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Conserved domains on  [gi|1601809800|ref|WP_134198262|]
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TonB-dependent receptor [Meridianimaribacter flavus]

Protein Classification

TonB-dependent receptor( domain architecture ID 13843999)

TonB dependent receptor having a carboxypeptidase regulatory-like domain, may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0016020
PubMed:  16980464

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TonB-Xanth-Caul super family cl36973
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 105-942 1.05e-165

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


The actual alignment was detected with superfamily member TIGR01782:

Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 505.72  E-value: 1.05e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 105 LDEVEVVAYGfGSQARALNTQKNKTNITNIVSTDQIGKFPDANIGDAVKRIPGITMQVDQGEARNIIVRGLSPQLNSVTL 184
Cdd:TIGR01782   1 LDAVQVTGQR-ASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 185 NGSRIPSAEGDNRNVQMDLIPSDMIQTIEVNKAVTPDMDGDALGGSVNLITkTSP---QGFRLSATAGSGINFITDKRIL 261
Cdd:TIGR01782  80 NGRTIASTDSGGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRT-RSPfdyDGRTLSGSAQGGYNDLAGKDKP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 262 NGSFLVGDRSKN--NKFGWMVSASINDNDFGSDNVEAEWTDEFEFNNGDEDNLeevdvnPYANVFEIREYLVQRVRRSFS 339
Cdd:TIGR01782 159 GPRGAASYSWTFgdGQFGVLLSASYQKRDFAEDNVETENWGTYTSADGGAQGL------YFPRGVRYRSYRNDRERKGVN 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 340 ANLDYKLDKNNTVYFKSIYNWRDDRENRFRLEHEILDGEDIGAGDFSVDANGNLTMFPVEAKRqskGGIDSKRNKnarlE 419
Cdd:TIGR01782 233 GSLQWRPSDALELYLDTLYSKYDDDETRQQIEFRTLNGGSTVITSNQTATSGALVQGTVANLQ---ILVEARYNE----E 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 420 DQRMQNYSLGGEHLFGKVQMDWMASFSKASEERLN---ERYLEYESEYAVNFNNNQDKPLFSPVSATDANY----EDFEF 492
Cdd:TIGR01782 306 KETTTSLTLGGEWTGDRWTLDGDLGYSKATRDRPDrvtRFFTAPTPGYDFDYRGGPTLTLGTPADGDDASNytnpANGEL 385

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 493 GELTEENQYTEEKDFNLFVNAQvpmsvVNGRDGFLKFGAK-TRLKNKNRENDFT-EYGDETGALEFLGMVP---TRNYSD 567
Cdd:TIGR01782 386 RRTQISYQKAEDSEDAAQLDAT-----FDGPFTSLKFGVRyRRRDKTNRGSRYRrSIIGATGASGLAGVPSdlaGAGLDG 460

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 568 SDFLAGGQYQVG------NFASPEFLGGLNlndsnlfeaeNLPEEYITANFDVNENVYAGYAMLNQDLSDKLSVLAGVRL 641
Cdd:TIGR01782 461 GLGGPLTGWDPAdldaflNAARGDAAGGGT----------YTYASTAPNTYTVTEDTTAAYAMANFDTGLRLRGNVGVRY 530

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 642 EHTSIESEGNELEFDTEGDVSGINVVKDKNSYTNILPGVHFKYNLNDNTILRFAWTNTLARPNYVDLVPYREIN----NE 717
Cdd:TIGR01782 531 ERTDQTSDGWQSQPAANGTGSVLVPVSADRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFGDLAANTSLSddgtGG 610

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 718 DEEIFLGNSELDPTTSMNFDVMAEHYFKSVGIISGGLFYKDIQDFVYTFQS---------ENEDGFEVYQPLNGDDA-SV 787
Cdd:TIGR01782 611 TVTVSGGNPDLKPYESDNLDLSLEWYFGPGGLLSAAVFYKDIKNFIVTTTStetndggggLVVAGVLVSRPVNGGKAgKI 690

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 788 FGAEVSFQRRLDFLPGFAKNFSVYLNYTYLTSSTDGIrnEDGEERTDLDLPQTAPNMFNGSLGYAGKNFSLRLSANYSDA 867
Cdd:TIGR01782 691 RGVELGYQQTFDFLPGPLSGFGVQANYTYVDSEADPS--VDGVQRRKLPLPGLSKNTANATLYYEKGGFSARLSYNYRSD 768

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1601809800 868 YIDEIGG--NAFEDRYYDEQLFLDFNANVAINKNLSLYLNINNITNQPLRYYQGVSSRTMQMEYYEKRLTFGLKYDL 942
Cdd:TIGR01782 769 YLLDVGGsnINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYKF 845
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
 24-110 1.46e-19

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


:

Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 84.18  E-value: 1.46e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  24 LQGIITDDN-GITVPGATVMIEELKKAVVSDFDGKFTMVDIPEGTYNLLIKYLGYADFKQEVTVTASQTTELNITLTSKS 102
Cdd:pfam13715   1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKNLPAGTYTLVVSFVGYKTQEKKVTVSNDNTLDVNFLLKEDA 80


                  ....*...
gi 1601809800 103 TELDEVEV 110
Cdd:pfam13715  81 LLLDEVVV 88
 
Name Accession Description Interval E-value
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 105-942 1.05e-165

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 505.72  E-value: 1.05e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 105 LDEVEVVAYGfGSQARALNTQKNKTNITNIVSTDQIGKFPDANIGDAVKRIPGITMQVDQGEARNIIVRGLSPQLNSVTL 184
Cdd:TIGR01782   1 LDAVQVTGQR-ASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 185 NGSRIPSAEGDNRNVQMDLIPSDMIQTIEVNKAVTPDMDGDALGGSVNLITkTSP---QGFRLSATAGSGINFITDKRIL 261
Cdd:TIGR01782  80 NGRTIASTDSGGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRT-RSPfdyDGRTLSGSAQGGYNDLAGKDKP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 262 NGSFLVGDRSKN--NKFGWMVSASINDNDFGSDNVEAEWTDEFEFNNGDEDNLeevdvnPYANVFEIREYLVQRVRRSFS 339
Cdd:TIGR01782 159 GPRGAASYSWTFgdGQFGVLLSASYQKRDFAEDNVETENWGTYTSADGGAQGL------YFPRGVRYRSYRNDRERKGVN 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 340 ANLDYKLDKNNTVYFKSIYNWRDDRENRFRLEHEILDGEDIGAGDFSVDANGNLTMFPVEAKRqskGGIDSKRNKnarlE 419
Cdd:TIGR01782 233 GSLQWRPSDALELYLDTLYSKYDDDETRQQIEFRTLNGGSTVITSNQTATSGALVQGTVANLQ---ILVEARYNE----E 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 420 DQRMQNYSLGGEHLFGKVQMDWMASFSKASEERLN---ERYLEYESEYAVNFNNNQDKPLFSPVSATDANY----EDFEF 492
Cdd:TIGR01782 306 KETTTSLTLGGEWTGDRWTLDGDLGYSKATRDRPDrvtRFFTAPTPGYDFDYRGGPTLTLGTPADGDDASNytnpANGEL 385

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 493 GELTEENQYTEEKDFNLFVNAQvpmsvVNGRDGFLKFGAK-TRLKNKNRENDFT-EYGDETGALEFLGMVP---TRNYSD 567
Cdd:TIGR01782 386 RRTQISYQKAEDSEDAAQLDAT-----FDGPFTSLKFGVRyRRRDKTNRGSRYRrSIIGATGASGLAGVPSdlaGAGLDG 460

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 568 SDFLAGGQYQVG------NFASPEFLGGLNlndsnlfeaeNLPEEYITANFDVNENVYAGYAMLNQDLSDKLSVLAGVRL 641
Cdd:TIGR01782 461 GLGGPLTGWDPAdldaflNAARGDAAGGGT----------YTYASTAPNTYTVTEDTTAAYAMANFDTGLRLRGNVGVRY 530

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 642 EHTSIESEGNELEFDTEGDVSGINVVKDKNSYTNILPGVHFKYNLNDNTILRFAWTNTLARPNYVDLVPYREIN----NE 717
Cdd:TIGR01782 531 ERTDQTSDGWQSQPAANGTGSVLVPVSADRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFGDLAANTSLSddgtGG 610

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 718 DEEIFLGNSELDPTTSMNFDVMAEHYFKSVGIISGGLFYKDIQDFVYTFQS---------ENEDGFEVYQPLNGDDA-SV 787
Cdd:TIGR01782 611 TVTVSGGNPDLKPYESDNLDLSLEWYFGPGGLLSAAVFYKDIKNFIVTTTStetndggggLVVAGVLVSRPVNGGKAgKI 690

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 788 FGAEVSFQRRLDFLPGFAKNFSVYLNYTYLTSSTDGIrnEDGEERTDLDLPQTAPNMFNGSLGYAGKNFSLRLSANYSDA 867
Cdd:TIGR01782 691 RGVELGYQQTFDFLPGPLSGFGVQANYTYVDSEADPS--VDGVQRRKLPLPGLSKNTANATLYYEKGGFSARLSYNYRSD 768

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1601809800 868 YIDEIGG--NAFEDRYYDEQLFLDFNANVAINKNLSLYLNINNITNQPLRYYQGVSSRTMQMEYYEKRLTFGLKYDL 942
Cdd:TIGR01782 769 YLLDVGGsnINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYKF 845
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 134-941 6.33e-60

