|
Name |
Accession |
Description |
Interval |
E-value |
| DPPIV_N |
pfam00930 |
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ... |
129-477 |
1.44e-94 |
|
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.
Pssm-ID: 395744 [Multi-domain] Cd Length: 352 Bit Score: 298.46 E-value: 1.44e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 129 SNDNDKVLVYTNTRRVWRYDTRGDYWVLDLNDGTFRQLGKglPESSLMFAKFSPDGNNVAYVSQNNIYVENLPTGNIKRI 208
Cdd:pfam00930 1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPP--GEGKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 209 TDDGSDTIVNGTFDWVYEEE-FGCRDGFRWSPDSKYIAYWQSDTEGTGTFDIINNVD-SIYPTIMHFPYPKAGSTNSAVK 286
Cdd:pfam00930 79 TSDGSDGIFNGVADWVYEEEvLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTDeGPGPEVREIKYPKAGAPNPTVE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 287 VGYVSASGGPTSWIELPGDPRNN--YIPRMEFIPESNeLFIQQMNRQQNTNNVWIASLDDNAPRKIFTDTDAAWLDTNDN 364
Cdd:pfam00930 159 LFVYDLASGKTVEVVPPDDLSDAdyYITRVKWVPDGK-LLVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 365 IL-WLNDNSWFTWASERNGWRHLYRISRDGKQMVPITKGDFDYISPVGTDLKKGLVYFIASPDNYTQRYLYSAELFGDGT 443
Cdd:pfam00930 238 PHfIKRDGSGFLWISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERHLYSVSLDSGGE 317
|
330 340 350
....*....|....*....|....*....|....*.
gi 1624566917 444 VKRLSPanQEGQHRYN--MSPTGKWAVHTFSNAATP 477
Cdd:pfam00930 318 PTCLTD--DSGDHDYSasFSPNGSYYVLTYSGPDTP 351
|
|
| DAP2 |
COG1506 |
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]; |
522-765 |
3.24e-54 |
|
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
Pssm-ID: 441115 [Multi-domain] Cd Length: 234 Bit Score: 186.76 E-value: 3.24e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 522 LTLDAWMIKPVDfdsTKKYPVIVEVYGEPASStvqdvWGGGDLWNQYMANLGYIVVSIDNRGanvpRGREWrkciyGEVG 601
Cdd:COG1506 8 TTLPGWLYLPAD---GKKYPVVVYVHGGPGSR-----DDSFLPLAQALASRGYAVLAPDYRG----YGESA-----GDWG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 602 TFASEDQARGVQDLARQySFIDSTRVGITGWSGGGSQTLNSMFRYPDIFHTGIAIAFVADQRTYDT---IYQERYMNTPQ 678
Cdd:COG1506 71 GDEVDDVLAAIDYLAAR-PYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGttrEYTERLMGGPW 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 679 DNPEGYVKGSPISHVEGLKGNLLLIHGTGDDNVHYQNCELLVNELIRHGKIFSQVSYPMRSHGIYERPgtTLHLRKTMAK 758
Cdd:COG1506 150 EDPEAYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAG--APDYLERILD 227
|
....*..
