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Conserved domains on  [gi|1608687273|ref|WP_135313983|]
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FAD-binding oxidoreductase [Paracoccus liaowanqingii]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11429741)

FAD/NAD(P)-binding oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.30.9.10
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660
SCOP:  3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-344 3.23e-40

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


:

Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 145.05  E-value: 3.23e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273   1 MARVIhVAGAGIFGLSCAWMLARRGAGVRVFEARHIGAGASGGHVGALAPHAPDnwnPKKALQLQSLLAAPAFWAEVEDA 80
Cdd:COG0665     2 TADVV-VIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPGLAA---LADRALVRLAREALDLWRELAAE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273  81 AGLPSGYGRTGRLQPVPDAPTAERLQDRIAAAAQQ-WPRDMgmsLTRDPQAALIP-----DSPSGIWLQDAltARLNPRA 154
Cdd:COG0665    78 LGIDCDFRRTGVLYLARTEAELAALRAEAEALRALgLPVEL---LDAAELREREPglgspDYAGGLYDPDD--GHVDPAK 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 155 ALAALAAAIRARGGEILEARPAPDPTPDPAPDDAPT-----------IWATGtPGLQDLNAALDRRIG-QGVKGQSLLLA 222
Cdd:COG0665   153 LVRALARAARAAGVRIREGTPVTGLEREGGRVTGVRtergtvradavVLAAG-AWSARLLPMLGLRLPlRPVRGYVLVTE 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 223 --HAAPDSPQVFADGLHIVPHADGTTAIGSTSE-NSYDHDRPDHQARDLLARAIALCPALGQAPVLDIWAGLRPRARSRA 299
Cdd:COG0665   232 plPDLPLRPVLDDTGVYLRPTADGRLLVGGTAEpAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGL 311

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1608687273 300 PVLAPWPGRPGHLIANGGFKIGFGMAPLIADLAAQMLLDGRTDLP 344
Cdd:COG0665   312 PIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLD 356
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-344 3.23e-40

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 145.05  E-value: 3.23e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273   1 MARVIhVAGAGIFGLSCAWMLARRGAGVRVFEARHIGAGASGGHVGALAPHAPDnwnPKKALQLQSLLAAPAFWAEVEDA 80
Cdd:COG0665     2 TADVV-VIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPGLAA---LADRALVRLAREALDLWRELAAE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273  81 AGLPSGYGRTGRLQPVPDAPTAERLQDRIAAAAQQ-WPRDMgmsLTRDPQAALIP-----DSPSGIWLQDAltARLNPRA 154
Cdd:COG0665    78 LGIDCDFRRTGVLYLARTEAELAALRAEAEALRALgLPVEL---LDAAELREREPglgspDYAGGLYDPDD--GHVDPAK 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 155 ALAALAAAIRARGGEILEARPAPDPTPDPAPDDAPT-----------IWATGtPGLQDLNAALDRRIG-QGVKGQSLLLA 222
Cdd:COG0665   153 LVRALARAARAAGVRIREGTPVTGLEREGGRVTGVRtergtvradavVLAAG-AWSARLLPMLGLRLPlRPVRGYVLVTE 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 223 --HAAPDSPQVFADGLHIVPHADGTTAIGSTSE-NSYDHDRPDHQARDLLARAIALCPALGQAPVLDIWAGLRPRARSRA 299
Cdd:COG0665   232 plPDLPLRPVLDDTGVYLRPTADGRLLVGGTAEpAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGL 311

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1608687273 300 PVLAPWPGRPGHLIANGGFKIGFGMAPLIADLAAQMLLDGRTDLP 344
Cdd:COG0665   312 PIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLD 356
thiamin_ThiO TIGR02352
glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine ...
 19-339 4.38e-32

glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]