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 216.55  E-value: 6.33e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 134 IVSTDQIGKFPDANIGDAVKRIPGITMQVDQ-GEARNIIVRGLSPQLNSVTLNGSRIPSAeGDNRNVQMDLIPSDMIQTI 212
Cdd:cd01347     4 VITAEDIEKQPATSLADLLRRIPGVSVTRGGgGGGSTISIRGFGPDRTLVLVDGLPLASS-NYGRGVDLNTIPPELIERV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 213 EVNKAVTPDM-DGDALGGSVNLITKTSPQGFRLSATAGSGINFITDKRilNGSFLVGDR-SKNNKFGWMVSASINDND-F 289
Cdd:cd01347    83 EVLKGPSSALyGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSG--GGGFDVSGAlADDGAFGARLYGAYRDGDgT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 290 GSDNVEAEWTDefefnngdednleevdvnpyanvfeireylvqRVRRSFSANLDYKLDKNNTVYFKSIYNWRDDRENRfr 369
Cdd:cd01347   161 IDGDGQADDSD--------------------------------EERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPG-- 206

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 370 leHEILDGEDIGAGDFSVDANGNLtmfpveakrqskggidskrNKNARLEDQRMQNYSLGGEHLFGkvqmDWMASFskas 449
Cdd:cd01347   207 --GTLPANGTGSSLGGGPSSNTNG-------------------DRDWDYRDRYRKRASLGLEHDLN----DTGWTL---- 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 450 eeRLNERYLEyeseyavNFNNNQDKPLFSPVSATDANYEDFEFGELTEENQYTEEKDFNLfvnaqvpmsvvngrdgflKF 529
Cdd:cd01347   258 --RANLSYSY-------TDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLNA------------------PF 310

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 530 GAKTRLKNknrendfteygdetgaleflgmvptrnysdsdFLAGGQYQvgnfaspeflgglnlndsnlfeaenlpeeyit 609
Cdd:cd01347   311 GTGPVAHT--------------------------------LTLGVEYR-------------------------------- 326

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 610 aNFDVNENVYAGYAMLNQDLSDKLSVLAGVRLEHTSIESEGNelefdtegdvsGINVVKDKNSYTNILPGVHFKYNLNDN 689
Cdd:cd01347   327 -REELDEKQTALYAQDTIELTDDLTLTLGLRYDHYDQDSKDT-----------IAGGTTAKKSYSHWSPSLGLVYKLTDG 394

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 690 TILRFAWTNTLARPNYVDLVPYREINNedeEIFLGNSELDPTTSMNFDVMAEHYFKSVGIISGGLFYKDIQDFVYTfQSE 769
Cdd:cd01347   395 LSLYASYSQGFRAPSLGELYGGGSHGG---TAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVS-TPT 470

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 770 NEDGFEVYQPLNGDDASVFGAEVSFQRRldflpgFAKNFSVYLNYTYltssTDGIRNEDGEERTDLDLPQTAPNMFNGSL 849
Cdd:cd01347   471 NTGLGLVTVYVNGGKARIRGVELEASYD------LTDGLGLTGSYTY----TDTEVKRTDGATTGNRLPGIPKHTANLGL 540

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 850 GY--AGKNFSLRLSANYSDA-YIDEIGGNafEDRYYDEQLFLDFNANVAINKNLSLYLNINNITNQplRYYQGVSSRTMQ 926
Cdd:cd01347   541 DYelPDEGLTAGGGVRYRGKqYADTANGN--NTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDK--DYYTSLSVRGSG 616

                         810
                  ....*....|....*...
gi 1601809800 927 MEYYEKR---LTFGLKYD 941
Cdd:cd01347   617 LYGYYGPgrtYYLSVSYK 634
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 84-903 7.43e-50

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 186.99  E-value: 7.43e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  84 VTVTASQTTELNITLTSKSTELDEVEVVAYGFGSQARalntqkNKTNITNIVSTDQIGKFPDANIGDAVKRIPGITMQVD 163
Cdd:COG4771     6 LLLLLALAAQAADALAEDATELEEVVVTATRTEQSLS------DAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 164 QG--EARNIIVRGLSPQLNSVTLNGSRIPSAEGDNRnVQMDLIPSDMIQTIEVNKAVTPDMDG-DALGGSVNLITKTSPQ 240
Cdd:COG4771    80 GGrgGSSGISIRGLGGDRVLVLIDGVPVNNPALGGG-GDLSYIPPDDIERIEVIRGPASALYGsDAIGGVINIITKKPTD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 241 GFRLSATAGSGINfitDKRILNGSFLVGdrSKNNKFGWMVSASINDNDFGSDNVEAEWTDEFEFNngdednleevdvnpy 320
Cdd:COG4771   159 ELEGSVSLGYGSN---GNGTYSGSLSLG--GPGDKLSFLLSGSYRDRDGYLDYRNGGFVGNSGYE--------------- 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 321 anvfeireylvqrvRRSFSANLDYKLDKNNTVYFKSIYNWRDDRENRFRLEHEILDGEDIGAGDFSVDangnltmfpvea 400
Cdd:COG4771   219 --------------RYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTD------------ 272

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 401 krqskggidskrnknarledqrMQNYSLGGEHLFGKvqmDWMASFSkaseerlneryleyeseyavnFNNNQDKPLFSPV 480
Cdd:COG4771   273 ----------------------RGNYSLRYNGDLGD---NLDLSLY---------------------YSRTDRDSTNGSL 306

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 481 SATDANYEDfefgelTEENQYTEEKDFNLFVNaqvpmsvvngrdgflkfgaktrlknknrendfteygdetgaleflgmv 560
Cdd:COG4771   307 GGSTGSFSD------SDDTTYGLELDLTYPLG------------------------------------------------ 332

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 561 ptrnySDSDFLAGGQYQVgnfaspeflgglnlndsnlfeaENLPEEYITANFDVNENVYAGYAMLNQDLSDKLSVLAGVR 640
Cdd:COG4771   333 -----GNHTLTLGAEYRY----------------------DDLDSSSFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLR 385

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 641 LEHTSIEsegnelefdtegdvsginvvkDKNSYTNILPGVHFKYNLNDNTILRFAWTNTLARPNYVDLvpYREINNEDEE 720
Cdd:COG4771   386 YDYYSTF---------------------GASNYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAEL--YGSGTGTPGR 442

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 721 IFLGNSELDPTTSMNFDVMAEHYFKSVGI-ISGGLFYKDIQDFVYTFQSENEDGFeVYQPLNGDDASVFGAEVSFQRRLD 799
Cdd:COG4771   443 YVLGNPDLKPETSDNYELGLEYRLGNGGLsLSLTGFYTDIKDLIVLVPVGPGPGD-VLQYENVGKARTYGLELELKYRLG 521

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 800 flpgfaKNFSVYLNYTYLTSstdgiRNEDGEerTDLDLPQTAPNMFNGSLGY-AGKNFSLRLSANYSDAYIDEIGGNAFE 878
Cdd:COG4771   522 ------KGLTLTASYTYLDS-----KIDDGD--TGEPLPNVPPHKANLGLDYrLPKWWLLLLLTRYYGGRYVTPPSGRLE 588

                         810       820
                  ....*....|....*....|....*
gi 1601809800 879 DrYYDEQLFLDFNANVAINKNLSLY 903
Cdd:COG4771   589 G-YTPGYTLLDLRASYKLTKNLTLS 612
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 464-941 8.93e-30

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 124.11  E-value: 8.93e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 464 YAVNFNNNQDKPLFSPVSATDANYEDFEFGELTEENQYTEEKDFNLFVNAQVPMSVVNGRDGFLKFGAKTRLKNKNREND 543
Cdd:pfam00593  34 LDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 544 FTEYGDETGALEFLGMVPTRNYSDSDFLAGGQYQVGNFASPEFLGGLNLNDSNlfeaenlpeeyitaNFDVNENVYAGYA 623
Cdd:pfam00593 114 YGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSS--------------YSDTTTDSYGLYL 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 624 MLNQDLSDKLSVLAGVRLEHtsiesegneleFDTEGDVSGINVVKDKNSYTNILPGVHFKYNLNDNTILRFAWTNTLARP 703
Cdd:pfam00593 180 QDNIKLTDRLTLTLGLRYDH-----------YSTDGDDGNGGGDNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAP 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 704 NYVDLVPYReINNEDEEIFLGNSELDPTTSMNFDVMAEhYFKSVGIISGGLFYKDIQDFVYTFQSENEDGFEVYQPLNGD 783
Cdd:pfam00593 249 SLGELYGSG-SGGGGGAVAGGNPDLKPETSDNYELGLK-YDDGRLSLSLALFYIDIKNLITSDPDGPGLGGTVYTYTNVG 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 784 DASVFGAEVSFQRRLdFLPGFAKNfsvylNYTYLTSSTDGIRNEDGEertdlDLPQTAPNMFNGSLGY--AGKNFSLRLS 861
Cdd:pfam00593 327 KARIRGVELELSGRL-WGLGLSGG-----GYTYTDADDDADADDTGN-----PLPNVPRHTANLGLTYdfPLGGWGARLG 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 862 ANYSDAYiDEIGGNAFEDRYYDEQLFLDFNANVAINKNLSLYLNINNITNQPLRYYQGVSSRTMQMEYYEKR-LTFGLKY 940
Cdd:pfam00593 396 ARYVGSG-ERRYGDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNLGGYPGPGRtFYLGLSY 474


                  .
gi 1601809800 941 D 941
Cdd:pfam00593 475 K 475
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
 24-110 1.46e-19