gi 1624566917 759 YWLDNLP 765
Cdd:COG1506 228 FLDRHLK 234
|
|
| Peptidase_S9 |
pfam00326 |
Prolyl oligopeptidase family; |
565-764 |
1.24e-42 |
|
Prolyl oligopeptidase family;
Pssm-ID: 459761 [Multi-domain] Cd Length: 213 Bit Score: 153.92 E-value: 1.24e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 565 WN-QYMANLGYIVVSIDNRGANvPRGREWRKCIYGEVGTFASEDQARGVQDLARQYsFIDSTRVGITGWSGGGSQTLNSM 643
Cdd:pfam00326 5 WNaQLLADRGYVVAIANGRGSG-GYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQG-YTDPDRLAIWGGSYGGYLTGAAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 644 FRYPDIFHTGIAIAFVADQRTYDTI----YQERYMN--TPQDNPEGYVKGSPISHVE--GLKGNLLLIHGTGDDNVHYQN 715
Cdd:pfam00326 83 NQRPDLFKAAVAHVPVVDWLAYMSDtslpFTERYMEwgNPWDNEEGYDYLSPYSPADnvKVYPPLLLIHGLLDDRVPPWQ 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1624566917 716 CELLVNELIRHGKIFSQVSYPMRSHGIYeRPGTTLHLRKTMAKYWLDNL 764
Cdd:pfam00326 163 SLKLVAALQRKGVPFLLLIFPDEGHGIG-KPRNKVEEYARELAFLLEYL 210
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
136-259 |
1.87e-10 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 60.07 E-value: 1.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 136 LVYTNTRrvwryDTRGDYWVLDLNDGTFRQLGKGlpESSLMFAKFSPDGNNVAYVS----QNNIYVENLPTGNIKRITDD 211
Cdd:COG0823 1 LAFTLSR-----DGNSDIYVVDLDGGEPRRLTNS--PGIDTSPAWSPDGRRIAFTSdrggGPQIYVVDADGGEPRRLTFG 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1624566917 212 GSDTIvngtfdwvyeeefgcrdGFRWSPDSKYIAYwqsDTEGTGTFDI 259
Cdd:COG0823 74 GGYNA-----------------SPSWSPDGKRLAF---VSRSDGRFDI 101
|
|
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
173-405 |
8.48e-04 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 42.64 E-value: 8.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 173 SSLMFAKFSPDGNNVAYVSQNN----IYVENLPTGNIKRITDDGSDTIVNgtfdwvyeeefgcrdgfRWSPDSKYIAYWQ 248
Cdd:TIGR02800 190 EPILSPAWSPDGQKLAYVSFESgkpeIYVQDLATGQREKVASFPGMNGAP-----------------AFSPDGSKLAVSL 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 249 SdteGTGTFDI-INNVDSIYPT-IMHFP----YPKAGSTNSavKVGYVS------------ASGGPTSWIELPGDpRN-- 308
Cdd:TIGR02800 253 S---KDGNPDIyVMDLDGKQLTrLTNGPgidtEPSWSPDGK--SIAFTSdrggspqiymmdADGGEVRRLTFRGG-YNas 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 309 -NYIPRMEFIpesneLFIQQMNRQQNtnnvwIASLD-DNAPRKIFTDTdaaWLDtnDNILWLNDNSWFTWASERNGWRHL 386
Cdd:TIGR02800 327 pSWSPDGDLI-----AFVHREGGGFN-----IAVMDlDGGGERVLTDT---GLD--ESPSFAPNGRMILYATTRGGRGVL 391
|
250
....*....|....*....
gi 1624566917 387 YRISRDGKQMVPITKGDFD 405
Cdd:TIGR02800 392 GLVSTDGRFRARLPLGNGD 410
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DPPIV_N |
pfam00930 |
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ... |
129-477 |
1.44e-94 |
|
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.
Pssm-ID: 395744 [Multi-domain] Cd Length: 352 Bit Score: 298.46 E-value: 1.44e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 129 SNDNDKVLVYTNTRRVWRYDTRGDYWVLDLNDGTFRQLGKglPESSLMFAKFSPDGNNVAYVSQNNIYVENLPTGNIKRI 208
Cdd:pfam00930 1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPP--GEGKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 209 TDDGSDTIVNGTFDWVYEEE-FGCRDGFRWSPDSKYIAYWQSDTEGTGTFDIINNVD-SIYPTIMHFPYPKAGSTNSAVK 286
Cdd:pfam00930 79 TSDGSDGIFNGVADWVYEEEvLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTDeGPGPEVREIKYPKAGAPNPTVE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 287 VGYVSASGGPTSWIELPGDPRNN--YIPRMEFIPESNeLFIQQMNRQQNTNNVWIASLDDNAPRKIFTDTDAAWLDTNDN 364
Cdd:pfam00930 159 LFVYDLASGKTVEVVPPDDLSDAdyYITRVKWVPDGK-LLVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 365 IL-WLNDNSWFTWASERNGWRHLYRISRDGKQMVPITKGDFDYISPVGTDLKKGLVYFIASPDNYTQRYLYSAELFGDGT 443
Cdd:pfam00930 238 PHfIKRDGSGFLWISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERHLYSVSLDSGGE 317
|
330 340 350
....*....|....*....|....*....|....*.
