|
Name |
Accession |
Description |
Interval |
E-value |
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
1-544 |
0e+00 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 1019.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 1 MKKSALQKARAAYQPKLPIVLT---GAVKAVEGKATNSVADQEDIQKLFPNTYGLPEIHFEKGPAVKSAPINVGVILSGG 77
Cdd:PRK07085 1 MNKSYLQLARLKYRPKLPKLLQndpGLIKIVDGEFTESVADQDELAELFPNTYGLPYVTFVKGSESSSKPLKVGVILSGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 78 QAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFDIIGSGRTKLETKAQFDKGLEIL 157
Cdd:PRK07085 81 QAPGGHNVIAGLFDGLKKLNPDSKLFGFIGGPLGLLNGKYIEITEEVIDEYRNTGGFDMIGSGRTKIETEEQKEACLETV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 158 KKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQRDCNSSK 237
Cdd:PRK07085 161 KKLKLDGLVIIGGDDSNTNAAILAEYFAKHGCKTQVIGVPKTIDGDLKNEFIETSFGFDTATKTYSEMIGNISRDALSAK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 238 KYWHFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIEFIPAMK 317
Cdd:PRK07085 241 KYWHFIKLMGRSASHIALECALQTHPNICLISEEVAEKKMSLQDIVHYIASVIADRAAKGKNYGVILIPEGLIEFIPEMK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 318 ALIAELNDLLADNAEEFAKIDRQNQLSWIVDRLSSENASIFNSLPEGVARQLCLDRDPHGNVQVSLIETEKLLGEMVGRR 397
Cdd:PRK07085 321 SLIKELNSLLAENESEFKGLDTEAQREYIISKLSPESAKLFKSLPEDIARQLLLDRDPHGNVQVSKIETEKLLIEMVKKE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 398 LNEMKAEGRYVGKFASMFHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTKPSVQWTTGGIPITMM 477
Cdd:PRK07085 401 LEKLKPEGKYKGPFSAISHFFGYEGRSAFPSNFDADYCYALGYTAALLILNGKTGYMSTIKNLTSPYTEWIAGAVPLTMM 480
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1616153329 478 MNMERRHGAMKPVIQKALVKLDGAPFLKYAAQRDTWAINTDFIYPGPIQYFGPAEVCDQPSLTLRYE 544
Cdd:PRK07085 481 MNMERRHGKEKPVIKKALVDLDGPPFKYFAKYRDIWALEDSYRFPGPLQYFGPEELCDQRTLTLLLE 547
|
|
| PFKA_PPi |
TIGR02477 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Diphosphate--fructose-6-phosphate ... |
6-545 |
0e+00 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Diphosphate--fructose-6-phosphate 1-phosphotransferase catalyzes the addition of phosphate from diphosphate (PPi) to fructose 6-phosphate to give fructose 1,6-bisphosphate (EC 2.7.1.90). The enzyme is also known as pyrophosphate-dependent phosphofructokinase. The usage of PPi-dependent enzymes in glycolysis presumably frees up ATP for other processes. TIGR02482 represents the ATP-dependent 6-phosphofructokinase enzyme contained within pfam00365: Phosphofructokinase. This model hits primarily bacterial, plant alpha, and plant beta sequences. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 131530 [Multi-domain] Cd Length: 539 Bit Score: 922.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 6 LQKARAAYQPKLPIVLTGA---VKAVEGKATNSVADQEDIQKLFPNTYGLPEIHFEKGPAVK--SAPINVGVILSGGQAP 80
Cdd:TIGR02477 1 LQQSRLQYVPKLPKVLQGDtanISLEDGEPTAAVADQEELKELFPNTYGLPIITFEPGEASPdeHQPLKIGVILSGGQAP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 81 GGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFDIIGSGRTKLETKAQFDKGLEILKKL 160
Cdd:TIGR02477 81 GGHNVISGLFDALKKLNPNSKLYGFIGGPLGLLDNNYVELTKELIDTYRNTGGFDIIGSGRTKIETEEQFAKALTTAKKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 161 NIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQRDCNSSKKYW 240
Cdd:TIGR02477 161 KLDGLVIIGGDDSNTNAALLAEYFAKHGLKTQVIGVPKTIDGDLKNQFIETSFGFDTACKIYSELIGNICRDALSAKKYW 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 241 HFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIEFIPAMKALI 320
Cdd:TIGR02477 241 HFIRLMGRSASHIALECALQTHPNVCIIGEEVAAKKMTLSQLTDYIADVIVKRAAKGKNFGVILIPEGLIEFIPEVQALI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 321 AELNDLLADNAEEFAKIDrqnqlsWIVDRLSSENASIFNSLPEGVARQLCLDRDPHGNVQVSLIETEKLLGEMVGRRLNE 400
Cdd:TIGR02477 321 KELNNLLAQNVLEEGRKD------NVQSKLSPSSKALFESLPEFIRHQLLLDRDPHGNVQVSQIETEKLLIELVQTELNK 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 401 MKAEGRYVGKFASMFHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTKPSVQWTTGGIPITMMMNM 480
Cdd:TIGR02477 395 RKKEGEYKGKFSAVSHFFGYEGRCAFPSNFDSDYCYALGYTAAILLANGLTGYMSTIKNLTNPAEEWIAGGVPLTMMMNM 474
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1616153329 481 ERRHGAMKPVIQKALVKLDGAPFLKYAAQRDTWAINTDFIYPGPIQYFGPAEVCDQPSLTLRYEH 545
Cdd:TIGR02477 475 ERRHGEMKPVIKKALVDLEGKPFKKFASNRDKWALEDLYVFPGPIQYFGPEEVCDQPTLTLLLEQ 539
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
1-544 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 767.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 1 MKKSALQKARAAYQPKLPIVLTGA---VKAVEGKATNSVADQEDIQKLFPNTYGLPEIHFEKGPAVKSAP--INVGVILS 75
Cdd:cd00765 1 MVYSLVQQERINYTPKLPSVLKGDfnnIKIVEGPATSAAGDPDALAKLFPGTYGQPSVAFVPDQDAPSSApkLKIGIVLS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 76 GGQAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFDIIGSGRTKLETKAQFDKGLE 155
Cdd:cd00765 81 GGQAPGGHNVISGLFDYLKERAKGSTLYGFKGGPAGILKCDYIELNAEYIQPYRNTGGFDMICSGRTKIETEDQFKQAEE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 156 ILKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQRDCNS 235