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 84.18  E-value: 1.46e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  24 LQGIITDDN-GITVPGATVMIEELKKAVVSDFDGKFTMVDIPEGTYNLLIKYLGYADFKQEVTVTASQTTELNITLTSKS 102
Cdd:pfam13715   1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKNLPAGTYTLVVSFVGYKTQEKKVTVSNDNTLDVNFLLKEDA 80


                  ....*...
gi 1601809800 103 TELDEVEV 110
Cdd:pfam13715  81 LLLDEVVV 88
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
96-912 2.17e-09

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 61.18  E-value: 2.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  96 ITLTSKSTELDEVE---VVAYGFGSQaralntQKNKTNITNIVSTDQIGKFPDANIGDAVKRIPGITMQvDQGEARNIIV 172
Cdd:PRK13484   18 VISSGYASSDKKEDtlvVTASGFTQQ------LRNAPASVSVITSEQLQKKPVSDLVDAVKDVEGISIT-GGNEKPDISI 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 173 RGLSPQLNSVTLNGSRIPSAEG---DNRNVQMDLI-PSDMIQTIEVNKAVTPDMDG-DALGGSVNLITK-TSPQGFRLSA 246
Cdd:PRK13484   91 RGLSGDYTLILVDGRRQSGRESrpnGSGGFEAGFIpPVEAIERIEVIRGPMSSLYGsDAIGGVINIITKpVNNQTWDGVL 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 247 TAGSGINFitdkrilNGSFlvGDrSKNNKF---GWMVSASINDNDFGSDNVEAEwtDEFEFNNGDEDNleevdvnpyanv 323
Cdd:PRK13484  171 GLGGIIQE-------HGKF--GN-STTNDFylsGPLIKDKLGLQLYGGMNYRKE--DSISQGTPAKDN------------ 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 324 feireylvqrvrRSFSANLDYKLDKNNTVYFKSiynwrddreNRFRLEHEILDGEDIGAgdfsvdangnLTMfpveakrq 403
Cdd:PRK13484  227 ------------KNITATLQFTPTESQKFVFEY---------GKNNQVHTLTPGESLDA----------WTM-------- 267

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 404 sKGGidsKRNKNARLEDQRMQNYslggehlfgkvqmdWMASFskaseerlneryleyeseyavnfnNNQDKPLFSPVSAt 483
Cdd:PRK13484  268 -RGN---LKQPNSKRETHNSRSH--------------WVAAW------------------------NAQGEILHPEIAV- 304

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 484 danyedfeFGELTEENQYTEEKDfnlfvnaqvpmsVVNGRDgflkfgaktrLKNKNRENDFTEYGDETGALEFLgmvptr 563
Cdd:PRK13484  305 --------YQEKVIREVKSGKKD------------KYNHWD----------LNYESRKPEITNTIIDAKVTAFL------ 348

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 564 nySDSDFLAGGQYQVGNFASPEFLGGLNLNDSNLFEAENlpeeyitANFDVNEnvyagYAMlnqdlSDKLSVLAGVRLEH 643
Cdd:PRK13484  349 --PENVLTIGGQFQHAELRDDSATGKKTTETQSVSIKQK-------AVFIENE-----YAA-----TDSLALTGGLRLDN 409

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 644 TSIesegnelefdtegdvsginvvkdKNSYTNilPGVHFKYNLNDNTILRFAWTNTLARPNYVDLVP-YREINNEDEEIF 722
Cdd:PRK13484  410 HEI-----------------------YGSYWN--PRLYAVYNLTDNLTLKGGIAKAFRAPSIREVSPgFGTLTQGGASIM 464

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 723 LGNSELDPTTSMNFDVMAEHYFKSVGIISGGLFYKDIQDFVYTFQSENED---GFEVYQPLNGDDASVFGAEVSFQrrld 799
Cdd:PRK13484  465 YGNRDLKPETSVTEEIGIIYSNDSGFSASATLFNTDFKNKLTSYDIGTKDpvtGLNTFIYDNVGEANIRGVELATQ---- 540

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 800 fLPgFAKNFSVYLNYTYltssTDGIRNED-----GEERTDLDLPQTAPNMFNGSLGYA-GKNFSLRLSANYSDAYIDEIG 873
Cdd:PRK13484  541 -IP-VYDKWHVSANYTF----TDSRRKSDdeslnGKSLKGEPLERTPRHAANAKLEWDyTQDITFYSSLNYTGKQIWAAQ 614

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|
gi 1601809800 874 GNAFE-DRYYDEQLFLDFNANVAINKNLSLYLNINNITNQ 912
Cdd:PRK13484  615 RNGAKvPRVRNGFTSMDIGLNYQILPDTLINFAVLNVTDR 654
Peptidase_M14NE-CP-C_like cd11308
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, ...
 26-98 6.48e-08

Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.


Pssm-ID: 200604 [Multi-domain]  Cd Length: 76  Bit Score: 50.60  E-value: 6.48e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1601809800  26 GIITDDNGITVPGATVMIEELKKAVVSDFDGKFTMVDIPeGTYNLLIKYLGYADFKQEVTVTAS-QTTELNITL 98
Cdd:cd11308     4 GFVTDATGNPIANATISVEGINHDVTTAKDGDYWRLLLP-GTYNVTASAPGYQPVTKTVTVPNNfSATVVNFTL 76
 
Name Accession Description Interval E-value
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 105-942 1.05e-165

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 505.72  E-value: 1.05e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 105 LDEVEVVAYGfGSQARALNTQKNKTNITNIVSTDQIGKFPDANIGDAVKRIPGITMQVDQGEARNIIVRGLSPQLNSVTL 184
Cdd:TIGR01782   1 LDAVQVTGQR-ASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 185 NGSRIPSAEGDNRNVQMDLIPSDMIQTIEVNKAVTPDMDGDALGGSVNLITkTSP---QGFRLSATAGSGINFITDKRIL 261
Cdd:TIGR01782  80 NGRTIASTDSGGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRT-RSPfdyDGRTLSGSAQGGYNDLAGKDKP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 262 NGSFLVGDRSKN--NKFGWMVSASINDNDFGSDNVEAEWTDEFEFNNGDEDNLeevdvnPYANVFEIREYLVQRVRRSFS 339
Cdd:TIGR01782 159 GPRGAASYSWTFgdGQFGVLLSASYQKRDFAEDNVETENWGTYTSADGGAQGL------YFPRGVRYRSYRNDRERKGVN 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 340 ANLDYKLDKNNTVYFKSIYNWRDDRENRFRLEHEILDGEDIGAGDFSVDANGNLTMFPVEAKRqskGGIDSKRNKnarlE 419
Cdd:TIGR01782 233 GSLQWRPSDALELYLDTLYSKYDDDETRQQIEFRTLNGGSTVITSNQTATSGALVQGTVANLQ---ILVEARYNE----E 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 420 DQRMQNYSLGGEHLFGKVQMDWMASFSKASEERLN---ERYLEYESEYAVNFNNNQDKPLFSPVSATDANY----EDFEF 492
Cdd:TIGR01782 306 KETTTSLTLGGEWTGDRWTLDGDLGYSKATRDRPDrvtRFFTAPTPGYDFDYRGGPTLTLGTPADGDDASNytnpANGEL 385

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 493 GELTEENQYTEEKDFNLFVNAQvpmsvVNGRDGFLKFGAK-TRLKNKNRENDFT-EYGDETGALEFLGMVP---TRNYSD 567
Cdd:TIGR01782 386 RRTQISYQKAEDSEDAAQLDAT-----FDGPFTSLKFGVRyRRRDKTNRGSRYRrSIIGATGASGLAGVPSdlaGAGLDG 460

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 568 SDFLAGGQYQVG------NFASPEFLGGLNlndsnlfeaeNLPEEYITANFDVNENVYAGYAMLNQDLSDKLSVLAGVRL 641
Cdd:TIGR01782 461 GLGGPLTGWDPAdldaflNAARGDAAGGGT----------YTYASTAPNTYTVTEDTTAAYAMANFDTGLRLRGNVGVRY 530

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 642 EHTSIESEGNELEFDTEGDVSGINVVKDKNSYTNILPGVHFKYNLNDNTILRFAWTNTLARPNYVDLVPYREIN----NE 717
Cdd:TIGR01782 531 ERTDQTSDGWQSQPAANGTGSVLVPVSADRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFGDLAANTSLSddgtGG 610

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 718 DEEIFLGNSELDPTTSMNFDVMAEHYFKSVGIISGGLFYKDIQDFVYTFQS---------ENEDGFEVYQPLNGDDA-SV 787
Cdd:TIGR01782 611 TVTVSGGNPDLKPYESDNLDLSLEWYFGPGGLLSAAVFYKDIKNFIVTTTStetndggggLVVAGVLVSRPVNGGKAgKI 690

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 788 FGAEVSFQRRLDFLPGFAKNFSVYLNYTYLTSSTDGIrnEDGEERTDLDLPQTAPNMFNGSLGYAGKNFSLRLSANYSDA 867
Cdd:TIGR01782 691 RGVELGYQQTFDFLPGPLSGFGVQANYTYVDSEADPS--VDGVQRRKLPLPGLSKNTANATLYYEKGGFSARLSYNYRSD 768

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1601809800 868 YIDEIGG--NAFEDRYYDEQLFLDFNANVAINKNLSLYLNINNITNQPLRYYQGVSSRTMQMEYYEKRLTFGLKYDL 942
Cdd:TIGR01782 769 YLLDVGGsnINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYKF 845
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 134-941 6.33e-60