gi 1624566917 444 VKRLSPanQEGQHRYN--MSPTGKWAVHTFSNAATP 477
Cdd:pfam00930 318 PTCLTD--DSGDHDYSasFSPNGSYYVLTYSGPDTP 351
|
|
| DAP2 |
COG1506 |
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]; |
522-765 |
3.24e-54 |
|
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
Pssm-ID: 441115 [Multi-domain] Cd Length: 234 Bit Score: 186.76 E-value: 3.24e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 522 LTLDAWMIKPVDfdsTKKYPVIVEVYGEPASStvqdvWGGGDLWNQYMANLGYIVVSIDNRGanvpRGREWrkciyGEVG 601
Cdd:COG1506 8 TTLPGWLYLPAD---GKKYPVVVYVHGGPGSR-----DDSFLPLAQALASRGYAVLAPDYRG----YGESA-----GDWG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 602 TFASEDQARGVQDLARQySFIDSTRVGITGWSGGGSQTLNSMFRYPDIFHTGIAIAFVADQRTYDT---IYQERYMNTPQ 678
Cdd:COG1506 71 GDEVDDVLAAIDYLAAR-PYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGttrEYTERLMGGPW 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 679 DNPEGYVKGSPISHVEGLKGNLLLIHGTGDDNVHYQNCELLVNELIRHGKIFSQVSYPMRSHGIYERPgtTLHLRKTMAK 758
Cdd:COG1506 150 EDPEAYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAG--APDYLERILD 227
|
....*..
gi 1624566917 759 YWLDNLP 765
Cdd:COG1506 228 FLDRHLK 234
|
|
| Peptidase_S9 |
pfam00326 |
Prolyl oligopeptidase family; |
565-764 |
1.24e-42 |
|
Prolyl oligopeptidase family;
Pssm-ID: 459761 [Multi-domain] Cd Length: 213 Bit Score: 153.92 E-value: 1.24e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 565 WN-QYMANLGYIVVSIDNRGANvPRGREWRKCIYGEVGTFASEDQARGVQDLARQYsFIDSTRVGITGWSGGGSQTLNSM 643
Cdd:pfam00326 5 WNaQLLADRGYVVAIANGRGSG-GYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQG-YTDPDRLAIWGGSYGGYLTGAAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 644 FRYPDIFHTGIAIAFVADQRTYDTI----YQERYMN--TPQDNPEGYVKGSPISHVE--GLKGNLLLIHGTGDDNVHYQN 715
Cdd:pfam00326 83 NQRPDLFKAAVAHVPVVDWLAYMSDtslpFTERYMEwgNPWDNEEGYDYLSPYSPADnvKVYPPLLLIHGLLDDRVPPWQ 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1624566917 716 CELLVNELIRHGKIFSQVSYPMRSHGIYeRPGTTLHLRKTMAKYWLDNL 764
Cdd:pfam00326 163 SLKLVAALQRKGVPFLLLIFPDEGHGIG-KPRNKVEEYARELAFLLEYL 210
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
136-259 |
1.87e-10 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 60.07 E-value: 1.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 136 LVYTNTRrvwryDTRGDYWVLDLNDGTFRQLGKGlpESSLMFAKFSPDGNNVAYVS----QNNIYVENLPTGNIKRITDD 211
Cdd:COG0823 1 LAFTLSR-----DGNSDIYVVDLDGGEPRRLTNS--PGIDTSPAWSPDGRRIAFTSdrggGPQIYVVDADGGEPRRLTFG 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1624566917 212 GSDTIvngtfdwvyeeefgcrdGFRWSPDSKYIAYwqsDTEGTGTFDI 259
Cdd:COG0823 74 GGYNA-----------------SPSWSPDGKRLAF---VSRSDGRFDI 101
|
|
| COG4099 |
COG4099 |
Predicted peptidase [General function prediction only]; |
508-727 |
3.01e-10 |
|
Predicted peptidase [General function prediction only];
Pssm-ID: 443275 [Multi-domain] Cd Length: 235 Bit Score: 61.14 E-value: 3.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 508 GLNPKEFVKVKSGElTLDAWMIKPVDFDSTKKYPVIVEV--YGEPASS-TVQDVWGGG---DLWNQymANLGYIVVSidn 581