Cdd:cd00765 161 TAKKLDLDALVVIGGDDSNTNAALLAENFRSKGLKTRVIGVPKTIDGDLKNKEIETSFGFDTATKIYSELIGNVMRDARS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 236 SKKYWHFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIEFIPA 315
Cdd:cd00765 241 TGKYWHFVKLMGRSASHIALECALKTHPNICIISEEVSAQKQTLKNITDYMVDVICKRAELGYNFGVVLVPEGLIEFIPE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 316 MKALIAELNDLLADNAEEFAKIDRQN-QLSWIVDRLSSENASIFNSLPEGVARQLCLDRDPHGNVQVSLIETEKLLGEMV 394
Cdd:cd00765 321 VKELIAELNEILANEVVEFNGLWKKKlTEQSLKLFDLLPKGVYLPLFIEAIQEQLMLERDPHGNVQVSRIETEKLLIQMV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 395 GRRLNEMKAEGRYVGKFASMFHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTKPSVQWTTGGIPI 474
Cdd:cd00765 401 ETRLEKMKQAGAYKGQFMGQSHFFGYEGRCAFPSNFDADYCYALGYGAGVLLNSGKTGYISSVGNLAAPVEEWTVGGVPL 480
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 475 TMMMNMERRHGAMKPVIQKALVKLDGAPFLKYAAQRDTWAINTDFIYPGPIQYFGPAEVCDQPSLTLRYE 544
Cdd:cd00765 481 TMLMNMERRHGKFKPVIKKALVDLEGAPFKKFASLREEWALKNRYIYPGPVQYTGPSEGSDELSHTLLLE 550
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
69-483 |
2.56e-73 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 236.90 E-value: 2.56e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 69 NVGVILSGGQAPGGHNVISGLfdgIKK-VNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFdIIGSGRTKL-ET 146
Cdd:COG0205 3 RIGILTSGGDAPGLNAAIRAV---VRTaIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGT-ILGSSRSKPfKT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 147 KAQFDKGLEILKKLNIKALVIIGGDDSNTNAAILAEYYksinaGVQVIGCPKTIDGDLKNemIETSFGFDTATKVYSEVI 226
Cdd:COG0205 79 EEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEY-----GIPVVGIPKTIDNDLPG--TDYTIGFDTAVNTAAEAI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 227 GNIQRDCNSSKKyWHFIKLMGRSASHIALECALQCQPNVCIISEEveakKETLNDivnsIADVVAARAANGNNFGSVLIP 306
Cdd:COG0205 152 DRLRDTAASHER-VFVVEVMGRHAGWLALAAGLAGGADLILIPEV----PFDLDK----LLEKLKERRKRGKGYSIIVVA 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 307 EGLIEFIPAMKALIaelndlladnaeefakidrqnqlswivdrlssenasifnslpegvarqlclDRDPHGNVQvsLIET 386
Cdd:COG0205 223 EGAGDEDGEAVLEA---------------------------------------------------DTDAFGHVR--LGGI 249
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 387 EKLLGEMVGRRLNemkAEGRYVgkfasmfhFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLtkpsvq 466
Cdd:COG0205 250 GEYLAKEIEERTG---IETRVT--------VLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRG------ 312
|
410
....*....|....*..
gi 1616153329 467 wTTGGIPITMMMNMERR 483
Cdd:COG0205 313 -EIVLVPLEEVANKEKP 328
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
69-308 |
1.30e-32 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 125.91 E-value: 1.30e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 69 NVGVILSGGQAPGGHNVI-----SGLFDGIKkvnrdsrLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGfDIIGSGRTK 143
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIravvrTAIYRGHE-------VYGIRNGYEGLVEGDIDELTWRDVSGILNRGG-TILGTSRSK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 144 L-ETKAQFDKGLEILKKLNIKALVIIGGDDSNTNAAILAEYYksinaGVQVIGCPKTIDGDLknEMIETSFGFDTATKVY 222
Cdd:pfam00365 73 PfKTEEGREKIAENLKKLGIDALVVIGGDGSLTGANKLSEER-----GIPVVGIPKTIDNDI--PGTDYTIGFDTALNTI 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 223 SEVIGNIqRDCNSSkkywH----FIKLMGRSASHIALECALQCQPNVCIISEEveakKETLNDIVNSIadvvaARAANGN 298
Cdd:pfam00365 146 VEAIDRI-RDTASS----HnrvfVVEVMGRHCGWLALMAGLAGGADAILIPEI----PFDIEELCEKI-----KELRKGK 211
|
250
....*....|
gi 1616153329 299 NFGSVLIPEG 308
Cdd:pfam00365 212 RFSIIVVAEG 221
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
1-544 |
0e+00 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 1019.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 1 MKKSALQKARAAYQPKLPIVLT---GAVKAVEGKATNSVADQEDIQKLFPNTYGLPEIHFEKGPAVKSAPINVGVILSGG 77
Cdd:PRK07085 1 MNKSYLQLARLKYRPKLPKLLQndpGLIKIVDGEFTESVADQDELAELFPNTYGLPYVTFVKGSESSSKPLKVGVILSGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 78 QAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFDIIGSGRTKLETKAQFDKGLEIL 157
Cdd:PRK07085 81 QAPGGHNVIAGLFDGLKKLNPDSKLFGFIGGPLGLLNGKYIEITEEVIDEYRNTGGFDMIGSGRTKIETEEQKEACLETV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 158 KKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQRDCNSSK 237
Cdd:PRK07085 161 KKLKLDGLVIIGGDDSNTNAAILAEYFAKHGCKTQVIGVPKTIDGDLKNEFIETSFGFDTATKTYSEMIGNISRDALSAK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 238 KYWHFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIEFIPAMK 317
Cdd:PRK07085 241 KYWHFIKLMGRSASHIALECALQTHPNICLISEEVAEKKMSLQDIVHYIASVIADRAAKGKNYGVILIPEGLIEFIPEMK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 318 ALIAELNDLLADNAEEFAKIDRQNQLSWIVDRLSSENASIFNSLPEGVARQLCLDRDPHGNVQVSLIETEKLLGEMVGRR 397
Cdd:PRK07085 321 SLIKELNSLLAENESEFKGLDTEAQREYIISKLSPESAKLFKSLPEDIARQLLLDRDPHGNVQVSKIETEKLLIEMVKKE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 398 LNEMKAEGRYVGKFASMFHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTKPSVQWTTGGIPITMM 477
Cdd:PRK07085 401 LEKLKPEGKYKGPFSAISHFFGYEGRSAFPSNFDADYCYALGYTAALLILNGKTGYMSTIKNLTSPYTEWIAGAVPLTMM 480
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1616153329 478 MNMERRHGAMKPVIQKALVKLDGAPFLKYAAQRDTWAINTDFIYPGPIQYFGPAEVCDQPSLTLRYE 544
Cdd:PRK07085 481 MNMERRHGKEKPVIKKALVDLDGPPFKYFAKYRDIWALEDSYRFPGPLQYFGPEELCDQRTLTLLLE 547
|
|
| PFKA_PPi |
TIGR02477 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Diphosphate--fructose-6-phosphate ... |
6-545 |
0e+00 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Diphosphate--fructose-6-phosphate 1-phosphotransferase catalyzes the addition of phosphate from diphosphate (PPi) to fructose 6-phosphate to give fructose 1,6-bisphosphate (EC 2.7.1.90). The enzyme is also known as pyrophosphate-dependent phosphofructokinase. The usage of PPi-dependent enzymes in glycolysis presumably frees up ATP for other processes. TIGR02482 represents the ATP-dependent 6-phosphofructokinase enzyme contained within pfam00365: Phosphofructokinase. This model hits primarily bacterial, plant alpha, and plant beta sequences. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 131530 [Multi-domain] Cd Length: 539 Bit Score: 922.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 6 LQKARAAYQPKLPIVLTGA---VKAVEGKATNSVADQEDIQKLFPNTYGLPEIHFEKGPAVK--SAPINVGVILSGGQAP 80
Cdd:TIGR02477 1 LQQSRLQYVPKLPKVLQGDtanISLEDGEPTAAVADQEELKELFPNTYGLPIITFEPGEASPdeHQPLKIGVILSGGQAP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 81 GGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFDIIGSGRTKLETKAQFDKGLEILKKL 160
Cdd:TIGR02477 81 GGHNVISGLFDALKKLNPNSKLYGFIGGPLGLLDNNYVELTKELIDTYRNTGGFDIIGSGRTKIETEEQFAKALTTAKKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 161 NIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQRDCNSSKKYW 240
Cdd:TIGR02477 161 KLDGLVIIGGDDSNTNAALLAEYFAKHGLKTQVIGVPKTIDGDLKNQFIETSFGFDTACKIYSELIGNICRDALSAKKYW 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 241 HFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIEFIPAMKALI 320
Cdd:TIGR02477 241 HFIRLMGRSASHIALECALQTHPNVCIIGEEVAAKKMTLSQLTDYIADVIVKRAAKGKNFGVILIPEGLIEFIPEVQALI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 321 AELNDLLADNAEEFAKIDrqnqlsWIVDRLSSENASIFNSLPEGVARQLCLDRDPHGNVQVSLIETEKLLGEMVGRRLNE 400
Cdd:TIGR02477 321 KELNNLLAQNVLEEGRKD------NVQSKLSPSSKALFESLPEFIRHQLLLDRDPHGNVQVSQIETEKLLIELVQTELNK 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 401 MKAEGRYVGKFASMFHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTKPSVQWTTGGIPITMMMNM 480
Cdd:TIGR02477 395 RKKEGEYKGKFSAVSHFFGYEGRCAFPSNFDSDYCYALGYTAAILLANGLTGYMSTIKNLTNPAEEWIAGGVPLTMMMNM 474
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1616153329 481 ERRHGAMKPVIQKALVKLDGAPFLKYAAQRDTWAINTDFIYPGPIQYFGPAEVCDQPSLTLRYEH 545
Cdd:TIGR02477 475 ERRHGEMKPVIKKALVDLEGKPFKKFASNRDKWALEDLYVFPGPIQYFGPEEVCDQPTLTLLLEQ 539
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
1-544 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 767.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 1 MKKSALQKARAAYQPKLPIVLTGA---VKAVEGKATNSVADQEDIQKLFPNTYGLPEIHFEKGPAVKSAP--INVGVILS 75
Cdd:cd00765 1 MVYSLVQQERINYTPKLPSVLKGDfnnIKIVEGPATSAAGDPDALAKLFPGTYGQPSVAFVPDQDAPSSApkLKIGIVLS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 76 GGQAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFDIIGSGRTKLETKAQFDKGLE 155
Cdd:cd00765 81 GGQAPGGHNVISGLFDYLKERAKGSTLYGFKGGPAGILKCDYIELNAEYIQPYRNTGGFDMICSGRTKIETEDQFKQAEE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 156 ILKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQRDCNS 235
Cdd:cd00765 161 TAKKLDLDALVVIGGDDSNTNAALLAENFRSKGLKTRVIGVPKTIDGDLKNKEIETSFGFDTATKIYSELIGNVMRDARS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 236 SKKYWHFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIEFIPA 315
Cdd:cd00765 241 TGKYWHFVKLMGRSASHIALECALKTHPNICIISEEVSAQKQTLKNITDYMVDVICKRAELGYNFGVVLVPEGLIEFIPE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 316 MKALIAELNDLLADNAEEFAKIDRQN-QLSWIVDRLSSENASIFNSLPEGVARQLCLDRDPHGNVQVSLIETEKLLGEMV 394
Cdd:cd00765 321 VKELIAELNEILANEVVEFNGLWKKKlTEQSLKLFDLLPKGVYLPLFIEAIQEQLMLERDPHGNVQVSRIETEKLLIQMV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 395 GRRLNEMKAEGRYVGKFASMFHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTKPSVQWTTGGIPI 474
Cdd:cd00765 401 ETRLEKMKQAGAYKGQFMGQSHFFGYEGRCAFPSNFDADYCYALGYGAGVLLNSGKTGYISSVGNLAAPVEEWTVGGVPL 480
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 475 TMMMNMERRHGAMKPVIQKALVKLDGAPFLKYAAQRDTWAINTDFIYPGPIQYFGPAEVCDQPSLTLRYE 544
Cdd:cd00765 481 TMLMNMERRHGKFKPVIKKALVDLEGAPFKKFASLREEWALKNRYIYPGPVQYTGPSEGSDELSHTLLLE 550
|
|
| PLN02251 |
PLN02251 |
pyrophosphate-dependent phosphofructokinase |
4-544 |
0e+00 |
|
pyrophosphate-dependent phosphofructokinase
Pssm-ID: 215140 Cd Length: 568 Bit Score: 668.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 4 SALQKARAAYQPKLPIVLTGAVKAVEGKATNSVADQEDIQKLFPNTYGLPEIHF--EKGPAVKSA-PINVGVILSGGQAP 80
Cdd:PLN02251 30 SEVQSSRIDHALPLPSVLKGPFKIVDGPPSSAAGNPEEIAKLFPNLFGQPSVMLvpSQADALSSDqKLKIGVVLSGGQAP 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 81 GGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFDIIGSGRTKLETKAQFDKGLEILKKL 160
