.40e-10

ribonuclease P protein component, eubacterial; This peptide is the protein component of a ribonucleoprotein that cleaves the leader sequence from each tRNA precursor to leave the mature 5'-terminus. The catalytic site is in the RNA component, M1 RNA. The yeast mitochondrial RNase P protein component gene RPM2 has no obvious sequence similarity to rnpA, but resembles eukaryotic nuclear RNase P instead. [Transcription, RNA processing]


Pssm-ID: 211560  Cd Length: 111  Bit Score: 52.32  E-value: 1.40e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1584997598   1 SRVGISVSKK-VGKAITRNRVRRLIKEAYRLNIDEkiKPGYDIVFIARVSIKDATFKDIDKSIKNLVKR 68
Cdd:TIGR00188  40 PRVGLSVSKKkVKNAVERNRIKRLIREVFRERQEE--LKALDVVVIVRKGFSELTYEALLKLLLQLFLR 106
rnpA PRK01903
ribonuclease P protein component;
1-31 9.48e-06

ribonuclease P protein component;


Pssm-ID: 234989  Cd Length: 133  Bit Score: 40.38  E-value: 9.48e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1584997598   1 SRVGISVSKK-VGKAITRNRVRRLIKEAYRLN 31
Cdd:PRK01903   50 ASVLFSVSKKrVPRAVKRNRIKRLMREAYRLE 81
rnpA PRK03459
ribonuclease P; Reviewed
 2-63 1.87e-03

ribonuclease P; Reviewed


Pssm-ID: 235126  Cd Length: 122  Bit Score: 34.00  E-value: 1.87e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1584997598   2 RVGISVSKKVGKAITRNRVRRLIKEAYrLNIDEKIKPGYDIVFIARVSIKDATFKDIDKSIK 63
Cdd:PRK03459   49 RFGLVVSKAVGNAVIRHRVSRRLRHIC-ADIVDQVPETHHVVIRALPGAATASSAELERDVR 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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