Cdd:COG4099 18 GFEARTFTDPSDGD-TLPYRLYLPKGYDPGKKYPLVLFLhgAGERGTDnEKQLTHGAPkfiNPENQ--AKFPAIVLA--- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 582 rgANVPRGREWRKCIYgevgtfasEDQARGVQDLARQYSFIDSTRVGITGWSGGGSQTLNSMFRYPDIFhtgIAIAFVAD 661
Cdd:COG4099 92 --PQCPEDDYWSDTKA--------LDAVLALLDDLIAEYRIDPDRIYLTGLSMGGYGTWDLAARYPDLF---AAAVPICG 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1624566917 662 QrtYDTIYQERYMNTPqdnpegyvkgspishveglkgnLLLIHGTGDDNVHYQNCELLVNELIRHG 727
Cdd:COG4099 159 G--GDPANAANLKKVP----------------------VWIFHGAKDDVVPVEESRAMVEALKAAG 200
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
151-405 |
7.52e-10 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 62.75 E-value: 7.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 151 GDYWVLDLNDGTFRQL--GKGlPESslmFAKFSPDGNNVAYVSQ----NNIYVENLPTGNIKRITDDGSDTIVNGtfdwv 224
Cdd:COG4946 41 GDLWTVPADGGRARRLtsHPG-YES---FPRFSPDGKWIAFTSDydgnTDVYVMPAEGGEPKRLTYHPANDRVVG----- 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 225 yeeefgcrdgfrWSPDSKYIAYwqsdteGTGTFDIINNVDSIYptimhfpypkagstnsavkvgYVSASGGPTSwiELPg 304
Cdd:COG4946 112 ------------WTPDGKSVLF------ASNRGSPPSRSNQLY---------------------TVPVDGGLPE--RLP- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 305 dprnnyIPRMEFI---PESNELFIQQMNRQQNT---------NNVWIASLDDNAPRKIfTDTDAawldtND-NILWLNDN 371
Cdd:COG4946 150 ------LPPAGDGsfsPDGKKLAYTRIGREFRTwkryrggtaGDIWIYDLGTGEFTRL-TDFGG-----NDrNPMWIGDR 217
|
250 260 270
....*....|....*....|....*....|....*
gi 1624566917 372 SWFTwaSERNGWRHLYRISRDGKQMVPITKG-DFD 405
Cdd:COG4946 218 IYFL--SDRDGTFNLYSYDPDGKDLRQLTHFkDFD 250
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
113-255 |
8.05e-10 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 58.14 E-value: 8.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 113 IDKSTGNHVPI-------RSIIWSNDNDKvLVYTNTRrvwryDTRGDYWVLDLNDGTFRQLGKGlpESSLMFAKFSPDGN 185
Cdd:COG0823 16 VDLDGGEPRRLtnspgidTSPAWSPDGRR-IAFTSDR-----GGGPQIYVVDADGGEPRRLTFG--GGYNASPSWSPDGK 87
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1624566917 186 NVAYVSQNN----IYVENLPTGNIKRITDDGSdtivngtfdwvyeeefgcrdGFRWSPDSKYIAYwQSDTEGTG 255
Cdd:COG0823 88 RLAFVSRSDgrfdIYVLDLDGGAPRRLTDGPG--------------------SPSWSPDGRRIVF-SSDRGGRP 140
|
|
| DLH |
COG0412 |
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism]; |
513-741 |
9.36e-10 |
|
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 440181 [Multi-domain] Cd Length: 226 Bit Score: 59.59 E-value: 9.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 513 EFVKVKS-GELTLDAWMIKPvdfDSTKKYPVIVeVygepasstVQDVWGGGDlWNQYMAN----LGYIVVSID-----NR 582
Cdd:COG0412 4 ETVTIPTpDGVTLPGYLARP---AGGGPRPGVV-V--------LHEIFGLNP-HIRDVARrlaaAGYVVLAPDlygrgGP 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 583 GANVPRGREWrkciygeVGTFaseDQARGVQDL------ARQYSFIDSTRVGITGWSGGGSQTLNSMFRYPDIfhtGIAI 656