Cdd:PLN02251 110 GGHNVISGIFDYLQEHAKGSVLYGFKGGPAGIMKCKYVELTAEFIYPYRNQGGFDMICSGRDKIETPEQFKQAEETATKL 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 161 NIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQRDCNSSKKYW 240
Cdd:PLN02251 190 DLDGLVVIGGDDSNTNACLLAEYFRAKNLKTRVIGCPKTIDGDLKSKEVPTSFGFDTACKIYSEMIGNVMIDARSTGKYY 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 241 HFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIEFIPAMKALI 320
Cdd:PLN02251 270 HFVRLMGRAASHITLECALQTHPNITIIGEEVAAKKLTLKNVTDYIVDVICKRAELGYNYGVILIPEGLIDFIPEVQHLI 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 321 AELNDLLADNAeefakIDRQNQlsWiVDRLSSENASIFNSLPEGVARQLCLDRDPHGNVQVSLIETEKLLGEMVGRRLNE 400
Cdd:PLN02251 350 AELNEILAHDV-----VDEEGH--W-KKKLKPQSLQLFDFLPHAIQEQLMLERDPHGNVQVAKIETEKMLIQMVETELEK 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 401 MKAEGRYVGKFASMFHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTKPSVQWTTGGIPITMMMNM 480
Cdd:PLN02251 422 RKQEGSYKGHFKGQSHFFGYEGRCGLPTNFDATYCYALGYGAGALLHSGKTGLISSVGNLAAPVEEWTVGGTALTSLMDV 501
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1616153329 481 ERRHGAMKPVIQKALVKLDGAPFLKYAAQRDTWAINTDFIYPGPIQYFGPAEvcDQPSLTLRYE 544
Cdd:PLN02251 502 ERRHGKFKPVIKKAMVELEGAPFKKFASLRDEWALKNRYISPGPIQFSGPGS--DATNHTLKLE 563
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
4-530 |
2.25e-174 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 527.62 E-value: 2.25e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 4 SALQKARAAYQPKLPIVLTGAVKAVEGKATNSVADQE--DIQKLFPNTYGLPEIHFE----------KGPAVKsapinVG 71
Cdd:PTZ00468 32 SNMQMWRRRWEPCLPHILRSPLSIKEVSAFEGMGKMErsDVSSYFPLTSGNSLVKFEaisdgssswkKFPARR-----IG 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 72 VILSGGQAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFDIIGSGRTKLETKAQFD 151
Cdd:PTZ00468 107 VVLSGGQASGGHNVIAGLMSYIKLCNQSSQLFGFLGGPEGVYSERYRELTEDDINGILNQGGFNIICSGRHKIETEEQMR 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 152 KGLEILKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQR 231
Cdd:PTZ00468 187 ASLEICEKLKLHGLVVIGGDDSNTNAAVLAEYFKRNSSSTVVVGCPKTIDGDLKNEVIETSFGYDTAVKTYSEQIGSIMD 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 232 DCNSSKKYWHFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIE 311
Cdd:PTZ00468 267 AIKTEGYGYYFVRLMGRSASHITLECGLQTRANMILIGEEIKEENRSLMSIVDEIVEMILKRDSLGKKHGIVLLPEGLIE 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 312 FIPAMKALIAELND-LLADNaeefakiDRQNqlswIVDRLSSENASIFNSLPEGVARQLCLDRDPHGNVQVSLIETEKLL 390
Cdd:PTZ00468 347 FIPEFETLIKELNLiLLKTN-------DRKQ----IIDSLSQEMKTLFLELPSDVQNQLLLERDPHGNVQVAKIATEELL 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 391 GEMVGRRLNEMKAEgrYVGKFASMfHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTKPSVQWTTG 470
Cdd:PTZ00468 416 VHMAKEKLEEVKKD--YILDNVKT-HYFGYEGRCALPSNFDASYCFALGHTAAALIDNQRSGYMAVVRKLSLTPEQWEPA 492
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 471 GIPITMMMNMERRHGAMKPVIQKALVKLDGAPFLKYAAQRDTWAINTDFIYPGPIQYFGP 530
Cdd:PTZ00468 493 GCPLTYMMNIELRKGKSVPVIKKYLVDLKGQSYLAYCQVRSEWKLNDYYRNPGPIQFDGP 552
|
|
| PLN03028 |
PLN03028 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
4-544 |
5.48e-165 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 215543 Cd Length: 610 Bit Score: 481.97 E-value: 5.48e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 4 SALQKARAAYQPKLPIVLTGA-VKAVEGKATNSV--ADQEDIQKLFPNTYGLPEIHFEKGPAV--------KSAPINVGV 72
Cdd:PLN03028 5 SGLQKLRSLYQPELPPCLQGTtVRVELGDATTAAdpADAHAISRAFPHTYGQPLAHFLRATAKvpdaqvitEHPAVRVGV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 73 ILSGGQAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFDIIGSGRTKLETKAQFDK 152
Cdd:PLN03028 85 VFCGRQSPGGHNVIWGLHDALKAHNPNSVLLGFLGGTEGLFAQKTLEITDDVLSTYKNQGGYDLLGRTKDQIRTTEQVNA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 153 GLEILKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQRD 232
Cdd:PLN03028 165 ALAACEALKLDGLVIIGGVTSNTDAAQLAETFAEAKCKTKVVGVPVTLNGDLKNQFVETNVGFDTICKVNSQLISNVCTD 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 233 CNSSKKYWHFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIEF 312
Cdd:PLN03028 245 ALSAEKYYYFIRLMGRKASHVALECALQSHPNMVILGEEVAASKLTLFDITKQICDAVQARAEQDKNHGVILIPEGLIES 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 313 IPAMKALIAELNDLLADNaeefakIDRQNqlswIVDRLSSENASIFNSLPEGVARQLCLDRDPHGNVQVSLIETEKLLGE 392
Cdd:PLN03028 325 IPEVYALLQEIHGLLKQG------VSVDN----ISSQLSPWASALFEFLPPFIKKQLLLHPESDDSAQLSQIETEKLLAQ 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 393 MVGRRLNEMKAEGRYVG-KFASMFHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTKPSVQWTTGG 471
Cdd:PLN03028 395 LVETEMNKRTKEGTYKGkKFNAICHFFGYQARGSLPSKFDCDYAYVLGHICYHILAAGLNGYMATVTNLKSPVNKWRCGA 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 472 IPITMMMNMERRH---GAM---KPVIQKALVKLDGAPF--LKYAAQRdtWAINTDFIYPGPIQYFGPAevCDQPSLTLRY 543
Cdd:PLN03028 475 APITAMMSVKRWSrgpGASqigKPAIHPAPVDLKGKAYelLRQNASS--FLMDDLYRNPGPLQFDGPG--ADAKPITLCV 550
|
.
