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Conserved domains on  [gi|1610866542|ref|WP_135442694|]
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tail fiber assembly protein, partial [Escherichia coli]

Protein Classification

tail fiber assembly protein( domain architecture ID 10493410)

tail fiber assembly protein is a chaperone involved in tail fiber assembly

Gene Ontology:  GO:0098004
PubMed:  31209305

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Caudo_TAP pfam02413
Caudovirales tail fibre assembly protein, lambda gpK; This family contains bacterial and phage ...
 72-189 1.85e-43

Caudovirales tail fibre assembly protein, lambda gpK; This family contains bacterial and phage tail fibre assembly proteins. E.coli contains several members of this family although the function of these proteins is uncertain. Using the lambda phage members as examples, there are both gptfa and gpK tail proteins here. GpK forms part of the TTC or tail-tip complex that is located at the distal end of the tail. TTCs form the platform on which the tail-tube proteins self-assemble and are also the attachment point for fibres or receptor-binding proteins that mediate phage-adsorption to the surface of the host cell. TTC assembly starts with gpJ, which is also known as the central tail fibre and is involved in host-cell adsorption. It is the C-terminus of gpJ that interacts with the lamB receptor on host cells. A number of intermediates including gpK then interact with gpJ during tail morphogenesis.


:

Pssm-ID: 426761  Cd Length: 130  Bit Score: 141.79  E-value: 1.85e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1610866542  72 RGKTVYEVASGDALFISEPGPLPENVTWLS---------PAGEYQKWDGVSWVKDEEAEKLFRIREAEEKKARLIQEATD 142
Cdd:pfam02413   1 RGQKLFSTDTLKPQYIAEGGILPESVTEVSdipenrripPPGKFDYWDGEGVPAWVTATKEEQIQQAEQEKQQLLAQASE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1610866542 143 NIAILQDAVNLEIATNEENSQLDSWRKYRVLVSRIDTSTAPDIVWPE 189
Cdd:pfam02413  81 QIAPLQDAVDLGIATDEEKAALLAWKKYRVLLNRVDTSLAPDIEWPE 127
 
Name Accession Description Interval E-value
Caudo_TAP pfam02413
Caudovirales tail fibre assembly protein, lambda gpK; This family contains bacterial and phage ...
 72-189 1.85e-43

Caudovirales tail fibre assembly protein, lambda gpK; This family contains bacterial and phage tail fibre assembly proteins. E.coli contains several members of this family although the function of these proteins is uncertain. Using the lambda phage members as examples, there are both gptfa and gpK tail proteins here. GpK forms part of the TTC or tail-tip complex that is located at the distal end of the tail. TTCs form the platform on which the tail-tube proteins self-assemble and are also the attachment point for fibres or receptor-binding proteins that mediate phage-adsorption to the surface of the host cell. TTC assembly starts with gpJ, which is also known as the central tail fibre and is involved in host-cell adsorption. It is the C-terminus of gpJ that interacts with the lamB receptor on host cells. A number of intermediates including gpK then interact with gpJ during tail morphogenesis.


Pssm-ID: 426761  Cd Length: 130  Bit Score: 141.79  E-value: 1.85e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1610866542  72 RGKTVYEVASGDALFISEPGPLPENVTWLS---------PAGEYQKWDGVSWVKDEEAEKLFRIREAEEKKARLIQEATD 142
Cdd:pfam02413   1 RGQKLFSTDTLKPQYIAEGGILPESVTEVSdipenrripPPGKFDYWDGEGVPAWVTATKEEQIQQAEQEKQQLLAQASE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1610866542 143 NIAILQDAVNLEIATNEENSQLDSWRKYRVLVSRIDTSTAPDIVWPE 189
Cdd:pfam02413  81 QIAPLQDAVDLGIATDEEKAALLAWKKYRVLLNRVDTSLAPDIEWPE 127
 
Name Accession Description Interval E-value
Caudo_TAP pfam02413
Caudovirales tail fibre assembly protein, lambda gpK; This family contains bacterial and phage ...
 72-189 1.85e-43

Caudovirales tail fibre assembly protein, lambda gpK; This family contains bacterial and phage tail fibre assembly proteins. E.coli contains several members of this family although the function of these proteins is uncertain. Using the lambda phage members as examples, there are both gptfa and gpK tail proteins here. GpK forms part of the TTC or tail-tip complex that is located at the distal end of the tail. TTCs form the platform on which the tail-tube proteins self-assemble and are also the attachment point for fibres or receptor-binding proteins that mediate phage-adsorption to the surface of the host cell. TTC assembly starts with gpJ, which is also known as the central tail fibre and is involved in host-cell adsorption. It is the C-terminus of gpJ that interacts with the lamB receptor on host cells. A number of intermediates including gpK then interact with gpJ during tail morphogenesis.


Pssm-ID: 426761  Cd Length: 130  Bit Score: 141.79  E-value: 1.85e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1610866542  72 RGKTVYEVASGDALFISEPGPLPENVTWLS---------PAGEYQKWDGVSWVKDEEAEKLFRIREAEEKKARLIQEATD 142
Cdd:pfam02413   1 RGQKLFSTDTLKPQYIAEGGILPESVTEVSdipenrripPPGKFDYWDGEGVPAWVTATKEEQIQQAEQEKQQLLAQASE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1610866542 143 NIAILQDAVNLEIATNEENSQLDSWRKYRVLVSRIDTSTAPDIVWPE 189
Cdd:pfam02413  81 QIAPLQDAVDLGIATDEEKAALLAWKKYRVLLNRVDTSLAPDIEWPE 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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