Cdd:COG0412 71 GDDPDEARAL-------MGAL---DPELLAADLraaldwLKAQPEVDAGRVGVVGFCFGGGLALLAAARGPDL---AAAV 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 657 AFvadqrtydtiyqerYMNTPQDNPEGYVKgspishveGLKGNLLLIHGTGDDNVHYQNCELLVNELIRHGKIFSQVSYP 736
Cdd:COG0412 138 SF--------------YGGLPADDLLDLAA--------RIKAPVLLLYGEKDPLVPPEQVAALEAALAAAGVDVELHVYP 195
|
....*
gi 1624566917 737 MRSHG 741
Cdd:COG0412 196 GAGHG 200
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
336-486 |
1.00e-09 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 57.76 E-value: 1.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 336 NVWIASLDDNAPRKIftdTDAAWLDTNdnILWLNDNSWFTWASERNGWRHLYRISRDGKQMVPITKGDFDYISPV----G 411
Cdd:COG0823 12 DIYVVDLDGGEPRRL---TNSPGIDTS--PAWSPDGRRIAFTSDRGGGPQIYVVDADGGEPRRLTFGGGYNASPSwspdG 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1624566917 412 TdlkkgLVYFIASPDNYTQRYLYSAElfgDGTVKRLSpanqEGQHRYNMSPTGKWAVHTfSNAATPSIIDMVSFP 486
Cdd:COG0823 87 K-----RLAFVSRSDGRFDIYVLDLD---GGAPRRLT----DGPGSPSWSPDGRRIVFS-SDRGGRPDLYVVDLD 148
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
124-246 |
1.08e-09 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 61.98 E-value: 1.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 124 RSIIWSNDNDKVlvytntrrVWRYDTRGDY--WVLDLND-GTFRQLGKGlpESSLMFA-KFSPDGNNVAYVSQ-NNIYVE 198
Cdd:COG4946 346 RLPAWSPDGKSI--------AYFSDASGEYelYIAPADGsGEPKQLTLG--DLGRVFNpVWSPDGKKIAFTDNrGRLWVV 415
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1624566917 199 NLPTGNIKRITDDGSDTIVNgtfdwvyeeefgcrdGFRWSPDSKYIAY 246
Cdd:COG4946 416 DLASGKVRKVDTDGYGDGIS---------------DLAWSPDSKWLAY 448
|
|
| FrsA |
COG1073 |
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ... |
504-709 |
1.93e-08 |
|
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];
Pssm-ID: 440691 [Multi-domain] Cd Length: 253 Bit Score: 56.08 E-value: 1.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 504 YKALGLNPKEFVKVKSGE-LTLDAWMIKPVDfdSTKKYPVIVEVYGepasstvqdvWGG----GDLWNQYMANLGYIVVS 578
Cdd:COG1073 2 FPPSDKVNKEDVTFKSRDgIKLAGDLYLPAG--ASKKYPAVVVAHG----------NGGvkeqRALYAQRLAELGFNVLA 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 579 IDNRGanvprgrewrkciYGE-------VGTFASEDqARGVQDLARQYSFIDSTRVGITGWSGGGSQTLNSMFRYPDifh 651
Cdd:COG1073 70 FDYRG-------------YGEsegepreEGSPERRD-ARAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPR--- 132
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1624566917 652 tgiaIAFVADQRTYDTI-----YQERYMNTPQDNPEGYVKG-----------SPISHVEGLKGNLLLIHGTGDD 709
Cdd:COG1073 133 ----VKAVILDSPFTSLedlaaQRAKEARGAYLPGVPYLPNvrlasllndefDPLAKIEKISRPLLFIHGEKDE 202
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
123-258 |
4.46e-08 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 56.97 E-value: 4.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 123 IRSIIWSNDNDKVLVYTNTRRVWrydtrgdywVLDLNDGTFRQLGKGLPESSLMFAKFSPDGNNVAYVSQ-----NNIYV 197