gi 1616153329 544 E 544
Cdd:PLN03028 551 E 551
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
4-529 |
1.43e-141 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 443.33 E-value: 1.43e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 4 SALQKARAAYQPKLPIVLTGAVKAVE---GKATNSVADQEDIQKLFPNTYGLPEIH---------FEKGPAVKsapinVG 71
Cdd:PTZ00287 107 SPLQYERIKYQPTLPKALASEYQILEenhGDDFINKKDYEEVKRFLKNLHNLPILNvketnnhesFKGGNVLK-----IG 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 72 VILSGGQAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFDIIGSGRTKLETKAQFD 151
Cdd:PTZ00287 182 IILSGGPAPGGHNVISGIYDYAKRYNEQSQVIGFLGGIDGLYSKNYVTITDSLMNRFRNLGGFNMLWSGRGKVRNKDDLI 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 152 KGLEILKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQR 231
Cdd:PTZ00287 262 AIENIVAKLKLNGLVIIGGDGSNSNAALISEYFAERQIPISIIGIPKTIDGDLKSEAIEISFGFDTATKTYSEVIGNLCT 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 232 DCNSSKKYWHFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIE 311
Cdd:PTZ00287 342 DVKTGHNVYHVVRVMGRSASHVVLECALQTRPNIVLIGEEVEKENLSLKDIVSNIVNTILKRRSLNKNYGVILIPEGLIE 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 312 FIPAMKALIAELNDLLADNAEEFAKIDRQNQlswivdrlssenasIFNSLPEGVARQLCLDRDPHGNVQVSLIETEKLLG 391
Cdd:PTZ00287 422 FVPEMKILIGELNVILKEGPFDASKLKHSRE--------------VWDFLPSIIRDQLLMDRESTGYIQVGKIATERLII 487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 392 EMVGRRLNEMKAEGRYVgKFasMFHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTKPSVQWTTGG 471
Cdd:PTZ00287 488 VLVESELAKLNDNNLNI-QF--MAHYLGYEGRCAIPSNFDCNYCYALGYNAALLIDHKKTGYMSIIQNLEDSYANWIPAA 564
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 1616153329 472 IPITMMMNMERRH-GAMKPVIQKALVKLDGAPFLKYAAQRDTWAINTDFIYPGPIQYFG 529
Cdd:PTZ00287 565 IPFLRIMHVNRDNtGKEFPAVKRYLVDLNSPLFNVLKEVRSLWSLYDLYRSPGPIQFNG 623
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
69-507 |
2.81e-118 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 352.76 E-value: 2.81e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 69 NVGVILSGGQAPGGHNVISGLFDGIKKVNrdSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFdIIGSGRTK-LETK 147
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAIAEG--LEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGT-IIGSARCKeFRTE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 148 AQFDKGLEILKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNemIETSFGFDTATKVYSEVIG 227
Cdd:cd00363 79 EGRAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEWPSKYQGFNVIGLPGTIDNDIKG--TDYTIGFDTALKTIVEAID 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 228 NIqRDCNSSKKYWHFIKLMGRSASHIALECALQCQPNVCIISEEVEAKketlnDIVNSIADVVAARAANGNNFGSVLIPE 307
Cdd:cd00363 157 RI-RDTASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAAD-----EWEEEMVDVIKKRRERGKRHGIVIVAE 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 308 GLIEFIPAmkaliaelndlladnaeefakidrqnqlswivdrlssenasifnslpegvarqlcldrdphgnvqvslIETE 387
Cdd:cd00363 231 GAIDFIPK--------------------------------------------------------------------PITE 242
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 388 KLLGEMVGRRLnemkaegryvgKFASMFHFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLTkpsvQW 467
Cdd:cd00363 243 KLLAKLVEERL-----------GFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGTPVGIQNLN----EN 307
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1616153329 468 TTGGIPITMMMNMERRHGamkpviqkalVKLDGAPFLKYA 507
Cdd:cd00363 308 QVVRHPLTEAVNMTKRVG----------VDLEGRPFKKFA 337
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
4-531 |
2.86e-100 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 330.85 E-value: 2.86e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 4 SALQKARAAYQPKLPIV---LTGAVKAVEGKATNSVADQEDIQKLFP-----NTYGLPEIHFEKGPAVKSAPINVGVILS 75
Cdd:PTZ00287 765 SELQTSRLYNKLELPELcsdLKAKVRAGKQYISNDPYTQKQILSNYPhmsyeNKFQIQEIFHDKYATPISFEIKIGIVFL 844
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 76 GGQAPGGHNVISGLFDGIKKVNRDS-RLYGFLmgpgGFVDHKYMELTASYIDEYRNTGGFDIIG-SGRTKLETKAQFDKG 153
Cdd:PTZ00287 845 SRQAPGAMNVLCGLYRRLKLLKGVCiAFYGLY----GLLNNKYIIIDDDNIAKHVNQGGLELTGnSPEHSLFDKENRNKV 920
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 154 LEILKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQRDC 233
Cdd:PTZ00287 921 CETVTNLQLNGLVMPGSNVTITEAALLAEYFLEKKIPTSVVGIPLTGSNNLIHELIETCVGFDSSTKVYASLIGNVLTDA 1000
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 234 NSSKKYWHFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIEFI 313
Cdd:PTZ00287 1001 VSMPKYWHFIRLMGRSPSHEVLECALQTHPNMVIISEEYGAADKTLWRVVQDIADVVCARAELGKNYGTVLIPDALLMHL 1080
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 314 PAMKALIAELNDLLADNAEEFAKIDRQNQL----------------------------SWiVDRLSSENASIFNSLPEGV 365
Cdd:PTZ00287 1081 PHMKILLSEISDILNDANEKGQLVEARNDLvnlsttqhghlgstagtvagaeqplsasPW-VSKLTPWSLALLKTFPQFI 1159
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 366 ARQLcLDRDPHgNVQVSLIETEKLLGEMVGRRLNEMKAEGRYVGKFASMFHFFGYEGRCADPSNFDADYCYALGFNAACL 445
Cdd:PTZ00287 1160 IKEL-LHVDLR-SMRFEKLETEQLLLQMVKEELHQRKQKGKYSGSFMGLTHFFGYQGRSSLPSEFDCKLAYSYGHAASIV 1237
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 446 INAGVTGYMSSVRGLTKPSVQWTTGGIP-ITMMMNMERRHGA--MK-------PVIQKALVKLDGAPF--LKYAAQRdtW 513
Cdd:PTZ00287 1238 IESGLTGYIVSIRGLCGNIKDWKLFAIPfISLMKILPRGQGSkyLKsaskgdlPVIPSAPVDLNGKAYrsLKIALQK--W 1315
|
570
....*....|....*...