Pssm-ID: 274092 [Multi-domain]  Cd Length: 337  Bit Score: 122.86  E-value: 4.38e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273  19 WMLARRGAGVRVFEARHIGAGASGGHVGALAPHAPDNW--NPKKALQLQSLLAAPAFWAEVEDAAGLPSGYGRTGRLQPV 96
Cdd:TIGR02352   1 WELAKRGHSVTLFDRDPMGGGASWAAAGMLAPHAECEYaeDPLFDLALESLRLYPEWLEALKELTGLDTGYHQCGTLVVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273  97 PDAPTAERLQDRiaaaaQQWPRDMGMSLT-------RDPQAALIPDSPSGIWLQDalTARLNPRAALAALAAAIRARGGE 169
Cdd:TIGR02352  81 FDEDDVEHLRQL-----ADLQSATGMEVEwlsgralRRLEPYLSGGIRGAVFYPD--DAHVDPRALLKALEKALEKLGVE 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 170 ILEARPAPDPTPDPAPddaptiwATGTPGLQDLNAA----LDRRIGQG---------VKGQSLLLAHAAPDSPQ------ 230
Cdd:TIGR02352 154 IIEHTEVQHIEIRGEK-------VTAIVTPSGDVQAdqvvLAAGAWAGellplplrpVRGQPLRLEAPAVPLLNrplrav 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 231 VFADGLHIVPHADGTTAIGSTSENSYDHDRPDHQA-RDLLARAIALCPALGQAPVLDIWAGLRPRARSRAPVLAPWPGRP 309
Cdd:TIGR02352 227 VYGRRVYIVPRRDGRLVVGATMEESGFDTTPTLGGiKELLRDAYTILPALKEARLLETWAGLRPGTPDNLPYIGEHPEDR 306

                         330       340       350
                  ....*....|....*....|....*....|
gi 1608687273 310 GHLIANGGFKIGFGMAPLIADLAAQMLLDG 339
Cdd:TIGR02352 307 RLLIATGHYRNGILLAPATAEVIADLILGK 336
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 7-335 2.78e-28

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 112.49  E-value: 2.78e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273   7 VAGAGIFGLSCAWMLARRGAGVRVFEARH-IGAGASGGHVGALAPHAPDnwnPKKALQLQSLLAAPAFWAEVEDAAGLPS 85
Cdd:pfam01266   4 VIGGGIVGLSTAYELARRGLSVTLLERGDdPGSGASGRNAGLIHPGLRY---LEPSELARLALEALDLWEELEEELGIDC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273  86 GYGRTGRLqPVPDAPTAERLQDRIAAAAQQWPRDMGmsLTRDPQAALIPDSP---SGIWLQDAltARLNPRAALAALAAA 162
Cdd:pfam01266  81 GFRRCGVL-VLARDEEEEALEKLLAALRRLGVPAEL--LDAEELRELEPLLPglrGGLFYPDG--GHVDPARLLRALARA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 163 IRARGGEILE-------ARPAPDPTPDPAPDDAPTIWATGtPGLQDLNAALDRRIGQGVKGQSLLLAHAAPDSPQ----- 230
Cdd:pfam01266 156 AEALGVRIIEgtevtgiEEEGGVWGVVTTGEADAVVNAAG-AWADLLALPGLRLPVRPVRGQVLVLEPLPEALLIlpvpi 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 231 --VFADGLHIVPHADGTTAIGSTSENS-YDHDRPDHQARD-LLARAIALCPALgqAPVLDIWAGLRPrARSRAPVLAPwP 306
Cdd:pfam01266 235 tvDPGRGVYLRPRADGRLLLGGTDEEDgFDDPTPDPEEIEeLLEAARRLFPAL--ADIERAWAGLRP-LPDGLPIIGR-P 310

                         330       340
                  ....*....|....*....|....*....
gi 1608687273 307 GRPGHLIANGGFKIGFGMAPLIADLAAQM 335
Cdd:pfam01266 311 GSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 7-133 1.90e-05

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 46.38  E-value: 1.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273   7 VAGAGIFGLSCAWMLARRGAGVRVFEARH-IGAGASGGHVGALAPH--APDNwnpkkalqLQSLLAAPAF------WAEV 77
Cdd:PRK01747  265 IIGGGIAGAALALALARRGWQVTLYEADEaPAQGASGNRQGALYPLlsKDDN--------ALSRFFRAAFlfarrfYDAL 336