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 216.55  E-value: 6.33e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 134 IVSTDQIGKFPDANIGDAVKRIPGITMQVDQ-GEARNIIVRGLSPQLNSVTLNGSRIPSAeGDNRNVQMDLIPSDMIQTI 212
Cdd:cd01347     4 VITAEDIEKQPATSLADLLRRIPGVSVTRGGgGGGSTISIRGFGPDRTLVLVDGLPLASS-NYGRGVDLNTIPPELIERV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 213 EVNKAVTPDM-DGDALGGSVNLITKTSPQGFRLSATAGSGINFITDKRilNGSFLVGDR-SKNNKFGWMVSASINDND-F 289
Cdd:cd01347    83 EVLKGPSSALyGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSG--GGGFDVSGAlADDGAFGARLYGAYRDGDgT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 290 GSDNVEAEWTDefefnngdednleevdvnpyanvfeireylvqRVRRSFSANLDYKLDKNNTVYFKSIYNWRDDRENRfr 369
Cdd:cd01347   161 IDGDGQADDSD--------------------------------EERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPG-- 206

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 370 leHEILDGEDIGAGDFSVDANGNLtmfpveakrqskggidskrNKNARLEDQRMQNYSLGGEHLFGkvqmDWMASFskas 449
Cdd:cd01347   207 --GTLPANGTGSSLGGGPSSNTNG-------------------DRDWDYRDRYRKRASLGLEHDLN----DTGWTL---- 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 450 eeRLNERYLEyeseyavNFNNNQDKPLFSPVSATDANYEDFEFGELTEENQYTEEKDFNLfvnaqvpmsvvngrdgflKF 529
Cdd:cd01347   258 --RANLSYSY-------TDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLNA------------------PF 310

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 530 GAKTRLKNknrendfteygdetgaleflgmvptrnysdsdFLAGGQYQvgnfaspeflgglnlndsnlfeaenlpeeyit 609
Cdd:cd01347   311 GTGPVAHT--------------------------------LTLGVEYR-------------------------------- 326

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 610 aNFDVNENVYAGYAMLNQDLSDKLSVLAGVRLEHTSIESEGNelefdtegdvsGINVVKDKNSYTNILPGVHFKYNLNDN 689
Cdd:cd01347   327 -REELDEKQTALYAQDTIELTDDLTLTLGLRYDHYDQDSKDT-----------IAGGTTAKKSYSHWSPSLGLVYKLTDG 394

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 690 TILRFAWTNTLARPNYVDLVPYREINNedeEIFLGNSELDPTTSMNFDVMAEHYFKSVGIISGGLFYKDIQDFVYTfQSE 769
Cdd:cd01347   395 LSLYASYSQGFRAPSLGELYGGGSHGG---TAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVS-TPT 470

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 770 NEDGFEVYQPLNGDDASVFGAEVSFQRRldflpgFAKNFSVYLNYTYltssTDGIRNEDGEERTDLDLPQTAPNMFNGSL 849
Cdd:cd01347   471 NTGLGLVTVYVNGGKARIRGVELEASYD------LTDGLGLTGSYTY----TDTEVKRTDGATTGNRLPGIPKHTANLGL 540

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 850 GY--AGKNFSLRLSANYSDA-YIDEIGGNafEDRYYDEQLFLDFNANVAINKNLSLYLNINNITNQplRYYQGVSSRTMQ 926
Cdd:cd01347   541 DYelPDEGLTAGGGVRYRGKqYADTANGN--NTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDK--DYYTSLSVRGSG 616

                         810
                  ....*....|....*...
gi 1601809800 927 MEYYEKR---LTFGLKYD 941
Cdd:cd01347   617 LYGYYGPgrtYYLSVSYK 634
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 84-903 7.43e-50

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 186.99  E-value: 7.43e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  84 VTVTASQTTELNITLTSKSTELDEVEVVAYGFGSQARalntqkNKTNITNIVSTDQIGKFPDANIGDAVKRIPGITMQVD 163
Cdd:COG4771     6 LLLLLALAAQAADALAEDATELEEVVVTATRTEQSLS------DAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 164 QG--EARNIIVRGLSPQLNSVTLNGSRIPSAEGDNRnVQMDLIPSDMIQTIEVNKAVTPDMDG-DALGGSVNLITKTSPQ 240
Cdd:COG4771    80 GGrgGSSGISIRGLGGDRVLVLIDGVPVNNPALGGG-GDLSYIPPDDIERIEVIRGPASALYGsDAIGGVINIITKKPTD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 241 GFRLSATAGSGINfitDKRILNGSFLVGdrSKNNKFGWMVSASINDNDFGSDNVEAEWTDEFEFNngdednleevdvnpy 320
Cdd:COG4771   159 ELEGSVSLGYGSN---GNGTYSGSLSLG--GPGDKLSFLLSGSYRDRDGYLDYRNGGFVGNSGYE--------------- 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 321 anvfeireylvqrvRRSFSANLDYKLDKNNTVYFKSIYNWRDDRENRFRLEHEILDGEDIGAGDFSVDangnltmfpvea 400
Cdd:COG4771   219 --------------RYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTD------------ 272

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 401 krqskggidskrnknarledqrMQNYSLGGEHLFGKvqmDWMASFSkaseerlneryleyeseyavnFNNNQDKPLFSPV 480
Cdd:COG4771   273 ----------------------RGNYSLRYNGDLGD---NLDLSLY---------------------YSRTDRDSTNGSL 306

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 481 SATDANYEDfefgelTEENQYTEEKDFNLFVNaqvpmsvvngrdgflkfgaktrlknknrendfteygdetgaleflgmv 560
Cdd:COG4771   307 GGSTGSFSD------SDDTTYGLELDLTYPLG------------------------------------------------ 332

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 561 ptrnySDSDFLAGGQYQVgnfaspeflgglnlndsnlfeaENLPEEYITANFDVNENVYAGYAMLNQDLSDKLSVLAGVR 640
Cdd:COG4771   333 -----GNHTLTLGAEYRY----------------------DDLDSSSFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLR 385

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 641 LEHTSIEsegnelefdtegdvsginvvkDKNSYTNILPGVHFKYNLNDNTILRFAWTNTLARPNYVDLvpYREINNEDEE 720
Cdd:COG4771   386 YDYYSTF---------------------GASNYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAEL--YGSGTGTPGR 442

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 721 IFLGNSELDPTTSMNFDVMAEHYFKSVGI-ISGGLFYKDIQDFVYTFQSENEDGFeVYQPLNGDDASVFGAEVSFQRRLD 799
Cdd:COG4771   443 YVLGNPDLKPETSDNYELGLEYRLGNGGLsLSLTGFYTDIKDLIVLVPVGPGPGD-VLQYENVGKARTYGLELELKYRLG 521

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 800 flpgfaKNFSVYLNYTYLTSstdgiRNEDGEerTDLDLPQTAPNMFNGSLGY-AGKNFSLRLSANYSDAYIDEIGGNAFE 878
Cdd:COG4771   522 ------KGLTLTASYTYLDS-----KIDDGD--TGEPLPNVPPHKANLGLDYrLPKWWLLLLLTRYYGGRYVTPPSGRLE 588

                         810       820
                  ....*....|....*....|....*
gi 1601809800 879 DrYYDEQLFLDFNANVAINKNLSLY 903
Cdd:COG4771   589 G-YTPGYTLLDLRASYKLTKNLTLS 612
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
105-930 1.26e-47

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 180.79  E-value: 1.26e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 105 LDEVEVVAYGFGSQARALNTQknktniTNIVSTDQIGKFPDANIGDAVKRIPGITMQVDQGEARNIIVRGLSPQLNSV-- 182
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGS------VSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGGGNRVlv 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 183 TLNGsrIPSAEGDNRNVQMDLIPSDMIQTIEVNK-AVTPDMDGDALGGSVNLITKTSPQGF--RLSATAGSGinfitDKR 259
Cdd:COG1629    75 LVDG--VPLNDPSGGDGGLSYIDPEDIERVEVLRgPSSALYGSGALGGVINIVTKKPKDGKggEVSASYGSY-----GTY 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 260 ILNGSFLVGdrskNNKFGWMVSASINDNDfgsdnveaEWTDefefnNGDEDnleevdvnpyanvfeireylvqrvRRSFS 339
Cdd:COG1629   148 RASLSLSGG----NGKLAYRLSASYRDSD--------GYRD-----NSDSD------------------------RYNLR 186

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 340 ANLDYKLDKNNTVYFKSIYNWRDDrenrfrleheildgedigagdfsvDANGNLTMFPVEAKRQSKGGIDSKRNKNARLE 419
Cdd:COG1629   187 AKLGYQLGDDTRLTLSASYSDSDQ------------------------DSPGYLTLAALRPRGAMDDGTNPYSNDTDDNT 242

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 420 DQRmqnYSLGGEHlfgkvqmdwmasfskaseERLNErYLEYESEYAVNFNNNQDKPLFSPVSATDANYEDFEFgeltEEN 499
Cdd:COG1629   243 RDR---YSLSLEY------------------EHLGD-GLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQTDF----DNR 296

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 500 QYTeekdfnlfVNAQVpmsvvngrDGFLKFGAKTRLknknrendfteygdetgaleflgmvptrnysdsdfLAGGQYQVG 579
Cdd:COG1629   297 TYG--------LELRL--------TYDLGFGGKHTL-----------------------------------LVGLDYQRQ 325