gi 1616153329 514 AINTDFIYPGPIQYFGPA 531
Cdd:PTZ00287 1316 QMEDRFCNPGPIQFEGNA 1333
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
69-483 |
2.56e-73 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 236.90 E-value: 2.56e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 69 NVGVILSGGQAPGGHNVISGLfdgIKK-VNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGFdIIGSGRTKL-ET 146
Cdd:COG0205 3 RIGILTSGGDAPGLNAAIRAV---VRTaIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGT-ILGSSRSKPfKT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 147 KAQFDKGLEILKKLNIKALVIIGGDDSNTNAAILAEYYksinaGVQVIGCPKTIDGDLKNemIETSFGFDTATKVYSEVI 226
Cdd:COG0205 79 EEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEY-----GIPVVGIPKTIDNDLPG--TDYTIGFDTAVNTAAEAI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 227 GNIQRDCNSSKKyWHFIKLMGRSASHIALECALQCQPNVCIISEEveakKETLNDivnsIADVVAARAANGNNFGSVLIP 306
Cdd:COG0205 152 DRLRDTAASHER-VFVVEVMGRHAGWLALAAGLAGGADLILIPEV----PFDLDK----LLEKLKERRKRGKGYSIIVVA 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 307 EGLIEFIPAMKALIaelndlladnaeefakidrqnqlswivdrlssenasifnslpegvarqlclDRDPHGNVQvsLIET 386
Cdd:COG0205 223 EGAGDEDGEAVLEA---------------------------------------------------DTDAFGHVR--LGGI 249
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 387 EKLLGEMVGRRLNemkAEGRYVgkfasmfhFFGYEGRCADPSNFDADYCYALGFNAACLINAGVTGYMSSVRGLtkpsvq 466
Cdd:COG0205 250 GEYLAKEIEERTG---IETRVT--------VLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRG------ 312
|
410
....*....|....*..
gi 1616153329 467 wTTGGIPITMMMNMERR 483
Cdd:COG0205 313 -EIVLVPLEEVANKEKP 328
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
71-529 |
1.56e-51 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 190.19 E-value: 1.56e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 71 GVILSGGQAPGGHNVISGLFDGIKKVNRD---SRLYGFLMGPGGFVDHKyMELTASYIDEYRNTGGFDIIGSGRTKLET- 146
Cdd:PTZ00468 679 GLILSCLSTPGTQNVICGLVNGLPSLKQLivfKSLSDFYEGKALKVDLT-SEGSLEFFENSLNSGGCIFPNGVEIKMNVs 757
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 147 ---------KAQFDKGL-------------------EILKKLNIKALVIIGGDDSNTNAAILAEY-----YKSINAGVQV 193
Cdd:PTZ00468 758 ekkysnttlKANDNQEFtnsscvlsckglvsndflsQLLSFFNMRAIAIVGNSEAATFGASLSEQlicmsLNGMKSEIPV 837
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 194 IGCPKTIDGDLKNEMIETSFGFDTATKVYSEVIGNIQRDCNSSKKYWHFIKLMGRSASHIALECALQCQPNVCIISE--- 270
Cdd:PTZ00468 838 VFVPVCLENSISHQMIETCIGFDSVTKSISTLVGNLLTDSASATKYWYFMKMIGDKTSNVALEVGIQTHPNLVVIPErya 917
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 271 -------EVEAKKETLNDIVNSIADVVAARAANGNNFGSVLIPEGLIEFIPAMKA---LIAELN--DLLADNAEEFAKID 338
Cdd:PTZ00468 918 dsklsvyGSEMAGVTLDDIITEICDIICLRSNQGNNFGGLLVSEGLFDQVYPTREyrkIFSRFStqNLCNASNSGNCEIL 997
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 339 RQNQLSWIVDRLSSENASIFNSLPEGVARQLCLDRdphgnvQVSLIETEKLLGEMVGRRLNEMKAEGRYVGKFASMFHFF 418
Cdd:PTZ00468 998 GSESLSRYEKKVVEDFKLIFSDIDERLIENLINSR------KICDVRTEIILSALVQKELKFRRSKNKIKNGMNPVCFSF 1071
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 419 GYEGRCADPSNFDADYCYALGFNAACLINAG-VTGYMSSVRGLTKPSVQWTTGGIPIT--MMMNME-------RRHGAMK 488
Cdd:PTZ00468 1072 TDQVRACIPSDFDSTLGLMYGMLASKIINSNlVGGYVTGIKGVLSQIDSWNMYAIPISslMTLNIEgdkimdsRNNSNLS 1151
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1616153329 489 PVIQKALVK---------------------LDGAPFLKYAAQRDTWAINTDFIYPGPIQYFG 529
Cdd:PTZ00468 1152 FESKKLLTEstlgnaghqleficklnsvnmRNNPSFKLLMNHIEKWEVDNTYANPGPIQYFN 1213
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
69-308 |
1.30e-32 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 125.91 E-value: 1.30e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 69 NVGVILSGGQAPGGHNVI-----SGLFDGIKkvnrdsrLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGfDIIGSGRTK 143
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIravvrTAIYRGHE-------VYGIRNGYEGLVEGDIDELTWRDVSGILNRGG-TILGTSRSK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 144 L-ETKAQFDKGLEILKKLNIKALVIIGGDDSNTNAAILAEYYksinaGVQVIGCPKTIDGDLknEMIETSFGFDTATKVY 222
Cdd:pfam00365 73 PfKTEEGREKIAENLKKLGIDALVVIGGDGSLTGANKLSEER-----GIPVVGIPKTIDNDI--PGTDYTIGFDTALNTI 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 223 SEVIGNIqRDCNSSkkywH----FIKLMGRSASHIALECALQCQPNVCIISEEveakKETLNDIVNSIadvvaARAANGN 298
Cdd:pfam00365 146 VEAIDRI-RDTASS----HnrvfVVEVMGRHCGWLALMAGLAGGADAILIPEI----PFDIEELCEKI-----KELRKGK 211
|
250
....*....|
gi 1616153329 299 NFGSVLIPEG 308
Cdd:pfam00365 212 RFSIIVVAEG 221
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
70-308 |
3.83e-31 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 123.27 E-value: 3.83e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 70 VGVILSGGQAPGGHNVISGLfdgIKK-VNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGfDIIGSGRTK-LETK 147
Cdd:PRK03202 4 IGVLTSGGDAPGMNAAIRAV---VRTaISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGG-TILGSARFPeFKDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 148 AQFDKGLEILKKLNIKALVIIGGDDSNTNAAILAEYyksinaGVQVIGCPKTIDGDLKneMIETSFGFDTATKVYSEVIG 227
Cdd:PRK03202 80 EGRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEH------GIPVIGLPGTIDNDIA--GTDYTIGFDTALNTAVEAID 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 228 NIqRDCNSSkkywH----FIKLMGRSASHIALECALQCQPNVCIISEEveakKETLNDIVNSIADvvaaRAANGNNFGSV 303
Cdd:PRK03202 152 RL-RDTASS----HervfIVEVMGRHAGDLALHAGIAGGAEVILIPEV----PFDIEELCAKIKK----GRERGKKHAII 218
|
....*
gi 1616153329 304 LIPEG 308
Cdd:PRK03202 219 VVAEG 223
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
70-270 |
9.68e-24 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 103.97 E-value: 9.68e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 70 VGVILSGGQAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGfDIIGSGRTKLETkaq 149
Cdd:PTZ00286 90 AGIVTCGGLCPGLNVVIRELVMNLINNYGVKTIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGG-TILGSSRGGFDP--- 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 150 fDKGLEILKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKneMIETSFGFDTATKVYSEVIGNI 229
Cdd:PTZ00286 166 -KVMVDTLIRHGINILFTLGGDGTHRGALAIYKELRRRKLNISVVGIPKTIDNDIP--IIDESFGFQTAVEEAQNAIRAA 242
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1616153329 230 QRDCNSSKKYWHFIKLMGRSASHIALECALQC-QPNVCIISE 270
Cdd:PTZ00286 243 YVEAKSAKNGVGIVKLMGRDSGFIALHASVASaDVNVCLIPE 284
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
70-309 |
6.05e-22 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 96.71 E-value: 6.05e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 70 VGVILSGGQAPGGHNVISG-----LFDGIKkvnrdsrLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGfDIIGSGRTK- 143
Cdd:cd00763 3 IGVLTSGGDAPGMNAAIRGvvrsaIAEGLE-------VYGIRDGYAGLIAGDIVPLDRYSVSDIINRGG-TFLGSARFPe 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 144 -LETKAQFdKGLEILKKLNIKALVIIGGDDSNTNAAILAEYyksinaGVQVIGCPKTIDGDLKNEmiETSFGFDTATKVY 222
Cdd:cd00763 75 fKDEEGQA-KAIEQLKKHGIDALVVIGGDGSYMGAMRLTEH------GFPCVGLPGTIDNDIPGT--DYTIGFDTALNTV 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 223 SEVIGNIqRDCNSSKKYWHFIKLMGRSASHIALECALQCQPNVCIISEEVEAKKEtlndivnsIADVVAARAANGNNFGS 302
Cdd:cd00763 146 VEAIDRI-RDTSSSHQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREE--------VANRIKAGIERGKKHAI 216
|
....*..