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1608687273  78 EdAAGLPSGYGRTGRLQPVPDAPTAERLQDriaAAAQQWPRDMGMSLTRDPQAALI 133
Cdd:PRK01747  337 P-AAGVAFDHDWCGVLQLAWDEKSAEKIAK---MLALGLPAELARALDAEEAEELA 388
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-344 3.23e-40

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 145.05  E-value: 3.23e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273   1 MARVIhVAGAGIFGLSCAWMLARRGAGVRVFEARHIGAGASGGHVGALAPHAPDnwnPKKALQLQSLLAAPAFWAEVEDA 80
Cdd:COG0665     2 TADVV-VIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPGLAA---LADRALVRLAREALDLWRELAAE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273  81 AGLPSGYGRTGRLQPVPDAPTAERLQDRIAAAAQQ-WPRDMgmsLTRDPQAALIP-----DSPSGIWLQDAltARLNPRA 154
Cdd:COG0665    78 LGIDCDFRRTGVLYLARTEAELAALRAEAEALRALgLPVEL---LDAAELREREPglgspDYAGGLYDPDD--GHVDPAK 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 155 ALAALAAAIRARGGEILEARPAPDPTPDPAPDDAPT-----------IWATGtPGLQDLNAALDRRIG-QGVKGQSLLLA 222
Cdd:COG0665   153 LVRALARAARAAGVRIREGTPVTGLEREGGRVTGVRtergtvradavVLAAG-AWSARLLPMLGLRLPlRPVRGYVLVTE 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 223 --HAAPDSPQVFADGLHIVPHADGTTAIGSTSE-NSYDHDRPDHQARDLLARAIALCPALGQAPVLDIWAGLRPRARSRA 299
Cdd:COG0665   232 plPDLPLRPVLDDTGVYLRPTADGRLLVGGTAEpAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGL 311

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1608687273 300 PVLAPWPGRPGHLIANGGFKIGFGMAPLIADLAAQMLLDGRTDLP 344
Cdd:COG0665   312 PIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLD 356
thiamin_ThiO TIGR02352
glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine ...
 19-339 4.38e-32

glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]


Pssm-ID: 274092 [Multi-domain]  Cd Length: 337  Bit Score: 122.86  E-value: 4.38e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273  19 WMLARRGAGVRVFEARHIGAGASGGHVGALAPHAPDNW--NPKKALQLQSLLAAPAFWAEVEDAAGLPSGYGRTGRLQPV 96
Cdd:TIGR02352   1 WELAKRGHSVTLFDRDPMGGGASWAAAGMLAPHAECEYaeDPLFDLALESLRLYPEWLEALKELTGLDTGYHQCGTLVVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273  97 PDAPTAERLQDRiaaaaQQWPRDMGMSLT-------RDPQAALIPDSPSGIWLQDalTARLNPRAALAALAAAIRARGGE 169
Cdd:TIGR02352  81 FDEDDVEHLRQL-----ADLQSATGMEVEwlsgralRRLEPYLSGGIRGAVFYPD--DAHVDPRALLKALEKALEKLGVE 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 170 ILEARPAPDPTPDPAPddaptiwATGTPGLQDLNAA----LDRRIGQG---------VKGQSLLLAHAAPDSPQ------ 230
Cdd:TIGR02352 154 IIEHTEVQHIEIRGEK-------VTAIVTPSGDVQAdqvvLAAGAWAGellplplrpVRGQPLRLEAPAVPLLNrplrav 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 231 VFADGLHIVPHADGTTAIGSTSENSYDHDRPDHQA-RDLLARAIALCPALGQAPVLDIWAGLRPRARSRAPVLAPWPGRP 309
Cdd:TIGR02352 227 VYGRRVYIVPRRDGRLVVGATMEESGFDTTPTLGGiKELLRDAYTILPALKEARLLETWAGLRPGTPDNLPYIGEHPEDR 306

                         330       340       350
                  ....*....|....*....|....*....|
gi 1608687273 310 GHLIANGGFKIGFGMAPLIADLAAQMLLDG 339
Cdd:TIGR02352 307 RLLIATGHYRNGILLAPATAEVIADLILGK 336
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 7-335 2.78e-28

