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Conserved domains on  [gi|1604907081|ref|WP_134695735|]
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MULTISPECIES: polyprenyl diphosphate synthase [Aeromonas]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10000255)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates, similar to UPPS that catalyzes chain elongation of FPP by eight IPP to form the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis

Gene Ontology:  GO:0016765|GO:0000287|GO:0002094
PubMed:  22471620

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
13-248 1.64e-155

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


:

Pssm-ID: 439791  Cd Length: 248  Bit Score: 432.17  E-value: 1.64e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  13 SSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLG 92
Cdd:COG0020    13 GNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYLR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  93 REVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDE 172
Cdd:COG0020    93 RELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDIDE 172

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1604907081 173 AALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFGCTGEQI 248
Cdd:COG0020   173 ETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
13-248 1.64e-155

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 432.17  E-value: 1.64e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  13 SSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLG 92
Cdd:COG0020    13 GNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYLR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  93 REVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDE 172
Cdd:COG0020    93 RELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDIDE 172

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1604907081 173 AALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFGCTGEQI 248
Cdd:COG0020   173 ETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 10-250 7.46e-132

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 372.48  E-value: 7.46e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  10 SAGSSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMT 89
Cdd:PRK14836    9 PANENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLK 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  90 VLGREVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEA 169
Cdd:PRK14836   89 ALDREVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAPDE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 170 VDEAALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFGCTGEQIR 249
Cdd:PRK14836  169 IDEALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFGKTSAQIA 248


                  .
gi 1604907081 250 E 250
Cdd:PRK14836  249 D 249
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 18-234 1.90e-128

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 362.46  E-value: 1.90e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  18 HVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGREVQK 97
Cdd:cd00475     1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  98 LHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDEAALGR 177
Cdd:cd00475    81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1604907081 178 EVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASF 234
Cdd:cd00475   161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDY 217
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 22-242 1.34e-124

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 352.82  E-value: 1.34e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  22 IMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMT-VLGREVQKLHE 100
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEeYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 101 NGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAagELDAEAVDEAALGREVC 180
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGK--KLDPEDIDEELISSHLY 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1604907081 181 MADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:pfam01255 159 TAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 17-242 2.40e-119

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 340.15  E-value: 2.40e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  17 RHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGREVQ 96
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  97 KLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDEAALG 176
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1604907081 177 REVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:TIGR00055 161 KHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
13-248 1.64e-155

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 432.17  E-value: 1.64e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  13 SSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLG 92
Cdd:COG0020    13 GNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYLR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  93 REVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDE 172
Cdd:COG0020    93 RELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDIDE 172

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1604907081 173 AALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFGCTGEQI 248
Cdd:COG0020   173 ETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 10-250 7.46e-132

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 372.48  E-value: 7.46e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  10 SAGSSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMT 89
Cdd:PRK14836    9 PANENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLK 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  90 VLGREVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEA 169
Cdd:PRK14836   89 ALDREVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAPDE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 170 VDEAALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFGCTGEQIR 249
Cdd:PRK14836  169 IDEALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFGKTSAQIA 248


                  .
gi 1604907081 250 E 250
Cdd:PRK14836  249 D 249
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 18-234 1.90e-128

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 362.46  E-value: 1.90e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  18 HVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGREVQK 97
Cdd:cd00475     1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  98 LHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDEAALGR 177
Cdd:cd00475    81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1604907081 178 EVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASF 234
Cdd:cd00475   161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDY 217
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 22-242 1.34e-124

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 352.82  E-value: 1.34e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  22 IMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMT-VLGREVQKLHE 100
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEeYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 101 NGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAagELDAEAVDEAALGREVC 180
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGK--KLDPEDIDEELISSHLY 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1604907081 181 MADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:pfam01255 159 TAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
23-244 4.50e-120

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 341.96  E-value: 4.50e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  23 MDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGREVQKLHENG 102
Cdd:PRK10240    1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 103 IRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDEAALGREVCMA 182
Cdd:PRK10240   81 VRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQPDQIDEEMLNQHICMH 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1604907081 183 DLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFGCT 244
Cdd:PRK10240  161 ELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGT 222
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 17-242 2.40e-119