gi 1616153329 303 VLIPEGL 309
Cdd:cd00763 217 VVVAEGV 223
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
57-270 |
6.84e-19 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 89.16 E-value: 6.84e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 57 FEK-GPAVK----SAPINVGVILSGGQAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVD---HKYMELTASYIDEY 128
Cdd:PRK06830 65 FEKaGPREKiyfdPSKVKAAIVTCGGLCPGLNDVIRAIVLELHHHYGVRRILGIRYGYQGLIPrygHDPVELTPEVVADI 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 129 RNTGGfDIIGSGRtkletkAQFDKGlEI---LKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLK 205
Cdd:PRK06830 145 HEFGG-TILGSSR------GPQDPE-EIvdtLERMNINILFVIGGDGTLRGASAIAEEIERRGLKISVIGIPKTIDNDIN 216
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1616153329 206 neMIETSFGFDTATKVYSEVIGNIQRDCNSSKKYWHFIKLMGRSASHIALECALQCQP-NVCIISE 270
Cdd:PRK06830 217 --FIQKSFGFETAVEKATEAIRCAHVEANGAPNGIGLVKLMGRHSGFIAAYAALASKDvNFVLIPE 280
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
88-259 |
4.22e-15 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 77.21 E-value: 4.22e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 88 GLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTA-SY--IDEYRNT--GGFdiiGSGRTKL----ETKAQFDKGLEILK 158
Cdd:PRK14072 24 GVIEEARKHKKIGKVYGARNGIIGILDEDLIDLSKeSDeaLAALAHTpsGAL---GSCRYKLksleEDRAEYERLLEVFK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 159 KLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLknEMIETSFGFDTATKVYSEVIGNIQRD----CN 234
Cdd:PRK14072 101 AHDIGYFFYNGGNDSMDTALKVSQLAKKMGYPIRCIGIPKTIDNDL--PGTDHCPGFGSAAKYIATSVLEAALDvaamAN 178
|
170 180
....*....|....*....|....*
gi 1616153329 235 SSKKYwhFIKLMGRSASHIALECAL 259
Cdd:PRK14072 179 TSKVF--ILEVMGRHAGWLAAAAAL 201
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
55-270 |
8.54e-15 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 76.71 E-value: 8.54e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 55 IHFEK-GPAVK----SAPINVGVILSGGQAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTASYIDEYR 129
Cdd:PLN02564 70 THFRRaGPRQKvyfeSDEVRACIVTCGGLCPGLNTVIREIVCGLSYMYGVTRILGIDGGYRGFYSRNTIPLTPKVVNDIH 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 130 NTGGfDIIGSGRTKLETKAQFDKgleiLKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLknEMI 209
Cdd:PLN02564 150 KRGG-TILGTSRGGHDTSKIVDS----IQDRGINQVYIIGGDGTQKGASVIYEEIRRRGLKVAVAGIPKTIDNDI--PVI 222
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1616153329 210 ETSFGFDTATKVYSEVIGNIQRDCNSSKKYWHFIKLMGRSASHIALECALQCQP-NVCIISE 270
Cdd:PLN02564 223 DKSFGFDTAVEEAQRAINAAHVEAESVENGIGLVKLMGRYSGFIAMYATLASRDvDCCLIPE 284
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
70-308 |
7.95e-14 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 73.18 E-value: 7.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 70 VGVILSGGQAPGGHNVISGLfdgikkVNRDSRLYGF-----LMGPGGFVDH--KYMELTASYIDEYRNTGGfDIIGS--- 139
Cdd:PRK14071 7 IGILTSGGDCAGLNAVIRAV------VHRARGTYGWevigiRDATQGLMARppQYIELDLDQVDDLLRMGG-TILGTtnk 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 140 ----------GRTKletkaqfDKGLEIL---KKLNIKALVIIGGDDSntnAAILAEYYKSinAGVQVIGCPKTIDGDLKn 206
Cdd:PRK14071 80 gdpfafpmpdGSLR-------DRSQEIIdgyHSLGLDALIGIGGDGS---LAILRRLAQQ--GGINLVGIPKTIDNDVG- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 207 eMIETSFGFDTATKVYSEVIGNIQRDCNSSKKYWhFIKLMGRSASHIALECALQCQPNVCIISEeveaKKETLNDIVNSI 286
Cdd:PRK14071 147 -ATEVSIGFDTAVNIATEALDRLHFTAASHNRVM-ILEVMGRDAGHIALAAGIAGGADVILIPE----IPYTLENVCKKI 220
|
250 260
....*....|....*....|..