Cdd:COG4946 391 VFNPVWSPDGKKIAFTDNRGRLW---------VVDLASGKVRKVDTDGYGDGISDLAWSPDSKWLAYSKPgpnqlSQIFL 461
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1624566917 198 ENLPTGNIKRITDDGSdtivngtfdwvyeeefgcrDGF--RWSPDSKYIaYWQSDTEGTGTFD 258
Cdd:COG4946 462 YDVETGKTVQLTDGRY-------------------DDGspAFSPDGKYL-YFLSSRDFNPTYG 504
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
187-395 |
4.82e-07 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 50.06 E-value: 4.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 187 VAYVS----QNNIYVENLPTGNIKRITDDGsdtivngtfdwvyeeefGCRDGFRWSPDSKYIAYWqSDTEGTGtfdiinn 262
Cdd:COG0823 1 LAFTLsrdgNSDIYVVDLDGGEPRRLTNSP-----------------GIDTSPAWSPDGRRIAFT-SDRGGGP------- 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 263 vdSIYptimhfpypkagstnsavkvgYVSASGGPTSwiELPGDPRNNYIPRmeFIPESNELFIQQmnRQQNTNNVWIASL 342
Cdd:COG0823 56 --QIY---------------------VVDADGGEPR--RLTFGGGYNASPS--WSPDGKRLAFVS--RSDGRFDIYVLDL 106
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1624566917 343 DDNAPRKIFTDTDAAWldtndnilWLNDNSWFTWASERNGWRHLYRISRDGKQ 395
Cdd:COG0823 107 DGGAPRRLTDGPGSPS--------WSPDGRRIVFSSDRGGRPDLYVVDLDGRK 151
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
150-410 |
7.11e-07 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 53.12 E-value: 7.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 150 RGDYWVLDLNDGTFRQLGKgLPESSLMFAKFSPDGNNVAYVS----QNNIYVENL-PTGNIKRITDDGSdtivngtfdwv 224
Cdd:COG4946 321 RGEVFTVPAEKGPTRNLTN-TPGVRERLPAWSPDGKSIAYFSdasgEYELYIAPAdGSGEPKQLTLGDL----------- 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 225 yeeefGCRDGFRWSPDSKYIAYwqsdtegtgtfdiinnVDsiyptimhfpypkagstnsavkvgyvsasggptswielpg 304
Cdd:COG4946 389 -----GRVFNPVWSPDGKKIAF----------------TD---------------------------------------- 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 305 dprnnyiprmefipesnelfiqqmnrqqNTNNVWIASLDDNAPRKIFTDTdaaWLDTNDNILWLNDNSWFTWA-SERNGW 383
Cdd:COG4946 408 ----------------------------NRGRLWVVDLASGKVRKVDTDG---YGDGISDLAWSPDSKWLAYSkPGPNQL 456
|
250 260
....*....|....*....|....*..
gi 1624566917 384 RHLYRISRDGKQMVPITKGDFDYISPV 410
Cdd:COG4946 457 SQIFLYDVETGKTVQLTDGRYDDGSPA 483
|
|
| LpqC |
COG3509 |
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ... |
515-715 |
1.53e-06 |
|
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];
Pssm-ID: 442732 [Multi-domain] Cd Length: 284 Bit Score: 50.39 E-value: 1.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 515 VKVKSGELTLDAWMIKPVDFDSTKKYPVIVEVYGepASSTVQDVWGGGDlWNQYMANLGYIVVSIDnrGANVPRGREWRk 594
Cdd:COG3509 28 RTFTVGGGTRTYRLYVPAGYDGGAPLPLVVALHG--CGGSAADFAAGTG-LNALADREGFIVVYPE--GTGRAPGRCWN- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 595 ciygevgTFASEDQARG----------VQDLARQYSfIDSTRVGITGWSGGGSQTLNSMFRYPDIFHtgiAIAFVAdqrt 664
Cdd:COG3509 102 -------WFDGRDQRRGrddvafiaalVDDLAARYG-IDPKRVYVTGLSAGGAMAYRLACEYPDVFA---AVAPVA---- 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1624566917 665 ydtiyqeryMNTPQDNPEGYVK-GSPIShveglkgnLLLIHGTGDDNVHYQN 715