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 340.15  E-value: 2.40e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  17 RHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGREVQ 96
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  97 KLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDEAALG 176
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1604907081 177 REVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:TIGR00055 161 KHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 13-242 1.48e-108

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 313.74  E-value: 1.48e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  13 SSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLG 92
Cdd:PRK14830   20 GNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVEFLD 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  93 REVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDE 172
Cdd:PRK14830  100 KFVPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGKLNPEDITE 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 173 AALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:PRK14830  180 ELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQSRQRRFG 249
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 15-242 2.30e-102

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 297.63  E-value: 2.30e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  15 LPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGRE 94
Cdd:PRK14831   20 LPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFERVLRRE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  95 VQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDEAA 174
Cdd:PRK14831  100 LEELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDPSEIDENL 179

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1604907081 175 LGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:PRK14831  180 FESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFG 247
PRK14834 PRK14834
isoprenyl transferase;
5-242 1.95e-96

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 282.80  E-value: 1.95e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081   5 AALGDSAGSSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALM 84
Cdd:PRK14834    4 PAKDESDAMSVPRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLF 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  85 ELFMTVLGREVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGE 164
Cdd:PRK14834   84 GLLRLFIRRDLAELHRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREVAEGR 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1604907081 165 LDAEAVDEAALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:PRK14834  164 LDPASIDAETISANLDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYARRERRFG 241
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
13-242 1.85e-88

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 262.06  E-value: 1.85e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  13 SSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLG 92
Cdd:PRK14833    2 DNTLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKKYLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  93 REVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEaVDE 172
Cdd:PRK14833   82 DERSTYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKLLESPPSHIGELE-SLE 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 173 AALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:PRK14833  161 EEISNCLDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFG 230
PRK14838 PRK14838
isoprenyl transferase;
13-248 4.98e-85

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 253.64  E-value: 4.98e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  13 SSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLG 92
Cdd:PRK14838    8 NRIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLLDSIE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  93 REVqkLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDE 172
Cdd:PRK14838   88 EET--FMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELNPEEITE 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1604907081 173 AALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFGCTGEQI 248
Cdd:PRK14838  166 ESISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFGKTSEQI 241
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 15-254 1.55e-84

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 252.61  E-value: 1.55e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  15 LPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGRE 94
Cdd:PRK14832   18 IPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFERLLRRE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  95 VQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDEAA 174
Cdd:PRK14832   98 LAQMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADAVNEQL 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 175 LGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFGctgeQIRELIAA 254
Cdd:PRK14832  178 VEQHLYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDRRFG----QVKALIPA 253
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
18-242 1.57e-74

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 226.95  E-value: 1.57e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  18 HVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGREVQK 97
Cdd:PRK14839   12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLRAYLRNETER 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  98 LHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAArklARAVAAGELDAEAVDEAALGr 177
Cdd:PRK14839   92 LARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAA---AKALGPEGLSREAFSDLLTG- 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1604907081 178 evcmaDLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:PRK14839  168 -----DGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRFG 227
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 15-242 5.39e-72

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 222.52  E-value: 5.39e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  15 LPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGRE 94
Cdd:PRK14827   67 LPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVRRR 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  95 VQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDEAA 174
Cdd:PRK14827  147 RDNLNKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAGRLNPERITEST 226

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1604907081 175 LGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:PRK14827  227 IARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFG 294
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 14-242 9.23e-72

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 220.04  E-value: 9.23e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  14 SLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGR 93
Cdd:PRK14829   13 KLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRDVIHR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  94 EVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELDAEAVDEA 173
Cdd:PRK14829   93 RREQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIAREVRDGKISGDRVTEK 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1604907081 174 ALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:PRK14829  173 MISDHLYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFG 241
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 1-242 1.20e-69

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 214.71  E-value: 1.20e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081   1 MSLLAALGDSA---GSSLPRHVAIIMDGNGRWAQN----RGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENW 73
Cdd:PRK14840    1 MSLALEQAQENfpsLQSLPRHVAIIMDGNRRWYRKheqfCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  74 RRPEGEVNALMELFMTVLGREVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAA 153
Cdd:PRK14840   81 SRSKEEVAELFSLFNSQLDSQLPYLHENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 154 RKLARAVAAGELDAEAVDEAALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVAS 233
Cdd:PRK14840  161 KKLHQDLANKKISSDDISEELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKT 240