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 580 NFASPEFLGGLNlndsnlfeAENLPEEYITANFDVNENVYAGYAMLNQDLSDKLSVLAGVRLEHTSiesegneleFDTEG 659
Cdd:COG1629   326 DLDGSGYPLDLG--------SGSLPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVS---------YDVDD 388

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 660 DVSGINVVKDKNSYTNILPGVHFKYNLNDNTILRFAWTNTLARPNYVDLVPYREINNEdeeifLGNSELDPTTSMNFDVM 739
Cdd:COG1629   389 TVTGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYS-----VGNPDLKPETSTNYELG 463

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 740 AE-HYFKSVGIISGGLFYKDIQDFVYTFQSENEDGFEVYQpLNGDDASVFGAEVSFQRRldflpgFAKNFSVYLNYTYlt 818
Cdd:COG1629   464 LRyRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFSTYY-TNAGKARSYGVELELSYQ------LTPGLSLNASYSY-- 534

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 819 ssTDGIRNEDGEERTDLD---LPQTAPNMFNGSLGY-AGKNFSLRLSANY-SDAYIDEIGGNAFEDRYYdeqlFLDFNAN 893
Cdd:COG1629   535 --TDAKFDDDTDGSADLDgnrLPGVPPLTANLGLTYeFPGGWSLGLGVRYvGDRYLDDANTQGAPGGYT----LVDLGAG 608

                         810       820       830
                  ....*....|....*....|....*....|....*..
gi 1601809800 894 VAINKNLSLYLNINNITNQplRYYQGVSSRTMQMEYY 930
Cdd:COG1629   609 YRFGDNLTLSLGVDNLFDK--KYATSLSVRASNVRGF 643
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
85-917 4.27e-38

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 152.39  E-value: 4.27e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  85 TVTASQTTELNITLTSKSTELDEVEVVAYGFGsQARALNTQKNktniTNIVSTDQIGKFPDANIGDAVKRIPGITMQVDQ 164
Cdd:COG4772     3 RALAAALLLAAAAAAEAATTLETVVVTGSRAA-EARLKDVPGS----VSVVDREELENQAATSLREVLRRVPGVNVQEED 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 165 GEAR--NIIVRGLSPQLNS-VTL--NGSRI-PSAEGDNrnvQMDLIPS-DMIQTIEVNK---AVTPdmdG-DALGGSVNL 233
Cdd:COG4772    78 GFGLrpNIGIRGLGPRRSRgITLleDGIPIaPAPYGDP---AAYYFPDlERMERIEVLRgaaALRY---GpQTVGGAINF 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 234 ITKTSPQ--GFRLSATAGSGINFitdkrilNGSFLVGDRSKNnkFGWMVSASindnDFGSDnveaewtdefefnnGDEDN 311
Cdd:COG4772   152 VTRTIPTafGGELRVTGGSFGYR-------RTHASVGGTVGN--FGYLVEYS----RKRGD--------------GFRDN 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 312 lEEVDVNpyanvfeireylvqrvrrSFSANLDYKLDKNNTVYFKSIYnwrddrenrfrleheildgedigagdFSVDAN- 390
Cdd:COG4772   205 -SGFDIN------------------DFNAKLGYRLSDRQELTLKFQY--------------------------YDEDANt 239

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 391 -GNLTMFPVEA-KRQSKGGIDSKrnknarleDQRMQNYSLGGEHLFG-KVQMDWMAsfskaseerlneryleyeseYAVN 467
Cdd:COG4772   240 pGGLTDAQFDAdPRQSYRPADQF--------DTRRTQLSLRYEHQLSdNTTLTTTA--------------------YYND 291

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 468 FNNNQdkplFSPVSATDANYEdfefgelteenqyteekdfnlfvnaqvPMSVVNGRDGFLKFGAKTRLknknrendftey 547
Cdd:COG4772   292 FSRNW----YIRQNTADPNTP---------------------------GLGLRGNPRGYRSYGIEPRL------------ 328

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 548 gdeTGALEFLGMvptrnysDSDFLAGGQYQVGNFASPEFLG-------GLNLNDSNLFEAENlpeeyitanfdvnenvYA 620
Cdd:COG4772   329 ---THRFELGGV-------PHTLEVGLRYHREEEDRKQYVNtygqgrsGAGLRRDRRFSADA----------------LA 382

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 621 GYAMLNQDLSDKLSVLAGVRLEHTSIESEGNeLEFDTEGDVSGinvvkdKNSYTNILPGVHFKYNLNDNTILrFAWTNTL 700
Cdd:COG4772   383 AYAQNRFELTGRLTLTPGLRYEHIRRDRTDR-YSTRTGGDDSG------SNSYSEFLPGLGLLYQLTDNLQL-YANVSRG 454

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 701 ARPnyvdlVPYREINNEDEeiflGNSELDPTTSMNFDVMAEhyFKSVGIISG--GLFYKDIQDFVYTFQSENEDGFEVYq 778
Cdd:COG4772   455 FEP-----PTFGDLAYGNG----GNPDLKPEKSWNYELGTR--GRIGNGLSAevALFYIDYDNELGSCSAAGGDRSTFT- 522

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 779 plNGDDASVFGAEVSFqrRLDFLPGFAKNFSVYLNYTYLTSStdgIRNEDGEERTDLDLPQTAPNMFNGSLGYAGKNFSL 858
Cdd:COG4772   523 --NAGETRHQGLELAL--DYDLLKGGGLGLPLFAAYTYTDAE---FTSDFGPVFAGNRLPYVPRHQLTAGLGYEHGGWTA 595

                         810       820       830       840       850       860
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1601809800 859 RLSANY-SDAYIDeiGGNAFEDRYY---DEQLFLDFNANVAINKNLSLYLNINNITNQplRYY 917
Cdd:COG4772   596 NLNGRYvSEQFTD--AANTVADGSFgkiPSYTVLDLSASYDFGKNLSLFAGVNNLFDK--RYI 654
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 464-941 8.93e-30

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 124.11  E-value: 8.93e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 464 YAVNFNNNQDKPLFSPVSATDANYEDFEFGELTEENQYTEEKDFNLFVNAQVPMSVVNGRDGFLKFGAKTRLKNKNREND 543
Cdd:pfam00593  34 LDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 544 FTEYGDETGALEFLGMVPTRNYSDSDFLAGGQYQVGNFASPEFLGGLNLNDSNlfeaenlpeeyitaNFDVNENVYAGYA 623
Cdd:pfam00593 114 YGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSS--------------YSDTTTDSYGLYL 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 624 MLNQDLSDKLSVLAGVRLEHtsiesegneleFDTEGDVSGINVVKDKNSYTNILPGVHFKYNLNDNTILRFAWTNTLARP 703
Cdd:pfam00593 180 QDNIKLTDRLTLTLGLRYDH-----------YSTDGDDGNGGGDNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAP 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 704 NYVDLVPYReINNEDEEIFLGNSELDPTTSMNFDVMAEhYFKSVGIISGGLFYKDIQDFVYTFQSENEDGFEVYQPLNGD 783
Cdd:pfam00593 249 SLGELYGSG-SGGGGGAVAGGNPDLKPETSDNYELGLK-YDDGRLSLSLALFYIDIKNLITSDPDGPGLGGTVYTYTNVG 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 784 DASVFGAEVSFQRRLdFLPGFAKNfsvylNYTYLTSSTDGIRNEDGEertdlDLPQTAPNMFNGSLGY--AGKNFSLRLS 861
Cdd:pfam00593 327 KARIRGVELELSGRL-WGLGLSGG-----GYTYTDADDDADADDTGN-----PLPNVPRHTANLGLTYdfPLGGWGARLG 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 862 ANYSDAYiDEIGGNAFEDRYYDEQLFLDFNANVAINKNLSLYLNINNITNQPLRYYQGVSSRTMQMEYYEKR-LTFGLKY 940
Cdd:pfam00593 396 ARYVGSG-ERRYGDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNLGGYPGPGRtFYLGLSY 474


                  .
gi 1601809800 941 D 941
Cdd:pfam00593 475 K 475
OMP_b-brl_3 pfam14905
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ...
 590-940 1.83e-22

Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.


