conjugative transfer ATPase similar to TraC, one of the proteins encoded by the transfer (tra) region of the F pilus assembly Type-IV secretion system for plasmid transfer; is required for the assembly of mature F-pilin subunits into extended F pili
conjugative transfer ATPase, PFL_4706 family; Members of this protein family are predicted ...
2-893
0e+00
conjugative transfer ATPase, PFL_4706 family; Members of this protein family are predicted ATP-binding proteins apparently associated with DNA conjugal transfer. Members are found both in plasmids and in bacterial chromosomal regions that appear to derive from integrative elements such as conjugative transposons. More distant homologs, outside the scope of this family, include type IV secretion/conjugal transfer proteins such as TraC, VirB4 and TrsE. The granularity of this protein family definition is chosen so as to represent one distinctive clade and act as a marker through which to define and recognize the class of mobile element it serves. [Mobile and extrachromosomal element functions, Plasmid functions]
:
Pssm-ID: 274761 [Multi-domain] Cd Length: 893 Bit Score: 1517.27 E-value: 0e+00
conjugative transfer ATPase, PFL_4706 family; Members of this protein family are predicted ...
2-893
0e+00
conjugative transfer ATPase, PFL_4706 family; Members of this protein family are predicted ATP-binding proteins apparently associated with DNA conjugal transfer. Members are found both in plasmids and in bacterial chromosomal regions that appear to derive from integrative elements such as conjugative transposons. More distant homologs, outside the scope of this family, include type IV secretion/conjugal transfer proteins such as TraC, VirB4 and TrsE. The granularity of this protein family definition is chosen so as to represent one distinctive clade and act as a marker through which to define and recognize the class of mobile element it serves. [Mobile and extrachromosomal element functions, Plasmid functions]
Pssm-ID: 274761 [Multi-domain] Cd Length: 893 Bit Score: 1517.27 E-value: 0e+00
TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a ...
14-282
2.65e-68
TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a cytoplasmic, peripheral membrane protein and is one of the proteins encoded by the F transfer region of the conjugative plasmid that is required for the assembly of F pilin into the mature F pilus structure. F pili are filamentous appendages that help establish the physical contact between donor and recipient cells involved in the conjugation process.
Pssm-ID: 431669 [Multi-domain] Cd Length: 232 Bit Score: 226.78 E-value: 2.65e-68
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
478-616
2.06e-03
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 39.66 E-value: 2.06e-03
conjugative transfer ATPase, PFL_4706 family; Members of this protein family are predicted ...
2-893
0e+00
conjugative transfer ATPase, PFL_4706 family; Members of this protein family are predicted ATP-binding proteins apparently associated with DNA conjugal transfer. Members are found both in plasmids and in bacterial chromosomal regions that appear to derive from integrative elements such as conjugative transposons. More distant homologs, outside the scope of this family, include type IV secretion/conjugal transfer proteins such as TraC, VirB4 and TrsE. The granularity of this protein family definition is chosen so as to represent one distinctive clade and act as a marker through which to define and recognize the class of mobile element it serves. [Mobile and extrachromosomal element functions, Plasmid functions]
Pssm-ID: 274761 [Multi-domain] Cd Length: 893 Bit Score: 1517.27 E-value: 0e+00
TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a ...
14-282
2.65e-68
TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a cytoplasmic, peripheral membrane protein and is one of the proteins encoded by the F transfer region of the conjugative plasmid that is required for the assembly of F pilin into the mature F pilus structure. F pili are filamentous appendages that help establish the physical contact between donor and recipient cells involved in the conjugation process.
Pssm-ID: 431669 [Multi-domain] Cd Length: 232 Bit Score: 226.78 E-value: 2.65e-68
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found ...
313-873
7.17e-12
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).
Pssm-ID: 273346 [Multi-domain] Cd Length: 785 Bit Score: 69.27 E-value: 7.17e-12
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
478-616
2.06e-03
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 39.66 E-value: 2.06e-03
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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This image shows a graphical summary of conserved domains identified on the query sequence.
The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits
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Domains are color coded according to superfamilies
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if a domain or superfamily has been annotated with functional sites (conserved features),
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click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.
The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
Click on the domain model's accession number to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.
To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page,
or click on the triangles, if present, that represent functional sites (conserved features)
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Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence.
(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
(labeled illustration) Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance.
(labeled illustration) Four types of hits can be shown, as available,
for each region on the query sequence:
specific hits meet or exceed a domain-specific e-value threshold
(illustrated example)
and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits
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the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains
Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool
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