                  ....*....
gi 1604907081 234 FVARERRFG 242
Cdd:PRK14840  241 YQQRSRRGG 249
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 13-242 3.98e-67

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 207.92  E-value: 3.98e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  13 SSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLG 92
Cdd:PRK14842    6 STIPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSIFGLLVEFIE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  93 REVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARK--LARAVAAGELDaEAV 170
Cdd:PRK14842   86 TRLDTIHARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAQEvfLARKAKKVTLE-KPL 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1604907081 171 DEAALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:PRK14842  165 KEKEFEKFLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYETRTRKFG 236
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 15-246 2.47e-63

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 197.91  E-value: 2.47e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  15 LPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGRE 94
Cdd:PRK14841    3 IPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDRE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  95 VQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGEldAEAVDEAA 174
Cdd:PRK14841   83 MELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKDVSQGK--KIELTEET 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1604907081 175 LGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFGCTGE 246
Cdd:PRK14841  161 FRQYLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESYSKRERRFGGLIN 232
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 13-242 5.12e-62

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 194.66  E-value: 5.12e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  13 SSLPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLG 92
Cdd:PRK14837    4 NSLPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIADYLS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  93 REVQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKlaraVAAGELDAEAVDE 172
Cdd:PRK14837   84 SEFNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVKK----FLSSGLDLETLNE 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 173 AALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:PRK14837  160 NVFSKFLDNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKNRKRNFG 229
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 7-242 2.03e-52

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 170.70  E-value: 2.03e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081   7 LGDSAGSSLPRHVAIIMDGNGRWAQNRGKMRVS-GHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALME 85
Cdd:PRK14828   18 LGELDGAQVPGHVGIIVDGNRRWARKAGFTDVSqGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEELNPLLD 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  86 LFMTVLgREVQKlhENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKL-----ARAV 160
Cdd:PRK14828   98 IIEDVV-RQLAP--DGRWRVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLltehkDKGT 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 161 AAGELdAEAVDEAALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERR 240
Cdd:PRK14828  175 SIDEL-AESVTVDAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRALRDYSQRERR 253


                  ..
gi 1604907081 241 FG 242
Cdd:PRK14828  254 FG 255
PRK14835 PRK14835
isoprenyl transferase;
15-242 3.04e-52

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 171.18  E-value: 3.04e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  15 LPRHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMtvlgRE 94
Cdd:PRK14835   41 LPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVETLMNLFE----RE 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  95 VQKL------HENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGGQWDIAQAARKLARAVAAGELD-- 166
Cdd:PRK14835  117 ARRMavdpriHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLLLEAAATGKSpe 196

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1604907081 167 --AEAVDEAALGREVCMADLPPVDLLIRTGGDHRISNFVLWQLAYAELYFTPVLWPDFDEAEFSGAVASFVARERRFG 242
Cdd:PRK14835  197 evAAELTPEHISAHLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDYQGRERRFG 274
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 17-227 1.51e-22

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 94.29  E-value: 1.51e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  17 RHVAIIMDGNGRWAQNRGKMRVSGHKAGVKSVREAVSFAARAKMEALTLFAFSSENWRRPEGEVNALMELFMTVLGRE-- 94
Cdd:PTZ00349   21 KHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLFYLNLLILINEdf 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081  95 -VQKLHENGIRLKVIGDTSRFSERLQAKIAKAEALTADNRGLTLNIAANYGG-----------------------QWDIA 150
Cdd:PTZ00349  101 fFKFIKDNKIKIKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSrnemslckfnpnlyfdtyknlleEKKIL 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604907081 151 QAARKLARAVAAG----------------ELDAEAVD-------------EAALGRE----------VCMADLPPVDLLI 191
Cdd:PTZ00349  181 CGSNILTDPIKEGtfaipddedecdyldhELENERIDldlkfdgdcicgeKSFLNEEqieivnyhkkLLTSDLPPPNILI 260

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1604907081 192 RTGGDHRISNFVLWQLA-YAELYFTPVLWPDFDEAEF 227
Cdd:PTZ00349  261 RTSGEKRLSDFMLYQISeFTEIYFINEYWPIFNFLQF 297
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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