Cdd:COG3509 167 ---------GLPYGAASDAACApGRPVP--------VLVIHGTADPTVPYAG 201
|
|
| Fes |
COG2382 |
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism]; |
513-727 |
1.99e-05 |
|
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];
Pssm-ID: 441948 [Multi-domain] Cd Length: 314 Bit Score: 47.15 E-value: 1.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 513 EFVKVKSGEL--TLDAWMIKPVDFD-STKKYPVIVEVYGEPasSTVQDVWGGGDLwNQYMANL-------GYIVVSIDNr 582
Cdd:COG2382 82 ETVTYPSKALgrTRRVWVYLPPGYDnPGKKYPVLYLLDGGG--GDEQDWFDQGRL-PTILDNLiaagkipPMIVVMPDG- 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 583 gaNVPRGREWRKCIYGEVGTFASEDQargVQDLARQYSFI-DSTRVGITGWSGGGSQTLNSMFRYPDIFHTGIAI--AFV 659
Cdd:COG2382 158 --GDGGDRGTEGPGNDAFERFLAEEL---IPFVEKNYRVSaDPEHRAIAGLSMGGLAALYAALRHPDLFGYVGSFsgSFW 232
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1624566917 660 ADQRTYDTIYQERYMNTPQDNPegyvkgspishveGLKgnLLLIHGTGDDNvhYQNCELLVNELIRHG 727
Cdd:COG2382 233 WPPGDADRGGWAELLAAGAPKK-------------PLR--FYLDVGTEDDL--LEANRALAAALKAKG 283
|
|
| YpfH |
COG0400 |
Predicted esterase [General function prediction only]; |
567-742 |
4.76e-04 |
|
Predicted esterase [General function prediction only];
Pssm-ID: 440169 [Multi-domain] Cd Length: 200 Bit Score: 42.20 E-value: 4.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 567 QYMANLGYIVVSIDNRGANVPRGREWRKcIYGEVGTFASEDQARGVQDLAR-------QYSfIDSTRVGITGWSGGGSQT 639
Cdd:COG0400 26 PELALPGAAVLAPRAPVPEGPGGRAWFD-LSFLEGREDEEGLAAAAEALAAfideleaRYG-IDPERIVLAGFSQGAAMA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 640 LNSMFRYPDIFHTGIAIA--FVADQRTYDtiyqerymntpqdnPEGYVKGSPIshveglkgnlLLIHGTGDDNVHYQNCE 717
Cdd:COG0400 104 LSLALRRPELLAGVVALSgyLPGEEALPA--------------PEAALAGTPV----------FLAHGTQDPVIPVERAR 159
|
170 180
....*....|....*....|....*
gi 1624566917 718 LLVNELIRHGKIFSQVSYPMrSHGI 742
Cdd:COG0400 160 EAAEALEAAGADVTYREYPG-GHEI 183
|
|
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
173-405 |
8.48e-04 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 42.64 E-value: 8.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 173 SSLMFAKFSPDGNNVAYVSQNN----IYVENLPTGNIKRITDDGSDTIVNgtfdwvyeeefgcrdgfRWSPDSKYIAYWQ 248
Cdd:TIGR02800 190 EPILSPAWSPDGQKLAYVSFESgkpeIYVQDLATGQREKVASFPGMNGAP-----------------AFSPDGSKLAVSL 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 249 SdteGTGTFDI-INNVDSIYPT-IMHFP----YPKAGSTNSavKVGYVS------------ASGGPTSWIELPGDpRN-- 308
Cdd:TIGR02800 253 S---KDGNPDIyVMDLDGKQLTrLTNGPgidtEPSWSPDGK--SIAFTSdrggspqiymmdADGGEVRRLTFRGG-YNas 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624566917 309 -NYIPRMEFIpesneLFIQQMNRQQNtnnvwIASLD-DNAPRKIFTDTdaaWLDtnDNILWLNDNSWFTWASERNGWRHL 386
Cdd:TIGR02800 327 pSWSPDGDLI-----AFVHREGGGFN-----IAVMDlDGGGERVLTDT---GLD--ESPSFAPNGRMILYATTRGGRGVL 391
|
250
....*....|....*....
gi 1624566917 387 YRISRDGKQMVPITKGDFD 405
Cdd:TIGR02800 392 GLVSTDGRFRARLPLGNGD 410
|
|
| |