Pssm-ID: 434300 [Multi-domain]  Cd Length: 407  Bit Score: 101.20  E-value: 1.83e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 590 LNLNDSNLFEAENLPEEYI-----TANFDVNENVYAGYAMLNQDLSdKLSVLAGVRLEHTSIESEgneleFDTEGDVsgi 664
Cdd:pfam14905  81 FRNNDNDYDYENLDNGEWVpdpsrSNDFDYKENIYAAYASYSKKFG-KWSYQAGLRAEYTDIDGD-----SVTTNET--- 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 665 nvvkDKNSYTNILPGVHFKYNLNDNTILRFAWTNT--LARPNYVDLVPYREINNEdEEIFLGNSELDPTTSMNFDVMAEH 742
Cdd:pfam14905 152 ----FKRNYFNLFPSASLSYKLNDNNSLQLSLYYRriINRPSYWDLNPFRNYSDP-YNYSQGNPNLKPEYTNSFELGYTY 226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 743 YFKsvgiISGGLFYKDIQD-FVYTFQSENEDGFEVYQPLNGDDASVFGAEVSFQrrLDFLPGFakNFSVYLNYTYLTSST 821
Cdd:pfam14905 227 KWK----LSLSLSYRYTNDvIQQTFITDDNDNVTYTTYENLGKSNSYGLELSAS--FNPTKWW--SLNGNLNGYYNKYKI 298

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 822 DGIRNEDGEERTdldlpqtapNMFNGSLGY-AGKNFSLRLSANYSDAYIDEIGgnafedrYYDEQLFLDFNANVAI-NKN 899
Cdd:pfam14905 299 DGSLNSDFSNFG---------FNWNLNNTFtLPKGWSLQLNGNYRSPRVTGQG-------KIKPFYSLDLGLSKSFlKKK 362

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1601809800 900 LSLYLNINNITNQPLR----YYQGVSSRTMQMEYYEKRLTFGLKY 940
Cdd:pfam14905 363 LTLSLNVNDIFNTRKFrsttNYDNGFIQSYNNKWDSRSVRLSLSY 407
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
108-369 8.29e-20

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 90.70  E-value: 8.29e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 108 VEVVAYGFGSQARALntqknkTNITNIVSTDQIGKFPDANIGDAVKRIPGITMQVD--QGEARNIIVRGLSPQLNSVTLN 185
Cdd:COG4206     1 VVVTATRLEQSKSDL------TGSVTVIDAEELERSGATSLADALRRVPGVQVSSSggPGSAASISIRGLGSNQTLVLID 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 186 GsrIPSAEGDNRNVQMDLIPSDMIQTIEVNKAVTPDMDG-DALGGSVNLITKTSPQGFRLSATAGSGiNFITDKRILNGS 264
Cdd:COG4206    75 G--VPLNDPSLGGVDLSLIPPDDIERIEVLKGAASALYGsDAIGGVINITTKKGKKGFKGSVSASYG-SFGTRRLSASLS 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 265 FlvgdrsKNNKFGWMVSAS-INDNDFGSDNVEAEWTDEFEFNNG--------DEDNLEEVDVNPYANVFEIREYLVQRVR 335
Cdd:COG4206   152 G------GAGKFSYSLSASyRRSDGYRYNDPDLRNNDGYENTSLnarlgyklGDNGSLSLSGGYSDSERGYPGAVGSDRN 225

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1601809800 336 RSFSANLDYKLDKNNTVYFKSIYNWRDDRENRFR 369
Cdd:COG4206   226 LRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGG 259
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
 24-110 1.46e-19

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 84.18  E-value: 1.46e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  24 LQGIITDDN-GITVPGATVMIEELKKAVVSDFDGKFTMVDIPEGTYNLLIKYLGYADFKQEVTVTASQTTELNITLTSKS 102
Cdd:pfam13715   1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKNLPAGTYTLVVSFVGYKTQEKKVTVSNDNTLDVNFLLKEDA 80


                  ....*...
gi 1601809800 103 TELDEVEV 110
Cdd:pfam13715  81 LLLDEVVV 88
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 24-216 4.94e-19

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 93.04  E-value: 4.94e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  24 LQGIITDDNGITVPGATVMIEELKKAVVSDFDGKFTMVDIPEGTynLLIKYLGYAdfKQEVTVTASQTteLNITLTSKST 103
Cdd:TIGR04056   3 VTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAV--LVFSYIGYK--TQEVKVKGQKN--LNITLKEDTQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 104 ELDEVEVVAYGfgsqaralnTQKNKTNITNI--VSTDQIGKFPDANIGDAVK-RIPGITMQVDQGE---ARNIIVRGLSp 177
Cdd:TIGR04056  77 ELDEVVVVGYG---------TQKKKSLTGAVstVKAKELKKVPVSNLSNALQgKVAGVIITQSSGEpggDAEIWIRGIS- 146

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1601809800 178 qlnsvTLNGSRIP-----SAEGDNrnvQMDLIPSDMIQTIEVNK 216
Cdd:TIGR04056 147 -----SFGGNNSPlyvidGVPRDN---GLSDLNPEDIESISVLK 182
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 124-229 4.59e-17

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 77.69  E-value: 4.59e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 124 TQKNKTNITNIVSTDQIGKFPDANIGDAVKRIPGITMQVDQ-GEARNIIVRGLSPQLNSVTLNGsrIPSAEGDNRNVQMD 202
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVSVSSGGgGGGSSISIRGFGSNRVLVLVDG--VPLNSGGGGSVDLN 78

                          90       100
                  ....*....|....*....|....*...
gi 1601809800 203 LIPSDMIQTIEVNK-AVTPDMDGDALGG 229
Cdd:pfam07715  79 SIDPEDIERVEVLKgPASALYGSGAIGG 106
CarboxypepD_reg pfam13620
Carboxypeptidase regulatory-like domain;
24-98 2.59e-15

Carboxypeptidase regulatory-like domain;


Pssm-ID: 433354 [Multi-domain]  Cd Length: 81  Bit Score: 71.54  E-value: 2.59e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  24 LQGIITDDNGITVPGATVMIE----ELKKAVVSDFDGKFTMVDIPEGTYNLLIKYLGYADFKQE-VTVTASQTTELNITL 98
Cdd:pfam13620   2 ISGTVTDPSGAPVPGATVTVTntdtGTVRTTTTDADGRYRFPGLPPGTYTVTVSAPGFKTATRTgVTVTAGQTTTLDVTL 81
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 86-924 2.80e-12

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 70.69  E-value: 2.80e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  86 VTASQTTELNITLTSKSTELDEVEVVAYGFGSQARALNTQK--NKTNIT--------NIVSTDQIGKFPDANIGDAVKRI 155
Cdd:COG4773    13 AAAGALAQAAAAAAAEATTLPEVTVTGTAEGTGGYTAKSSStaTKLDTPlretpqsvSVVTRQLIEDQGATTLDDALRNV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 156 PGITMQVDQGEAR-NIIVRGLspQLNSVTLNGSRIPSAegdnRNVQMDLIpsdMIQTIEVNK--------AVTPdmdgda 226
Cdd:COG4773    93 PGVTVSSYDGGGRdSFSIRGF--SIDNYLRDGLPLGGF----GGGQPDTA---NLERVEVLKgpagllygAGSP------ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 227 lGGSVNLITK--TSPQGFRLSATAGSGiNFitdKRI---LNGSFlvgdrSKNNKFGWMVSASINDNDFGSDNVEAEwtde 301
Cdd:COG4773   158 -GGLVNLVTKrpTAEPQGEVSLSAGSW-DT---YRAtadVGGPL-----NEDGTLRYRLNAAYEDGDSFRDGVDNR---- 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 302 fefnngdednleevdvnpyanvfeireylvqrvRRSFSANLDYKLDKNNTVYFKSIYNWRDDRENRFRLeheildgedig 381
Cdd:COG4773   224 ---------------------------------RTLIAPSLDWDLTDDTTLTLGAEYQDDDSTGDRGFL----------- 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 382 agdfsvDANGNLTmfpveakrqskgGIDSKRNKNARLEDQRMQNYSLGG--EHLFGKvqmDWMAsfskaseeRLNERYLE 459
Cdd:COG4773   260 ------PLDGTLL------------DLPRSTNLGEPWDYYDTETTTLFAelEHRFND---DWSL--------RANARYSD 310

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 460 YESEYAVNFNNNqdkplfspvsatdanYEDFEFGELTEENQYTEEKDFNLFVNAQVpmsvvNGrdgflKFgaktrlknkn 539
Cdd:COG4773   311 SDRDGRSAYAYG---------------APDAATGTLTRYASARDGDSRSDSLDANL-----NG-----KF---------- 355

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 540 rendfteygdETGALEflgmvptrnysdSDFLAGGQYQVGNFASPEF-LGGLNLNDSNlfeAENLPE-EYITANFDVNEN 617
Cdd:COG4773   356 ----------ETGGLE------------HTLLVGADYSRYDSDSDSAtAGTINIYNPV---YGNLPEpDFDASDTDTTTR 410

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 618 VYAGYAMLNQDLSDKLSVLAGVRleHTSIESEGNelefdtegdvSGINVVKDKNSYTNILPGVHFKYNLNDNTILRFAWT 697
Cdd:COG4773   411 QTGLYAQDQISLTDRLSLLLGGR--YDWYETDST----------NRLGGSTTSYDDSAFTPRAGLVYDLTPGLSLYASYS 478

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 698 NTLARPNYVDLvpyreinnedeeiflGNSELDPTTSMNFdvmaEhyfksVGI----------ISGGLFykDI-QDFVYTF 766
Cdd:COG4773   479 ESFEPQSGADN---------------NGNPLDPETGKQY----E-----AGVkgelfdgrlnATLAVF--DItQKNVATT 532

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 767 QSENEDGFEvyqplNGDDASVFGAEVSFQRRLdflpgfAKNFSVYLNYTYltssTDGIRNEDGEERTDLDLPQTAPNMFN 846
Cdd:COG4773   533 DPDNPNFYV-----QVGEVRSRGVELELSGEL------TPGLNLIAGYTY----TDAKITKDADALEGKRLTNVPRHTAS 597

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 847 GSLGY-----AGKNFSLRLSANY-SDAYIDeiGGNAFEdryYDEQLFLDFNANVAINKNLSLYLNINNITNQplRYYQGV 920
Cdd:COG4773   598 LWTTYrfpsgALKGLGLGGGVRYvGERYGD--AANTFT---LPSYTLVDAGARYDLGKNWTLQLNVNNLFDK--KYYASS 670


                  ....
gi 1601809800 921 SSRT 924
Cdd:COG4773   671 GSRG 674
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
147-925 7.89e-10