gi 1616153329 287 ADvvaaRAANGNNFGSVLIPEG 308
Cdd:PRK14071 221 RE----RQEEGKNFCLVVVSEA 238
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
54-270 |
1.22e-12 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 69.84 E-value: 1.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 54 EIHFEkgpavkSAPINVGVILSGGQAPGGHNVISGLF-----DGIKKVnrdsrlYGFLMGPGGFVDH--KYMELTASYID 126
Cdd:PLN02884 46 KIYFE------PEEVKAAIVTCGGLCPGLNDVIRQIVftleiYGVKNI------VGIPFGYRGFFEKglSEMPLSRKVVQ 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 127 EYRNTGGfDIIGSGRTKLETKAQFDKgleiLKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKn 206
Cdd:PLN02884 114 NIHLSGG-SLLGVSRGGAKTSDIVDS----IEARGINMLFVLGGNGTHAGANAIHNECRKRKMKVSVVGVPKTIDNDIL- 187
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1616153329 207 eMIETSFGFDTATKVYSEVIGNIQRDCNSSKKYWHFIKLMGRSASHIALECALQC-QPNVCIISE 270
Cdd:PLN02884 188 -LMDKTFGFDTAVEEAQRAINSAYIEAHSAYHGIGLVKLMGRSSGFIAMHASLASgQVDICLIPE 251
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
70-248 |
1.00e-09 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 60.41 E-value: 1.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 70 VGVILSGGQAPGGHNVISGLFDGIKKVNRDSRLYGFLMGPGGFVDHKYMELTasyiDEYRNT-------GGfDIIGSGRT 142
Cdd:PRK06555 6 VALLTAGGLAPCLSSAVGGLIERYTEIAPEVEIIAYRSGYQGLLLGDSIEIT----PAVRANagllhryGG-SPIGNSRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 143 KL-ETKAQFDKGL------------EILKKLNIKALVIIGGDDSNTNAAILAEYYKSINAGVQVIGCPKTIDGDLKNemI 209
Cdd:PRK06555 81 KLtNVADCVKRGLvkegenplkvaaERLAADGVDILHTIGGDDTNTTAADLAAYLAENGYDLTVVGLPKTIDNDVVP--I 158
|
170 180 190
....*....|....*....|....*....|....*....
gi 1616153329 210 ETSFGFDTATKVYSEVIGNIQRDCNSSKKYWHFIKLMGR 248
Cdd:PRK06555 159 RQSLGAWTAAEQGARFFDNVINEHSANPRMLIIHEVMGR 197
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
64-259 |
9.76e-08 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 55.04 E-value: 9.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 64 KSAPINVGVILSGGQAPGGHNVIS-----GLFDGIkkvnrdsRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGfDIIG 138
Cdd:TIGR02478 386 EASRLRIAIIHVGAPAGGMNAATRsavryALARGH-------TVIAIHNGFSGLARHDVRELTWSDVEGWVGEGG-SELG 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 139 SGRTKLEtkAQFDKGLEILKKLNIKALVIIGGDDSNTNAAILA---EYYKSINAGVQVIgcPKTIDGDLKNEmiETSFGF 215
Cdd:TIGR02478 458 TNRSLPG--DDLGTIAYYFQQHKIDGLIIIGGFEAFEALYQLDaarEKYPAFRIPMVVI--PATISNNVPGT--EYSLGS 531
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1616153329 216 DTATKVYSEVIGNIQRDCNSSKKYWHFIKLMGRSASHIALECAL 259
Cdd:TIGR02478 532 DTALNEITEYCDNIKQSASASKRRVFVVETMGGYSGYLATMAGL 575
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
69-271 |
5.11e-05 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 46.18 E-value: 5.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 69 NVGVILSGGQAPGGHNVI-----SGLFdgikkvnRDSRLYGFLMGPGGFVDHKYMELTASYID--EYRNTGGfDIIGSGR 141
Cdd:TIGR02478 2 RIAVLTSGGDAQGMNAAVravvrMAIY-------VGCRVYAIREGYQGLVDGGDNIEEAQWEDvrGILSLGG-TIIGTAR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 142 TK--LETKAQFdKGLEILKKLNIKALVIIGGDDSNTNAAILAEYY----------KSINAGVQ-------VIGCPKTIDg 202
Cdd:TIGR02478 74 CKefRERPGRL-KAARNLVSNGIDALVVIGGDGSLTGADLFREEWpslleelvdtGKITAEQAeehrhltIVGLVGSID- 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1616153329 203 dlkNEMIET--SFGFDTATKVYSEVIGNIQRDCNSSKKYWhFIKLMGRSASHIALECALQCQPNVCIISEE 271
Cdd:TIGR02478 152 ---NDMCGTdmTIGADSALHRICEAIDAISSTAQSHQRAF-VVEVMGRHCGYLALMAAIATGADYVFIPER 218
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
70-311 |
7.06e-04 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 42.50 E-value: 7.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 70 VGVILSGGQAPGGHN-----VISGLFDGikkvnrdSRLYGFLMGPGGFVD------HKYMELTASYIDEyrntgGFDIIG 138
Cdd:cd00764 6 IAVLTSGGDAQGMNAavravVRMGIYVG-------AKVFFVYEGYEGLVKggdyikQAEWESVSNWLQE-----GGTIIG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 139 SGRTK-LETKAQFDKGLEILKKLNIKALVIIGGDDSNTNAAILAEYYKSI-----------------NAGVQVIGCPKTI 200
Cdd:cd00764 74 SARCKeFREREGRLQAAYNLIQRGITNLCVIGGDGSLTGADLFRSEWPSLleelvkdgkiteeevakYQHLNIVGMVGSI 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 201 DGDLKNemIETSFGFDTATKVYSEVIGNIQRDCNSSKKYWhFIKLMGRSASHIALECALQCQPNVCIISEeveakKETLN 280
Cdd:cd00764 154 DNDFCG--TDMTIGTDSALHRICEVVDAITTTAQSHQRTF-VLEVMGRHCGYLALVSGLATGADWIFIPE-----RPPED 225
|
250 260 270
....*....|....*....|....*....|.
gi 1616153329 281 DIVNSIADVVAARAANGNNFGSVLIPEGLIE 311
Cdd:cd00764 226 GWEDQMCRRLSEHRSRGKRLNIIIVAEGAID 256
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
66-271 |
2.16e-03 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 40.96 E-value: 2.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 66 APINVGVILSGGQAPGGHNVISGLFDGikkvnrdSRLYGFLMGPGGFVDHKYMELTASYIDEYRNTGGfDIIGSGRTKle 145
Cdd:cd00764 393 AIVNVGAPAAGMNAAVRSAVRYGLAHG-------HRPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGG-SELGTKRTL-- 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1616153329 146 TKAQFDKGLEILKKLNIKALVIIGGDDSNTNAAILA---EYYKSINAGVQVIgcPKTIDGDLKNEmiETSFGFDTATKVY 222
Cdd:cd00764 463 PKKDLETIAYNFQKYGIDGLIIVGGFEAYKGLLQLRearEQYEEFCIPMVLI--PATVSNNVPGT--DFSLGSDTALNAL 538
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1616153329 223 SEVIGNIQRDCNSSKKYWHFIKLMGRSASHIALECALQCQPNVCIISEE 271
Cdd:cd00764 539 MKYCDRIKQSASGTKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEE 587
|
|
| |