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 112.49  E-value: 2.78e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273   7 VAGAGIFGLSCAWMLARRGAGVRVFEARH-IGAGASGGHVGALAPHAPDnwnPKKALQLQSLLAAPAFWAEVEDAAGLPS 85
Cdd:pfam01266   4 VIGGGIVGLSTAYELARRGLSVTLLERGDdPGSGASGRNAGLIHPGLRY---LEPSELARLALEALDLWEELEEELGIDC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273  86 GYGRTGRLqPVPDAPTAERLQDRIAAAAQQWPRDMGmsLTRDPQAALIPDSP---SGIWLQDAltARLNPRAALAALAAA 162
Cdd:pfam01266  81 GFRRCGVL-VLARDEEEEALEKLLAALRRLGVPAEL--LDAEELRELEPLLPglrGGLFYPDG--GHVDPARLLRALARA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 163 IRARGGEILE-------ARPAPDPTPDPAPDDAPTIWATGtPGLQDLNAALDRRIGQGVKGQSLLLAHAAPDSPQ----- 230
Cdd:pfam01266 156 AEALGVRIIEgtevtgiEEEGGVWGVVTTGEADAVVNAAG-AWADLLALPGLRLPVRPVRGQVLVLEPLPEALLIlpvpi 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273 231 --VFADGLHIVPHADGTTAIGSTSENS-YDHDRPDHQARD-LLARAIALCPALgqAPVLDIWAGLRPrARSRAPVLAPwP 306
Cdd:pfam01266 235 tvDPGRGVYLRPRADGRLLLGGTDEEDgFDDPTPDPEEIEeLLEAARRLFPAL--ADIERAWAGLRP-LPDGLPIIGR-P 310

                         330       340
                  ....*....|....*....|....*....
gi 1608687273 307 GRPGHLIANGGFKIGFGMAPLIADLAAQM 335
Cdd:pfam01266 311 GSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
7-69 3.39e-06

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 44.06  E-value: 3.39e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1608687273   7 VAGAGIFGLSCAWMLARRGAGVRVFEARHI--GAGASGGHVGALAPHAPDNWNPKKALQLQSLLA 69
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRlgGNAYSYRVPGYVFDYGAHIFHGSDEPNVRDLLD 65
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 7-133 1.90e-05

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 46.38  E-value: 1.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273   7 VAGAGIFGLSCAWMLARRGAGVRVFEARH-IGAGASGGHVGALAPH--APDNwnpkkalqLQSLLAAPAF------WAEV 77
Cdd:PRK01747  265 IIGGGIAGAALALALARRGWQVTLYEADEaPAQGASGNRQGALYPLlsKDDN--------ALSRFFRAAFlfarrfYDAL 336

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1608687273  78 EdAAGLPSGYGRTGRLQPVPDAPTAERLQDriaAAAQQWPRDMGMSLTRDPQAALI 133
Cdd:PRK01747  337 P-AAGVAFDHDWCGVLQLAWDEKSAEKIAK---MLALGLPAELARALDAEEAEELA 388
HpnW_proposed TIGR03364
FAD dependent oxidoreductase TIGR03364; This clade of FAD dependent oxidoreductases (members ...
 7-139 1.15e-04

FAD dependent oxidoreductase TIGR03364; This clade of FAD dependent oxidoreductases (members of the pfam01266 family) is syntenically associated with a family of proposed phosphonatase-like enzymes (TIGR03351) and is also found (less frequently) in association with phosphonate transporter components. A likely role for this enzyme involves the oxidative deamination of an aminophosphonate differring slightly from 2-aminoethylphosphonate, possibly 1-hydroxy-2-aminoethylphosphonate (see the comments for TIGR03351). Many members of the larger FAD dependent oxidoreductase family act as amino acid oxidative deaminases.