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 62.59  E-value: 7.89e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 147 NIGDAVKRIPGITMQVDQGEAR-NIIVRGLSPQlNSVTLNGSRIPSaegdnrnvqMDLIPSDMIQTIEVNK---AVtpdM 222
Cdd:COG4774    28 SLADALRNVPGVTFGAGEGGNGdSFSIRGFSAS-GDIYVDGLRDPG---------QYRRDTFNLERVEVLKgpaSV---L 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 223 DGD-ALGGSVNLITKTsPQ---GFRLSATAGSGinfiTDKRI---LNGSFlvgdrskNNKFGWMVSASINDNDFGSDNVE 295
Cdd:COG4774    95 YGRgSPGGVINLVTKR-PTdepFTEVTLTYGSD----GQRRAtldVNGPL-------GDDLAYRLNGMYRDSDSYRDGVD 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 296 AEwtdefefnngdednleevdvnpyanvfeireylvqrvRRSFSANLDYKLDKNNTVYFKSIYNWRDDRENRFrleheil 375
Cdd:COG4774   163 ND-------------------------------------RWGIAPSLTWRLGDRTRLTLDYEYQDDDRTPDYG------- 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 376 dgedigagdFSVDANGNLTmfpveakrqskgGIDSKRNKNAR--LEDQRMQNYSLGGEHLFGKvqmDWMAsfskaseeRL 453
Cdd:COG4774   199 ---------VPAVANGRPV------------DVDRSTFYGQPddYSDSETDSATLRLEHDFND---NWTL--------RN 246

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 454 NERYLEYESEYavnfnnnqdkpLFSPVSATDANyedfefGELTEENQYTEEKDFNLFVNAQVpmsvvngrdgflkfgakt 533
Cdd:COG4774   247 ALRYSDYDRDY-----------RNTYPTGGNAT------GTVTRSAYRRDQDNDTLSNQTDL------------------ 291

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 534 rlknknrENDFteygdETGALEflgmvptrnysdSDFLAGGQYQVGNFASPEFLGGLNLNDSNLFE----AENLPEEYIT 609
Cdd:COG4774   292 -------TGKF-----DTGGVK------------HTLLAGVEYSREDSDNARYSGGGTAPTVNLYNpvygAPVTGPTLGG 347

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 610 ANFDVNENVYAGYAMLNQDLSDKLSVLAGVRLEHtsiesegneleFDTEGDVSGINVVKDKNSYTNILPGVHFKYNLNDN 689
Cdd:COG4774   348 ADNDSRTDTTGLYLQDTISLTDRWSLLAGLRYDR-----------FDTDYTDRTTGATTSSYDDSAFSPRAGLVYKPTPN 416

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 690 TILRFAWTNTLaRPNyvDLVPYREINNEDeeiflgnseLDPTTSMNFDVmaehyfksvGI----------ISGGLFYKDi 759
Cdd:COG4774   417 LSLYASYSTSF-NPG--GGAPSLSNAGQA---------LDPEKSRQYEV---------GVkwdlldgrlsLTAALFRIE- 474

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 760 QDFVYTFQSENEDGFevyqpLNGDDASVFGAEVSFQRRLdflpgfAKNFSVYLNYTYL----TSSTDGirNEDGeertdL 835
Cdd:COG4774   475 KTNVRTTDPANPGVY-----VQTGEQRSRGVELEATGEL------TPGWSVLAGYTYLdaeiTKSANA--ANVG-----N 536

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 836 DLPQTAPNMFNGSLGYA--GKNFSLRLSANY-SDAYIDEigGNAFedrYYDEQLFLDFNANVAINKNLSLYLNINNITNQ 912
Cdd:COG4774   537 RLPNVPRHSASLWTTYDlpLPGLTLGGGVRYvGSRYADA--ANTV---KLPSYTRFDAGASYRLNKNLTLRLNVNNLTDK 611

                         810
                  ....*....|...
gi 1601809800 913 plRYYQGVSSRTM 925
Cdd:COG4774   612 --RYYASAYGSGY 622
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
96-912 2.17e-09

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 61.18  E-value: 2.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  96 ITLTSKSTELDEVE---VVAYGFGSQaralntQKNKTNITNIVSTDQIGKFPDANIGDAVKRIPGITMQvDQGEARNIIV 172
Cdd:PRK13484   18 VISSGYASSDKKEDtlvVTASGFTQQ------LRNAPASVSVITSEQLQKKPVSDLVDAVKDVEGISIT-GGNEKPDISI 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 173 RGLSPQLNSVTLNGSRIPSAEG---DNRNVQMDLI-PSDMIQTIEVNKAVTPDMDG-DALGGSVNLITK-TSPQGFRLSA 246
Cdd:PRK13484   91 RGLSGDYTLILVDGRRQSGRESrpnGSGGFEAGFIpPVEAIERIEVIRGPMSSLYGsDAIGGVINIITKpVNNQTWDGVL 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 247 TAGSGINFitdkrilNGSFlvGDrSKNNKF---GWMVSASINDNDFGSDNVEAEwtDEFEFNNGDEDNleevdvnpyanv 323
Cdd:PRK13484  171 GLGGIIQE-------HGKF--GN-STTNDFylsGPLIKDKLGLQLYGGMNYRKE--DSISQGTPAKDN------------ 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 324 feireylvqrvrRSFSANLDYKLDKNNTVYFKSiynwrddreNRFRLEHEILDGEDIGAgdfsvdangnLTMfpveakrq 403
Cdd:PRK13484  227 ------------KNITATLQFTPTESQKFVFEY---------GKNNQVHTLTPGESLDA----------WTM-------- 267

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 404 sKGGidsKRNKNARLEDQRMQNYslggehlfgkvqmdWMASFskaseerlneryleyeseyavnfnNNQDKPLFSPVSAt 483
Cdd:PRK13484  268 -RGN---LKQPNSKRETHNSRSH--------------WVAAW------------------------NAQGEILHPEIAV- 304

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 484 danyedfeFGELTEENQYTEEKDfnlfvnaqvpmsVVNGRDgflkfgaktrLKNKNRENDFTEYGDETGALEFLgmvptr 563
Cdd:PRK13484  305 --------YQEKVIREVKSGKKD------------KYNHWD----------LNYESRKPEITNTIIDAKVTAFL------ 348

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 564 nySDSDFLAGGQYQVGNFASPEFLGGLNLNDSNLFEAENlpeeyitANFDVNEnvyagYAMlnqdlSDKLSVLAGVRLEH 643
Cdd:PRK13484  349 --PENVLTIGGQFQHAELRDDSATGKKTTETQSVSIKQK-------AVFIENE-----YAA-----TDSLALTGGLRLDN 409

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 644 TSIesegnelefdtegdvsginvvkdKNSYTNilPGVHFKYNLNDNTILRFAWTNTLARPNYVDLVP-YREINNEDEEIF 722
Cdd:PRK13484  410 HEI-----------------------YGSYWN--PRLYAVYNLTDNLTLKGGIAKAFRAPSIREVSPgFGTLTQGGASIM 464

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 723 LGNSELDPTTSMNFDVMAEHYFKSVGIISGGLFYKDIQDFVYTFQSENED---GFEVYQPLNGDDASVFGAEVSFQrrld 799
Cdd:PRK13484  465 YGNRDLKPETSVTEEIGIIYSNDSGFSASATLFNTDFKNKLTSYDIGTKDpvtGLNTFIYDNVGEANIRGVELATQ---- 540

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 800 fLPgFAKNFSVYLNYTYltssTDGIRNED-----GEERTDLDLPQTAPNMFNGSLGYA-GKNFSLRLSANYSDAYIDEIG 873
Cdd:PRK13484  541 -IP-VYDKWHVSANYTF----TDSRRKSDdeslnGKSLKGEPLERTPRHAANAKLEWDyTQDITFYSSLNYTGKQIWAAQ 614

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|
gi 1601809800 874 GNAFE-DRYYDEQLFLDFNANVAINKNLSLYLNINNITNQ 912
Cdd:PRK13484  615 RNGAKvPRVRNGFTSMDIGLNYQILPDTLINFAVLNVTDR 654
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 133-252 1.31e-08

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 58.74  E-value: 1.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 133 NIVSTDQIGKFPDANIGDAVKRIPGITMQVDQGEARNIIVRGLSPQLNSVTLNGSRIPSAEGDNRNVQMDL--IPSDMIQ 210
Cdd:PRK10064   52 SVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLILIDGKRVNSRNAVFRHNDFDLnwIPVDAIE 131

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1601809800 211 TIEVNKAVTPDMDG-DALGGSVNLITKTSPQGFRLSATAGSGI 252
Cdd:PRK10064  132 RIEVVRGPMSSLYGsDALGGVVNIITKKIGQKWHGTVTVDTTI 174
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 134-924 1.98e-08

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 58.19  E-value: 1.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 134 IVSTDQIGKFPDANIGDAVKRIPGITMQVDQGEAR--NIIVRGLSP--QLNSVTLNGSRIPSAEGDnrnvqmDLIPSDMI 209
Cdd:TIGR01783   8 VITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQfgNITIRGFGLevDIDNVYLDGVPLLSRGNL------AIVDPAMV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 210 QTIEVNKAVTPDMDG-DALGGSVNLITKTSPQGFRLSATAGSGINfitDKRilNGSFLVGDR-SKNNKFGWMVSASINDN 287
Cdd:TIGR01783  82 ERVEVLRGPASLLYGgSAPGGVINIVTKRPQDEPKGSVTFGAGTR---SGY--RTAFDLGGPlGADGTFRGRLNGARQDG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 288 dfgsdnveaewtDEFEFNNGDEdnleevdvnpyanvfeireylvqrvRRSFSANLDYKLDKNNTVYFKSIYNWRDDRENR 367
Cdd:TIGR01783 157 ------------DSFYDGAGEE-------------------------TRLGATATDWQLDDRTLLRLGAYYQKERDRGGY 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 368 FRLEHEildgEDIGAGDFSVDANgnltmfpveakrqskGGIDSKRNKNARledqRMQNYSLGGEHLFGKV-QMDWMASFS 446
Cdd:TIGR01783 200 GGLPAS----GGTSGRDLSSDRY---------------LGTSSNRNYDDR----EYLSYGLSLEYQFNDVwTGKQNLRYS 256

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 447 kaseerlnerYLEYESEYAVNFNNNQDKPLFSPVSATDANYEDFEFGELteenqyTEEKDFNLFvnaqvpmsvvnGRDGF 526
Cdd:TIGR01783 257 ----------YFDTDSNQVQASGYSSDGGLFGRSLTVVNVKQDRVQIDA------GLDGEFETG-----------PIEHD 309

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 527 LKFGAKTRLKNKNRENDFTEYGDETGALEFLGmvptrnysdsdflaGGQYQVGNFASPEFLgglnlndSNLFEAENlpee 606
Cdd:TIGR01783 310 LLLGVSYGQRTTNRFNNTGYPSDNIYSLTATS--------------SARTDIGDSPKDRAL-------SSTTKALN---- 364

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 607 yitanfdvnenvyaGYAMLNQDLSDKLSVLAGVRLEHTSIESEgnelefdtegdvSGINVVKDKNSYTNILPGVHFKYNL 686
Cdd:TIGR01783 365 --------------GVALQRILLADKWTLTLGGRYDSVDVKSN------------NGVAGSTGKRDDSQFTPSLGVAYKP 418

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 687 NDNTILRFAWTNTLARPNYVDLVPYReinnedeeiflGNSELDPTTSMNFDVMAEHYFKSVGIISGGLFYkdiQDFVYTF 766
Cdd:TIGR01783 419 TDDWSLYASYAESFKPGGYYPKGAGN-----------SGDILEPEKGKNYELGVRYDLGDSLLATAALFR---ITKDNQL 484

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 767 QSENEDGFEVyqpLNGDDASVFGAEVSFQRRLDFlpgfakNFSVYLNYTYltssTDGIRNEDGEERTDL-DLPQTAPNMF 845
Cdd:TIGR01783 485 VQDPVNGTFS---VNAGKTRNRGVELEARGYLTP------GLSLSAGYTY----TDAEFTEDTNGDTQGnTVPFVPKHTA 551

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 846 NGSLGYAGKNFSLRLSANYSDAYIDEIGGNAFEDRYYDEQLFLDFNAN--VAINKNLSLYLNINNITNQplRYYQGVSSR 923
Cdd:TIGR01783 552 SLWASYAPPVGDNGLTLGGGVQYTGKAYVDGGNTGKVPSYTVVDLSVRydLTKKKNLTLALNVNNLFDR--DYYTSGYRW 629


                  .
gi 1601809800 924 T 924
Cdd:TIGR01783 630 G 630
Peptidase_M14NE-CP-C_like cd11308
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, ...
 26-98 6.48e-08

Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.


Pssm-ID: 200604 [Multi-domain]  Cd Length: 76  Bit Score: 50.60  E-value: 6.48e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1601809800  26 GIITDDNGITVPGATVMIEELKKAVVSDFDGKFTMVDIPeGTYNLLIKYLGYADFKQEVTVTAS-QTTELNITL 98
Cdd:cd11308     4 GFVTDATGNPIANATISVEGINHDVTTAKDGDYWRLLLP-GTYNVTASAPGYQPVTKTVTVPNNfSATVVNFTL 76
PRK13513 PRK13513
ligand-gated channel protein;
99-247 2.53e-06

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 51.31  E-value: 2.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800  99 TSKSTELDEVEVVAYGFGSQaralnTQKNKTNITnIVSTDQIGKFPDANIGDAVKRIPGItMQVDQGEARNIIVRGLSPQ 178
Cdd:PRK13513   29 TNTATPTDTMVVTASGFQQR-----IQDAPASIS-VVTREQLENKAYRDVTDALKDVPGV-VVTGGGSTSDISIRGMAAK 101

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1601809800 179 LNSVTLNGSRIPSAE----GDNRNV-QMDLIPSDMIQTIEVNKAVTPDMDG-DALGGSVNLITKTSPQG----FRLSAT 247
Cdd:PRK13513  102 YTLILVDGKRVDTRStrpnSDGSGIeQGWLPPLAAIERIEVVRGPMSSLYGsDAMGGVINIITRKVQKEwhgsLRADAT 180
PEGA pfam08308
PEGA domain; This domain is found in both archaea and bacteria and has similarity to S-layer ...
 37-98 4.13e-06

PEGA domain; This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteriztic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].


Pssm-ID: 429908 [Multi-domain]  Cd Length: 71  Bit Score: 45.37  E-value: 4.13e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1601809800  37 PGATVMIeelkkavvsdfDGKF------TMVDIPEGTYNLLIKYLGYADFKQEVTVTASQTTELNITL 98
Cdd:pfam08308  11 EGATVYI-----------DGNYlgktpvTVSDLPAGTYSVRLEKEGYEDYEKTVTVTAGETVKLNLTL 67
PRK13483 PRK13483
ligand-gated channel protein;
724-916 1.11e-04

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 45.92  E-value: 1.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 724 GNSELDPTTSMNFDVmAEHYFKSVGIISG-GLFYKDIQDFV--------YTFQSENEDGFEVYQPLNGDDASVFGAEVSF 794
Cdd:PRK13483  451 GNPDLKPETSLNKEL-GLYYDLGSGLTASlTVFYNEFKDKItrvacpatQCTDGPNQFGADPTTYVNIDEAVTQGVEASL 529

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 795 QRRLdflpgfAKNFSVYLNYTYltsstdgirnEDGEERTD----LDLPQTAPNMFNGSLGYA-GKNFSLRLSANYSDAYI 869
Cdd:PRK13483  530 SYPI------TSTLSLSGNYTY----------TDSEQKSGaykgSPLNQLPKHLFQASLNWEpTDRLNSWARVNYRGEES 593

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1601809800 870 DEIGGNAFEDRYYDEQLFLDFNANVAINKNLSLYLNINNITNQPLRY 916
Cdd:PRK13483  594 QPTTGPSSSSFIAPSYTFLDLGANYQLTDNLKLSAGIYNLFDKEINY 640
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 678-923 2.38e-04

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 44.88  E-value: 2.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 678 PGVHFKYNLNDNTILRFAWTNTLARPNYVDLVPYREINNEDEEIFL-GNSELDPTTSMNFDvMAEHYFKSVGIISG---- 752
Cdd:PRK10064  396 PRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIvGSPDLKPETSESWE-LGLYYMGEEGWLEGvess 474

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 753 -GLFYKDIQD------------------FVYTFQSENEDGFEVYQPLNGDDASVFGAEVSFQrrldfLPgFAKNFSVYLN 813
Cdd:PRK10064  475 vTVFRNDVDDrisisrtsdvnaapgyqnFVGFETNGRGRRVPVFRYYNVNKARIQGVETELK-----IP-FNDEWKLSLN 548

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 814 YTYltssTDGIRNEDGEERTDLDLP-QTApnmfNGSLGY---AGKNFSLRLSANYSDAYIDEIGGNAFEDRYydeqLFLD 889
Cdd:PRK10064  549 YTY----NDGRDVSNGENKPLSDLPfHTA----NGTLDWkplALEDWSFYVSGNYTGQKRADSATAKTPGGY----TIWN 616

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1601809800 890 FNANVAINKNLSLYLNINNITNQPL------------RYYQGVSSR 923
Cdd:PRK10064  617 TGAAWQVTKDVKLRAGVLNLGDKDLsrddysynedgrRYFMAVDYR 662
PRK13483 PRK13483
ligand-gated channel protein;
147-247 7.51e-04

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 43.23  E-value: 7.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 147 NIGDAVKRIPGITMqVDQGEARNIIVRGLSPQLNSVTLNGSRIPSAE----GDNRNVQMDLIPS-DMIQTIEVNKAVTPD 221
Cdd:PRK13483   69 DLTDALLDVPGVVV-TGGGDRTDISLRGMGSQYTLILVDGKRQSSREtrpnSDGPGVEQAWTPPlAAIERIEVIRGPMSS 147

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1601809800 222 MDG-DALGGSVNLITKTSPQGF----RLSAT 247
Cdd:PRK13483  148 LYGsDAIGGVINIITRKVPNEWqgevRLDTT 178
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 822-941 7.63e-03

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 39.84  E-value: 7.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601809800 822 DGIRNEDGEERTDLDLPQTAPNMFNGSLGYAGKNFSLRLSANY--SDAYIDEIGGNAFEDRYYDEQLFLdFNANVAINKN 899
Cdd:COG4771   155 KPTDELEGSVSLGYGSNGNGTYSGSLSLGGPGDKLSFLLSGSYrdRDGYLDYRNGGFVGNSGYERYNLN-AKLGYRLSDN 233

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1601809800 900 LSLYLNIN------NITNQPLRYYQGVSSRTMQMEYYEKRLTFGLKYD 941
Cdd:COG4771   234 HRLSLSGGysrqdrDGGPPTLGDTEISSDNAGDRDTTTDRGNYSLRYN 281
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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