Pssm-ID: 132407 [Multi-domain]  Cd Length: 365  Bit Score: 43.44  E-value: 1.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1608687273   7 VAGAGIFGLSCAWMLARRGAGVRVFEARHIGAGAS---GGHVGALAPHAPDNWnpkkalqlQSLLAAPAFWAEVEDAAGL 83
Cdd:TIGR03364   5 IVGAGILGLAHAYAAARRGLSVTVIERSSRAQGASvrnFGQVWPTGQAPGPAW--------DRARRSREIWLELAAKAGI 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1608687273  84 PSgyGRTGRLQPVPDAPtAERLQDRIAAAAQQWPRDMGMsLTRDPQAALIPDSPSG 139
Cdd:TIGR03364  77 WV--RENGSLHLARTEE-ELAVLEEFAATREPAEYRVEL-LTPAEVAAKFPALRLD 128
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-34 4.87e-04

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 41.76  E-value: 4.87e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1608687273   1 MARVIHVAGAGIFGLSCAWMLARRGAGVRVFEAR 34
Cdd:COG3349     2 MPPRVVVVGGGLAGLAAAVELAEAGFRVTLLEAR 35
PRK07233 PRK07233
hypothetical protein; Provisional
 5-44 5.51e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 41.41  E-value: 5.51e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1608687273   5 IHVAGAGIFGLSCAWMLARRGAGVRVFEARHIGAGASGGH 44
Cdd:PRK07233    2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAASF 41
PRK05335 PRK05335
tRNA (uracil-5-)-methyltransferase Gid; Reviewed
 1-34 1.51e-03

tRNA (uracil-5-)-methyltransferase Gid; Reviewed


Pssm-ID: 235416  Cd Length: 436  Bit Score: 40.13  E-value: 1.51e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1608687273   1 MARVIHVAGAGIFGLSCAWMLARRGAGVRVFEAR 34
Cdd:PRK05335    1 MMKPVNVIGAGLAGSEAAWQLAKRGVPVELYEMR 34
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 6-35 1.54e-03

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 40.12  E-value: 1.54e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1608687273   6 HVA--GAGIFGLSCAWMLARRGAGVRVFEARH 35
Cdd:COG0493   123 KVAvvGSGPAGLAAAYQLARAGHEVTVFEALD 154
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 1-37 1.60e-03

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 40.20  E-value: 1.60e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1608687273   1 MARVIhVAGAGIFGLSCAWMLARRGAGVRVFEAR-HIG 37
Cdd:COG1232     1 MKRVA-VIGGGIAGLTAAYRLAKAGHEVTVLEASdRVG 37
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
1-34 2.60e-03

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 39.52  E-value: 2.60e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1608687273   1 MARVIhVAGAGIFGLSCAWMLARRGAGVRVFEAR 34
Cdd:COG1231     7 GKDVV-IVGAGLAGLAAARELRKAGLDVTVLEAR 39
PRK07538 PRK07538
hypothetical protein; Provisional
 7-52 3.43e-03

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 39.11  E-value: 3.43e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1608687273   7 VAGAGIFGLSCAWMLARRGAGVRVFEA----RHIGAGASgghvgaLAPHA 52
Cdd:PRK07538    5 IAGGGIGGLTLALTLHQRGIEVVVFEAapelRPLGVGIN------LLPHA 48
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 6-35 3.92e-03

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 39.01  E-value: 3.92e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1608687273   6 HVA--GAGIFGLSCAWMLARRGAGVRVFEARH 35
Cdd:PRK11749  142 KVAviGAGPAGLTAAHRLARKGYDVTIFEARD 173
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 7-34 4.32e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 38.70  E-value: 4.32e-03
                          10        20
                  ....*....|....*....|....*...
gi 1608687273   7 VAGAGIFGLSCAWMLARRGAGVRVFEAR 34
Cdd:PRK12771  142 VIGGGPAGLSAAYHLRRMGHAVTIFEAG 169
PRK07208 PRK07208
hypothetical protein; Provisional
 1-37 6.79e-03

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 38.33  E-value: 6.79e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1608687273   1 MARVIHVAGAGIFGLSCAWMLARRGAGVRVFEA-RHIG 37
Cdd:PRK07208    3 NKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEAdPVVG 40
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
1-44 9.72e-03

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 37.79  E-value: 9.72e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1608687273   1 MARV-IHVAGAGIFGLSCAWMLARRgAGVRVFEArhigAGASGGH 44
Cdd:COG2907     1 MARMrIAVIGSGISGLTAAWLLSRR-HDVTLFEA----NDRLGGH 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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